Quick search
In Drug search, users can search candidate drugs/compounds that associate with Shelterin.
Result
This table shows chemicals/drugs, their mechanism of action(MOA) and association with shelterin.
| Chemical | Cancer | MOA | Association | ||
|---|---|---|---|---|---|
| Midostaurin | TGCT | FLT3 inhibitor|KIT inhibitor|PKC inhibitor | negatively | ||
| Mitomycin-C | ESCA | DNA alkylating agent|DNA synthesis inhibitor | negatively | ||
| Mitomycin-C | THYM | DNA alkylating agent|DNA synthesis inhibitor | negatively | ||
| MK-2206 | UVM | AKT inhibitor | negatively | ||
| MK-2206 | THYM | AKT inhibitor | negatively | ||
| MK-2206 | UCEC | AKT inhibitor | negatively | ||
| MK-2206 | ESCA | AKT inhibitor | negatively | ||
| MK-2206 | PAAD | AKT inhibitor | negatively | ||
| MS-275 | THYM | HDAC inhibitor | negatively | ||
| Nilotinib | UVM | Abl kinase inhibitor|Bcr-Abl kinase inhibitor | negatively | ||
| Nilotinib | ESCA | Abl kinase inhibitor|Bcr-Abl kinase inhibitor | negatively | ||
| Nilotinib | PAAD | Abl kinase inhibitor|Bcr-Abl kinase inhibitor | negatively | ||
| NSC-87877 | TGCT | SHP1/2 PTPase inhibitor | negatively | ||
| NSC-87877 | ESCA | SHP1/2 PTPase inhibitor | negatively | ||
| NU-7441 | LGG | DNA dependent protein kinase inhibitor | negatively | ||
| NU-7441 | ESCA | DNA dependent protein kinase inhibitor | negatively | ||
| NU-7441 | PAAD | DNA dependent protein kinase inhibitor | negatively | ||
| NU-7441 | BLCA | DNA dependent protein kinase inhibitor | negatively | ||
| Nutlin-3a | THYM | MDM2 antagonist | negatively | ||
| NVP-BEZ235 | PAAD | mTOR inhibitor|PI3K inhibitor | negatively | ||