category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 9/16 205/9376 25.7268292682927 MT-ND3/MT-ND2/MT-CYB/MT-CO2/MT-ATP6/MT-CO1/MT-ND4/MT-ND1/NCF1 14.7994208082568 Metabolism Energy metabolism hsa00190 Oxidative phosphorylation 8/16 138/9376 33.9710144927536 MT-ND3/MT-ND2/MT-CYB/MT-CO2/MT-ATP6/MT-CO1/MT-ND4/MT-ND1 16.132087898077 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 9/16 227/9376 23.2334801762115 MT-ND3/MT-ND2/MT-CYB/MT-CO2/MT-ATP6/MT-CO1/MT-ND4/MT-ND1/NCF1 14.0197822214148 Human Diseases Neurodegenerative disease hsa05020 Prion disease 9/16 275/9376 19.1781818181818 MT-ND3/MT-ND2/MT-CYB/MT-CO2/MT-ATP6/MT-CO1/MT-ND4/MT-ND1/NCF1 12.6496916084156 Organismal Systems Environmental adaptation hsa04714 Thermogenesis 8/16 235/9376 19.9489361702128 MT-ND3/MT-ND2/MT-CYB/MT-CO2/MT-ATP6/MT-CO1/MT-ND4/MT-ND1 12.1626893559576 Human Diseases Neurodegenerative disease hsa05012 Parkinson disease 8/16 268/9376 17.4925373134328 MT-ND3/MT-ND2/MT-CYB/MT-CO2/MT-ATP6/MT-CO1/MT-ND4/MT-ND1 11.3253352437475 Human Diseases Neurodegenerative disease hsa05016 Huntington disease 8/16 308/9376 15.2207792207792 MT-ND3/MT-ND2/MT-CYB/MT-CO2/MT-ATP6/MT-CO1/MT-ND4/MT-ND1 10.491816872853 Human Diseases Neurodegenerative disease hsa05014 Amyotrophic lateral sclerosis 8/16 368/9376 12.7391304347826 MT-ND3/MT-ND2/MT-CYB/MT-CO2/MT-ATP6/MT-CO1/MT-ND4/MT-ND1 9.49846340581092 Human Diseases Neurodegenerative disease hsa05010 Alzheimer disease 8/16 388/9376 12.0824742268041 MT-ND3/MT-ND2/MT-CYB/MT-CO2/MT-ATP6/MT-CO1/MT-ND4/MT-ND1 9.21783152159538 Human Diseases Neurodegenerative disease hsa05022 Pathways of neurodegeneration - multiple diseases 8/16 480/9376 9.76666666666667 MT-ND3/MT-ND2/MT-CYB/MT-CO2/MT-ATP6/MT-CO1/MT-ND4/MT-ND1 8.15202364168494 Organismal Systems Nervous system hsa04723 Retrograde endocannabinoid signaling 4/16 149/9376 15.7315436241611 MT-ND3/MT-ND2/MT-ND4/MT-ND1 7.4940888057687 Organismal Systems Circulatory system hsa04260 Cardiac muscle contraction 3/16 87/9376 20.2068965517241 MT-CYB/MT-CO2/MT-CO1 7.44114979600043 Human Diseases Endocrine and metabolic disease hsa04932 Non-alcoholic fatty liver disease 3/16 157/9376 11.1974522292994 MT-CYB/MT-CO2/MT-CO1 5.32730182993439 Human Diseases Cardiovascular disease hsa05416 Viral myocarditis 2/16 70/9376 16.7428571428571 CD55/HLA-B 5.46586317015063 Organismal Systems Immune system hsa04610 Complement and coagulation cascades 2/16 88/9376 13.3181818181818 CD55/PLAUR 4.79992606598296 Cellular Processes Transport and catabolism hsa04145 Phagosome 2/16 155/9376 7.56129032258065 HLA-B/NCF1 3.40544443094663 Human Diseases Immune disease hsa05330 Allograft rejection 1/16 39/9376 15.025641025641 HLA-B 3.62876670884235 Cellular Processes Transport and catabolism hsa04144 Endocytosis 2/16 250/9376 4.688 HLA-B/VPS37B 2.44359028400107 Human Diseases Endocrine and metabolic disease hsa04940 Type I diabetes mellitus 1/16 44/9376 13.3181818181818 HLA-B 3.38604938856394 Human Diseases Immune disease hsa05332 Graft-versus-host disease 1/16 45/9376 13.0222222222222 HLA-B 3.34221680582886 Human Diseases Immune disease hsa05320 Autoimmune thyroid disease 1/16 54/9376 10.8518518518519 HLA-B 3.00170430611191 Genetic Information Processing Folding, sorting and degradation hsa03018 RNA degradation 1/16 78/9376 7.51282051282051 CNOT2 2.38797263219971 Human Diseases Infectious disease: parasitic hsa05140 Leishmaniasis 1/16 78/9376 7.51282051282051 NCF1 2.38797263219971 Organismal Systems Immune system hsa04612 Antigen processing and presentation 1/16 82/9376 7.14634146341463 HLA-B 2.31115983458264 Organismal Systems Immune system hsa04666 Fc gamma R-mediated phagocytosis 1/16 98/9376 5.97959183673469 NCF1 2.04874216270521 Organismal Systems Immune system hsa04640 Hematopoietic cell lineage 1/16 100/9376 5.86 CD55 2.02005690846179 Organismal Systems Immune system hsa04670 Leukocyte transendothelial migration 1/16 116/9376 5.05172413793103 NCF1 1.81539474991399 Organismal Systems Immune system hsa04650 Natural killer cell mediated cytotoxicity 1/16 133/9376 4.40601503759398 HLA-B 1.63558684988578 Organismal Systems Development and regeneration hsa04380 Osteoclast differentiation 1/16 142/9376 4.12676056338028 NCF1 1.55221389918063 Human Diseases Cardiovascular disease hsa05418 Fluid shear stress and atherosclerosis 1/16 142/9376 4.12676056338028 NCF1 1.55221389918063 Cellular Processes Cell growth and death hsa04218 Cellular senescence 1/16 157/9376 3.73248407643312 HLA-B 1.42749062151271 Environmental Information Processing Signaling molecules and interaction hsa04514 Cell adhesion molecule (CAM) interaction 1/16 160/9376 3.6625 HLA-B 1.40438466919805 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 1/16 180/9376 3.25555555555556 HLA-B 1.26327530040782 Organismal Systems Development and regeneration hsa04360 Axon guidance 1/16 184/9376 3.18478260869565 EPHB1 1.23742771527244 Organismal Systems Immune system hsa04062 Chemokine signaling pathway 1/16 193/9376 3.03626943005181 NCF1 1.18176006231583 Organismal Systems Immune system hsa04613 Neutrophil extracellular trap formation 1/16 195/9376 3.00512820512821 NCF1 1.16982840707586 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 1/16 196/9376 2.98979591836735 HLA-B 1.16391947749262 Human Diseases Cancer: overview hsa05205 Proteoglycans in cancer 1/16 204/9376 2.87254901960784 PLAUR 1.11795406988792 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 1/16 205/9376 2.85853658536585 HLA-B 1.11236522547758 Human Diseases Cancer: overview hsa05203 Viral carcinogenesis 1/16 205/9376 2.85853658536585 HLA-B 1.11236522547758 Environmental Information Processing Signal transduction hsa04015 Rap1 signaling pathway 1/16 212/9376 2.76415094339623 SIPA1L1 1.07415965553079 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 1/16 214/9376 2.73831775700935 HLA-B 1.06352723199369 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 1/16 216/9376 2.71296296296296 NCF1 1.05301562833514 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 1/16 224/9376 2.61607142857143 HLA-B 1.01212525289738 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 1/16 227/9376 2.58149779735683 HLA-B 0.997246248759242 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 1/16 333/9376 1.75975975975976 HLA-B 0.583646444446489