category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	22/61	233/9376	14.5129107155421	COL1A2/BGN/COL4A1/COL1A1/MYH11/ITGA1/ACTG2/TPM1/PDLIM3/COL4A2/LDB3/TPM2/SDC2/THBS1/ACTB/COL6A3/CSRP1/DAAM2/MYL9/ATP1A2/LMOD1/COL5A2	16.9021376386106
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	14/61	203/9376	10.600339174675	COL1A2/COL4A1/COL1A1/ITGA1/ACTN1/MYLK/COL4A2/CAV1/THBS1/ACTB/COL6A3/MYL9/PTK2/CAV2	11.1902045436034
NA	NA	hsa04518	Integrin signaling	11/61	154/9376	10.9789227166276	COL1A2/COL4A1/COL1A1/ITGA1/ACTN1/COL4A2/FRAS1/THBS1/ACTB/COL6A3/PTK2	10.1039360018173
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	9/61	103/9376	13.4305268183989	COL1A2/COL4A1/COL1A1/COL4A2/COL6A3/ATP1A2/COL18A1/SLC8A1/COL5A2	10.2649572122032
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	8/61	89/9376	13.8161724074415	COL1A2/COL4A1/COL1A1/ITGA1/COL4A2/FRAS1/THBS1/COL6A3	9.83048053712367
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	9/61	134/9376	10.3234646439931	CALD1/PPP1R14A/ACTA2/MYH11/ACTG2/MYLK/CACNA1C/MYL9/GUCY1A2	8.79641826055237
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	8/61	99/9376	12.4205994369929	TGFB3/ITGA1/TPM1/TPM2/CACNA1C/ACTB/CACNA2D1/SLC8A1	9.24404060686805
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	8/61	105/9376	11.7108508977361	TGFB3/ITGA1/TPM1/TPM2/CACNA1C/ACTB/CACNA2D1/SLC8A1	8.93129550280466
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	7/61	87/9376	12.3670623704541	TPM1/TPM2/CACNA1C/COX7A1/CACNA2D1/ATP1A2/SLC8A1	8.61950873098981
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	7/61	103/9376	10.4459653031991	COL1A2/COL4A1/COL1A1/TGFB3/ACTN1/COL4A2/PTK2	7.80034757028782
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	9/61	204/9376	6.78109932497589	COL1A2/COL1A1/CAV1/SDC2/THBS1/ACTB/PTK2/CAV2/TIMP3	6.75542408370874
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	10/61	333/9376	4.61576330428789	COL1A2/COL4A1/COL1A1/ITGA1/HEYL/COL4A2/THBS1/COL6A3/CREB3L2/PTK2	5.43656982497835
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	7/61	154/9376	6.98658718330849	TPM1/TPM2/CACNA1C/CREB3L2/CACNA2D1/ATP1A2/SLC8A1	6.06158555258265
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	7/61	166/9376	6.48153268812957	MYLK/CACNA1C/CREB3L2/MYL9/ATP1A2/GUCY1A2/SLC8A1	5.7661423977124
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	8/61	232/9376	5.30016958733748	MYH11/ITGA1/ACTN1/MYLK/ACTB/MYL9/PTK2/GSN	5.36686403804478
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	5/61	78/9376	9.85287936107608	CAV1/SEPTIN2/ACTB/PTK2/CAV2	6.35325376651611
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	6/61	130/9376	7.09407313997478	COL1A2/COL4A1/ACTA2/COL1A1/COL4A2/CREB3L2	5.66189120406549
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	5/61	86/9376	8.93633244376668	ITGA1/CACNA1C/ACTB/CACNA2D1/SLC8A1	5.98301850846198
Cellular Processes	Cell motility	hsa04814	Motor proteins	7/61	194/9376	5.54605374345107	ACTA2/MYH11/ACTG2/TPM1/TPM2/ACTB/MYL9	5.17756920462906
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	6/61	154/9376	5.98850329997871	MYLK/CACNA1C/ACTB/MYL9/CACNA2D1/GUCY1A2	5.05099794027398
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	5/61	101/9376	7.60915435805876	COL1A2/COL4A1/COL1A1/TGFB3/COL4A2	5.40391798154471
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	9/61	362/9376	3.82139298976542	COL1A2/COL4A1/COL1A1/ITGA1/COL4A2/THBS1/COL6A3/CREB3L2/PTK2	4.43014781920013
NA	NA	hsa04517	IgSF CAM signaling	8/61	299/9376	4.11250616810132	MYH11/ACTN1/MYLK/NECTIN2/ACTB/MYL9/PTK2/NTRK3	4.4262279196376
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	5/61	116/9376	6.62521198417185	THY1/ACTN1/ACTB/MYL9/PTK2	4.9331181907927
Organismal Systems	Immune system	hsa04611	Platelet activation	5/61	126/9376	6.09940150923757	COL1A2/COL1A1/MYLK/ACTB/GUCY1A2	4.66329339632386
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	7/61	275/9376	3.91248882265276	MT-ND3/NDUFA4L2/CAV1/CACNA1C/COX7A1/CREB3L2/CAV2	3.96684456078857
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	6/61	205/9376	4.49868052778888	MT-ND3/COL1A2/COL1A1/TGFB3/NDUFA4L2/COX7A1	4.09856661150509
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	5/61	142/9376	5.41214500115447	CAV1/SDC2/ACTB/PTK2/CAV2	4.28704596402934
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	4/61	93/9376	6.61096421646395	ACTN1/NECTIN2/ACTB/MYL9	4.400417915561
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	3/61	50/9376	9.22229508196721	TGFB3/SDC2/THBS1	4.71725638943169
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	3/61	76/9376	6.06729939603106	MYLK/ACTB/ATP1A2	3.58922771699196
NA	NA	hsa04519	Cadherin signaling	7/61	404/9376	2.66320402532057	CDH6/FAT1/CDH13/ACTN1/ACTB/DAAM2/PTK2	2.76535380427213
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	5/61	235/9376	3.27031740495291	MT-ND3/NDUFA4L2/ACTB/COX7A1/CREB3L2	2.85221842698791
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	3/61	86/9376	5.36179946626001	CACNA1C/CREB3L2/ATP1A2	3.28826030433364
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	3/61	93/9376	4.95822316234796	COL4A1/COL4A2/PTK2	3.10425007991965
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	5/61	253/9376	3.03764660143848	ACTN1/SEPTIN2/ACTB/MYL9/PTK2	2.65876169804068
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	4/61	170/9376	3.61658630665381	MYH11/ACTN1/ACTB/MYL9	2.78601317443653
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	3/61	98/9376	4.70525259284041	CACNA1C/CREB3L2/ATP1A2	2.98375252612156
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	3/61	122/9376	3.77962913195378	CACNA1C/CREB3L2/PTK2	2.50069743421055
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	2/61	53/9376	5.8001855861429	ATP1A2/SLC8A1	2.83581076823563
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	4/61	226/9376	2.72044102712897	CACNA1C/CREB3L2/MYL9/ATP1A2	2.1185688830545
Organismal Systems	Digestive system	hsa04978	Mineral absorption	2/61	61/9376	5.0395055092717	ATP1A2/SLC8A1	2.56130217773394
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	4/61	227/9376	2.70845670542356	MT-ND3/NDUFA4L2/COX7A1/PTK2	2.10857580350266
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	3/61	138/9376	3.34141126158232	MT-ND3/NDUFA4L2/COX7A1	2.24226735030999
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	3/61	140/9376	3.29367681498829	ACTA2/MYLK/SLC8A1	2.21265348688057
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	2/61	65/9376	4.72938209331652	CACNA1C/CREB3L2	2.44148759666615
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	3/61	149/9376	3.09472989327759	MT-ND3/NDUFA4L2/CACNA1C	2.08569130408831
Organismal Systems	Endocrine system	hsa04924	Renin secretion	2/61	69/9376	4.4552150154431	CACNA1C/GUCY1A2	2.33106236568429
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	2/61	69/9376	4.4552150154431	CACNA1C/CREB3L2	2.33106236568429
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	2/61	70/9376	4.39156908665105	CAV1/ACTB	2.30476839621922
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	4/61	254/9376	2.42054989028011	MYLK/CACNA1C/NTRK3/SLC8A1	1.85732301947996
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	2/61	75/9376	4.09879781420765	CREB3L2/ATP1A2	2.18030964791683
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	4/61	268/9376	2.2941032542207	MT-ND3/MAPT/NDUFA4L2/COX7A1	1.73933782448392
NA	NA	hsa03273	Virion - Lassa virus and SFTS virus	1/61	17/9376	9.04146576663452	MYH11	2.68536967700656
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	5/61	388/9376	1.98073347980395	MT-ND3/MAPT/NDUFA4L2/CACNA1C/COX7A1	1.59659387294988
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	3/61	184/9376	2.50605844618674	SEMA5B/MYL9/PTK2	1.66957085865698
Organismal Systems	Digestive system	hsa04970	Salivary secretion	2/61	93/9376	3.30548210823198	ATP1A2/GUCY1A2	1.80808224427829
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	4/61	300/9376	2.04939890710382	TGFB3/MAPT/CACNA1C/CACNA2D1	1.49490335786959
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	2/61	97/9376	3.16917356768633	CACNA1C/GUCY1A2	1.73775565150811
Organismal Systems	Excretory system	hsa04964	Proximal tubule bicarbonate reclamation	1/61	23/9376	6.68282252316465	ATP1A2	2.2080640654325
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	4/61	308/9376	1.99616776665957	MT-ND3/NDUFA4L2/COX7A1/CREB3L2	1.43850446294015
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	3/61	205/9376	2.24934026389444	ACTN1/CREB3L2/GSN	1.46355297413874
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	2/61	106/9376	2.90009279307145	ERG/CREB3L2	1.59201443915604
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	3/61	212/9376	2.17506959480359	THBS1/ACTB/RAPGEF5	1.40038711203981
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	2/61	110/9376	2.7946348733234	TGFB3/THBS1	1.53209404108502
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	2/61	115/9376	2.67312900926586	CACNA1C/CREB3L2	1.46085978342554
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	2/61	122/9376	2.51975275463585	ACTB/ATP1A2	1.36724779952245
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	5/61	480/9376	1.60109289617486	MT-ND3/MAPT/NDUFA4L2/CACNA1C/COX7A1	1.09401670402527
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	2/61	133/9376	2.31135215086898	CACNA1C/CREB3L2	1.23253086299148
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	4/61	368/9376	1.67070563079116	MT-ND3/NDUFA4L2/ACTB/COX7A1	1.06218655301509
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	1/61	38/9376	4.04486626402071	ATP1A2	1.5219213587422
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	3/61	250/9376	1.84445901639344	RAB31/CAV1/CAV2	1.09513453664601
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	2/61	138/9376	2.22760750772155	ACTB/PTK2	1.17562611862524
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	1/61	41/9376	3.74890043982407	THBS1	1.42742370282281
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	1/61	44/9376	3.49329359165425	CREB3L2	1.34144082708032
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	1/61	47/9376	3.27031740495291	CACNA1C	1.26263285845659
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	2/61	155/9376	1.98328926493919	THBS1/ACTB	0.998889072079295
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	2/61	155/9376	1.98328926493919	CACNA1C/CREB3L2	0.998889072079295
Organismal Systems	Digestive system	hsa04973	Carbohydrate digestion and absorption	1/61	48/9376	3.20218579234973	ATP1A2	1.23776851810735
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	2/61	157/9376	1.95802443353869	THBS1/PTK2	0.97958839236543
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	2/61	157/9376	1.95802443353869	TGFB3/ACTB	0.97958839236543
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	2/61	157/9376	1.95802443353869	NDUFA4L2/COX7A1	0.97958839236543
Metabolism	Glycan biosynthesis and metabolism	hsa00514	Other types of O-glycan biosynthesis	1/61	49/9376	3.13683506189361	ST6GAL2	1.21354861472196
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	1/61	49/9376	3.13683506189361	CREB3L2	1.21354861472196
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	2/61	160/9376	1.92131147540984	NECTIN2/SDC2	0.951161723025969
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	1/61	51/9376	3.01382192221151	ACTB	1.16691939485237
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	2/61	163/9376	1.88594991451272	TGFB3/CREB3L2	0.923339815558307
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	1/61	52/9376	2.95586380832283	LIPG	1.14445382760361
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	2/61	170/9376	1.8082931533269	TGFB3/ACTB	0.86063103221519
Metabolism	Glycan biosynthesis and metabolism	hsa00510	N-Glycan biosynthesis	1/61	56/9376	2.74473067915691	ST6GAL2	1.05967717798296
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/61	60/9376	2.56174863387978	PTK2	0.982044451117275
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/61	60/9376	2.56174863387978	GUCY1A2	0.982044451117275
Environmental Information Processing	Signal transduction	hsa04330	Notch signaling pathway	1/61	62/9376	2.47911158117398	HEYL	0.945557168706802
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	1/61	65/9376	2.36469104665826	LIPG	0.893412415335129
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/61	65/9376	2.36469104665826	CACNA1C	0.893412415335129
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	1/61	66/9376	2.32886239443617	TGFB3	0.87667024175089
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	3/61	323/9376	1.42759985788966	TPM1/THBS1/TIMP3	0.632851303944468
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	1/61	67/9376	2.2941032542207	CACNA1C	0.860228727081944
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	1/61	70/9376	2.19578454332553	TGFB3	0.812605125748885
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	1/61	71/9376	2.16485800046179	NTRK3	0.797265733593521
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	2/61	200/9376	1.53704918032787	MYH11/ACTB	0.621242958941742
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	2/61	201/9376	1.52940216948047	ERG/PTK2	0.613959657345508
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	1/61	73/9376	2.10554682236694	MAP1B	0.767337082136408
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	1/61	75/9376	2.04939890710382	THBS1	0.738355549104093
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	1/61	77/9376	1.99616776665957	TGFB3	0.710262441389831
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/61	77/9376	1.99616776665957	TGFB3	0.710262441389831
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/61	78/9376	1.97057587221522	TGFB3	0.696532118459982
NA	NA	hsa04382	Cornified envelope formation	2/61	217/9376	1.41663518924228	COL4A1/COL4A2	0.502482465608427
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	2/61	217/9376	1.41663518924228	CACNA1C/CREB3L2	0.502482465608427
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	2/61	224/9376	1.37236533957845	TGFB3/CREB3L2	0.456451226970517
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/61	86/9376	1.78726648875334	PTK2	0.593502100205312
Organismal Systems	Sensory system	hsa04742	Taste transduction	1/61	86/9376	1.78726648875334	CACNA1C	0.593502100205312
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	1/61	87/9376	1.76672319577916	TGFB3	0.581397116061293
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	2/61	227/9376	1.35422835271178	CREB3L2/PTK2	0.437188329719767
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	1/61	88/9376	1.74664679582712	CFH	0.569448645800148
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/61	89/9376	1.72702155093019	GUCY1A2	0.557652548614196
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	1/61	89/9376	1.72702155093019	CACNA1C	0.557652548614196
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/61	90/9376	1.70783242258652	CREB3L2	0.546004840603216
Organismal Systems	Digestive system	hsa04976	Bile secretion	1/61	90/9376	1.70783242258652	ATP1A2	0.546004840603216
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	1/61	93/9376	1.65274105411599	CACNA1C	0.511914408636939
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	1/61	95/9376	1.61794650560828	TGFB3	0.489862757773856
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	1/61	98/9376	1.5684175309468	GSN	0.457733231772508
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	1/61	99/9376	1.55257492962411	PTK2	0.44726418398293
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	1/61	99/9376	1.55257492962411	CFH	0.44726418398293
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	1/61	100/9376	1.53704918032787	ITGA1	0.436910834219208
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	2/61	248/9376	1.23955579058699	ACTB/MYL9	0.309388255698216
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/61	101/9376	1.52183087161175	CREB3L2	0.426670505431525
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	1/61	102/9376	1.50691096110575	ATP1A2	0.41654060972804
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	1/61	103/9376	1.49228075759987	TGFB3	0.406518644541614
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/61	107/9376	1.43649456105408	CREB3L2	0.367462825754157
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	1/61	109/9376	1.41013686268612	CREB3L2	0.348523124276768
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	1/61	112/9376	1.37236533957845	TGFB3	0.320802772914364
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/61	115/9376	1.33656450463293	CACNA1C	0.293864696998185
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	1/61	115/9376	1.33656450463293	CREB3L2	0.293864696998185
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	1/61	116/9376	1.32504239683437	CACNA1C	0.285051046096453
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/61	117/9376	1.31371724814348	ACTB	0.276317513234652
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	1/61	119/9376	1.29163796666207	CREB3L2	0.259084562575697
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	1/61	120/9376	1.28087431693989	NTRK3	0.250582135132821
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/61	122/9376	1.25987637731793	CREB3L2	0.233798164834343
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	1/61	128/9376	1.20081967213115	GUCY1A2	0.185117064176699
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	1/61	133/9376	1.15567607543449	TGFB3	0.146318872070518
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	1/61	137/9376	1.12193370826852	ACTB	0.116340441602769
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	1/61	139/9376	1.10579077721429	CREB3L2	0.101683119703416
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	1/61	143/9376	1.07485956666285	ACTN1	0.0729966678383885
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	1/61	148/9376	1.03854674346478	HEYL	0.0382493345999899
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	1/61	150/9376	1.02469945355191	TGFB3	0.024676603079305
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	1/61	157/9376	0.979012216769343	TGFB3	-0.0214601925738913
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	1/61	158/9376	0.972815936916373	TGFB3	-0.0278858371638453
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	1/61	173/9376	0.888467734293566	ACTB	-0.119816875822073
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	1/61	178/9376	0.863510775465095	DAAM2	-0.148771859381902
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	1/61	180/9376	0.85391621129326	NECTIN2	-0.160139298298848
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	1/61	181/9376	0.849198442170093	TGFB3	-0.165778564499951
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/61	191/9376	0.804737790747575	CREB3L2	-0.220624850338311
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	1/61	193/9376	0.796398539029984	PTK2	-0.231273769230517
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	1/61	195/9376	0.788230348886087	ACTB	-0.241821638348075
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	1/61	214/9376	0.718247280527042	PTK2	-0.337395266687427
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	1/61	216/9376	0.711596842744384	PTK2	-0.347007031640515
Genetic Information Processing	Translation	hsa03010	Ribosome	1/61	222/9376	0.692364495643184	RPS26	-0.375376097887682
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	1/61	238/9376	0.645818983331037	RAPGEF5	-0.447865189450503
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	1/61	238/9376	0.645818983331037	RPS26	-0.447865189450503
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	1/61	298/9376	0.515788315546265	TGFB3	-0.687396686046634
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	1/61	449/9376	0.342327211654314	SLC8A1	-1.1556848023887