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In Drug search, users can search candidate drugs/compounds that associate with Shelterin.

Result

This table shows chemicals/drugs, their mechanism of action(MOA) and association with shelterin.

Chemical Cancer MOA Association
Tipifarnib THYM farnesyltransferase inhibitor negatively
TW-37 ESCA BCL inhibitor negatively
TW-37 PAAD BCL inhibitor negatively
Vinblastine THYM microtubule inhibitor|tubulin polymerization inhibitor negatively
Vinblastine ESCA microtubule inhibitor|tubulin polymerization inhibitor negatively
Vinorelbine ESCA tubulin polymerization inhibitor negatively
Vinorelbine THYM tubulin polymerization inhibitor negatively
Vorinostat THYM HDAC inhibitor negatively
Vorinostat THCA HDAC inhibitor negatively
Vorinostat GBM HDAC inhibitor negatively
Vorinostat LGG HDAC inhibitor negatively
VX-680 THYM Aurora kinase inhibitor negatively
VX-702 CHOL p38 MAPK inhibitor negatively
VX-702 PAAD p38 MAPK inhibitor negatively
VX-702 UVM p38 MAPK inhibitor negatively
VX-702 THYM p38 MAPK inhibitor negatively
VX-702 BRCA p38 MAPK inhibitor negatively
WH-4-023 TGCT src inhibitor negatively
WH-4-023 ESCA src inhibitor negatively
WO2009093972 ACC PI3K inhibitor negatively
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