Quick search
In Drug search, users can search candidate drugs/compounds that associate with Shelterin.
Result
This table shows chemicals/drugs, their mechanism of action(MOA) and association with shelterin.
| Chemical | Cancer | MOA | Association | ||
|---|---|---|---|---|---|
| Parthenolide | UCEC | NFkB pathway inhibitor | positively | ||
| Parthenolide | PCPG | NFkB pathway inhibitor | positively | ||
| Pazopanib | UVM | KIT inhibitor|PDGFR tyrosine kinase receptor inhibitor|VEGFR inhibitor | positively | ||
| Pazopanib | SARC | KIT inhibitor|PDGFR tyrosine kinase receptor inhibitor|VEGFR inhibitor | positively | ||
| Pazopanib | CHOL | KIT inhibitor|PDGFR tyrosine kinase receptor inhibitor|VEGFR inhibitor | positively | ||
| Pazopanib | BRCA | KIT inhibitor|PDGFR tyrosine kinase receptor inhibitor|VEGFR inhibitor | positively | ||
| Pazopanib | GBM | KIT inhibitor|PDGFR tyrosine kinase receptor inhibitor|VEGFR inhibitor | positively | ||
| Pazopanib | PCPG | KIT inhibitor|PDGFR tyrosine kinase receptor inhibitor|VEGFR inhibitor | positively | ||
| Pazopanib | LGG | KIT inhibitor|PDGFR tyrosine kinase receptor inhibitor|VEGFR inhibitor | positively | ||
| Pazopanib | THYM | KIT inhibitor|PDGFR tyrosine kinase receptor inhibitor|VEGFR inhibitor | positively | ||
| PD-0325901 | PAAD | MEK inhibitor | positively | ||
| PD-0325901 | THYM | MEK inhibitor | positively | ||
| PD-0325901 | GBM | MEK inhibitor | positively | ||
| PD-0325901 | ESCA | MEK inhibitor | positively | ||
| PD-0332991 | UCEC | EGFR inhibitor | positively | ||
| PD-0332991 | UVM | EGFR inhibitor | positively | ||
| PD-173074 | TGCT | FGFR inhibitor|VEGFR inhibitor | positively | ||
| PD-173074 | PCPG | FGFR inhibitor|VEGFR inhibitor | positively | ||
| PD-173074 | KICH | FGFR inhibitor|VEGFR inhibitor | positively | ||
| PF-02341066 | PCPG | ALK/c-Met inhibitor | positively | ||