category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Cellular Processes Cell motility hsa04820 Cytoskeleton in muscle cells 28/202 233/9376 5.57786937492032 PDLIM3/ITGA11/BGN/MYH11/SGCD/COL5A2/MYH9/ACTG2/ITGA1/COL5A1/COL1A1/LMNA/COL3A1/FHL3/FBN2/COL1A2/COL6A2/COL4A2/ITGA4/MYH10/THBS2/DAAM2/DMD/PDLIM7/FLNC/ANK2/SNTB2/SSPN 10.4997498402924 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 20/202 203/9376 4.5729893186363 ITGA11/MYLK/PDGFA/CCND1/VASP/ITGA1/COL1A1/COL1A2/ACTN4/COL6A2/PTK2/COL4A2/ITGA4/PPP1R12B/THBS2/ACTN1/PPP1R12A/FLNB/PDGFC/EMP2 7.63670465979224 NA NA hsa04518 Integrin signaling 17/202 154/9376 5.12382666838112 ITGA11/PDGFA/CCND1/ITGA1/COL1A1/COL1A2/NCK2/ACTN4/COL6A2/PTK2/COL4A2/ITGA4/THBS2/ACTN1/NPNT/FLNB/PDGFC 7.65649775195748 Organismal Systems Circulatory system hsa04270 Vascular smooth muscle contraction 15/202 134/9376 5.19580316240579 GUCY1B1/MYLK/MYH11/PRKG1/MYH9/ACTG2/GUCY1A1/ACTA2/GUCY1A2/KCNMB1/CALD1/CACNA1C/MYH10/PPP1R12B/PPP1R12A 7.25882753664314 Human Diseases Cardiovascular disease hsa05412 Arrhythmogenic right ventricular cardiomyopathy 12/202 86/9376 6.47662905825466 ITGA11/SGCD/ITGA1/LMNA/TCF7L1/SLC8A1/CDH2/CACNA1C/ITGA4/DMD/SNTB2/SSPN 7.57071068714127 Environmental Information Processing Signal transduction hsa04022 cGMP-PKG signaling pathway 16/202 166/9376 4.47381605630443 PDE3A/GUCY1B1/MYLK/PRKG1/VASP/GUCY1A1/PLN/MEF2C/GUCY1A2/KCNMB1/NFATC2/SLC8A1/CACNA1C/PPP1R12A/PDE5A/CREB3L1 6.70058934076944 Cellular Processes Cell motility hsa04810 Regulation of actin cytoskeleton 19/202 232/9376 3.80129737111642 ITGA11/MYLK/MYH11/PDGFA/MYH9/ITGA1/CYFIP2/ENAH/WASF2/ACTN4/PTK2/ITGA4/MYH10/PPP1R12B/ACTN1/PPP1R12A/ABI2/PDGFC/IQGAP1 6.41087121282072 Organismal Systems Digestive system hsa04974 Protein digestion and absorption 12/202 103/9376 5.4076708641738 COL8A1/COL5A2/COL5A1/COL1A1/COL14A1/COL3A1/COL16A1/COL1A2/SLC8A1/COL6A2/COL4A2/COL10A1 6.67420580365515 Human Diseases Cardiovascular disease hsa05414 Dilated cardiomyopathy 12/202 105/9376 5.3046676096181 ITGA11/SGCD/ITGA1/PLN/LMNA/SLC8A1/TGFB3/CACNA1C/ITGA4/DMD/SNTB2/SSPN 6.58192510967255 Human Diseases Cardiovascular disease hsa05410 Hypertrophic cardiomyopathy 11/202 99/9376 5.15731573157316 ITGA11/SGCD/ITGA1/LMNA/SLC8A1/TGFB3/CACNA1C/ITGA4/DMD/SNTB2/SSPN 6.17033555863101 NA NA hsa03273 Virion - Lassa virus and SFTS virus 5/202 17/9376 13.6517181129878 NRP2/MYH11/MYH9/PCDH7/MYH10 7.74713634065674 Human Diseases Endocrine and metabolic disease hsa04933 AGE-RAGE signaling pathway in diabetic complications 10/202 101/9376 4.59562787961965 CCND1/COL1A1/COL3A1/COL1A2/TGFB3/COL4A2/PLCG2/NOX4/CCL2/PLCE1 5.3908894007659 NA NA hsa04517 IgSF CAM signaling 18/202 299/9376 2.79426471075201 NRP2/MYLK/MYH11/MYH9/UNC5B/NCK2/ACTN4/CDH2/PTK2/TRIO/ITGA4/MYH10/ACTN1/PLCG2/EPB41L2/ANK2/IQGAP1/LMO7 4.67878293319162 Organismal Systems Immune system hsa04611 Platelet activation 11/202 126/9376 4.05217664623605 GUCY1B1/MYLK/PRKG1/VASP/GUCY1A1/COL1A1/COL3A1/GUCY1A2/COL1A2/PPP1R12A/PLCG2 5.11806769940136 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 19/202 333/9376 2.64835132161865 ITGA11/CCND1/ITGA1/COL1A1/HEYL/TCF7L1/COL1A2/NOTCH3/COL6A2/PTK2/COL4A2/ITGA4/THBS2/HLA-B/NOTCH2/DLG3/JAG1/PTGER4/CREB3L1 4.54462012156616 Environmental Information Processing Signaling molecules and interaction hsa04512 ECM-receptor interaction 9/202 89/9376 4.69373678940928 ITGA11/ITGA1/COL1A1/COL1A2/COL6A2/COL4A2/ITGA4/THBS2/NPNT 5.19523480196954 NA NA hsa04519 Cadherin signaling 21/202 404/9376 2.41270463680031 FAT1/MYO1D/VASP/CYFIP2/TCF7L1/PCDH7/ENAH/ACTN4/CDH2/PTK2/CDH6/MYO1B/DAAM2/ACTN1/EVL/LIMD1/ABI2/TAOK3/AMOTL1/KRT8/MAP2K3 4.30704466720582 Organismal Systems Endocrine system hsa04921 Oxytocin signaling pathway 11/202 154/9376 3.31541725601132 GUCY1B1/MYLK/CCND1/GUCY1A1/MEF2C/GUCY1A2/NFATC2/CACNA1C/CAMK2G/PPP1R12B/PPP1R12A 4.29891662310181 Organismal Systems Endocrine system hsa04924 Renin secretion 7/202 69/9376 4.70885349404506 PDE3A/GUCY1B1/GUCY1A1/AQP1/GUCY1A2/CACNA1C/PTGER4 4.58818923635085 Cellular Processes Cellular community - eukaryotes hsa04520 Adherens junction 8/202 93/9376 3.99276056637922 TCF7L1/ARHGAP29/WASF2/ACTN4/ACTN1/PTPRJ/IQGAP1/LMO7 4.3037915337522 Cellular Processes Cellular community - eukaryotes hsa04530 Tight junction 11/202 170/9376 3.00337798485731 MYH11/MYH9/CCND1/VASP/RUNX1/SYNPO/ACTN4/MYH10/DLG3/ACTN1/AMOTL1 3.91141437421173 Human Diseases Infectious disease: parasitic hsa05146 Amoebiasis 8/202 103/9376 3.6051139094492 COL1A1/COL3A1/COL1A2/ACTN4/TGFB3/PTK2/COL4A2/ACTN1 3.94472883965844 Environmental Information Processing Signal transduction hsa04330 Notch signaling pathway 6/202 62/9376 4.49185563717662 HEYL/NOTCH3/NOTCH2/NRARP/JAG1/ATXN1 4.0932282561544 Environmental Information Processing Signal transduction hsa04350 TGF-beta signaling pathway 8/202 110/9376 3.37569756975698 INHBA/BMP8A/GREM1/LRRC32/TGFB3/ID3/LTBP1/BMPR1A 3.71897537825392 Cellular Processes Cell motility hsa04814 Motor proteins 11/202 194/9376 2.63182606920486 MYH11/MYH9/ACTG2/MYO1D/ACTA2/KIF26B/MYO9B/MYH10/MYO1B/DYNC1I1/KIF13A 3.40790941765988 Human Diseases Cardiovascular disease hsa05416 Viral myocarditis 6/202 70/9376 3.97850070721358 SGCD/CCND1/HLA-B/DMD/SNTB2/SSPN 3.71148028944256 Human Diseases Cancer: overview hsa05205 Proteoglycans in cancer 11/202 204/9376 2.50281498738109 CCND1/COL1A1/COL1A2/PTK2/CAMK2G/PPP1R12B/PPP1R12A/PLCG2/ANK2/IQGAP1/PLCE1 3.22010870760969 Environmental Information Processing Signal transduction hsa04390 Hippo signaling pathway 9/202 157/9376 2.6607807277543 BMP8A/CCND1/TCF7L1/TGFB3/FRMD6/DLG3/LIMD1/GLI2/BMPR1A 3.1138821377426 Cellular Processes Cellular community - eukaryotes hsa04540 Gap junction 6/202 89/9376 3.12915785960619 GUCY1B1/PDGFA/PRKG1/GUCY1A1/GUCY1A2/PDGFC 2.99465707541171 Organismal Systems Immune system hsa04670 Leukocyte transendothelial migration 7/202 116/9376 2.80095595766473 VASP/THY1/ACTN4/PTK2/ITGA4/ACTN1/PLCG2 2.89606662402098 Organismal Systems Environmental adaptation hsa04713 Circadian entrainment 6/202 97/9376 2.87108298458712 GUCY1B1/PRKG1/GUCY1A1/GUCY1A2/CACNA1C/CAMK2G 2.74859203828638 Human Diseases Drug resistance: antineoplastic hsa01522 Endocrine resistance 6/202 99/9376 2.81308130813081 CCND1/NOTCH3/PTK2/NOTCH2/JAG1/CDKN2A 2.69099601487699 Cellular Processes Cell growth and death hsa04218 Cellular senescence 8/202 157/9376 2.36513842467049 CCND1/HIPK2/NFATC2/TGFB3/ETS1/HLA-B/CDKN2A/MAP2K3 2.55956736797851 Metabolism Nucleotide metabolism hsa00230 Purine metabolism 7/202 128/9376 2.53836633663366 PDE3A/GUCY1B1/GUCY1A1/PDE4D/GUCY1A2/PAPSS2/PDE5A 2.60029605547314 Metabolism Glycan biosynthesis and metabolism hsa00514 Other types of O-glycan biosynthesis 4/202 49/9376 3.78904829258436 GALNT16/ST6GAL2/XXYLT1/GALNT5 2.90445759941491 Human Diseases Cancer: specific types hsa05214 Glioma 5/202 76/9376 3.05367378843147 PDGFA/CCND1/CAMK2G/CDKN2A/PLCG2 2.66734220632368 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 14/202 362/9376 1.79508779607242 ITGA11/PDGFA/CCND1/ITGA1/COL1A1/COL1A2/COL6A2/PTK2/COL4A2/ITGA4/THBS2/BDNF/PDGFC/CREB3L1 2.2892464578671 Human Diseases Cancer: specific types hsa05215 Prostate cancer 6/202 106/9376 2.62731178778255 PDGFA/CCND1/TCF7L1/ERG/PDGFC/CREB3L1 2.50014841907744 Human Diseases Infectious disease: bacterial hsa05130 Pathogenic Escherichia coli infection 9/202 200/9376 2.08871287128713 MYH11/MYH9/MYO1D/CYFIP2/WASF2/NCK2/MYH10/MYO1B/CYTH3 2.30931729339368 Environmental Information Processing Signal transduction hsa04371 Apelin signaling pathway 7/202 140/9376 2.32079207920792 MYLK/CCND1/MEF2C/ACTA2/NOTCH3/SLC8A1/JAG1 2.33635302963854 Environmental Information Processing Signal transduction hsa04015 Rap1 signaling pathway 9/202 212/9376 1.97048384083691 PDGFA/VASP/ENAH/PRKD1/RAPGEF5/EVL/PDGFC/MAP2K3/PLCE1 2.12078016899652 Organismal Systems Nervous system hsa04730 Long-term depression 4/202 60/9376 3.09438943894389 GUCY1B1/PRKG1/GUCY1A1/GUCY1A2 2.41490627249428 Organismal Systems Development and regeneration hsa04360 Axon guidance 8/202 184/9376 2.01808006887645 UNC5B/ENAH/NFATC2/NCK2/SEMA5A/PTK2/CAMK2G/PLCG2 2.06951126127805 Metabolism Amino acid metabolism hsa00310 Lysine degradation 4/202 63/9376 2.94703756089895 SMYD3/PLOD2/ASH1L/KMT2E 2.30081530684685 Environmental Information Processing Signal transduction hsa04020 Calcium signaling pathway 10/202 254/9376 1.82739533795899 MYLK/PDGFA/PLN/NFATC2/SLC8A1/CACNA1C/CAMK2G/PDGFC/PLCG2/PLCE1 1.98365823190018 Organismal Systems Endocrine system hsa04919 Thyroid hormone signaling pathway 6/202 122/9376 2.28274630741763 CCND1/PLN/NOTCH3/NOTCH2/PLCG2/PLCE1 2.11610832582521 Human Diseases Endocrine and metabolic disease hsa04934 Cushing syndrome 7/202 155/9376 2.09619929734909 CCND1/TCF7L1/AHR/CACNA1C/CAMK2G/CDKN2A/CREB3L1 2.0419650874704 Metabolism Lipid metabolism hsa00561 Glycerolipid metabolism 4/202 65/9376 2.85635948210206 LCLAT1/PLPP4/DGKH/DGKD 2.22844823750911 Environmental Information Processing Signal transduction hsa04024 cAMP signaling pathway 9/202 226/9376 1.8484184701656 PDE3A/PLN/PDE4D/CACNA1C/CAMK2G/PPP1R12A/BDNF/CREB3L1/PLCE1 1.91573636035351 Organismal Systems Immune system hsa04666 Fc gamma R-mediated phagocytosis 5/202 98/9376 2.36815518286523 VASP/ASAP1/ASAP2/WASF2/PLCG2 2.02024094449842 Organismal Systems Endocrine system hsa04926 Relaxin signaling pathway 6/202 130/9376 2.14226961157654 COL1A1/ACTA2/COL3A1/COL1A2/COL4A2/CREB3L1 1.94601108502307 Organismal Systems Sensory system hsa04750 Inflammatory mediator regulation of TRP channels 5/202 99/9376 2.34423442344234 TRPV2/CAMK2G/PLCG2/PTGER4/MAP2K3 1.99512810612619 Human Diseases Cancer: overview hsa05231 Choline metabolism in cancer 5/202 99/9376 2.34423442344234 PDGFA/WASF2/DGKH/DGKD/PDGFC 1.99512810612619 Organismal Systems Excretory system hsa04962 Vasopressin-regulated water reabsorption 3/202 44/9376 3.16471647164716 ARHGDIB/DYNC1I1/CREB3L1 2.13561002065627 Environmental Information Processing Signal transduction hsa04014 Ras signaling pathway 9/202 238/9376 1.75522090024128 PDGFA/ETS1/NF1/RAPGEF5/RALBP1/BDNF/PDGFC/PLCG2/PLCE1 1.75113188956126 Human Diseases Cancer: specific types hsa05218 Melanoma 4/202 73/9376 2.54333378543334 PDGFA/CCND1/CDKN2A/PDGFC 1.96422727871831 Metabolism Glycan biosynthesis and metabolism hsa00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate 2/202 21/9376 4.42055634134842 CHST11/CSGALNACT1 2.32844752403038 Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 8/202 205/9376 1.81134991547935 COL1A1/PLN/MT-ND3/COL3A1/COL1A2/TGFB3/CAMK2G/NDUFA4L2 1.74284487663292 Human Diseases Infectious disease: bacterial hsa05135 Yersinia infection 6/202 138/9376 2.01808006887645 NFATC2/WASF2/PTK2/ITGA4/MAP2K3/CCL2 1.78778156449576 Human Diseases Cancer: specific types hsa05212 Pancreatic cancer 4/202 77/9376 2.41121254982641 CCND1/TGFB3/RALBP1/CDKN2A 1.84502231722736 Human Diseases Cancer: specific types hsa05220 Chronic myeloid leukemia 4/202 77/9376 2.41121254982641 CCND1/RUNX1/TGFB3/CDKN2A 1.84502231722736 Environmental Information Processing Signal transduction hsa04310 Wnt signaling pathway 7/202 178/9376 1.82534208477027 CCND1/TCF7L1/NFATC2/APCDD1L/CAMK2G/DAAM2/FRZB 1.64960226485786 Human Diseases Infectious disease: parasitic hsa05144 Malaria 3/202 50/9376 2.7849504950495 TGFB3/THBS2/CCL2 1.87778310496516 Human Diseases Drug resistance: antineoplastic hsa01521 EGFR tyrosine kinase inhibitor resistance 4/202 80/9376 2.32079207920792 PDGFA/NF1/PDGFC/PLCG2 1.76040805387995 Human Diseases Cancer: specific types hsa05224 Breast cancer 6/202 148/9376 1.88172330746588 CCND1/HEYL/TCF7L1/NOTCH3/NOTCH2/JAG1 1.60432126810995 Environmental Information Processing Signal transduction hsa04072 Phospholipase D signaling pathway 6/202 149/9376 1.86909429197953 PDGFA/DGKH/CYTH3/DGKD/PDGFC/PLCG2 1.58676176297487 Environmental Information Processing Signal transduction hsa04668 TNF signaling pathway 5/202 119/9376 1.95024544471254 JAG1/DAB2IP/CREB3L1/MAP2K3/CCL2 1.54794704768608 Environmental Information Processing Signal transduction hsa04012 ErbB signaling pathway 4/202 86/9376 2.15887635275155 NCK2/PTK2/CAMK2G/PLCG2 1.60199230138247 Organismal Systems Endocrine system hsa04911 Insulin secretion 4/202 86/9376 2.15887635275155 KCNMB1/CACNA1C/CAMK2G/CREB3L1 1.60199230138247 Organismal Systems Nervous system hsa04722 Neurotrophin signaling pathway 5/202 120/9376 1.93399339933993 ARHGDIB/SORT1/CAMK2G/BDNF/PLCG2 1.52793441183222 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 8/202 227/9376 1.63580058446373 CCND1/NFATC2/PTK2/HLA-B/CDKN2A/PTGER4/CREB3L1/CCL2 1.43889463277833 Organismal Systems Endocrine system hsa04935 Growth hormone synthesis, secretion and action 5/202 122/9376 1.90228858951469 PTK2/CACNA1C/PLCG2/CREB3L1/MAP2K3 1.48847857563739 Environmental Information Processing Signal transduction hsa04392 Hippo signaling pathway - multiple species 2/202 29/9376 3.20109252304541 FRMD6/LIMD1 1.7615019616551 Environmental Information Processing Signal transduction hsa04370 VEGF signaling pathway 3/202 60/9376 2.32079207920792 NFATC2/PTK2/PLCG2 1.5229207221119 Organismal Systems Immune system hsa04658 Th1 and Th2 cell differentiation 4/202 93/9376 1.99638028318961 NFATC2/NOTCH3/NOTCH2/JAG1 1.43286204561868 Organismal Systems Digestive system hsa04970 Salivary secretion 4/202 93/9376 1.99638028318961 GUCY1B1/PRKG1/GUCY1A1/GUCY1A2 1.43286204561868 Human Diseases Cancer: overview hsa05202 Transcriptional misregulation in cancer 7/202 201/9376 1.61647209497069 PDGFA/MEF2C/RUNX1/ERG/ETV6/PTK2/ETV1 1.31096280522039 Cellular Processes Cell growth and death hsa04215 Apoptosis - multiple species 2/202 32/9376 2.9009900990099 SEPTIN4/BIRC6 1.59834447523626 Environmental Information Processing Signal transduction hsa04070 Phosphatidylinositol signaling system 4/202 98/9376 1.89452414629218 DGKH/DGKD/PLCG2/PLCE1 1.32086939319074 Organismal Systems Endocrine system hsa04925 Aldosterone synthesis and secretion 4/202 98/9376 1.89452414629218 PRKD1/CACNA1C/CAMK2G/CREB3L1 1.32086939319074 Human Diseases Infectious disease: bacterial hsa05131 Shigellosis 8/202 253/9376 1.46769459554651 WASF2/ACTN4/PTK2/ACTN1/CYTH3/PLCG2/SEPTIN9/PLCE1 1.11901454004553 Human Diseases Cancer: specific types hsa05221 Acute myeloid leukemia 3/202 68/9376 2.04775771694817 CCND1/TCF7L1/RUNX1 1.28667568000763 Metabolism Glycan biosynthesis and metabolism hsa00512 Mucin type O-glycan biosynthesis 2/202 36/9376 2.57865786578658 GALNT16/GALNT5 1.4081463219477 Human Diseases Substance dependence hsa05031 Amphetamine addiction 3/202 69/9376 2.01808006887645 CACNA1C/CAMK2G/CREB3L1 1.25945767910819 Metabolism Lipid metabolism hsa00564 Glycerophospholipid metabolism 4/202 104/9376 1.78522467631379 LCLAT1/PLPP4/DGKH/DGKD 1.19482926812741 Human Diseases Cancer: specific types hsa05216 Thyroid cancer 2/202 37/9376 2.50896440995451 CCND1/TCF7L1 1.3646196670723 Human Diseases Cardiovascular disease hsa05418 Fluid shear stress and atherosclerosis 5/202 142/9376 1.63436061916051 PDGFA/MEF2C/PTK2/BMPR1A/CCL2 1.13023149830181 Metabolism Energy metabolism hsa00920 Sulfur metabolism 1/202 10/9376 4.64158415841584 PAPSS2 1.70960283532743 Environmental Information Processing Signal transduction hsa04010 MAPK signaling pathway 9/202 300/9376 1.39247524752475 PDGFA/MEF2C/TGFB3/CACNA1C/NF1/BDNF/TAOK3/PDGFC/MAP2K3 1.02519767078139 Metabolism Metabolism of cofactors and vitamins hsa00670 One carbon pool by folate 2/202 39/9376 2.38029956841838 TYMS/ALDH1L2 1.28169276070403 Human Diseases Cancer: specific types hsa05223 Non-small cell lung cancer 3/202 73/9376 1.907500339075 CCND1/CDKN2A/PLCG2 1.15499118744215 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 7/202 224/9376 1.45049504950495 CCND1/NFATC2/TGFB3/ETS1/HLA-B/CDKN2A/CREB3L1 1.01260013591225 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 7/202 227/9376 1.43132551140577 MT-ND3/PRKD1/AHR/PTK2/NDUFA4L2/NOX4/PTPRJ 0.976142486351436 Cellular Processes Cell growth and death hsa04115 p53 signaling pathway 3/202 75/9376 1.85663366336634 CCND1/ZMAT3/CDKN2A 1.10520515396273 Human Diseases Cancer: specific types hsa05219 Bladder cancer 2/202 41/9376 2.26418739434919 CCND1/CDKN2A 1.20372748711763 Metabolism Carbohydrate metabolism hsa00562 Inositol phosphate metabolism 3/202 78/9376 1.78522467631379 PLCG2/ISYNA1/PLCE1 1.03330474723586 Human Diseases Infectious disease: bacterial hsa05100 Bacterial invasion of epithelial cells 3/202 78/9376 1.78522467631379 WASF2/PTK2/SEPTIN9 1.03330474723586 Organismal Systems Circulatory system hsa04261 Adrenergic signaling in cardiomyocytes 5/202 154/9376 1.50700784364151 PLN/SLC8A1/CACNA1C/CAMK2G/CREB3L1 0.941335494246152 Cellular Processes Transport and catabolism hsa04148 Efferocytosis 5/202 157/9376 1.47821151541906 ANO4/NFATC2/PTK2/CAMK2G/PTGER4 0.89662305868624 Environmental Information Processing Signaling molecules and interaction hsa04514 Cell adhesion molecule (CAM) interaction 5/202 160/9376 1.45049504950495 CDH2/ITGA4/HLA-B/ALCAM/CD276 0.852826597009532 Human Diseases Cancer: overview hsa05203 Viral carcinogenesis 6/202 205/9376 1.35851243660951 CCND1/ACTN4/HLA-B/ACTN1/CDKN2A/CREB3L1 0.770113549571176 Human Diseases Substance dependence hsa05030 Cocaine addiction 2/202 49/9376 1.89452414629218 BDNF/CREB3L1 0.931539070680997 Human Diseases Cancer: specific types hsa05210 Colorectal cancer 3/202 87/9376 1.6005462615227 CCND1/TCF7L1/TGFB3 0.835032863087028 Metabolism Glycan biosynthesis and metabolism hsa00603 Glycosphingolipid biosynthesis - globo and isoglobo series 1/202 16/9376 2.9009900990099 A4GALT 1.12923382085357 Human Diseases Infectious disease: bacterial hsa05110 Vibrio cholerae infection 2/202 51/9376 1.8202290817317 KDELR3/PLCG2 0.871520859510849 Human Diseases Cancer: specific types hsa05225 Hepatocellular carcinoma 5/202 170/9376 1.36517181129878 CCND1/TCF7L1/TGFB3/CDKN2A/PLCG2 0.712964943494027 Metabolism Metabolism of other amino acids hsa00450 Selenocompound metabolism 1/202 17/9376 2.73034362259755 PAPSS2 1.05955632592603 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 8/202 298/9376 1.24606286131969 INHBA/CCL11/BMP8A/TGFB3/IL34/TNFSF15/BMPR1A/CCL2 0.640532348666068 Organismal Systems Endocrine system hsa04912 GnRH signaling pathway 3/202 93/9376 1.49728521239221 CACNA1C/CAMK2G/MAP2K3 0.715129673585306 Human Diseases Cancer: specific types hsa05222 Small cell lung cancer 3/202 93/9376 1.49728521239221 CCND1/PTK2/COL4A2 0.715129673585306 Human Diseases Cancer: overview hsa05207 Chemical carcinogenesis - receptor activation 6/202 217/9376 1.28338732490761 CCND1/AHR/CACNA1C/NOTCH2/JAG1/CREB3L1 0.626712293805682 Metabolism Glycan biosynthesis and metabolism hsa00510 N-Glycan biosynthesis 2/202 56/9376 1.65770862800566 TUSC3/ST6GAL2 0.732489749357438 Environmental Information Processing Signal transduction hsa04340 Hedgehog signaling pathway 2/202 56/9376 1.65770862800566 CCND1/GLI2 0.732489749357438 Human Diseases Cancer: specific types hsa05213 Endometrial cancer 2/202 59/9376 1.57341835878503 CCND1/TCF7L1 0.655603866903955 Environmental Information Processing Signaling molecules and interaction hsa04061 Viral protein interaction with cytokine and cytokine receptor 3/202 100/9376 1.39247524752475 CCL11/IL34/CCL2 0.585482417062333 Organismal Systems Immune system hsa04640 Hematopoietic cell lineage 3/202 100/9376 1.39247524752475 ITGA1/ITGA4/CD9 0.585482417062333 Organismal Systems Endocrine system hsa04916 Melanogenesis 3/202 101/9376 1.37868836388589 TCF7L1/CAMK2G/CREB3L1 0.567763727341494 Human Diseases Endocrine and metabolic disease hsa04936 Alcoholic liver disease 4/202 144/9376 1.28932893289329 CCND1/TCF7L1/NOX4/MAP2K3 0.519167106372119 Organismal Systems Digestive system hsa04978 Mineral absorption 2/202 61/9376 1.52183087161175 MT1E/SLC8A1 0.606715669322628 Organismal Systems Excretory system hsa04964 Proximal tubule bicarbonate reclamation 1/202 23/9376 2.01808006887645 AQP1 0.725357892896534 Human Diseases Cancer: overview hsa05206 MicroRNAs in cancer 8/202 323/9376 1.1496183674095 PDGFA/CCND1/NOTCH3/NOTCH2/FSCN1/CDKN2A/PLCG2/ZEB2 0.406042850128238 Organismal Systems Immune system hsa04625 C-type lectin receptor signaling pathway 3/202 105/9376 1.32616690240453 NFATC2/PLK3/PLCG2 0.49871588693254 Human Diseases Cancer: specific types hsa05217 Basal cell carcinoma 2/202 63/9376 1.47351878044947 TCF7L1/GLI2 0.559557391196186 Organismal Systems Environmental adaptation hsa04714 Thermogenesis 6/202 235/9376 1.18508531704234 BMP8A/PRKG1/MT-ND3/NDUFA4L2/CREB3L1/MAP2K3 0.426374279861849 Metabolism Glycan biosynthesis and metabolism hsa00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 1/202 24/9376 1.93399339933993 EXT1 0.679796828056086 Organismal Systems Endocrine system hsa04927 Cortisol synthesis and secretion 2/202 65/9376 1.42817974105103 CACNA1C/CREB3L1 0.514004102374507 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 5/202 196/9376 1.18407759143261 CCND1/TCF7L1/NFATC2/HLA-B/PLCG2 0.386446673486211 Organismal Systems Immune system hsa04659 Th17 cell differentiation 3/202 109/9376 1.27750022708693 RUNX1/NFATC2/AHR 0.432403265763038 Organismal Systems Nervous system hsa04720 Long-term potentiation 2/202 67/9376 1.38554750997488 CACNA1C/CAMK2G 0.469943604728431 Organismal Systems Immune system hsa04664 Fc epsilon RI signaling pathway 2/202 69/9376 1.3453867125843 PLCG2/MAP2K3 0.42727478979752 Metabolism Lipid metabolism hsa01040 Biosynthesis of unsaturated fatty acids 1/202 27/9376 1.71910524385772 ELOVL2 0.555231008973667 Human Diseases Cancer: specific types hsa05211 Renal cell carcinoma 2/202 70/9376 1.32616690240453 TGFB3/ETS1 0.406433352999076 Organismal Systems Nervous system hsa04725 Cholinergic synapse 3/202 115/9376 1.21084804132587 CACNA1C/CAMK2G/CREB3L1 0.337575954332804 Organismal Systems Endocrine system hsa04928 Parathyroid hormone synthesis, secretion and action 3/202 115/9376 1.21084804132587 MEF2C/PDE4D/CREB3L1 0.337575954332804 Cellular Processes Transport and catabolism hsa04144 Endocytosis 6/202 250/9376 1.1139801980198 ASAP1/ASAP2/HLA-B/CYTH3/SNX6/EHD3 0.271044834039082 Metabolism Lipid metabolism hsa00062 Fatty acid elongation 1/202 28/9376 1.65770862800566 ELOVL2 0.517172183443339 Metabolism Glycan biosynthesis and metabolism hsa00601 Glycosphingolipid biosynthesis - lacto and neolacto series 1/202 28/9376 1.65770862800566 A4GALT 0.517172183443339 Organismal Systems Excretory system hsa04966 Collecting duct acid secretion 1/202 28/9376 1.65770862800566 SLC12A7 0.517172183443339 Human Diseases Infectious disease: viral hsa05161 Hepatitis B 4/202 163/9376 1.13903905727996 NFATC2/TGFB3/CREB3L1/MAP2K3 0.265712530949583 Metabolism Carbohydrate metabolism hsa00020 Citrate cycle (TCA cycle) 1/202 30/9376 1.54719471947195 IDH2 0.445421926286873 Human Diseases Drug resistance: antineoplastic hsa01523 Antifolate resistance 1/202 30/9376 1.54719471947195 TYMS 0.445421926286873 Organismal Systems Digestive system hsa04971 Gastric acid secretion 2/202 76/9376 1.22146951537259 MYLK/CAMK2G 0.287647916185629 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 5/202 214/9376 1.0844822800037 NFATC2/PTK2/HLA-B/PLCG2/MAP2K3 0.185506582223551 NA NA hsa04981 Folate transport and metabolism 1/202 31/9376 1.49728521239221 TYMS 0.41150838983464 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 5/202 216/9376 1.07444077741107 NFATC2/PTK2/CAMK2G/MAP2K3/CCL2 0.164237374483138 Human Diseases Immune disease hsa05310 Asthma 1/202 32/9376 1.45049504950495 CCL11 0.378774341787759 Human Diseases Infectious disease: parasitic hsa05140 Leishmaniasis 2/202 78/9376 1.19014978420919 TGFB3/ITGA4 0.250224783601572 Metabolism Global and overview maps hsa01210 2-Oxocarboxylic acid metabolism 1/202 33/9376 1.40654065406541 IDH2 0.34713606174458 Environmental Information Processing Signal transduction hsa04068 FoxO signaling pathway 3/202 133/9376 1.04697387031936 CCND1/TGFB3/PLK3 0.0809576034527766 Organismal Systems Immune system hsa04650 Natural killer cell mediated cytotoxicity 3/202 133/9376 1.04697387031936 NFATC2/HLA-B/PLCG2 0.0809576034527766 Organismal Systems Nervous system hsa04728 Dopaminergic synapse 3/202 133/9376 1.04697387031936 CACNA1C/CAMK2G/CREB3L1 0.0809576034527766 Organismal Systems Circulatory system hsa04260 Cardiac muscle contraction 2/202 87/9376 1.06703084101514 SLC8A1/CACNA1C 0.0932034027588136 Cellular Processes Cell growth and death hsa04210 Apoptosis 3/202 137/9376 1.01640529016405 LMNA/SEPTIN4/DAB2IP 0.0287020998735316 Human Diseases Immune disease hsa05330 Allograft rejection 1/202 39/9376 1.19014978420919 HLA-B 0.176565730691064 Human Diseases Cancer: overview hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer 2/202 90/9376 1.03146314631463 NFATC2/MAP2K3 0.0445031774523645 Organismal Systems Immune system hsa04662 B cell receptor signaling pathway 2/202 91/9376 1.02012838646502 NFATC2/PLCG2 0.0286299546071337 Human Diseases Substance dependence hsa05032 Morphine addiction 2/202 91/9376 1.02012838646502 PDE3A/PDE4D 0.0286299546071337 Genetic Information Processing Folding, sorting and degradation hsa04120 Ubiquitin mediated proteolysis 3/202 142/9376 0.980616371496305 BIRC6/UBE2E2/RHOBTB1 -0.0345355414957028 Organismal Systems Immune system hsa04062 Chemokine signaling pathway 4/202 193/9376 0.961986354075822 CCL11/PTK2/PLCG2/CCL2 -0.0791786043888757 Cellular Processes Cellular community - eukaryotes hsa04550 Signaling pathways regulating pluripotency of stem cells 3/202 144/9376 0.966996699669967 INHBA/ID3/BMPR1A -0.0592205824759073 Organismal Systems Immune system hsa04657 IL-17 signaling pathway 2/202 94/9376 0.987571097535285 CCL11/CCL2 -0.0179704056111416 Human Diseases Immune disease hsa05323 Rheumatoid arthritis 2/202 95/9376 0.977175612298072 TGFB3/CCL2 -0.0331776412724677 Metabolism Glycan biosynthesis and metabolism hsa00513 Various types of N-glycan biosynthesis 1/202 44/9376 1.05490549054905 TUSC3 0.0541672396091611 Genetic Information Processing Transcription hsa03022 Basal transcription factors 1/202 44/9376 1.05490549054905 ERCC2 0.0541672396091611 Human Diseases Endocrine and metabolic disease hsa04940 Type I diabetes mellitus 1/202 44/9376 1.05490549054905 HLA-B 0.0541672396091611 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 5/202 248/9376 0.935803257745129 CYFIP2/TCF7L1/DYNC1I1/CYTH3/MAP2K3 -0.152031286145025 Human Diseases Immune disease hsa05332 Graft-versus-host disease 1/202 45/9376 1.03146314631463 HLA-B 0.0313925263244739 Organismal Systems Nervous system hsa04723 Retrograde endocannabinoid signaling 3/202 149/9376 0.934547145989767 MT-ND3/CACNA1C/NDUFA4L2 -0.119501516670253 Human Diseases Cancer: specific types hsa05226 Gastric cancer 3/202 150/9376 0.928316831683168 CCND1/TCF7L1/TGFB3 -0.131322170400792 Human Diseases Endocrine and metabolic disease hsa04930 Type II diabetes mellitus 1/202 47/9376 0.987571097535285 CACNA1C -0.0126749459890906 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 4/202 205/9376 0.905674957739676 CCND1/HLA-B/PLCG2/MAP2K3 -0.202617777490571 NA NA hsa03272 Virion - Hepatitis viruses 1/202 48/9376 0.966996699669967 CD9 -0.0340146241489103 Cellular Processes Transport and catabolism hsa04145 Phagosome 3/202 155/9376 0.898371127435324 THBS2/HLA-B/DYNC1I1 -0.189311022327685 Human Diseases Infectious disease: parasitic hsa05142 Chagas disease 2/202 103/9376 0.901278477362299 TGFB3/CCL2 -0.149486606336637 Organismal Systems Immune system hsa04672 Intestinal immune network for IgA production 1/202 50/9376 0.928316831683168 ITGA4 -0.0754113028619244 Cellular Processes Cell growth and death hsa04110 Cell cycle 3/202 158/9376 0.881313447800476 CCND1/TGFB3/CDKN2A -0.223251127307725 Organismal Systems Endocrine system hsa04922 Glucagon signaling pathway 2/202 107/9376 0.867585824002961 CAMK2G/CREB3L1 -0.204405174193998 Organismal Systems Digestive system hsa04979 Cholesterol metabolism 1/202 52/9376 0.892612338156893 SORT1 -0.115222390437392 Human Diseases Endocrine and metabolic disease hsa04931 Insulin resistance 2/202 109/9376 0.851666818057953 MLXIP/CREB3L1 -0.231134053352223 Organismal Systems Excretory system hsa04961 Endocrine and other factor-regulated calcium reabsorption 1/202 53/9376 0.875770595927517 SLC8A1 -0.134575638689978 Environmental Information Processing Signal transduction hsa04066 HIF-1 signaling pathway 2/202 110/9376 0.843924392439244 CAMK2G/PLCG2 -0.244324592933709 Human Diseases Immune disease hsa05320 Autoimmune thyroid disease 1/202 54/9376 0.85955262192886 HLA-B -0.153581152280037 Human Diseases Infectious disease: parasitic hsa05145 Toxoplasmosis 2/202 112/9376 0.828854314002829 TGFB3/MAP2K3 -0.270369469993293 Metabolism Global and overview maps hsa01212 Fatty acid metabolism 1/202 57/9376 0.814313010248393 ELOVL2 -0.208648949629251 Human Diseases Neurodegenerative disease hsa05022 Pathways of neurodegeneration - multiple diseases 9/202 480/9376 0.87029702970297 HIP1/MT-ND3/CACNA1C/CAMK2G/NDUFA4L2/BDNF/NOX4/ATXN1/MAP2K3 -0.432867628146345 Metabolism Nucleotide metabolism hsa00240 Pyrimidine metabolism 1/202 59/9376 0.786709179392516 TYMS -0.243860847186107 Metabolism Metabolism of other amino acids hsa00480 Glutathione metabolism 1/202 59/9376 0.786709179392516 IDH2 -0.243860847186107 Organismal Systems Endocrine system hsa04923 Regulation of lipolysis in adipocytes 1/202 59/9376 0.786709179392516 PRKG1 -0.243860847186107 Environmental Information Processing Signal transduction hsa04152 AMPK signaling pathway 2/202 122/9376 0.760915435805876 CCND1/CREB3L1 -0.394410674926044 Organismal Systems Immune system hsa04660 T cell receptor signaling pathway 2/202 122/9376 0.760915435805876 NFATC2/NCK2 -0.394410674926044 Genetic Information Processing Replication and repair hsa03420 Nucleotide excision repair 1/202 63/9376 0.736759390224737 ERCC2 -0.311071566629144 Human Diseases Infectious disease: bacterial hsa05152 Tuberculosis 3/202 181/9376 0.769323341173896 TGFB3/CAMK2G/PLK3 -0.464995797669517 Organismal Systems Endocrine system hsa04929 GnRH secretion 1/202 65/9376 0.714089870525514 CACNA1C -0.343217965192796 Human Diseases Immune disease hsa05321 Inflammatory bowel disease 1/202 66/9376 0.703270327032703 TGFB3 -0.358955043890864 Organismal Systems Immune system hsa04621 NOD-like receptor signaling pathway 3/202 187/9376 0.744639169799333 TRPV2/GBP2/CCL2 -0.523386979266643 Organismal Systems Endocrine system hsa04917 Prolactin signaling pathway 1/202 71/9376 0.653744247664203 CCND1 -0.434560189555671 Human Diseases Infectious disease: bacterial hsa05120 Epithelial cell signaling in Helicobacter pylori infection 1/202 71/9376 0.653744247664203 PLCG2 -0.434560189555671 Human Diseases Cancer: overview hsa05230 Central carbon metabolism in cancer 1/202 71/9376 0.653744247664203 IDH2 -0.434560189555671 Genetic Information Processing Information processing in viruses hsa03250 Viral life cycle - HIV-1 1/202 73/9376 0.635833446358334 SERINC5 -0.463480995110174 Human Diseases Neurodegenerative disease hsa05016 Huntington disease 5/202 308/9376 0.753503921820753 HIP1/MT-ND3/NDUFA4L2/BDNF/CREB3L1 -0.652696932255916 Metabolism Energy metabolism hsa00190 Oxidative phosphorylation 2/202 138/9376 0.672693356292151 MT-ND3/NDUFA4L2 -0.574761063934437 Cellular Processes Cell growth and death hsa04114 Oocyte meiosis 2/202 138/9376 0.672693356292151 CAMK2G/CPEB3 -0.574761063934437 Metabolism Global and overview maps hsa01230 Biosynthesis of amino acids 1/202 75/9376 0.618877887788779 IDH2 -0.491713250037049 Human Diseases Drug resistance: antineoplastic hsa01524 Platinum drug resistance 1/202 75/9376 0.618877887788779 CDKN2A -0.491713250037049 Organismal Systems Endocrine system hsa04918 Thyroid hormone synthesis 1/202 75/9376 0.618877887788779 CREB3L1 -0.491713250037049 Organismal Systems Development and regeneration hsa04380 Osteoclast differentiation 2/202 142/9376 0.653744247664203 NFATC2/PLCG2 -0.61691906139446 Human Diseases Immune disease hsa05322 Systemic lupus erythematosus 2/202 143/9376 0.649172609568649 ACTN4/ACTN1 -0.627295322265913 Organismal Systems Immune system hsa04612 Antigen processing and presentation 1/202 82/9376 0.566046848587298 HLA-B -0.585639543930604 Genetic Information Processing Chromosome hsa03083 Polycomb repressive complex 1/202 83/9376 0.559227007038053 AEBP2 -0.598491530919557 Cellular Processes Transport and catabolism hsa04146 Peroxisome 1/202 83/9376 0.559227007038053 IDH2 -0.598491530919557 Metabolism Global and overview maps hsa01232 Nucleotide metabolism 1/202 85/9376 0.546068724519511 TYMS -0.623807072236239 Organismal Systems Sensory system hsa04742 Taste transduction 1/202 86/9376 0.539719088187888 CACNA1C -0.636277093277082 Human Diseases Neurodegenerative disease hsa05020 Prion disease 4/202 275/9376 0.675139513951395 MT-ND3/CACNA1C/NDUFA4L2/CREB3L1 -0.811335790602364 NA NA hsa04382 Cornified envelope formation 3/202 217/9376 0.641693662453803 COL4A2/KRT8/DST -0.792396014048627 Human Diseases Endocrine and metabolic disease hsa04932 Non-alcoholic fatty liver disease 2/202 157/9376 0.591284606167623 MLXIP/NDUFA4L2 -0.76632125060603 Organismal Systems Nervous system hsa04727 GABAergic synapse 1/202 89/9376 0.521526309934364 CACNA1C -0.672972468851338 Organismal Systems Aging hsa04211 Longevity regulating pathway 1/202 90/9376 0.515731573157316 CREB3L1 -0.684975479529051 Organismal Systems Digestive system hsa04976 Bile secretion 1/202 90/9376 0.515731573157316 AQP1 -0.684975479529051 Environmental Information Processing Signal transduction hsa04630 JAK-STAT signaling pathway 2/202 168/9376 0.552569542668553 PDGFA/CCND1 -0.868319360703462 Genetic Information Processing Folding, sorting and degradation hsa04141 Protein processing in endoplasmic reticulum 2/202 174/9376 0.533515420507568 TUSC3/SEC31A -0.921621837423179 Environmental Information Processing Signal transduction hsa04064 NF-kappa B signaling pathway 1/202 105/9376 0.442055634134842 PLCG2 -0.853108384787464 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 2/202 180/9376 0.515731573157316 HLA-B/CCL2 -0.973430346746187 Organismal Systems Immune system hsa04620 Toll-like receptor signaling pathway 1/202 109/9376 0.425833409028976 MAP2K3 -0.894671372467483 Organismal Systems Endocrine system hsa04914 Progesterone-mediated oocyte maturation 1/202 110/9376 0.421962196219622 CPEB3 -0.904874588131647 Organismal Systems Nervous system hsa04726 Serotonergic synapse 1/202 115/9376 0.403616013775291 CACNA1C -0.954834069278617 Human Diseases Substance dependence hsa05034 Alcoholism 2/202 191/9376 0.486029754807942 BDNF/CREB3L1 -1.06487108810921 Metabolism Global and overview maps hsa01200 Carbon metabolism 1/202 116/9376 0.400136565380676 IDH2 -0.964623518181016 Organismal Systems Nervous system hsa04724 Glutamatergic synapse 1/202 116/9376 0.400136565380676 CACNA1C -0.964623518181016 Human Diseases Neurodegenerative disease hsa05012 Parkinson disease 3/202 268/9376 0.519580316240579 MT-ND3/CAMK2G/NDUFA4L2 -1.18401889775557 Human Diseases Infectious disease: viral hsa05162 Measles 1/202 136/9376 0.341292952824694 CCND1 -1.14817406654104 NA NA hsa04081 Hormone signaling 2/202 219/9376 0.42388896423889 PRKG1/BMPR1A -1.28006964735873 Organismal Systems Endocrine system hsa04915 Estrogen signaling pathway 1/202 139/9376 0.333926917871643 CREB3L1 -1.17393963666491 Human Diseases Neurodegenerative disease hsa05017 Spinocerebellar ataxia 1/202 144/9376 0.322332233223322 ATXN1 -1.21599596017196 Human Diseases Neurodegenerative disease hsa05014 Amyotrophic lateral sclerosis 4/202 368/9376 0.504520017219113 MT-ND3/NDUFA4L2/MAP2K3/CHCHD10 -1.43885751509071 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 2/202 238/9376 0.390049088942508 PLCG2/CCL2 -1.41429413709084 Human Diseases Infectious disease: viral hsa05160 Hepatitis C 1/202 156/9376 0.297537446052298 CCND1 -1.31281028965261 Environmental Information Processing Signal transduction hsa04150 mTOR signaling pathway 1/202 158/9376 0.293771149266825 FNIP2 -1.32842671845726 Human Diseases Neurodegenerative disease hsa05010 Alzheimer disease 4/202 388/9376 0.47851383076452 MT-ND3/CACNA1C/NDUFA4L2/NOX4 -1.55671489399599 Cellular Processes Transport and catabolism hsa04142 Lysosome biogenesis 2/202 250/9376 0.371326732673267 SORT1/SLC2A6 -1.49498460581529 Cellular Processes Cell growth and death hsa04217 Necroptosis 1/202 168/9376 0.276284771334276 CAMK2G -1.40449970356145 Cellular Processes Transport and catabolism hsa04140 Autophagy - animal 1/202 169/9376 0.274649950202121 BIRC6 -1.41193232438317 Human Diseases Infectious disease: viral hsa05164 Influenza A 1/202 173/9376 0.268299662336176 CCL2 -1.44136360258545 Organismal Systems Immune system hsa04613 Neutrophil extracellular trap formation 1/202 195/9376 0.238029956841838 PLCG2 -1.59548293862186 Organismal Systems Sensory system hsa04740 Olfactory transduction 4/202 449/9376 0.413504156651745 PRKG1/NCALD/SLC8A1/CAMK2G -1.88980631823075 Genetic Information Processing Transcription hsa03040 Spliceosome 1/202 243/9376 0.191011693761969 DDX46 -1.89592261523294 Environmental Information Processing Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction 2/202 370/9376 0.250896440995451 NR3C1/PTGER4 -2.1815175248218