ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003779 actin binding 48/386 443/18639 0.108352144469526 5.23206119369817 3.5747548187826e-21 2.41295950267825e-18 GO:0005201 extracellular matrix structural constituent 28/386 168/18639 0.166666666666667 8.0479274611399 1.18237346124594e-17 3.99051043170504e-15 GO:0051015 actin filament binding 22/386 209/18639 0.105263157894737 5.08290155440415 4.53280440518635e-10 1.01988099116693e-07 GO:0030020 extracellular matrix structural constituent conferring tensile strength 11/386 44/18639 0.25 12.0718911917098 1.08350560874624e-09 1.82841571475928e-07 GO:0045296 cadherin binding 27/386 334/18639 0.0808383233532934 3.90348577456486 1.83278620612941e-09 2.47426137827471e-07 GO:0005178 integrin binding 17/386 161/18639 0.105590062111801 5.0986869629582 4.24023450236933e-08 4.7702638151655e-06 GO:0005516 calmodulin binding 18/386 207/18639 0.0869565217391304 4.19891867537734 3.31447600623784e-07 3.19610186315792e-05 GO:0048407 platelet-derived growth factor binding 5/386 11/18639 0.454545454545455 21.9488930758361 1.54765006293295e-06 0.000130582974059968 GO:0030695 GTPase regulator activity 27/386 489/18639 0.0552147239263804 2.66618455767825 4.08741623131519e-06 0.000286515909237051 GO:0060589 nucleoside-triphosphatase regulator activity 27/386 490/18639 0.0551020408163265 2.66074336470339 4.2446801368452e-06 0.000286515909237051 GO:0005096 GTPase activator activity 18/386 271/18639 0.0664206642066421 3.20729212473472 1.52306980113016e-05 0.000934611014329874 GO:0019838 growth factor binding 12/386 136/18639 0.0882352941176471 4.260667479427 2.64806627706693e-05 0.00148953728085015 GO:0005518 collagen binding 8/386 72/18639 0.111111111111111 5.36528497409326 0.000118481235901045 0.0057647718509975 GO:0000146 microfilament motor activity 6/386 38/18639 0.157894736842105 7.62435233160622 0.000119565638391059 0.0057647718509975 GO:0017124 SH3 domain binding 10/386 115/18639 0.0869565217391304 4.19891867537734 0.000139638081235225 0.00628371365558511 GO:0050840 extracellular matrix binding 7/386 67/18639 0.104477611940299 5.04496945325188 0.000462243687896809 0.0195009055831466 GO:0005522 profilin binding 3/386 10/18639 0.3 14.4862694300518 0.000949036408505348 0.0352213218145914 GO:0008093 cytoskeletal anchor activity 4/386 22/18639 0.181818181818182 8.77955723033443 0.000985636864852401 0.0352213218145914 GO:0098631 cell adhesion mediator activity 7/386 76/18639 0.0921052631578947 4.44753886010363 0.00099141498441072 0.0352213218145914 GO:0046332 SMAD binding 7/386 79/18639 0.0886075949367089 4.2786449793402 0.00124691396830433 0.0420833464302711 GO:0003774 cytoskeletal motor activity 10/386 153/18639 0.065359477124183 3.15604998476074 0.00134564317258755 0.0432528162617427 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 14/386 268/18639 0.0522388059701493 2.52248472662594 0.0014687719991665 0.0442172830096349 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 5/386 41/18639 0.121951219512195 5.88872741059017 0.0015066629766246 0.0442172830096349 GO:0004674 protein serine/threonine kinase activity 19/386 433/18639 0.0438799076212471 2.1188538812239 0.00182067808012664 0.0512065710035617 GO:0001217 DNA-binding transcription repressor activity 14/386 278/18639 0.0503597122302158 2.43174786595594 0.00206487724711728 0.0557516856721665 GO:0031267 small GTPase binding 14/386 283/18639 0.049469964664311 2.38878412274117 0.00243088114396903 0.0603097635363006 GO:0051020 GTPase binding 15/386 315/18639 0.0476190476190476 2.29940784603997 0.00249288195220109 0.0603097635363006 GO:0051393 alpha-actinin binding 4/386 28/18639 0.142857142857143 6.89822353811991 0.00250173833928358 0.0603097635363006 GO:0005161 platelet-derived growth factor receptor binding 3/386 14/18639 0.214285714285714 10.3473353071799 0.00270677954481763 0.0630026273362723 GO:0019955 cytokine binding 9/386 144/18639 0.0625 3.01797279792746 0.0031241477901048 0.0702824282948906 GO:0001968 fibronectin binding 4/386 30/18639 0.133333333333333 6.43834196891192 0.0032413599137431 0.0702824282948906 GO:0051371 muscle alpha-actinin binding 3/386 15/18639 0.2 9.65751295336788 0.00333190771175778 0.0702824282948906 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 19/386 484/18639 0.0392561983471074 1.89558622018584 0.00607770034343757 0.12431659793395 GO:0008083 growth factor activity 9/386 162/18639 0.0555555555555556 2.68264248704663 0.00672689933543551 0.132064991540132 GO:0042805 actinin binding 4/386 37/18639 0.108108108108108 5.22027727209074 0.0069739723436143 0.132064991540132 GO:0001216 DNA-binding transcription activator activity 19/386 491/18639 0.0386965376782077 1.8685615693889 0.00704346621547369 0.132064991540132 GO:0005085 guanyl-nucleotide exchange factor activity 11/386 230/18639 0.0478260869565217 2.30940527145754 0.0086986574604023 0.152209488117345 GO:0009975 cyclase activity 3/386 21/18639 0.142857142857143 6.89822353811991 0.00888512215104124 0.152209488117345 GO:0051010 microtubule plus-end binding 3/386 21/18639 0.142857142857143 6.89822353811991 0.00888512215104124 0.152209488117345 GO:0042578 phosphoric ester hydrolase activity 15/386 363/18639 0.0413223140495868 1.9953539159851 0.00901982151806489 0.152209488117345 GO:0030021 extracellular matrix structural constituent conferring compression resistance 3/386 22/18639 0.136363636363636 6.58466792275082 0.0101324093014921 0.166814055573346 GO:0008307 structural constituent of muscle 4/386 42/18639 0.0952380952380952 4.59881569207994 0.010903419253231 0.175233523712642 GO:0016849 phosphorus-oxygen lyase activity 3/386 23/18639 0.130434782608696 6.29837801306601 0.0114761992403358 0.176055329255152 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 3/386 23/18639 0.130434782608696 6.29837801306601 0.0114761992403358 0.176055329255152 GO:0005539 glycosaminoglycan binding 11/386 242/18639 0.0454545454545455 2.19488930758361 0.0124042408598032 0.181655007471856 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 3/386 24/18639 0.125 6.03594559585492 0.0129176894202209 0.181655007471856 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 3/386 24/18639 0.125 6.03594559585492 0.0129176894202209 0.181655007471856 GO:0050431 transforming growth factor beta binding 3/386 24/18639 0.125 6.03594559585492 0.0129176894202209 0.181655007471856 GO:0097110 scaffold protein binding 5/386 70/18639 0.0714285714285714 3.44911176905996 0.0149687386897118 0.206202012562357 GO:0004112 cyclic-nucleotide phosphodiesterase activity 3/386 26/18639 0.115384615384615 5.57164208848147 0.016097532105635 0.213055571986346 GO:0030507 spectrin binding 3/386 26/18639 0.115384615384615 5.57164208848147 0.016097532105635 0.213055571986346 GO:0031434 mitogen-activated protein kinase kinase binding 2/386 10/18639 0.2 9.65751295336788 0.0172454069365031 0.223858647733453 GO:0035591 signaling adaptor activity 7/386 129/18639 0.0542635658914729 2.62025545246415 0.0179696549937413 0.228858813599536 GO:0106310 protein serine kinase activity 14/386 361/18639 0.038781163434903 1.87264794109626 0.0188172935687097 0.233911960716335 GO:0051019 mitogen-activated protein kinase binding 3/386 28/18639 0.107142857142857 5.17366765358993 0.0196775474794877 0.233911960716335 GO:0019001 guanyl nucleotide binding 15/386 400/18639 0.0375 1.81078367875648 0.0201415386923095 0.233911960716335 GO:0032561 guanyl ribonucleotide binding 15/386 400/18639 0.0375 1.81078367875648 0.0201415386923095 0.233911960716335 GO:0004143 ATP-dependent diacylglycerol kinase activity 2/386 11/18639 0.181818181818182 8.77955723033443 0.0207921742858964 0.233911960716335 GO:0034713 type I transforming growth factor beta receptor binding 2/386 11/18639 0.181818181818182 8.77955723033443 0.0207921742858964 0.233911960716335 GO:0140031 phosphorylation-dependent protein binding 2/386 11/18639 0.181818181818182 8.77955723033443 0.0207921742858964 0.233911960716335 GO:0044325 transmembrane transporter binding 7/386 136/18639 0.0514705882352941 2.48538936299909 0.0232527842546528 0.257305399539191 GO:0005078 MAP-kinase scaffold activity 2/386 12/18639 0.166666666666667 8.0479274611399 0.0246131934975437 0.259592275169406 GO:0017166 vinculin binding 2/386 12/18639 0.166666666666667 8.0479274611399 0.0246131934975437 0.259592275169406 GO:0045295 gamma-catenin binding 2/386 12/18639 0.166666666666667 8.0479274611399 0.0246131934975437 0.259592275169406 GO:0017147 Wnt-protein binding 3/386 31/18639 0.0967741935483871 4.67299013872639 0.0258032391428924 0.267956714176191 GO:0004222 metalloendopeptidase activity 6/386 110/18639 0.0545454545454545 2.63386716910033 0.02691828139664 0.271799932960957 GO:0098632 cell-cell adhesion mediator activity 4/386 55/18639 0.0727272727272727 3.51182289213377 0.026978660012421 0.271799932960957 GO:0005172 vascular endothelial growth factor receptor binding 2/386 13/18639 0.153846153846154 7.42885611797529 0.0286956458601307 0.273408270773837 GO:0046975 histone H3K36 methyltransferase activity 2/386 13/18639 0.153846153846154 7.42885611797529 0.0286956458601307 0.273408270773837 GO:0140333 glycerophospholipid flippase activity 2/386 13/18639 0.153846153846154 7.42885611797529 0.0286956458601307 0.273408270773837 GO:0005126 cytokine receptor binding 11/386 275/18639 0.04 1.93150259067358 0.0287584995925073 0.273408270773837 GO:0004721 phosphoprotein phosphatase activity 8/386 175/18639 0.0457142857142857 2.20743153219837 0.0296315648141196 0.277208619981593 GO:0004860 protein kinase inhibitor activity 5/386 84/18639 0.0595238095238095 2.87425980754996 0.0302881128262362 0.277208619981593 GO:0071889 14-3-3 protein binding 3/386 33/18639 0.0909090909090909 4.38977861516722 0.0303902783387227 0.277208619981593 GO:0008194 UDP-glycosyltransferase activity 7/386 145/18639 0.0482758620689655 2.33112381633018 0.0315016319436391 0.283514687492752 GO:0008376 acetylgalactosaminyltransferase activity 3/386 34/18639 0.0882352941176471 4.260667479427 0.0328337974692858 0.291615964365367 GO:0008081 phosphoric diester hydrolase activity 5/386 87/18639 0.0574712643678161 2.77514740039307 0.0345049367273837 0.300594966314428 GO:0035091 phosphatidylinositol binding 11/386 284/18639 0.0387323943661972 1.87029300153251 0.0351153162911534 0.300594966314428 GO:0001098 basal transcription machinery binding 4/386 60/18639 0.0666666666666667 3.21917098445596 0.03562607008171 0.300594966314428 GO:0001099 basal RNA polymerase II transcription machinery binding 4/386 60/18639 0.0666666666666667 3.21917098445596 0.03562607008171 0.300594966314428 GO:0030553 cGMP binding 2/386 15/18639 0.133333333333333 6.43834196891192 0.0375956183282097 0.309476126482214 GO:0031005 filamin binding 2/386 15/18639 0.133333333333333 6.43834196891192 0.0375956183282097 0.309476126482214 GO:0019210 kinase inhibitor activity 5/386 90/18639 0.0555555555555556 2.68264248704663 0.0390681614560097 0.314908374121324 GO:1901981 phosphatidylinositol phosphate binding 8/386 185/18639 0.0432432432432432 2.0881109088363 0.0391885976684315 0.314908374121324 GO:0030551 cyclic nucleotide binding 3/386 37/18639 0.0810810810810811 3.91520795406806 0.0407571480200327 0.317921325700486 GO:0005024 transforming growth factor beta receptor activity 2/386 16/18639 0.125 6.03594559585492 0.0423895100933982 0.317921325700486 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 2/386 16/18639 0.125 6.03594559585492 0.0423895100933982 0.317921325700486 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/386 16/18639 0.125 6.03594559585492 0.0423895100933982 0.317921325700486 GO:0140327 flippase activity 2/386 16/18639 0.125 6.03594559585492 0.0423895100933982 0.317921325700486 GO:0140328 floppase activity 2/386 16/18639 0.125 6.03594559585492 0.0423895100933982 0.317921325700486 GO:0043531 ADP binding 3/386 38/18639 0.0789473684210526 3.81217616580311 0.0435932286764076 0.32335636655577 GO:0019902 phosphatase binding 8/386 190/18639 0.0421052631578947 2.03316062176166 0.0446614535653628 0.327679143006738 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 2/386 17/18639 0.117647058823529 5.68088997256934 0.0473975563103856 0.340354792654364 GO:0019198 transmembrane receptor protein phosphatase activity 2/386 17/18639 0.117647058823529 5.68088997256934 0.0473975563103856 0.340354792654364 GO:0005525 GTP binding 13/386 378/18639 0.0343915343915344 1.6606834443622 0.0521153103519579 0.350478981082503 GO:0000900 mRNA regulatory element binding translation repressor activity 2/386 18/18639 0.111111111111111 5.36528497409326 0.0526088812801528 0.350478981082503 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/386 18/18639 0.111111111111111 5.36528497409326 0.0526088812801528 0.350478981082503 GO:0008525 phosphatidylcholine transporter activity 2/386 18/18639 0.111111111111111 5.36528497409326 0.0526088812801528 0.350478981082503 GO:0070064 proline-rich region binding 2/386 18/18639 0.111111111111111 5.36528497409326 0.0526088812801528 0.350478981082503 GO:0098641 cadherin binding involved in cell-cell adhesion 2/386 18/18639 0.111111111111111 5.36528497409326 0.0526088812801528 0.350478981082503 GO:0042169 SH2 domain binding 3/386 41/18639 0.0731707317073171 3.5332364463541 0.0526726260231816 0.350478981082503 GO:0004725 protein tyrosine phosphatase activity 5/386 98/18639 0.0510204081632653 2.46365126361425 0.0529612682524671 0.350478981082503 GO:0005543 phospholipid binding 16/386 497/18639 0.0321931589537223 1.55452924802702 0.0552006179936036 0.353334956506011 GO:0051879 Hsp90 protein binding 3/386 42/18639 0.0714285714285714 3.44911176905996 0.0558856419285624 0.353334956506011 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 2/386 19/18639 0.105263157894737 5.08290155440415 0.0580129658605778 0.353334956506011 GO:0030506 ankyrin binding 2/386 19/18639 0.105263157894737 5.08290155440415 0.0580129658605778 0.353334956506011 GO:0042800 histone H3K4 methyltransferase activity 2/386 19/18639 0.105263157894737 5.08290155440415 0.0580129658605778 0.353334956506011 GO:0016791 phosphatase activity 10/386 273/18639 0.0366300366300366 1.76877526618459 0.0587584088656111 0.353334956506011 GO:0008017 microtubule binding 10/386 276/18639 0.036231884057971 1.74954944807389 0.0622861041141923 0.353334956506011 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2/386 20/18639 0.1 4.82875647668394 0.0635996374256929 0.353334956506011 GO:0140303 intramembrane lipid transporter activity 3/386 45/18639 0.0666666666666667 3.21917098445596 0.0660662024423947 0.353334956506011 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 9/386 243/18639 0.037037037037037 1.78842832469775 0.0668769887547378 0.353334956506011 GO:0005123 death receptor binding 2/386 21/18639 0.0952380952380952 4.59881569207994 0.0693590600861825 0.353334956506011 GO:0035613 RNA stem-loop binding 2/386 21/18639 0.0952380952380952 4.59881569207994 0.0693590600861825 0.353334956506011 GO:0036122 BMP binding 2/386 21/18639 0.0952380952380952 4.59881569207994 0.0693590600861825 0.353334956506011 GO:0070851 growth factor receptor binding 6/386 139/18639 0.0431654676258993 2.08435531367652 0.0693859978525464 0.353334956506011 GO:0004676 3-phosphoinositide-dependent protein kinase activity 9/386 245/18639 0.036734693877551 1.77382890980226 0.0696200729115548 0.353334956506011 GO:0004711 ribosomal protein S6 kinase activity 9/386 245/18639 0.036734693877551 1.77382890980226 0.0696200729115548 0.353334956506011 GO:0035175 histone H3S10 kinase activity 9/386 245/18639 0.036734693877551 1.77382890980226 0.0696200729115548 0.353334956506011 GO:0035979 histone H2AXS139 kinase activity 9/386 245/18639 0.036734693877551 1.77382890980226 0.0696200729115548 0.353334956506011 GO:0044022 histone H3S28 kinase activity 9/386 245/18639 0.036734693877551 1.77382890980226 0.0696200729115548 0.353334956506011 GO:0044023 histone H4S1 kinase activity 9/386 245/18639 0.036734693877551 1.77382890980226 0.0696200729115548 0.353334956506011 GO:0044024 histone H2AS1 kinase activity 9/386 245/18639 0.036734693877551 1.77382890980226 0.0696200729115548 0.353334956506011 GO:0044025 histone H2BS14 kinase activity 9/386 245/18639 0.036734693877551 1.77382890980226 0.0696200729115548 0.353334956506011 GO:0072354 histone H3T3 kinase activity 9/386 245/18639 0.036734693877551 1.77382890980226 0.0696200729115548 0.353334956506011 GO:0072371 histone H2AS121 kinase activity 9/386 245/18639 0.036734693877551 1.77382890980226 0.0696200729115548 0.353334956506011 GO:0072518 Rho-dependent protein serine/threonine kinase activity 9/386 245/18639 0.036734693877551 1.77382890980226 0.0696200729115548 0.353334956506011 GO:0140823 histone H2BS36 kinase activity 9/386 245/18639 0.036734693877551 1.77382890980226 0.0696200729115548 0.353334956506011 GO:0140855 histone H3S57 kinase activity 9/386 245/18639 0.036734693877551 1.77382890980226 0.0696200729115548 0.353334956506011 GO:0140995 histone H2A kinase activity 9/386 245/18639 0.036734693877551 1.77382890980226 0.0696200729115548 0.353334956506011 GO:0140997 histone H4 kinase activity 9/386 245/18639 0.036734693877551 1.77382890980226 0.0696200729115548 0.353334956506011 GO:0140998 histone H2B kinase activity 9/386 245/18639 0.036734693877551 1.77382890980226 0.0696200729115548 0.353334956506011 GO:1990244 histone H2AT120 kinase activity 9/386 245/18639 0.036734693877551 1.77382890980226 0.0696200729115548 0.353334956506011 GO:0004677 DNA-dependent protein kinase activity 9/386 246/18639 0.0365853658536585 1.76661822317705 0.0710176211908792 0.355088105954396 GO:0140857 histone H3T45 kinase activity 9/386 246/18639 0.0365853658536585 1.76661822317705 0.0710176211908792 0.355088105954396 GO:0035402 histone H3T11 kinase activity 9/386 247/18639 0.0364372469635627 1.75946592267836 0.0724325375640875 0.355905371847174 GO:0035403 histone H3T6 kinase activity 9/386 247/18639 0.0364372469635627 1.75946592267836 0.0724325375640875 0.355905371847174 GO:0017022 myosin binding 4/386 76/18639 0.0526315789473684 2.54145077720207 0.0728460523058125 0.355905371847174 GO:0001784 phosphotyrosine residue binding 3/386 47/18639 0.0638297872340425 3.08218498511741 0.0732901432396403 0.355905371847174 GO:0004679 AMP-activated protein kinase activity 9/386 248/18639 0.0362903225806452 1.7523713020224 0.0738648413264216 0.356134056395247 GO:0019207 kinase regulator activity 10/386 287/18639 0.0348432055749129 1.68249354588291 0.0763775043705646 0.365636989008022 GO:0032266 phosphatidylinositol-3-phosphate binding 3/386 48/18639 0.0625 3.01797279792746 0.0770285968560165 0.366157062519797 GO:0060590 ATPase regulator activity 3/386 49/18639 0.0612244897959184 2.9563815163371 0.0808492261056241 0.379318675356991 GO:1902936 phosphatidylinositol bisphosphate binding 5/386 111/18639 0.045045045045045 2.17511553003781 0.0809213174094914 0.379318675356991 GO:0005200 structural constituent of cytoskeleton 5/386 112/18639 0.0446428571428571 2.15569485566247 0.0833443537819338 0.386530409906008 GO:0019887 protein kinase regulator activity 9/386 255/18639 0.0352941176470588 1.7042669917708 0.084378815799114 0.386530409906008 GO:0032813 tumor necrosis factor receptor superfamily binding 3/386 50/18639 0.06 2.89725388601036 0.0847503713571692 0.386530409906008 GO:0048020 CCR chemokine receptor binding 3/386 50/18639 0.06 2.89725388601036 0.0847503713571692 0.386530409906008 GO:0001091 RNA polymerase II general transcription initiation factor binding 2/386 24/18639 0.0833333333333333 4.02396373056995 0.0875803285101781 0.388925800949804 GO:0005540 hyaluronic acid binding 2/386 24/18639 0.0833333333333333 4.02396373056995 0.0875803285101781 0.388925800949804 GO:0048027 mRNA 5'-UTR binding 2/386 24/18639 0.0833333333333333 4.02396373056995 0.0875803285101781 0.388925800949804 GO:0050699 WW domain binding 2/386 24/18639 0.0833333333333333 4.02396373056995 0.0875803285101781 0.388925800949804 GO:0008237 metallopeptidase activity 7/386 184/18639 0.0380434782608696 1.83702692047759 0.0886939349535037 0.391296771853693 GO:0004857 enzyme inhibitor activity 13/386 416/18639 0.03125 1.50898639896373 0.0933779763105595 0.403877020131648 GO:0003707 nuclear steroid receptor activity 2/386 25/18639 0.08 3.86300518134715 0.0939388032009908 0.403877020131648 GO:0005251 delayed rectifier potassium channel activity 2/386 25/18639 0.08 3.86300518134715 0.0939388032009908 0.403877020131648 GO:0017025 TBP-class protein binding 2/386 25/18639 0.08 3.86300518134715 0.0939388032009908 0.403877020131648 GO:1990782 protein tyrosine kinase binding 5/386 117/18639 0.0427350427350427 2.06357114388202 0.0960258737974093 0.408880400958775 GO:0005246 calcium channel regulator activity 3/386 53/18639 0.0566037735849057 2.73325838302864 0.0969197987457836 0.408880400958775 GO:0140296 general transcription initiation factor binding 3/386 53/18639 0.0566037735849057 2.73325838302864 0.0969197987457836 0.408880400958775 GO:0004435 phosphatidylinositol phospholipase C activity 2/386 26/18639 0.0769230769230769 3.71442805898764 0.10042557579227 0.41587278318885 GO:0005112 Notch binding 2/386 26/18639 0.0769230769230769 3.71442805898764 0.10042557579227 0.41587278318885 GO:0005160 transforming growth factor beta receptor binding 2/386 26/18639 0.0769230769230769 3.71442805898764 0.10042557579227 0.41587278318885 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 4/386 86/18639 0.0465116279069767 2.24593324496927 0.103184780904447 0.424693457990864 GO:0015631 tubulin binding 12/386 385/18639 0.0311688311688312 1.50506695377162 0.105460830225699 0.431430669105134 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 2/386 27/18639 0.0740740740740741 3.57685664939551 0.107032639278495 0.435223081403518 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 11/386 349/18639 0.0315186246418338 1.52195762875425 0.111144352981249 0.448296498441901 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 4/386 89/18639 0.0449438202247191 2.17022762997031 0.113256565208797 0.448296498441901 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 4/386 89/18639 0.0449438202247191 2.17022762997031 0.113256565208797 0.448296498441901 GO:0046875 ephrin receptor binding 2/386 28/18639 0.0714285714285714 3.44911176905996 0.113752261724572 0.448296498441901 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 2/386 28/18639 0.0714285714285714 3.44911176905996 0.113752261724572 0.448296498441901 GO:0005125 cytokine activity 8/386 234/18639 0.0341880341880342 1.65085691510562 0.114232589232603 0.448296498441901 GO:0099106 ion channel regulator activity 6/386 160/18639 0.0375 1.81078367875648 0.115713848878553 0.451484670479903 GO:0140793 histone H2AXY142 phosphatase activity 4/386 90/18639 0.0444444444444444 2.14611398963731 0.116707188639159 0.45216366883461 GO:0141003 histone H2AX kinase activity 11/386 354/18639 0.0310734463276836 1.50046105207693 0.119327284236806 0.45216366883461 GO:0072341 modified amino acid binding 4/386 91/18639 0.043956043956044 2.12253031942151 0.120203286162367 0.45216366883461 GO:0003785 actin monomer binding 2/386 29/18639 0.0689655172413793 3.33017688047168 0.120576978355896 0.45216366883461 GO:0004629 phospholipase C activity 2/386 29/18639 0.0689655172413793 3.33017688047168 0.120576978355896 0.45216366883461 GO:0043236 laminin binding 2/386 29/18639 0.0689655172413793 3.33017688047168 0.120576978355896 0.45216366883461 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 2/386 29/18639 0.0689655172413793 3.33017688047168 0.120576978355896 0.45216366883461 GO:0004879 nuclear receptor activity 3/386 59/18639 0.0508474576271186 2.45529990339861 0.123195272606479 0.454408792400948 GO:0015459 potassium channel regulator activity 3/386 59/18639 0.0508474576271186 2.45529990339861 0.123195272606479 0.454408792400948 GO:0045309 protein phosphorylated amino acid binding 3/386 59/18639 0.0508474576271186 2.45529990339861 0.123195272606479 0.454408792400948 GO:0140996 histone H3 kinase activity 11/386 357/18639 0.030812324929972 1.48785213567292 0.12439625291172 0.456344949540278 GO:0048019 receptor antagonist activity 2/386 30/18639 0.0666666666666667 3.21917098445596 0.127499583856688 0.463805484686563 GO:0098531 ligand-modulated transcription factor activity 3/386 60/18639 0.05 2.41437823834197 0.12780417800252 0.463805484686563 GO:0035173 histone kinase activity 11/386 360/18639 0.0305555555555556 1.47545336787565 0.129583453831232 0.467747761155517 GO:0016247 channel regulator activity 6/386 168/18639 0.0357142857142857 1.72455588452998 0.136632475725425 0.490568729333309 GO:0051059 NF-kappaB binding 2/386 32/18639 0.0625 3.01797279792746 0.141610892704325 0.504912179949727 GO:0141108 transporter regulator activity 6/386 170/18639 0.0352941176470588 1.7042669917708 0.142123428430293 0.504912179949727 GO:0008201 heparin binding 6/386 172/18639 0.0348837209302326 1.68444993372695 0.147714822756801 0.522028823878747 GO:0003712 transcription coregulator activity 14/386 495/18639 0.0282828282828283 1.36570890249647 0.149333353621283 0.525000071324824 GO:0003924 GTPase activity 10/386 331/18639 0.0302114803625378 1.45883881470814 0.151007848272864 0.528136256912868 GO:0015020 glucuronosyltransferase activity 2/386 34/18639 0.0588235294117647 2.84044498628467 0.156033454883189 0.542899907454396 GO:0061631 ubiquitin conjugating enzyme activity 2/386 35/18639 0.0571428571428571 2.75928941524796 0.163345992105144 0.543251889391693 GO:0004713 protein tyrosine kinase activity 5/386 140/18639 0.0357142857142857 1.72455588452998 0.165538297016953 0.543251889391693 GO:0003777 microtubule motor activity 3/386 68/18639 0.0441176470588235 2.1303337397135 0.166700525125984 0.543251889391693 GO:0005548 phospholipid transporter activity 3/386 68/18639 0.0441176470588235 2.1303337397135 0.166700525125984 0.543251889391693 GO:0000993 RNA polymerase II complex binding 2/386 36/18639 0.0555555555555556 2.68264248704663 0.170718228604633 0.543251889391693 GO:0055106 ubiquitin-protein transferase regulator activity 2/386 36/18639 0.0555555555555556 2.68264248704663 0.170718228604633 0.543251889391693 GO:0002039 p53 binding 3/386 69/18639 0.0434782608695652 2.09945933768867 0.171787576534565 0.543251889391693 GO:0020037 heme binding 5/386 142/18639 0.0352112676056338 1.70026636502956 0.172352236750165 0.543251889391693 GO:0008013 beta-catenin binding 4/386 106/18639 0.0377358490566038 1.82217225535243 0.177566167286281 0.543251889391693 GO:0043394 proteoglycan binding 2/386 37/18639 0.0540540540540541 2.61013863604537 0.17814457606661 0.543251889391693 GO:0019903 protein phosphatase binding 5/386 144/18639 0.0347222222222222 1.67665155440415 0.17927276303237 0.543251889391693 GO:0042379 chemokine receptor binding 3/386 72/18639 0.0416666666666667 2.01198186528497 0.187304214734319 0.543251889391693 GO:0001094 TFIID-class transcription factor complex binding 1/386 10/18639 0.1 4.82875647668394 0.188862884733513 0.543251889391693 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/386 10/18639 0.1 4.82875647668394 0.188862884733513 0.543251889391693 GO:0004955 prostaglandin receptor activity 1/386 10/18639 0.1 4.82875647668394 0.188862884733513 0.543251889391693 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 1/386 10/18639 0.1 4.82875647668394 0.188862884733513 0.543251889391693 GO:0008519 ammonium channel activity 1/386 10/18639 0.1 4.82875647668394 0.188862884733513 0.543251889391693 GO:0015643 toxic substance binding 1/386 10/18639 0.1 4.82875647668394 0.188862884733513 0.543251889391693 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/386 10/18639 0.1 4.82875647668394 0.188862884733513 0.543251889391693 GO:0019911 structural constituent of myelin sheath 1/386 10/18639 0.1 4.82875647668394 0.188862884733513 0.543251889391693 GO:0043121 neurotrophin binding 1/386 10/18639 0.1 4.82875647668394 0.188862884733513 0.543251889391693 GO:0051864 histone H3K36 demethylase activity 1/386 10/18639 0.1 4.82875647668394 0.188862884733513 0.543251889391693 GO:0070097 delta-catenin binding 1/386 10/18639 0.1 4.82875647668394 0.188862884733513 0.543251889391693 GO:0070513 death domain binding 1/386 10/18639 0.1 4.82875647668394 0.188862884733513 0.543251889391693 GO:0070739 protein-glutamic acid ligase activity 1/386 10/18639 0.1 4.82875647668394 0.188862884733513 0.543251889391693 GO:0070740 tubulin-glutamic acid ligase activity 1/386 10/18639 0.1 4.82875647668394 0.188862884733513 0.543251889391693 GO:0099122 RNA polymerase II C-terminal domain binding 1/386 10/18639 0.1 4.82875647668394 0.188862884733513 0.543251889391693 GO:0140135 mechanosensitive monoatomic cation channel activity 1/386 10/18639 0.1 4.82875647668394 0.188862884733513 0.543251889391693 GO:0140999 histone H3K4 trimethyltransferase activity 1/386 10/18639 0.1 4.82875647668394 0.188862884733513 0.543251889391693 GO:1905394 retromer complex binding 1/386 10/18639 0.1 4.82875647668394 0.188862884733513 0.543251889391693 GO:0016757 glycosyltransferase activity 8/386 267/18639 0.0299625468164794 1.44681841998021 0.190878659303562 0.543251889391693 GO:0043539 protein serine/threonine kinase activator activity 3/386 73/18639 0.0410958904109589 1.98442046987011 0.192555516226803 0.543251889391693 GO:0000217 DNA secondary structure binding 2/386 39/18639 0.0512820512820513 2.47628537265843 0.193138268299185 0.543251889391693 GO:0015144 carbohydrate transmembrane transporter activity 2/386 40/18639 0.05 2.41437823834197 0.200695436142759 0.543251889391693 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/386 11/18639 0.0909090909090909 4.38977861516722 0.205669955778274 0.543251889391693 GO:0002162 dystroglycan binding 1/386 11/18639 0.0909090909090909 4.38977861516722 0.205669955778274 0.543251889391693 GO:0004016 adenylate cyclase activity 1/386 11/18639 0.0909090909090909 4.38977861516722 0.205669955778274 0.543251889391693 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 1/386 11/18639 0.0909090909090909 4.38977861516722 0.205669955778274 0.543251889391693 GO:0004954 prostanoid receptor activity 1/386 11/18639 0.0909090909090909 4.38977861516722 0.205669955778274 0.543251889391693 GO:0005114 type II transforming growth factor beta receptor binding 1/386 11/18639 0.0909090909090909 4.38977861516722 0.205669955778274 0.543251889391693 GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity 1/386 11/18639 0.0909090909090909 4.38977861516722 0.205669955778274 0.543251889391693 GO:0008432 JUN kinase binding 1/386 11/18639 0.0909090909090909 4.38977861516722 0.205669955778274 0.543251889391693 GO:0019215 intermediate filament binding 1/386 11/18639 0.0909090909090909 4.38977861516722 0.205669955778274 0.543251889391693 GO:0032794 GTPase activating protein binding 1/386 11/18639 0.0909090909090909 4.38977861516722 0.205669955778274 0.543251889391693 GO:0034056 estrogen response element binding 1/386 11/18639 0.0909090909090909 4.38977861516722 0.205669955778274 0.543251889391693 GO:0035252 UDP-xylosyltransferase activity 1/386 11/18639 0.0909090909090909 4.38977861516722 0.205669955778274 0.543251889391693 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/386 11/18639 0.0909090909090909 4.38977861516722 0.205669955778274 0.543251889391693 GO:0042285 xylosyltransferase activity 1/386 11/18639 0.0909090909090909 4.38977861516722 0.205669955778274 0.543251889391693 GO:0043522 leucine zipper domain binding 1/386 11/18639 0.0909090909090909 4.38977861516722 0.205669955778274 0.543251889391693 GO:0043855 cyclic nucleotide-activated monoatomic ion channel activity 1/386 11/18639 0.0909090909090909 4.38977861516722 0.205669955778274 0.543251889391693 GO:0045294 alpha-catenin binding 1/386 11/18639 0.0909090909090909 4.38977861516722 0.205669955778274 0.543251889391693 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 1/386 11/18639 0.0909090909090909 4.38977861516722 0.205669955778274 0.543251889391693 GO:0050998 nitric-oxide synthase binding 1/386 11/18639 0.0909090909090909 4.38977861516722 0.205669955778274 0.543251889391693 GO:0070697 activin receptor binding 1/386 11/18639 0.0909090909090909 4.38977861516722 0.205669955778274 0.543251889391693 GO:0097493 structural molecule activity conferring elasticity 1/386 11/18639 0.0909090909090909 4.38977861516722 0.205669955778274 0.543251889391693 GO:1990948 ubiquitin ligase inhibitor activity 1/386 11/18639 0.0909090909090909 4.38977861516722 0.205669955778274 0.543251889391693 GO:0046906 tetrapyrrole binding 5/386 152/18639 0.0328947368421053 1.5884067357513 0.207939363818359 0.543251889391693 GO:0001727 lipid kinase activity 2/386 41/18639 0.0487804878048781 2.35549096423607 0.208286349482224 0.543251889391693 GO:0061650 ubiquitin-like protein conjugating enzyme activity 2/386 41/18639 0.0487804878048781 2.35549096423607 0.208286349482224 0.543251889391693 GO:0140297 DNA-binding transcription factor binding 13/386 488/18639 0.0266393442622951 1.2863490614117 0.214191970418264 0.543251889391693 GO:0001221 transcription coregulator binding 4/386 115/18639 0.0347826086956522 1.67956747015093 0.215655406079853 0.543251889391693 GO:0043175 RNA polymerase core enzyme binding 2/386 42/18639 0.0476190476190476 2.29940784603997 0.215906384859907 0.543251889391693 GO:0019199 transmembrane receptor protein kinase activity 3/386 78/18639 0.0384615384615385 1.85721402949382 0.219324865369783 0.543251889391693 GO:0005025 transforming growth factor beta receptor activity, type I 1/386 12/18639 0.0833333333333333 4.02396373056995 0.222129661440159 0.543251889391693 GO:0005026 transforming growth factor beta receptor activity, type II 1/386 12/18639 0.0833333333333333 4.02396373056995 0.222129661440159 0.543251889391693 GO:0005095 GTPase inhibitor activity 1/386 12/18639 0.0833333333333333 4.02396373056995 0.222129661440159 0.543251889391693 GO:0005165 neurotrophin receptor binding 1/386 12/18639 0.0833333333333333 4.02396373056995 0.222129661440159 0.543251889391693 GO:0005436 sodium:phosphate symporter activity 1/386 12/18639 0.0833333333333333 4.02396373056995 0.222129661440159 0.543251889391693 GO:0008179 adenylate cyclase binding 1/386 12/18639 0.0833333333333333 4.02396373056995 0.222129661440159 0.543251889391693 GO:0015166 polyol transmembrane transporter activity 1/386 12/18639 0.0833333333333333 4.02396373056995 0.222129661440159 0.543251889391693 GO:0015269 calcium-activated potassium channel activity 1/386 12/18639 0.0833333333333333 4.02396373056995 0.222129661440159 0.543251889391693 GO:0015368 calcium:monoatomic cation antiporter activity 1/386 12/18639 0.0833333333333333 4.02396373056995 0.222129661440159 0.543251889391693 GO:0016361 activin receptor activity, type I 1/386 12/18639 0.0833333333333333 4.02396373056995 0.222129661440159 0.543251889391693 GO:0016362 activin receptor activity, type II 1/386 12/18639 0.0833333333333333 4.02396373056995 0.222129661440159 0.543251889391693 GO:0017002 activin receptor activity 1/386 12/18639 0.0833333333333333 4.02396373056995 0.222129661440159 0.543251889391693 GO:0034452 dynactin binding 1/386 12/18639 0.0833333333333333 4.02396373056995 0.222129661440159 0.543251889391693 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/386 12/18639 0.0833333333333333 4.02396373056995 0.222129661440159 0.543251889391693 GO:0035497 cAMP response element binding 1/386 12/18639 0.0833333333333333 4.02396373056995 0.222129661440159 0.543251889391693 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/386 12/18639 0.0833333333333333 4.02396373056995 0.222129661440159 0.543251889391693 GO:0097371 MDM2/MDM4 family protein binding 1/386 12/18639 0.0833333333333333 4.02396373056995 0.222129661440159 0.543251889391693 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/386 12/18639 0.0833333333333333 4.02396373056995 0.222129661440159 0.543251889391693 GO:1990247 N6-methyladenosine-containing RNA reader activity 1/386 12/18639 0.0833333333333333 4.02396373056995 0.222129661440159 0.543251889391693 GO:0019208 phosphatase regulator activity 4/386 117/18639 0.0341880341880342 1.65085691510562 0.224410352398995 0.5468483316582 GO:0001223 transcription coactivator binding 2/386 44/18639 0.0454545454545455 2.19488930758361 0.231216203061455 0.55036136159175 GO:0030547 signaling receptor inhibitor activity 2/386 44/18639 0.0454545454545455 2.19488930758361 0.231216203061455 0.55036136159175 GO:0043014 alpha-tubulin binding 2/386 44/18639 0.0454545454545455 2.19488930758361 0.231216203061455 0.55036136159175 GO:0001618 virus receptor activity 3/386 81/18639 0.037037037037037 1.78842832469775 0.23573435216266 0.55036136159175 GO:0015079 potassium ion transmembrane transporter activity 5/386 160/18639 0.03125 1.50898639896373 0.237979639013969 0.55036136159175 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/386 13/18639 0.0769230769230769 3.71442805898764 0.238249162738495 0.55036136159175 GO:0005542 folic acid binding 1/386 13/18639 0.0769230769230769 3.71442805898764 0.238249162738495 0.55036136159175 GO:0008253 5'-nucleotidase activity 1/386 13/18639 0.0769230769230769 3.71442805898764 0.238249162738495 0.55036136159175 GO:0017154 semaphorin receptor activity 1/386 13/18639 0.0769230769230769 3.71442805898764 0.238249162738495 0.55036136159175 GO:0039706 co-receptor binding 1/386 13/18639 0.0769230769230769 3.71442805898764 0.238249162738495 0.55036136159175 GO:0046974 histone H3K9 methyltransferase activity 1/386 13/18639 0.0769230769230769 3.71442805898764 0.238249162738495 0.55036136159175 GO:0051011 microtubule minus-end binding 1/386 13/18639 0.0769230769230769 3.71442805898764 0.238249162738495 0.55036136159175 GO:0070123 transforming growth factor beta receptor activity, type III 1/386 13/18639 0.0769230769230769 3.71442805898764 0.238249162738495 0.55036136159175 GO:0071837 HMG box domain binding 1/386 13/18639 0.0769230769230769 3.71442805898764 0.238249162738495 0.55036136159175 GO:0004715 non-membrane spanning protein tyrosine kinase activity 2/386 45/18639 0.0444444444444444 2.14611398963731 0.238897598439086 0.55036136159175 GO:0008009 chemokine activity 2/386 45/18639 0.0444444444444444 2.14611398963731 0.238897598439086 0.55036136159175 GO:0140272 exogenous protein binding 3/386 82/18639 0.0365853658536585 1.76661822317705 0.24125205241683 0.55370381915145 GO:0030276 clathrin binding 2/386 46/18639 0.0434782608695652 2.09945933768867 0.246591330828566 0.55370381915145 GO:0051117 ATPase binding 3/386 84/18639 0.0357142857142857 1.72455588452998 0.252349499111233 0.55370381915145 GO:0004065 arylsulfatase activity 1/386 14/18639 0.0714285714285714 3.44911176905996 0.254035473443044 0.55370381915145 GO:0008195 phosphatidate phosphatase activity 1/386 14/18639 0.0714285714285714 3.44911176905996 0.254035473443044 0.55370381915145 GO:0008331 high voltage-gated calcium channel activity 1/386 14/18639 0.0714285714285714 3.44911176905996 0.254035473443044 0.55370381915145 GO:0008559 ABC-type xenobiotic transporter activity 1/386 14/18639 0.0714285714285714 3.44911176905996 0.254035473443044 0.55370381915145 GO:0019992 diacylglycerol binding 1/386 14/18639 0.0714285714285714 3.44911176905996 0.254035473443044 0.55370381915145 GO:0032454 histone H3K9 demethylase activity 1/386 14/18639 0.0714285714285714 3.44911176905996 0.254035473443044 0.55370381915145 GO:0042043 neurexin family protein binding 1/386 14/18639 0.0714285714285714 3.44911176905996 0.254035473443044 0.55370381915145 GO:0044548 S100 protein binding 1/386 14/18639 0.0714285714285714 3.44911176905996 0.254035473443044 0.55370381915145 GO:0071933 Arp2/3 complex binding 1/386 14/18639 0.0714285714285714 3.44911176905996 0.254035473443044 0.55370381915145 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/386 14/18639 0.0714285714285714 3.44911176905996 0.254035473443044 0.55370381915145 GO:0098821 BMP receptor activity 1/386 14/18639 0.0714285714285714 3.44911176905996 0.254035473443044 0.55370381915145 GO:1901612 cardiolipin binding 1/386 14/18639 0.0714285714285714 3.44911176905996 0.254035473443044 0.55370381915145 GO:1990825 sequence-specific mRNA binding 1/386 14/18639 0.0714285714285714 3.44911176905996 0.254035473443044 0.55370381915145 GO:0140938 histone H3 methyltransferase activity 2/386 47/18639 0.0425531914893617 2.05478999007827 0.254293605832518 0.55370381915145 GO:0005267 potassium channel activity 4/386 124/18639 0.032258064516129 1.55766337957546 0.255718720281305 0.555016515080004 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2/386 48/18639 0.0416666666666667 2.01198186528497 0.262000780135844 0.565384521458336 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/386 15/18639 0.0666666666666667 3.21917098445596 0.269495463094104 0.565384521458336 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/386 15/18639 0.0666666666666667 3.21917098445596 0.269495463094104 0.565384521458336 GO:0004953 icosanoid receptor activity 1/386 15/18639 0.0666666666666667 3.21917098445596 0.269495463094104 0.565384521458336 GO:0005523 tropomyosin binding 1/386 15/18639 0.0666666666666667 3.21917098445596 0.269495463094104 0.565384521458336 GO:0008252 nucleotidase activity 1/386 15/18639 0.0666666666666667 3.21917098445596 0.269495463094104 0.565384521458336 GO:0015250 water channel activity 1/386 15/18639 0.0666666666666667 3.21917098445596 0.269495463094104 0.565384521458336 GO:0045504 dynein heavy chain binding 1/386 15/18639 0.0666666666666667 3.21917098445596 0.269495463094104 0.565384521458336 GO:0055105 ubiquitin-protein transferase inhibitor activity 1/386 15/18639 0.0666666666666667 3.21917098445596 0.269495463094104 0.565384521458336 GO:0001222 transcription corepressor binding 2/386 49/18639 0.0408163265306122 1.9709210108914 0.269709356903088 0.565384521458336 GO:0035254 glutamate receptor binding 2/386 49/18639 0.0408163265306122 1.9709210108914 0.269709356903088 0.565384521458336 GO:0016651 oxidoreductase activity, acting on NAD(P)H 3/386 88/18639 0.0340909090909091 1.64616698068771 0.274748616678765 0.574165065814757 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/386 16/18639 0.0625 3.01797279792746 0.284635859960818 0.586750821328743 GO:0004708 MAP kinase kinase activity 1/386 16/18639 0.0625 3.01797279792746 0.284635859960818 0.586750821328743 GO:0030275 LRR domain binding 1/386 16/18639 0.0625 3.01797279792746 0.284635859960818 0.586750821328743 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/386 16/18639 0.0625 3.01797279792746 0.284635859960818 0.586750821328743 GO:0005048 signal sequence binding 2/386 51/18639 0.0392156862745098 1.89362999085645 0.285117436141967 0.586750821328743 GO:0031072 heat shock protein binding 4/386 131/18639 0.0305343511450382 1.47442945852945 0.287838090314047 0.590549273440674 GO:0030159 signaling receptor complex adaptor activity 2/386 52/18639 0.0384615384615385 1.85721402949382 0.292810637648667 0.596276390586444 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/386 17/18639 0.0588235294117647 2.84044498628467 0.299463253938969 0.596276390586444 GO:0005092 GDP-dissociation inhibitor activity 1/386 17/18639 0.0588235294117647 2.84044498628467 0.299463253938969 0.596276390586444 GO:0008429 phosphatidylethanolamine binding 1/386 17/18639 0.0588235294117647 2.84044498628467 0.299463253938969 0.596276390586444 GO:0008484 sulfuric ester hydrolase activity 1/386 17/18639 0.0588235294117647 2.84044498628467 0.299463253938969 0.596276390586444 GO:0016805 dipeptidase activity 1/386 17/18639 0.0588235294117647 2.84044498628467 0.299463253938969 0.596276390586444 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/386 17/18639 0.0588235294117647 2.84044498628467 0.299463253938969 0.596276390586444 GO:0031489 myosin V binding 1/386 17/18639 0.0588235294117647 2.84044498628467 0.299463253938969 0.596276390586444 GO:0032183 SUMO binding 1/386 17/18639 0.0588235294117647 2.84044498628467 0.299463253938969 0.596276390586444 GO:0070492 oligosaccharide binding 1/386 17/18639 0.0588235294117647 2.84044498628467 0.299463253938969 0.596276390586444 GO:0051087 protein-folding chaperone binding 4/386 134/18639 0.0298507462686567 1.44141984378625 0.301780636583048 0.598039792000705 GO:0051213 dioxygenase activity 3/386 93/18639 0.032258064516129 1.55766337957546 0.303006827947024 0.598039792000705 GO:0051219 phosphoprotein binding 3/386 93/18639 0.032258064516129 1.55766337957546 0.303006827947024 0.598039792000705 GO:0042562 hormone binding 3/386 94/18639 0.0319148936170213 1.5410924925587 0.308678803897239 0.600394524328342 GO:0140789 histone phosphatase activity 4/386 136/18639 0.0294117647058824 1.42022249314233 0.311118559969271 0.600394524328342 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/386 18/18639 0.0555555555555556 2.68264248704663 0.313984099389488 0.600394524328342 GO:0005372 water transmembrane transporter activity 1/386 18/18639 0.0555555555555556 2.68264248704663 0.313984099389488 0.600394524328342 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/386 18/18639 0.0555555555555556 2.68264248704663 0.313984099389488 0.600394524328342 GO:0017128 phospholipid scramblase activity 1/386 18/18639 0.0555555555555556 2.68264248704663 0.313984099389488 0.600394524328342 GO:0031690 adrenergic receptor binding 1/386 18/18639 0.0555555555555556 2.68264248704663 0.313984099389488 0.600394524328342 GO:0035615 clathrin adaptor activity 1/386 18/18639 0.0555555555555556 2.68264248704663 0.313984099389488 0.600394524328342 GO:0050811 GABA receptor binding 1/386 18/18639 0.0555555555555556 2.68264248704663 0.313984099389488 0.600394524328342 GO:0070628 proteasome binding 1/386 18/18639 0.0555555555555556 2.68264248704663 0.313984099389488 0.600394524328342 GO:1901611 phosphatidylglycerol binding 1/386 18/18639 0.0555555555555556 2.68264248704663 0.313984099389488 0.600394524328342 GO:0030295 protein kinase activator activity 4/386 139/18639 0.0287769784172662 1.38957020911768 0.325174203024352 0.613679181704263 GO:0005229 intracellularly calcium-gated chloride channel activity 1/386 19/18639 0.0526315789473684 2.54145077720207 0.328204717918872 0.613679181704263 GO:0008381 mechanosensitive monoatomic ion channel activity 1/386 19/18639 0.0526315789473684 2.54145077720207 0.328204717918872 0.613679181704263 GO:0042577 lipid phosphatase activity 1/386 19/18639 0.0526315789473684 2.54145077720207 0.328204717918872 0.613679181704263 GO:0043395 heparan sulfate proteoglycan binding 1/386 19/18639 0.0526315789473684 2.54145077720207 0.328204717918872 0.613679181704263 GO:0046624 sphingolipid transporter activity 1/386 19/18639 0.0526315789473684 2.54145077720207 0.328204717918872 0.613679181704263 GO:0141147 intracellularly calcium-gated channel activity 1/386 19/18639 0.0526315789473684 2.54145077720207 0.328204717918872 0.613679181704263 GO:1990380 K48-linked deubiquitinase activity 1/386 19/18639 0.0526315789473684 2.54145077720207 0.328204717918872 0.613679181704263 GO:0000287 magnesium ion binding 6/386 230/18639 0.0260869565217391 1.2596756026132 0.341829856081488 0.627550620229181 GO:0000339 RNA cap binding 1/386 20/18639 0.05 2.41437823834197 0.342131301102724 0.627550620229181 GO:0015095 magnesium ion transmembrane transporter activity 1/386 20/18639 0.05 2.41437823834197 0.342131301102724 0.627550620229181 GO:0016004 phospholipase activator activity 1/386 20/18639 0.05 2.41437823834197 0.342131301102724 0.627550620229181 GO:0030742 GTP-dependent protein binding 1/386 20/18639 0.05 2.41437823834197 0.342131301102724 0.627550620229181 GO:0031418 L-ascorbic acid binding 1/386 20/18639 0.05 2.41437823834197 0.342131301102724 0.627550620229181 GO:0140939 histone H4 methyltransferase activity 1/386 20/18639 0.05 2.41437823834197 0.342131301102724 0.627550620229181 GO:1901681 sulfur compound binding 7/386 275/18639 0.0254545454545455 1.22913801224682 0.343933333400789 0.628183815552483 GO:0001786 phosphatidylserine binding 2/386 59/18639 0.0338983050847458 1.63686660226574 0.346199080571146 0.628183815552483 GO:0070063 RNA polymerase binding 2/386 59/18639 0.0338983050847458 1.63686660226574 0.346199080571146 0.628183815552483 GO:0070888 E-box binding 2/386 59/18639 0.0338983050847458 1.63686660226574 0.346199080571146 0.628183815552483 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 2/386 60/18639 0.0333333333333333 1.60958549222798 0.35372993928041 0.634952245221183 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/386 21/18639 0.0476190476190476 2.29940784603997 0.355769913153551 0.634952245221183 GO:0008373 sialyltransferase activity 1/386 21/18639 0.0476190476190476 2.29940784603997 0.355769913153551 0.634952245221183 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/386 21/18639 0.0476190476190476 2.29940784603997 0.355769913153551 0.634952245221183 GO:0010314 phosphatidylinositol-5-phosphate binding 1/386 21/18639 0.0476190476190476 2.29940784603997 0.355769913153551 0.634952245221183 GO:0140312 cargo adaptor activity 1/386 21/18639 0.0476190476190476 2.29940784603997 0.355769913153551 0.634952245221183 GO:0046982 protein heterodimerization activity 9/386 369/18639 0.024390243902439 1.17774548211803 0.356513927316782 0.634952245221183 GO:0015026 coreceptor activity 2/386 61/18639 0.0327868852459016 1.58319884481441 0.36123014997291 0.641658819030827 GO:0019209 kinase activator activity 4/386 148/18639 0.027027027027027 1.30506931802269 0.367504897784714 0.645493220558116 GO:0005243 gap junction channel activity 1/386 22/18639 0.0454545454545455 2.19488930758361 0.369126493533974 0.645493220558116 GO:0015377 chloride:monoatomic cation symporter activity 1/386 22/18639 0.0454545454545455 2.19488930758361 0.369126493533974 0.645493220558116 GO:0016881 acid-amino acid ligase activity 1/386 22/18639 0.0454545454545455 2.19488930758361 0.369126493533974 0.645493220558116 GO:0050321 tau-protein kinase activity 1/386 22/18639 0.0454545454545455 2.19488930758361 0.369126493533974 0.645493220558116 GO:0140517 protein-RNA adaptor activity 1/386 22/18639 0.0454545454545455 2.19488930758361 0.369126493533974 0.645493220558116 GO:0005507 copper ion binding 2/386 63/18639 0.0317460317460317 1.53293856402665 0.376130886453516 0.656042243814272 GO:0042171 lysophosphatidic acid acyltransferase activity 1/386 23/18639 0.0434782608695652 2.09945933768867 0.382206859516457 0.658136811667369 GO:0043274 phospholipase binding 1/386 23/18639 0.0434782608695652 2.09945933768867 0.382206859516457 0.658136811667369 GO:0070577 lysine-acetylated histone binding 1/386 23/18639 0.0434782608695652 2.09945933768867 0.382206859516457 0.658136811667369 GO:0071617 lysophospholipid acyltransferase activity 1/386 23/18639 0.0434782608695652 2.09945933768867 0.382206859516457 0.658136811667369 GO:0099186 structural constituent of postsynapse 1/386 23/18639 0.0434782608695652 2.09945933768867 0.382206859516457 0.658136811667369 GO:0016758 hexosyltransferase activity 5/386 197/18639 0.0253807106598985 1.22557270981826 0.38695165097068 0.663274324293991 GO:0005315 phosphate transmembrane transporter activity 1/386 24/18639 0.0416666666666667 2.01198186528497 0.395016708690643 0.663274324293991 GO:0015149 hexose transmembrane transporter activity 1/386 24/18639 0.0416666666666667 2.01198186528497 0.395016708690643 0.663274324293991 GO:0030215 semaphorin receptor binding 1/386 24/18639 0.0416666666666667 2.01198186528497 0.395016708690643 0.663274324293991 GO:0030552 cAMP binding 1/386 24/18639 0.0416666666666667 2.01198186528497 0.395016708690643 0.663274324293991 GO:0055056 D-glucose transmembrane transporter activity 1/386 24/18639 0.0416666666666667 2.01198186528497 0.395016708690643 0.663274324293991 GO:0060229 lipase activator activity 1/386 24/18639 0.0416666666666667 2.01198186528497 0.395016708690643 0.663274324293991 GO:0070300 phosphatidic acid binding 1/386 24/18639 0.0416666666666667 2.01198186528497 0.395016708690643 0.663274324293991 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/386 24/18639 0.0416666666666667 2.01198186528497 0.395016708690643 0.663274324293991 GO:0140033 acetylation-dependent protein binding 1/386 24/18639 0.0416666666666667 2.01198186528497 0.395016708690643 0.663274324293991 GO:0042054 histone methyltransferase activity 2/386 67/18639 0.0298507462686567 1.44141984378625 0.405484520713357 0.67593143601494 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/386 25/18639 0.04 1.93150259067358 0.407561621419379 0.67593143601494 GO:0019211 phosphatase activator activity 1/386 25/18639 0.04 1.93150259067358 0.407561621419379 0.67593143601494 GO:0042974 nuclear retinoic acid receptor binding 1/386 25/18639 0.04 1.93150259067358 0.407561621419379 0.67593143601494 GO:0120020 cholesterol transfer activity 1/386 25/18639 0.04 1.93150259067358 0.407561621419379 0.67593143601494 GO:0003714 transcription corepressor activity 5/386 204/18639 0.0245098039215686 1.18351874428528 0.415641672373491 0.681348284020543 GO:0005227 calcium-activated cation channel activity 1/386 26/18639 0.0384615384615385 1.85721402949382 0.419847063244463 0.681348284020543 GO:0015145 monosaccharide transmembrane transporter activity 1/386 26/18639 0.0384615384615385 1.85721402949382 0.419847063244463 0.681348284020543 GO:0034237 protein kinase A regulatory subunit binding 1/386 26/18639 0.0384615384615385 1.85721402949382 0.419847063244463 0.681348284020543 GO:0043548 phosphatidylinositol 3-kinase binding 1/386 26/18639 0.0384615384615385 1.85721402949382 0.419847063244463 0.681348284020543 GO:0050681 nuclear androgen receptor binding 1/386 26/18639 0.0384615384615385 1.85721402949382 0.419847063244463 0.681348284020543 GO:0070006 metalloaminopeptidase activity 1/386 26/18639 0.0384615384615385 1.85721402949382 0.419847063244463 0.681348284020543 GO:0070412 R-SMAD binding 1/386 26/18639 0.0384615384615385 1.85721402949382 0.419847063244463 0.681348284020543 GO:0016279 protein-lysine N-methyltransferase activity 2/386 69/18639 0.0289855072463768 1.39963955845911 0.419912423929698 0.681348284020543 GO:0016278 lysine N-methyltransferase activity 2/386 70/18639 0.0285714285714286 1.37964470762398 0.427059306115905 0.689167639217799 GO:0016782 transferase activity, transferring sulphur-containing groups 2/386 70/18639 0.0285714285714286 1.37964470762398 0.427059306115905 0.689167639217799 GO:0001671 ATPase activator activity 1/386 27/18639 0.037037037037037 1.78842832469775 0.431878387243154 0.689167639217799 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/386 27/18639 0.037037037037037 1.78842832469775 0.431878387243154 0.689167639217799 GO:0008266 poly(U) RNA binding 1/386 27/18639 0.037037037037037 1.78842832469775 0.431878387243154 0.689167639217799 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/386 27/18639 0.037037037037037 1.78842832469775 0.431878387243154 0.689167639217799 GO:0035255 ionotropic glutamate receptor binding 1/386 27/18639 0.037037037037037 1.78842832469775 0.431878387243154 0.689167639217799 GO:0019789 SUMO transferase activity 1/386 28/18639 0.0357142857142857 1.72455588452998 0.443660836336435 0.698067749480405 GO:0045499 chemorepellent activity 1/386 28/18639 0.0357142857142857 1.72455588452998 0.443660836336435 0.698067749480405 GO:0050698 proteoglycan sulfotransferase activity 1/386 28/18639 0.0357142857142857 1.72455588452998 0.443660836336435 0.698067749480405 GO:0051119 sugar transmembrane transporter activity 1/386 28/18639 0.0357142857142857 1.72455588452998 0.443660836336435 0.698067749480405 GO:0097718 disordered domain specific binding 1/386 28/18639 0.0357142857142857 1.72455588452998 0.443660836336435 0.698067749480405 GO:0141052 histone H3 demethylase activity 1/386 28/18639 0.0357142857142857 1.72455588452998 0.443660836336435 0.698067749480405 GO:0003684 damaged DNA binding 2/386 74/18639 0.027027027027027 1.30506931802269 0.455172109975617 0.709205388186142 GO:0035250 UDP-galactosyltransferase activity 1/386 29/18639 0.0344827586206897 1.66508844023584 0.455199545550026 0.709205388186142 GO:0051861 glycolipid binding 1/386 29/18639 0.0344827586206897 1.66508844023584 0.455199545550026 0.709205388186142 GO:0046873 metal ion transmembrane transporter activity 10/386 450/18639 0.0222222222222222 1.07305699481865 0.455481330536029 0.709205388186142 GO:0003725 double-stranded RNA binding 2/386 75/18639 0.0266666666666667 1.28766839378238 0.46207638779125 0.709205388186142 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 1/386 30/18639 0.0333333333333333 1.60958549222798 0.466499544229107 0.709205388186142 GO:0008187 poly-pyrimidine tract binding 1/386 30/18639 0.0333333333333333 1.60958549222798 0.466499544229107 0.709205388186142 GO:0022839 monoatomic ion-gated channel activity 1/386 30/18639 0.0333333333333333 1.60958549222798 0.466499544229107 0.709205388186142 GO:0031210 phosphatidylcholine binding 1/386 30/18639 0.0333333333333333 1.60958549222798 0.466499544229107 0.709205388186142 GO:0032452 histone demethylase activity 1/386 30/18639 0.0333333333333333 1.60958549222798 0.466499544229107 0.709205388186142 GO:0033612 receptor serine/threonine kinase binding 1/386 30/18639 0.0333333333333333 1.60958549222798 0.466499544229107 0.709205388186142 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/386 30/18639 0.0333333333333333 1.60958549222798 0.466499544229107 0.709205388186142 GO:0051721 protein phosphatase 2A binding 1/386 30/18639 0.0333333333333333 1.60958549222798 0.466499544229107 0.709205388186142 GO:0070566 adenylyltransferase activity 1/386 30/18639 0.0333333333333333 1.60958549222798 0.466499544229107 0.709205388186142 GO:0098918 structural constituent of synapse 1/386 30/18639 0.0333333333333333 1.60958549222798 0.466499544229107 0.709205388186142 GO:0005164 tumor necrosis factor receptor binding 1/386 31/18639 0.032258064516129 1.55766337957546 0.477565758207696 0.719546622299541 GO:0016411 acylglycerol O-acyltransferase activity 1/386 31/18639 0.032258064516129 1.55766337957546 0.477565758207696 0.719546622299541 GO:0070273 phosphatidylinositol-4-phosphate binding 1/386 31/18639 0.032258064516129 1.55766337957546 0.477565758207696 0.719546622299541 GO:0140457 protein demethylase activity 1/386 31/18639 0.032258064516129 1.55766337957546 0.477565758207696 0.719546622299541 GO:0140030 modification-dependent protein binding 4/386 173/18639 0.023121387283237 1.11647548593848 0.482966415658065 0.724886617718941 GO:0008378 galactosyltransferase activity 1/386 32/18639 0.03125 1.50898639896373 0.488403011933611 0.724886617718941 GO:0042910 xenobiotic transmembrane transporter activity 1/386 32/18639 0.03125 1.50898639896373 0.488403011933611 0.724886617718941 GO:0043425 bHLH transcription factor binding 1/386 32/18639 0.03125 1.50898639896373 0.488403011933611 0.724886617718941 GO:0070717 poly-purine tract binding 1/386 32/18639 0.03125 1.50898639896373 0.488403011933611 0.724886617718941 GO:0120015 sterol transfer activity 1/386 32/18639 0.03125 1.50898639896373 0.488403011933611 0.724886617718941 GO:0022836 gated channel activity 7/386 318/18639 0.0220125786163522 1.06293381562225 0.488627275647582 0.724886617718941 GO:0048306 calcium-dependent protein binding 2/386 80/18639 0.025 1.20718911917098 0.495810259571121 0.730663385295433 GO:0016887 ATP hydrolysis activity 9/386 417/18639 0.0215827338129496 1.04217765683826 0.497347617825075 0.730663385295433 GO:0019956 chemokine binding 1/386 33/18639 0.0303030303030303 1.46325953838907 0.499016030549918 0.730663385295433 GO:0030296 protein tyrosine kinase activator activity 1/386 33/18639 0.0303030303030303 1.46325953838907 0.499016030549918 0.730663385295433 GO:0140311 protein sequestering activity 1/386 33/18639 0.0303030303030303 1.46325953838907 0.499016030549918 0.730663385295433 GO:0140416 transcription regulator inhibitor activity 1/386 33/18639 0.0303030303030303 1.46325953838907 0.499016030549918 0.730663385295433 GO:0030971 receptor tyrosine kinase binding 2/386 81/18639 0.0246913580246914 1.1922855497985 0.502394459758677 0.734017879517547 GO:0005319 lipid transporter activity 4/386 178/18639 0.0224719101123595 1.08511381498515 0.505151434467738 0.736451875303937 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/386 34/18639 0.0294117647058824 1.42022249314233 0.509409441933758 0.7394653189361 GO:0090482 vitamin transmembrane transporter activity 1/386 34/18639 0.0294117647058824 1.42022249314233 0.509409441933758 0.7394653189361 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 4/386 181/18639 0.0220994475138122 1.06712850313457 0.518259176556429 0.749405450038591 GO:0005154 epidermal growth factor receptor binding 1/386 35/18639 0.0285714285714286 1.37964470762398 0.519587778693423 0.749405450038591 GO:0140566 histone reader activity 1/386 35/18639 0.0285714285714286 1.37964470762398 0.519587778693423 0.749405450038591 GO:0030246 carbohydrate binding 6/386 280/18639 0.0214285714285714 1.03473353071799 0.523823556086608 0.7539038387174 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/386 36/18639 0.0277777777777778 1.34132124352332 0.529555480124531 0.760531806561827 GO:0050660 flavin adenine dinucleotide binding 2/386 86/18639 0.0232558139534884 1.12296662248464 0.534471055055875 0.765961703105553 GO:0002020 protease binding 3/386 136/18639 0.0220588235294118 1.06516686985675 0.537187550559449 0.768223721668703 GO:0022829 wide pore channel activity 1/386 37/18639 0.027027027027027 1.30506931802269 0.539316894126141 0.769638273858657 GO:0016922 nuclear receptor binding 3/386 137/18639 0.0218978102189781 1.05739192920086 0.542144032133829 0.772040552089313 GO:0005109 frizzled binding 1/386 38/18639 0.0263157894736842 1.27072538860104 0.548876279077614 0.779982080794504 GO:0005261 monoatomic cation channel activity 7/386 341/18639 0.0205278592375367 0.991240332457113 0.562543528736991 0.791319735848903 GO:0004177 aminopeptidase activity 1/386 40/18639 0.025 1.20718911917098 0.567405558742028 0.791319735848903 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/386 40/18639 0.025 1.20718911917098 0.567405558742028 0.791319735848903 GO:0030331 nuclear estrogen receptor binding 1/386 40/18639 0.025 1.20718911917098 0.567405558742028 0.791319735848903 GO:0032451 demethylase activity 1/386 40/18639 0.025 1.20718911917098 0.567405558742028 0.791319735848903 GO:0050997 quaternary ammonium group binding 1/386 40/18639 0.025 1.20718911917098 0.567405558742028 0.791319735848903 GO:0061791 GTPase motor activity 1/386 40/18639 0.025 1.20718911917098 0.567405558742028 0.791319735848903 GO:0071949 FAD binding 1/386 40/18639 0.025 1.20718911917098 0.567405558742028 0.791319735848903 GO:1990606 membrane scission GTPase motor activity 1/386 40/18639 0.025 1.20718911917098 0.567405558742028 0.791319735848903 GO:0022843 voltage-gated monoatomic cation channel activity 3/386 143/18639 0.020979020979021 1.01302583426936 0.571227019889619 0.795006677165965 GO:0001530 lipopolysaccharide binding 1/386 41/18639 0.024390243902439 1.17774548211803 0.576383538973523 0.797251821326082 GO:0008137 NADH dehydrogenase (ubiquinone) activity 1/386 41/18639 0.024390243902439 1.17774548211803 0.576383538973523 0.797251821326082 GO:0140828 metal cation:monoatomic cation antiporter activity 1/386 41/18639 0.024390243902439 1.17774548211803 0.576383538973523 0.797251821326082 GO:0005216 monoatomic ion channel activity 9/386 448/18639 0.0200892857142857 0.970062685048113 0.584013592999187 0.80446756346525 GO:0019894 kinesin binding 1/386 42/18639 0.0238095238095238 1.14970392301999 0.585175664683611 0.80446756346525 GO:0048487 beta-tubulin binding 1/386 42/18639 0.0238095238095238 1.14970392301999 0.585175664683611 0.80446756346525 GO:0008276 protein methyltransferase activity 2/386 95/18639 0.0210526315789474 1.01658031088083 0.588549965299012 0.804830114667244 GO:0015085 calcium ion transmembrane transporter activity 3/386 147/18639 0.0204081632653061 0.985460505445702 0.589969793078269 0.804830114667244 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/386 43/18639 0.0232558139534884 1.12296662248464 0.593785773487834 0.804830114667244 GO:0005245 voltage-gated calcium channel activity 1/386 43/18639 0.0232558139534884 1.12296662248464 0.593785773487834 0.804830114667244 GO:0008200 ion channel inhibitor activity 1/386 43/18639 0.0232558139534884 1.12296662248464 0.593785773487834 0.804830114667244 GO:0008375 acetylglucosaminyltransferase activity 1/386 43/18639 0.0232558139534884 1.12296662248464 0.593785773487834 0.804830114667244 GO:0048156 tau protein binding 1/386 43/18639 0.0232558139534884 1.12296662248464 0.593785773487834 0.804830114667244 GO:0001046 core promoter sequence-specific DNA binding 1/386 44/18639 0.0227272727272727 1.0974446537918 0.602217623962866 0.81137105024937 GO:0003954 NADH dehydrogenase activity 1/386 44/18639 0.0227272727272727 1.0974446537918 0.602217623962866 0.81137105024937 GO:0016248 channel inhibitor activity 1/386 44/18639 0.0227272727272727 1.0974446537918 0.602217623962866 0.81137105024937 GO:0005249 voltage-gated potassium channel activity 2/386 98/18639 0.0204081632653061 0.985460505445702 0.605511139986639 0.812564651075509 GO:0008170 N-methyltransferase activity 2/386 98/18639 0.0204081632653061 0.985460505445702 0.605511139986639 0.812564651075509 GO:0042605 peptide antigen binding 1/386 45/18639 0.0222222222222222 1.07305699481865 0.610474897270225 0.814368687069964 GO:0051539 4 iron, 4 sulfur cluster binding 1/386 45/18639 0.0222222222222222 1.07305699481865 0.610474897270225 0.814368687069964 GO:0141110 transporter inhibitor activity 1/386 45/18639 0.0222222222222222 1.07305699481865 0.610474897270225 0.814368687069964 GO:0003713 transcription coactivator activity 5/386 256/18639 0.01953125 0.943116499352332 0.614444509942418 0.81804742447955 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/386 46/18639 0.0217391304347826 1.04972966884433 0.618561198746706 0.82029235590182 GO:0030291 protein serine/threonine kinase inhibitor activity 1/386 46/18639 0.0217391304347826 1.04972966884433 0.618561198746706 0.82029235590182 GO:0005504 fatty acid binding 1/386 47/18639 0.0212765957446809 1.02739499503914 0.626480059462232 0.820589639673241 GO:0043495 protein-membrane adaptor activity 1/386 47/18639 0.0212765957446809 1.02739499503914 0.626480059462232 0.820589639673241 GO:0061749 forked DNA-dependent helicase activity 1/386 47/18639 0.0212765957446809 1.02739499503914 0.626480059462232 0.820589639673241 GO:0099095 ligand-gated monoatomic anion channel activity 1/386 47/18639 0.0212765957446809 1.02739499503914 0.626480059462232 0.820589639673241 GO:0140359 ABC-type transporter activity 1/386 47/18639 0.0212765957446809 1.02739499503914 0.626480059462232 0.820589639673241 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/386 47/18639 0.0212765957446809 1.02739499503914 0.626480059462232 0.820589639673241 GO:0008238 exopeptidase activity 2/386 102/18639 0.0196078431372549 0.946814995428223 0.627295191216878 0.820589639673241 GO:0009378 four-way junction helicase activity 1/386 48/18639 0.0208333333333333 1.00599093264249 0.634234937745772 0.823285736496915 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/386 48/18639 0.0208333333333333 1.00599093264249 0.634234937745772 0.823285736496915 GO:0036121 double-stranded DNA helicase activity 1/386 48/18639 0.0208333333333333 1.00599093264249 0.634234937745772 0.823285736496915 GO:0043138 3'-5' DNA helicase activity 1/386 48/18639 0.0208333333333333 1.00599093264249 0.634234937745772 0.823285736496915 GO:0016763 pentosyltransferase activity 1/386 49/18639 0.0204081632653061 0.985460505445702 0.641829220679994 0.831544575737037 GO:0004866 endopeptidase inhibitor activity 3/386 161/18639 0.0186335403726708 0.899768287580858 0.651299333046931 0.842197413422756 GO:0019888 protein phosphatase regulator activity 2/386 107/18639 0.0186915887850467 0.902571304053072 0.653198739697697 0.843038526378481 GO:0005021 vascular endothelial growth factor receptor activity 1/386 51/18639 0.0196078431372549 0.946814995428223 0.65654920135375 0.844134687454821 GO:0005030 neurotrophin receptor activity 1/386 51/18639 0.0196078431372549 0.946814995428223 0.65654920135375 0.844134687454821 GO:0005496 steroid binding 2/386 108/18639 0.0185185185185185 0.894214162348877 0.658204218582894 0.844653702554093 GO:0004620 phospholipase activity 2/386 109/18639 0.018348623853211 0.886010362694301 0.66315178456382 0.847061912108669 GO:0005080 protein kinase C binding 1/386 52/18639 0.0192307692307692 0.928607014746911 0.663681330053849 0.847061912108669 GO:0015103 inorganic anion transmembrane transporter activity 3/386 165/18639 0.0181818181818182 0.877955723033443 0.667572797343078 0.847061912108669 GO:0008146 sulfotransferase activity 1/386 53/18639 0.0188679245283019 0.911086127676215 0.670665728106209 0.847061912108669 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/386 53/18639 0.0188679245283019 0.911086127676215 0.670665728106209 0.847061912108669 GO:0017046 peptide hormone binding 1/386 53/18639 0.0188679245283019 0.911086127676215 0.670665728106209 0.847061912108669 GO:0038064 collagen receptor activity 1/386 53/18639 0.0188679245283019 0.911086127676215 0.670665728106209 0.847061912108669 GO:0051018 protein kinase A binding 1/386 53/18639 0.0188679245283019 0.911086127676215 0.670665728106209 0.847061912108669 GO:0003925 G protein activity 1/386 54/18639 0.0185185185185185 0.894214162348877 0.67750544773125 0.847061912108669 GO:0015485 cholesterol binding 1/386 54/18639 0.0185185185185185 0.894214162348877 0.67750544773125 0.847061912108669 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 1/386 54/18639 0.0185185185185185 0.894214162348877 0.67750544773125 0.847061912108669 GO:0051287 NAD binding 1/386 54/18639 0.0185185185185185 0.894214162348877 0.67750544773125 0.847061912108669 GO:0140463 chromatin-protein adaptor activity 1/386 54/18639 0.0185185185185185 0.894214162348877 0.67750544773125 0.847061912108669 GO:0043022 ribosome binding 2/386 112/18639 0.0178571428571429 0.862277942264989 0.677649529686935 0.847061912108669 GO:0030414 peptidase inhibitor activity 3/386 169/18639 0.0177514792899408 0.857175705920226 0.68328638370714 0.850529185668871 GO:0008374 O-acyltransferase activity 1/386 55/18639 0.0181818181818182 0.877955723033443 0.68420347824918 0.850529185668871 GO:0140313 molecular sequestering activity 1/386 55/18639 0.0181818181818182 0.877955723033443 0.68420347824918 0.850529185668871 GO:0035401 histone H3Y41 kinase activity 2/386 115/18639 0.0173913043478261 0.839783735075467 0.691635728302508 0.856613057989345 GO:0140801 histone H2AXY142 kinase activity 2/386 115/18639 0.0173913043478261 0.839783735075467 0.691635728302508 0.856613057989345 GO:0009055 electron transfer activity 2/386 116/18639 0.0172413793103448 0.83254422011792 0.696185542611214 0.858739497567107 GO:0015294 solute:monoatomic cation symporter activity 2/386 116/18639 0.0172413793103448 0.83254422011792 0.696185542611214 0.858739497567107 GO:0004601 peroxidase activity 1/386 57/18639 0.0175438596491228 0.847150259067358 0.697186122474587 0.858739497567107 GO:0005244 voltage-gated monoatomic ion channel activity 3/386 173/18639 0.0173410404624277 0.837356614453862 0.698441458021247 0.858739497567107 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 1/386 58/18639 0.0172413793103448 0.83254422011792 0.703476411825831 0.861790522654149 GO:0017116 single-stranded DNA helicase activity 1/386 58/18639 0.0172413793103448 0.83254422011792 0.703476411825831 0.861790522654149 GO:0022832 voltage-gated channel activity 3/386 175/18639 0.0171428571428571 0.827786824574389 0.705810542562958 0.863083543894921 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 1/386 59/18639 0.0169491525423729 0.818433301132871 0.709636365812981 0.866192670748213 GO:0032182 ubiquitin-like protein binding 2/386 120/18639 0.0166666666666667 0.80479274611399 0.713832499574307 0.869741763921764 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/386 60/18639 0.0166666666666667 0.80479274611399 0.715668678127092 0.870238542732574 GO:0003697 single-stranded DNA binding 2/386 121/18639 0.0165289256198347 0.798141566394039 0.718107953040064 0.870238542732574 GO:0015108 chloride transmembrane transporter activity 2/386 121/18639 0.0165289256198347 0.798141566394039 0.718107953040064 0.870238542732574 GO:0015179 L-amino acid transmembrane transporter activity 1/386 62/18639 0.0161290322580645 0.778831689787732 0.727360875994424 0.87987202741261 GO:1901682 sulfur compound transmembrane transporter activity 1/386 63/18639 0.0158730158730159 0.766469282013323 0.733025875825729 0.885138579932678 GO:0004175 endopeptidase activity 7/386 405/18639 0.0172839506172839 0.834599884858952 0.737237889666208 0.887092214565754 GO:0061135 endopeptidase regulator activity 3/386 184/18639 0.016304347826087 0.787297251633251 0.73727219610576 0.887092214565754 GO:0001664 G protein-coupled receptor binding 5/386 297/18639 0.0168350168350168 0.812921965771707 0.739650377147999 0.887965947761571 GO:0042826 histone deacetylase binding 2/386 127/18639 0.015748031496063 0.760434090816368 0.742645311547051 0.887965947761571 GO:0015276 ligand-gated monoatomic ion channel activity 3/386 186/18639 0.0161290322580645 0.778831689787732 0.743891267956776 0.887965947761571 GO:0120013 lipid transfer activity 1/386 65/18639 0.0153846153846154 0.742885611797529 0.744006070008626 0.887965947761571 GO:0031406 carboxylic acid binding 3/386 187/18639 0.0160427807486631 0.774666814441273 0.747150790618883 0.887965947761571 GO:0008235 metalloexopeptidase activity 1/386 66/18639 0.0151515151515152 0.731629769194536 0.749326068769079 0.887965947761571 GO:0022834 ligand-gated channel activity 3/386 188/18639 0.0159574468085106 0.770546246279352 0.750377163472792 0.887965947761571 GO:0031625 ubiquitin protein ligase binding 5/386 302/18639 0.0165562913907285 0.799462992828467 0.752665390619381 0.887965947761571 GO:0043177 organic acid binding 3/386 189/18639 0.0158730158730159 0.766469282013323 0.753570536355281 0.887965947761571 GO:0016298 lipase activity 2/386 130/18639 0.0153846153846154 0.742885611797529 0.754215236417182 0.887965947761571 GO:0005262 calcium channel activity 2/386 131/18639 0.0152671755725191 0.737214729264723 0.757971164350627 0.887965947761571 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 1/386 68/18639 0.0147058823529412 0.710111246571167 0.759637511430384 0.887965947761571 GO:0030145 manganese ion binding 1/386 68/18639 0.0147058823529412 0.710111246571167 0.759637511430384 0.887965947761571 GO:0032934 sterol binding 1/386 68/18639 0.0147058823529412 0.710111246571167 0.759637511430384 0.887965947761571 GO:0140223 general transcription initiation factor activity 1/386 68/18639 0.0147058823529412 0.710111246571167 0.759637511430384 0.887965947761571 GO:1990841 promoter-specific chromatin binding 1/386 68/18639 0.0147058823529412 0.710111246571167 0.759637511430384 0.887965947761571 GO:0042277 peptide binding 4/386 249/18639 0.0160642570281124 0.775703851676135 0.761140343797408 0.887965947761571 GO:0005179 hormone activity 2/386 132/18639 0.0151515151515152 0.731629769194536 0.761677457413258 0.887965947761571 GO:0140299 molecular sensor activity 1/386 71/18639 0.0140845070422535 0.680106546011822 0.774316790884168 0.901144541115195 GO:0099094 ligand-gated monoatomic cation channel activity 2/386 136/18639 0.0147058823529412 0.710111246571167 0.776015098920806 0.901566595131746 GO:0016829 lyase activity 3/386 200/18639 0.015 0.724313471502591 0.786566436674957 0.909348191771795 GO:0003678 DNA helicase activity 1/386 74/18639 0.0135135135135135 0.652534659011343 0.788101766202223 0.909348191771795 GO:0035064 methylated histone binding 1/386 74/18639 0.0135135135135135 0.652534659011343 0.788101766202223 0.909348191771795 GO:0048029 monosaccharide binding 1/386 74/18639 0.0135135135135135 0.652534659011343 0.788101766202223 0.909348191771795 GO:0019003 GDP binding 1/386 75/18639 0.0133333333333333 0.643834196891192 0.792507514559128 0.912598931859256 GO:0051536 iron-sulfur cluster binding 1/386 76/18639 0.0131578947368421 0.635362694300518 0.796821891815117 0.912598931859256 GO:0140034 methylation-dependent protein binding 1/386 76/18639 0.0131578947368421 0.635362694300518 0.796821891815117 0.912598931859256 GO:0008168 methyltransferase activity 3/386 204/18639 0.0147058823529412 0.710111246571167 0.797624712419307 0.912598931859256 GO:0044389 ubiquitin-like protein ligase binding 5/386 322/18639 0.015527950310559 0.749806906317382 0.799888803947673 0.912598931859256 GO:0003724 RNA helicase activity 1/386 77/18639 0.012987012987013 0.627111230738174 0.801046788101243 0.912598931859256 GO:0051540 metal cluster binding 1/386 77/18639 0.012987012987013 0.627111230738174 0.801046788101243 0.912598931859256 GO:0015293 symporter activity 2/386 146/18639 0.0136986301369863 0.661473489956704 0.808603979077867 0.912598931859256 GO:0008186 ATP-dependent activity, acting on RNA 1/386 79/18639 0.0126582278481013 0.6112349970486 0.809235504090186 0.912598931859256 GO:0015370 solute:sodium symporter activity 1/386 79/18639 0.0126582278481013 0.6112349970486 0.809235504090186 0.912598931859256 GO:0033293 monocarboxylic acid binding 1/386 79/18639 0.0126582278481013 0.6112349970486 0.809235504090186 0.912598931859256 GO:0015101 organic cation transmembrane transporter activity 1/386 81/18639 0.0123456790123457 0.596142774899251 0.81708801790478 0.912598931859256 GO:0008509 monoatomic anion transmembrane transporter activity 2/386 149/18639 0.0134228187919463 0.648155231769656 0.81752418024983 0.912598931859256 GO:0019842 vitamin binding 2/386 150/18639 0.0133333333333333 0.643834196891192 0.820414006853802 0.912598931859256 GO:0000510 H3-H4 histone complex chaperone activity 2/386 151/18639 0.0132450331125828 0.639570394262773 0.823262806339416 0.912598931859256 GO:0140584 chromatin extrusion motor activity 2/386 151/18639 0.0132450331125828 0.639570394262773 0.823262806339416 0.912598931859256 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 2/386 151/18639 0.0132450331125828 0.639570394262773 0.823262806339416 0.912598931859256 GO:0140849 ATP-dependent H2AZ histone chaperone activity 2/386 151/18639 0.0132450331125828 0.639570394262773 0.823262806339416 0.912598931859256 GO:0001540 amyloid-beta binding 1/386 83/18639 0.0120481927710843 0.581777888757101 0.824618098537337 0.912598931859256 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/386 83/18639 0.0120481927710843 0.581777888757101 0.824618098537337 0.912598931859256 GO:0005254 chloride channel activity 1/386 83/18639 0.0120481927710843 0.581777888757101 0.824618098537337 0.912598931859256 GO:0008135 translation factor activity, RNA binding 1/386 83/18639 0.0120481927710843 0.581777888757101 0.824618098537337 0.912598931859256 GO:0030165 PDZ domain binding 1/386 83/18639 0.0120481927710843 0.581777888757101 0.824618098537337 0.912598931859256 GO:0016741 transferase activity, transferring one-carbon groups 3/386 215/18639 0.013953488372093 0.673779973490782 0.825589455047296 0.912598931859256 GO:0015616 DNA translocase activity 2/386 152/18639 0.0131578947368421 0.635362694300518 0.826071033134823 0.912598931859256 GO:0140674 ATP-dependent histone chaperone activity 2/386 152/18639 0.0131578947368421 0.635362694300518 0.826071033134823 0.912598931859256 GO:0180051 translation factor activity 1/386 84/18639 0.0119047619047619 0.574851961509993 0.828266374780309 0.912669526644249 GO:0061775 cohesin loader activity 2/386 153/18639 0.0130718954248366 0.631209996952149 0.828839140493221 0.912669526644249 GO:0004386 helicase activity 2/386 155/18639 0.0129032258064516 0.623065351830186 0.834256803167643 0.916833729883643 GO:0016209 antioxidant activity 1/386 86/18639 0.0116279069767442 0.561483311242318 0.83533739833843 0.916833729883643 GO:0140658 ATP-dependent chromatin remodeler activity 2/386 158/18639 0.0126582278481013 0.6112349970486 0.842093649491534 0.92127982190374 GO:0004197 cysteine-type endopeptidase activity 1/386 88/18639 0.0113636363636364 0.548722326895902 0.842118000169789 0.92127982190374 GO:0003727 single-stranded RNA binding 1/386 89/18639 0.0112359550561798 0.542556907492577 0.845403130455729 0.923377205594849 GO:0003689 DNA clamp loader activity 2/386 160/18639 0.0125 0.603594559585492 0.847130309794043 0.923768916172826 GO:0061134 peptidase regulator activity 3/386 226/18639 0.0132743362831858 0.640985373011142 0.850190085208432 0.925610173412406 GO:0043178 alcohol binding 1/386 92/18639 0.0108695652173913 0.524864834422167 0.854855046461675 0.926792833221368 GO:0052689 carboxylic ester hydrolase activity 1/386 92/18639 0.0108695652173913 0.524864834422167 0.854855046461675 0.926792833221368 GO:0015081 sodium ion transmembrane transporter activity 2/386 164/18639 0.0121951219512195 0.588872741059017 0.85676848582242 0.926792833221368 GO:0140713 histone chaperone activity 2/386 164/18639 0.0121951219512195 0.588872741059017 0.85676848582242 0.926792833221368 GO:0015399 primary active transmembrane transporter activity 2/386 166/18639 0.0120481927710843 0.581777888757101 0.86137693262041 0.929853394077469 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 2/386 167/18639 0.0119760479041916 0.578294188824424 0.863629991921072 0.929853394077469 GO:0004867 serine-type endopeptidase inhibitor activity 1/386 95/18639 0.0105263157894737 0.508290155440414 0.863730486054182 0.929853394077469 GO:0019787 ubiquitin-like protein transferase activity 7/386 479/18639 0.0146137787056367 0.705663785736692 0.870656102329724 0.935816670497713 GO:0042626 ATPase-coupled transmembrane transporter activity 1/386 98/18639 0.0102040816326531 0.492730252722851 0.872064523035107 0.935840306913668 GO:0043130 ubiquitin binding 1/386 100/18639 0.01 0.482875647668394 0.877336121290483 0.939742634079325 GO:0003823 antigen binding 2/386 174/18639 0.0114942528735632 0.555029480078614 0.87848533645045 0.939742634079325 GO:0015171 amino acid transmembrane transporter activity 1/386 102/18639 0.00980392156862745 0.473407497714112 0.882391042190542 0.940577994433806 GO:0043021 ribonucleoprotein complex binding 2/386 177/18639 0.0112994350282486 0.545622200755247 0.8843836048939 0.940577994433806 GO:0004722 protein serine/threonine phosphatase activity 1/386 103/18639 0.00970873786407767 0.468811308415916 0.884840039208099 0.940577994433806 GO:0005253 monoatomic anion channel activity 1/386 103/18639 0.00970873786407767 0.468811308415916 0.884840039208099 0.940577994433806 GO:0033218 amide binding 3/386 247/18639 0.0121457489878543 0.586488640892786 0.88887514594754 0.942133123979936 GO:0016853 isomerase activity 2/386 180/18639 0.0111111111111111 0.536528497409326 0.890016374599949 0.942133123979936 GO:0016755 aminoacyltransferase activity 7/386 496/18639 0.0141129032258065 0.681477728564265 0.891796243969123 0.942133123979936 GO:0004497 monooxygenase activity 1/386 106/18639 0.00943396226415094 0.455543063838107 0.891886024034339 0.942133123979936 GO:0004843 cysteine-type deubiquitinase activity 1/386 108/18639 0.00925925925925926 0.447107081174439 0.896342777524571 0.945361523170446 GO:0008234 cysteine-type peptidase activity 2/386 187/18639 0.0106951871657754 0.516444542960849 0.902184727859341 0.950038519976685 GO:0140597 protein carrier chaperone 2/386 188/18639 0.0106382978723404 0.513697497519568 0.903817067261347 0.950274953896276 GO:0004842 ubiquitin-protein transferase activity 6/386 449/18639 0.0133630289532294 0.645268126060214 0.906368644404997 0.95147563759467 GO:0101005 deubiquitinase activity 1/386 115/18639 0.00869565217391304 0.419891867537734 0.910546793898498 0.954377462548892 GO:0022853 active monoatomic ion transmembrane transporter activity 1/386 118/18639 0.00847457627118644 0.409216650566435 0.916023399542207 0.958629139055798 GO:0051082 unfolded protein binding 1/386 121/18639 0.00826446280991736 0.39907078319702 0.921165525570652 0.962518157523514 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/386 122/18639 0.00819672131147541 0.395799711203601 0.922808797367267 0.962744881333702 GO:0019783 ubiquitin-like protein peptidase activity 1/386 127/18639 0.0078740157480315 0.380217045408184 0.930526613388336 0.96782042759266 GO:0031490 chromatin DNA binding 1/386 128/18639 0.0078125 0.377246599740933 0.93197522657071 0.96782042759266 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 1/386 128/18639 0.0078125 0.377246599740933 0.93197522657071 0.96782042759266 GO:0008094 ATP-dependent activity, acting on DNA 2/386 210/18639 0.00952380952380952 0.459881569207994 0.933883748315346 0.968312642262456 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/386 132/18639 0.00757575757575758 0.365814884597268 0.937474576298507 0.970369840101344 GO:0015291 secondary active transmembrane transporter activity 3/386 287/18639 0.0104529616724739 0.504748063764872 0.938742971238782 0.970369840101344 GO:0015297 antiporter activity 1/386 135/18639 0.00740740740740741 0.357685664939551 0.941306021333314 0.971309952690151 GO:0016779 nucleotidyltransferase activity 1/386 136/18639 0.00735294117647059 0.355055623285584 0.942530398536369 0.971309952690151 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 2/386 229/18639 0.00873362445414847 0.421725456478946 0.952473033717803 0.980059905121215 GO:0005506 iron ion binding 1/386 154/18639 0.00649350649350649 0.313555615369087 0.960685200715444 0.986831781085338 GO:0022804 active transmembrane transporter activity 5/386 457/18639 0.0109409190371991 0.528310336617499 0.961978239932077 0.986831781085338 GO:0042393 histone binding 2/386 247/18639 0.00809716599190283 0.390992427261857 0.965402222626902 0.988578695868878 GO:0140104 molecular carrier activity 2/386 249/18639 0.00803212851405622 0.387851925838067 0.966610280405125 0.988578695868878 GO:0016874 ligase activity 1/386 167/18639 0.00598802395209581 0.289147094412212 0.970120481942561 0.988877329913303 GO:0003730 mRNA 3'-UTR binding 2/386 262/18639 0.00763358778625954 0.368607364632362 0.973529458208113 0.988877329913303 GO:0004252 serine-type endopeptidase activity 1/386 176/18639 0.00568181818181818 0.274361163447951 0.975293400353662 0.988877329913303 GO:0008514 organic anion transmembrane transporter activity 2/386 269/18639 0.00743494423791822 0.359015351426315 0.976659951182221 0.988877329913303 GO:0061630 ubiquitin protein ligase activity 3/386 353/18639 0.0084985835694051 0.410375904534046 0.978425697302565 0.988877329913303 GO:0045182 translation regulator activity 3/386 356/18639 0.00842696629213483 0.406917680619433 0.979456065030853 0.988877329913303 GO:0015078 proton transmembrane transporter activity 1/386 185/18639 0.00540540540540541 0.261013863604537 0.979572666220558 0.988877329913303 GO:0046943 carboxylic acid transmembrane transporter activity 1/386 188/18639 0.00531914893617021 0.256848748759784 0.980827935842438 0.988877329913303 GO:0005342 organic acid transmembrane transporter activity 1/386 189/18639 0.00529100529100529 0.255489760671108 0.98122902070314 0.988877329913303 GO:0008236 serine-type peptidase activity 1/386 194/18639 0.00515463917525773 0.248904973024945 0.983112332469426 0.988877329913303 GO:0061659 ubiquitin-like protein ligase activity 3/386 372/18639 0.00806451612903226 0.389415844893866 0.984205994946601 0.988877329913303 GO:0017171 serine hydrolase activity 1/386 198/18639 0.00505050505050505 0.243876589731512 0.984482319558132 0.988877329913303 GO:0030371 translation repressor activity 2/386 329/18639 0.0060790273556231 0.293541427154039 0.992225159735027 0.994648929881553 GO:0140097 catalytic activity, acting on DNA 2/386 336/18639 0.00595238095238095 0.287425980754996 0.993175375911358 0.994648929881553 GO:0140098 catalytic activity, acting on RNA 1/386 387/18639 0.00258397932816537 0.12477406916496 0.99972107885011 0.99972107885011