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In Drug search, users can search candidate drugs/compounds that associate with Shelterin.

Result

This table shows chemicals/drugs, their mechanism of action(MOA) and association with shelterin.

Chemical Cancer MOA Association
CI-1040 CHOL MEK inhibitor negatively
CI-1040 THYM MEK inhibitor negatively
CI-1040 UVM MEK inhibitor negatively
Cisplatin UVM DNA alkylating agent|DNA synthesis inhibitor negatively
Cisplatin SKCM DNA alkylating agent|DNA synthesis inhibitor negatively
Cisplatin PAAD DNA alkylating agent|DNA synthesis inhibitor negatively
Cisplatin ESCA DNA alkylating agent|DNA synthesis inhibitor negatively
Cisplatin BLCA DNA alkylating agent|DNA synthesis inhibitor negatively
CMK THYM RSK inhibitor negatively
CMK ESCA RSK inhibitor negatively
Cyclopamine THYM Hedgehog inhibitor negatively
Cytarabine THYM ribonucleotide reductase inhibitor negatively
Cytarabine PAAD ribonucleotide reductase inhibitor negatively
Cytarabine ESCA ribonucleotide reductase inhibitor negatively
Dasatinib TGCT Bcr-Abl kinase inhibitor|ephrin inhibitor|KIT inhibitor|PDGFR tyrosine kinase receptor inhibitor|src inhibitor|tyrosine kinase inhibitor negatively
Dasatinib ESCA Bcr-Abl kinase inhibitor|ephrin inhibitor|KIT inhibitor|PDGFR tyrosine kinase receptor inhibitor|src inhibitor|tyrosine kinase inhibitor negatively
Docetaxel ESCA tubulin polymerization inhibitor negatively
Doxorubicin THYM topoisomerase inhibitor negatively
Doxorubicin ESCA topoisomerase inhibitor negatively
EHT-1864 GBM Rac inhibitor negatively
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