ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003779 actin binding 19/94 443/18639 0.0428893905191874 8.50441861582057 6.63917908660965e-13 2.07142387502221e-10 GO:0005201 extracellular matrix structural constituent 13/94 168/18639 0.0773809523809524 15.3436550151976 2.59663730748941e-12 4.05075419968348e-10 GO:0030020 extracellular matrix structural constituent conferring tensile strength 7/94 44/18639 0.159090909090909 31.5456963249516 2.17646843985766e-09 2.26352717745197e-07 GO:0019838 growth factor binding 9/94 136/18639 0.0661764705882353 13.1219493116395 2.826379091448e-08 2.20457569132944e-06 GO:0008307 structural constituent of muscle 6/94 42/18639 0.142857142857143 28.3267477203647 6.34338171330088e-08 3.95827018909975e-06 GO:0050840 extracellular matrix binding 6/94 67/18639 0.0895522388059701 17.757065735154 1.09059909598569e-06 5.6711152991256e-05 GO:0048407 platelet-derived growth factor binding 3/94 11/18639 0.272727272727273 54.07833655706 1.99042738318502e-05 0.000887161919362464 GO:0042805 actinin binding 4/94 37/18639 0.108108108108108 21.4364577343301 3.52658391110952e-05 0.00137536772533271 GO:0051015 actin filament binding 7/94 209/18639 0.0334928229665072 6.64119922630561 9.04060090727037e-05 0.00313407498118706 GO:0005178 integrin binding 6/94 161/18639 0.0372670807453416 7.38958636183428 0.000164591958821064 0.0051352691152172 GO:0051393 alpha-actinin binding 3/94 28/18639 0.107142857142857 21.2450607902736 0.000371369979234523 0.0105334030473792 GO:0043236 laminin binding 3/94 29/18639 0.103448275862069 20.5124724871607 0.000412711156792502 0.010730490076605 GO:0071813 lipoprotein particle binding 3/94 32/18639 0.09375 18.5894281914894 0.000554122313156055 0.0123490115503349 GO:0071814 protein-lipid complex binding 3/94 32/18639 0.09375 18.5894281914894 0.000554122313156055 0.0123490115503349 GO:0050998 nitric-oxide synthase binding 2/94 11/18639 0.181818181818182 36.0522243713733 0.00134365101820684 0.0279479411787023 GO:0005080 protein kinase C binding 3/94 52/18639 0.0576923076923077 11.4396481178396 0.00229563159105429 0.0415728924501579 GO:0005200 structural constituent of cytoskeleton 4/94 112/18639 0.0357142857142857 7.08168693009119 0.00248692108696141 0.0415728924501579 GO:0005523 tropomyosin binding 2/94 15/18639 0.133333333333333 26.4382978723404 0.00253168255305449 0.0415728924501579 GO:0051371 muscle alpha-actinin binding 2/94 15/18639 0.133333333333333 26.4382978723404 0.00253168255305449 0.0415728924501579 GO:0030169 low-density lipoprotein particle binding 2/94 17/18639 0.117647058823529 23.3279098873592 0.00325769314374003 0.0489120720667941 GO:0001786 phosphatidylserine binding 3/94 59/18639 0.0508474576271186 10.0824017309773 0.00329215869680345 0.0489120720667941 GO:0005516 calmodulin binding 5/94 207/18639 0.0241545893719807 4.7895467160037 0.0039733374592211 0.0552010850292648 GO:0030506 ankyrin binding 2/94 19/18639 0.105263157894737 20.8723404255319 0.00406931075536247 0.0552010850292648 GO:0044325 transmembrane transporter binding 4/94 136/18639 0.0294117647058824 5.8319774718398 0.00498190827210767 0.0647648075373997 GO:0061134 peptidase regulator activity 5/94 226/18639 0.0221238938053097 4.38688570890604 0.00574499883581581 0.0652700330795274 GO:0005518 collagen binding 3/94 72/18639 0.0416666666666667 8.26196808510638 0.00576196059578709 0.0652700330795274 GO:0099186 structural constituent of postsynapse 2/94 23/18639 0.0869565217391304 17.2423681776133 0.00594235697440722 0.0652700330795274 GO:0022843 voltage-gated monoatomic cation channel activity 4/94 143/18639 0.027972027972028 5.54649605713435 0.00594256695532708 0.0652700330795274 GO:0019955 cytokine binding 4/94 144/18639 0.0277777777777778 5.50797872340426 0.00608916132953575 0.0652700330795274 GO:0050431 transforming growth factor beta binding 2/94 24/18639 0.0833333333333333 16.5239361702128 0.00646140591801917 0.0652700330795274 GO:0017022 myosin binding 3/94 76/18639 0.0394736842105263 7.82712765957447 0.00669436236713101 0.0652700330795274 GO:0098631 cell adhesion mediator activity 3/94 76/18639 0.0394736842105263 7.82712765957447 0.00669436236713101 0.0652700330795274 GO:0005539 glycosaminoglycan binding 5/94 242/18639 0.0206611570247934 4.09684367856515 0.00761939645408914 0.0720379301113882 GO:0004866 endopeptidase inhibitor activity 4/94 161/18639 0.0248447204968944 4.92639090788952 0.00896025230013648 0.08222349169537 GO:0098918 structural constituent of synapse 2/94 30/18639 0.0666666666666667 13.2191489361702 0.00998612535940172 0.0890191746323811 GO:0030414 peptidase inhibitor activity 4/94 169/18639 0.0236686390532544 4.69318897142138 0.0105724039697371 0.091555656619277 GO:0072341 modified amino acid binding 3/94 91/18639 0.032967032967033 6.53694178162263 0.0109592675599287 0.091555656619277 GO:0008201 heparin binding 4/94 172/18639 0.0232558139534884 4.61133102424542 0.0112222470162874 0.091555656619277 GO:0005244 voltage-gated monoatomic ion channel activity 4/94 173/18639 0.023121387283237 4.58467593161973 0.0114444570774096 0.091555656619277 GO:0022832 voltage-gated channel activity 4/94 175/18639 0.0228571428571429 4.53227963525836 0.011897347486926 0.0927993103980229 GO:0005543 phospholipid binding 7/94 497/18639 0.0140845070422535 2.79277794426131 0.0128376279568752 0.09769121762305 GO:0061135 endopeptidase regulator activity 4/94 184/18639 0.0217391304347826 4.31059204440333 0.0140775333851423 0.104575962289629 GO:0043394 proteoglycan binding 2/94 37/18639 0.0540540540540541 10.718228867165 0.0149443955782255 0.108433753962938 GO:0019902 phosphatase binding 4/94 190/18639 0.0210526315789474 4.17446808510638 0.0156631849664444 0.111066220671152 GO:0008013 beta-catenin binding 3/94 106/18639 0.0283018867924528 5.61190285026094 0.0164900355254143 0.114330912976205 GO:1902936 phosphatidylinositol bisphosphate binding 3/94 111/18639 0.027027027027027 5.35911443358252 0.0186229521742393 0.124321123932298 GO:0004857 enzyme inhibitor activity 6/94 416/18639 0.0144230769230769 2.8599120294599 0.0187278616180064 0.124321123932298 GO:0005245 voltage-gated calcium channel activity 2/94 43/18639 0.0465116279069767 9.22266204849085 0.0198712198892989 0.129162929280443 GO:0022853 active monoatomic ion transmembrane transporter activity 3/94 118/18639 0.0254237288135593 5.04120086548864 0.0218547675415986 0.139156887203648 GO:0046873 metal ion transmembrane transporter activity 6/94 450/18639 0.0133333333333333 2.64382978723404 0.0263008806422127 0.164117495207407 GO:0045296 cadherin binding 5/94 334/18639 0.0149700598802395 2.96837176710409 0.0269837024769076 0.165076768094023 GO:0051087 protein-folding chaperone binding 3/94 134/18639 0.0223880597014925 4.4392664337885 0.0303205036087294 0.181923021652376 GO:0002020 protease binding 3/94 136/18639 0.0220588235294118 4.37398310387985 0.0314838945007685 0.185339152532826 GO:0015459 potassium channel regulator activity 2/94 59/18639 0.0338983050847458 6.72160115398485 0.0357523794203108 0.206312033543845 GO:0019903 protein phosphatase binding 3/94 144/18639 0.0208333333333333 4.13098404255319 0.0363691084772804 0.206312033543845 GO:0015085 calcium ion transmembrane transporter activity 3/94 147/18639 0.0204081632653061 4.04667824576639 0.0382959876699007 0.212959569899723 GO:0046982 protein heterodimerization activity 5/94 369/18639 0.013550135501355 2.68681888946549 0.0389060752701418 0.212959569899723 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 2/94 68/18639 0.0294117647058824 5.8319774718398 0.0462408348090843 0.229649315820012 GO:0015079 potassium ion transmembrane transporter activity 3/94 160/18639 0.01875 3.71788563829787 0.0472348597124964 0.229649315820012 GO:0097110 scaffold protein binding 2/94 70/18639 0.0285714285714286 5.66534954407295 0.0487078624469681 0.229649315820012 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/94 10/18639 0.1 19.8287234042553 0.0493142661770236 0.229649315820012 GO:0030957 Tat protein binding 1/94 10/18639 0.1 19.8287234042553 0.0493142661770236 0.229649315820012 GO:0042975 peroxisome proliferator activated receptor binding 1/94 10/18639 0.1 19.8287234042553 0.0493142661770236 0.229649315820012 GO:0043121 neurotrophin binding 1/94 10/18639 0.1 19.8287234042553 0.0493142661770236 0.229649315820012 GO:0070097 delta-catenin binding 1/94 10/18639 0.1 19.8287234042553 0.0493142661770236 0.229649315820012 GO:1901681 sulfur compound binding 4/94 275/18639 0.0145454545454545 2.88417794970986 0.0504724428896715 0.229649315820012 GO:0015399 primary active transmembrane transporter activity 3/94 166/18639 0.0180722891566265 3.5835042296847 0.0516777013917717 0.229649315820012 GO:0001851 complement component C3b binding 1/94 11/18639 0.0909090909090909 18.0261121856867 0.0541113276929049 0.229649315820012 GO:0005114 type II transforming growth factor beta receptor binding 1/94 11/18639 0.0909090909090909 18.0261121856867 0.0541113276929049 0.229649315820012 GO:0008432 JUN kinase binding 1/94 11/18639 0.0909090909090909 18.0261121856867 0.0541113276929049 0.229649315820012 GO:0019215 intermediate filament binding 1/94 11/18639 0.0909090909090909 18.0261121856867 0.0541113276929049 0.229649315820012 GO:0034713 type I transforming growth factor beta receptor binding 1/94 11/18639 0.0909090909090909 18.0261121856867 0.0541113276929049 0.229649315820012 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/94 11/18639 0.0909090909090909 18.0261121856867 0.0541113276929049 0.229649315820012 GO:0031267 small GTPase binding 4/94 283/18639 0.0141342756183746 2.80264641756259 0.0549809416238084 0.229649315820012 GO:0035091 phosphatidylinositol binding 4/94 284/18639 0.0140845070422535 2.79277794426131 0.0555594382359133 0.229649315820012 GO:0015368 calcium:monoatomic cation antiporter activity 1/94 12/18639 0.0833333333333333 16.5239361702128 0.0588844399538492 0.229649315820012 GO:0017166 vinculin binding 1/94 12/18639 0.0833333333333333 16.5239361702128 0.0588844399538492 0.229649315820012 GO:0034452 dynactin binding 1/94 12/18639 0.0833333333333333 16.5239361702128 0.0588844399538492 0.229649315820012 GO:0035259 nuclear glucocorticoid receptor binding 1/94 12/18639 0.0833333333333333 16.5239361702128 0.0588844399538492 0.229649315820012 GO:0035497 cAMP response element binding 1/94 12/18639 0.0833333333333333 16.5239361702128 0.0588844399538492 0.229649315820012 GO:0046332 SMAD binding 2/94 79/18639 0.0253164556962025 5.01992997576084 0.0603735466268404 0.232549957377459 GO:0004465 lipoprotein lipase activity 1/94 13/18639 0.0769230769230769 15.2528641571195 0.0636337212468295 0.233573188576598 GO:0008253 5'-nucleotidase activity 1/94 13/18639 0.0769230769230769 15.2528641571195 0.0636337212468295 0.233573188576598 GO:0030955 potassium ion binding 1/94 13/18639 0.0769230769230769 15.2528641571195 0.0636337212468295 0.233573188576598 GO:0045159 myosin II binding 1/94 13/18639 0.0769230769230769 15.2528641571195 0.0636337212468295 0.233573188576598 GO:1901981 phosphatidylinositol phosphate binding 3/94 185/18639 0.0162162162162162 3.21546866014951 0.0670193716137394 0.236978869507156 GO:0008191 metalloendopeptidase inhibitor activity 1/94 14/18639 0.0714285714285714 14.1633738601824 0.0683592892809103 0.236978869507156 GO:0008331 high voltage-gated calcium channel activity 1/94 14/18639 0.0714285714285714 14.1633738601824 0.0683592892809103 0.236978869507156 GO:0032036 myosin heavy chain binding 1/94 14/18639 0.0714285714285714 14.1633738601824 0.0683592892809103 0.236978869507156 GO:0042043 neurexin family protein binding 1/94 14/18639 0.0714285714285714 14.1633738601824 0.0683592892809103 0.236978869507156 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 2/94 86/18639 0.0232558139534884 4.61133102424542 0.0700375814853852 0.239948563066246 GO:0004129 cytochrome-c oxidase activity 1/94 15/18639 0.0666666666666667 13.2191489361702 0.073061261190043 0.239948563066246 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/94 15/18639 0.0666666666666667 13.2191489361702 0.073061261190043 0.239948563066246 GO:0008252 nucleotidase activity 1/94 15/18639 0.0666666666666667 13.2191489361702 0.073061261190043 0.239948563066246 GO:0050780 dopamine receptor binding 1/94 15/18639 0.0666666666666667 13.2191489361702 0.073061261190043 0.239948563066246 GO:0051020 GTPase binding 4/94 315/18639 0.0126984126984127 2.51793313069909 0.0751147236908271 0.244122851995188 GO:0022836 gated channel activity 4/94 318/18639 0.0125786163522013 2.49417904456042 0.077171083018473 0.244998011143256 GO:0008142 oxysterol binding 1/94 16/18639 0.0625 12.3929521276596 0.0777397535358408 0.244998011143256 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/94 16/18639 0.0625 12.3929521276596 0.0777397535358408 0.244998011143256 GO:0042562 hormone binding 2/94 94/18639 0.0212765957446809 4.21887732005432 0.0816508042608261 0.251847750062443 GO:0046965 nuclear retinoid X receptor binding 1/94 17/18639 0.0588235294117647 11.6639549436796 0.0823948823103473 0.251847750062443 GO:0070492 oligosaccharide binding 1/94 17/18639 0.0588235294117647 11.6639549436796 0.0823948823103473 0.251847750062443 GO:0004867 serine-type endopeptidase inhibitor activity 2/94 95/18639 0.0210526315789474 4.17446808510638 0.0831420456936911 0.251847750062443 GO:0034185 apolipoprotein binding 1/94 18/18639 0.0555555555555556 11.0159574468085 0.0870267629387879 0.257570082955687 GO:0070628 proteasome binding 1/94 18/18639 0.0555555555555556 11.0159574468085 0.0870267629387879 0.257570082955687 GO:0005249 voltage-gated potassium channel activity 2/94 98/18639 0.0204081632653061 4.04667824576639 0.0876656131918971 0.257570082955687 GO:0005520 insulin-like growth factor binding 1/94 19/18639 0.0526315789473684 10.436170212766 0.0916355102823116 0.257570082955687 GO:0008301 DNA binding, bending 1/94 19/18639 0.0526315789473684 10.436170212766 0.0916355102823116 0.257570082955687 GO:0031420 alkali metal ion binding 1/94 19/18639 0.0526315789473684 10.436170212766 0.0916355102823116 0.257570082955687 GO:0043395 heparan sulfate proteoglycan binding 1/94 19/18639 0.0526315789473684 10.436170212766 0.0916355102823116 0.257570082955687 GO:1990380 K48-linked deubiquitinase activity 1/94 19/18639 0.0526315789473684 10.436170212766 0.0916355102823116 0.257570082955687 GO:0005261 monoatomic cation channel activity 4/94 341/18639 0.0117302052785924 2.32594995944344 0.093862290129864 0.261473522504621 GO:0030742 GTP-dependent protein binding 1/94 20/18639 0.05 9.91436170212766 0.0962212386407146 0.265672800494716 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 5/94 484/18639 0.0103305785123967 2.04842183928257 0.0978982397765893 0.267932024651718 GO:0001846 opsonin binding 1/94 21/18639 0.0476190476190476 9.44224924012158 0.100784061755156 0.268757498013748 GO:0008373 sialyltransferase activity 1/94 21/18639 0.0476190476190476 9.44224924012158 0.100784061755156 0.268757498013748 GO:0009975 cyclase activity 1/94 21/18639 0.0476190476190476 9.44224924012158 0.100784061755156 0.268757498013748 GO:0001216 DNA-binding transcription activator activity 5/94 491/18639 0.010183299389002 2.01921826927244 0.102457634756797 0.270702183004375 GO:0005496 steroid binding 2/94 108/18639 0.0185185185185185 3.67198581560284 0.103248589030515 0.270702183004375 GO:0008970 phospholipase A1 activity 1/94 22/18639 0.0454545454545455 9.01305609284333 0.105324092810855 0.271579478983362 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/94 22/18639 0.0454545454545455 9.01305609284333 0.105324092810855 0.271579478983362 GO:0016849 phosphorus-oxygen lyase activity 1/94 23/18639 0.0434782608695652 8.62118408880666 0.109841444439784 0.272560807682653 GO:0017134 fibroblast growth factor binding 1/94 23/18639 0.0434782608695652 8.62118408880666 0.109841444439784 0.272560807682653 GO:0004806 triacylglycerol lipase activity 1/94 24/18639 0.0416666666666667 8.26196808510638 0.11433622872334 0.272560807682653 GO:0030215 semaphorin receptor binding 1/94 24/18639 0.0416666666666667 8.26196808510638 0.11433622872334 0.272560807682653 GO:0035401 histone H3Y41 kinase activity 2/94 115/18639 0.0173913043478261 3.44847363552266 0.114573872448687 0.272560807682653 GO:0140801 histone H2AXY142 kinase activity 2/94 115/18639 0.0173913043478261 3.44847363552266 0.114573872448687 0.272560807682653 GO:0009055 electron transfer activity 2/94 116/18639 0.0172413793103448 3.41874541452678 0.116217237257045 0.272560807682653 GO:0019208 phosphatase regulator activity 2/94 117/18639 0.0170940170940171 3.38952536824877 0.117866658956888 0.272560807682653 GO:0001848 complement binding 1/94 25/18639 0.04 7.93148936170213 0.118808557195003 0.272560807682653 GO:0005251 delayed rectifier potassium channel activity 1/94 25/18639 0.04 7.93148936170213 0.118808557195003 0.272560807682653 GO:0015271 outward rectifier potassium channel activity 1/94 25/18639 0.04 7.93148936170213 0.118808557195003 0.272560807682653 GO:0015662 P-type ion transporter activity 1/94 25/18639 0.04 7.93148936170213 0.118808557195003 0.272560807682653 GO:0019211 phosphatase activator activity 1/94 25/18639 0.04 7.93148936170213 0.118808557195003 0.272560807682653 GO:0042974 nuclear retinoic acid receptor binding 1/94 25/18639 0.04 7.93148936170213 0.118808557195003 0.272560807682653 GO:0140358 P-type transmembrane transporter activity 1/94 25/18639 0.04 7.93148936170213 0.118808557195003 0.272560807682653 GO:0005112 Notch binding 1/94 26/18639 0.0384615384615385 7.62643207855974 0.123258540842992 0.276666652827434 GO:0005160 transforming growth factor beta receptor binding 1/94 26/18639 0.0384615384615385 7.62643207855974 0.123258540842992 0.276666652827434 GO:0043548 phosphatidylinositol 3-kinase binding 1/94 26/18639 0.0384615384615385 7.62643207855974 0.123258540842992 0.276666652827434 GO:0005267 potassium channel activity 2/94 124/18639 0.0161290322580645 3.19818119423473 0.129573812844254 0.288764497195766 GO:0045499 chemorepellent activity 1/94 28/18639 0.0357142857142857 7.08168693009119 0.132091914910307 0.29023012290152 GO:0046966 nuclear thyroid hormone receptor binding 1/94 28/18639 0.0357142857142857 7.08168693009119 0.132091914910307 0.29023012290152 GO:0051861 glycolipid binding 1/94 29/18639 0.0344827586206897 6.83749082905356 0.136475524603415 0.297764780952906 GO:0001968 fibronectin binding 1/94 30/18639 0.0333333333333333 6.60957446808511 0.140837228025623 0.298380368499857 GO:0022839 monoatomic ion-gated channel activity 1/94 30/18639 0.0333333333333333 6.60957446808511 0.140837228025623 0.298380368499857 GO:0048019 receptor antagonist activity 1/94 30/18639 0.0333333333333333 6.60957446808511 0.140837228025623 0.298380368499857 GO:0051721 protein phosphatase 2A binding 1/94 30/18639 0.0333333333333333 6.60957446808511 0.140837228025623 0.298380368499857 GO:0005262 calcium channel activity 2/94 131/18639 0.0152671755725191 3.02728601591684 0.141539405570445 0.298380368499857 GO:0140311 protein sequestering activity 1/94 33/18639 0.0303030303030303 6.00870406189555 0.153791981033181 0.322034215317801 GO:0004713 protein tyrosine kinase activity 2/94 140/18639 0.0142857142857143 2.83267477203647 0.157252809757227 0.327085844295031 GO:0016791 phosphatase activity 3/94 273/18639 0.010989010989011 2.17898059387421 0.159424453858845 0.329406818569268 GO:0020037 heme binding 2/94 142/18639 0.0140845070422535 2.79277794426131 0.160789210300315 0.330041010616437 GO:0005126 cytokine receptor binding 3/94 275/18639 0.0109090909090909 2.1631334622824 0.161851683903905 0.330050492666786 GO:0000146 microfilament motor activity 1/94 38/18639 0.0263157894736842 5.21808510638298 0.174955115214261 0.354454519135387 GO:0046906 tetrapyrrole binding 2/94 152/18639 0.0131578947368421 2.60904255319149 0.178679735952235 0.358248945462109 GO:0000217 DNA secondary structure binding 1/94 39/18639 0.0256410256410256 5.08428805237316 0.179124472731054 0.358248945462109 GO:0030331 nuclear estrogen receptor binding 1/94 40/18639 0.025 4.95718085106383 0.183272983460263 0.362601131511028 GO:0008137 NADH dehydrogenase (ubiquinone) activity 1/94 41/18639 0.024390243902439 4.83627400103788 0.187400750520575 0.362601131511028 GO:0042169 SH2 domain binding 1/94 41/18639 0.024390243902439 4.83627400103788 0.187400750520575 0.362601131511028 GO:0140828 metal cation:monoatomic cation antiporter activity 1/94 41/18639 0.024390243902439 4.83627400103788 0.187400750520575 0.362601131511028 GO:0005216 monoatomic ion channel activity 4/94 448/18639 0.00892857142857143 1.7704217325228 0.190218386037529 0.362601131511028 GO:0019894 kinesin binding 1/94 42/18639 0.0238095238095238 4.72112462006079 0.191507876526116 0.362601131511028 GO:0031492 nucleosomal DNA binding 1/94 42/18639 0.0238095238095238 4.72112462006079 0.191507876526116 0.362601131511028 GO:0051879 Hsp90 protein binding 1/94 42/18639 0.0238095238095238 4.72112462006079 0.191507876526116 0.362601131511028 GO:0099106 ion channel regulator activity 2/94 160/18639 0.0125 2.47859042553192 0.193205512651338 0.362601131511028 GO:0008200 ion channel inhibitor activity 1/94 43/18639 0.0232558139534884 4.61133102424542 0.195594463588898 0.362601131511028 GO:0048156 tau protein binding 1/94 43/18639 0.0232558139534884 4.61133102424542 0.195594463588898 0.362601131511028 GO:0022804 active transmembrane transporter activity 4/94 457/18639 0.0087527352297593 1.73555565901578 0.199462805994754 0.362601131511028 GO:0003954 NADH dehydrogenase activity 1/94 44/18639 0.0227272727272727 4.50652804642166 0.199660613321241 0.362601131511028 GO:0016248 channel inhibitor activity 1/94 44/18639 0.0227272727272727 4.50652804642166 0.199660613321241 0.362601131511028 GO:0030547 signaling receptor inhibitor activity 1/94 44/18639 0.0227272727272727 4.50652804642166 0.199660613321241 0.362601131511028 GO:0015081 sodium ion transmembrane transporter activity 2/94 164/18639 0.0121951219512195 2.41813700051894 0.200526702584316 0.362601131511028 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/94 45/18639 0.0222222222222222 4.4063829787234 0.203706426838197 0.362601131511028 GO:0141110 transporter inhibitor activity 1/94 45/18639 0.0222222222222222 4.4063829787234 0.203706426838197 0.362601131511028 GO:0016247 channel regulator activity 2/94 168/18639 0.0119047619047619 2.36056231003039 0.207880900454299 0.362601131511028 GO:0141108 transporter regulator activity 2/94 170/18639 0.0117647058823529 2.33279098873592 0.211569059261749 0.362601131511028 GO:0005004 GPI-linked ephrin receptor activity 1/94 49/18639 0.0204081632653061 4.04667824576639 0.219688323783251 0.362601131511028 GO:0005008 hepatocyte growth factor receptor activity 1/94 49/18639 0.0204081632653061 4.04667824576639 0.219688323783251 0.362601131511028 GO:0005009 insulin receptor activity 1/94 49/18639 0.0204081632653061 4.04667824576639 0.219688323783251 0.362601131511028 GO:0005011 macrophage colony-stimulating factor receptor activity 1/94 49/18639 0.0204081632653061 4.04667824576639 0.219688323783251 0.362601131511028 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/94 49/18639 0.0204081632653061 4.04667824576639 0.219688323783251 0.362601131511028 GO:0005020 stem cell factor receptor activity 1/94 49/18639 0.0204081632653061 4.04667824576639 0.219688323783251 0.362601131511028 GO:0008288 boss receptor activity 1/94 49/18639 0.0204081632653061 4.04667824576639 0.219688323783251 0.362601131511028 GO:0036332 placental growth factor receptor activity 1/94 49/18639 0.0204081632653061 4.04667824576639 0.219688323783251 0.362601131511028 GO:0038062 protein tyrosine kinase collagen receptor activity 1/94 49/18639 0.0204081632653061 4.04667824576639 0.219688323783251 0.362601131511028 GO:0060175 brain-derived neurotrophic factor receptor activity 1/94 49/18639 0.0204081632653061 4.04667824576639 0.219688323783251 0.362601131511028 GO:0005006 epidermal growth factor receptor activity 1/94 50/18639 0.02 3.96574468085106 0.22363395571248 0.362601131511028 GO:0005007 fibroblast growth factor receptor activity 1/94 50/18639 0.02 3.96574468085106 0.22363395571248 0.362601131511028 GO:0005017 platelet-derived growth factor receptor activity 1/94 50/18639 0.02 3.96574468085106 0.22363395571248 0.362601131511028 GO:0005019 platelet-derived growth factor beta-receptor activity 1/94 50/18639 0.02 3.96574468085106 0.22363395571248 0.362601131511028 GO:0048020 CCR chemokine receptor binding 1/94 50/18639 0.02 3.96574468085106 0.22363395571248 0.362601131511028 GO:0005010 insulin-like growth factor receptor activity 1/94 51/18639 0.0196078431372549 3.88798498122653 0.227559847807968 0.362601131511028 GO:0005021 vascular endothelial growth factor receptor activity 1/94 51/18639 0.0196078431372549 3.88798498122653 0.227559847807968 0.362601131511028 GO:0005030 neurotrophin receptor activity 1/94 51/18639 0.0196078431372549 3.88798498122653 0.227559847807968 0.362601131511028 GO:0030695 GTPase regulator activity 4/94 489/18639 0.0081799591002045 1.62198146456076 0.233371305998905 0.362601131511028 GO:0003924 GTPase activity 3/94 331/18639 0.00906344410876133 1.79716526322556 0.233671099812169 0.362601131511028 GO:0060589 nucleoside-triphosphatase regulator activity 4/94 490/18639 0.00816326530612245 1.61867129830656 0.234454198985356 0.362601131511028 GO:0004864 protein phosphatase inhibitor activity 1/94 53/18639 0.0188679245283019 3.74126856684063 0.235352802823067 0.362601131511028 GO:0005003 ephrin receptor activity 1/94 53/18639 0.0188679245283019 3.74126856684063 0.235352802823067 0.362601131511028 GO:0005005 transmembrane-ephrin receptor activity 1/94 53/18639 0.0188679245283019 3.74126856684063 0.235352802823067 0.362601131511028 GO:0038064 collagen receptor activity 1/94 53/18639 0.0188679245283019 3.74126856684063 0.235352802823067 0.362601131511028 GO:0051018 protein kinase A binding 1/94 53/18639 0.0188679245283019 3.74126856684063 0.235352802823067 0.362601131511028 GO:0015485 cholesterol binding 1/94 54/18639 0.0185185185185185 3.67198581560284 0.239220059711834 0.362601131511028 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 1/94 54/18639 0.0185185185185185 3.67198581560284 0.239220059711834 0.362601131511028 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 1/94 54/18639 0.0185185185185185 3.67198581560284 0.239220059711834 0.362601131511028 GO:0015078 proton transmembrane transporter activity 2/94 185/18639 0.0108108108108108 2.14364577343301 0.239409721446384 0.362601131511028 GO:0098632 cell-cell adhesion mediator activity 1/94 55/18639 0.0181818181818182 3.60522243713733 0.243067964709794 0.364601947064691 GO:0140313 molecular sequestering activity 1/94 55/18639 0.0181818181818182 3.60522243713733 0.243067964709794 0.364601947064691 GO:0019212 phosphatase inhibitor activity 1/94 56/18639 0.0178571428571429 3.54084346504559 0.246896613618387 0.368572935162377 GO:0004601 peroxidase activity 1/94 57/18639 0.0175438596491228 3.47872340425532 0.250706101769916 0.370712340057886 GO:0016504 peptidase activator activity 1/94 57/18639 0.0175438596491228 3.47872340425532 0.250706101769916 0.370712340057886 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 1/94 58/18639 0.0172413793103448 3.41874541452678 0.254496524029825 0.374542054232573 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 3/94 349/18639 0.00859598853868195 1.70447479119673 0.257919947113806 0.376540224940532 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 1/94 59/18639 0.0169491525423729 3.36080057699243 0.258267974798955 0.376540224940532 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/94 60/18639 0.0166666666666667 3.30478723404255 0.262020548015795 0.380234469678736 GO:0141003 histone H2AX kinase activity 3/94 354/18639 0.00847457627118644 1.68040028849621 0.264720592603319 0.382098401813469 GO:0015026 coreceptor activity 1/94 61/18639 0.0163934426229508 3.25061039414022 0.265754337158727 0.382098401813469 GO:0140996 histone H3 kinase activity 3/94 357/18639 0.00840336134453781 1.66627927766851 0.268812216106845 0.38472207075842 GO:0035173 histone kinase activity 3/94 360/18639 0.00833333333333333 1.65239361702128 0.272911556008161 0.388805504449983 GO:0042578 phosphoric ester hydrolase activity 3/94 363/18639 0.00826446280991736 1.63873747142606 0.277018038328182 0.392861945265422 GO:0016500 protein-hormone receptor activity 1/94 67/18639 0.0149253731343284 2.959510955859 0.287767783838935 0.40626040071379 GO:0032934 sterol binding 1/94 68/18639 0.0147058823529412 2.9159887359199 0.291372663675201 0.409496716516499 GO:0002039 p53 binding 1/94 69/18639 0.0144927536231884 2.87372802960222 0.294959490965844 0.412678749692123 GO:0005525 GTP binding 3/94 378/18639 0.00793650793650794 1.57370820668693 0.297637958751976 0.414567156833109 GO:0042379 chemokine receptor binding 1/94 72/18639 0.0138888888888889 2.75398936170213 0.305612549738813 0.42378273563782 GO:0015631 tubulin binding 3/94 385/18639 0.00779220779220779 1.54509533020171 0.307297545505218 0.424233779635522 GO:0031491 nucleosome binding 1/94 74/18639 0.0135135135135135 2.67955721679126 0.312625954213369 0.429688536187538 GO:0003725 double-stranded RNA binding 1/94 75/18639 0.0133333333333333 2.64382978723404 0.316106329128744 0.430677618725626 GO:0019003 GDP binding 1/94 75/18639 0.0133333333333333 2.64382978723404 0.316106329128744 0.430677618725626 GO:0005085 guanyl-nucleotide exchange factor activity 2/94 230/18639 0.00869565217391304 1.72423681776133 0.323339874501197 0.438617568888581 GO:0019199 transmembrane receptor protein kinase activity 1/94 78/18639 0.0128205128205128 2.54214402618658 0.326443185376 0.439259154164554 GO:0019001 guanyl nucleotide binding 3/94 400/18639 0.0075 1.48715425531915 0.328036483719042 0.439259154164554 GO:0032561 guanyl ribonucleotide binding 3/94 400/18639 0.0075 1.48715425531915 0.328036483719042 0.439259154164554 GO:0001618 virus receptor activity 1/94 81/18639 0.0123456790123457 2.44799054373522 0.336625440238098 0.448833920317464 GO:0140272 exogenous protein binding 1/94 82/18639 0.0121951219512195 2.41813700051894 0.339985565715931 0.451385091503704 GO:0030165 PDZ domain binding 1/94 83/18639 0.0120481927710843 2.3890028197898 0.343328851636214 0.453892380129232 GO:0004860 protein kinase inhibitor activity 1/94 84/18639 0.0119047619047619 2.36056231003039 0.346655381488887 0.454438987498036 GO:0051117 ATPase binding 1/94 84/18639 0.0119047619047619 2.36056231003039 0.346655381488887 0.454438987498036 GO:0016209 antioxidant activity 1/94 86/18639 0.0116279069767442 2.30566551212271 0.353258504905825 0.46115754615321 GO:0004197 cysteine-type endopeptidase activity 1/94 88/18639 0.0113636363636364 2.25326402321083 0.359795595732676 0.465793468334419 GO:0016651 oxidoreductase activity, acting on NAD(P)H 1/94 88/18639 0.0113636363636364 2.25326402321083 0.359795595732676 0.465793468334419 GO:0019210 kinase inhibitor activity 1/94 90/18639 0.0111111111111111 2.2031914893617 0.366267307278773 0.472212396161062 GO:0043178 alcohol binding 1/94 92/18639 0.0108695652173913 2.15529602220166 0.37267428645934 0.478495380145325 GO:0004725 protein tyrosine phosphatase activity 1/94 98/18639 0.0102040816326531 2.0233391228832 0.391513204344328 0.497837404325898 GO:0042626 ATPase-coupled transmembrane transporter activity 1/94 98/18639 0.0102040816326531 2.0233391228832 0.391513204344328 0.497837404325898 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 2/94 268/18639 0.00746268656716418 1.4797554779295 0.392525645718497 0.497837404325898 GO:0043130 ubiquitin binding 1/94 100/18639 0.01 1.98287234042553 0.397667597487051 0.500540129982503 GO:0005096 GTPase activator activity 2/94 271/18639 0.00738007380073801 1.46337442097825 0.397865231524554 0.500540129982503 GO:0008017 microtubule binding 2/94 276/18639 0.0072463768115942 1.43686401480111 0.406717207226392 0.509621560861986 GO:0001217 DNA-binding transcription repressor activity 2/94 278/18639 0.00719424460431655 1.42652686361549 0.410240939663329 0.511980692699835 GO:0019888 protein phosphatase regulator activity 1/94 107/18639 0.00934579439252336 1.85315172002386 0.418726927314218 0.520489248294964 GO:0004843 cysteine-type deubiquitinase activity 1/94 108/18639 0.00925925925925926 1.83599290780142 0.421675322999113 0.522074209427473 GO:0004620 phospholipase activity 1/94 109/18639 0.00917431192660551 1.81914893617021 0.424608921813968 0.523628393699439 GO:0004222 metalloendopeptidase activity 1/94 110/18639 0.00909090909090909 1.80261121856867 0.427527797224086 0.525152254857933 GO:0017124 SH3 domain binding 1/94 115/18639 0.00869565217391304 1.72423681776133 0.441903869330794 0.538044749024263 GO:0101005 deubiquitinase activity 1/94 115/18639 0.00869565217391304 1.72423681776133 0.441903869330794 0.538044749024263 GO:0001664 G protein-coupled receptor binding 2/94 297/18639 0.00673400673400673 1.33526756931012 0.443197116984729 0.538044749024263 GO:0140297 DNA-binding transcription factor binding 3/94 488/18639 0.00614754098360656 1.21897889780258 0.448029854374959 0.541803544825532 GO:0032182 ubiquitin-like protein binding 1/94 120/18639 0.00833333333333333 1.65239361702128 0.455922670697301 0.549219587867018 GO:0003697 single-stranded DNA binding 1/94 121/18639 0.00826446280991736 1.63873747142606 0.458684335417558 0.55042120250107 GO:0019783 ubiquitin-like protein peptidase activity 1/94 127/18639 0.0078740157480315 1.56131680348467 0.474965464901309 0.565607729195452 GO:0042826 histone deacetylase binding 1/94 127/18639 0.0078740157480315 1.56131680348467 0.474965464901309 0.565607729195452 GO:0031490 chromatin DNA binding 1/94 128/18639 0.0078125 1.54911901595745 0.477631478638305 0.566619852985366 GO:0016298 lipase activity 1/94 130/18639 0.00769230769230769 1.52528641571195 0.482923390208057 0.570727642973158 GO:0031072 heat shock protein binding 1/94 131/18639 0.00763358778625954 1.51364300795842 0.485549420859115 0.571665733237901 GO:0015297 antiporter activity 1/94 135/18639 0.00740740740740741 1.46879432624113 0.495922243599372 0.581683233094 GO:0099094 ligand-gated monoatomic cation channel activity 1/94 136/18639 0.00735294117647059 1.45799436795995 0.498482949884589 0.582496930202217 GO:0016922 nuclear receptor binding 1/94 137/18639 0.0072992700729927 1.44735207330331 0.501030785517235 0.58328957119917 GO:0003774 cytoskeletal motor activity 1/94 153/18639 0.0065359477124183 1.29599499374218 0.540097019395651 0.62643223067451 GO:0008083 growth factor activity 1/94 162/18639 0.00617283950617284 1.22399527186761 0.560725506805568 0.647949474530878 GO:0003735 structural constituent of ribosome 1/94 175/18639 0.00571428571428571 1.13306990881459 0.588915902774695 0.675521182594503 GO:0004721 phosphoprotein phosphatase activity 1/94 175/18639 0.00571428571428571 1.13306990881459 0.588915902774695 0.675521182594503 GO:0008237 metallopeptidase activity 1/94 184/18639 0.00543478260869565 1.07764801110083 0.607376196729966 0.693062607361495 GO:0004175 endopeptidase activity 2/94 405/18639 0.00493827160493827 0.97919621749409 0.609097497734144 0.693062607361495 GO:0015276 ligand-gated monoatomic ion channel activity 1/94 186/18639 0.00537634408602151 1.06606039807824 0.611365754133441 0.693062607361495 GO:0008234 cysteine-type peptidase activity 1/94 187/18639 0.0053475935828877 1.06035954033451 0.613345465785283 0.693062607361495 GO:0022834 ligand-gated channel activity 1/94 188/18639 0.00531914893617021 1.05471933001358 0.615315199484405 0.693062607361495 GO:0016887 ATP hydrolysis activity 2/94 417/18639 0.00479616306954436 0.951017909076994 0.625070540050328 0.701518016171591 GO:0016829 lyase activity 1/94 200/18639 0.005 0.991436170212766 0.638191589985534 0.713676616758017 GO:0004674 protein serine/threonine kinase activity 2/94 433/18639 0.0046189376443418 0.915876369711562 0.645587787020823 0.719369248394631 GO:0005125 cytokine activity 1/94 234/18639 0.00427350427350427 0.847381342062193 0.695951524164507 0.735859901685962 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 1/94 243/18639 0.00411522633744856 0.815996847911742 0.709648124161488 0.735859901685962 GO:0004676 3-phosphoinositide-dependent protein kinase activity 1/94 245/18639 0.00408163265306122 0.809335649153278 0.712607907074098 0.735859901685962 GO:0004711 ribosomal protein S6 kinase activity 1/94 245/18639 0.00408163265306122 0.809335649153278 0.712607907074098 0.735859901685962 GO:0035175 histone H3S10 kinase activity 1/94 245/18639 0.00408163265306122 0.809335649153278 0.712607907074098 0.735859901685962 GO:0035979 histone H2AXS139 kinase activity 1/94 245/18639 0.00408163265306122 0.809335649153278 0.712607907074098 0.735859901685962 GO:0044022 histone H3S28 kinase activity 1/94 245/18639 0.00408163265306122 0.809335649153278 0.712607907074098 0.735859901685962 GO:0044023 histone H4S1 kinase activity 1/94 245/18639 0.00408163265306122 0.809335649153278 0.712607907074098 0.735859901685962 GO:0044024 histone H2AS1 kinase activity 1/94 245/18639 0.00408163265306122 0.809335649153278 0.712607907074098 0.735859901685962 GO:0044025 histone H2BS14 kinase activity 1/94 245/18639 0.00408163265306122 0.809335649153278 0.712607907074098 0.735859901685962 GO:0072354 histone H3T3 kinase activity 1/94 245/18639 0.00408163265306122 0.809335649153278 0.712607907074098 0.735859901685962 GO:0072371 histone H2AS121 kinase activity 1/94 245/18639 0.00408163265306122 0.809335649153278 0.712607907074098 0.735859901685962 GO:0072518 Rho-dependent protein serine/threonine kinase activity 1/94 245/18639 0.00408163265306122 0.809335649153278 0.712607907074098 0.735859901685962 GO:0140823 histone H2BS36 kinase activity 1/94 245/18639 0.00408163265306122 0.809335649153278 0.712607907074098 0.735859901685962 GO:0140855 histone H3S57 kinase activity 1/94 245/18639 0.00408163265306122 0.809335649153278 0.712607907074098 0.735859901685962 GO:0140995 histone H2A kinase activity 1/94 245/18639 0.00408163265306122 0.809335649153278 0.712607907074098 0.735859901685962 GO:0140997 histone H4 kinase activity 1/94 245/18639 0.00408163265306122 0.809335649153278 0.712607907074098 0.735859901685962 GO:0140998 histone H2B kinase activity 1/94 245/18639 0.00408163265306122 0.809335649153278 0.712607907074098 0.735859901685962 GO:1990244 histone H2AT120 kinase activity 1/94 245/18639 0.00408163265306122 0.809335649153278 0.712607907074098 0.735859901685962 GO:0004677 DNA-dependent protein kinase activity 1/94 246/18639 0.0040650406504065 0.806045666839647 0.714076584726324 0.735859901685962 GO:0140857 histone H3T45 kinase activity 1/94 246/18639 0.0040650406504065 0.806045666839647 0.714076584726324 0.735859901685962 GO:0035402 histone H3T11 kinase activity 1/94 247/18639 0.00404858299595142 0.80278232405892 0.715537836345729 0.735859901685962 GO:0035403 histone H3T6 kinase activity 1/94 247/18639 0.00404858299595142 0.80278232405892 0.715537836345729 0.735859901685962 GO:0004679 AMP-activated protein kinase activity 1/94 248/18639 0.00403225806451613 0.799545298558682 0.716991699078629 0.735859901685962 GO:0019887 protein kinase regulator activity 1/94 255/18639 0.00392156862745098 0.777596996245307 0.726964931304427 0.743649372350758 GO:0016757 glycosyltransferase activity 1/94 267/18639 0.00374531835205993 0.742648816638776 0.743259286016568 0.757832997507089 GO:0030246 carbohydrate binding 1/94 280/18639 0.00357142857142857 0.708168693009118 0.759826919182057 0.772201950439094 GO:0015291 secondary active transmembrane transporter activity 1/94 287/18639 0.00348432055749129 0.690896285862555 0.768305163779577 0.77576443721433 GO:0019207 kinase regulator activity 1/94 287/18639 0.00348432055749129 0.690896285862555 0.768305163779577 0.77576443721433 GO:0031625 ubiquitin protein ligase binding 1/94 302/18639 0.0033112582781457 0.656580245174017 0.785488495917951 0.790556163633551 GO:0044389 ubiquitin-like protein ligase binding 1/94 322/18639 0.0031055900621118 0.61579886348619 0.806452820164941 0.809045916049716 GO:0106310 protein serine kinase activity 1/94 361/18639 0.00277008310249307 0.549272116461366 0.841674177121797 0.841674177121797