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In Drug search, users can search candidate drugs/compounds that associate with Shelterin.
Result
This table shows chemicals/drugs, their mechanism of action(MOA) and association with shelterin.
| Chemical | Cancer | MOA | Association | ||
|---|---|---|---|---|---|
| KU-55933 | PAAD | ATM kinase inhibitor | negatively | ||
| Lapatinib | ACC | EGFR inhibitor | negatively | ||
| Lapatinib | ESCA | EGFR inhibitor | negatively | ||
| Lapatinib | KIRP | EGFR inhibitor | negatively | ||
| Lapatinib | KICH | EGFR inhibitor | negatively | ||
| Lapatinib | TGCT | EGFR inhibitor | negatively | ||
| Lenalidomide | UVM | anticancer agent | negatively | ||
| Lenalidomide | CHOL | anticancer agent | negatively | ||
| Lenalidomide | PAAD | anticancer agent | negatively | ||
| Lenalidomide | THYM | anticancer agent | negatively | ||
| LFM-A13 | ACC | Bruton's tyrosine kinase (BTK) inhibitor | negatively | ||
| LFM-A13 | KIRP | Bruton's tyrosine kinase (BTK) inhibitor | negatively | ||
| LFM-A13 | TGCT | Bruton's tyrosine kinase (BTK) inhibitor | negatively | ||
| LFM-A13 | ESCA | Bruton's tyrosine kinase (BTK) inhibitor | negatively | ||
| Metformin | THYM | insulin sensitizer | negatively | ||
| Methotrexate | THYM | dihydrofolate reductase inhibitor | negatively | ||
| Methotrexate | UVM | dihydrofolate reductase inhibitor | negatively | ||
| Methotrexate | PAAD | dihydrofolate reductase inhibitor | negatively | ||
| Midostaurin | COAD | FLT3 inhibitor|KIT inhibitor|PKC inhibitor | negatively | ||
| Midostaurin | ESCA | FLT3 inhibitor|KIT inhibitor|PKC inhibitor | negatively | ||