category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 43/94 238/9376 18.0210978008225 RPS26/RPL37A/RPL37/RPLP2/RPL41/RPL28/RPL36A/RPS18/RPL38/RPL35A/RPL27A/UBA52/RPL27/RPL36/RPS20/RPL26/RPL13A/RPL34/RPS8/RPL23A/RPL31/RPS19/RPL35/RPL21/RPS23/RPL23/MX2/RPL17/RPS21/RPS14/RPS15/RPS12/RPS29/RPS10/TYK2/RPS28/RPL32/HBEGF/TRAF3/RPS27/RPS11/RPS25/STAT1 26.7657398024133 Genetic Information Processing Translation hsa03010 Ribosome 38/94 222/9376 17.0734138393713 RPS26/RPL37A/RPL37/RPLP2/RPL41/RPL28/RPL36A/RPS18/RPL38/RPL35A/RPL27A/UBA52/RPL27/RPL36/RPS20/RPL26/RPL13A/RPL34/RPS8/RPL23A/RPL31/RPS19/RPL35/RPL21/RPS23/RPL23/RPL17/RPS21/RPS14/RPS15/RPS12/RPS29/RPS10/RPS28/RPL32/RPS27/RPS11/RPS25 24.389783356753 Metabolism Energy metabolism hsa00190 Oxidative phosphorylation 8/94 138/9376 5.78230033919211 MT-ND3/MT-ND1/MT-ND5/MT-ND4/MT-ATP8/MT-ND2/MT-CYB/ATP5F1E 5.69529461048296 Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 9/94 205/9376 4.37903476907109 MT-ND3/MT-ND1/MT-ND5/MT-ND4/MT-ATP8/MT-ND2/MT-CYB/TGFB1/ATP5F1E 4.9225487666776 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 8/94 196/9376 4.07121146330873 UBA52/HLA-B/HLA-F/TYK2/HCK/TRAF3/STAT1/GNB1 4.37265484943557 Human Diseases Neurodegenerative disease hsa05012 Parkinson disease 9/94 268/9376 3.3496348046999 MT-ND3/MT-ND1/MT-ND5/UBA52/MT-ND4/MT-ATP8/MT-ND2/MT-CYB/ATP5F1E 3.92721823552498 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 8/94 227/9376 3.5152310432093 MT-ND3/MT-ND1/MT-ND5/MT-ND4/MT-ATP8/MT-ND2/MT-CYB/ATP5F1E 3.86040422491404 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 7/94 180/9376 3.8789598108747 ITGA5/HLA-B/HLA-F/TYK2/TRAF3/STAT1/POU2F2 3.92465202512667 Organismal Systems Environmental adaptation hsa04714 Thermogenesis 8/94 235/9376 3.39556360344047 MT-ND3/MT-ND1/MT-ND5/MT-ND4/MT-ATP8/MT-ND2/MT-CYB/ATP5F1E 3.74260131381372 Human Diseases Neurodegenerative disease hsa05016 Huntington disease 9/94 308/9376 2.91461729759602 MT-ND3/MT-ND1/MT-ND5/HIP1/MT-ND4/MT-ATP8/MT-ND2/MT-CYB/ATP5F1E 3.43819388607857 Organismal Systems Nervous system hsa04723 Retrograde endocannabinoid signaling 6/94 149/9376 4.01656432957304 MT-ND3/MT-ND1/MT-ND5/MT-ND4/MT-ND2/GNB1 3.73511732499888 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 7/94 205/9376 3.40591593149974 NCOR2/HLA-B/BTK/HLA-F/TYK2/TRAF3/STAT1 3.50491762018471 Human Diseases Neurodegenerative disease hsa05020 Prion disease 8/94 275/9376 2.90166344294004 MT-ND3/MT-ND1/MT-ND5/MT-ND4/MT-ATP8/MT-ND2/MT-CYB/ATP5F1E 3.22095183443634 Human Diseases Infectious disease: bacterial hsa05100 Bacterial invasion of epithelial cells 4/94 78/9376 5.11511183851609 DNM2/ITGA5/CRK/SEPTIN9 3.67250973882667 Human Diseases Immune disease hsa05332 Graft-versus-host disease 3/94 45/9376 6.64964539007092 KLRD1/HLA-B/HLA-F 3.82289292912125 Organismal Systems Immune system hsa04062 Chemokine signaling pathway 6/94 193/9376 3.10087090728696 VAV1/CRK/HCK/STAT1/TIAM1/GNB1 2.96766252347878 Organismal Systems Excretory system hsa04961 Endocrine and other factor-regulated calcium reabsorption 3/94 53/9376 5.64592533119229 ATP1B3/DNM2/SLC8A2 3.41319500371735 Organismal Systems Immune system hsa04666 Fc gamma R-mediated phagocytosis 4/94 98/9376 4.07121146330873 DNM2/VAV1/CRK/HCK 3.07556108274981 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 8/94 333/9376 2.39626860903457 IRF1/ITGA5/MX2/HLA-B/HLA-F/TYK2/TRAF3/STAT1 2.61073991227954 Human Diseases Infectious disease: viral hsa05160 Hepatitis C 5/94 156/9376 3.19694489907256 MX2/CLDN11/TYK2/TRAF3/STAT1 2.78448438169241 Human Diseases Neurodegenerative disease hsa05022 Pathways of neurodegeneration - multiple diseases 10/94 480/9376 2.07801418439716 MT-ND3/MT-ND1/MT-ND5/UBA52/HIP1/MT-ND4/MT-ATP8/MT-ND2/MT-CYB/ATP5F1E 2.43992507246544 Organismal Systems Digestive system hsa04978 Mineral absorption 3/94 61/9376 4.90547610742937 ATP1B3/ATOX1/SLC8A2 3.07947197499742 Human Diseases Neurodegenerative disease hsa05014 Amyotrophic lateral sclerosis 8/94 368/9376 2.16836262719704 MT-ND3/MT-ND1/MT-ND5/MT-ND4/MT-ATP8/MT-ND2/MT-CYB/ATP5F1E 2.30099757062051 Human Diseases Cardiovascular disease hsa05416 Viral myocarditis 3/94 70/9376 4.27477203647416 CD55/HLA-B/HLA-F 2.76743450887413 Human Diseases Neurodegenerative disease hsa05010 Alzheimer disease 8/94 388/9376 2.05659135775389 MT-ND3/MT-ND1/MT-ND5/MT-ND4/MT-ATP8/MT-ND2/MT-CYB/ATP5F1E 2.13904621600981 Human Diseases Infectious disease: viral hsa05162 Measles 4/94 136/9376 2.93366708385482 MX2/TYK2/TRAF3/STAT1 2.28583014598777 Organismal Systems Immune system hsa04612 Antigen processing and presentation 3/94 82/9376 3.64919564089258 KLRD1/HLA-B/HLA-F 2.42464637168816 Human Diseases Cancer: overview hsa05205 Proteoglycans in cancer 5/94 204/9376 2.44472256987902 VAV1/ITGA5/TGFB1/HBEGF/TIAM1 2.09940535754009 Organismal Systems Development and regeneration hsa04380 Osteoclast differentiation 4/94 142/9376 2.80970931974828 TGFB1/BTK/TYK2/STAT1 2.18668810745293 Organismal Systems Circulatory system hsa04260 Cardiac muscle contraction 3/94 87/9376 3.43947175348496 ATP1B3/MT-CYB/SLC8A2 2.30038073382406 Human Diseases Immune disease hsa05330 Allograft rejection 2/94 39/9376 5.11511183851609 HLA-B/HLA-F 2.59142742046878 Human Diseases Endocrine and metabolic disease hsa04940 Type I diabetes mellitus 2/94 44/9376 4.53384912959381 HLA-B/HLA-F 2.36437174309138 Human Diseases Cardiovascular disease hsa05410 Hypertrophic cardiomyopathy 3/94 99/9376 3.02256608639587 ITGA5/TGFB1/SLC8A2 2.03584787417602 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 5/94 227/9376 2.19701940200581 AKAP13/CRK/HLA-B/HLA-F/GNB1 1.83719852268967 Human Diseases Infectious disease: viral hsa05161 Hepatitis B 4/94 163/9376 2.44772222947396 TGFB1/TYK2/TRAF3/STAT1 1.87632166215751 Human Diseases Cardiovascular disease hsa05414 Dilated cardiomyopathy 3/94 105/9376 2.84984802431611 ITGA5/TGFB1/SLC8A2 1.91821018243648 Human Diseases Infectious disease: viral hsa05164 Influenza A 4/94 173/9376 2.30623539540032 MX2/TYK2/TRAF3/STAT1 1.74505279741841 Metabolism Energy metabolism hsa00920 Sulfur metabolism 1/94 10/9376 9.97446808510638 PAPSS2 2.85733014932406 Organismal Systems Immune system hsa04620 Toll-like receptor signaling pathway 3/94 109/9376 2.74526644544212 TYK2/TRAF3/STAT1 1.84431113972454 Organismal Systems Immune system hsa04659 Th17 cell differentiation 3/94 109/9376 2.74526644544212 TGFB1/TYK2/STAT1 1.84431113972454 Environmental Information Processing Signal transduction hsa04350 TGF-beta signaling pathway 3/94 110/9376 2.72030947775629 SKIL/SMAD7/TGFB1 1.82635652104988 Human Diseases Immune disease hsa05320 Autoimmune thyroid disease 2/94 54/9376 3.69424743892829 HLA-B/HLA-F 1.99806030687997 Human Diseases Infectious disease: parasitic hsa05145 Toxoplasmosis 3/94 112/9376 2.67173252279635 TGFB1/TYK2/STAT1 1.79104011307766 Cellular Processes Transport and catabolism hsa04144 Endocytosis 5/94 250/9376 1.99489361702128 FOLR3/DNM2/AGAP3/HLA-B/HLA-F 1.60448329430129 Organismal Systems Endocrine system hsa04928 Parathyroid hormone synthesis, secretion and action 3/94 115/9376 2.60203515263645 AKAP13/PDE4A/HBEGF 1.73948545786665 Metabolism Nucleotide metabolism hsa00230 Purine metabolism 3/94 128/9376 2.33776595744681 ADK/PDE4A/PAPSS2 1.53352195266224 Human Diseases Immune disease hsa05321 Inflammatory bowel disease 2/94 66/9376 3.02256608639587 TGFB1/STAT1 1.65931420509404 Organismal Systems Immune system hsa04650 Natural killer cell mediated cytotoxicity 3/94 133/9376 2.24988001919693 KLRD1/VAV1/HLA-B 1.46088642105727 Organismal Systems Immune system hsa04664 Fc epsilon RI signaling pathway 2/94 69/9376 2.89115016959605 VAV1/BTK 1.58662570993866 Human Diseases Cancer: specific types hsa05211 Renal cell carcinoma 2/94 70/9376 2.84984802431611 TGFB1/CRK 1.5632640078901 Metabolism Metabolism of other amino acids hsa00450 Selenocompound metabolism 1/94 17/9376 5.86733416770964 PAPSS2 2.02129491688539 Organismal Systems Endocrine system hsa04917 Prolactin signaling pathway 2/94 71/9376 2.80970931974828 IRF1/STAT1 1.54031161936539 Human Diseases Infectious disease: bacterial hsa05135 Yersinia infection 3/94 138/9376 2.16836262719704 VAV1/ITGA5/CRK 1.39141603450383 Environmental Information Processing Signal transduction hsa04015 Rap1 signaling pathway 4/94 212/9376 1.88197511039743 VAV1/CRK/SIPA1L1/TIAM1 1.30710508007509 Organismal Systems Digestive system hsa04980 Cobalamin transport and metabolism 1/94 18/9376 5.54137115839243 ZNF143 1.94070941411617 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 4/94 214/9376 1.86438655796381 CRK/HLA-B/HLA-F/GNB1 1.28720740793728 Human Diseases Cancer: specific types hsa05212 Pancreatic cancer 2/94 77/9376 2.59077093119646 TGFB1/STAT1 1.410469398115 Human Diseases Cancer: specific types hsa05220 Chronic myeloid leukemia 2/94 77/9376 2.59077093119646 TGFB1/CRK 1.410469398115 Human Diseases Infectious disease: bacterial hsa05133 Pertussis 2/94 78/9376 2.55755591925805 IRF1/ITGA5 1.39003252079413 Human Diseases Infectious disease: parasitic hsa05140 Leishmaniasis 2/94 78/9376 2.55755591925805 TGFB1/STAT1 1.39003252079413 Environmental Information Processing Signal transduction hsa04024 cAMP signaling pathway 4/94 226/9376 1.76539258143476 ATP1B3/VAV1/PDE4A/TIAM1 1.17207851204972 Cellular Processes Transport and catabolism hsa04145 Phagosome 3/94 155/9376 1.93054221002059 ITGA5/HLA-B/HLA-F 1.17555160516832 Cellular Processes Cell motility hsa04810 Regulation of actin cytoskeleton 4/94 232/9376 1.71973587674248 VAV1/ITGA5/CRK/TIAM1 1.11706338879108 Organismal Systems Excretory system hsa04964 Proximal tubule bicarbonate reclamation 1/94 23/9376 4.33672525439408 ATP1B3 1.61226966272917 Cellular Processes Transport and catabolism hsa04148 Efferocytosis 3/94 157/9376 1.90594931562542 PPARD/TGFB1/CRK 1.15196849799146 Cellular Processes Cell growth and death hsa04218 Cellular senescence 3/94 157/9376 1.90594931562542 TGFB1/HLA-B/HLA-F 1.15196849799146 Environmental Information Processing Signal transduction hsa04012 ErbB signaling pathway 2/94 86/9376 2.31964374072241 CRK/HBEGF 1.23716280268894 Human Diseases Cardiovascular disease hsa05412 Arrhythmogenic right ventricular cardiomyopathy 2/94 86/9376 2.31964374072241 ITGA5/SLC8A2 1.23716280268894 Environmental Information Processing Signaling molecules and interaction hsa04514 Cell adhesion molecule (CAM) interaction 3/94 160/9376 1.87021276595745 CLDN11/HLA-B/HLA-F 1.11723103518867 Organismal Systems Immune system hsa04662 B cell receptor signaling pathway 2/94 91/9376 2.19219078793547 VAV1/BTK 1.15001707011933 Human Diseases Substance dependence hsa05032 Morphine addiction 2/94 91/9376 2.19219078793547 PDE4A/GNB1 1.15001707011933 Organismal Systems Immune system hsa04658 Th1 and Th2 cell differentiation 2/94 93/9376 2.14504690002288 TYK2/STAT1 1.11673301901435 Human Diseases Infectious disease: bacterial hsa05131 Shigellosis 4/94 253/9376 1.57699100159785 UBA52/ITGA5/CRK/SEPTIN9 0.936244428625757 Organismal Systems Sensory system hsa04744 Phototransduction 1/94 29/9376 3.43947175348496 GNB1 1.323998381986 Human Diseases Drug resistance: antineoplastic hsa01523 Antifolate resistance 1/94 30/9376 3.32482269503546 FOLR3 1.2834127768906 Organismal Systems Immune system hsa04640 Hematopoietic cell lineage 2/94 100/9376 1.99489361702128 CD55/ITGA5 1.00652613839574 NA NA hsa04981 Folate transport and metabolism 1/94 31/9376 3.21757035003432 FOLR3 1.24450711327777 Human Diseases Endocrine and metabolic disease hsa04933 AGE-RAGE signaling pathway in diabetic complications 2/94 101/9376 1.97514219507057 TGFB1/STAT1 0.991517673485181 Organismal Systems Digestive system hsa04974 Protein digestion and absorption 2/94 103/9376 1.93678991943813 ATP1B3/SLC8A2 0.962009751164657 Environmental Information Processing Signal transduction hsa04064 NF-kappa B signaling pathway 2/94 105/9376 1.89989868287741 BTK/TRAF3 0.933154937035864 Cellular Processes Transport and catabolism hsa04137 Mitophagy - animal 2/94 105/9376 1.89989868287741 UBA52/TOMM7 0.933154937035864 Organismal Systems Immune system hsa04625 C-type lectin receptor signaling pathway 2/94 105/9376 1.89989868287741 IRF1/STAT1 0.933154937035864 Organismal Systems Immune system hsa04621 NOD-like receptor signaling pathway 3/94 187/9376 1.60018204573899 TYK2/TRAF3/STAT1 0.834254311799626 Organismal Systems Excretory system hsa04960 Aldosterone-regulated sodium reabsorption 1/94 38/9376 2.62486002239642 ATP1B3 1.00997261917623 Human Diseases Immune disease hsa05340 Primary immunodeficiency 1/94 38/9376 2.62486002239642 BTK 1.00997261917623 Organismal Systems Immune system hsa04670 Leukocyte transendothelial migration 2/94 116/9376 1.71973587674248 VAV1/CLDN11 0.784920073371706 Metabolism Metabolism of cofactors and vitamins hsa00670 One carbon pool by folate 1/94 39/9376 2.55755591925805 MTHFD1L 0.980846518021789 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 3/94 203/9376 1.47405932292213 VAV1/ITGA5/CRK 0.687153554036318 Environmental Information Processing Signal transduction hsa04668 TNF signaling pathway 2/94 119/9376 1.67638119077418 IRF1/TRAF3 0.747237491367934 Human Diseases Cancer: overview hsa05203 Viral carcinogenesis 3/94 205/9376 1.45967825635703 HLA-B/HLA-F/TRAF3 0.669655327198916 Human Diseases Cancer: specific types hsa05219 Bladder cancer 1/94 41/9376 2.43279709392839 HBEGF 0.92522688129807 Organismal Systems Endocrine system hsa04919 Thyroid hormone signaling pathway 2/94 122/9376 1.63515870247646 ATP1B3/STAT1 0.71060163688771 Organismal Systems Endocrine system hsa04935 Growth hormone synthesis, secretion and action 2/94 122/9376 1.63515870247646 CRK/STAT1 0.71060163688771 Genetic Information Processing Replication and repair hsa03410 Base excision repair 1/94 44/9376 2.26692456479691 POLG2 0.847653799520992 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 3/94 216/9376 1.38534278959811 VAV1/TRAF3/POU2F2 0.576574138455541 Organismal Systems Endocrine system hsa04926 Relaxin signaling pathway 2/94 130/9376 1.53453355155483 TGFB1/GNB1 0.617587482143028 NA NA hsa03272 Virion - Hepatitis viruses 1/94 48/9376 2.07801418439716 CLDN11 0.753493670020963 Organismal Systems Digestive system hsa04973 Carbohydrate digestion and absorption 1/94 48/9376 2.07801418439716 ATP1B3 0.753493670020963 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 3/94 224/9376 1.33586626139818 TGFB1/HLA-B/HLA-F 0.511989632057126 Organismal Systems Immune system hsa04672 Intestinal immune network for IgA production 1/94 50/9376 1.99489361702128 TGFB1 0.709810997972872 Human Diseases Infectious disease: parasitic hsa05144 Malaria 1/94 50/9376 1.99489361702128 TGFB1 0.709810997972872 Environmental Information Processing Signal transduction hsa04371 Apelin signaling pathway 2/94 140/9376 1.42492401215805 SLC8A2/GNB1 0.509755725178719 Genetic Information Processing Folding, sorting and degradation hsa04120 Ubiquitin mediated proteolysis 2/94 142/9376 1.40485465987414 UBA52/FBXW7 0.489189540183625 Cellular Processes Cellular community - eukaryotes hsa04550 Signaling pathways regulating pluripotency of stem cells 2/94 144/9376 1.38534278959811 SKIL/JARID2 0.468931458015807 Organismal Systems Circulatory system hsa04261 Adrenergic signaling in cardiomyocytes 2/94 154/9376 1.29538546559823 ATP1B3/SLC8A2 0.371933850758925 NA NA hsa04518 Integrin signaling 2/94 154/9376 1.29538546559823 ITGA5/TGFB1 0.371933850758925 Environmental Information Processing Signal transduction hsa04330 Notch signaling pathway 1/94 62/9376 1.60878517501716 NCOR2 0.483972381707961 Environmental Information Processing Signal transduction hsa04390 Hippo signaling pathway 2/94 157/9376 1.27063287708362 SMAD7/TGFB1 0.344125817575011 Human Diseases Endocrine and metabolic disease hsa04932 Non-alcoholic fatty liver disease 2/94 157/9376 1.27063287708362 MT-CYB/TGFB1 0.344125817575011 Cellular Processes Cell growth and death hsa04110 Cell cycle 2/94 158/9376 1.26259089684891 TFDP2/TGFB1 0.334979817027135 Human Diseases Cancer: specific types hsa05221 Acute myeloid leukemia 1/94 68/9376 1.46683354192741 PPARD 0.38879180702216 Environmental Information Processing Signal transduction hsa04022 cGMP-PKG signaling pathway 2/94 166/9376 1.2017431427839 ATP1B3/SLC8A2 0.263907537247585 Cellular Processes Cell growth and death hsa04217 Necroptosis 2/94 168/9376 1.18743667679838 TYK2/STAT1 0.246692158085773 Environmental Information Processing Signal transduction hsa04630 JAK-STAT signaling pathway 2/94 168/9376 1.18743667679838 TYK2/STAT1 0.246692158085773 Cellular Processes Cellular community - eukaryotes hsa04530 Tight junction 2/94 170/9376 1.17346683354193 CLDN11/TIAM1 0.229685833291289 Human Diseases Infectious disease: bacterial hsa05120 Epithelial cell signaling in Helicobacter pylori infection 1/94 71/9376 1.40485465987414 HBEGF 0.344587017347681 Organismal Systems Immune system hsa04622 RIG-I-like receptor signaling pathway 1/94 72/9376 1.38534278959811 TRAF3 0.330299120547166 Genetic Information Processing Information processing in viruses hsa03250 Viral life cycle - HIV-1 1/94 73/9376 1.36636549111046 MX2 0.316222859962141 Organismal Systems Endocrine system hsa04918 Thyroid hormone synthesis 1/94 75/9376 1.32992907801418 ATP1B3 0.288678995785362 Organismal Systems Endocrine system hsa03320 PPAR signaling pathway 1/94 76/9376 1.31243001119821 PPARD 0.275198998574906 Organismal Systems Digestive system hsa04971 Gastric acid secretion 1/94 76/9376 1.31243001119821 ATP1B3 0.275198998574906 Human Diseases Infectious disease: bacterial hsa05152 Tuberculosis 2/94 181/9376 1.10215116962501 TGFB1/STAT1 0.139648265927547 Organismal Systems Nervous system hsa04721 Synaptic vesicle cycle 1/94 79/9376 1.26259089684891 DNM2 0.235857982650972 Genetic Information Processing Chromosome hsa03083 Polycomb repressive complex 1/94 83/9376 1.2017431427839 JARID2 0.185775587165615 Metabolism Global and overview maps hsa01232 Nucleotide metabolism 1/94 85/9376 1.17346683354193 ADK 0.161667777042501 Organismal Systems Endocrine system hsa04911 Insulin secretion 1/94 86/9376 1.15982187036121 ATP1B3 0.149832615398773 Cellular Processes Cell motility hsa04814 Motor proteins 2/94 194/9376 1.02829567887695 MYO1C/MYO9B 0.0400757004536257 Human Diseases Cancer: specific types hsa05210 Colorectal cancer 1/94 87/9376 1.14649058449499 TGFB1 0.138138151334397 Organismal Systems Immune system hsa04610 Complement and coagulation cascades 1/94 88/9376 1.13346228239845 CD55 0.126580720486271 Environmental Information Processing Signaling molecules and interaction hsa04512 ECM-receptor interaction 1/94 89/9376 1.12072675113555 ITGA5 0.115156797065275 Organismal Systems Nervous system hsa04727 GABAergic synapse 1/94 89/9376 1.12072675113555 GNB1 0.115156797065275 Organismal Systems Digestive system hsa04976 Bile secretion 1/94 90/9376 1.10827423167849 ATP1B3 0.103862987074083 Human Diseases Cancer: overview hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer 1/94 90/9376 1.10827423167849 STAT1 0.103862987074083 Human Diseases Infectious disease: bacterial hsa05130 Pathogenic Escherichia coli infection 2/94 200/9376 0.997446808510638 MYO1C/CLDN11 -0.00367282694979139 Organismal Systems Endocrine system hsa04912 GnRH signaling pathway 1/94 93/9376 1.07252345001144 HBEGF 0.0707301432622474 Organismal Systems Digestive system hsa04970 Salivary secretion 1/94 93/9376 1.07252345001144 ATP1B3 0.0707301432622474 Human Diseases Cancer: specific types hsa05222 Small cell lung cancer 1/94 93/9376 1.07252345001144 TRAF3 0.0707301432622474 Organismal Systems Immune system hsa04657 IL-17 signaling pathway 1/94 94/9376 1.06111362607515 TRAF3 0.0599252673600702 Human Diseases Immune disease hsa05323 Rheumatoid arthritis 1/94 95/9376 1.04994400895857 TGFB1 0.049235301200377 Organismal Systems Environmental adaptation hsa04713 Circadian entrainment 1/94 97/9376 1.02829567887695 GNB1 0.0281892928129143 Organismal Systems Endocrine system hsa04925 Aldosterone synthesis and secretion 1/94 98/9376 1.01780286582718 ATP1B3 0.0178280792298518 Human Diseases Drug resistance: antineoplastic hsa01522 Endocrine resistance 1/94 99/9376 1.00752202879862 HBEGF 0.00757142446032952 Human Diseases Cancer: overview hsa05206 MicroRNAs in cancer 3/94 323/9376 0.926421184375206 ITGA5/CRK/FOXP1 -0.135421174717867 Organismal Systems Digestive system hsa04972 Pancreatic secretion 1/94 102/9376 0.977889027951606 ATP1B3 -0.0225945220317092 Human Diseases Infectious disease: parasitic hsa05142 Chagas disease 1/94 103/9376 0.968394959719066 TGFB1 -0.0324558967868121 Human Diseases Infectious disease: parasitic hsa05146 Amoebiasis 1/94 103/9376 0.968394959719066 TGFB1 -0.0324558967868121 Human Diseases Cancer: specific types hsa05215 Prostate cancer 1/94 106/9376 0.940987555198715 FOLR3 -0.0614873046426597 Cellular Processes Cell motility hsa04820 Cytoskeleton in muscle cells 2/94 233/9376 0.856177518034883 ATP1B3/ITGA5 -0.223711939372025 Organismal Systems Nervous system hsa04725 Cholinergic synapse 1/94 115/9376 0.867345050878816 GNB1 -0.144036386798752 Organismal Systems Nervous system hsa04726 Serotonergic synapse 1/94 115/9376 0.867345050878816 GNB1 -0.144036386798752 Organismal Systems Nervous system hsa04724 Glutamatergic synapse 1/94 116/9376 0.85986793837124 GNB1 -0.152823378199792 Environmental Information Processing Signal transduction hsa04014 Ras signaling pathway 2/94 238/9376 0.838190595387091 TIAM1/GNB1 -0.254445892511309 Genetic Information Processing Chromosome hsa03082 ATP-dependent chromatin remodeling 1/94 117/9376 0.852518639752682 BAZ2B -0.161538782865978 Organismal Systems Nervous system hsa04722 Neurotrophin signaling pathway 1/94 120/9376 0.831205673758865 CRK -0.187268864607342 Organismal Systems Immune system hsa04660 T cell receptor signaling pathway 1/94 122/9376 0.817579351238228 VAV1 -0.20408822410339 Organismal Systems Immune system hsa04611 Platelet activation 1/94 126/9376 0.791624451198919 BTK -0.236968132403601 Environmental Information Processing Signal transduction hsa04068 FoxO signaling pathway 1/94 133/9376 0.749960006398976 TGFB1 -0.292252076809485 Organismal Systems Nervous system hsa04728 Dopaminergic synapse 1/94 133/9376 0.749960006398976 GNB1 -0.292252076809485 Organismal Systems Endocrine system hsa04910 Insulin signaling pathway 1/94 138/9376 0.722787542399013 CRK -0.330135395887819 Organismal Systems Endocrine system hsa04915 Estrogen signaling pathway 1/94 139/9376 0.717587632022042 HBEGF -0.337562677958167 Human Diseases Endocrine and metabolic disease hsa04936 Alcoholic liver disease 1/94 144/9376 0.692671394799054 TRAF3 -0.373994414368435 Environmental Information Processing Signal transduction hsa04072 Phospholipase D signaling pathway 1/94 149/9376 0.669427388262173 DNM2 -0.409315815733605 Human Diseases Cancer: specific types hsa05226 Gastric cancer 1/94 150/9376 0.664964539007092 TGFB1 -0.416254041924286 Metabolism Global and overview maps hsa01240 Biosynthesis of cofactors 1/94 154/9376 0.647692732799116 MTHFD1L -0.443606791129682 NA NA hsa04517 IgSF CAM signaling 2/94 299/9376 0.667188500676012 VAV1/ITGA5 -0.588561070632252 Environmental Information Processing Signal transduction hsa04010 MAPK signaling pathway 2/94 300/9376 0.664964539007092 TGFB1/CRK -0.593516699494218 Cellular Processes Transport and catabolism hsa04140 Autophagy - animal 1/94 169/9376 0.590205212136472 UBA52 -0.540977863066474 Human Diseases Cancer: specific types hsa05225 Hepatocellular carcinoma 1/94 170/9376 0.586733416770964 TGFB1 -0.547202468634802 Environmental Information Processing Signal transduction hsa04310 Wnt signaling pathway 1/94 178/9376 0.560363375567774 PPARD -0.595917234953165 Human Diseases Substance dependence hsa05034 Alcoholism 1/94 191/9376 0.522223459953214 GNB1 -0.671321733454398 NA NA hsa04082 Neuroactive ligand signaling 1/94 199/9376 0.501229552015396 GNB1 -0.715658228451661 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 2/94 362/9376 0.551075584812507 ITGA5/GNB1 -0.876592028400994 NA NA hsa04382 Cornified envelope formation 1/94 217/9376 0.45965290714776 CLDN11 -0.810414941809024 NA NA hsa04081 Hormone signaling 1/94 219/9376 0.455455163703488 GNB1 -0.820555342490709 NA NA hsa04519 Cadherin signaling 2/94 404/9376 0.493785548767643 VAV1/MYO1C -1.04666902559157 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 1/94 248/9376 0.40219629375429 DNM2 -0.96011976664736 Environmental Information Processing Signal transduction hsa04020 Calcium signaling pathway 1/94 254/9376 0.392695593901826 SLC8A2 -0.987431640559692 Organismal Systems Sensory system hsa04740 Olfactory transduction 2/94 449/9376 0.444297019381131 SLC8A2/GNB1 -1.21434450596254 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 1/94 298/9376 0.334713694131087 TGFB1 -1.17449293827267