ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003779	actin binding	145/2914	443/18639	0.327313769751693	2.09361748606788	1.17397081830778e-19	1.55433736343949e-16
GO:0005201	extracellular matrix structural constituent	67/2914	168/18639	0.398809523809524	2.55093023825865	2.53089785504991e-14	1.67545438004304e-11
GO:0051015	actin filament binding	74/2914	209/18639	0.354066985645933	2.2647407499844	1.47559558573948e-12	6.51229518506357e-10
GO:0045296	cadherin binding	97/2914	334/18639	0.290419161676647	1.85762620263933	3.02392168965119e-10	1.00091807927454e-07
GO:0019838	growth factor binding	46/2914	136/18639	0.338235294117647	2.16347551374702	1.16335033890128e-07	3.08055169741059e-05
GO:0005178	integrin binding	51/2914	161/18639	0.316770186335404	2.02617690566424	2.61270877204241e-07	5.76537735697359e-05
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	28/2914	68/18639	0.411764705882353	2.63379627760507	3.79101413901789e-07	6.84396960089663e-05
GO:0005518	collagen binding	29/2914	72/18639	0.402777777777778	2.57631262868909	4.13532906398588e-07	6.84396960089663e-05
GO:0004674	protein serine/threonine kinase activity	107/2914	433/18639	0.247113163972286	1.58062534772802	4.97160657905873e-07	7.3137856785264e-05
GO:0003954	NADH dehydrogenase activity	21/2914	44/18639	0.477272727272727	3.05280932176951	5.69725961816297e-07	7.54317173444777e-05
GO:0009055	electron transfer activity	39/2914	116/18639	0.336206896551724	2.15050114784749	1.23473955226917e-06	0.000148617742473126
GO:0031267	small GTPase binding	75/2914	283/18639	0.265017667844523	1.6951490428806	1.62576023717682e-06	0.00017937554616851
GO:0008137	NADH dehydrogenase (ubiquinone) activity	19/2914	41/18639	0.463414634146341	2.96416793611999	3.42592730118485e-06	0.00034891751898221
GO:0051020	GTPase binding	80/2914	315/18639	0.253968253968254	1.6244729875478	4.44223628247052e-06	0.000420108631285069
GO:0106310	protein serine kinase activity	89/2914	361/18639	0.246537396121884	1.57694252790521	4.88939759315879e-06	0.00043157082755615
GO:1901505	carbohydrate derivative transmembrane transporter activity	22/2914	53/18639	0.415094339622642	2.65509382162883	5.64153245347512e-06	0.000466836810525067
GO:0015932	nucleobase-containing compound transmembrane transporter activity	23/2914	57/18639	0.403508771929825	2.58098833218943	6.16873726344942e-06	0.000480435772753355
GO:0140297	DNA-binding transcription factor binding	113/2914	488/18639	0.23155737704918	1.48112489733002	6.86080414336339e-06	0.000487616766743788
GO:0000287	magnesium ion binding	62/2914	230/18639	0.269565217391304	1.72423681776133	6.99752157713896e-06	0.000487616766743788
GO:0004721	phosphoprotein phosphatase activity	50/2914	175/18639	0.285714285714286	1.82753211099127	9.494929905491e-06	0.000628564359743504
GO:0141003	histone H2AX kinase activity	86/2914	354/18639	0.242937853107345	1.55391854635134	1.28203740922954e-05	0.000808294061819006
GO:0035173	histone kinase activity	87/2914	360/18639	0.241666666666667	1.54578757721345	1.41771101455184e-05	0.000853204265121197
GO:0140996	histone H3 kinase activity	86/2914	357/18639	0.240896358543417	1.54086040730637	1.79972335131045e-05	0.000905334485935854
GO:0035402	histone H3T11 kinase activity	64/2914	247/18639	0.259109311740891	1.65735705612164	1.97807637975532e-05	0.000905334485935854
GO:0004679	AMP-activated protein kinase activity	64/2914	248/18639	0.258064516129032	1.65067416476631	2.26537354786668e-05	0.000905334485935854
GO:0015605	organophosphate ester transmembrane transporter activity	20/2914	50/18639	0.4	2.55854495538778	2.86212714141206e-05	0.000905334485935854
GO:0004676	3-phosphoinositide-dependent protein kinase activity	63/2914	245/18639	0.257142857142857	1.64477889989215	2.94028571716327e-05	0.000905334485935854
GO:0004711	ribosomal protein S6 kinase activity	63/2914	245/18639	0.257142857142857	1.64477889989215	2.94028571716327e-05	0.000905334485935854
GO:0035175	histone H3S10 kinase activity	63/2914	245/18639	0.257142857142857	1.64477889989215	2.94028571716327e-05	0.000905334485935854
GO:0035979	histone H2AXS139 kinase activity	63/2914	245/18639	0.257142857142857	1.64477889989215	2.94028571716327e-05	0.000905334485935854
GO:0044022	histone H3S28 kinase activity	63/2914	245/18639	0.257142857142857	1.64477889989215	2.94028571716327e-05	0.000905334485935854
GO:0044023	histone H4S1 kinase activity	63/2914	245/18639	0.257142857142857	1.64477889989215	2.94028571716327e-05	0.000905334485935854
GO:0044024	histone H2AS1 kinase activity	63/2914	245/18639	0.257142857142857	1.64477889989215	2.94028571716327e-05	0.000905334485935854
GO:0044025	histone H2BS14 kinase activity	63/2914	245/18639	0.257142857142857	1.64477889989215	2.94028571716327e-05	0.000905334485935854
GO:0072354	histone H3T3 kinase activity	63/2914	245/18639	0.257142857142857	1.64477889989215	2.94028571716327e-05	0.000905334485935854
GO:0072371	histone H2AS121 kinase activity	63/2914	245/18639	0.257142857142857	1.64477889989215	2.94028571716327e-05	0.000905334485935854
GO:0072518	Rho-dependent protein serine/threonine kinase activity	63/2914	245/18639	0.257142857142857	1.64477889989215	2.94028571716327e-05	0.000905334485935854
GO:0140823	histone H2BS36 kinase activity	63/2914	245/18639	0.257142857142857	1.64477889989215	2.94028571716327e-05	0.000905334485935854
GO:0140855	histone H3S57 kinase activity	63/2914	245/18639	0.257142857142857	1.64477889989215	2.94028571716327e-05	0.000905334485935854
GO:0140995	histone H2A kinase activity	63/2914	245/18639	0.257142857142857	1.64477889989215	2.94028571716327e-05	0.000905334485935854
GO:0140997	histone H4 kinase activity	63/2914	245/18639	0.257142857142857	1.64477889989215	2.94028571716327e-05	0.000905334485935854
GO:0140998	histone H2B kinase activity	63/2914	245/18639	0.257142857142857	1.64477889989215	2.94028571716327e-05	0.000905334485935854
GO:1990244	histone H2AT120 kinase activity	63/2914	245/18639	0.257142857142857	1.64477889989215	2.94028571716327e-05	0.000905334485935854
GO:0004677	DNA-dependent protein kinase activity	63/2914	246/18639	0.25609756097561	1.63809280680315	3.35872751988569e-05	0.000968602015568272
GO:0140857	histone H3T45 kinase activity	63/2914	246/18639	0.25609756097561	1.63809280680315	3.35872751988569e-05	0.000968602015568272
GO:0022804	active transmembrane transporter activity	104/2914	457/18639	0.227571115973742	1.45562732691646	3.36523358883236e-05	0.000968602015568272
GO:0035403	histone H3T6 kinase activity	63/2914	247/18639	0.255060728744939	1.63146085211974	3.83145046460426e-05	0.00107932774790129
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	62/2914	243/18639	0.255144032921811	1.63199369582348	4.34988576137816e-05	0.00119984348918014
GO:0015399	primary active transmembrane transporter activity	46/2914	166/18639	0.27710843373494	1.77248596306985	4.88939527686376e-05	0.001321134560524
GO:0044548	S100 protein binding	9/2914	14/18639	0.642857142857143	4.11194724973037	5.20398611976911e-05	0.00137801552451486
GO:0005525	GTP binding	88/2914	378/18639	0.232804232804233	1.48910023858548	5.58374125881454e-05	0.00144958302483734
GO:0022853	active monoatomic ion transmembrane transporter activity	35/2914	118/18639	0.296610169491525	1.89722613217314	8.59614519535193e-05	0.00218871081512422
GO:0050431	transforming growth factor beta binding	12/2914	24/18639	0.5	3.19818119423473	8.87729048919032e-05	0.00221764766182792
GO:0035615	clathrin adaptor activity	10/2914	18/18639	0.555555555555556	3.55353466026081	0.00011166295466701	0.00273781022183557
GO:0031625	ubiquitin protein ligase binding	72/2914	302/18639	0.23841059602649	1.52496056943643	0.000117637051957772	0.00283184466894708
GO:0050840	extracellular matrix binding	23/2914	67/18639	0.343283582089552	2.19576619305668	0.000125980266559552	0.00297853344508655
GO:0004725	protein tyrosine phosphatase activity	30/2914	98/18639	0.306122448979592	1.95807011891922	0.000143649993440121	0.00333671212832843
GO:0019001	guanyl nucleotide binding	90/2914	400/18639	0.225	1.43918153740563	0.000167880904921281	0.00376736132399621
GO:0032561	guanyl ribonucleotide binding	90/2914	400/18639	0.225	1.43918153740563	0.000167880904921281	0.00376736132399621
GO:0005543	phospholipid binding	108/2914	497/18639	0.217303822937626	1.38995399990886	0.000170808697189827	0.00376917858465551
GO:0050321	tau-protein kinase activity	11/2914	22/18639	0.5	3.19818119423473	0.000175641572543971	0.00381228593521669
GO:0030020	extracellular matrix structural constituent conferring tensile strength	17/2914	44/18639	0.386363636363636	2.47132183190865	0.000186221645184119	0.00397673319715765
GO:0015078	proton transmembrane transporter activity	48/2914	185/18639	0.259459459459459	1.6595967278191	0.00019680231918481	0.00412908164537617
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	80/2914	349/18639	0.229226361031519	1.46621487414773	0.000202206589993886	0.00412908164537617
GO:0005346	purine ribonucleotide transmembrane transporter activity	10/2914	19/18639	0.526315789473684	3.36650652024708	0.00020271171219747	0.00412908164537617
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	36/2914	128/18639	0.28125	1.79897692175704	0.000223983610670096	0.00449324697768496
GO:0016504	peptidase activator activity	20/2914	57/18639	0.350877192982456	2.24433768016472	0.000243906868006028	0.00481989094388031
GO:0035091	phosphatidylinositol binding	67/2914	284/18639	0.235915492957746	1.50900098601216	0.000273839742207494	0.0053318208629812
GO:0046332	SMAD binding	25/2914	79/18639	0.316455696202532	2.02416531280679	0.000282799793421687	0.0054264771955118
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	20/2914	58/18639	0.344827586206897	2.2056422029205	0.000318139812009434	0.00601738730143558
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	19/2914	54/18639	0.351851851851852	2.25057195149851	0.000332165451219279	0.00617995877451792
GO:0003714	transcription corepressor activity	51/2914	204/18639	0.25	1.59909059711736	0.000336070265683754	0.00617995877451792
GO:1901981	phosphatidylinositol phosphate binding	47/2914	185/18639	0.254054054054054	1.62502179598954	0.000382556612408338	0.00693842403874849
GO:0048407	platelet-derived growth factor binding	7/2914	11/18639	0.636363636363636	4.07041242902602	0.000417237399767116	0.00736563089722215
GO:0097493	structural molecule activity conferring elasticity	7/2914	11/18639	0.636363636363636	4.07041242902602	0.000417237399767116	0.00736563089722215
GO:0003924	GTPase activity	75/2914	331/18639	0.226586102719033	1.4493268251819	0.000451739886693709	0.00778825433819473
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	11/2914	24/18639	0.458333333333333	2.93166609471517	0.000458824651343798	0.00778825433819473
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	11/2914	24/18639	0.458333333333333	2.93166609471517	0.000458824651343798	0.00778825433819473
GO:0048156	tau protein binding	16/2914	43/18639	0.372093023255814	2.38004181896538	0.000471335198911976	0.00789933928303109
GO:0044389	ubiquitin-like protein ligase binding	73/2914	322/18639	0.226708074534162	1.45010700111264	0.000525135888399066	0.00869099895300454
GO:0140312	cargo adaptor activity	10/2914	21/18639	0.476190476190476	3.04588685165212	0.000572795013501183	0.00936272343056254
GO:0016651	oxidoreductase activity, acting on NAD(P)H	26/2914	88/18639	0.295454545454545	1.88983434204779	0.000708262663286913	0.011435850807218
GO:0016791	phosphatase activity	63/2914	273/18639	0.230769230769231	1.47608362810834	0.000755722564728699	0.012055140671094
GO:0044325	transmembrane transporter binding	36/2914	136/18639	0.264705882352941	1.69315474988897	0.000785557496635529	0.0121619718517075
GO:0140789	histone phosphatase activity	36/2914	136/18639	0.264705882352941	1.69315474988897	0.000785557496635529	0.0121619718517075
GO:0004860	protein kinase inhibitor activity	25/2914	84/18639	0.297619047619048	1.90367928228258	0.000789977023600333	0.0121619718517075
GO:0071889	14-3-3 protein binding	13/2914	33/18639	0.393939393939394	2.51977912273039	0.000846106866081629	0.0128763849504836
GO:0005078	MAP-kinase scaffold activity	7/2914	12/18639	0.583333333333333	3.73121139327385	0.00086606607551884	0.0128839492582803
GO:0031543	peptidyl-proline dioxygenase activity	7/2914	12/18639	0.583333333333333	3.73121139327385	0.00086606607551884	0.0128839492582803
GO:0061133	endopeptidase activator activity	10/2914	22/18639	0.454545454545455	2.9074374493043	0.00090375621429886	0.0132952580859077
GO:0019210	kinase inhibitor activity	26/2914	90/18639	0.288888888888889	1.84783802333562	0.00102509680294701	0.0149145952428774
GO:0004112	cyclic-nucleotide phosphodiesterase activity	11/2914	26/18639	0.423076923076923	2.70615331819862	0.00104946640899311	0.0149407905968481
GO:0015216	purine nucleotide transmembrane transporter activity	11/2914	26/18639	0.423076923076923	2.70615331819862	0.00104946640899311	0.0149407905968481
GO:0001968	fibronectin binding	12/2914	30/18639	0.4	2.55854495538778	0.00113675118607008	0.0154335625581335
GO:0015215	nucleotide transmembrane transporter activity	12/2914	30/18639	0.4	2.55854495538778	0.00113675118607008	0.0154335625581335
GO:0003756	protein disulfide isomerase activity	9/2914	19/18639	0.473684210526316	3.02985586822237	0.00113859891335498	0.0154335625581335
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	9/2914	19/18639	0.473684210526316	3.02985586822237	0.00113859891335498	0.0154335625581335
GO:0042578	phosphoric ester hydrolase activity	79/2914	363/18639	0.21763085399449	1.39204580906085	0.00114236339176517	0.0154335625581335
GO:0043531	ADP binding	14/2914	38/18639	0.368421052631579	2.35655456417296	0.0011774699618892	0.0157471740357707
GO:0000295	adenine nucleotide transmembrane transporter activity	10/2914	23/18639	0.434782608695652	2.7810271254215	0.00137647822461592	0.0180441303900147
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	10/2914	23/18639	0.434782608695652	2.7810271254215	0.00137647822461592	0.0180441303900147
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	24/2914	83/18639	0.289156626506024	1.84955057015984	0.00154893906515608	0.0201058364928103
GO:0060589	nucleoside-triphosphatase regulator activity	101/2914	490/18639	0.206122448979592	1.31843388007228	0.00177434799543824	0.0228081237471867
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	25/2914	89/18639	0.280898876404494	1.79673100799704	0.00195263816703502	0.024621837458613
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	25/2914	89/18639	0.280898876404494	1.79673100799704	0.00195263816703502	0.024621837458613
GO:0015036	disulfide oxidoreductase activity	14/2914	40/18639	0.35	2.23872683596431	0.00207991698615524	0.0259793404685806
GO:0140793	histone H2AXY142 phosphatase activity	25/2914	90/18639	0.277777777777778	1.7767673301304	0.00230938484553041	0.0276987149083968
GO:0035591	signaling adaptor activity	33/2914	129/18639	0.255813953488372	1.6362787505387	0.00233600954972751	0.0276987149083968
GO:0019902	phosphatase binding	45/2914	190/18639	0.236842105263158	1.51492793411119	0.00234445425812306	0.0276987149083968
GO:0030695	GTPase regulator activity	100/2914	489/18639	0.204498977505112	1.30804956819416	0.00240759334950133	0.0276987149083968
GO:0016853	isomerase activity	43/2914	180/18639	0.238888888888889	1.52801990391215	0.0024321960411195	0.0276987149083968
GO:0033192	calmodulin-dependent protein phosphatase activity	23/2914	81/18639	0.283950617283951	1.81625104857775	0.00248953706502962	0.0276987149083968
GO:0140791	histone H2AXS140 phosphatase activity	23/2914	81/18639	0.283950617283951	1.81625104857775	0.00248953706502962	0.0276987149083968
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	23/2914	81/18639	0.283950617283951	1.81625104857775	0.00248953706502962	0.0276987149083968
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	23/2914	81/18639	0.283950617283951	1.81625104857775	0.00248953706502962	0.0276987149083968
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	23/2914	81/18639	0.283950617283951	1.81625104857775	0.00248953706502962	0.0276987149083968
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	23/2914	81/18639	0.283950617283951	1.81625104857775	0.00248953706502962	0.0276987149083968
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	23/2914	81/18639	0.283950617283951	1.81625104857775	0.00248953706502962	0.0276987149083968
GO:1990439	MAP kinase serine/threonine phosphatase activity	23/2914	81/18639	0.283950617283951	1.81625104857775	0.00248953706502962	0.0276987149083968
GO:0001221	transcription coregulator binding	30/2914	115/18639	0.260869565217391	1.6686162752529	0.00261894525020836	0.0288956959272989
GO:0051287	NAD binding	17/2914	54/18639	0.314814814814815	2.01366964081446	0.00270500736981482	0.0295985930383043
GO:0005096	GTPase activator activity	60/2914	271/18639	0.22140221402214	1.41616879449508	0.00279265059027179	0.0302578133751409
GO:0005347	ATP transmembrane transporter activity	7/2914	14/18639	0.5	3.19818119423473	0.00281096000388393	0.0302578133751409
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	23/2914	82/18639	0.280487804878049	1.79410164554631	0.00295754488143928	0.0313263153842048
GO:0033549	MAP kinase phosphatase activity	23/2914	82/18639	0.280487804878049	1.79410164554631	0.00295754488143928	0.0313263153842048
GO:0002020	protease binding	34/2914	136/18639	0.25	1.59909059711736	0.00303637595254049	0.0319060457235207
GO:0030276	clathrin binding	15/2914	46/18639	0.326086956521739	2.08577034406613	0.00322975977717482	0.0335311543114058
GO:0005536	D-glucose binding	6/2914	11/18639	0.545454545454545	3.48892493916516	0.00329233388253985	0.0335311543114058
GO:0008432	JUN kinase binding	6/2914	11/18639	0.545454545454545	3.48892493916516	0.00329233388253985	0.0335311543114058
GO:0034713	type I transforming growth factor beta receptor binding	6/2914	11/18639	0.545454545454545	3.48892493916516	0.00329233388253985	0.0335311543114058
GO:0003712	transcription coregulator activity	100/2914	495/18639	0.202020202020202	1.29219442191302	0.00353484729486559	0.0357262428885652
GO:0004722	protein serine/threonine phosphatase activity	27/2914	103/18639	0.262135922330097	1.67671635425898	0.00387361734411383	0.0388535557848993
GO:0016881	acid-amino acid ligase activity	9/2914	22/18639	0.409090909090909	2.61669370437387	0.00393324525597622	0.0391550129241543
GO:0017018	myosin phosphatase activity	23/2914	84/18639	0.273809523809524	1.75138493969997	0.00411775127941501	0.0406858409995931
GO:0019955	cytokine binding	35/2914	144/18639	0.243055555555556	1.5546714138641	0.00434952149552035	0.042657529333844
GO:0004129	cytochrome-c oxidase activity	7/2914	15/18639	0.466666666666667	2.98496911461908	0.0045644766719299	0.0441121687126656
GO:0005523	tropomyosin binding	7/2914	15/18639	0.466666666666667	2.98496911461908	0.0045644766719299	0.0441121687126656
GO:0048306	calcium-dependent protein binding	22/2914	80/18639	0.275	1.7589996568291	0.0046770618432979	0.0448726802936697
GO:0008194	UDP-glycosyltransferase activity	35/2914	145/18639	0.241379310344828	1.54394954204435	0.00489022928300371	0.0465803134582511
GO:0004713	protein tyrosine kinase activity	34/2914	140/18639	0.242857142857143	1.55340229434258	0.0049598212745744	0.0469057383395464
GO:0016757	glycosyltransferase activity	58/2914	267/18639	0.217228464419476	1.38947197951771	0.00499663486267184	0.0469187557317555
GO:0016879	ligase activity, forming carbon-nitrogen bonds	15/2914	48/18639	0.3125	1.99886324639671	0.00507922763024683	0.0473584322707522
GO:0001618	virus receptor activity	22/2914	81/18639	0.271604938271605	1.73728361168306	0.00549274904875386	0.0508559422416092
GO:0005158	insulin receptor binding	9/2914	23/18639	0.391304347826087	2.50292441287935	0.00557688120470786	0.0512763244099528
GO:0031072	heat shock protein binding	32/2914	131/18639	0.244274809160305	1.56247020176353	0.00572968164830734	0.0523179207059235
GO:1902936	phosphatidylinositol bisphosphate binding	28/2914	111/18639	0.252252252252252	1.61349681871302	0.00589184489399702	0.05343015506611
GO:0061134	peptidase regulator activity	50/2914	226/18639	0.221238938053097	1.41512442222776	0.00603206868243845	0.0543296526227789
GO:0071949	FAD binding	13/2914	40/18639	0.325	2.07881777625257	0.00612228210312393	0.0547696047603789
GO:0140272	exogenous protein binding	22/2914	82/18639	0.268292682926829	1.71609722617473	0.00642232391010253	0.0570681668253406
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	30/2914	122/18639	0.245901639344262	1.57287599716462	0.00661232973005267	0.0583648304172649
GO:0016675	oxidoreductase activity, acting on a heme group of donors	7/2914	16/18639	0.4375	2.79840854495539	0.00703083025437534	0.0616478096476355
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	10/2914	28/18639	0.357142857142857	2.28441513873909	0.00749844592631687	0.0653154105687075
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	13/2914	41/18639	0.317073170731707	2.02811490366105	0.00770635655198115	0.0666876867635493
GO:0051117	ATPase binding	22/2914	84/18639	0.261904761904762	1.67523776840867	0.00866922812879566	0.0745328444319835
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	17/2914	60/18639	0.283333333333333	1.81230267673301	0.00881120228120238	0.0752647214213674
GO:0015297	antiporter activity	32/2914	135/18639	0.237037037037037	1.51617478837795	0.00910482128168404	0.077274252416344
GO:0005338	nucleotide-sugar transmembrane transporter activity	6/2914	13/18639	0.461538461538462	2.95216725621667	0.00922857602714116	0.0778256984709229
GO:0005539	glycosaminoglycan binding	52/2914	242/18639	0.214876033057851	1.37442497603476	0.00935060862996089	0.0783557330763811
GO:0019211	phosphatase activator activity	9/2914	25/18639	0.36	2.302690459849	0.0103963947090193	0.0865712364449156
GO:0030159	signaling receptor complex adaptor activity	15/2914	52/18639	0.288461538461538	1.84510453513542	0.0113095268862587	0.0931361779326324
GO:0016922	nuclear receptor binding	32/2914	137/18639	0.233576642335766	1.49404084986148	0.0113254717878805	0.0931361779326324
GO:0008376	acetylgalactosaminyltransferase activity	11/2914	34/18639	0.323529411764706	2.06941136097541	0.0117128884796976	0.093290035752085
GO:0015035	protein-disulfide reductase activity	11/2914	34/18639	0.323529411764706	2.06941136097541	0.0117128884796976	0.093290035752085
GO:0001094	TFIID-class transcription factor complex binding	5/2914	10/18639	0.5	3.19818119423473	0.0117669455971285	0.093290035752085
GO:0005522	profilin binding	5/2914	10/18639	0.5	3.19818119423473	0.0117669455971285	0.093290035752085
GO:0005528	FK506 binding	5/2914	10/18639	0.5	3.19818119423473	0.0117669455971285	0.093290035752085
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	5/2914	10/18639	0.5	3.19818119423473	0.0117669455971285	0.093290035752085
GO:0005516	calmodulin binding	45/2914	207/18639	0.217391304347826	1.39051356271075	0.0120716899367105	0.0951364135488375
GO:0016758	hexosyltransferase activity	43/2914	197/18639	0.218274111675127	1.39616031829536	0.0129675889238467	0.101592235119367
GO:0016860	intramolecular oxidoreductase activity	15/2914	53/18639	0.283018867924528	1.81029124201966	0.0135489776188932	0.105139896145977
GO:0019903	protein phosphatase binding	33/2914	144/18639	0.229166666666667	1.46583304735758	0.0135866115704969	0.105139896145977
GO:0005160	transforming growth factor beta receptor binding	9/2914	26/18639	0.346153846153846	2.2141254421625	0.0137380680009471	0.105139896145977
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	9/2914	26/18639	0.346153846153846	2.2141254421625	0.0137380680009471	0.105139896145977
GO:0016530	metallochaperone activity	6/2914	14/18639	0.428571428571429	2.74129816648691	0.0140417880445841	0.106236156405882
GO:0034236	protein kinase A catalytic subunit binding	6/2914	14/18639	0.428571428571429	2.74129816648691	0.0140417880445841	0.106236156405882
GO:0051087	protein-folding chaperone binding	31/2914	134/18639	0.23134328358209	1.4797554779295	0.0143496233002349	0.10794830255404
GO:0005507	copper ion binding	17/2914	63/18639	0.26984126984127	1.72600254926954	0.0145524904472083	0.108157794341279
GO:1901682	sulfur compound transmembrane transporter activity	17/2914	63/18639	0.26984126984127	1.72600254926954	0.0145524904472083	0.108157794341279
GO:0008525	phosphatidylcholine transporter activity	7/2914	18/18639	0.388888888888889	2.48747426218257	0.0147042318590862	0.108157794341279
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	7/2914	18/18639	0.388888888888889	2.48747426218257	0.0147042318590862	0.108157794341279
GO:0004197	cysteine-type endopeptidase activity	22/2914	88/18639	0.25	1.59909059711736	0.0150642277657863	0.110193577690061
GO:0001222	transcription corepressor binding	14/2914	49/18639	0.285714285714286	1.82753211099127	0.0153956978006777	0.111999471912622
GO:0001786	phosphatidylserine binding	16/2914	59/18639	0.271186440677966	1.73460674941545	0.0166444304520632	0.119767532165933
GO:0045309	protein phosphorylated amino acid binding	16/2914	59/18639	0.271186440677966	1.73460674941545	0.0166444304520632	0.119767532165933
GO:0048029	monosaccharide binding	19/2914	74/18639	0.256756756756757	1.64230926190432	0.0173358074820624	0.124068157331085
GO:0004683	calcium/calmodulin-dependent protein kinase activity	9/2914	27/18639	0.333333333333333	2.13212079615649	0.0178115832436079	0.126787829110413
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	11/2914	36/18639	0.305555555555556	1.95444406314345	0.0182783879711251	0.127844910576211
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	11/2914	36/18639	0.305555555555556	1.95444406314345	0.0182783879711251	0.127844910576211
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	11/2914	36/18639	0.305555555555556	1.95444406314345	0.0182783879711251	0.127844910576211
GO:0005114	type II transforming growth factor beta receptor binding	5/2914	11/18639	0.454545454545455	2.9074374493043	0.0188291220259525	0.127844910576211
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	5/2914	11/18639	0.454545454545455	2.9074374493043	0.0188291220259525	0.127844910576211
GO:0015217	ADP transmembrane transporter activity	5/2914	11/18639	0.454545454545455	2.9074374493043	0.0188291220259525	0.127844910576211
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	5/2914	11/18639	0.454545454545455	2.9074374493043	0.0188291220259525	0.127844910576211
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	5/2914	11/18639	0.454545454545455	2.9074374493043	0.0188291220259525	0.127844910576211
GO:0048185	activin binding	5/2914	11/18639	0.454545454545455	2.9074374493043	0.0188291220259525	0.127844910576211
GO:0140313	molecular sequestering activity	15/2914	55/18639	0.272727272727273	1.74446246958258	0.0190444188032901	0.128646992324266
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	30/2914	132/18639	0.227272727272727	1.45371872465215	0.0200547064184258	0.134783915218253
GO:0031005	filamin binding	6/2914	15/18639	0.4	2.55854495538778	0.0203599956263535	0.135460473413528
GO:0051371	muscle alpha-actinin binding	6/2914	15/18639	0.4	2.55854495538778	0.0203599956263535	0.135460473413528
GO:0030291	protein serine/threonine kinase inhibitor activity	13/2914	46/18639	0.282608695652174	1.80766763152398	0.0209715228895908	0.138831481529091
GO:0008017	microtubule binding	56/2914	276/18639	0.202898550724638	1.29781265853003	0.022234841445979	0.146340270554551
GO:0043394	proteoglycan binding	11/2914	37/18639	0.297297297297297	1.90162125062606	0.0224336566441603	0.146340270554551
GO:0005200	structural constituent of cytoskeleton	26/2914	112/18639	0.232142857142857	1.48486984018041	0.0224880189822126	0.146340270554551
GO:0046875	ephrin receptor binding	9/2914	28/18639	0.321428571428571	2.05597362486518	0.0226967535517985	0.146340270554551
GO:0097718	disordered domain specific binding	9/2914	28/18639	0.321428571428571	2.05597362486518	0.0226967535517985	0.146340270554551
GO:0140034	methylation-dependent protein binding	19/2914	76/18639	0.25	1.59909059711736	0.0227689544820525	0.146340270554551
GO:0140104	molecular carrier activity	51/2914	249/18639	0.204819277108434	1.31009832052989	0.0238737542233923	0.151465606790127
GO:0016859	cis-trans isomerase activity	12/2914	42/18639	0.285714285714286	1.82753211099127	0.0239096010718555	0.151465606790127
GO:0019894	kinesin binding	12/2914	42/18639	0.285714285714286	1.82753211099127	0.0239096010718555	0.151465606790127
GO:0005540	hyaluronic acid binding	8/2914	24/18639	0.333333333333333	2.13212079615649	0.0249515552479187	0.155829524284172
GO:0035035	histone acetyltransferase binding	8/2914	24/18639	0.333333333333333	2.13212079615649	0.0249515552479187	0.155829524284172
GO:0070300	phosphatidic acid binding	8/2914	24/18639	0.333333333333333	2.13212079615649	0.0249515552479187	0.155829524284172
GO:0140416	transcription regulator inhibitor activity	10/2914	33/18639	0.303030303030303	1.93829163286953	0.0253232499402278	0.157408370520477
GO:0005080	protein kinase C binding	14/2914	52/18639	0.269230769230769	1.72209756612639	0.0256628616336646	0.158187867060497
GO:0016874	ligase activity	36/2914	167/18639	0.215568862275449	1.37885656278384	0.0256876068111834	0.158187867060497
GO:0004857	enzyme inhibitor activity	80/2914	416/18639	0.192307692307692	1.23006969009028	0.0264424062403849	0.162082156769767
GO:0031418	L-ascorbic acid binding	7/2914	20/18639	0.35	2.23872683596431	0.0269827410783907	0.164632023906863
GO:0000146	microfilament motor activity	11/2914	38/18639	0.289473684210526	1.8515785861359	0.0272392765640121	0.165316799893869
GO:0051213	dioxygenase activity	22/2914	93/18639	0.236559139784946	1.51311798436912	0.0277380478468664	0.165316799893869
GO:0005527	macrolide binding	5/2914	12/18639	0.416666666666667	2.66515099519561	0.0281937794090893	0.165316799893869
GO:0017166	vinculin binding	5/2914	12/18639	0.416666666666667	2.66515099519561	0.0281937794090893	0.165316799893869
GO:0035259	nuclear glucocorticoid receptor binding	5/2914	12/18639	0.416666666666667	2.66515099519561	0.0281937794090893	0.165316799893869
GO:0035497	cAMP response element binding	5/2914	12/18639	0.416666666666667	2.66515099519561	0.0281937794090893	0.165316799893869
GO:0141221	histone deacetylase activity, hydrolytic mechanism	5/2914	12/18639	0.416666666666667	2.66515099519561	0.0281937794090893	0.165316799893869
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	6/2914	16/18639	0.375	2.39863589567605	0.0283574948495405	0.165316799893869
GO:0031435	mitogen-activated protein kinase kinase kinase binding	6/2914	16/18639	0.375	2.39863589567605	0.0283574948495405	0.165316799893869
GO:0003785	actin monomer binding	9/2914	29/18639	0.310344827586207	1.98507798262845	0.0284684519454699	0.165316799893869
GO:0043236	laminin binding	9/2914	29/18639	0.310344827586207	1.98507798262845	0.0284684519454699	0.165316799893869
GO:1901681	sulfur compound binding	55/2914	275/18639	0.2	1.27927247769389	0.0300014662969557	0.171543184674225
GO:0051018	protein kinase A binding	14/2914	53/18639	0.264150943396226	1.68960515921835	0.0300114353825569	0.171543184674225
GO:0140296	general transcription initiation factor binding	14/2914	53/18639	0.264150943396226	1.68960515921835	0.0300114353825569	0.171543184674225
GO:0005548	phospholipid transporter activity	17/2914	68/18639	0.25	1.59909059711736	0.0301229398755362	0.171543184674225
GO:0005085	guanyl-nucleotide exchange factor activity	47/2914	230/18639	0.204347826086957	1.30708274894811	0.0301884909585306	0.171543184674225
GO:0008139	nuclear localization sequence binding	8/2914	25/18639	0.32	2.04683596431023	0.031801042560342	0.179934104059371
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	11/2914	39/18639	0.282051282051282	1.80410221213241	0.0327433347503417	0.184477341316819
GO:0035064	methylated histone binding	18/2914	74/18639	0.243243243243243	1.55587193233041	0.033838041001512	0.189837145279669
GO:0009975	cyclase activity	7/2914	21/18639	0.333333333333333	2.13212079615649	0.0351571011837611	0.192552907901414
GO:0019200	carbohydrate kinase activity	7/2914	21/18639	0.333333333333333	2.13212079615649	0.0351571011837611	0.192552907901414
GO:0070182	DNA polymerase binding	7/2914	21/18639	0.333333333333333	2.13212079615649	0.0351571011837611	0.192552907901414
GO:0072542	protein phosphatase activator activity	7/2914	21/18639	0.333333333333333	2.13212079615649	0.0351571011837611	0.192552907901414
GO:0008106	alcohol dehydrogenase (NADP+) activity	9/2914	30/18639	0.3	1.91890871654084	0.0351947157946693	0.192552907901414
GO:0016769	transferase activity, transferring nitrogenous groups	9/2914	30/18639	0.3	1.91890871654084	0.0351947157946693	0.192552907901414
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	6/2914	17/18639	0.352941176470588	2.25753966651863	0.0381737592180297	0.205792440560471
GO:0015278	intracellularly gated calcium channel activity	6/2914	17/18639	0.352941176470588	2.25753966651863	0.0381737592180297	0.205792440560471
GO:0051787	misfolded protein binding	6/2914	17/18639	0.352941176470588	2.25753966651863	0.0381737592180297	0.205792440560471
GO:0003725	double-stranded RNA binding	18/2914	75/18639	0.24	1.53512697323267	0.038236359802021	0.205792440560471
GO:0072341	modified amino acid binding	21/2914	91/18639	0.230769230769231	1.47608362810834	0.0396805117307467	0.212700394864408
GO:0005172	vascular endothelial growth factor receptor binding	5/2914	13/18639	0.384615384615385	2.46013938018056	0.0400470315228069	0.212940842314041
GO:0019855	calcium channel inhibitor activity	5/2914	13/18639	0.384615384615385	2.46013938018056	0.0400470315228069	0.212940842314041
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	20/2914	86/18639	0.232558139534884	1.48752613685336	0.0408375444213762	0.216275635255608
GO:0061135	endopeptidase regulator activity	38/2914	184/18639	0.206521739130435	1.32098788457521	0.041020492840927	0.216379014029431
GO:0008514	organic anion transmembrane transporter activity	53/2914	269/18639	0.197026022304833	1.26024983862038	0.0417057553074637	0.219120714393182
GO:0015101	organic cation transmembrane transporter activity	19/2914	81/18639	0.234567901234568	1.50038130099901	0.0419622846571905	0.219597094411543
GO:0098631	cell adhesion mediator activity	18/2914	76/18639	0.236842105263158	1.51492793411119	0.0430365890392526	0.224332456251852
GO:0015291	secondary active transmembrane transporter activity	56/2914	287/18639	0.195121951219512	1.24807070994526	0.0437578583184578	0.227197664367208
GO:0008093	cytoskeletal anchor activity	7/2914	22/18639	0.318181818181818	2.03520621451301	0.0448143318348336	0.230872277623812
GO:0030021	extracellular matrix structural constituent conferring compression resistance	7/2914	22/18639	0.318181818181818	2.03520621451301	0.0448143318348336	0.230872277623812
GO:0001727	lipid kinase activity	11/2914	41/18639	0.268292682926829	1.71609722617473	0.0460190399194986	0.236159724238047
GO:0005048	signal sequence binding	13/2914	51/18639	0.254901960784314	1.6304453147079	0.0465591750438667	0.23800906470301
GO:0051219	phosphoprotein binding	21/2914	93/18639	0.225806451612903	1.44433989417052	0.0488820243142054	0.248121317703993
GO:0016887	ATP hydrolysis activity	78/2914	417/18639	0.18705035971223	1.19644188561299	0.0490824368312433	0.248121317703993
GO:0023026	MHC class II protein complex binding	8/2914	27/18639	0.296296296296296	1.89521848547243	0.0490995356785847	0.248121317703993
GO:0098641	cadherin binding involved in cell-cell adhesion	6/2914	18/18639	0.333333333333333	2.13212079615649	0.0499085228975013	0.251250510708334
GO:0035401	histone H3Y41 kinase activity	25/2914	115/18639	0.217391304347826	1.39051356271075	0.050959320669279	0.254604304023115
GO:0140801	histone H2AXY142 kinase activity	25/2914	115/18639	0.217391304347826	1.39051356271075	0.050959320669279	0.254604304023115
GO:0042805	actinin binding	10/2914	37/18639	0.27027027027027	1.72874659147823	0.0532167633070679	0.264693192991368
GO:0051082	unfolded protein binding	26/2914	121/18639	0.214876033057851	1.37442497603476	0.0534524834241271	0.264693192991368
GO:0051879	Hsp90 protein binding	11/2914	42/18639	0.261904761904762	1.67523776840867	0.0538643246718881	0.264693192991368
GO:0005161	platelet-derived growth factor receptor binding	5/2914	14/18639	0.357142857142857	2.28441513873909	0.0544943890107085	0.264693192991368
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	5/2914	14/18639	0.357142857142857	2.28441513873909	0.0544943890107085	0.264693192991368
GO:0043021	ribonucleoprotein complex binding	36/2914	177/18639	0.203389830508475	1.30095506206158	0.0553798048505811	0.264693192991368
GO:0016849	phosphorus-oxygen lyase activity	7/2914	23/18639	0.304347826086957	1.94671898779505	0.0560195879771486	0.264693192991368
GO:0005345	purine nucleobase transmembrane transporter activity	4/2914	10/18639	0.4	2.55854495538778	0.0569770090653625	0.264693192991368
GO:0008239	dipeptidyl-peptidase activity	4/2914	10/18639	0.4	2.55854495538778	0.0569770090653625	0.264693192991368
GO:0015658	branched-chain amino acid transmembrane transporter activity	4/2914	10/18639	0.4	2.55854495538778	0.0569770090653625	0.264693192991368
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	4/2914	10/18639	0.4	2.55854495538778	0.0569770090653625	0.264693192991368
GO:0016868	intramolecular phosphotransferase activity	4/2914	10/18639	0.4	2.55854495538778	0.0569770090653625	0.264693192991368
GO:0030957	Tat protein binding	4/2914	10/18639	0.4	2.55854495538778	0.0569770090653625	0.264693192991368
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	4/2914	10/18639	0.4	2.55854495538778	0.0569770090653625	0.264693192991368
GO:0031434	mitogen-activated protein kinase kinase binding	4/2914	10/18639	0.4	2.55854495538778	0.0569770090653625	0.264693192991368
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	4/2914	10/18639	0.4	2.55854495538778	0.0569770090653625	0.264693192991368
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	4/2914	10/18639	0.4	2.55854495538778	0.0569770090653625	0.264693192991368
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	4/2914	10/18639	0.4	2.55854495538778	0.0569770090653625	0.264693192991368
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	4/2914	10/18639	0.4	2.55854495538778	0.0569770090653625	0.264693192991368
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	4/2914	10/18639	0.4	2.55854495538778	0.0569770090653625	0.264693192991368
GO:0051393	alpha-actinin binding	8/2914	28/18639	0.285714285714286	1.82753211099127	0.0596606485292992	0.276191254030742
GO:0019207	kinase regulator activity	55/2914	287/18639	0.191637630662021	1.22578373298195	0.0601497675647665	0.277485338870212
GO:0032266	phosphatidylinositol-3-phosphate binding	12/2914	48/18639	0.25	1.59909059711736	0.0620570451973668	0.285290027226783
GO:0043395	heparan sulfate proteoglycan binding	6/2914	19/18639	0.315789473684211	2.01990391214825	0.063619222358076	0.291459689972639
GO:0001091	RNA polymerase II general transcription initiation factor binding	7/2914	24/18639	0.291666666666667	1.86560569663693	0.0688123073362431	0.313921166743299
GO:0019003	GDP binding	17/2914	75/18639	0.226666666666667	1.44984214138641	0.0689962685213745	0.313921166743299
GO:0019887	protein kinase regulator activity	49/2914	255/18639	0.192156862745098	1.22910492954903	0.0697368423440899	0.316204038573887
GO:0060590	ATPase regulator activity	12/2914	49/18639	0.244897959183673	1.56645609513538	0.0709737585094269	0.317944763324232
GO:0035250	UDP-galactosyltransferase activity	8/2914	29/18639	0.275862068965517	1.7645137623364	0.0715433900850438	0.317944763324232
GO:0051861	glycolipid binding	8/2914	29/18639	0.275862068965517	1.7645137623364	0.0715433900850438	0.317944763324232
GO:0120283	protein serine/threonine kinase binding	5/2914	15/18639	0.333333333333333	2.13212079615649	0.071561585702886	0.317944763324232
GO:0141050	histone H3K deacetylase activity	5/2914	15/18639	0.333333333333333	2.13212079615649	0.071561585702886	0.317944763324232
GO:0141051	histone H4K deacetylase activity	5/2914	15/18639	0.333333333333333	2.13212079615649	0.071561585702886	0.317944763324232
GO:0003713	transcription coactivator activity	49/2914	256/18639	0.19140625	1.22430373841798	0.0736227366810087	0.326008372460386
GO:0017022	myosin binding	17/2914	76/18639	0.223684210526316	1.43076527110501	0.0764761761687657	0.331294752797458
GO:0140597	protein carrier chaperone	37/2914	188/18639	0.196808510638298	1.2588585551775	0.0786675499354977	0.331294752797458
GO:0000099	sulfur amino acid transmembrane transporter activity	4/2914	11/18639	0.363636363636364	2.32594995944344	0.0787758016593111	0.331294752797458
GO:0002162	dystroglycan binding	4/2914	11/18639	0.363636363636364	2.32594995944344	0.0787758016593111	0.331294752797458
GO:0004016	adenylate cyclase activity	4/2914	11/18639	0.363636363636364	2.32594995944344	0.0787758016593111	0.331294752797458
GO:0005225	volume-sensitive anion channel activity	4/2914	11/18639	0.363636363636364	2.32594995944344	0.0787758016593111	0.331294752797458
GO:0008526	phosphatidylinositol transfer activity	4/2914	11/18639	0.363636363636364	2.32594995944344	0.0787758016593111	0.331294752797458
GO:0015205	nucleobase transmembrane transporter activity	4/2914	11/18639	0.363636363636364	2.32594995944344	0.0787758016593111	0.331294752797458
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	4/2914	11/18639	0.363636363636364	2.32594995944344	0.0787758016593111	0.331294752797458
GO:0035252	UDP-xylosyltransferase activity	4/2914	11/18639	0.363636363636364	2.32594995944344	0.0787758016593111	0.331294752797458
GO:0042285	xylosyltransferase activity	4/2914	11/18639	0.363636363636364	2.32594995944344	0.0787758016593111	0.331294752797458
GO:0043522	leucine zipper domain binding	4/2914	11/18639	0.363636363636364	2.32594995944344	0.0787758016593111	0.331294752797458
GO:0047676	arachidonate-CoA ligase activity	4/2914	11/18639	0.363636363636364	2.32594995944344	0.0787758016593111	0.331294752797458
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	4/2914	11/18639	0.363636363636364	2.32594995944344	0.0787758016593111	0.331294752797458
GO:0180030	inositol phosphate kinase activity	4/2914	11/18639	0.363636363636364	2.32594995944344	0.0787758016593111	0.331294752797458
GO:0016505	peptidase activator activity involved in apoptotic process	6/2914	20/18639	0.3	1.91890871654084	0.0793205714779413	0.331294752797458
GO:0030742	GTP-dependent protein binding	6/2914	20/18639	0.3	1.91890871654084	0.0793205714779413	0.331294752797458
GO:0061608	nuclear import signal receptor activity	6/2914	20/18639	0.3	1.91890871654084	0.0793205714779413	0.331294752797458
GO:0017124	SH3 domain binding	24/2914	115/18639	0.208695652173913	1.33489302020232	0.0811479858047971	0.33786142517469
GO:0140303	intramembrane lipid transporter activity	11/2914	45/18639	0.244444444444444	1.56355525051476	0.0825441793482332	0.342597158172604
GO:0017025	TBP-class protein binding	7/2914	25/18639	0.28	1.79098146877145	0.0832055769713159	0.343190604081066
GO:0047617	fatty acyl-CoA hydrolase activity	7/2914	25/18639	0.28	1.79098146877145	0.0832055769713159	0.343190604081066
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	8/2914	30/18639	0.266666666666667	1.70569663692519	0.084761089826998	0.347828627672543
GO:0061631	ubiquitin conjugating enzyme activity	9/2914	35/18639	0.257142857142857	1.64477889989215	0.0848554733672442	0.347828627672543
GO:0015026	coreceptor activity	14/2914	61/18639	0.229508196721311	1.46801759735365	0.0853617313697343	0.348823865226939
GO:0005024	transforming growth factor beta receptor activity	5/2914	16/18639	0.3125	1.99886324639671	0.0911998088180431	0.367016859802702
GO:0005159	insulin-like growth factor receptor binding	5/2914	16/18639	0.3125	1.99886324639671	0.0911998088180431	0.367016859802702
GO:0030275	LRR domain binding	5/2914	16/18639	0.3125	1.99886324639671	0.0911998088180431	0.367016859802702
GO:0055102	lipase inhibitor activity	5/2914	16/18639	0.3125	1.99886324639671	0.0911998088180431	0.367016859802702
GO:0140328	floppase activity	5/2914	16/18639	0.3125	1.99886324639671	0.0911998088180431	0.367016859802702
GO:0019199	transmembrane receptor protein kinase activity	17/2914	78/18639	0.217948717948718	1.39407898210232	0.0929900473233499	0.373087341382167
GO:0019208	phosphatase regulator activity	24/2914	117/18639	0.205128205128205	1.3120743360963	0.0947915823912423	0.379166329564969
GO:0042169	SH2 domain binding	10/2914	41/18639	0.24390243902439	1.56008838743157	0.0962623614845604	0.381590917980713
GO:0061650	ubiquitin-like protein conjugating enzyme activity	10/2914	41/18639	0.24390243902439	1.56008838743157	0.0962623614845604	0.381590917980713
GO:0140318	protein transporter activity	10/2914	41/18639	0.24390243902439	1.56008838743157	0.0962623614845604	0.381590917980713
GO:0004033	aldo-keto reductase (NADPH) activity	9/2914	36/18639	0.25	1.59909059711736	0.0981749629064838	0.385557671157739
GO:0016289	acyl-CoA hydrolase activity	7/2914	26/18639	0.269230769230769	1.72209756612639	0.0991864096042297	0.385557671157739
GO:0050681	nuclear androgen receptor binding	7/2914	26/18639	0.269230769230769	1.72209756612639	0.0991864096042297	0.385557671157739
GO:0052742	phosphatidylinositol kinase activity	7/2914	26/18639	0.269230769230769	1.72209756612639	0.0991864096042297	0.385557671157739
GO:0070006	metalloaminopeptidase activity	7/2914	26/18639	0.269230769230769	1.72209756612639	0.0991864096042297	0.385557671157739
GO:0070412	R-SMAD binding	7/2914	26/18639	0.269230769230769	1.72209756612639	0.0991864096042297	0.385557671157739
GO:0043022	ribosome binding	23/2914	112/18639	0.205357142857143	1.31353870477498	0.0993014847921367	0.385557671157739
GO:1990841	promoter-specific chromatin binding	15/2914	68/18639	0.220588235294118	1.41096229157415	0.101222497161855	0.387035000355546
GO:0140658	ATP-dependent chromatin remodeler activity	31/2914	158/18639	0.19620253164557	1.25498249394021	0.103360601187056	0.387035000355546
GO:0019888	protein phosphatase regulator activity	22/2914	107/18639	0.205607476635514	1.31513993033951	0.104061591556986	0.387035000355546
GO:0004032	aldose reductase (NADPH) activity	4/2914	12/18639	0.333333333333333	2.13212079615649	0.104066812784422	0.387035000355546
GO:0004526	ribonuclease P activity	4/2914	12/18639	0.333333333333333	2.13212079615649	0.104066812784422	0.387035000355546
GO:0004859	phospholipase inhibitor activity	4/2914	12/18639	0.333333333333333	2.13212079615649	0.104066812784422	0.387035000355546
GO:0005025	transforming growth factor beta receptor activity, type I	4/2914	12/18639	0.333333333333333	2.13212079615649	0.104066812784422	0.387035000355546
GO:0005026	transforming growth factor beta receptor activity, type II	4/2914	12/18639	0.333333333333333	2.13212079615649	0.104066812784422	0.387035000355546
GO:0005165	neurotrophin receptor binding	4/2914	12/18639	0.333333333333333	2.13212079615649	0.104066812784422	0.387035000355546
GO:0010853	cyclase activator activity	4/2914	12/18639	0.333333333333333	2.13212079615649	0.104066812784422	0.387035000355546
GO:0015368	calcium:monoatomic cation antiporter activity	4/2914	12/18639	0.333333333333333	2.13212079615649	0.104066812784422	0.387035000355546
GO:0016361	activin receptor activity, type I	4/2914	12/18639	0.333333333333333	2.13212079615649	0.104066812784422	0.387035000355546
GO:0016362	activin receptor activity, type II	4/2914	12/18639	0.333333333333333	2.13212079615649	0.104066812784422	0.387035000355546
GO:0017002	activin receptor activity	4/2914	12/18639	0.333333333333333	2.13212079615649	0.104066812784422	0.387035000355546
GO:0042301	phosphate ion binding	4/2914	12/18639	0.333333333333333	2.13212079615649	0.104066812784422	0.387035000355546
GO:0001784	phosphotyrosine residue binding	11/2914	47/18639	0.234042553191489	1.49702098453541	0.106074102521879	0.392296401505496
GO:0140359	ABC-type transporter activity	11/2914	47/18639	0.234042553191489	1.49702098453541	0.106074102521879	0.392296401505496
GO:0008307	structural constituent of muscle	10/2914	42/18639	0.238095238095238	1.52294342582606	0.10951174798852	0.403881766954878
GO:0002039	p53 binding	15/2914	69/18639	0.217391304347826	1.39051356271075	0.111557209423508	0.407612094848994
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	5/2914	17/18639	0.294117647058824	1.88128305543219	0.113293996151382	0.407612094848994
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	5/2914	17/18639	0.294117647058824	1.88128305543219	0.113293996151382	0.407612094848994
GO:0017110	nucleoside diphosphate phosphatase activity	5/2914	17/18639	0.294117647058824	1.88128305543219	0.113293996151382	0.407612094848994
GO:0019198	transmembrane receptor protein phosphatase activity	5/2914	17/18639	0.294117647058824	1.88128305543219	0.113293996151382	0.407612094848994
GO:0030169	low-density lipoprotein particle binding	5/2914	17/18639	0.294117647058824	1.88128305543219	0.113293996151382	0.407612094848994
GO:0031489	myosin V binding	5/2914	17/18639	0.294117647058824	1.88128305543219	0.113293996151382	0.407612094848994
GO:1901567	fatty acid derivative binding	5/2914	17/18639	0.294117647058824	1.88128305543219	0.113293996151382	0.407612094848994
GO:1990226	histone methyltransferase binding	5/2914	17/18639	0.294117647058824	1.88128305543219	0.113293996151382	0.407612094848994
GO:0008378	galactosyltransferase activity	8/2914	32/18639	0.25	1.59909059711736	0.115166043743158	0.410992190673256
GO:0051059	NF-kappaB binding	8/2914	32/18639	0.25	1.59909059711736	0.115166043743158	0.410992190673256
GO:0120015	sterol transfer activity	8/2914	32/18639	0.25	1.59909059711736	0.115166043743158	0.410992190673256
GO:0050660	flavin adenine dinucleotide binding	18/2914	86/18639	0.209302325581395	1.33877352316803	0.116032691186285	0.410992190673256
GO:0001671	ATPase activator activity	7/2914	27/18639	0.259259259259259	1.65831617478838	0.116716815478206	0.410992190673256
GO:0008320	protein transmembrane transporter activity	7/2914	27/18639	0.259259259259259	1.65831617478838	0.116716815478206	0.410992190673256
GO:0015252	proton channel activity	7/2914	27/18639	0.259259259259259	1.65831617478838	0.116716815478206	0.410992190673256
GO:0016405	CoA-ligase activity	7/2914	27/18639	0.259259259259259	1.65831617478838	0.116716815478206	0.410992190673256
GO:0008201	heparin binding	33/2914	172/18639	0.191860465116279	1.22720906290402	0.119894910476329	0.421063293025622
GO:0015631	tubulin binding	69/2914	385/18639	0.179220779220779	1.14636105143998	0.12039044725686	0.421685058645722
GO:0004879	nuclear receptor activity	13/2914	59/18639	0.220338983050847	1.40936798390005	0.121934117519769	0.425965096559826
GO:0008375	acetylglucosaminyltransferase activity	10/2914	43/18639	0.232558139534884	1.48752613685336	0.123741397510159	0.430009475862075
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	10/2914	43/18639	0.232558139534884	1.48752613685336	0.123741397510159	0.430009475862075
GO:0003925	G protein activity	12/2914	54/18639	0.222222222222222	1.42141386410432	0.127431011115718	0.441642309952277
GO:0038024	cargo receptor activity	14/2914	65/18639	0.215384615384615	1.37767805290111	0.128380111267817	0.441642309952277
GO:0160215	deacylase activity	14/2914	65/18639	0.215384615384615	1.37767805290111	0.128380111267817	0.441642309952277
GO:0019842	vitamin binding	29/2914	150/18639	0.193333333333333	1.23663006177076	0.128423179253494	0.441642309952277
GO:0004222	metalloendopeptidase activity	22/2914	110/18639	0.2	1.27927247769389	0.129914868684223	0.444193784163343
GO:0140311	protein sequestering activity	8/2914	33/18639	0.242424242424242	1.55063330629563	0.13229281703332	0.444193784163343
GO:0017154	semaphorin receptor activity	4/2914	13/18639	0.307692307692308	1.96811150414445	0.132520048900695	0.444193784163343
GO:0019104	DNA N-glycosylase activity	4/2914	13/18639	0.307692307692308	1.96811150414445	0.132520048900695	0.444193784163343
GO:0030955	potassium ion binding	4/2914	13/18639	0.307692307692308	1.96811150414445	0.132520048900695	0.444193784163343
GO:0031994	insulin-like growth factor I binding	4/2914	13/18639	0.307692307692308	1.96811150414445	0.132520048900695	0.444193784163343
GO:0045159	myosin II binding	4/2914	13/18639	0.307692307692308	1.96811150414445	0.132520048900695	0.444193784163343
GO:0061459	L-arginine transmembrane transporter activity	4/2914	13/18639	0.307692307692308	1.96811150414445	0.132520048900695	0.444193784163343
GO:0070123	transforming growth factor beta receptor activity, type III	4/2914	13/18639	0.307692307692308	1.96811150414445	0.132520048900695	0.444193784163343
GO:0071714	icosanoid transmembrane transporter activity	4/2914	13/18639	0.307692307692308	1.96811150414445	0.132520048900695	0.444193784163343
GO:0098531	ligand-modulated transcription factor activity	13/2914	60/18639	0.216666666666667	1.38587851750172	0.134568288737885	0.445361655370067
GO:0019789	SUMO transferase activity	7/2914	28/18639	0.25	1.59909059711736	0.135735537794508	0.445361655370067
GO:0051019	mitogen-activated protein kinase binding	7/2914	28/18639	0.25	1.59909059711736	0.135735537794508	0.445361655370067
GO:0000510	H3-H4 histone complex chaperone activity	29/2914	151/18639	0.19205298013245	1.22844045871268	0.136332914323443	0.445361655370067
GO:0140584	chromatin extrusion motor activity	29/2914	151/18639	0.19205298013245	1.22844045871268	0.136332914323443	0.445361655370067
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	29/2914	151/18639	0.19205298013245	1.22844045871268	0.136332914323443	0.445361655370067
GO:0140849	ATP-dependent H2AZ histone chaperone activity	29/2914	151/18639	0.19205298013245	1.22844045871268	0.136332914323443	0.445361655370067
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	5/2914	18/18639	0.277777777777778	1.7767673301304	0.137673024325952	0.445361655370067
GO:0017128	phospholipid scramblase activity	5/2914	18/18639	0.277777777777778	1.7767673301304	0.137673024325952	0.445361655370067
GO:0070064	proline-rich region binding	5/2914	18/18639	0.277777777777778	1.7767673301304	0.137673024325952	0.445361655370067
GO:1901611	phosphatidylglycerol binding	5/2914	18/18639	0.277777777777778	1.7767673301304	0.137673024325952	0.445361655370067
GO:0017134	fibroblast growth factor binding	6/2914	23/18639	0.260869565217391	1.6686162752529	0.137914107780761	0.445361655370067
GO:0070577	lysine-acetylated histone binding	6/2914	23/18639	0.260869565217391	1.6686162752529	0.137914107780761	0.445361655370067
GO:0099186	structural constituent of postsynapse	6/2914	23/18639	0.260869565217391	1.6686162752529	0.137914107780761	0.445361655370067
GO:0140103	catalytic activity, acting on a glycoprotein	6/2914	23/18639	0.260869565217391	1.6686162752529	0.137914107780761	0.445361655370067
GO:0001223	transcription coactivator binding	10/2914	44/18639	0.227272727272727	1.45371872465215	0.138927366334294	0.447542172814125
GO:0030165	PDZ domain binding	17/2914	83/18639	0.204819277108434	1.31009832052989	0.143447019645935	0.460980228182567
GO:0015616	DNA translocase activity	29/2914	152/18639	0.190789473684211	1.22035861358957	0.144527970769971	0.462005627920771
GO:0140674	ATP-dependent histone chaperone activity	29/2914	152/18639	0.190789473684211	1.22035861358957	0.144527970769971	0.462005627920771
GO:0016776	phosphotransferase activity, phosphate group as acceptor	9/2914	39/18639	0.230769230769231	1.47608362810834	0.144812942286344	0.462005627920771
GO:0008013	beta-catenin binding	21/2914	106/18639	0.19811320754717	1.26720386941376	0.146415274618416	0.465994768256691
GO:0140713	histone chaperone activity	31/2914	164/18639	0.189024390243902	1.20906850025947	0.147248733545361	0.467523556868243
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	8/2914	34/18639	0.235294117647059	1.50502644434575	0.150635496486666	0.47669918587688
GO:0004867	serine-type endopeptidase inhibitor activity	19/2914	95/18639	0.2	1.27927247769389	0.150858730273726	0.47669918587688
GO:0015085	calcium ion transmembrane transporter activity	28/2914	147/18639	0.19047619047619	1.21835474066085	0.151569238852254	0.477803981524723
GO:0061775	cohesin loader activity	29/2914	153/18639	0.189542483660131	1.21238241350075	0.153005858956075	0.481187071871361
GO:0016500	protein-hormone receptor activity	14/2914	67/18639	0.208955223880597	1.33655333490407	0.153778282335295	0.482470250739171
GO:0004715	non-membrane spanning protein tyrosine kinase activity	10/2914	45/18639	0.222222222222222	1.42141386410432	0.155036848330311	0.485269000447594
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	7/2914	29/18639	0.241379310344828	1.54394954204435	0.156160312065701	0.485343317312178
GO:0097472	cyclin-dependent protein kinase activity	7/2914	29/18639	0.241379310344828	1.54394954204435	0.156160312065701	0.485343317312178
GO:0099604	ligand-gated calcium channel activity	7/2914	29/18639	0.241379310344828	1.54394954204435	0.156160312065701	0.485343317312178
GO:0030552	cAMP binding	6/2914	24/18639	0.25	1.59909059711736	0.160948041262267	0.48940530050405
GO:0140033	acetylation-dependent protein binding	6/2914	24/18639	0.25	1.59909059711736	0.160948041262267	0.48940530050405
GO:0004177	aminopeptidase activity	9/2914	40/18639	0.225	1.43918153740563	0.162466021166528	0.48940530050405
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	9/2914	40/18639	0.225	1.43918153740563	0.162466021166528	0.48940530050405
GO:0030331	nuclear estrogen receptor binding	9/2914	40/18639	0.225	1.43918153740563	0.162466021166528	0.48940530050405
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	9/2914	40/18639	0.225	1.43918153740563	0.162466021166528	0.48940530050405
GO:0003689	DNA clamp loader activity	30/2914	160/18639	0.1875	1.19931794783802	0.162937866244105	0.48940530050405
GO:0005021	vascular endothelial growth factor receptor activity	11/2914	51/18639	0.215686274509804	1.37960757398361	0.163496406410368	0.48940530050405
GO:0030544	Hsp70 protein binding	11/2914	51/18639	0.215686274509804	1.37960757398361	0.163496406410368	0.48940530050405
GO:0004065	arylsulfatase activity	4/2914	14/18639	0.285714285714286	1.82753211099127	0.16373031285669	0.48940530050405
GO:0008191	metalloendopeptidase inhibitor activity	4/2914	14/18639	0.285714285714286	1.82753211099127	0.16373031285669	0.48940530050405
GO:0008559	ABC-type xenobiotic transporter activity	4/2914	14/18639	0.285714285714286	1.82753211099127	0.16373031285669	0.48940530050405
GO:0042043	neurexin family protein binding	4/2914	14/18639	0.285714285714286	1.82753211099127	0.16373031285669	0.48940530050405
GO:0098821	BMP receptor activity	4/2914	14/18639	0.285714285714286	1.82753211099127	0.16373031285669	0.48940530050405
GO:0005520	insulin-like growth factor binding	5/2914	19/18639	0.263157894736842	1.68325326012354	0.16412081074305	0.48940530050405
GO:0016918	retinal binding	5/2914	19/18639	0.263157894736842	1.68325326012354	0.16412081074305	0.48940530050405
GO:0031420	alkali metal ion binding	5/2914	19/18639	0.263157894736842	1.68325326012354	0.16412081074305	0.48940530050405
GO:0140036	ubiquitin-modified protein reader activity	5/2914	19/18639	0.263157894736842	1.68325326012354	0.16412081074305	0.48940530050405
GO:0008237	metallopeptidase activity	34/2914	184/18639	0.184782608695652	1.18193652830414	0.166556253581789	0.49555163987031
GO:0030145	manganese ion binding	14/2914	68/18639	0.205882352941176	1.31689813880254	0.167403856269149	0.496956739238461
GO:0140030	modification-dependent protein binding	32/2914	173/18639	0.184971098265896	1.18314217590186	0.173572951755526	0.514117646810551
GO:0031624	ubiquitin conjugating enzyme binding	7/2914	30/18639	0.233333333333333	1.49248455730954	0.177890510138349	0.524559098938028
GO:0098918	structural constituent of synapse	7/2914	30/18639	0.233333333333333	1.49248455730954	0.177890510138349	0.524559098938028
GO:0140097	catalytic activity, acting on DNA	59/2914	336/18639	0.175595238095238	1.12317077654672	0.181868223649394	0.526520134796807
GO:0043178	alcohol binding	18/2914	92/18639	0.195652173913043	1.25146220643968	0.182932201082512	0.526520134796807
GO:0052689	carboxylic ester hydrolase activity	18/2914	92/18639	0.195652173913043	1.25146220643968	0.182932201082512	0.526520134796807
GO:0004519	endonuclease activity	24/2914	127/18639	0.188976377952756	1.2087613962462	0.184102246045041	0.526520134796807
GO:0042826	histone deacetylase binding	24/2914	127/18639	0.188976377952756	1.2087613962462	0.184102246045041	0.526520134796807
GO:0008483	transaminase activity	6/2914	25/18639	0.24	1.53512697323267	0.18549829314362	0.526520134796807
GO:0015645	fatty acid ligase activity	6/2914	25/18639	0.24	1.53512697323267	0.18549829314362	0.526520134796807
GO:0120020	cholesterol transfer activity	6/2914	25/18639	0.24	1.53512697323267	0.18549829314362	0.526520134796807
GO:0120515	fatty acid-CoA ligase activity	6/2914	25/18639	0.24	1.53512697323267	0.18549829314362	0.526520134796807
GO:0044183	protein folding chaperone	15/2914	75/18639	0.2	1.27927247769389	0.185958554318212	0.526520134796807
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	5/2914	20/18639	0.25	1.59909059711736	0.192387557164753	0.526520134796807
GO:0005326	neurotransmitter transmembrane transporter activity	5/2914	20/18639	0.25	1.59909059711736	0.192387557164753	0.526520134796807
GO:0015095	magnesium ion transmembrane transporter activity	5/2914	20/18639	0.25	1.59909059711736	0.192387557164753	0.526520134796807
GO:0016004	phospholipase activator activity	5/2914	20/18639	0.25	1.59909059711736	0.192387557164753	0.526520134796807
GO:0008081	phosphoric diester hydrolase activity	17/2914	87/18639	0.195402298850575	1.24986391498828	0.192896556011254	0.526520134796807
GO:0033218	amide binding	44/2914	247/18639	0.178137651821862	1.13943297608363	0.193033558297321	0.526520134796807
GO:0097110	scaffold protein binding	14/2914	70/18639	0.2	1.27927247769389	0.196399576383859	0.526520134796807
GO:0000182	rDNA binding	3/2914	10/18639	0.3	1.91890871654084	0.196478797877684	0.526520134796807
GO:0004090	carbonyl reductase (NADPH) activity	3/2914	10/18639	0.3	1.91890871654084	0.196478797877684	0.526520134796807
GO:0004382	GDP phosphatase activity	3/2914	10/18639	0.3	1.91890871654084	0.196478797877684	0.526520134796807
GO:0004862	cAMP-dependent protein kinase inhibitor activity	3/2914	10/18639	0.3	1.91890871654084	0.196478797877684	0.526520134796807
GO:0005337	nucleoside transmembrane transporter activity	3/2914	10/18639	0.3	1.91890871654084	0.196478797877684	0.526520134796807
GO:0015203	polyamine transmembrane transporter activity	3/2914	10/18639	0.3	1.91890871654084	0.196478797877684	0.526520134796807
GO:0015924	mannosyl-oligosaccharide mannosidase activity	3/2914	10/18639	0.3	1.91890871654084	0.196478797877684	0.526520134796807
GO:0016427	tRNA (cytidine) methyltransferase activity	3/2914	10/18639	0.3	1.91890871654084	0.196478797877684	0.526520134796807
GO:0031956	medium-chain fatty acid-CoA ligase activity	3/2914	10/18639	0.3	1.91890871654084	0.196478797877684	0.526520134796807
GO:0031996	thioesterase binding	3/2914	10/18639	0.3	1.91890871654084	0.196478797877684	0.526520134796807
GO:0033204	ribonuclease P RNA binding	3/2914	10/18639	0.3	1.91890871654084	0.196478797877684	0.526520134796807
GO:0035374	chondroitin sulfate binding	3/2914	10/18639	0.3	1.91890871654084	0.196478797877684	0.526520134796807
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	3/2914	10/18639	0.3	1.91890871654084	0.196478797877684	0.526520134796807
GO:0043121	neurotrophin binding	3/2914	10/18639	0.3	1.91890871654084	0.196478797877684	0.526520134796807
GO:0043295	glutathione binding	3/2914	10/18639	0.3	1.91890871654084	0.196478797877684	0.526520134796807
GO:0043422	protein kinase B binding	3/2914	10/18639	0.3	1.91890871654084	0.196478797877684	0.526520134796807
GO:0047429	nucleoside triphosphate diphosphatase activity	3/2914	10/18639	0.3	1.91890871654084	0.196478797877684	0.526520134796807
GO:0050815	phosphoserine residue binding	3/2914	10/18639	0.3	1.91890871654084	0.196478797877684	0.526520134796807
GO:0070739	protein-glutamic acid ligase activity	3/2914	10/18639	0.3	1.91890871654084	0.196478797877684	0.526520134796807
GO:0070740	tubulin-glutamic acid ligase activity	3/2914	10/18639	0.3	1.91890871654084	0.196478797877684	0.526520134796807
GO:0140999	histone H3K4 trimethyltransferase activity	3/2914	10/18639	0.3	1.91890871654084	0.196478797877684	0.526520134796807
GO:0008146	sulfotransferase activity	11/2914	53/18639	0.207547169811321	1.32754691081442	0.196974868111163	0.526520134796807
GO:0004467	long-chain fatty acid-CoA ligase activity	4/2914	15/18639	0.266666666666667	1.70569663692519	0.197246213639892	0.526520134796807
GO:0004559	alpha-mannosidase activity	4/2914	15/18639	0.266666666666667	1.70569663692519	0.197246213639892	0.526520134796807
GO:0005041	low-density lipoprotein particle receptor activity	4/2914	15/18639	0.266666666666667	1.70569663692519	0.197246213639892	0.526520134796807
GO:0005402	carbohydrate:monoatomic cation symporter activity	4/2914	15/18639	0.266666666666667	1.70569663692519	0.197246213639892	0.526520134796807
GO:0008242	omega peptidase activity	4/2914	15/18639	0.266666666666667	1.70569663692519	0.197246213639892	0.526520134796807
GO:0031386	protein tag activity	4/2914	15/18639	0.266666666666667	1.70569663692519	0.197246213639892	0.526520134796807
GO:0140776	protein-containing complex destabilizing activity	4/2914	15/18639	0.266666666666667	1.70569663692519	0.197246213639892	0.526520134796807
GO:0141047	molecular tag activity	4/2914	15/18639	0.266666666666667	1.70569663692519	0.197246213639892	0.526520134796807
GO:0016878	acid-thiol ligase activity	7/2914	31/18639	0.225806451612903	1.44433989417052	0.200810036317666	0.533880498161828
GO:0017147	Wnt-protein binding	7/2914	31/18639	0.225806451612903	1.44433989417052	0.200810036317666	0.533880498161828
GO:0043177	organic acid binding	34/2914	189/18639	0.17989417989418	1.15066836617969	0.210689279192617	0.55642707805964
GO:0005112	Notch binding	6/2914	26/18639	0.230769230769231	1.47608362810834	0.211391858205437	0.55642707805964
GO:0034237	protein kinase A regulatory subunit binding	6/2914	26/18639	0.230769230769231	1.47608362810834	0.211391858205437	0.55642707805964
GO:0050750	low-density lipoprotein particle receptor binding	6/2914	26/18639	0.230769230769231	1.47608362810834	0.211391858205437	0.55642707805964
GO:0120014	phospholipid transfer activity	6/2914	26/18639	0.230769230769231	1.47608362810834	0.211391858205437	0.55642707805964
GO:0023023	MHC protein complex binding	8/2914	37/18639	0.216216216216216	1.38299727318259	0.212216370314665	0.557489036302811
GO:0050661	NADP binding	11/2914	54/18639	0.203703703703704	1.3029627087623	0.214765157109998	0.563067461413142
GO:0004714	transmembrane receptor protein tyrosine kinase activity	12/2914	60/18639	0.2	1.27927247769389	0.219888126934656	0.574596751328837
GO:0005245	voltage-gated calcium channel activity	9/2914	43/18639	0.209302325581395	1.33877352316803	0.2209525080966	0.574596751328837
GO:0008200	ion channel inhibitor activity	9/2914	43/18639	0.209302325581395	1.33877352316803	0.2209525080966	0.574596751328837
GO:0008373	sialyltransferase activity	5/2914	21/18639	0.238095238095238	1.52294342582606	0.222200556405109	0.574596751328837
GO:0009931	calcium-dependent protein serine/threonine kinase activity	5/2914	21/18639	0.238095238095238	1.52294342582606	0.222200556405109	0.574596751328837
GO:0015174	basic amino acid transmembrane transporter activity	5/2914	21/18639	0.238095238095238	1.52294342582606	0.222200556405109	0.574596751328837
GO:0051010	microtubule plus-end binding	5/2914	21/18639	0.238095238095238	1.52294342582606	0.222200556405109	0.574596751328837
GO:0022884	macromolecule transmembrane transporter activity	7/2914	32/18639	0.21875	1.39920427247769	0.224790354238529	0.576787653123667
GO:0071813	lipoprotein particle binding	7/2914	32/18639	0.21875	1.39920427247769	0.224790354238529	0.576787653123667
GO:0071814	protein-lipid complex binding	7/2914	32/18639	0.21875	1.39920427247769	0.224790354238529	0.576787653123667
GO:0140142	nucleocytoplasmic carrier activity	7/2914	32/18639	0.21875	1.39920427247769	0.224790354238529	0.576787653123667
GO:0016763	pentosyltransferase activity	10/2914	49/18639	0.204081632653061	1.30538007927948	0.227778283503155	0.582463889736091
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	82/2914	484/18639	0.169421487603306	1.08368123110433	0.227882397948108	0.582463889736091
GO:0000062	fatty-acyl-CoA binding	4/2914	16/18639	0.25	1.59909059711736	0.232595015247174	0.587701908754311
GO:0015923	mannosidase activity	4/2914	16/18639	0.25	1.59909059711736	0.232595015247174	0.587701908754311
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	4/2914	16/18639	0.25	1.59909059711736	0.232595015247174	0.587701908754311
GO:0019841	retinol binding	4/2914	16/18639	0.25	1.59909059711736	0.232595015247174	0.587701908754311
GO:0034450	ubiquitin-ubiquitin ligase activity	4/2914	16/18639	0.25	1.59909059711736	0.232595015247174	0.587701908754311
GO:0097027	ubiquitin-protein transferase activator activity	4/2914	16/18639	0.25	1.59909059711736	0.232595015247174	0.587701908754311
GO:0042887	amide transmembrane transporter activity	8/2914	38/18639	0.210526315789474	1.34660260809883	0.234625048823783	0.591702027890836
GO:0008094	ATP-dependent activity, acting on DNA	37/2914	210/18639	0.176190476190476	1.12697813511129	0.238247340106879	0.593254126652655
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	6/2914	27/18639	0.222222222222222	1.42141386410432	0.238441870413217	0.593254126652655
GO:0004143	ATP-dependent diacylglycerol kinase activity	3/2914	11/18639	0.272727272727273	1.74446246958258	0.240617421459574	0.593254126652655
GO:0004523	RNA-DNA hybrid ribonuclease activity	3/2914	11/18639	0.272727272727273	1.74446246958258	0.240617421459574	0.593254126652655
GO:0008046	axon guidance receptor activity	3/2914	11/18639	0.272727272727273	1.74446246958258	0.240617421459574	0.593254126652655
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	3/2914	11/18639	0.272727272727273	1.74446246958258	0.240617421459574	0.593254126652655
GO:0032050	clathrin heavy chain binding	3/2914	11/18639	0.272727272727273	1.74446246958258	0.240617421459574	0.593254126652655
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	3/2914	11/18639	0.272727272727273	1.74446246958258	0.240617421459574	0.593254126652655
GO:0050998	nitric-oxide synthase binding	3/2914	11/18639	0.272727272727273	1.74446246958258	0.240617421459574	0.593254126652655
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	3/2914	11/18639	0.272727272727273	1.74446246958258	0.240617421459574	0.593254126652655
GO:0140537	transcription regulator activator activity	3/2914	11/18639	0.272727272727273	1.74446246958258	0.240617421459574	0.593254126652655
GO:1900750	oligopeptide binding	3/2914	11/18639	0.272727272727273	1.74446246958258	0.240617421459574	0.593254126652655
GO:0016248	channel inhibitor activity	9/2914	44/18639	0.204545454545455	1.30834685218693	0.242044687406907	0.594558749771327
GO:0019205	nucleobase-containing compound kinase activity	9/2914	44/18639	0.204545454545455	1.30834685218693	0.242044687406907	0.594558749771327
GO:0042393	histone binding	43/2914	247/18639	0.174089068825911	1.11353677208173	0.243371032391315	0.595625290731931
GO:0004521	RNA endonuclease activity	14/2914	73/18639	0.191780821917808	1.22669963614483	0.24382848004283	0.595625290731931
GO:0043539	protein serine/threonine kinase activator activity	14/2914	73/18639	0.191780821917808	1.22669963614483	0.24382848004283	0.595625290731931
GO:0008234	cysteine-type peptidase activity	33/2914	187/18639	0.176470588235294	1.12876983325932	0.250338545152605	0.608593433172726
GO:0030414	peptidase inhibitor activity	30/2914	169/18639	0.177514792899408	1.13544894469872	0.251850434574623	0.608593433172726
GO:0030170	pyridoxal phosphate binding	11/2914	56/18639	0.196428571428571	1.2564283263065	0.252188010216375	0.608593433172726
GO:0004407	histone deacetylase activity	5/2914	22/18639	0.227272727272727	1.45371872465215	0.253274155346051	0.608593433172726
GO:0033558	protein lysine deacetylase activity	5/2914	22/18639	0.227272727272727	1.45371872465215	0.253274155346051	0.608593433172726
GO:0034062	5'-3' RNA polymerase activity	5/2914	22/18639	0.227272727272727	1.45371872465215	0.253274155346051	0.608593433172726
GO:0097747	RNA polymerase activity	5/2914	22/18639	0.227272727272727	1.45371872465215	0.253274155346051	0.608593433172726
GO:0140035	ubiquitin-like protein reader activity	5/2914	22/18639	0.227272727272727	1.45371872465215	0.253274155346051	0.608593433172726
GO:0140517	protein-RNA adaptor activity	5/2914	22/18639	0.227272727272727	1.45371872465215	0.253274155346051	0.608593433172726
GO:0032934	sterol binding	13/2914	68/18639	0.191176470588235	1.22283398603093	0.258405661916016	0.619799087639139
GO:0016829	lyase activity	35/2914	200/18639	0.175	1.11936341798215	0.259203689015863	0.620588940790239
GO:0031491	nucleosome binding	14/2914	74/18639	0.189189189189189	1.21012261403476	0.260553680081845	0.622695076585492
GO:0046915	transition metal ion transmembrane transporter activity	9/2914	45/18639	0.2	1.27927247769389	0.263796647176056	0.625538947309808
GO:0051539	4 iron, 4 sulfur cluster binding	9/2914	45/18639	0.2	1.27927247769389	0.263796647176056	0.625538947309808
GO:0141110	transporter inhibitor activity	9/2914	45/18639	0.2	1.27927247769389	0.263796647176056	0.625538947309808
GO:0042626	ATPase-coupled transmembrane transporter activity	18/2914	98/18639	0.183673469387755	1.17484207135153	0.265192917136639	0.625538947309808
GO:0016866	intramolecular transferase activity	6/2914	28/18639	0.214285714285714	1.37064908324346	0.266452688400138	0.625538947309808
GO:0045499	chemorepellent activity	6/2914	28/18639	0.214285714285714	1.37064908324346	0.266452688400138	0.625538947309808
GO:0050698	proteoglycan sulfotransferase activity	6/2914	28/18639	0.214285714285714	1.37064908324346	0.266452688400138	0.625538947309808
GO:0051959	dynein light intermediate chain binding	6/2914	28/18639	0.214285714285714	1.37064908324346	0.266452688400138	0.625538947309808
GO:0005010	insulin-like growth factor receptor activity	10/2914	51/18639	0.196078431372549	1.25418870362146	0.268297748273695	0.625538947309808
GO:0005030	neurotrophin receptor activity	10/2914	51/18639	0.196078431372549	1.25418870362146	0.268297748273695	0.625538947309808
GO:0004549	tRNA-specific ribonuclease activity	4/2914	17/18639	0.235294117647059	1.50502644434575	0.269303021122803	0.625538947309808
GO:0008429	phosphatidylethanolamine binding	4/2914	17/18639	0.235294117647059	1.50502644434575	0.269303021122803	0.625538947309808
GO:0008484	sulfuric ester hydrolase activity	4/2914	17/18639	0.235294117647059	1.50502644434575	0.269303021122803	0.625538947309808
GO:0032977	membrane insertase activity	4/2914	17/18639	0.235294117647059	1.50502644434575	0.269303021122803	0.625538947309808
GO:0046965	nuclear retinoid X receptor binding	4/2914	17/18639	0.235294117647059	1.50502644434575	0.269303021122803	0.625538947309808
GO:0070492	oligosaccharide binding	4/2914	17/18639	0.235294117647059	1.50502644434575	0.269303021122803	0.625538947309808
GO:0070279	vitamin B6 binding	11/2914	57/18639	0.192982456140351	1.2343857240906	0.271704788619429	0.630012504609675
GO:0001216	DNA-binding transcription activator activity	82/2914	491/18639	0.167006109979633	1.06823160051832	0.272467871183422	0.630677380151836
GO:0015020	glucuronosyltransferase activity	7/2914	34/18639	0.205882352941176	1.31689813880254	0.275375251625535	0.632980613111474
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	7/2914	34/18639	0.205882352941176	1.31689813880254	0.275375251625535	0.632980613111474
GO:0016831	carboxy-lyase activity	7/2914	34/18639	0.205882352941176	1.31689813880254	0.275375251625535	0.632980613111474
GO:0090482	vitamin transmembrane transporter activity	7/2914	34/18639	0.205882352941176	1.31689813880254	0.275375251625535	0.632980613111474
GO:0003774	cytoskeletal motor activity	27/2914	153/18639	0.176470588235294	1.12876983325932	0.276459202057262	0.634370855327236
GO:0004175	endopeptidase activity	68/2914	405/18639	0.167901234567901	1.07395714176771	0.278056674802023	0.636932590722974
GO:0004532	RNA exonuclease activity	8/2914	40/18639	0.2	1.27927247769389	0.281636453008239	0.637780810282452
GO:0061791	GTPase motor activity	8/2914	40/18639	0.2	1.27927247769389	0.281636453008239	0.637780810282452
GO:1990606	membrane scission GTPase motor activity	8/2914	40/18639	0.2	1.27927247769389	0.281636453008239	0.637780810282452
GO:0005319	lipid transporter activity	31/2914	178/18639	0.174157303370787	1.11397322495816	0.284324670869261	0.637780810282452
GO:0031681	G-protein beta-subunit binding	5/2914	23/18639	0.217391304347826	1.39051356271075	0.285318613003076	0.637780810282452
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	9/2914	46/18639	0.195652173913043	1.25146220643968	0.286118570779454	0.637780810282452
GO:0005095	GTPase inhibitor activity	3/2914	12/18639	0.25	1.59909059711736	0.286134291017958	0.637780810282452
GO:0008179	adenylate cyclase binding	3/2914	12/18639	0.25	1.59909059711736	0.286134291017958	0.637780810282452
GO:0008504	monoamine transmembrane transporter activity	3/2914	12/18639	0.25	1.59909059711736	0.286134291017958	0.637780810282452
GO:0008603	cAMP-dependent protein kinase regulator activity	3/2914	12/18639	0.25	1.59909059711736	0.286134291017958	0.637780810282452
GO:0015132	prostaglandin transmembrane transporter activity	3/2914	12/18639	0.25	1.59909059711736	0.286134291017958	0.637780810282452
GO:0016423	tRNA (guanine) methyltransferase activity	3/2914	12/18639	0.25	1.59909059711736	0.286134291017958	0.637780810282452
GO:0016840	carbon-nitrogen lyase activity	3/2914	12/18639	0.25	1.59909059711736	0.286134291017958	0.637780810282452
GO:0034452	dynactin binding	3/2914	12/18639	0.25	1.59909059711736	0.286134291017958	0.637780810282452
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	3/2914	12/18639	0.25	1.59909059711736	0.286134291017958	0.637780810282452
GO:1990817	poly(A) RNA polymerase activity	3/2914	12/18639	0.25	1.59909059711736	0.286134291017958	0.637780810282452
GO:0004518	nuclease activity	36/2914	209/18639	0.172248803827751	1.10176577026268	0.289049588798545	0.643179406058595
GO:0019209	kinase activator activity	26/2914	148/18639	0.175675675675676	1.12368528446085	0.289527889736346	0.643179406058595
GO:0016782	transferase activity, transferring sulphur-containing groups	13/2914	70/18639	0.185714285714286	1.18789587214433	0.294438230590656	0.652991988780617
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	6/2914	29/18639	0.206896551724138	1.3233853217523	0.295224612661296	0.65364111565812
GO:0004866	endopeptidase inhibitor activity	28/2914	161/18639	0.173913043478261	1.1124108501686	0.299538823034879	0.662085812517829
GO:0004386	helicase activity	27/2914	155/18639	0.174193548387097	1.11420506121726	0.300810765763589	0.663512254556755
GO:0005154	epidermal growth factor receptor binding	7/2914	35/18639	0.2	1.27927247769389	0.301687596105111	0.663512254556755
GO:0140566	histone reader activity	7/2914	35/18639	0.2	1.27927247769389	0.301687596105111	0.663512254556755
GO:0015175	neutral L-amino acid transmembrane transporter activity	8/2914	41/18639	0.195121951219512	1.24807070994526	0.306012368779429	0.666149093977563
GO:0016877	ligase activity, forming carbon-sulfur bonds	8/2914	41/18639	0.195121951219512	1.24807070994526	0.306012368779429	0.666149093977563
GO:0140828	metal cation:monoatomic cation antiporter activity	8/2914	41/18639	0.195121951219512	1.24807070994526	0.306012368779429	0.666149093977563
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	4/2914	18/18639	0.222222222222222	1.42141386410432	0.306911591636188	0.666149093977563
GO:0008409	5'-3' exonuclease activity	4/2914	18/18639	0.222222222222222	1.42141386410432	0.306911591636188	0.666149093977563
GO:0016854	racemase and epimerase activity	4/2914	18/18639	0.222222222222222	1.42141386410432	0.306911591636188	0.666149093977563
GO:0030228	lipoprotein particle receptor activity	4/2914	18/18639	0.222222222222222	1.42141386410432	0.306911591636188	0.666149093977563
GO:0031690	adrenergic receptor binding	4/2914	18/18639	0.222222222222222	1.42141386410432	0.306911591636188	0.666149093977563
GO:0005504	fatty acid binding	9/2914	47/18639	0.191489361702128	1.22483535098351	0.308917999433339	0.669406597790084
GO:0038064	collagen receptor activity	10/2914	53/18639	0.188679245283019	1.20686082801311	0.310835168156736	0.6724603964698
GO:0120013	lipid transfer activity	12/2914	65/18639	0.184615384615385	1.18086690248667	0.312710595161001	0.675414075029633
GO:0031406	carboxylic acid binding	32/2914	187/18639	0.171122994652406	1.09456468679691	0.317012028158136	0.677735267398869
GO:0005315	phosphate transmembrane transporter activity	5/2914	24/18639	0.208333333333333	1.3325754975978	0.318047710829605	0.677735267398869
GO:0030215	semaphorin receptor binding	5/2914	24/18639	0.208333333333333	1.3325754975978	0.318047710829605	0.677735267398869
GO:0060229	lipase activator activity	5/2914	24/18639	0.208333333333333	1.3325754975978	0.318047710829605	0.677735267398869
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	5/2914	24/18639	0.208333333333333	1.3325754975978	0.318047710829605	0.677735267398869
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	31/2914	181/18639	0.171270718232044	1.0955095803456	0.318750669463739	0.677735267398869
GO:0042277	peptide binding	42/2914	249/18639	0.168674698795181	1.07890449925991	0.320174340099478	0.677735267398869
GO:0032182	ubiquitin-like protein binding	21/2914	120/18639	0.175	1.11936341798215	0.322256026952087	0.677735267398869
GO:0001965	G-protein alpha-subunit binding	6/2914	30/18639	0.2	1.27927247769389	0.324558138292033	0.677735267398869
GO:0033612	receptor serine/threonine kinase binding	6/2914	30/18639	0.2	1.27927247769389	0.324558138292033	0.677735267398869
GO:0035925	mRNA 3'-UTR AU-rich region binding	6/2914	30/18639	0.2	1.27927247769389	0.324558138292033	0.677735267398869
GO:0070566	adenylyltransferase activity	6/2914	30/18639	0.2	1.27927247769389	0.324558138292033	0.677735267398869
GO:0008238	exopeptidase activity	18/2914	102/18639	0.176470588235294	1.12876983325932	0.326424191973133	0.677735267398869
GO:0044390	ubiquitin-like protein conjugating enzyme binding	7/2914	36/18639	0.194444444444444	1.24373713109128	0.328481742145926	0.677735267398869
GO:0045505	dynein intermediate chain binding	7/2914	36/18639	0.194444444444444	1.24373713109128	0.328481742145926	0.677735267398869
GO:0055106	ubiquitin-protein transferase regulator activity	7/2914	36/18639	0.194444444444444	1.24373713109128	0.328481742145926	0.677735267398869
GO:0046943	carboxylic acid transmembrane transporter activity	32/2914	188/18639	0.170212765957447	1.08874253420757	0.328552503296915	0.677735267398869
GO:0004527	exonuclease activity	15/2914	84/18639	0.178571428571429	1.14220756936955	0.330015618101572	0.677735267398869
GO:0031492	nucleosomal DNA binding	8/2914	42/18639	0.19047619047619	1.21835474066085	0.330813868120821	0.677735267398869
GO:0030295	protein kinase activator activity	24/2914	139/18639	0.172661870503597	1.10440789441199	0.331287891953129	0.677735267398869
GO:0005126	cytokine receptor binding	46/2914	275/18639	0.167272727272727	1.06993698134398	0.331949502550199	0.677735267398869
GO:0002161	aminoacyl-tRNA editing activity	3/2914	13/18639	0.230769230769231	1.47608362810834	0.332218563653136	0.677735267398869
GO:0015651	quaternary ammonium group transmembrane transporter activity	3/2914	13/18639	0.230769230769231	1.47608362810834	0.332218563653136	0.677735267398869
GO:0035673	oligopeptide transmembrane transporter activity	3/2914	13/18639	0.230769230769231	1.47608362810834	0.332218563653136	0.677735267398869
GO:0043560	insulin receptor substrate binding	3/2914	13/18639	0.230769230769231	1.47608362810834	0.332218563653136	0.677735267398869
GO:0046974	histone H3K9 methyltransferase activity	3/2914	13/18639	0.230769230769231	1.47608362810834	0.332218563653136	0.677735267398869
GO:0051011	microtubule minus-end binding	3/2914	13/18639	0.230769230769231	1.47608362810834	0.332218563653136	0.677735267398869
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	3/2914	13/18639	0.230769230769231	1.47608362810834	0.332218563653136	0.677735267398869
GO:0070700	BMP receptor binding	3/2914	13/18639	0.230769230769231	1.47608362810834	0.332218563653136	0.677735267398869
GO:0071837	HMG box domain binding	3/2914	13/18639	0.230769230769231	1.47608362810834	0.332218563653136	0.677735267398869
GO:0140666	annealing activity	3/2914	13/18639	0.230769230769231	1.47608362810834	0.332218563653136	0.677735267398869
GO:0140852	histone ubiquitin ligase activity	3/2914	13/18639	0.230769230769231	1.47608362810834	0.332218563653136	0.677735267398869
GO:0008235	metalloexopeptidase activity	12/2914	66/18639	0.181818181818182	1.16297497972172	0.332405607695271	0.677735267398869
GO:0015485	cholesterol binding	10/2914	54/18639	0.185185185185185	1.18451155342027	0.332669261576449	0.677735267398869
GO:0001098	basal transcription machinery binding	11/2914	60/18639	0.183333333333333	1.17266643788607	0.332725017982828	0.677735267398869
GO:0001099	basal RNA polymerase II transcription machinery binding	11/2914	60/18639	0.183333333333333	1.17266643788607	0.332725017982828	0.677735267398869
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	11/2914	60/18639	0.183333333333333	1.17266643788607	0.332725017982828	0.677735267398869
GO:0004540	RNA nuclease activity	21/2914	121/18639	0.173553719008264	1.11011248064346	0.33679827562787	0.684978367021966
GO:0005342	organic acid transmembrane transporter activity	32/2914	189/18639	0.169312169312169	1.08298199169853	0.340213151589293	0.690862289423657
GO:0005229	intracellularly calcium-gated chloride channel activity	4/2914	19/18639	0.210526315789474	1.34660260809883	0.344989133207692	0.694027610944473
GO:0022821	solute:potassium antiporter activity	4/2914	19/18639	0.210526315789474	1.34660260809883	0.344989133207692	0.694027610944473
GO:0042800	histone H3K4 methyltransferase activity	4/2914	19/18639	0.210526315789474	1.34660260809883	0.344989133207692	0.694027610944473
GO:0120227	acyl-CoA binding	4/2914	19/18639	0.210526315789474	1.34660260809883	0.344989133207692	0.694027610944473
GO:0141147	intracellularly calcium-gated channel activity	4/2914	19/18639	0.210526315789474	1.34660260809883	0.344989133207692	0.694027610944473
GO:1990380	K48-linked deubiquitinase activity	4/2914	19/18639	0.210526315789474	1.34660260809883	0.344989133207692	0.694027610944473
GO:0000030	mannosyltransferase activity	5/2914	25/18639	0.2	1.27927247769389	0.351185065251101	0.694027610944473
GO:0003707	nuclear steroid receptor activity	5/2914	25/18639	0.2	1.27927247769389	0.351185065251101	0.694027610944473
GO:0015662	P-type ion transporter activity	5/2914	25/18639	0.2	1.27927247769389	0.351185065251101	0.694027610944473
GO:0017056	structural constituent of nuclear pore	5/2914	25/18639	0.2	1.27927247769389	0.351185065251101	0.694027610944473
GO:0042974	nuclear retinoic acid receptor binding	5/2914	25/18639	0.2	1.27927247769389	0.351185065251101	0.694027610944473
GO:0140358	P-type transmembrane transporter activity	5/2914	25/18639	0.2	1.27927247769389	0.351185065251101	0.694027610944473
GO:0005164	tumor necrosis factor receptor binding	6/2914	31/18639	0.193548387096774	1.23800562357473	0.35425768276588	0.694027610944473
GO:0070325	lipoprotein particle receptor binding	6/2914	31/18639	0.193548387096774	1.23800562357473	0.35425768276588	0.694027610944473
GO:0098632	cell-cell adhesion mediator activity	10/2914	55/18639	0.181818181818182	1.16297497972172	0.354776148996272	0.694027610944473
GO:0005004	GPI-linked ephrin receptor activity	9/2914	49/18639	0.183673469387755	1.17484207135153	0.355573699803032	0.694027610944473
GO:0005008	hepatocyte growth factor receptor activity	9/2914	49/18639	0.183673469387755	1.17484207135153	0.355573699803032	0.694027610944473
GO:0005009	insulin receptor activity	9/2914	49/18639	0.183673469387755	1.17484207135153	0.355573699803032	0.694027610944473
GO:0005011	macrophage colony-stimulating factor receptor activity	9/2914	49/18639	0.183673469387755	1.17484207135153	0.355573699803032	0.694027610944473
GO:0005018	platelet-derived growth factor alpha-receptor activity	9/2914	49/18639	0.183673469387755	1.17484207135153	0.355573699803032	0.694027610944473
GO:0005020	stem cell factor receptor activity	9/2914	49/18639	0.183673469387755	1.17484207135153	0.355573699803032	0.694027610944473
GO:0008288	boss receptor activity	9/2914	49/18639	0.183673469387755	1.17484207135153	0.355573699803032	0.694027610944473
GO:0036332	placental growth factor receptor activity	9/2914	49/18639	0.183673469387755	1.17484207135153	0.355573699803032	0.694027610944473
GO:0038062	protein tyrosine kinase collagen receptor activity	9/2914	49/18639	0.183673469387755	1.17484207135153	0.355573699803032	0.694027610944473
GO:0060175	brain-derived neurotrophic factor receptor activity	9/2914	49/18639	0.183673469387755	1.17484207135153	0.355573699803032	0.694027610944473
GO:0030551	cyclic nucleotide binding	7/2914	37/18639	0.189189189189189	1.21012261403476	0.355610328906553	0.694027610944473
GO:0004712	protein serine/threonine/tyrosine kinase activity	8/2914	43/18639	0.186046511627907	1.19002090948269	0.355925036126357	0.694027610944473
GO:0003684	damaged DNA binding	13/2914	74/18639	0.175675675675676	1.12368528446085	0.370114651918723	0.718979054673386
GO:0170055	lipid transmembrane transporter activity	10/2914	56/18639	0.178571428571429	1.14220756936955	0.37707791829625	0.718979054673386
GO:0004705	JUN kinase activity	3/2914	14/18639	0.214285714285714	1.37064908324346	0.37816990477944	0.718979054673386
GO:0008195	phosphatidate phosphatase activity	3/2914	14/18639	0.214285714285714	1.37064908324346	0.37816990477944	0.718979054673386
GO:0008331	high voltage-gated calcium channel activity	3/2914	14/18639	0.214285714285714	1.37064908324346	0.37816990477944	0.718979054673386
GO:0015926	glucosidase activity	3/2914	14/18639	0.214285714285714	1.37064908324346	0.37816990477944	0.718979054673386
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	3/2914	14/18639	0.214285714285714	1.37064908324346	0.37816990477944	0.718979054673386
GO:0030983	mismatched DNA binding	3/2914	14/18639	0.214285714285714	1.37064908324346	0.37816990477944	0.718979054673386
GO:0032036	myosin heavy chain binding	3/2914	14/18639	0.214285714285714	1.37064908324346	0.37816990477944	0.718979054673386
GO:0061665	SUMO ligase activity	3/2914	14/18639	0.214285714285714	1.37064908324346	0.37816990477944	0.718979054673386
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	3/2914	14/18639	0.214285714285714	1.37064908324346	0.37816990477944	0.718979054673386
GO:1901612	cardiolipin binding	3/2914	14/18639	0.214285714285714	1.37064908324346	0.37816990477944	0.718979054673386
GO:0005006	epidermal growth factor receptor activity	9/2914	50/18639	0.18	1.1513452299245	0.37924265366227	0.718979054673386
GO:0005007	fibroblast growth factor receptor activity	9/2914	50/18639	0.18	1.1513452299245	0.37924265366227	0.718979054673386
GO:0005017	platelet-derived growth factor receptor activity	9/2914	50/18639	0.18	1.1513452299245	0.37924265366227	0.718979054673386
GO:0005019	platelet-derived growth factor beta-receptor activity	9/2914	50/18639	0.18	1.1513452299245	0.37924265366227	0.718979054673386
GO:0032813	tumor necrosis factor receptor superfamily binding	9/2914	50/18639	0.18	1.1513452299245	0.37924265366227	0.718979054673386
GO:0016790	thiolester hydrolase activity	8/2914	44/18639	0.181818181818182	1.16297497972172	0.381231780286235	0.718979054673386
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	7/2914	38/18639	0.184210526315789	1.17827728208648	0.382929585699436	0.718979054673386
GO:0000339	RNA cap binding	4/2914	20/18639	0.2	1.27927247769389	0.383139527218426	0.718979054673386
GO:0010851	cyclase regulator activity	4/2914	20/18639	0.2	1.27927247769389	0.383139527218426	0.718979054673386
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	4/2914	20/18639	0.2	1.27927247769389	0.383139527218426	0.718979054673386
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	6/2914	32/18639	0.1875	1.19931794783802	0.384134758579885	0.718979054673386
GO:0042910	xenobiotic transmembrane transporter activity	6/2914	32/18639	0.1875	1.19931794783802	0.384134758579885	0.718979054673386
GO:0043425	bHLH transcription factor binding	6/2914	32/18639	0.1875	1.19931794783802	0.384134758579885	0.718979054673386
GO:0008157	protein phosphatase 1 binding	5/2914	26/18639	0.192307692307692	1.23006969009028	0.384469162166735	0.718979054673386
GO:0030247	polysaccharide binding	5/2914	26/18639	0.192307692307692	1.23006969009028	0.384469162166735	0.718979054673386
GO:0030507	spectrin binding	5/2914	26/18639	0.192307692307692	1.23006969009028	0.384469162166735	0.718979054673386
GO:0043548	phosphatidylinositol 3-kinase binding	5/2914	26/18639	0.192307692307692	1.23006969009028	0.384469162166735	0.718979054673386
GO:0005262	calcium channel activity	22/2914	131/18639	0.16793893129771	1.07419826371243	0.392948401887578	0.733799272354235
GO:0043130	ubiquitin binding	17/2914	100/18639	0.17	1.08738160603981	0.394159829732502	0.735024809247651
GO:0042562	hormone binding	16/2914	94/18639	0.170212765957447	1.08874253420757	0.397650646319014	0.740491498911919
GO:0019956	chemokine binding	6/2914	33/18639	0.181818181818182	1.16297497972172	0.414010585523806	0.765470754735224
GO:0005044	scavenger receptor activity	5/2914	27/18639	0.185185185185185	1.18451155342027	0.417657183019807	0.765470754735224
GO:0005385	zinc ion transmembrane transporter activity	5/2914	27/18639	0.185185185185185	1.18451155342027	0.417657183019807	0.765470754735224
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	4/2914	21/18639	0.19047619047619	1.21835474066085	0.421007520350972	0.765470754735224
GO:0005123	death receptor binding	4/2914	21/18639	0.19047619047619	1.21835474066085	0.421007520350972	0.765470754735224
GO:0010314	phosphatidylinositol-5-phosphate binding	4/2914	21/18639	0.19047619047619	1.21835474066085	0.421007520350972	0.765470754735224
GO:0015125	bile acid transmembrane transporter activity	4/2914	21/18639	0.19047619047619	1.21835474066085	0.421007520350972	0.765470754735224
GO:0036122	BMP binding	4/2914	21/18639	0.19047619047619	1.21835474066085	0.421007520350972	0.765470754735224
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	4/2914	21/18639	0.19047619047619	1.21835474066085	0.421007520350972	0.765470754735224
GO:0000774	adenyl-nucleotide exchange factor activity	3/2914	15/18639	0.2	1.27927247769389	0.423400827564327	0.765470754735224
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	3/2914	15/18639	0.2	1.27927247769389	0.423400827564327	0.765470754735224
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	3/2914	15/18639	0.2	1.27927247769389	0.423400827564327	0.765470754735224
GO:0015556	C4-dicarboxylate transmembrane transporter activity	3/2914	15/18639	0.2	1.27927247769389	0.423400827564327	0.765470754735224
GO:0015929	hexosaminidase activity	3/2914	15/18639	0.2	1.27927247769389	0.423400827564327	0.765470754735224
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	3/2914	15/18639	0.2	1.27927247769389	0.423400827564327	0.765470754735224
GO:0016846	carbon-sulfur lyase activity	3/2914	15/18639	0.2	1.27927247769389	0.423400827564327	0.765470754735224
GO:0042809	nuclear vitamin D receptor binding	3/2914	15/18639	0.2	1.27927247769389	0.423400827564327	0.765470754735224
GO:0047372	monoacylglycerol lipase activity	3/2914	15/18639	0.2	1.27927247769389	0.423400827564327	0.765470754735224
GO:0061578	K63-linked deubiquitinase activity	3/2914	15/18639	0.2	1.27927247769389	0.423400827564327	0.765470754735224
GO:0005496	steroid binding	18/2914	108/18639	0.166666666666667	1.06606039807824	0.423564847876032	0.765470754735224
GO:0001540	amyloid-beta binding	14/2914	83/18639	0.168674698795181	1.07890449925991	0.423784035665347	0.765470754735224
GO:0008135	translation factor activity, RNA binding	14/2914	83/18639	0.168674698795181	1.07890449925991	0.423784035665347	0.765470754735224
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	9/2914	52/18639	0.173076923076923	1.10706272108125	0.426806799716808	0.769880385320236
GO:0015144	carbohydrate transmembrane transporter activity	7/2914	40/18639	0.175	1.11936341798215	0.437593679505779	0.786124873359094
GO:0050997	quaternary ammonium group binding	7/2914	40/18639	0.175	1.11936341798215	0.437593679505779	0.786124873359094
GO:0140662	ATP-dependent protein folding chaperone	7/2914	40/18639	0.175	1.11936341798215	0.437593679505779	0.786124873359094
GO:0180051	translation factor activity	14/2914	84/18639	0.166666666666667	1.06606039807824	0.442537719178102	0.793895729682741
GO:0008175	tRNA methyltransferase activity	6/2914	34/18639	0.176470588235294	1.12876983325932	0.443718157073435	0.793895729682741
GO:0030332	cyclin binding	6/2914	34/18639	0.176470588235294	1.12876983325932	0.443718157073435	0.793895729682741
GO:0005253	monoatomic anion channel activity	17/2914	103/18639	0.16504854368932	1.05571029712603	0.444898019391145	0.794000720924912
GO:0030246	carbohydrate binding	45/2914	280/18639	0.160714285714286	1.02798681243259	0.444976234838584	0.794000720924912
GO:0051119	sugar transmembrane transporter activity	5/2914	28/18639	0.178571428571429	1.14220756936955	0.450527725328431	0.799597090116141
GO:0005003	ephrin receptor activity	9/2914	53/18639	0.169811320754717	1.08617474521179	0.450528269808641	0.799597090116141
GO:0005005	transmembrane-ephrin receptor activity	9/2914	53/18639	0.169811320754717	1.08617474521179	0.450528269808641	0.799597090116141
GO:0005246	calcium channel regulator activity	9/2914	53/18639	0.169811320754717	1.08617474521179	0.450528269808641	0.799597090116141
GO:0140938	histone H3 methyltransferase activity	8/2914	47/18639	0.170212765957447	1.08874253420757	0.45723860889559	0.810420238524445
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	4/2914	22/18639	0.181818181818182	1.16297497972172	0.458281601463177	0.811182941627334
GO:0016779	nucleotidyltransferase activity	22/2914	136/18639	0.161764705882353	1.03470568048771	0.466870326999828	0.815951653407698
GO:1990782	protein tyrosine kinase binding	19/2914	117/18639	0.162393162393162	1.03872551607624	0.467268212220235	0.815951653407698
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	3/2914	16/18639	0.1875	1.19931794783802	0.467432938099055	0.815951653407698
GO:0004707	MAP kinase activity	3/2914	16/18639	0.1875	1.19931794783802	0.467432938099055	0.815951653407698
GO:0004708	MAP kinase kinase activity	3/2914	16/18639	0.1875	1.19931794783802	0.467432938099055	0.815951653407698
GO:0015385	sodium:proton antiporter activity	3/2914	16/18639	0.1875	1.19931794783802	0.467432938099055	0.815951653407698
GO:0015562	efflux transmembrane transporter activity	3/2914	16/18639	0.1875	1.19931794783802	0.467432938099055	0.815951653407698
GO:0043023	ribosomal large subunit binding	3/2914	16/18639	0.1875	1.19931794783802	0.467432938099055	0.815951653407698
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	3/2914	16/18639	0.1875	1.19931794783802	0.467432938099055	0.815951653407698
GO:0070411	I-SMAD binding	3/2914	16/18639	0.1875	1.19931794783802	0.467432938099055	0.815951653407698
GO:0000175	3'-5'-RNA exonuclease activity	6/2914	35/18639	0.171428571428571	1.09651926659476	0.473103790377227	0.815951653407698
GO:0016229	steroid dehydrogenase activity	6/2914	35/18639	0.171428571428571	1.09651926659476	0.473103790377227	0.815951653407698
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	2/2914	10/18639	0.2	1.27927247769389	0.478847760345756	0.815951653407698
GO:0004955	prostaglandin receptor activity	2/2914	10/18639	0.2	1.27927247769389	0.478847760345756	0.815951653407698
GO:0008140	cAMP response element binding protein binding	2/2914	10/18639	0.2	1.27927247769389	0.478847760345756	0.815951653407698
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	2/2914	10/18639	0.2	1.27927247769389	0.478847760345756	0.815951653407698
GO:0016303	1-phosphatidylinositol-3-kinase activity	2/2914	10/18639	0.2	1.27927247769389	0.478847760345756	0.815951653407698
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	2/2914	10/18639	0.2	1.27927247769389	0.478847760345756	0.815951653407698
GO:0031957	very long-chain fatty acid-CoA ligase activity	2/2914	10/18639	0.2	1.27927247769389	0.478847760345756	0.815951653407698
GO:0042975	peroxisome proliferator activated receptor binding	2/2914	10/18639	0.2	1.27927247769389	0.478847760345756	0.815951653407698
GO:0043208	glycosphingolipid binding	2/2914	10/18639	0.2	1.27927247769389	0.478847760345756	0.815951653407698
GO:0045322	unmethylated CpG binding	2/2914	10/18639	0.2	1.27927247769389	0.478847760345756	0.815951653407698
GO:0050308	sugar-phosphatase activity	2/2914	10/18639	0.2	1.27927247769389	0.478847760345756	0.815951653407698
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	2/2914	10/18639	0.2	1.27927247769389	0.478847760345756	0.815951653407698
GO:0051864	histone H3K36 demethylase activity	2/2914	10/18639	0.2	1.27927247769389	0.478847760345756	0.815951653407698
GO:0099122	RNA polymerase II C-terminal domain binding	2/2914	10/18639	0.2	1.27927247769389	0.478847760345756	0.815951653407698
GO:0141109	transporter activator activity	2/2914	10/18639	0.2	1.27927247769389	0.478847760345756	0.815951653407698
GO:1905394	retromer complex binding	2/2914	10/18639	0.2	1.27927247769389	0.478847760345756	0.815951653407698
GO:1990763	arrestin family protein binding	2/2914	10/18639	0.2	1.27927247769389	0.478847760345756	0.815951653407698
GO:0016836	hydro-lyase activity	10/2914	61/18639	0.163934426229508	1.04858399810975	0.488895423415096	0.832001980207696
GO:0001217	DNA-binding transcription repressor activity	44/2914	278/18639	0.158273381294964	1.01237390321099	0.490093475937844	0.832970169629917
GO:0035198	miRNA binding	7/2914	42/18639	0.166666666666667	1.06606039807824	0.491457965609282	0.834218392906012
GO:0004602	glutathione peroxidase activity	4/2914	23/18639	0.173913043478261	1.1124108501686	0.494694862191619	0.834364328078603
GO:0005212	structural constituent of eye lens	4/2914	23/18639	0.173913043478261	1.1124108501686	0.494694862191619	0.834364328078603
GO:0005283	amino acid:sodium symporter activity	4/2914	23/18639	0.173913043478261	1.1124108501686	0.494694862191619	0.834364328078603
GO:0042171	lysophosphatidic acid acyltransferase activity	4/2914	23/18639	0.173913043478261	1.1124108501686	0.494694862191619	0.834364328078603
GO:0071617	lysophospholipid acyltransferase activity	4/2914	23/18639	0.173913043478261	1.1124108501686	0.494694862191619	0.834364328078603
GO:0008374	O-acyltransferase activity	9/2914	55/18639	0.163636363636364	1.04667748174955	0.497446056283977	0.837937122798964
GO:0004869	cysteine-type endopeptidase inhibitor activity	6/2914	36/18639	0.166666666666667	1.06606039807824	0.502028200023487	0.844581114143706
GO:0030971	receptor tyrosine kinase binding	13/2914	81/18639	0.160493827160494	1.0265766796309	0.505941269672251	0.849174211215971
GO:0004029	aldehyde dehydrogenase (NAD+) activity	3/2914	17/18639	0.176470588235294	1.12876983325932	0.509889348879681	0.849174211215971
GO:0016018	cyclosporin A binding	3/2914	17/18639	0.176470588235294	1.12876983325932	0.509889348879681	0.849174211215971
GO:0030548	acetylcholine receptor regulator activity	3/2914	17/18639	0.176470588235294	1.12876983325932	0.509889348879681	0.849174211215971
GO:0032183	SUMO binding	3/2914	17/18639	0.176470588235294	1.12876983325932	0.509889348879681	0.849174211215971
GO:0036041	long-chain fatty acid binding	3/2914	17/18639	0.176470588235294	1.12876983325932	0.509889348879681	0.849174211215971
GO:0045125	bioactive lipid receptor activity	3/2914	17/18639	0.176470588235294	1.12876983325932	0.509889348879681	0.849174211215971
GO:0070403	NAD+ binding	3/2914	17/18639	0.176470588235294	1.12876983325932	0.509889348879681	0.849174211215971
GO:0015179	L-amino acid transmembrane transporter activity	10/2914	62/18639	0.161290322580645	1.03167135297894	0.510835333795087	0.84968088184007
GO:0031210	phosphatidylcholine binding	5/2914	30/18639	0.166666666666667	1.06606039807824	0.514547420902495	0.853438902309851
GO:0051721	protein phosphatase 2A binding	5/2914	30/18639	0.166666666666667	1.06606039807824	0.514547420902495	0.853438902309851
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	42/2914	268/18639	0.156716417910448	1.00241500117805	0.519418835985061	0.853438902309851
GO:0016279	protein-lysine N-methyltransferase activity	11/2914	69/18639	0.159420289855072	1.01970994598788	0.522839317733668	0.853438902309851
GO:0004622	lysophospholipase activity	4/2914	24/18639	0.166666666666667	1.06606039807824	0.530024292464021	0.853438902309851
GO:0050699	WW domain binding	4/2914	24/18639	0.166666666666667	1.06606039807824	0.530024292464021	0.853438902309851
GO:0019213	deacetylase activity	6/2914	37/18639	0.162162162162162	1.03724795488694	0.530367142820313	0.853438902309851
GO:0022829	wide pore channel activity	6/2914	37/18639	0.162162162162162	1.03724795488694	0.530367142820313	0.853438902309851
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	2/2914	11/18639	0.181818181818182	1.16297497972172	0.531787835653797	0.853438902309851
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	2/2914	11/18639	0.181818181818182	1.16297497972172	0.531787835653797	0.853438902309851
GO:0003953	NAD+ nucleosidase activity	2/2914	11/18639	0.181818181818182	1.16297497972172	0.531787835653797	0.853438902309851
GO:0004954	prostanoid receptor activity	2/2914	11/18639	0.181818181818182	1.16297497972172	0.531787835653797	0.853438902309851
GO:0015173	aromatic amino acid transmembrane transporter activity	2/2914	11/18639	0.181818181818182	1.16297497972172	0.531787835653797	0.853438902309851
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	2/2914	11/18639	0.181818181818182	1.16297497972172	0.531787835653797	0.853438902309851
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	2/2914	11/18639	0.181818181818182	1.16297497972172	0.531787835653797	0.853438902309851
GO:0019107	myristoyltransferase activity	2/2914	11/18639	0.181818181818182	1.16297497972172	0.531787835653797	0.853438902309851
GO:0019203	carbohydrate phosphatase activity	2/2914	11/18639	0.181818181818182	1.16297497972172	0.531787835653797	0.853438902309851
GO:0019206	nucleoside kinase activity	2/2914	11/18639	0.181818181818182	1.16297497972172	0.531787835653797	0.853438902309851
GO:0019215	intermediate filament binding	2/2914	11/18639	0.181818181818182	1.16297497972172	0.531787835653797	0.853438902309851
GO:0032404	mismatch repair complex binding	2/2914	11/18639	0.181818181818182	1.16297497972172	0.531787835653797	0.853438902309851
GO:0032794	GTPase activating protein binding	2/2914	11/18639	0.181818181818182	1.16297497972172	0.531787835653797	0.853438902309851
GO:0034056	estrogen response element binding	2/2914	11/18639	0.181818181818182	1.16297497972172	0.531787835653797	0.853438902309851
GO:0034511	U3 snoRNA binding	2/2914	11/18639	0.181818181818182	1.16297497972172	0.531787835653797	0.853438902309851
GO:0042608	T cell receptor binding	2/2914	11/18639	0.181818181818182	1.16297497972172	0.531787835653797	0.853438902309851
GO:0050786	RAGE receptor binding	2/2914	11/18639	0.181818181818182	1.16297497972172	0.531787835653797	0.853438902309851
GO:0070697	activin receptor binding	2/2914	11/18639	0.181818181818182	1.16297497972172	0.531787835653797	0.853438902309851
GO:0070990	snRNP binding	2/2914	11/18639	0.181818181818182	1.16297497972172	0.531787835653797	0.853438902309851
GO:0099528	G protein-coupled neurotransmitter receptor activity	2/2914	11/18639	0.181818181818182	1.16297497972172	0.531787835653797	0.853438902309851
GO:0140031	phosphorylation-dependent protein binding	2/2914	11/18639	0.181818181818182	1.16297497972172	0.531787835653797	0.853438902309851
GO:0015171	amino acid transmembrane transporter activity	16/2914	102/18639	0.156862745098039	1.00335096289717	0.536286460059815	0.859616553413068
GO:0016278	lysine N-methyltransferase activity	11/2914	70/18639	0.157142857142857	1.0051426610452	0.543303365537734	0.869810950389311
GO:0005452	solute:inorganic anion antiporter activity	5/2914	31/18639	0.161290322580645	1.03167135297894	0.545372370544152	0.869967492289707
GO:0016411	acylglycerol O-acyltransferase activity	5/2914	31/18639	0.161290322580645	1.03167135297894	0.545372370544152	0.869967492289707
GO:0070273	phosphatidylinositol-4-phosphate binding	5/2914	31/18639	0.161290322580645	1.03167135297894	0.545372370544152	0.869967492289707
GO:0008308	voltage-gated monoatomic anion channel activity	3/2914	18/18639	0.166666666666667	1.06606039807824	0.550484900328379	0.871820583773654
GO:0015172	acidic amino acid transmembrane transporter activity	3/2914	18/18639	0.166666666666667	1.06606039807824	0.550484900328379	0.871820583773654
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	3/2914	18/18639	0.166666666666667	1.06606039807824	0.550484900328379	0.871820583773654
GO:0050811	GABA receptor binding	3/2914	18/18639	0.166666666666667	1.06606039807824	0.550484900328379	0.871820583773654
GO:0099602	neurotransmitter receptor regulator activity	3/2914	18/18639	0.166666666666667	1.06606039807824	0.550484900328379	0.871820583773654
GO:1990381	ubiquitin-specific protease binding	3/2914	18/18639	0.166666666666667	1.06606039807824	0.550484900328379	0.871820583773654
GO:0003724	RNA helicase activity	12/2914	77/18639	0.155844155844156	0.996835696904331	0.553173819963331	0.874042997132638
GO:0004536	DNA nuclease activity	10/2914	64/18639	0.15625	0.999431623198353	0.553801870609225	0.874042997132638
GO:0003743	translation initiation factor activity	8/2914	51/18639	0.156862745098039	1.00335096289717	0.555188943042711	0.874042997132638
GO:0016597	amino acid binding	8/2914	51/18639	0.156862745098039	1.00335096289717	0.555188943042711	0.874042997132638
GO:0016830	carbon-carbon lyase activity	8/2914	51/18639	0.156862745098039	1.00335096289717	0.555188943042711	0.874042997132638
GO:0005109	frizzled binding	6/2914	38/18639	0.157894736842105	1.00995195607413	0.558011684780478	0.877443551840086
GO:0004709	MAP kinase kinase kinase activity	4/2914	25/18639	0.16	1.02341798215511	0.564088907171244	0.884897764330245
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	4/2914	25/18639	0.16	1.02341798215511	0.564088907171244	0.884897764330245
GO:0016798	hydrolase activity, acting on glycosyl bonds	20/2914	130/18639	0.153846153846154	0.984055752072224	0.568659939099741	0.890324249934037
GO:0008009	chemokine activity	7/2914	45/18639	0.155555555555556	0.994989704873027	0.568892987495616	0.890324249934037
GO:0030515	snoRNA binding	5/2914	32/18639	0.15625	0.999431623198353	0.575231187574571	0.891235403273692
GO:0000340	RNA 7-methylguanosine cap binding	2/2914	12/18639	0.166666666666667	1.06606039807824	0.580918544580964	0.891235403273692
GO:0003995	acyl-CoA dehydrogenase activity	2/2914	12/18639	0.166666666666667	1.06606039807824	0.580918544580964	0.891235403273692
GO:0004126	cytidine deaminase activity	2/2914	12/18639	0.166666666666667	1.06606039807824	0.580918544580964	0.891235403273692
GO:0005247	voltage-gated chloride channel activity	2/2914	12/18639	0.166666666666667	1.06606039807824	0.580918544580964	0.891235403273692
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	2/2914	12/18639	0.166666666666667	1.06606039807824	0.580918544580964	0.891235403273692
GO:0016208	AMP binding	2/2914	12/18639	0.166666666666667	1.06606039807824	0.580918544580964	0.891235403273692
GO:0016801	hydrolase activity, acting on ether bonds	2/2914	12/18639	0.166666666666667	1.06606039807824	0.580918544580964	0.891235403273692
GO:0016803	ether hydrolase activity	2/2914	12/18639	0.166666666666667	1.06606039807824	0.580918544580964	0.891235403273692
GO:0035014	phosphatidylinositol 3-kinase regulator activity	2/2914	12/18639	0.166666666666667	1.06606039807824	0.580918544580964	0.891235403273692
GO:0035251	UDP-glucosyltransferase activity	2/2914	12/18639	0.166666666666667	1.06606039807824	0.580918544580964	0.891235403273692
GO:0045295	gamma-catenin binding	2/2914	12/18639	0.166666666666667	1.06606039807824	0.580918544580964	0.891235403273692
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	2/2914	12/18639	0.166666666666667	1.06606039807824	0.580918544580964	0.891235403273692
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	2/2914	12/18639	0.166666666666667	1.06606039807824	0.580918544580964	0.891235403273692
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	2/2914	12/18639	0.166666666666667	1.06606039807824	0.580918544580964	0.891235403273692
GO:0070679	inositol 1,4,5 trisphosphate binding	2/2914	12/18639	0.166666666666667	1.06606039807824	0.580918544580964	0.891235403273692
GO:1990247	N6-methyladenosine-containing RNA reader activity	2/2914	12/18639	0.166666666666667	1.06606039807824	0.580918544580964	0.891235403273692
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	6/2914	39/18639	0.153846153846154	0.984055752072224	0.584868142946254	0.892284132977671
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	9/2914	59/18639	0.152542372881356	0.975716296546188	0.587237238728474	0.892284132977671
GO:0070063	RNA polymerase binding	9/2914	59/18639	0.152542372881356	0.975716296546188	0.587237238728474	0.892284132977671
GO:0008301	DNA binding, bending	3/2914	19/18639	0.157894736842105	1.00995195607413	0.589015356663508	0.892284132977671
GO:0030506	ankyrin binding	3/2914	19/18639	0.157894736842105	1.00995195607413	0.589015356663508	0.892284132977671
GO:0042577	lipid phosphatase activity	3/2914	19/18639	0.157894736842105	1.00995195607413	0.589015356663508	0.892284132977671
GO:0046527	glucosyltransferase activity	3/2914	19/18639	0.157894736842105	1.00995195607413	0.589015356663508	0.892284132977671
GO:0046624	sphingolipid transporter activity	3/2914	19/18639	0.157894736842105	1.00995195607413	0.589015356663508	0.892284132977671
GO:0050145	nucleoside monophosphate kinase activity	3/2914	19/18639	0.157894736842105	1.00995195607413	0.589015356663508	0.892284132977671
GO:0070003	threonine-type peptidase activity	3/2914	19/18639	0.157894736842105	1.00995195607413	0.589015356663508	0.892284132977671
GO:0097001	ceramide binding	3/2914	19/18639	0.157894736842105	1.00995195607413	0.589015356663508	0.892284132977671
GO:0008186	ATP-dependent activity, acting on RNA	12/2914	79/18639	0.151898734177215	0.971599350147259	0.591089128727161	0.892362607109192
GO:0016835	carbon-oxygen lyase activity	12/2914	79/18639	0.151898734177215	0.971599350147259	0.591089128727161	0.892362607109192
GO:0033293	monocarboxylic acid binding	12/2914	79/18639	0.151898734177215	0.971599350147259	0.591089128727161	0.892362607109192
GO:0004529	DNA exonuclease activity	4/2914	26/18639	0.153846153846154	0.984055752072224	0.596747042626609	0.899878228288874
GO:0016209	antioxidant activity	13/2914	86/18639	0.151162790697674	0.966891988954685	0.598425029316526	0.901381955421025
GO:0004864	protein phosphatase inhibitor activity	8/2914	53/18639	0.150943396226415	0.965488662410484	0.601287218673304	0.904663951731198
GO:0030296	protein tyrosine kinase activator activity	5/2914	33/18639	0.151515151515152	0.969145816434766	0.604020580797922	0.906758168702796
GO:0070851	growth factor receptor binding	21/2914	139/18639	0.151079136690647	0.966356907610494	0.604048870691742	0.906758168702796
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	9/2914	60/18639	0.15	0.959454358270419	0.608503685383171	0.912410962001494
GO:0043495	protein-membrane adaptor activity	7/2914	47/18639	0.148936170212766	0.952649717431621	0.617304455474528	0.922473023756518
GO:0061749	forked DNA-dependent helicase activity	7/2914	47/18639	0.148936170212766	0.952649717431621	0.617304455474528	0.922473023756518
GO:1990518	single-stranded 3'-5' DNA helicase activity	7/2914	47/18639	0.148936170212766	0.952649717431621	0.617304455474528	0.922473023756518
GO:0099106	ion channel regulator activity	24/2914	160/18639	0.15	0.959454358270419	0.621213949957473	0.923700523601118
GO:0140463	chromatin-protein adaptor activity	8/2914	54/18639	0.148148148148148	0.947609242736216	0.623406722537343	0.923700523601118
GO:0016408	C-acyltransferase activity	3/2914	20/18639	0.15	0.959454358270419	0.625346385389111	0.923700523601118
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	2/2914	13/18639	0.153846153846154	0.984055752072224	0.626136722931478	0.923700523601118
GO:0004535	poly(A)-specific ribonuclease activity	2/2914	13/18639	0.153846153846154	0.984055752072224	0.626136722931478	0.923700523601118
GO:0008035	high-density lipoprotein particle binding	2/2914	13/18639	0.153846153846154	0.984055752072224	0.626136722931478	0.923700523601118
GO:0009982	pseudouridine synthase activity	2/2914	13/18639	0.153846153846154	0.984055752072224	0.626136722931478	0.923700523601118
GO:0046975	histone H3K36 methyltransferase activity	2/2914	13/18639	0.153846153846154	0.984055752072224	0.626136722931478	0.923700523601118
GO:0089720	caspase binding	2/2914	13/18639	0.153846153846154	0.984055752072224	0.626136722931478	0.923700523601118
GO:0140333	glycerophospholipid flippase activity	2/2914	13/18639	0.153846153846154	0.984055752072224	0.626136722931478	0.923700523601118
GO:0140410	monoatomic cation:bicarbonate symporter activity	2/2914	13/18639	0.153846153846154	0.984055752072224	0.626136722931478	0.923700523601118
GO:0004364	glutathione transferase activity	4/2914	27/18639	0.148148148148148	0.947609242736216	0.627893105166923	0.923700523601118
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	4/2914	27/18639	0.148148148148148	0.947609242736216	0.627893105166923	0.923700523601118
GO:0035255	ionotropic glutamate receptor binding	4/2914	27/18639	0.148148148148148	0.947609242736216	0.627893105166923	0.923700523601118
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	9/2914	61/18639	0.147540983606557	0.943725598298772	0.629205115339184	0.924603299344151
GO:0008276	protein methyltransferase activity	14/2914	95/18639	0.147368421052632	0.942621825669183	0.638584864531595	0.93476995695472
GO:0016247	channel regulator activity	25/2914	168/18639	0.148809523809524	0.951839641141288	0.638925418950188	0.93476995695472
GO:0009378	four-way junction helicase activity	7/2914	48/18639	0.145833333333333	0.932802848318463	0.64035978169028	0.93476995695472
GO:0036121	double-stranded DNA helicase activity	7/2914	48/18639	0.145833333333333	0.932802848318463	0.64035978169028	0.93476995695472
GO:0043138	3'-5' DNA helicase activity	7/2914	48/18639	0.145833333333333	0.932802848318463	0.64035978169028	0.93476995695472
GO:0140693	molecular condensate scaffold activity	7/2914	48/18639	0.145833333333333	0.932802848318463	0.64035978169028	0.93476995695472
GO:0004896	cytokine receptor activity	14/2914	96/18639	0.145833333333333	0.932802848318463	0.654672003862943	0.949219153992296
GO:0046625	sphingolipid binding	4/2914	28/18639	0.142857142857143	0.913766055495637	0.657454001806672	0.949219153992296
GO:0046966	nuclear thyroid hormone receptor binding	4/2914	28/18639	0.142857142857143	0.913766055495637	0.657454001806672	0.949219153992296
GO:0005343	organic acid:sodium symporter activity	5/2914	35/18639	0.142857142857143	0.913766055495637	0.658084786272389	0.949219153992296
GO:0001846	opsonin binding	3/2914	21/18639	0.142857142857143	0.913766055495637	0.659402862895467	0.949219153992296
GO:0035613	RNA stem-loop binding	3/2914	21/18639	0.142857142857143	0.913766055495637	0.659402862895467	0.949219153992296
GO:0004520	DNA endonuclease activity	6/2914	42/18639	0.142857142857143	0.913766055495637	0.659992479853108	0.949219153992296
GO:0043175	RNA polymerase core enzyme binding	6/2914	42/18639	0.142857142857143	0.913766055495637	0.659992479853108	0.949219153992296
GO:0005254	chloride channel activity	12/2914	83/18639	0.144578313253012	0.924775285079922	0.662225518474993	0.949219153992296
GO:0141108	transporter regulator activity	25/2914	170/18639	0.147058823529412	0.940641527716097	0.663156711774737	0.949219153992296
GO:0019212	phosphatase inhibitor activity	8/2914	56/18639	0.142857142857143	0.913766055495637	0.665572096233113	0.949219153992296
GO:0005313	L-glutamate transmembrane transporter activity	2/2914	14/18639	0.142857142857143	0.913766055495637	0.667464525956818	0.949219153992296
GO:0005545	1-phosphatidylinositol binding	2/2914	14/18639	0.142857142857143	0.913766055495637	0.667464525956818	0.949219153992296
GO:0008474	palmitoyl-(protein) hydrolase activity	2/2914	14/18639	0.142857142857143	0.913766055495637	0.667464525956818	0.949219153992296
GO:0008494	translation activator activity	2/2914	14/18639	0.142857142857143	0.913766055495637	0.667464525956818	0.949219153992296
GO:0015386	potassium:proton antiporter activity	2/2914	14/18639	0.142857142857143	0.913766055495637	0.667464525956818	0.949219153992296
GO:0019992	diacylglycerol binding	2/2914	14/18639	0.142857142857143	0.913766055495637	0.667464525956818	0.949219153992296
GO:0031404	chloride ion binding	2/2914	14/18639	0.142857142857143	0.913766055495637	0.667464525956818	0.949219153992296
GO:0032454	histone H3K9 demethylase activity	2/2914	14/18639	0.142857142857143	0.913766055495637	0.667464525956818	0.949219153992296
GO:0042813	Wnt receptor activity	2/2914	14/18639	0.142857142857143	0.913766055495637	0.667464525956818	0.949219153992296
GO:0070742	C2H2 zinc finger domain binding	2/2914	14/18639	0.142857142857143	0.913766055495637	0.667464525956818	0.949219153992296
GO:0071933	Arp2/3 complex binding	2/2914	14/18639	0.142857142857143	0.913766055495637	0.667464525956818	0.949219153992296
GO:0098599	palmitoyl hydrolase activity	2/2914	14/18639	0.142857142857143	0.913766055495637	0.667464525956818	0.949219153992296
GO:1901474	azole transmembrane transporter activity	2/2914	14/18639	0.142857142857143	0.913766055495637	0.667464525956818	0.949219153992296
GO:0008028	monocarboxylic acid transmembrane transporter activity	10/2914	70/18639	0.142857142857143	0.913766055495637	0.672098614062157	0.954783868045383
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	13/2914	91/18639	0.142857142857143	0.913766055495637	0.682283097324787	0.967518598196712
GO:0015103	inorganic anion transmembrane transporter activity	24/2914	165/18639	0.145454545454545	0.930379983777376	0.682811536442212	0.967518598196712
GO:0004190	aspartic-type endopeptidase activity	5/2914	36/18639	0.138888888888889	0.888383665065202	0.683255203409309	0.967518598196712
GO:0005416	amino acid:monoatomic cation symporter activity	4/2914	29/18639	0.137931034482759	0.882256881168201	0.685385435620953	0.96766911574029
GO:0106222	lncRNA binding	4/2914	29/18639	0.137931034482759	0.882256881168201	0.685385435620953	0.96766911574029
GO:0004601	peroxidase activity	8/2914	57/18639	0.140350877192982	0.897735072065889	0.685554101634737	0.96766911574029
GO:0031683	G-protein beta/gamma-subunit complex binding	3/2914	22/18639	0.136363636363636	0.87223123479129	0.691158851542671	0.973504595151592
GO:0070034	telomerase RNA binding	3/2914	22/18639	0.136363636363636	0.87223123479129	0.691158851542671	0.973504595151592
GO:0015293	symporter activity	21/2914	146/18639	0.143835616438356	0.920024727108621	0.696027961241839	0.978509587851795
GO:0008408	3'-5' exonuclease activity	8/2914	58/18639	0.137931034482759	0.882256881168201	0.704771151737551	0.978509587851795
GO:0017116	single-stranded DNA helicase activity	8/2914	58/18639	0.137931034482759	0.882256881168201	0.704771151737551	0.978509587851795
GO:0004865	protein serine/threonine phosphatase inhibitor activity	2/2914	15/18639	0.133333333333333	0.852848318462594	0.70501278724797	0.978509587851795
GO:0004953	icosanoid receptor activity	2/2914	15/18639	0.133333333333333	0.852848318462594	0.70501278724797	0.978509587851795
GO:0010181	FMN binding	2/2914	15/18639	0.133333333333333	0.852848318462594	0.70501278724797	0.978509587851795
GO:0015116	sulfate transmembrane transporter activity	2/2914	15/18639	0.133333333333333	0.852848318462594	0.70501278724797	0.978509587851795
GO:0030553	cGMP binding	2/2914	15/18639	0.133333333333333	0.852848318462594	0.70501278724797	0.978509587851795
GO:0033130	acetylcholine receptor binding	2/2914	15/18639	0.133333333333333	0.852848318462594	0.70501278724797	0.978509587851795
GO:0034483	heparan sulfate sulfotransferase activity	2/2914	15/18639	0.133333333333333	0.852848318462594	0.70501278724797	0.978509587851795
GO:0048531	beta-1,3-galactosyltransferase activity	2/2914	15/18639	0.133333333333333	0.852848318462594	0.70501278724797	0.978509587851795
GO:0001046	core promoter sequence-specific DNA binding	6/2914	44/18639	0.136363636363636	0.87223123479129	0.705059023270855	0.978509587851795
GO:0030547	signaling receptor inhibitor activity	6/2914	44/18639	0.136363636363636	0.87223123479129	0.705059023270855	0.978509587851795
GO:0043014	alpha-tubulin binding	6/2914	44/18639	0.136363636363636	0.87223123479129	0.705059023270855	0.978509587851795
GO:0070001	aspartic-type peptidase activity	5/2914	37/18639	0.135135135135135	0.864373295739116	0.70714396287634	0.980375504553166
GO:0022839	monoatomic ion-gated channel activity	4/2914	30/18639	0.133333333333333	0.852848318462594	0.7116682071161	0.98561580148715
GO:0003887	DNA-directed DNA polymerase activity	3/2914	23/18639	0.130434782608696	0.834308137626451	0.720628449945329	0.995941615582062
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	3/2914	23/18639	0.130434782608696	0.834308137626451	0.720628449945329	0.995941615582062
GO:0015459	potassium channel regulator activity	8/2914	59/18639	0.135593220338983	0.867303374707723	0.723207843974269	0.996386249138327
GO:0036002	pre-mRNA binding	8/2914	59/18639	0.135593220338983	0.867303374707723	0.723207843974269	0.996386249138327
GO:0070888	E-box binding	8/2914	59/18639	0.135593220338983	0.867303374707723	0.723207843974269	0.996386249138327
GO:0008083	growth factor activity	23/2914	162/18639	0.141975308641975	0.908125524288874	0.725287294543424	0.998212451117977
GO:0005501	retinoid binding	5/2914	38/18639	0.131578947368421	0.841626630061771	0.729739762587834	1
GO:0019840	isoprenoid binding	5/2914	38/18639	0.131578947368421	0.841626630061771	0.729739762587834	1
GO:0042162	telomeric DNA binding	5/2914	38/18639	0.131578947368421	0.841626630061771	0.729739762587834	1
GO:0046873	metal ion transmembrane transporter activity	66/2914	450/18639	0.146666666666667	0.938133150308854	0.735323974270057	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	4/2914	31/18639	0.129032258064516	0.825337082383156	0.736304627348981	1
GO:0008327	methyl-CpG binding	4/2914	31/18639	0.129032258064516	0.825337082383156	0.736304627348981	1
GO:0047499	calcium-independent phospholipase A2 activity	4/2914	31/18639	0.129032258064516	0.825337082383156	0.736304627348981	1
GO:0072349	modified amino acid transmembrane transporter activity	4/2914	31/18639	0.129032258064516	0.825337082383156	0.736304627348981	1
GO:0005324	long-chain fatty acid transmembrane transporter activity	2/2914	16/18639	0.125	0.799545298558682	0.738952765697816	1
GO:0005521	lamin binding	2/2914	16/18639	0.125	0.799545298558682	0.738952765697816	1
GO:0008142	oxysterol binding	2/2914	16/18639	0.125	0.799545298558682	0.738952765697816	1
GO:0017070	U6 snRNA binding	2/2914	16/18639	0.125	0.799545298558682	0.738952765697816	1
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	2/2914	16/18639	0.125	0.799545298558682	0.738952765697816	1
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	2/2914	16/18639	0.125	0.799545298558682	0.738952765697816	1
GO:0140327	flippase activity	2/2914	16/18639	0.125	0.799545298558682	0.738952765697816	1
GO:0042054	histone methyltransferase activity	9/2914	67/18639	0.134328358208955	0.859212858152614	0.739927842986282	1
GO:0005544	calcium-dependent phospholipid binding	7/2914	53/18639	0.132075471698113	0.844802579609174	0.742708993292164	1
GO:0016251	RNA polymerase II general transcription initiation factor activity	7/2914	53/18639	0.132075471698113	0.844802579609174	0.742708993292164	1
GO:0017046	peptide hormone binding	7/2914	53/18639	0.132075471698113	0.844802579609174	0.742708993292164	1
GO:0015081	sodium ion transmembrane transporter activity	23/2914	164/18639	0.140243902439024	0.897050822773156	0.746854332596408	1
GO:0015149	hexose transmembrane transporter activity	3/2914	24/18639	0.125	0.799545298558682	0.747857615299802	1
GO:0015295	solute:proton symporter activity	3/2914	24/18639	0.125	0.799545298558682	0.747857615299802	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	3/2914	24/18639	0.125	0.799545298558682	0.747857615299802	1
GO:0048027	mRNA 5'-UTR binding	3/2914	24/18639	0.125	0.799545298558682	0.747857615299802	1
GO:0055056	D-glucose transmembrane transporter activity	3/2914	24/18639	0.125	0.799545298558682	0.747857615299802	1
GO:0070840	dynein complex binding	3/2914	24/18639	0.125	0.799545298558682	0.747857615299802	1
GO:0140612	DNA damage sensor activity	3/2914	24/18639	0.125	0.799545298558682	0.747857615299802	1
GO:0019787	ubiquitin-like protein transferase activity	70/2914	479/18639	0.146137787056367	0.934750244661507	0.751474928674276	1
GO:0015106	bicarbonate transmembrane transporter activity	4/2914	32/18639	0.125	0.799545298558682	0.759315118745325	1
GO:0047498	calcium-dependent phospholipase A2 activity	4/2914	32/18639	0.125	0.799545298558682	0.759315118745325	1
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	7/2914	54/18639	0.12962962962963	0.829158087394189	0.760477416596074	1
GO:0099095	ligand-gated monoatomic anion channel activity	6/2914	47/18639	0.127659574468085	0.816556900655675	0.764706321018984	1
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	2/2914	17/18639	0.117647058823529	0.752513222172877	0.7694945546069	1
GO:0004550	nucleoside diphosphate kinase activity	2/2914	17/18639	0.117647058823529	0.752513222172877	0.7694945546069	1
GO:0004659	prenyltransferase activity	2/2914	17/18639	0.117647058823529	0.752513222172877	0.7694945546069	1
GO:0005092	GDP-dissociation inhibitor activity	2/2914	17/18639	0.117647058823529	0.752513222172877	0.7694945546069	1
GO:0008569	minus-end-directed microtubule motor activity	2/2914	17/18639	0.117647058823529	0.752513222172877	0.7694945546069	1
GO:0009881	photoreceptor activity	2/2914	17/18639	0.117647058823529	0.752513222172877	0.7694945546069	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	2/2914	17/18639	0.117647058823529	0.752513222172877	0.7694945546069	1
GO:0016805	dipeptidase activity	2/2914	17/18639	0.117647058823529	0.752513222172877	0.7694945546069	1
GO:0038191	neuropilin binding	2/2914	17/18639	0.117647058823529	0.752513222172877	0.7694945546069	1
GO:0048038	quinone binding	2/2914	17/18639	0.117647058823529	0.752513222172877	0.7694945546069	1
GO:0051536	iron-sulfur cluster binding	10/2914	76/18639	0.131578947368421	0.841626630061771	0.769697056014903	1
GO:0140101	catalytic activity, acting on a tRNA	19/2914	139/18639	0.136690647482014	0.874322916409494	0.772173751966588	1
GO:0140767	enzyme-substrate adaptor activity	19/2914	139/18639	0.136690647482014	0.874322916409494	0.772173751966588	1
GO:0005251	delayed rectifier potassium channel activity	3/2914	25/18639	0.12	0.767563486616335	0.772916984590059	1
GO:0015271	outward rectifier potassium channel activity	3/2914	25/18639	0.12	0.767563486616335	0.772916984590059	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	3/2914	25/18639	0.12	0.767563486616335	0.772916984590059	1
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	3/2914	25/18639	0.12	0.767563486616335	0.772916984590059	1
GO:0016755	aminoacyltransferase activity	72/2914	496/18639	0.145161290322581	0.92850421768105	0.773851519372784	1
GO:0051540	metal cluster binding	10/2914	77/18639	0.12987012987013	0.830696414086942	0.783759088172168	1
GO:0017080	sodium channel regulator activity	5/2914	41/18639	0.121951219512195	0.780044193715787	0.789842599873311	1
GO:0042287	MHC protein binding	5/2914	41/18639	0.121951219512195	0.780044193715787	0.789842599873311	1
GO:0000149	SNARE binding	14/2914	106/18639	0.132075471698113	0.844802579609174	0.792242183309012	1
GO:0005227	calcium-activated cation channel activity	3/2914	26/18639	0.115384615384615	0.738041814054168	0.795895672672248	1
GO:0015145	monosaccharide transmembrane transporter activity	3/2914	26/18639	0.115384615384615	0.738041814054168	0.795895672672248	1
GO:0051139	metal cation:proton antiporter activity	3/2914	26/18639	0.115384615384615	0.738041814054168	0.795895672672248	1
GO:0097602	cullin family protein binding	3/2914	26/18639	0.115384615384615	0.738041814054168	0.795895672672248	1
GO:0003746	translation elongation factor activity	2/2914	18/18639	0.111111111111111	0.710706932052162	0.796870761391716	1
GO:0004706	JUN kinase kinase kinase activity	2/2914	18/18639	0.111111111111111	0.710706932052162	0.796870761391716	1
GO:0015280	ligand-gated sodium channel activity	2/2914	18/18639	0.111111111111111	0.710706932052162	0.796870761391716	1
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	2/2914	18/18639	0.111111111111111	0.710706932052162	0.796870761391716	1
GO:0034185	apolipoprotein binding	2/2914	18/18639	0.111111111111111	0.710706932052162	0.796870761391716	1
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	2/2914	18/18639	0.111111111111111	0.710706932052162	0.796870761391716	1
GO:0070628	proteasome binding	2/2914	18/18639	0.111111111111111	0.710706932052162	0.796870761391716	1
GO:0035254	glutamate receptor binding	6/2914	49/18639	0.122448979591837	0.783228047567689	0.79919775863033	1
GO:0140299	molecular sensor activity	9/2914	71/18639	0.126760563380282	0.810806499946833	0.799895993475023	1
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	4/2914	34/18639	0.117647058823529	0.752513222172877	0.800611871720331	1
GO:0140098	catalytic activity, acting on RNA	55/2914	387/18639	0.142118863049096	0.909043750299277	0.800904228039785	1
GO:0031490	chromatin DNA binding	17/2914	128/18639	0.1328125	0.8495168797186	0.80246714227922	1
GO:0008509	monoatomic anion transmembrane transporter activity	20/2914	149/18639	0.134228187919463	0.858572132680464	0.803149981099118	1
GO:0042056	chemoattractant activity	5/2914	42/18639	0.119047619047619	0.761471712913031	0.807389913389555	1
GO:0004842	ubiquitin-protein transferase activity	64/2914	449/18639	0.142538975501114	0.911730941786292	0.809947065867598	1
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	16/2914	122/18639	0.131147540983607	0.838867198487798	0.812855178479863	1
GO:0042379	chemokine receptor binding	9/2914	72/18639	0.125	0.799545298558682	0.813149990441732	1
GO:0101005	deubiquitinase activity	15/2914	115/18639	0.130434782608696	0.834308137626451	0.813472794227572	1
GO:0004843	cysteine-type deubiquitinase activity	14/2914	108/18639	0.12962962962963	0.829158087394189	0.814375390200892	1
GO:0048020	CCR chemokine receptor binding	6/2914	50/18639	0.12	0.767563486616335	0.814912248945464	1
GO:0005104	fibroblast growth factor receptor binding	3/2914	27/18639	0.111111111111111	0.710706932052162	0.816895993610414	1
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	3/2914	27/18639	0.111111111111111	0.710706932052162	0.816895993610414	1
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/2914	10/18639	0.1	0.639636238846946	0.817406175352102	1
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	1/2914	10/18639	0.1	0.639636238846946	0.817406175352102	1
GO:0004445	inositol-polyphosphate 5-phosphatase activity	1/2914	10/18639	0.1	0.639636238846946	0.817406175352102	1
GO:0004935	adrenergic receptor activity	1/2914	10/18639	0.1	0.639636238846946	0.817406175352102	1
GO:0008190	eukaryotic initiation factor 4E binding	1/2914	10/18639	0.1	0.639636238846946	0.817406175352102	1
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/2914	10/18639	0.1	0.639636238846946	0.817406175352102	1
GO:0008641	ubiquitin-like modifier activating enzyme activity	1/2914	10/18639	0.1	0.639636238846946	0.817406175352102	1
GO:0015187	glycine transmembrane transporter activity	1/2914	10/18639	0.1	0.639636238846946	0.817406175352102	1
GO:0015279	store-operated calcium channel activity	1/2914	10/18639	0.1	0.639636238846946	0.817406175352102	1
GO:0015643	toxic substance binding	1/2914	10/18639	0.1	0.639636238846946	0.817406175352102	1
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	1/2914	10/18639	0.1	0.639636238846946	0.817406175352102	1
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	1/2914	10/18639	0.1	0.639636238846946	0.817406175352102	1
GO:0019531	oxalate transmembrane transporter activity	1/2914	10/18639	0.1	0.639636238846946	0.817406175352102	1
GO:0019911	structural constituent of myelin sheath	1/2914	10/18639	0.1	0.639636238846946	0.817406175352102	1
GO:0032052	bile acid binding	1/2914	10/18639	0.1	0.639636238846946	0.817406175352102	1
GO:0032356	oxidized DNA binding	1/2914	10/18639	0.1	0.639636238846946	0.817406175352102	1
GO:0032395	MHC class II receptor activity	1/2914	10/18639	0.1	0.639636238846946	0.817406175352102	1
GO:0051880	G-quadruplex DNA binding	1/2914	10/18639	0.1	0.639636238846946	0.817406175352102	1
GO:0070097	delta-catenin binding	1/2914	10/18639	0.1	0.639636238846946	0.817406175352102	1
GO:0070513	death domain binding	1/2914	10/18639	0.1	0.639636238846946	0.817406175352102	1
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/2914	10/18639	0.1	0.639636238846946	0.817406175352102	1
GO:0097177	mitochondrial ribosome binding	1/2914	10/18639	0.1	0.639636238846946	0.817406175352102	1
GO:1990757	ubiquitin ligase activator activity	1/2914	10/18639	0.1	0.639636238846946	0.817406175352102	1
GO:0004623	phospholipase A2 activity	4/2914	35/18639	0.114285714285714	0.731012844396509	0.819002463391034	1
GO:0034061	DNA polymerase activity	4/2914	35/18639	0.114285714285714	0.731012844396509	0.819002463391034	1
GO:0043015	gamma-tubulin binding	4/2914	35/18639	0.114285714285714	0.731012844396509	0.819002463391034	1
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	2/2914	19/18639	0.105263157894737	0.673301304049417	0.821324338418563	1
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	2/2914	19/18639	0.105263157894737	0.673301304049417	0.821324338418563	1
GO:0015245	fatty acid transmembrane transporter activity	2/2914	19/18639	0.105263157894737	0.673301304049417	0.821324338418563	1
GO:0022840	leak channel activity	2/2914	19/18639	0.105263157894737	0.673301304049417	0.821324338418563	1
GO:0022842	narrow pore channel activity	2/2914	19/18639	0.105263157894737	0.673301304049417	0.821324338418563	1
GO:0042834	peptidoglycan binding	2/2914	19/18639	0.105263157894737	0.673301304049417	0.821324338418563	1
GO:0061980	regulatory RNA binding	7/2914	58/18639	0.120689655172414	0.771974771022176	0.822615038373416	1
GO:0061659	ubiquitin-like protein ligase activity	52/2914	372/18639	0.139784946236559	0.894115172581752	0.831267658788434	1
GO:0000993	RNA polymerase II complex binding	4/2914	36/18639	0.111111111111111	0.710706932052162	0.835970870888749	1
GO:0005484	SNAP receptor activity	4/2914	36/18639	0.111111111111111	0.710706932052162	0.835970870888749	1
GO:0016409	palmitoyltransferase activity	4/2914	36/18639	0.111111111111111	0.710706932052162	0.835970870888749	1
GO:0031593	polyubiquitin modification-dependent protein binding	7/2914	59/18639	0.11864406779661	0.758890452869258	0.835996776080993	1
GO:0051537	2 iron, 2 sulfur cluster binding	3/2914	28/18639	0.107142857142857	0.685324541621728	0.836029032626863	1
GO:0003678	DNA helicase activity	9/2914	74/18639	0.121621621621622	0.777935966165204	0.837643384951117	1
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	22/2914	167/18639	0.131736526946108	0.842634566145677	0.838055496591559	1
GO:0061630	ubiquitin protein ligase activity	49/2914	353/18639	0.138810198300283	0.887880331543919	0.838798142438002	1
GO:0001614	purinergic nucleotide receptor activity	2/2914	20/18639	0.1	0.639636238846946	0.843099666532947	1
GO:0001972	retinoic acid binding	2/2914	20/18639	0.1	0.639636238846946	0.843099666532947	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	2/2914	20/18639	0.1	0.639636238846946	0.843099666532947	1
GO:0016502	nucleotide receptor activity	2/2914	20/18639	0.1	0.639636238846946	0.843099666532947	1
GO:0042288	MHC class I protein binding	2/2914	20/18639	0.1	0.639636238846946	0.843099666532947	1
GO:0043024	ribosomal small subunit binding	2/2914	20/18639	0.1	0.639636238846946	0.843099666532947	1
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	1/2914	11/18639	0.0909090909090909	0.58148748986086	0.845968009321933	1
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/2914	11/18639	0.0909090909090909	0.58148748986086	0.845968009321933	1
GO:0005221	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	1/2914	11/18639	0.0909090909090909	0.58148748986086	0.845968009321933	1
GO:0008172	S-methyltransferase activity	1/2914	11/18639	0.0909090909090909	0.58148748986086	0.845968009321933	1
GO:0008271	secondary active sulfate transmembrane transporter activity	1/2914	11/18639	0.0909090909090909	0.58148748986086	0.845968009321933	1
GO:0008503	benzodiazepine receptor activity	1/2914	11/18639	0.0909090909090909	0.58148748986086	0.845968009321933	1
GO:0010854	adenylate cyclase regulator activity	1/2914	11/18639	0.0909090909090909	0.58148748986086	0.845968009321933	1
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/2914	11/18639	0.0909090909090909	0.58148748986086	0.845968009321933	1
GO:0016594	glycine binding	1/2914	11/18639	0.0909090909090909	0.58148748986086	0.845968009321933	1
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/2914	11/18639	0.0909090909090909	0.58148748986086	0.845968009321933	1
GO:0019864	IgG binding	1/2914	11/18639	0.0909090909090909	0.58148748986086	0.845968009321933	1
GO:0031731	CCR6 chemokine receptor binding	1/2914	11/18639	0.0909090909090909	0.58148748986086	0.845968009321933	1
GO:0043855	cyclic nucleotide-activated monoatomic ion channel activity	1/2914	11/18639	0.0909090909090909	0.58148748986086	0.845968009321933	1
GO:0045294	alpha-catenin binding	1/2914	11/18639	0.0909090909090909	0.58148748986086	0.845968009321933	1
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/2914	11/18639	0.0909090909090909	0.58148748986086	0.845968009321933	1
GO:0042605	peptide antigen binding	5/2914	45/18639	0.111111111111111	0.710706932052162	0.853087422661968	1
GO:0016417	S-acyltransferase activity	3/2914	29/18639	0.103448275862069	0.661692660876151	0.853410986127545	1
GO:0003777	microtubule motor activity	8/2914	68/18639	0.117647058823529	0.752513222172877	0.85401375442324	1
GO:0034212	protein N-acetyltransferase activity	6/2914	53/18639	0.113207547169811	0.724116496807863	0.85627292572905	1
GO:0019783	ubiquitin-like protein peptidase activity	16/2914	127/18639	0.125984251968504	0.805840930830798	0.858417487966779	1
GO:0019905	syntaxin binding	7/2914	61/18639	0.114754098360656	0.734008798676823	0.860340260797308	1
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	2/2914	21/18639	0.0952380952380952	0.609177370330425	0.862436172178997	1
GO:0005248	voltage-gated sodium channel activity	2/2914	21/18639	0.0952380952380952	0.609177370330425	0.862436172178997	1
GO:0004180	carboxypeptidase activity	5/2914	46/18639	0.108695652173913	0.695256781355376	0.866160393524675	1
GO:0003697	single-stranded DNA binding	15/2914	121/18639	0.12396694214876	0.7929374861739	0.868199906130594	1
GO:0017069	snRNA binding	6/2914	54/18639	0.111111111111111	0.710706932052162	0.868247364370672	1
GO:0048019	receptor antagonist activity	3/2914	30/18639	0.1	0.639636238846946	0.869160183795483	1
GO:0000995	RNA polymerase III general transcription initiation factor activity	1/2914	12/18639	0.0833333333333333	0.533030199039122	0.870063415207476	1
GO:0003720	telomerase activity	1/2914	12/18639	0.0833333333333333	0.533030199039122	0.870063415207476	1
GO:0004300	enoyl-CoA hydratase activity	1/2914	12/18639	0.0833333333333333	0.533030199039122	0.870063415207476	1
GO:0004875	complement receptor activity	1/2914	12/18639	0.0833333333333333	0.533030199039122	0.870063415207476	1
GO:0005049	nuclear export signal receptor activity	1/2914	12/18639	0.0833333333333333	0.533030199039122	0.870063415207476	1
GO:0015166	polyol transmembrane transporter activity	1/2914	12/18639	0.0833333333333333	0.533030199039122	0.870063415207476	1
GO:0035197	siRNA binding	1/2914	12/18639	0.0833333333333333	0.533030199039122	0.870063415207476	1
GO:0043047	single-stranded telomeric DNA binding	1/2914	12/18639	0.0833333333333333	0.533030199039122	0.870063415207476	1
GO:0097371	MDM2/MDM4 family protein binding	1/2914	12/18639	0.0833333333333333	0.533030199039122	0.870063415207476	1
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	1/2914	12/18639	0.0833333333333333	0.533030199039122	0.870063415207476	1
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	1/2914	12/18639	0.0833333333333333	0.533030199039122	0.870063415207476	1
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	1/2914	12/18639	0.0833333333333333	0.533030199039122	0.870063415207476	1
GO:0140829	bicarbonate:monoatomic anion antiporter activity	1/2914	12/18639	0.0833333333333333	0.533030199039122	0.870063415207476	1
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	1/2914	12/18639	0.0833333333333333	0.533030199039122	0.870063415207476	1
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	1/2914	12/18639	0.0833333333333333	0.533030199039122	0.870063415207476	1
GO:0140900	chloride:bicarbonate antiporter activity	1/2914	12/18639	0.0833333333333333	0.533030199039122	0.870063415207476	1
GO:1990459	transferrin receptor binding	1/2914	12/18639	0.0833333333333333	0.533030199039122	0.870063415207476	1
GO:0022843	voltage-gated monoatomic cation channel activity	18/2914	143/18639	0.125874125874126	0.805136524422729	0.871021821020022	1
GO:0061733	protein-lysine-acetyltransferase activity	5/2914	47/18639	0.106382978723404	0.68046408387973	0.878238259299162	1
GO:0033691	sialic acid binding	2/2914	22/18639	0.0909090909090909	0.58148748986086	0.87956390424263	1
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	16/2914	130/18639	0.123076923076923	0.787244601657779	0.88133522448593	1
GO:0140457	protein demethylase activity	3/2914	31/18639	0.0967741935483871	0.619002811787367	0.883394707700466	1
GO:0046982	protein heterodimerization activity	50/2914	369/18639	0.13550135501355	0.866715770795319	0.883563083904811	1
GO:0015294	solute:monoatomic cation symporter activity	14/2914	116/18639	0.120689655172414	0.771974771022176	0.885680603627463	1
GO:0015370	solute:sodium symporter activity	9/2914	79/18639	0.113924050632911	0.728699512610445	0.887903144275196	1
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	5/2914	48/18639	0.104166666666667	0.666287748798902	0.889374090339569	1
GO:0038187	pattern recognition receptor activity	5/2914	48/18639	0.104166666666667	0.666287748798902	0.889374090339569	1
GO:0003964	RNA-directed DNA polymerase activity	1/2914	13/18639	0.0769230769230769	0.492027876036112	0.890390639563809	1
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/2914	13/18639	0.0769230769230769	0.492027876036112	0.890390639563809	1
GO:0005035	death receptor activity	1/2914	13/18639	0.0769230769230769	0.492027876036112	0.890390639563809	1
GO:0005542	folic acid binding	1/2914	13/18639	0.0769230769230769	0.492027876036112	0.890390639563809	1
GO:0008253	5'-nucleotidase activity	1/2914	13/18639	0.0769230769230769	0.492027876036112	0.890390639563809	1
GO:0008417	fucosyltransferase activity	1/2914	13/18639	0.0769230769230769	0.492027876036112	0.890390639563809	1
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/2914	13/18639	0.0769230769230769	0.492027876036112	0.890390639563809	1
GO:0031432	titin binding	1/2914	13/18639	0.0769230769230769	0.492027876036112	0.890390639563809	1
GO:0039706	co-receptor binding	1/2914	13/18639	0.0769230769230769	0.492027876036112	0.890390639563809	1
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/2914	13/18639	0.0769230769230769	0.492027876036112	0.890390639563809	1
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/2914	13/18639	0.0769230769230769	0.492027876036112	0.890390639563809	1
GO:0097157	pre-mRNA intronic binding	1/2914	13/18639	0.0769230769230769	0.492027876036112	0.890390639563809	1
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	1/2914	13/18639	0.0769230769230769	0.492027876036112	0.890390639563809	1
GO:1901338	catecholamine binding	1/2914	13/18639	0.0769230769230769	0.492027876036112	0.890390639563809	1
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	2/2914	23/18639	0.0869565217391304	0.556205425084301	0.894700614175707	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	2/2914	23/18639	0.0869565217391304	0.556205425084301	0.894700614175707	1
GO:0008171	O-methyltransferase activity	2/2914	23/18639	0.0869565217391304	0.556205425084301	0.894700614175707	1
GO:0043274	phospholipase binding	2/2914	23/18639	0.0869565217391304	0.556205425084301	0.894700614175707	1
GO:0008168	methyltransferase activity	26/2914	204/18639	0.127450980392157	0.81522265735395	0.89490002416491	1
GO:0001530	lipopolysaccharide binding	4/2914	41/18639	0.0975609756097561	0.62403535497263	0.901988626256507	1
GO:0016407	acetyltransferase activity	11/2914	96/18639	0.114583333333333	0.732916523678792	0.902363231601152	1
GO:0008174	mRNA methyltransferase activity	1/2914	14/18639	0.0714285714285714	0.456883027747818	0.907538802148962	1
GO:0019763	immunoglobulin receptor activity	1/2914	14/18639	0.0714285714285714	0.456883027747818	0.907538802148962	1
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/2914	14/18639	0.0714285714285714	0.456883027747818	0.907538802148962	1
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	1/2914	14/18639	0.0714285714285714	0.456883027747818	0.907538802148962	1
GO:0046030	inositol trisphosphate phosphatase activity	1/2914	14/18639	0.0714285714285714	0.456883027747818	0.907538802148962	1
GO:0098847	sequence-specific single stranded DNA binding	1/2914	14/18639	0.0714285714285714	0.456883027747818	0.907538802148962	1
GO:1990825	sequence-specific mRNA binding	1/2914	14/18639	0.0714285714285714	0.456883027747818	0.907538802148962	1
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	3/2914	33/18639	0.0909090909090909	0.58148748986086	0.907780074470911	1
GO:0019239	deaminase activity	3/2914	33/18639	0.0909090909090909	0.58148748986086	0.907780074470911	1
GO:0004806	triacylglycerol lipase activity	2/2914	24/18639	0.0833333333333333	0.533030199039122	0.90804997770988	1
GO:0019957	C-C chemokine binding	2/2914	24/18639	0.0833333333333333	0.533030199039122	0.90804997770988	1
GO:0042625	ATPase-coupled ion transmembrane transporter activity	2/2914	24/18639	0.0833333333333333	0.533030199039122	0.90804997770988	1
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	2/2914	24/18639	0.0833333333333333	0.533030199039122	0.90804997770988	1
GO:0046961	proton-transporting ATPase activity, rotational mechanism	2/2914	24/18639	0.0833333333333333	0.533030199039122	0.90804997770988	1
GO:0004402	histone acetyltransferase activity	4/2914	42/18639	0.0952380952380952	0.609177370330425	0.91194638550566	1
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	29/2914	229/18639	0.126637554585153	0.810019691116219	0.912365566395567	1
GO:0008170	N-methyltransferase activity	11/2914	98/18639	0.112244897959184	0.717959043603715	0.915689897861319	1
GO:0008173	RNA methyltransferase activity	7/2914	67/18639	0.104477611940299	0.668276667452033	0.916167471839838	1
GO:0015108	chloride transmembrane transporter activity	14/2914	121/18639	0.115702479338843	0.74007498709564	0.917742622854873	1
GO:0052866	phosphatidylinositol phosphate phosphatase activity	3/2914	34/18639	0.0882352941176471	0.564384916629658	0.918151190866128	1
GO:0005244	voltage-gated monoatomic ion channel activity	21/2914	173/18639	0.121387283236994	0.776437052935599	0.919543081939191	1
GO:0005216	monoatomic ion channel activity	60/2914	448/18639	0.133928571428571	0.85665567702716	0.919638841581161	1
GO:0001848	complement binding	2/2914	25/18639	0.08	0.511708991077557	0.919800672763777	1
GO:0019706	protein-cysteine S-palmitoyltransferase activity	2/2914	25/18639	0.08	0.511708991077557	0.919800672763777	1
GO:0019707	protein-cysteine S-acyltransferase activity	2/2914	25/18639	0.08	0.511708991077557	0.919800672763777	1
GO:0008020	G protein-coupled photoreceptor activity	1/2914	15/18639	0.0666666666666667	0.426424159231297	0.922004946070461	1
GO:0008252	nucleotidase activity	1/2914	15/18639	0.0666666666666667	0.426424159231297	0.922004946070461	1
GO:0015250	water channel activity	1/2914	15/18639	0.0666666666666667	0.426424159231297	0.922004946070461	1
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/2914	15/18639	0.0666666666666667	0.426424159231297	0.922004946070461	1
GO:0017081	chloride channel regulator activity	1/2914	15/18639	0.0666666666666667	0.426424159231297	0.922004946070461	1
GO:0045504	dynein heavy chain binding	1/2914	15/18639	0.0666666666666667	0.426424159231297	0.922004946070461	1
GO:0050700	CARD domain binding	1/2914	15/18639	0.0666666666666667	0.426424159231297	0.922004946070461	1
GO:0050780	dopamine receptor binding	1/2914	15/18639	0.0666666666666667	0.426424159231297	0.922004946070461	1
GO:0140223	general transcription initiation factor activity	7/2914	68/18639	0.102941176470588	0.658449069401268	0.923299865641743	1
GO:0016298	lipase activity	15/2914	130/18639	0.115384615384615	0.738041814054168	0.925701987342998	1
GO:0003735	structural constituent of ribosome	21/2914	175/18639	0.12	0.767563486616335	0.928390899910416	1
GO:0022832	voltage-gated channel activity	21/2914	175/18639	0.12	0.767563486616335	0.928390899910416	1
GO:0008080	N-acetyltransferase activity	7/2914	69/18639	0.101449275362319	0.648906329265017	0.929897981263295	1
GO:0008066	glutamate receptor activity	2/2914	26/18639	0.0769230769230769	0.492027876036112	0.930126089438071	1
GO:0008143	poly(A) binding	2/2914	26/18639	0.0769230769230769	0.492027876036112	0.930126089438071	1
GO:0008198	ferrous iron binding	2/2914	26/18639	0.0769230769230769	0.492027876036112	0.930126089438071	1
GO:0019865	immunoglobulin binding	2/2914	26/18639	0.0769230769230769	0.492027876036112	0.930126089438071	1
GO:0005125	cytokine activity	29/2914	234/18639	0.123931623931624	0.792711578058181	0.932016429383991	1
GO:0004252	serine-type endopeptidase activity	21/2914	176/18639	0.119318181818182	0.763202330442379	0.932501340921967	1
GO:0005261	monoatomic cation channel activity	44/2914	341/18639	0.129032258064516	0.825337082383156	0.933017190126488	1
GO:0005506	iron ion binding	18/2914	154/18639	0.116883116883117	0.747626772678248	0.933156550008623	1
GO:0003688	DNA replication origin binding	1/2914	16/18639	0.0625	0.399772649279341	0.934208424761971	1
GO:0008296	3'-5'-DNA exonuclease activity	1/2914	16/18639	0.0625	0.399772649279341	0.934208424761971	1
GO:0016722	oxidoreductase activity, acting on metal ions	1/2914	16/18639	0.0625	0.399772649279341	0.934208424761971	1
GO:0022841	potassium ion leak channel activity	1/2914	16/18639	0.0625	0.399772649279341	0.934208424761971	1
GO:0022858	alanine transmembrane transporter activity	1/2914	16/18639	0.0625	0.399772649279341	0.934208424761971	1
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/2914	16/18639	0.0625	0.399772649279341	0.934208424761971	1
GO:0004620	phospholipase activity	12/2914	109/18639	0.110091743119266	0.704186684969115	0.934276195229542	1
GO:0008266	poly(U) RNA binding	2/2914	27/18639	0.0740740740740741	0.473804621368108	0.939184497104284	1
GO:0016741	transferase activity, transferring one-carbon groups	26/2914	215/18639	0.12093023255814	0.773513591163748	0.941275998555776	1
GO:0008236	serine-type peptidase activity	23/2914	194/18639	0.118556701030928	0.758331623375245	0.944450105169687	1
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/2914	17/18639	0.0588235294117647	0.376256611086439	0.944503041646663	1
GO:0045236	CXCR chemokine receptor binding	1/2914	17/18639	0.0588235294117647	0.376256611086439	0.944503041646663	1
GO:0070402	NADPH binding	1/2914	17/18639	0.0588235294117647	0.376256611086439	0.944503041646663	1
GO:0005242	inward rectifier potassium channel activity	2/2914	28/18639	0.0714285714285714	0.456883027747818	0.947119532833316	1
GO:0036408	histone H3K14 acetyltransferase activity	2/2914	28/18639	0.0714285714285714	0.456883027747818	0.947119532833316	1
GO:0141052	histone H3 demethylase activity	2/2914	28/18639	0.0714285714285714	0.456883027747818	0.947119532833316	1
GO:0003727	single-stranded RNA binding	9/2914	89/18639	0.101123595505618	0.646823162878934	0.950376424806954	1
GO:0099094	ligand-gated monoatomic cation channel activity	15/2914	136/18639	0.110294117647059	0.705481145787073	0.950908622876673	1
GO:0000400	four-way junction DNA binding	1/2914	18/18639	0.0555555555555556	0.355353466026081	0.953187293426365	1
GO:0000900	mRNA regulatory element binding translation repressor activity	1/2914	18/18639	0.0555555555555556	0.355353466026081	0.953187293426365	1
GO:0004970	glutamate-gated receptor activity	1/2914	18/18639	0.0555555555555556	0.355353466026081	0.953187293426365	1
GO:0005372	water transmembrane transporter activity	1/2914	18/18639	0.0555555555555556	0.355353466026081	0.953187293426365	1
GO:0017075	syntaxin-1 binding	1/2914	18/18639	0.0555555555555556	0.355353466026081	0.953187293426365	1
GO:0032393	MHC class I receptor activity	1/2914	18/18639	0.0555555555555556	0.355353466026081	0.953187293426365	1
GO:0004181	metallocarboxypeptidase activity	2/2914	29/18639	0.0689655172413793	0.441128440584101	0.954060906663373	1
GO:0010484	histone H3 acetyltransferase activity	2/2914	29/18639	0.0689655172413793	0.441128440584101	0.954060906663373	1
GO:0000217	DNA secondary structure binding	3/2914	39/18639	0.0769230769230769	0.492027876036112	0.955709552467331	1
GO:0017171	serine hydrolase activity	23/2914	198/18639	0.116161616161616	0.743011792599988	0.956313084663437	1
GO:0008187	poly-pyrimidine tract binding	2/2914	30/18639	0.0666666666666667	0.426424159231297	0.96012524401108	1
GO:0032452	histone demethylase activity	2/2914	30/18639	0.0666666666666667	0.426424159231297	0.96012524401108	1
GO:0043995	histone H4K5 acetyltransferase activity	2/2914	30/18639	0.0666666666666667	0.426424159231297	0.96012524401108	1
GO:0043996	histone H4K8 acetyltransferase activity	2/2914	30/18639	0.0666666666666667	0.426424159231297	0.96012524401108	1
GO:0043997	histone H4K12 acetyltransferase activity	2/2914	30/18639	0.0666666666666667	0.426424159231297	0.96012524401108	1
GO:0008381	mechanosensitive monoatomic ion channel activity	1/2914	19/18639	0.0526315789473684	0.336650652024708	0.960513013149021	1
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	1/2914	19/18639	0.0526315789473684	0.336650652024708	0.960513013149021	1
GO:0034987	immunoglobulin receptor binding	1/2914	19/18639	0.0526315789473684	0.336650652024708	0.960513013149021	1
GO:0032451	demethylase activity	3/2914	40/18639	0.075	0.479727179135209	0.960952417490752	1
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	6/2914	67/18639	0.0895522388059701	0.572808572101743	0.96171864711115	1
GO:0140375	immune receptor activity	17/2914	156/18639	0.108974358974359	0.697039491051159	0.964749474626948	1
GO:0030627	pre-mRNA 5'-splice site binding	1/2914	20/18639	0.05	0.319818119423473	0.96669266297092	1
GO:0052745	inositol phosphate phosphatase activity	1/2914	20/18639	0.05	0.319818119423473	0.96669266297092	1
GO:0140664	ATP-dependent DNA damage sensor activity	1/2914	20/18639	0.05	0.319818119423473	0.96669266297092	1
GO:0140939	histone H4 methyltransferase activity	1/2914	20/18639	0.05	0.319818119423473	0.96669266297092	1
GO:0005272	sodium channel activity	4/2914	51/18639	0.0784313725490196	0.501675481448585	0.968116199886467	1
GO:0048487	beta-tubulin binding	3/2914	42/18639	0.0714285714285714	0.456883027747818	0.969735228112759	1
GO:0070717	poly-purine tract binding	2/2914	32/18639	0.0625	0.399772649279341	0.970029436995177	1
GO:1904047	S-adenosyl-L-methionine binding	1/2914	21/18639	0.0476190476190476	0.304588685165212	0.971905487510516	1
GO:0015079	potassium ion transmembrane transporter activity	17/2914	160/18639	0.10625	0.67961350377488	0.973548386596904	1
GO:0000049	tRNA binding	7/2914	80/18639	0.0875	0.559681708991077	0.975505837647028	1
GO:0001664	G protein-coupled receptor binding	35/2914	297/18639	0.117845117845118	0.753780079449263	0.976014913409317	1
GO:0005243	gap junction channel activity	1/2914	22/18639	0.0454545454545455	0.29074374493043	0.976302705761368	1
GO:0008970	phospholipase A1 activity	1/2914	22/18639	0.0454545454545455	0.29074374493043	0.976302705761368	1
GO:0015377	chloride:monoatomic cation symporter activity	1/2914	22/18639	0.0454545454545455	0.29074374493043	0.976302705761368	1
GO:0032931	histone H3K56 acetyltransferase activity	1/2914	22/18639	0.0454545454545455	0.29074374493043	0.976302705761368	1
GO:0043992	histone H3K9 acetyltransferase activity	1/2914	22/18639	0.0454545454545455	0.29074374493043	0.976302705761368	1
GO:0043993	histone H3K18 acetyltransferase activity	1/2914	22/18639	0.0454545454545455	0.29074374493043	0.976302705761368	1
GO:0043994	histone H3K23 acetyltransferase activity	1/2914	22/18639	0.0454545454545455	0.29074374493043	0.976302705761368	1
GO:0043999	histone H2AK5 acetyltransferase activity	1/2914	22/18639	0.0454545454545455	0.29074374493043	0.976302705761368	1
GO:0044012	histone H2AK9 acetyltransferase activity	1/2914	22/18639	0.0454545454545455	0.29074374493043	0.976302705761368	1
GO:0044014	histone H2BK5 acetyltransferase activity	1/2914	22/18639	0.0454545454545455	0.29074374493043	0.976302705761368	1
GO:0044015	histone H2BK12 acetyltransferase activity	1/2914	22/18639	0.0454545454545455	0.29074374493043	0.976302705761368	1
GO:0044016	histone H3K4 acetyltransferase activity	1/2914	22/18639	0.0454545454545455	0.29074374493043	0.976302705761368	1
GO:0044017	histone H3K27 acetyltransferase activity	1/2914	22/18639	0.0454545454545455	0.29074374493043	0.976302705761368	1
GO:0044018	histone H3K36 acetyltransferase activity	1/2914	22/18639	0.0454545454545455	0.29074374493043	0.976302705761368	1
GO:0046972	histone H4K16 acetyltransferase activity	1/2914	22/18639	0.0454545454545455	0.29074374493043	0.976302705761368	1
GO:0140784	metal ion sensor activity	1/2914	22/18639	0.0454545454545455	0.29074374493043	0.976302705761368	1
GO:0140908	histone H3K122 acetyltransferase activity	1/2914	22/18639	0.0454545454545455	0.29074374493043	0.976302705761368	1
GO:0005249	voltage-gated potassium channel activity	9/2914	98/18639	0.0918367346938776	0.587421035675767	0.977846874542467	1
GO:0015276	ligand-gated monoatomic ion channel activity	20/2914	186/18639	0.10752688172043	0.687780901985963	0.97832999824854	1
GO:0016917	GABA receptor activity	1/2914	23/18639	0.0434782608695652	0.27810271254215	0.980011891742534	1
GO:0044013	histone H2B acetyltransferase activity	1/2914	23/18639	0.0434782608695652	0.27810271254215	0.980011891742534	1
GO:0010485	histone H4 acetyltransferase activity	2/2914	35/18639	0.0571428571428571	0.365506422198255	0.98057483209285	1
GO:0022834	ligand-gated channel activity	20/2914	188/18639	0.106382978723404	0.68046408387973	0.981183226037165	1
GO:0020037	heme binding	14/2914	142/18639	0.0985915492957746	0.630627277736425	0.982973289689086	1
GO:0022836	gated channel activity	37/2914	318/18639	0.116352201257862	0.744230843941415	0.983123622541659	1
GO:0043998	histone H2A acetyltransferase activity	1/2914	24/18639	0.0416666666666667	0.266515099519561	0.983140670613519	1
GO:0030280	structural constituent of skin epidermis	2/2914	37/18639	0.0540540540540541	0.345749318295646	0.985497787880511	1
GO:0016410	N-acyltransferase activity	8/2914	94/18639	0.0851063829787234	0.544371267103784	0.985678338996788	1
GO:0005537	D-mannose binding	1/2914	25/18639	0.04	0.255854495538778	0.985779837190591	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	1/2914	25/18639	0.04	0.255854495538778	0.985779837190591	1
GO:0008188	neuropeptide receptor activity	3/2914	48/18639	0.0625	0.399772649279341	0.986187865120353	1
GO:0001637	G protein-coupled chemoattractant receptor activity	1/2914	26/18639	0.0384615384615385	0.246013938018056	0.988005987100692	1
GO:0004950	chemokine receptor activity	1/2914	26/18639	0.0384615384615385	0.246013938018056	0.988005987100692	1
GO:0004497	monooxygenase activity	9/2914	106/18639	0.0849056603773585	0.543087372605897	0.989707162685736	1
GO:0008395	steroid hydroxylase activity	1/2914	27/18639	0.037037037037037	0.236902310684054	0.989883736715939	1
GO:0005179	hormone activity	12/2914	132/18639	0.0909090909090909	0.58148748986086	0.990170212456803	1
GO:0005267	potassium channel activity	11/2914	124/18639	0.0887096774193548	0.56741924413842	0.990536187812772	1
GO:0004812	aminoacyl-tRNA ligase activity	2/2914	41/18639	0.0487804878048781	0.312017677486315	0.991970211068385	1
GO:0008227	G protein-coupled amine receptor activity	2/2914	41/18639	0.0487804878048781	0.312017677486315	0.991970211068385	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	2/2914	41/18639	0.0487804878048781	0.312017677486315	0.991970211068385	1
GO:0046906	tetrapyrrole binding	14/2914	152/18639	0.0921052631578947	0.58913864104324	0.992686474428063	1
GO:0004629	phospholipase C activity	1/2914	29/18639	0.0344827586206897	0.22056422029205	0.992803549313843	1
GO:0005184	neuropeptide hormone activity	1/2914	31/18639	0.032258064516129	0.206334270595789	0.994880833504124	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	3/2914	56/18639	0.0535714285714286	0.342662270810864	0.9953302134544	1
GO:0031369	translation initiation factor binding	1/2914	32/18639	0.03125	0.199886324639671	0.995682491456025	1
GO:0160041	neuropeptide activity	1/2914	32/18639	0.03125	0.199886324639671	0.995682491456025	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	2/2914	46/18639	0.0434782608695652	0.27810271254215	0.99620511514397	1
GO:0042923	neuropeptide binding	1/2914	33/18639	0.0303030303030303	0.193829163286953	0.996358646660902	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/2914	36/18639	0.0277777777777778	0.17767673301304	0.997815632700504	1
GO:0008528	G protein-coupled peptide receptor activity	9/2914	122/18639	0.0737704918032787	0.471862799149386	0.99802390457171	1
GO:0019843	rRNA binding	3/2914	65/18639	0.0461538461538462	0.295216725621667	0.998676479755364	1
GO:0071855	neuropeptide receptor binding	1/2914	40/18639	0.025	0.159909059711736	0.998895034408814	1
GO:0001653	peptide receptor activity	9/2914	128/18639	0.0703125	0.449744230439259	0.998971907728961	1
GO:0098960	postsynaptic neurotransmitter receptor activity	3/2914	69/18639	0.0434782608695652	0.27810271254215	0.999252712104778	1
GO:0030594	neurotransmitter receptor activity	5/2914	97/18639	0.0515463917525773	0.329709401467498	0.999650538442941	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	1/2914	53/18639	0.0188679245283019	0.120686082801311	0.99987951186325	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	2/2914	73/18639	0.0273972602739726	0.175242805163547	0.999942065276935	1
GO:0022824	transmitter-gated monoatomic ion channel activity	1/2914	63/18639	0.0158730158730159	0.101529561721737	0.999978115652407	1
GO:0022835	transmitter-gated channel activity	1/2914	63/18639	0.0158730158730159	0.101529561721737	0.999978115652407	1
GO:0003823	antigen binding	8/2914	174/18639	0.0459770114942529	0.294085627056067	0.999998938029244	1
GO:0003730	mRNA 3'-UTR binding	16/2914	262/18639	0.0610687022900763	0.390617550440883	0.999999425354413	1
GO:0030371	translation repressor activity	4/2914	329/18639	0.0121580547112462	0.0777673238719691	1	1
GO:0045182	translation regulator activity	7/2914	356/18639	0.0196629213483146	0.125771170559793	1	1