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In Drug search, users can search candidate drugs/compounds that associate with Shelterin.
Result
This table shows chemicals/drugs, their mechanism of action(MOA) and association with shelterin.
| Chemical | Cancer | MOA | Association | ||
|---|---|---|---|---|---|
| SB-216763 | GBM | glycogen synthase kinase inhibitor | positively | ||
| SB-216763 | PCPG | glycogen synthase kinase inhibitor | positively | ||
| SB-216763 | KICH | glycogen synthase kinase inhibitor | positively | ||
| SB-216763 | DLBC | glycogen synthase kinase inhibitor | positively | ||
| SB590885 | DLBC | Raf inhibitor | positively | ||
| SB590885 | TGCT | Raf inhibitor | positively | ||
| SB590885 | PRAD | Raf inhibitor | positively | ||
| SB590885 | GBM | Raf inhibitor | positively | ||
| SB590885 | ESCA | Raf inhibitor | positively | ||
| SB590885 | ACC | Raf inhibitor | positively | ||
| SB590885 | KIRP | Raf inhibitor | positively | ||
| Shikonin | LUSC | Chloride channel inhibitor | positively | ||
| Shikonin | PCPG | Chloride channel inhibitor | positively | ||
| Shikonin | GBM | Chloride channel inhibitor | positively | ||
| Shikonin | BRCA | Chloride channel inhibitor | positively | ||
| SL-0101-1 | KICH | RSK inhibitor | positively | ||
| SL-0101-1 | TGCT | RSK inhibitor | positively | ||
| Sorafenib | THYM | FLT3 inhibitor|KIT inhibitor|PDGFR tyrosine kinase receptor inhibitor|RAF inhibitor|RET tyrosine kinase inhibitor|VEGFR inhibitor | positively | ||
| Sorafenib | GBM | FLT3 inhibitor|KIT inhibitor|PDGFR tyrosine kinase receptor inhibitor|RAF inhibitor|RET tyrosine kinase inhibitor|VEGFR inhibitor | positively | ||
| Sorafenib | TGCT | FLT3 inhibitor|KIT inhibitor|PDGFR tyrosine kinase receptor inhibitor|RAF inhibitor|RET tyrosine kinase inhibitor|VEGFR inhibitor | positively | ||