category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Human Diseases Infectious disease: viral hsa05164 Influenza A 4/8 173/9376 27.0982658959538 HLA-DQA2/TRAF3/CCL5/HLA-DPB1 10.1245838792586 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 4/8 180/9376 26.0444444444444 HLA-DQA2/TRAF3/CCL5/HLA-DPB1 9.91414723187578 Human Diseases Immune disease hsa05323 Rheumatoid arthritis 3/8 95/9376 37.0105263157895 HLA-DQA2/CCL5/HLA-DPB1 10.3086329379496 Human Diseases Immune disease hsa05310 Asthma 2/8 32/9376 73.25 HLA-DQA2/HLA-DPB1 11.9633722499697 Human Diseases Immune disease hsa05330 Allograft rejection 2/8 39/9376 60.1025641025641 HLA-DQA2/HLA-DPB1 10.8079204003081 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 3/8 205/9376 17.1512195121951 HLA-DQA2/TRAF3/HLA-DPB1 6.83252287182473 Human Diseases Endocrine and metabolic disease hsa04940 Type I diabetes mellitus 2/8 44/9376 53.2727272727273 HLA-DQA2/HLA-DPB1 10.1559679900189 Human Diseases Immune disease hsa05332 Graft-versus-host disease 2/8 45/9376 52.0888888888889 HLA-DQA2/HLA-DPB1 10.0386615023933 Organismal Systems Immune system hsa04672 Intestinal immune network for IgA production 2/8 50/9376 46.88 HLA-DQA2/HLA-DPB1 9.50534526561659 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 3/8 238/9376 14.7731092436975 RPS26/TRAF3/RPL27A 6.28929671865805 Human Diseases Immune disease hsa05320 Autoimmune thyroid disease 2/8 54/9376 43.4074074074074 HLA-DQA2/HLA-DPB1 9.13253286548782 Human Diseases Immune disease hsa05321 Inflammatory bowel disease 2/8 66/9376 35.5151515151515 HLA-DQA2/HLA-DPB1 8.22269349741706 Human Diseases Cardiovascular disease hsa05416 Viral myocarditis 2/8 70/9376 33.4857142857143 HLA-DQA2/HLA-DPB1 7.97199663863404 Human Diseases Infectious disease: parasitic hsa05140 Leishmaniasis 2/8 78/9376 30.0512820512821 HLA-DQA2/HLA-DPB1 7.52878723249032 Organismal Systems Immune system hsa04612 Antigen processing and presentation 2/8 82/9376 28.5853658536585 HLA-DQA2/HLA-DPB1 7.33147792053864 Organismal Systems Immune system hsa04658 Th1 and Th2 cell differentiation 2/8 93/9376 25.2043010752688 HLA-DQA2/HLA-DPB1 6.85483548359407 Human Diseases Infectious disease: bacterial hsa05150 Staphylococcus aureus infection 2/8 99/9376 23.6767676767677 HLA-DQA2/HLA-DPB1 6.62830005859576 Organismal Systems Immune system hsa04640 Hematopoietic cell lineage 2/8 100/9376 23.44 HLA-DQA2/HLA-DPB1 6.59249293835493 Organismal Systems Immune system hsa04620 Toll-like receptor signaling pathway 2/8 109/9376 21.5045871559633 TRAF3/CCL5 6.29219086168048 Organismal Systems Immune system hsa04659 Th17 cell differentiation 2/8 109/9376 21.5045871559633 HLA-DQA2/HLA-DPB1 6.29219086168048 Human Diseases Infectious disease: parasitic hsa05145 Toxoplasmosis 2/8 112/9376 20.9285714285714 HLA-DQA2/HLA-DPB1 6.20002008503587 Environmental Information Processing Signal transduction hsa04668 TNF signaling pathway 2/8 119/9376 19.6974789915966 TRAF3/CCL5 5.99830567069454 Human Diseases Infectious disease: viral hsa05162 Measles 2/8 136/9376 17.2352941176471 TRAF3/CBLB 5.57315112645067 Human Diseases Immune disease hsa05322 Systemic lupus erythematosus 2/8 143/9376 16.3916083916084 HLA-DQA2/HLA-DPB1 5.41985660863746 Cellular Processes Transport and catabolism hsa04145 Phagosome 2/8 155/9376 15.1225806451613 HLA-DQA2/HLA-DPB1 5.18081509124132 Environmental Information Processing Signaling molecules and interaction hsa04514 Cell adhesion molecule (CAM) interaction 2/8 160/9376 14.65 HLA-DQA2/HLA-DPB1 5.08895488007666 Human Diseases Infectious disease: bacterial hsa05152 Tuberculosis 2/8 181/9376 12.9502762430939 HLA-DQA2/HLA-DPB1 4.74404233434483 Organismal Systems Immune system hsa04621 NOD-like receptor signaling pathway 2/8 187/9376 12.5347593582888 TRAF3/CCL5 4.65588673674078 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 2/8 216/9376 10.8518518518519 TRAF3/CCL5 4.28059561119504 Genetic Information Processing Translation hsa03010 Ribosome 2/8 222/9376 10.5585585585586 RPS26/RPL27A 4.21182801482991 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 2/8 224/9376 10.4642857142857 HLA-DQA2/HLA-DPB1 4.18948882862094 Human Diseases Neurodegenerative disease hsa05020 Prion disease 2/8 275/9376 8.52363636363636 MT-ND3/CCL5 3.70046905872663 Human Diseases Infectious disease: bacterial hsa05120 Epithelial cell signaling in Helicobacter pylori infection 1/8 71/9376 16.5070422535211 CCL5 3.83272047289852 Organismal Systems Immune system hsa04622 RIG-I-like receptor signaling pathway 1/8 72/9376 16.2777777777778 TRAF3 3.80275877139492 Organismal Systems Immune system hsa04623 Cytosolic DNA-sensing pathway 1/8 83/9376 14.1204819277108 CCL5 3.50847232915284 Environmental Information Processing Signal transduction hsa04012 ErbB signaling pathway 1/8 86/9376 13.6279069767442 CBLB 3.43779466512885 Human Diseases Cancer: specific types hsa05222 Small cell lung cancer 1/8 93/9376 12.6021505376344 TRAF3 3.285814076765 Organismal Systems Immune system hsa04657 IL-17 signaling pathway 1/8 94/9376 12.468085106383 TRAF3 3.26543649870275 Environmental Information Processing Signaling molecules and interaction hsa04061 Viral protein interaction with cytokine and cytokine receptor 1/8 100/9376 11.72 CCL5 3.14935491529255 Human Diseases Infectious disease: parasitic hsa05142 Chagas disease 1/8 103/9376 11.378640776699 CCL5 3.09496793285256 Environmental Information Processing Signal transduction hsa04064 NF-kappa B signaling pathway 1/8 105/9376 11.1619047619048 TRAF3 3.05994534911955 Organismal Systems Immune system hsa04625 C-type lectin receptor signaling pathway 1/8 105/9376 11.1619047619048 CBLB 3.05994534911955 Organismal Systems Immune system hsa04660 T cell receptor signaling pathway 1/8 122/9376 9.60655737704918 CBLB 2.79609438141271 Metabolism Energy metabolism hsa00190 Oxidative phosphorylation 1/8 138/9376 8.49275362318841 MT-ND3 2.59118969155309 Organismal Systems Endocrine system hsa04910 Insulin signaling pathway 1/8 138/9376 8.49275362318841 CBLB 2.59118969155309 Genetic Information Processing Folding, sorting and degradation hsa04120 Ubiquitin mediated proteolysis 1/8 142/9376 8.25352112676056 CBLB 2.54510267884295 Human Diseases Endocrine and metabolic disease hsa04936 Alcoholic liver disease 1/8 144/9376 8.13888888888889 TRAF3 2.52273226288742 Organismal Systems Nervous system hsa04723 Retrograde endocannabinoid signaling 1/8 149/9376 7.86577181208054 MT-ND3 2.46864948230511 Human Diseases Infectious disease: viral hsa05160 Hepatitis C 1/8 156/9376 7.51282051282051 TRAF3 2.39702817547807 Human Diseases Infectious disease: viral hsa05161 Hepatitis B 1/8 163/9376 7.19018404907975 TRAF3 2.32972156169015 Organismal Systems Immune system hsa04062 Chemokine signaling pathway 1/8 193/9376 6.07253886010363 CCL5 2.08074536460954 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 1/8 196/9376 5.97959183673469 TRAF3 2.05876905608674 Human Diseases Cancer: overview hsa05203 Viral carcinogenesis 1/8 205/9376 5.71707317073171 TRAF3 1.99548463215177 Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 1/8 205/9376 5.71707317073171 MT-ND3 1.99548463215177 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 1/8 227/9376 5.16299559471366 CCL5 1.85540728208206 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 1/8 227/9376 5.16299559471366 MT-ND3 1.85540728208206 Organismal Systems Environmental adaptation hsa04714 Thermogenesis 1/8 235/9376 4.98723404255319 MT-ND3 1.80890598608406 Cellular Processes Transport and catabolism hsa04144 Endocytosis 1/8 250/9376 4.688 CBLB 1.72714132332126 Human Diseases Infectious disease: bacterial hsa05131 Shigellosis 1/8 253/9376 4.63241106719368 CCL5 1.71156581605925 Human Diseases Neurodegenerative disease hsa05012 Parkinson disease 1/8 268/9376 4.37313432835821 MT-ND3 1.63718106512082 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 1/8 298/9376 3.93288590604027 CCL5 1.50354143863773 Human Diseases Neurodegenerative disease hsa05016 Huntington disease 1/8 308/9376 3.80519480519481 MT-ND3 1.46281639490694 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 1/8 333/9376 3.51951951951952 TRAF3 1.36801471637586 Human Diseases Neurodegenerative disease hsa05014 Amyotrophic lateral sclerosis 1/8 368/9376 3.18478260869565 MT-ND3 1.24946800975133 Human Diseases Neurodegenerative disease hsa05010 Alzheimer disease 1/8 388/9376 3.02061855670103 MT-ND3 1.18788899438705 Human Diseases Neurodegenerative disease hsa05022 Pathways of neurodegeneration - multiple diseases 1/8 480/9376 2.44166666666667 MT-ND3 0.947535040209385