ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 51/129 175/18639 0.291428571428571 42.1080398671096 2.19056045625953e-71 6.1116636729641e-69 GO:1990948 ubiquitin ligase inhibitor activity 4/129 11/18639 0.363636363636364 52.5412262156448 6.95966771655111e-07 9.7087364645888e-05 GO:0055105 ubiquitin-protein transferase inhibitor activity 4/129 15/18639 0.266666666666667 38.5302325581395 2.81756818181845e-06 0.000262033840909116 GO:0019843 rRNA binding 6/129 65/18639 0.0923076923076923 13.3373881932021 5.78117178034279e-06 0.000403236731678909 GO:0097371 MDM2/MDM4 family protein binding 3/129 12/18639 0.25 36.1220930232558 6.80740169279755e-05 0.00379853014458104 GO:0055106 ubiquitin-protein transferase regulator activity 4/129 36/18639 0.111111111111111 16.0542635658915 0.000108645217643427 0.00483593722393387 GO:0031386 protein tag activity 3/129 15/18639 0.2 28.8976744186047 0.000138664866636097 0.00483593722393387 GO:0141047 molecular tag activity 3/129 15/18639 0.2 28.8976744186047 0.000138664866636097 0.00483593722393387 GO:0048027 mRNA 5'-UTR binding 3/129 24/18639 0.125 18.0610465116279 0.000589373733910721 0.0182705857512323 GO:0045296 cadherin binding 8/129 334/18639 0.0239520958083832 3.46079933156942 0.0022827812515569 0.0636895969184375 GO:0017166 vinculin binding 2/129 12/18639 0.166666666666667 24.0813953488372 0.00299774357195268 0.0760336778704361 GO:0043560 insulin receptor substrate binding 2/129 13/18639 0.153846153846154 22.2289803220036 0.00352677900700499 0.0819976119128661 GO:0009055 electron transfer activity 4/129 116/18639 0.0344827586206897 4.98235765838011 0.0086381472544297 0.185387929537376 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 6/129 268/18639 0.0223880597014925 3.23481430059007 0.0109325503739724 0.203379318889716 GO:0017134 fibroblast growth factor binding 2/129 23/18639 0.0869565217391304 12.5642062689585 0.0109343719833181 0.203379318889716 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 3/129 68/18639 0.0441176470588235 6.37448700410397 0.0117026317721072 0.204064641526119 GO:0001217 DNA-binding transcription repressor activity 6/129 278/18639 0.0215827338129496 3.11845407395014 0.0129134750584188 0.21193291419405 GO:0070412 R-SMAD binding 2/129 26/18639 0.0769230769230769 11.1144901610018 0.0138578068633257 0.214796006381549 GO:0001671 ATPase activator activity 2/129 27/18639 0.0740740740740741 10.702842377261 0.014899316861078 0.218784705486356 GO:0031625 ubiquitin protein ligase binding 6/129 302/18639 0.0198675496688742 2.87062990913291 0.01867086792705 0.260458607582347 GO:0140311 protein sequestering activity 2/129 33/18639 0.0606060606060606 8.7568710359408 0.0218174740954282 0.289860727267832 GO:0044389 ubiquitin-like protein ligase binding 6/129 322/18639 0.0186335403726708 2.69232991477683 0.0246490923655169 0.312595307726328 GO:0008137 NADH dehydrogenase (ubiquinone) activity 2/129 41/18639 0.0487804878048781 7.0482132728304 0.0326934244489649 0.380061059219217 GO:0140318 protein transporter activity 2/129 41/18639 0.0487804878048781 7.0482132728304 0.0326934244489649 0.380061059219217 GO:0003954 NADH dehydrogenase activity 2/129 44/18639 0.0454545454545455 6.5676532769556 0.0372163919948255 0.415334934662253 GO:0015078 proton transmembrane transporter activity 4/129 185/18639 0.0216216216216216 3.12407291011942 0.0397525475874396 0.426575414495986 GO:0060590 ATPase regulator activity 2/129 49/18639 0.0408163265306122 5.89748457522544 0.0452480734164036 0.467563425302837 GO:0022853 active monoatomic ion transmembrane transporter activity 3/129 118/18639 0.0254237288135593 3.67343318880568 0.0486896310725663 0.485157395330215 GO:0140313 molecular sequestering activity 2/129 55/18639 0.0363636363636364 5.25412262156448 0.0556384863503903 0.521307305083748 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 2/129 58/18639 0.0344827586206897 4.98235765838011 0.0611173840864157 0.521307305083748 GO:0005131 growth hormone receptor binding 1/129 10/18639 0.1 14.4488372093023 0.0671092338627352 0.521307305083748 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/129 10/18639 0.1 14.4488372093023 0.0671092338627352 0.521307305083748 GO:0016783 sulfurtransferase activity 1/129 10/18639 0.1 14.4488372093023 0.0671092338627352 0.521307305083748 GO:0031996 thioesterase binding 1/129 10/18639 0.1 14.4488372093023 0.0671092338627352 0.521307305083748 GO:0019838 growth factor binding 3/129 136/18639 0.0220588235294118 3.18724350205198 0.0685087726200872 0.521307305083748 GO:0030295 protein kinase activator activity 3/129 139/18639 0.0215827338129496 3.11845407395014 0.0721192069908298 0.521307305083748 GO:0019206 nucleoside kinase activity 1/129 11/18639 0.0909090909090909 13.1353065539112 0.0735692107177305 0.521307305083748 GO:0019215 intermediate filament binding 1/129 11/18639 0.0909090909090909 13.1353065539112 0.0735692107177305 0.521307305083748 GO:0015368 calcium:monoatomic cation antiporter activity 1/129 12/18639 0.0833333333333333 12.0406976744186 0.0799847986400738 0.521307305083748 GO:0034452 dynactin binding 1/129 12/18639 0.0833333333333333 12.0406976744186 0.0799847986400738 0.521307305083748 GO:0070679 inositol 1,4,5 trisphosphate binding 1/129 12/18639 0.0833333333333333 12.0406976744186 0.0799847986400738 0.521307305083748 GO:0019209 kinase activator activity 3/129 148/18639 0.0202702702702703 2.92881835323696 0.0834477676813352 0.521307305083748 GO:0019104 DNA N-glycosylase activity 1/129 13/18639 0.0769230769230769 11.1144901610018 0.0863563002761629 0.521307305083748 GO:0031994 insulin-like growth factor I binding 1/129 13/18639 0.0769230769230769 11.1144901610018 0.0863563002761629 0.521307305083748 GO:0003779 actin binding 6/129 443/18639 0.0135440180586907 1.95695312089873 0.0875528802797774 0.521307305083748 GO:0005545 1-phosphatidylinositol binding 1/129 14/18639 0.0714285714285714 10.3205980066445 0.0926840162250716 0.521307305083748 GO:0030983 mismatched DNA binding 1/129 14/18639 0.0714285714285714 10.3205980066445 0.0926840162250716 0.521307305083748 GO:0031404 chloride ion binding 1/129 14/18639 0.0714285714285714 10.3205980066445 0.0926840162250716 0.521307305083748 GO:0004129 cytochrome-c oxidase activity 1/129 15/18639 0.0666666666666667 9.63255813953488 0.0989682450522911 0.521307305083748 GO:0141003 histone H2AX kinase activity 5/129 354/18639 0.0141242937853107 2.04079621600315 0.0996097299764574 0.521307305083748 GO:0140996 histone H3 kinase activity 5/129 357/18639 0.0140056022408964 2.02364666796951 0.10230103758288 0.521307305083748 GO:0046332 SMAD binding 2/129 79/18639 0.0253164556962025 3.65793347070945 0.103888623761506 0.521307305083748 GO:0035173 histone kinase activity 5/129 360/18639 0.0138888888888889 2.00678294573643 0.105028613349762 0.521307305083748 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/129 16/18639 0.0625 9.03052325581395 0.105209283303379 0.521307305083748 GO:0015399 primary active transmembrane transporter activity 3/129 166/18639 0.0180722891566265 2.61123564023536 0.108195024768703 0.521307305083748 GO:0015278 intracellularly gated calcium channel activity 1/129 17/18639 0.0588235294117647 8.49931600547196 0.111407425517515 0.521307305083748 GO:0032183 SUMO binding 1/129 17/18639 0.0588235294117647 8.49931600547196 0.111407425517515 0.521307305083748 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/129 18/18639 0.0555555555555556 8.02713178294574 0.117562964240973 0.521307305083748 GO:0005520 insulin-like growth factor binding 1/129 19/18639 0.0526315789473684 7.6046511627907 0.123676190040496 0.521307305083748 GO:0022821 solute:potassium antiporter activity 1/129 19/18639 0.0526315789473684 7.6046511627907 0.123676190040496 0.521307305083748 GO:0031420 alkali metal ion binding 1/129 19/18639 0.0526315789473684 7.6046511627907 0.123676190040496 0.521307305083748 GO:0016651 oxidoreductase activity, acting on NAD(P)H 2/129 88/18639 0.0227272727272727 3.2838266384778 0.12412290872043 0.521307305083748 GO:0043178 alcohol binding 2/129 92/18639 0.0217391304347826 3.14105156723964 0.133399798837995 0.521307305083748 GO:0031267 small GTPase binding 4/129 283/18639 0.0141342756183746 2.04223847481305 0.1334255542947 0.521307305083748 GO:0035091 phosphatidylinositol binding 4/129 284/18639 0.0140845070422535 2.03504749426793 0.134651214913021 0.521307305083748 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/129 21/18639 0.0476190476190476 6.88039867109635 0.135776855316701 0.521307305083748 GO:0005158 insulin receptor binding 1/129 23/18639 0.0434782608695652 6.28210313447927 0.147711706792244 0.521307305083748 GO:0043274 phospholipase binding 1/129 23/18639 0.0434782608695652 6.28210313447927 0.147711706792244 0.521307305083748 GO:0140103 catalytic activity, acting on a glycoprotein 1/129 23/18639 0.0434782608695652 6.28210313447927 0.147711706792244 0.521307305083748 GO:0050699 WW domain binding 1/129 24/18639 0.0416666666666667 6.0203488372093 0.153617658114966 0.521307305083748 GO:0004857 enzyme inhibitor activity 5/129 416/18639 0.0120192307692308 1.73663908765653 0.162157749837837 0.521307305083748 GO:0005112 Notch binding 1/129 26/18639 0.0384615384615385 5.55724508050089 0.165308006770849 0.521307305083748 GO:0030507 spectrin binding 1/129 26/18639 0.0384615384615385 5.55724508050089 0.165308006770849 0.521307305083748 GO:0043548 phosphatidylinositol 3-kinase binding 1/129 26/18639 0.0384615384615385 5.55724508050089 0.165308006770849 0.521307305083748 GO:0052742 phosphatidylinositol kinase activity 1/129 26/18639 0.0384615384615385 5.55724508050089 0.165308006770849 0.521307305083748 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/129 27/18639 0.037037037037037 5.35142118863049 0.171092956382764 0.521307305083748 GO:0008320 protein transmembrane transporter activity 1/129 27/18639 0.037037037037037 5.35142118863049 0.171092956382764 0.521307305083748 GO:0015252 proton channel activity 1/129 27/18639 0.037037037037037 5.35142118863049 0.171092956382764 0.521307305083748 GO:0051020 GTPase binding 4/129 315/18639 0.0126984126984127 1.83477297895903 0.174804293119885 0.521307305083748 GO:0046875 ephrin receptor binding 1/129 28/18639 0.0357142857142857 5.16029900332226 0.17683812125632 0.521307305083748 GO:0051959 dynein light intermediate chain binding 1/129 28/18639 0.0357142857142857 5.16029900332226 0.17683812125632 0.521307305083748 GO:0005200 structural constituent of cytoskeleton 2/129 112/18639 0.0178571428571429 2.58014950166113 0.181771095232794 0.521307305083748 GO:0003785 actin monomer binding 1/129 29/18639 0.0344827586206897 4.98235765838011 0.182543772879442 0.521307305083748 GO:0099604 ligand-gated calcium channel activity 1/129 29/18639 0.0344827586206897 4.98235765838011 0.182543772879442 0.521307305083748 GO:0001965 G-protein alpha-subunit binding 1/129 30/18639 0.0333333333333333 4.81627906976744 0.188210180901933 0.521307305083748 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 1/129 30/18639 0.0333333333333333 4.81627906976744 0.188210180901933 0.521307305083748 GO:0098918 structural constituent of synapse 1/129 30/18639 0.0333333333333333 4.81627906976744 0.188210180901933 0.521307305083748 GO:0035401 histone H3Y41 kinase activity 2/129 115/18639 0.0173913043478261 2.51284125379171 0.189245474202625 0.521307305083748 GO:0140801 histone H2AXY142 kinase activity 2/129 115/18639 0.0173913043478261 2.51284125379171 0.189245474202625 0.521307305083748 GO:0005164 tumor necrosis factor receptor binding 1/129 31/18639 0.032258064516129 4.6609152288072 0.193837613147817 0.521307305083748 GO:0070273 phosphatidylinositol-4-phosphate binding 1/129 31/18639 0.032258064516129 4.6609152288072 0.193837613147817 0.521307305083748 GO:0022884 macromolecule transmembrane transporter activity 1/129 32/18639 0.03125 4.51526162790698 0.199426335627607 0.521307305083748 GO:0030296 protein tyrosine kinase activator activity 1/129 33/18639 0.0303030303030303 4.3784355179704 0.204976612550487 0.521307305083748 GO:0051427 hormone receptor binding 1/129 34/18639 0.0294117647058824 4.24965800273598 0.210488706336416 0.521307305083748 GO:0005261 monoatomic cation channel activity 4/129 341/18639 0.0117302052785924 1.6948782650208 0.211258269341678 0.521307305083748 GO:0043015 gamma-tubulin binding 1/129 35/18639 0.0285714285714286 4.12823920265781 0.215962877628144 0.521307305083748 GO:0042805 actinin binding 1/129 37/18639 0.027027027027027 3.90509113764928 0.226798486485542 0.521307305083748 GO:0005262 calcium channel activity 2/129 131/18639 0.0152671755725191 2.20592934493165 0.229698562703782 0.521307305083748 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 3/129 243/18639 0.0123456790123457 1.78380706287683 0.237117802129542 0.521307305083748 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/129 39/18639 0.0256410256410256 3.70483005366726 0.237485489172352 0.521307305083748 GO:0106310 protein serine kinase activity 4/129 361/18639 0.0110803324099723 1.60097919216646 0.240645027440951 0.521307305083748 GO:0004676 3-phosphoinositide-dependent protein kinase activity 3/129 245/18639 0.0122448979591837 1.76924537256763 0.240794348522393 0.521307305083748 GO:0004711 ribosomal protein S6 kinase activity 3/129 245/18639 0.0122448979591837 1.76924537256763 0.240794348522393 0.521307305083748 GO:0035175 histone H3S10 kinase activity 3/129 245/18639 0.0122448979591837 1.76924537256763 0.240794348522393 0.521307305083748 GO:0035979 histone H2AXS139 kinase activity 3/129 245/18639 0.0122448979591837 1.76924537256763 0.240794348522393 0.521307305083748 GO:0044022 histone H3S28 kinase activity 3/129 245/18639 0.0122448979591837 1.76924537256763 0.240794348522393 0.521307305083748 GO:0044023 histone H4S1 kinase activity 3/129 245/18639 0.0122448979591837 1.76924537256763 0.240794348522393 0.521307305083748 GO:0044024 histone H2AS1 kinase activity 3/129 245/18639 0.0122448979591837 1.76924537256763 0.240794348522393 0.521307305083748 GO:0044025 histone H2BS14 kinase activity 3/129 245/18639 0.0122448979591837 1.76924537256763 0.240794348522393 0.521307305083748 GO:0072354 histone H3T3 kinase activity 3/129 245/18639 0.0122448979591837 1.76924537256763 0.240794348522393 0.521307305083748 GO:0072371 histone H2AS121 kinase activity 3/129 245/18639 0.0122448979591837 1.76924537256763 0.240794348522393 0.521307305083748 GO:0072518 Rho-dependent protein serine/threonine kinase activity 3/129 245/18639 0.0122448979591837 1.76924537256763 0.240794348522393 0.521307305083748 GO:0140823 histone H2BS36 kinase activity 3/129 245/18639 0.0122448979591837 1.76924537256763 0.240794348522393 0.521307305083748 GO:0140855 histone H3S57 kinase activity 3/129 245/18639 0.0122448979591837 1.76924537256763 0.240794348522393 0.521307305083748 GO:0140995 histone H2A kinase activity 3/129 245/18639 0.0122448979591837 1.76924537256763 0.240794348522393 0.521307305083748 GO:0140997 histone H4 kinase activity 3/129 245/18639 0.0122448979591837 1.76924537256763 0.240794348522393 0.521307305083748 GO:0140998 histone H2B kinase activity 3/129 245/18639 0.0122448979591837 1.76924537256763 0.240794348522393 0.521307305083748 GO:1990244 histone H2AT120 kinase activity 3/129 245/18639 0.0122448979591837 1.76924537256763 0.240794348522393 0.521307305083748 GO:0004677 DNA-dependent protein kinase activity 3/129 246/18639 0.0121951219512195 1.7620533182076 0.242636304762861 0.521307305083748 GO:0140857 histone H3T45 kinase activity 3/129 246/18639 0.0121951219512195 1.7620533182076 0.242636304762861 0.521307305083748 GO:0035402 histone H3T11 kinase activity 3/129 247/18639 0.0121457489878543 1.75491949910555 0.244480637381065 0.521307305083748 GO:0035403 histone H3T6 kinase activity 3/129 247/18639 0.0121457489878543 1.75491949910555 0.244480637381065 0.521307305083748 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 5/129 484/18639 0.0103305785123967 1.49264847203536 0.244488430515264 0.521307305083748 GO:0004679 AMP-activated protein kinase activity 3/129 248/18639 0.0120967741935484 1.7478432108027 0.246327287468995 0.521307305083748 GO:0001727 lipid kinase activity 1/129 41/18639 0.024390243902439 3.5241066364152 0.248025908058941 0.521307305083748 GO:0140828 metal cation:monoatomic cation antiporter activity 1/129 41/18639 0.024390243902439 3.5241066364152 0.248025908058941 0.521307305083748 GO:0004713 protein tyrosine kinase activity 2/129 140/18639 0.0142857142857143 2.0641196013289 0.252719248938288 0.521307305083748 GO:0008307 structural constituent of muscle 1/129 42/18639 0.0238095238095238 3.44019933554817 0.253241773090687 0.521307305083748 GO:0001216 DNA-binding transcription activator activity 5/129 491/18639 0.010183299389002 1.47136835125278 0.253558122732446 0.521307305083748 GO:0008375 acetylglucosaminyltransferase activity 1/129 43/18639 0.0232558139534884 3.36019469983775 0.258421738207173 0.521307305083748 GO:0019887 protein kinase regulator activity 3/129 255/18639 0.0117647058823529 1.69986320109439 0.259313835546139 0.521307305083748 GO:0019903 protein phosphatase binding 2/129 144/18639 0.0138888888888889 2.00678294573643 0.26297526952802 0.521307305083748 GO:0001223 transcription coactivator binding 1/129 44/18639 0.0227272727272727 3.2838266384778 0.263566048584205 0.521307305083748 GO:0019205 nucleobase-containing compound kinase activity 1/129 44/18639 0.0227272727272727 3.2838266384778 0.263566048584205 0.521307305083748 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/129 45/18639 0.0222222222222222 3.21085271317829 0.268674947736269 0.521307305083748 GO:0042605 peptide antigen binding 1/129 45/18639 0.0222222222222222 3.21085271317829 0.268674947736269 0.521307305083748 GO:0015085 calcium ion transmembrane transporter activity 2/129 147/18639 0.0136054421768707 1.96582819174181 0.270669849805775 0.521307305083748 GO:0043495 protein-membrane adaptor activity 1/129 47/18639 0.0212765957446809 3.07422068283028 0.278787478183812 0.521307305083748 GO:0032266 phosphatidylinositol-3-phosphate binding 1/129 48/18639 0.0208333333333333 3.01017441860465 0.283791588301834 0.521307305083748 GO:0005004 GPI-linked ephrin receptor activity 1/129 49/18639 0.0204081632653061 2.94874228761272 0.288761244861948 0.521307305083748 GO:0005008 hepatocyte growth factor receptor activity 1/129 49/18639 0.0204081632653061 2.94874228761272 0.288761244861948 0.521307305083748 GO:0005009 insulin receptor activity 1/129 49/18639 0.0204081632653061 2.94874228761272 0.288761244861948 0.521307305083748 GO:0005011 macrophage colony-stimulating factor receptor activity 1/129 49/18639 0.0204081632653061 2.94874228761272 0.288761244861948 0.521307305083748 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/129 49/18639 0.0204081632653061 2.94874228761272 0.288761244861948 0.521307305083748 GO:0005020 stem cell factor receptor activity 1/129 49/18639 0.0204081632653061 2.94874228761272 0.288761244861948 0.521307305083748 GO:0008288 boss receptor activity 1/129 49/18639 0.0204081632653061 2.94874228761272 0.288761244861948 0.521307305083748 GO:0036332 placental growth factor receptor activity 1/129 49/18639 0.0204081632653061 2.94874228761272 0.288761244861948 0.521307305083748 GO:0038062 protein tyrosine kinase collagen receptor activity 1/129 49/18639 0.0204081632653061 2.94874228761272 0.288761244861948 0.521307305083748 GO:0060175 brain-derived neurotrophic factor receptor activity 1/129 49/18639 0.0204081632653061 2.94874228761272 0.288761244861948 0.521307305083748 GO:0005096 GTPase activator activity 3/129 271/18639 0.011070110701107 1.59950227409251 0.289308485247493 0.521307305083748 GO:0005006 epidermal growth factor receptor activity 1/129 50/18639 0.02 2.88976744186047 0.293696683238108 0.521307305083748 GO:0005007 fibroblast growth factor receptor activity 1/129 50/18639 0.02 2.88976744186047 0.293696683238108 0.521307305083748 GO:0005017 platelet-derived growth factor receptor activity 1/129 50/18639 0.02 2.88976744186047 0.293696683238108 0.521307305083748 GO:0005019 platelet-derived growth factor beta-receptor activity 1/129 50/18639 0.02 2.88976744186047 0.293696683238108 0.521307305083748 GO:0032813 tumor necrosis factor receptor superfamily binding 1/129 50/18639 0.02 2.88976744186047 0.293696683238108 0.521307305083748 GO:0048020 CCR chemokine receptor binding 1/129 50/18639 0.02 2.88976744186047 0.293696683238108 0.521307305083748 GO:0005010 insulin-like growth factor receptor activity 1/129 51/18639 0.0196078431372549 2.83310533515732 0.298598137208858 0.521307305083748 GO:0005021 vascular endothelial growth factor receptor activity 1/129 51/18639 0.0196078431372549 2.83310533515732 0.298598137208858 0.521307305083748 GO:0005030 neurotrophin receptor activity 1/129 51/18639 0.0196078431372549 2.83310533515732 0.298598137208858 0.521307305083748 GO:0005080 protein kinase C binding 1/129 52/18639 0.0192307692307692 2.77862254025045 0.30346583896806 0.521307305083748 GO:0004864 protein phosphatase inhibitor activity 1/129 53/18639 0.0188679245283019 2.72619569986836 0.30830001913555 0.521307305083748 GO:0005003 ephrin receptor activity 1/129 53/18639 0.0188679245283019 2.72619569986836 0.30830001913555 0.521307305083748 GO:0005005 transmembrane-ephrin receptor activity 1/129 53/18639 0.0188679245283019 2.72619569986836 0.30830001913555 0.521307305083748 GO:0017046 peptide hormone binding 1/129 53/18639 0.0188679245283019 2.72619569986836 0.30830001913555 0.521307305083748 GO:0038064 collagen receptor activity 1/129 53/18639 0.0188679245283019 2.72619569986836 0.30830001913555 0.521307305083748 GO:0015485 cholesterol binding 1/129 54/18639 0.0185185185185185 2.67571059431525 0.31310090676772 0.526235861374661 GO:0019207 kinase regulator activity 3/129 287/18639 0.0104529616724739 1.51033141560652 0.319557630918944 0.533871730696918 GO:0019212 phosphatase inhibitor activity 1/129 56/18639 0.0178571428571429 2.58014950166113 0.322603712897503 0.535752594633353 GO:0001786 phosphatidylserine binding 1/129 59/18639 0.0169491525423729 2.44895545920378 0.336613865750852 0.552442756144045 GO:0070888 E-box binding 1/129 59/18639 0.0169491525423729 2.44895545920378 0.336613865750852 0.552442756144045 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/129 60/18639 0.0166666666666667 2.40813953488372 0.341219722118889 0.556726915036083 GO:0015179 L-amino acid transmembrane transporter activity 1/129 62/18639 0.0161290322580645 2.3304576144036 0.350336455649463 0.567686509501322 GO:0004674 protein serine/threonine kinase activity 4/129 433/18639 0.0092378752886836 1.33476556206026 0.352006330264261 0.567686509501322 GO:0120013 lipid transfer activity 1/129 65/18639 0.0153846153846154 2.22289803220036 0.363777339745497 0.583298148212607 GO:1901981 phosphatidylinositol phosphate binding 2/129 185/18639 0.0108108108108108 1.56203645505971 0.367042080251373 0.584260498057934 GO:0016500 protein-hormone receptor activity 1/129 67/18639 0.0149253731343284 2.15654286706005 0.372584264680609 0.584260498057934 GO:0005216 monoatomic ion channel activity 4/129 448/18639 0.00892857142857143 1.29007475083056 0.375617421752856 0.584260498057934 GO:0005548 phospholipid transporter activity 1/129 68/18639 0.0147058823529412 2.12482900136799 0.37694225681157 0.584260498057934 GO:0030145 manganese ion binding 1/129 68/18639 0.0147058823529412 2.12482900136799 0.37694225681157 0.584260498057934 GO:0032934 sterol binding 1/129 68/18639 0.0147058823529412 2.12482900136799 0.37694225681157 0.584260498057934 GO:0019902 phosphatase binding 2/129 190/18639 0.0105263157894737 1.52093023255814 0.379420508511852 0.584852607043131 GO:0016782 transferase activity, transferring sulphur-containing groups 1/129 70/18639 0.0142857142857143 2.0641196013289 0.385568334550754 0.587833690380658 GO:0097110 scaffold protein binding 1/129 70/18639 0.0142857142857143 2.0641196013289 0.385568334550754 0.587833690380658 GO:0022804 active transmembrane transporter activity 4/129 457/18639 0.0087527352297593 1.26466846470918 0.389759540009168 0.590994085122597 GO:0042379 chemokine receptor binding 1/129 72/18639 0.0138888888888889 2.00678294573643 0.394075899464993 0.594309059193152 GO:0003684 damaged DNA binding 1/129 74/18639 0.0135135135135135 1.95254556882464 0.402466567243191 0.602533142493163 GO:0003725 double-stranded RNA binding 1/129 75/18639 0.0133333333333333 1.92651162790698 0.406618563624857 0.602533142493163 GO:0019199 transmembrane receptor protein kinase activity 1/129 78/18639 0.0128205128205128 1.85241502683363 0.418903565162188 0.602533142493163 GO:0005516 calmodulin binding 2/129 207/18639 0.00966183574879227 1.39602291877317 0.420711728934638 0.602533142493163 GO:0000049 tRNA binding 1/129 80/18639 0.0125 1.80610465116279 0.426953018571985 0.602533142493163 GO:0015101 organic cation transmembrane transporter activity 1/129 81/18639 0.0123456790123457 1.78380706287683 0.430936156704654 0.602533142493163 GO:0033192 calmodulin-dependent protein phosphatase activity 1/129 81/18639 0.0123456790123457 1.78380706287683 0.430936156704654 0.602533142493163 GO:0140791 histone H2AXS140 phosphatase activity 1/129 81/18639 0.0123456790123457 1.78380706287683 0.430936156704654 0.602533142493163 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/129 81/18639 0.0123456790123457 1.78380706287683 0.430936156704654 0.602533142493163 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/129 81/18639 0.0123456790123457 1.78380706287683 0.430936156704654 0.602533142493163 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/129 81/18639 0.0123456790123457 1.78380706287683 0.430936156704654 0.602533142493163 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/129 81/18639 0.0123456790123457 1.78380706287683 0.430936156704654 0.602533142493163 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/129 81/18639 0.0123456790123457 1.78380706287683 0.430936156704654 0.602533142493163 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/129 81/18639 0.0123456790123457 1.78380706287683 0.430936156704654 0.602533142493163 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/129 82/18639 0.0121951219512195 1.7620533182076 0.434891821958728 0.602533142493163 GO:0033549 MAP kinase phosphatase activity 1/129 82/18639 0.0121951219512195 1.7620533182076 0.434891821958728 0.602533142493163 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/129 83/18639 0.0120481927710843 1.74082376015691 0.438820202352505 0.602533142493163 GO:0030165 PDZ domain binding 1/129 83/18639 0.0120481927710843 1.74082376015691 0.438820202352505 0.602533142493163 GO:0017018 myosin phosphatase activity 1/129 84/18639 0.0119047619047619 1.72009966777409 0.442721484627593 0.602533142493163 GO:0051117 ATPase binding 1/129 84/18639 0.0119047619047619 1.72009966777409 0.442721484627593 0.602533142493163 GO:0005543 phospholipid binding 4/129 497/18639 0.00804828973843058 1.16288428243882 0.451911716976112 0.612055189496773 GO:0004197 cysteine-type endopeptidase activity 1/129 88/18639 0.0113636363636364 1.6419133192389 0.458059323168984 0.616507063431215 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/129 89/18639 0.0112359550561798 1.62346485497779 0.461827871889333 0.616507063431215 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/129 89/18639 0.0112359550561798 1.62346485497779 0.461827871889333 0.616507063431215 GO:0140793 histone H2AXY142 phosphatase activity 1/129 90/18639 0.0111111111111111 1.60542635658915 0.465570416607731 0.618543553493128 GO:0072341 modified amino acid binding 1/129 91/18639 0.010989010989011 1.58778430871454 0.469287135366564 0.620526591314082 GO:0051219 phosphoprotein binding 1/129 93/18639 0.010752688172043 1.5536384096024 0.476643801135866 0.627281228853333 GO:0042562 hormone binding 1/129 94/18639 0.0106382978723404 1.53711034141514 0.480284098216286 0.629104523015699 GO:0004725 protein tyrosine phosphatase activity 1/129 98/18639 0.0102040816326531 1.47437114380636 0.494595743424185 0.644823422501625 GO:0015171 amino acid transmembrane transporter activity 1/129 102/18639 0.00980392156862745 1.41655266757866 0.50851625397767 0.659888534231488 GO:0004722 protein serine/threonine phosphatase activity 1/129 103/18639 0.00970873786407767 1.40279972905848 0.511936516330633 0.661251333593735 GO:0019888 protein phosphatase regulator activity 1/129 107/18639 0.00934579439252336 1.35035861769181 0.525382992994691 0.675492419564603 GO:0005496 steroid binding 1/129 108/18639 0.00925925925925926 1.33785529715762 0.528686769915891 0.676622058745568 GO:0001221 transcription coregulator binding 1/129 115/18639 0.00869565217391304 1.25642062689585 0.551182923879254 0.702191944120146 GO:0019208 phosphatase regulator activity 1/129 117/18639 0.00854700854700855 1.23494335122242 0.557412394599004 0.706900264059646 GO:0032182 ubiquitin-like protein binding 1/129 120/18639 0.00833333333333333 1.20406976744186 0.566596088080335 0.715295513911373 GO:0005126 cytokine receptor binding 2/129 275/18639 0.00727272727272727 1.0508245243129 0.569966066006309 0.716308704575497 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 1/129 128/18639 0.0078125 1.12881540697674 0.590171836400884 0.738376423120389 GO:0035591 signaling adaptor activity 1/129 129/18639 0.00775193798449612 1.12006489994592 0.593027858933664 0.738637377868269 GO:0016798 hydrolase activity, acting on glycosyl bonds 1/129 130/18639 0.00769230769230769 1.11144901610018 0.595864131553737 0.738871523126634 GO:0051087 protein-folding chaperone binding 1/129 134/18639 0.00746268656716418 1.07827143353002 0.607014419396953 0.742958250824799 GO:0015297 antiporter activity 1/129 135/18639 0.00740740740740741 1.0702842377261 0.609753956813748 0.742958250824799 GO:0044325 transmembrane transporter binding 1/129 136/18639 0.00735294117647059 1.06241450068399 0.612474543690694 0.742958250824799 GO:0099094 ligand-gated monoatomic cation channel activity 1/129 136/18639 0.00735294117647059 1.06241450068399 0.612474543690694 0.742958250824799 GO:0140789 histone phosphatase activity 1/129 136/18639 0.00735294117647059 1.06241450068399 0.612474543690694 0.742958250824799 GO:0008194 UDP-glycosyltransferase activity 1/129 145/18639 0.00689655172413793 0.996471531676023 0.636128223570426 0.768051300985309 GO:0015293 symporter activity 1/129 146/18639 0.00684931506849315 0.989646384198789 0.63866631479782 0.768051300985309 GO:0022836 gated channel activity 2/129 318/18639 0.00628930817610063 0.908731899956121 0.649167376190704 0.777329175782002 GO:0030695 GTPase regulator activity 3/129 489/18639 0.00613496932515337 0.886431730632045 0.661731308716988 0.787243155943367 GO:0060589 nucleoside-triphosphatase regulator activity 3/129 490/18639 0.00612244897959184 0.884622686283816 0.663090113429001 0.787243155943367 GO:0003712 transcription coregulator activity 3/129 495/18639 0.00606060606060606 0.87568710359408 0.669825577010996 0.790924762961126 GO:0015079 potassium ion transmembrane transporter activity 1/129 160/18639 0.00625 0.903052325581395 0.67240879539667 0.790924762961126 GO:0005178 integrin binding 1/129 161/18639 0.0062111801242236 0.89744330492561 0.674695675930997 0.790924762961126 GO:0015081 sodium ion transmembrane transporter activity 1/129 164/18639 0.00609756097560976 0.8810266591038 0.681461702856337 0.795513870698402 GO:0016874 ligase activity 1/129 167/18639 0.00598802395209581 0.865199832892355 0.68808807107892 0.799902382629245 GO:0008201 heparin binding 1/129 172/18639 0.00581395348837209 0.840048674959438 0.698829408780897 0.802947403009227 GO:0003823 antigen binding 1/129 174/18639 0.00574712643678161 0.830392943063352 0.703022440168726 0.802947403009227 GO:0061630 ubiquitin protein ligase activity 2/129 353/18639 0.0056657223796034 0.818631003359905 0.704808200011925 0.802947403009227 GO:0004721 phosphoprotein phosphatase activity 1/129 175/18639 0.00571428571428571 0.825647840531561 0.705097181853981 0.802947403009227 GO:0022832 voltage-gated channel activity 1/129 175/18639 0.00571428571428571 0.825647840531561 0.705097181853981 0.802947403009227 GO:0043021 ribonucleoprotein complex binding 1/129 177/18639 0.00564971751412429 0.816318486401261 0.709203615285553 0.803379375219432 GO:0005319 lipid transporter activity 1/129 178/18639 0.00561797752808989 0.811732427488895 0.711235504226522 0.803379375219432 GO:0015276 ligand-gated monoatomic ion channel activity 1/129 186/18639 0.00537634408602151 0.7768192048012 0.726991500213593 0.804791385607836 GO:0046982 protein heterodimerization activity 2/129 369/18639 0.00542005420054201 0.783134808092267 0.727719145561883 0.804791385607836 GO:0008234 cysteine-type peptidase activity 1/129 187/18639 0.0053475935828877 0.772665091406541 0.728900029800785 0.804791385607836 GO:0022834 ligand-gated channel activity 1/129 188/18639 0.00531914893617021 0.768555170707571 0.73079532007586 0.804791385607836 GO:0046943 carboxylic acid transmembrane transporter activity 1/129 188/18639 0.00531914893617021 0.768555170707571 0.73079532007586 0.804791385607836 GO:0061659 ubiquitin-like protein ligase activity 2/129 372/18639 0.00537634408602151 0.7768192048012 0.731845092284558 0.804791385607836 GO:0005342 organic acid transmembrane transporter activity 1/129 189/18639 0.00529100529100529 0.764488741232927 0.732677462166274 0.804791385607836 GO:0016758 hexosyltransferase activity 1/129 197/18639 0.0050761421319797 0.733443513162555 0.747271996100974 0.817603478086948 GO:0051015 actin filament binding 1/129 209/18639 0.00478468899521531 0.691331923890063 0.767694149775708 0.836666671044619 GO:0000287 magnesium ion binding 1/129 230/18639 0.00434782608695652 0.628210313447927 0.799569208538487 0.868014821720769 GO:0005539 glycosaminoglycan binding 1/129 242/18639 0.00413223140495868 0.597059388814146 0.815793320904459 0.878156077324723 GO:0004842 ubiquitin-protein transferase activity 2/129 449/18639 0.0044543429844098 0.643600766561351 0.820905718889228 0.878156077324723 GO:0046873 metal ion transmembrane transporter activity 2/129 450/18639 0.00444444444444444 0.642170542635659 0.821866398566156 0.878156077324723 GO:0033218 amide binding 1/129 247/18639 0.00404858299595142 0.584973166368515 0.822162363143309 0.878156077324723 GO:0042277 peptide binding 1/129 249/18639 0.00401606425702811 0.580274586718969 0.824648359351532 0.878156077324723 GO:0003713 transcription coactivator activity 1/129 256/18639 0.00390625 0.564407703488372 0.833080867071801 0.883762592825219 GO:0003730 mRNA 3'-UTR binding 1/129 262/18639 0.00381679389312977 0.551482336232913 0.839987625773261 0.885741557452272 GO:0016757 glycosyltransferase activity 1/129 267/18639 0.00374531835205993 0.541154951659263 0.845526074505026 0.885741557452272 GO:0008514 organic anion transmembrane transporter activity 1/129 269/18639 0.00371747211895911 0.537131494769603 0.847687811408604 0.885741557452272 GO:0019787 ubiquitin-like protein transferase activity 2/129 479/18639 0.00417536534446764 0.603291741515755 0.847800294342921 0.885741557452272 GO:0016791 phosphatase activity 1/129 273/18639 0.00366300366300366 0.52926143623818 0.85192163740769 0.885741557452272 GO:1901681 sulfur compound binding 1/129 275/18639 0.00363636363636364 0.525412262156448 0.853994548224592 0.885741557452272 GO:0016755 aminoacyltransferase activity 2/129 496/18639 0.00403225806451613 0.5826144036009 0.861372896808859 0.890085326702488 GO:0015291 secondary active transmembrane transporter activity 1/129 287/18639 0.00348432055749129 0.503443805202172 0.865840995024519 0.891400876796461 GO:0001664 G protein-coupled receptor binding 1/129 297/18639 0.00336700336700337 0.486492835330045 0.874980708427819 0.897498594306476 GO:0140097 catalytic activity, acting on DNA 1/129 336/18639 0.00297619047619048 0.430024916943522 0.905090490198997 0.924982588884689 GO:0045182 translation regulator activity 1/129 356/18639 0.00280898876404494 0.405866213744447 0.91761605449351 0.934360873006166 GO:0042578 phosphoric ester hydrolase activity 1/129 363/18639 0.00275482093663912 0.398039592542764 0.921600526768381 0.935005625339557 GO:0015631 tubulin binding 1/129 385/18639 0.0025974025974026 0.375294472968892 0.932919657815447 0.943060088878658 GO:0004175 endopeptidase activity 1/129 405/18639 0.00246913580246914 0.356761412575366 0.941794710415164 0.948594672223216 GO:0016887 ATP hydrolysis activity 1/129 417/18639 0.00239808153477218 0.346494897105571 0.946549694311268 0.949954549326776 GO:0140297 DNA-binding transcription factor binding 1/129 488/18639 0.00204918032786885 0.296082729698818 0.967755234214472 0.967755234214472