Quick search
In Drug search, users can search candidate drugs/compounds that associate with Shelterin.
Result
This table shows chemicals/drugs, their mechanism of action(MOA) and association with shelterin.
| Chemical | Cancer | MOA | Association | ||
|---|---|---|---|---|---|
| NVP-BEZ235 | ESCA | mTOR inhibitor|PI3K inhibitor | negatively | ||
| NVP-BEZ235 | BLCA | mTOR inhibitor|PI3K inhibitor | negatively | ||
| NVP-TAE684 | TGCT | ALK tyrosine kinase receptor inhibitor | negatively | ||
| Obatoclax-Mesylate | ESCA | BCL2 antagonist | negatively | ||
| Obatoclax-Mesylate | THYM | BCL2 antagonist | negatively | ||
| Obatoclax-Mesylate | THCA | BCL2 antagonist | negatively | ||
| OSI-906 | GBM | IGF-1R inhibitor | negatively | ||
| OSI-906 | KICH | IGF-1R inhibitor | negatively | ||
| OSI-906 | LGG | IGF-1R inhibitor | negatively | ||
| OSI-906 | TGCT | IGF-1R inhibitor | negatively | ||
| PAC-1 | THYM | caspase activator | negatively | ||
| PAC-1 | KICH | caspase activator | negatively | ||
| PAC-1 | UCEC | caspase activator | negatively | ||
| Paclitaxel | ESCA | tubulin polymerization inhibitor | negatively | ||
| Paclitaxel | THYM | tubulin polymerization inhibitor | negatively | ||
| Parthenolide | TGCT | NFkB pathway inhibitor | negatively | ||
| Pazopanib | PAAD | KIT inhibitor|PDGFR tyrosine kinase receptor inhibitor|VEGFR inhibitor | negatively | ||
| Pazopanib | TGCT | KIT inhibitor|PDGFR tyrosine kinase receptor inhibitor|VEGFR inhibitor | negatively | ||
| Pazopanib | KIRP | KIT inhibitor|PDGFR tyrosine kinase receptor inhibitor|VEGFR inhibitor | negatively | ||
| Pazopanib | ESCA | KIT inhibitor|PDGFR tyrosine kinase receptor inhibitor|VEGFR inhibitor | negatively | ||