ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 46/1382 175/18639 0.262857142857143 3.54514781889601 1.75369596839322e-14 2.06585385076721e-11 GO:0030695 GTPase regulator activity 81/1382 489/18639 0.165644171779141 2.23403886960305 5.19232635904748e-12 2.27100603150228e-09 GO:0060589 nucleoside-triphosphatase regulator activity 81/1382 490/18639 0.16530612244898 2.22947960660386 5.78354676953042e-12 2.27100603150228e-09 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 23/1382 68/18639 0.338235294117647 4.56177109049119 2.67668550786352e-10 7.88283882065807e-08 GO:0005096 GTPase activator activity 49/1382 271/18639 0.180811808118081 2.43860440775175 4.72968757651674e-09 1.11431439302734e-06 GO:0008137 NADH dehydrogenase (ubiquinone) activity 16/1382 41/18639 0.390243902439024 5.26320991140447 1.33338687630737e-08 2.61788290048347e-06 GO:0015078 proton transmembrane transporter activity 37/1382 185/18639 0.2 2.69739507959479 2.39106927383299e-08 3.52399393918443e-06 GO:0051015 actin filament binding 40/1382 209/18639 0.191387559808612 2.58123931061702 2.39320471251914e-08 3.52399393918443e-06 GO:0003954 NADH dehydrogenase activity 16/1382 44/18639 0.363636363636364 4.90435469017235 4.35528957780594e-08 5.70059013628377e-06 GO:0009055 electron transfer activity 27/1382 116/18639 0.232758620689655 3.13920979090773 7.24187937857899e-08 8.53093390796605e-06 GO:0005085 guanyl-nucleotide exchange factor activity 39/1382 230/18639 0.169565217391304 2.28692191530863 9.53398636608935e-07 0.000102100326720484 GO:0022853 active monoatomic ion transmembrane transporter activity 25/1382 118/18639 0.211864406779661 2.85741004194363 1.43615440954461e-06 0.000140982491203629 GO:0022804 active transmembrane transporter activity 62/1382 457/18639 0.135667396061269 1.82974283298553 2.63250833702091e-06 0.000238545755462356 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 16/1382 58/18639 0.275862068965517 3.72054493737212 3.09677909269326e-06 0.000260571840799475 GO:0031267 small GTPase binding 43/1382 283/18639 0.151943462897526 2.04925774598191 5.35593605694196e-06 0.000420619511671842 GO:0003779 actin binding 58/1382 443/18639 0.130925507900677 1.76578910402368 1.62180468258047e-05 0.00119405369754987 GO:0140375 immune receptor activity 27/1382 156/18639 0.173076923076923 2.33428420349549 2.9546595038097e-05 0.0020474052326399 GO:0051020 GTPase binding 44/1382 315/18639 0.13968253968254 1.88389497622493 3.57279421500687e-05 0.0023381953251545 GO:0050700 CARD domain binding 7/1382 15/18639 0.466666666666667 6.29392185238784 4.59206083409646e-05 0.00284707771713981 GO:0042578 phosphoric ester hydrolase activity 48/1382 363/18639 0.132231404958678 1.78340170551722 6.62170611746159e-05 0.00378524302239346 GO:0016651 oxidoreductase activity, acting on NAD(P)H 18/1382 88/18639 0.204545454545455 2.75869951322194 6.74788654246713e-05 0.00378524302239346 GO:0015399 primary active transmembrane transporter activity 27/1382 166/18639 0.162650602409639 2.19366467316444 8.97777129230881e-05 0.00480718844651808 GO:0017124 SH3 domain binding 21/1382 115/18639 0.182608695652174 2.46283898571698 9.97438997737471e-05 0.00510862234493366 GO:0001784 phosphotyrosine residue binding 12/1382 47/18639 0.25531914893617 3.44348308033377 0.000120035731573722 0.00589175382474354 GO:0005516 calmodulin binding 31/1382 207/18639 0.14975845410628 2.01978858617001 0.000137739660164823 0.00646360510261689 GO:0051219 phosphoprotein binding 18/1382 93/18639 0.193548387096774 2.61038233509173 0.000142660214488998 0.00646360510261689 GO:0008081 phosphoric diester hydrolase activity 17/1382 87/18639 0.195402298850575 2.63538599730526 0.0001916816199958 0.00836299808722418 GO:0005543 phospholipid binding 59/1382 497/18639 0.118712273641851 1.6010695140452 0.000222351051239451 0.00911818654808611 GO:0030552 cAMP binding 8/1382 24/18639 0.333333333333333 4.49565846599132 0.0002244714854792 0.00911818654808611 GO:0045309 protein phosphorylated amino acid binding 13/1382 59/18639 0.220338983050847 2.97170644362138 0.000313182670587992 0.0122976395317551 GO:0019207 kinase regulator activity 38/1382 287/18639 0.132404181184669 1.78573193422652 0.000355553735529331 0.0135110419501146 GO:0005548 phospholipid transporter activity 14/1382 68/18639 0.205882352941176 2.77673022899464 0.000393645906814739 0.0141448468905617 GO:0004860 protein kinase inhibitor activity 16/1382 84/18639 0.19047619047619 2.56894769485218 0.00039624783309723 0.0141448468905617 GO:0005154 epidermal growth factor receptor binding 9/1382 35/18639 0.257142857142857 3.46807938805044 0.000797142463647791 0.0276186418287382 GO:0019210 kinase inhibitor activity 16/1382 90/18639 0.177777777777778 2.39768451519537 0.000875009615924883 0.0294503236445575 GO:0002020 protease binding 21/1382 136/18639 0.154411764705882 2.08254767174598 0.00104452503681031 0.0335054447433944 GO:0001540 amyloid-beta binding 15/1382 83/18639 0.180722891566265 2.43740519240493 0.00105237814559049 0.0335054447433944 GO:0035091 phosphatidylinositol binding 36/1382 284/18639 0.126760563380282 1.70961659974318 0.00111986220801749 0.0342150506987665 GO:0016208 AMP binding 5/1382 12/18639 0.416666666666667 5.61957308248915 0.00113275634741247 0.0342150506987665 GO:0004674 protein serine/threonine kinase activity 50/1382 433/18639 0.115473441108545 1.55738745935034 0.00119658839823468 0.0352395283280112 GO:0030291 protein serine/threonine kinase inhibitor activity 10/1382 46/18639 0.217391304347826 2.9319511734726 0.00168572278923293 0.0484336937979609 GO:0019902 phosphatase binding 26/1382 190/18639 0.136842105263158 1.84558610709117 0.00178050414780763 0.049938902050414 GO:0019887 protein kinase regulator activity 32/1382 255/18639 0.125490196078431 1.69248318719673 0.00240483718378018 0.06588135354635 GO:0019763 immunoglobulin receptor activity 5/1382 14/18639 0.357142857142857 4.81677692784784 0.00252630477302813 0.0661330449472696 GO:0019992 diacylglycerol binding 5/1382 14/18639 0.357142857142857 4.81677692784784 0.00252630477302813 0.0661330449472696 GO:0120013 lipid transfer activity 12/1382 65/18639 0.184615384615385 2.48990315039519 0.00268330577321378 0.068715960887953 GO:0004713 protein tyrosine kinase activity 20/1382 140/18639 0.142857142857143 1.92671077113914 0.00347664164834504 0.0871379545053288 GO:0004129 cytochrome-c oxidase activity 5/1382 15/18639 0.333333333333333 4.49565846599132 0.0035601528209855 0.0873720838150191 GO:0005178 integrin binding 22/1382 161/18639 0.136645962732919 1.84294073761135 0.00391803098598753 0.0941926632957819 GO:0035173 histone kinase activity 41/1382 360/18639 0.113888888888889 1.53601664254703 0.00402600279611119 0.0948526258763796 GO:0106310 protein serine kinase activity 41/1382 361/18639 0.113573407202216 1.53176174880037 0.00422616993462557 0.0958828329326857 GO:0008093 cytoskeletal anchor activity 6/1382 22/18639 0.272727272727273 3.67826601762926 0.00436189360321931 0.0958828329326857 GO:0005345 purine nucleobase transmembrane transporter activity 4/1382 10/18639 0.4 5.39479015918958 0.00439530813103992 0.0958828329326857 GO:0031720 haptoglobin binding 4/1382 10/18639 0.4 5.39479015918958 0.00439530813103992 0.0958828329326857 GO:0015291 secondary active transmembrane transporter activity 34/1382 287/18639 0.118466898954704 1.59776015167636 0.00455723036708779 0.0976075885896258 GO:0001221 transcription coregulator binding 17/1382 115/18639 0.147826086956522 1.99372679796137 0.00475410606461867 0.1000060168593 GO:0016675 oxidoreductase activity, acting on a heme group of donors 5/1382 16/18639 0.3125 4.21467981186686 0.00486570996741831 0.100558005993312 GO:0030551 cyclic nucleotide binding 8/1382 37/18639 0.216216216216216 2.91610278875112 0.00497412275343801 0.101026148337068 GO:0140303 intramembrane lipid transporter activity 9/1382 45/18639 0.2 2.69739507959479 0.00512437898543855 0.102012574581437 GO:0015294 solute:monoatomic cation symporter activity 17/1382 116/18639 0.146551724137931 1.97653949797894 0.00519588665100696 0.102012574581437 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 6/1382 23/18639 0.260869565217391 3.51834140816712 0.00553681497307161 0.105399880249379 GO:0042826 histone deacetylase binding 18/1382 127/18639 0.141732283464567 1.91153982018528 0.00585959846333973 0.105399880249379 GO:0140996 histone H3 kinase activity 40/1382 357/18639 0.112044817927171 1.51114570285422 0.00587782048666968 0.105399880249379 GO:0000146 microfilament motor activity 8/1382 38/18639 0.210526315789474 2.83936324167873 0.00589931720960815 0.105399880249379 GO:0043531 ADP binding 8/1382 38/18639 0.210526315789474 2.83936324167873 0.00589931720960815 0.105399880249379 GO:0030276 clathrin binding 9/1382 46/18639 0.195652173913043 2.63875605612534 0.00596080887100207 0.105399880249379 GO:0005114 type II transforming growth factor beta receptor binding 4/1382 11/18639 0.363636363636364 4.90435469017235 0.00650484889451767 0.105399880249379 GO:0008526 phosphatidylinositol transfer activity 4/1382 11/18639 0.363636363636364 4.90435469017235 0.00650484889451767 0.105399880249379 GO:0015205 nucleobase transmembrane transporter activity 4/1382 11/18639 0.363636363636364 4.90435469017235 0.00650484889451767 0.105399880249379 GO:0019864 IgG binding 4/1382 11/18639 0.363636363636364 4.90435469017235 0.00650484889451767 0.105399880249379 GO:0034713 type I transforming growth factor beta receptor binding 4/1382 11/18639 0.363636363636364 4.90435469017235 0.00650484889451767 0.105399880249379 GO:1990948 ubiquitin ligase inhibitor activity 4/1382 11/18639 0.363636363636364 4.90435469017235 0.00650484889451767 0.105399880249379 GO:0019209 kinase activator activity 20/1382 148/18639 0.135135135135135 1.82256424296945 0.00653157152648953 0.105399880249379 GO:0035591 signaling adaptor activity 18/1382 129/18639 0.13953488372093 1.88190354390334 0.00689266477194558 0.107370604729778 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 6/1382 24/18639 0.25 3.37174384949349 0.00692713578901795 0.107370604729778 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 6/1382 24/18639 0.25 3.37174384949349 0.00692713578901795 0.107370604729778 GO:0005126 cytokine receptor binding 32/1382 275/18639 0.116363636363636 1.56939350085515 0.0075169354211797 0.114999349690256 GO:0015144 carbohydrate transmembrane transporter activity 8/1382 40/18639 0.2 2.69739507959479 0.00813518838279401 0.121802274873906 GO:0140297 DNA-binding transcription factor binding 51/1382 488/18639 0.104508196721311 1.40949947806695 0.00816840383280017 0.121802274873906 GO:0004706 JUN kinase kinase kinase activity 5/1382 18/18639 0.277777777777778 3.74638205499276 0.00842990264976395 0.122878538333236 GO:0141003 histone H2AX kinase activity 39/1382 354/18639 0.110169491525424 1.48585322181069 0.00848699296368001 0.122878538333236 GO:0004709 MAP kinase kinase kinase activity 6/1382 25/18639 0.24 3.23687409551375 0.00855351455290777 0.122878538333236 GO:0017166 vinculin binding 4/1382 12/18639 0.333333333333333 4.49565846599132 0.00919089516807027 0.128891363190319 GO:0097371 MDM2/MDM4 family protein binding 4/1382 12/18639 0.333333333333333 4.49565846599132 0.00919089516807027 0.128891363190319 GO:0140828 metal cation:monoatomic cation antiporter activity 8/1382 41/18639 0.195121951219512 2.63160495570223 0.00946604142134594 0.131188197580536 GO:0019903 protein phosphatase binding 19/1382 144/18639 0.131944444444444 1.77953147612156 0.010114885393355 0.136619742587703 GO:0004112 cyclic-nucleotide phosphodiesterase activity 6/1382 26/18639 0.230769230769231 3.11237893799399 0.0104362048083562 0.136619742587703 GO:0005160 transforming growth factor beta receptor binding 6/1382 26/18639 0.230769230769231 3.11237893799399 0.0104362048083562 0.136619742587703 GO:0120014 phospholipid transfer activity 6/1382 26/18639 0.230769230769231 3.11237893799399 0.0104362048083562 0.136619742587703 GO:0042277 peptide binding 29/1382 249/18639 0.116465863453815 1.5707722351054 0.0104378411145104 0.136619742587703 GO:0035401 histone H3Y41 kinase activity 16/1382 115/18639 0.139130434782609 1.87644875102246 0.0107449871643673 0.137582553039399 GO:0140801 histone H2AXY142 kinase activity 16/1382 115/18639 0.139130434782609 1.87644875102246 0.0107449871643673 0.137582553039399 GO:0004896 cytokine receptor activity 14/1382 96/18639 0.145833333333333 1.9668505788712 0.0110574618633153 0.140061183601994 GO:0044325 transmembrane transporter binding 18/1382 136/18639 0.132352941176471 1.78504086149655 0.0117233176238635 0.145752209967828 GO:0016791 phosphatase activity 31/1382 273/18639 0.113553113553114 1.53148804885418 0.0117542104812764 0.145752209967828 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 10/1382 60/18639 0.166666666666667 2.24782923299566 0.0121743677484698 0.148367155436973 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 4/1382 13/18639 0.307692307692308 4.14983858399199 0.0125073434902197 0.148367155436973 GO:0045159 myosin II binding 4/1382 13/18639 0.307692307692308 4.14983858399199 0.0125073434902197 0.148367155436973 GO:0005319 lipid transporter activity 22/1382 178/18639 0.123595505617978 1.66692954356981 0.0125257925120637 0.148367155436973 GO:0004683 calcium/calmodulin-dependent protein kinase activity 6/1382 27/18639 0.222222222222222 2.99710564399421 0.012594834926738 0.148367155436973 GO:0097110 scaffold protein binding 11/1382 70/18639 0.157142857142857 2.11938184825305 0.0135125813233977 0.157602186128341 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 13/1382 89/18639 0.146067415730337 1.97000764240069 0.0138547114457003 0.158454855175096 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 13/1382 89/18639 0.146067415730337 1.97000764240069 0.0138547114457003 0.158454855175096 GO:0051019 mitogen-activated protein kinase binding 6/1382 28/18639 0.214285714285714 2.8900661567087 0.0150482032703569 0.168138449545744 GO:0055106 ubiquitin-protein transferase regulator activity 7/1382 36/18639 0.194444444444444 2.62246743849493 0.0151228012440581 0.168138449545744 GO:0140793 histone H2AXY142 phosphatase activity 13/1382 90/18639 0.144444444444444 1.94811866859624 0.0151296058165101 0.168138449545744 GO:0004715 non-membrane spanning protein tyrosine kinase activity 8/1382 45/18639 0.177777777777778 2.39768451519537 0.0164435764324314 0.17349109975061 GO:0004065 arylsulfatase activity 4/1382 14/18639 0.285714285714286 3.85342154227827 0.0164997589770964 0.17349109975061 GO:0005161 platelet-derived growth factor receptor binding 4/1382 14/18639 0.285714285714286 3.85342154227827 0.0164997589770964 0.17349109975061 GO:0005344 oxygen carrier activity 4/1382 14/18639 0.285714285714286 3.85342154227827 0.0164997589770964 0.17349109975061 GO:0046030 inositol trisphosphate phosphatase activity 4/1382 14/18639 0.285714285714286 3.85342154227827 0.0164997589770964 0.17349109975061 GO:0009931 calcium-dependent protein serine/threonine kinase activity 5/1382 21/18639 0.238095238095238 3.21118461856523 0.0166365912140723 0.17349109975061 GO:0046873 metal ion transmembrane transporter activity 46/1382 450/18639 0.102222222222222 1.37866859623734 0.0166421852901688 0.17349109975061 GO:0004857 enzyme inhibitor activity 43/1382 416/18639 0.103365384615385 1.39408639930981 0.01692896469379 0.174932635169163 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 6/1382 29/18639 0.206896551724138 2.79040870302909 0.0178140908947017 0.182478252817031 GO:1901981 phosphatidylinositol phosphate binding 22/1382 185/18639 0.118918918918919 1.60385653381312 0.0189062427153073 0.190536594871413 GO:0140313 molecular sequestering activity 9/1382 55/18639 0.163636363636364 2.20695961057756 0.0189669615928738 0.190536594871413 GO:0015081 sodium ion transmembrane transporter activity 20/1382 164/18639 0.121951219512195 1.6447530973139 0.019086008654352 0.190536594871413 GO:0031386 protein tag activity 4/1382 15/18639 0.266666666666667 3.59652677279305 0.0212050703065913 0.203085957895647 GO:0055105 ubiquitin-protein transferase inhibitor activity 4/1382 15/18639 0.266666666666667 3.59652677279305 0.0212050703065913 0.203085957895647 GO:0061578 K63-linked deubiquitinase activity 4/1382 15/18639 0.266666666666667 3.59652677279305 0.0212050703065913 0.203085957895647 GO:0120283 protein serine/threonine kinase binding 4/1382 15/18639 0.266666666666667 3.59652677279305 0.0212050703065913 0.203085957895647 GO:0141047 molecular tag activity 4/1382 15/18639 0.266666666666667 3.59652677279305 0.0212050703065913 0.203085957895647 GO:0015293 symporter activity 18/1382 146/18639 0.123287671232877 1.66277778879131 0.0228728938857711 0.217292491914825 GO:0017022 myosin binding 11/1382 76/18639 0.144736842105263 1.95206222865412 0.0239270227285351 0.225488262193714 GO:0001217 DNA-binding transcription repressor activity 30/1382 278/18639 0.107913669064748 1.45542899978136 0.0246579095097354 0.230531884146574 GO:0031625 ubiquitin protein ligase binding 32/1382 302/18639 0.105960264900662 1.42908348587803 0.0262442649194449 0.241503807546254 GO:0001222 transcription corepressor binding 8/1382 49/18639 0.163265306122449 2.20195516701616 0.0265283785810922 0.241503807546254 GO:0004708 MAP kinase kinase activity 4/1382 16/18639 0.25 3.37174384949349 0.0266515237529822 0.241503807546254 GO:0015385 sodium:proton antiporter activity 4/1382 16/18639 0.25 3.37174384949349 0.0266515237529822 0.241503807546254 GO:0033218 amide binding 27/1382 247/18639 0.109311740890688 1.47428476010242 0.0275434154519892 0.246811207196784 GO:0120015 sterol transfer activity 6/1382 32/18639 0.1875 2.52880788712012 0.0281460310788337 0.246811207196784 GO:0030295 protein kinase activator activity 17/1382 139/18639 0.122302158273381 1.64948619975221 0.0283447200620127 0.246811207196784 GO:0070851 growth factor receptor binding 17/1382 139/18639 0.122302158273381 1.64948619975221 0.0283447200620127 0.246811207196784 GO:0004725 protein tyrosine phosphatase activity 13/1382 98/18639 0.13265306122449 1.78908857320063 0.0287757029496549 0.246811207196784 GO:0015149 hexose transmembrane transporter activity 5/1382 24/18639 0.208333333333333 2.80978654124457 0.0289133672267879 0.246811207196784 GO:0055056 D-glucose transmembrane transporter activity 5/1382 24/18639 0.208333333333333 2.80978654124457 0.0289133672267879 0.246811207196784 GO:0070300 phosphatidic acid binding 5/1382 24/18639 0.208333333333333 2.80978654124457 0.0289133672267879 0.246811207196784 GO:0140318 protein transporter activity 7/1382 41/18639 0.170731707317073 2.30265433623946 0.0295692953716508 0.250594460056148 GO:0002039 p53 binding 10/1382 69/18639 0.144927536231884 1.9546341156484 0.0302045316016712 0.254149558762633 GO:0046332 SMAD binding 11/1382 79/18639 0.139240506329114 1.8779332832622 0.0309080588661476 0.258224775491645 GO:0008484 sulfuric ester hydrolase activity 4/1382 17/18639 0.235294117647059 3.17340597599387 0.0328588415648204 0.261812334286182 GO:0004862 cAMP-dependent protein kinase inhibitor activity 3/1382 10/18639 0.3 4.04609261939219 0.032893230453612 0.261812334286182 GO:0005131 growth hormone receptor binding 3/1382 10/18639 0.3 4.04609261939219 0.032893230453612 0.261812334286182 GO:0005337 nucleoside transmembrane transporter activity 3/1382 10/18639 0.3 4.04609261939219 0.032893230453612 0.261812334286182 GO:0005381 iron ion transmembrane transporter activity 3/1382 10/18639 0.3 4.04609261939219 0.032893230453612 0.261812334286182 GO:0016427 tRNA (cytidine) methyltransferase activity 3/1382 10/18639 0.3 4.04609261939219 0.032893230453612 0.261812334286182 GO:0030957 Tat protein binding 3/1382 10/18639 0.3 4.04609261939219 0.032893230453612 0.261812334286182 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 5/1382 25/18639 0.2 2.69739507959479 0.034003330395258 0.268831699366537 GO:0019955 cytokine binding 17/1382 144/18639 0.118055555555556 1.59221237337192 0.0380508847780266 0.29331123895302 GO:0004435 phosphatidylinositol phospholipase C activity 5/1382 26/18639 0.192307692307692 2.59364911499499 0.0396145507730918 0.29331123895302 GO:0004529 DNA exonuclease activity 5/1382 26/18639 0.192307692307692 2.59364911499499 0.0396145507730918 0.29331123895302 GO:0015145 monosaccharide transmembrane transporter activity 5/1382 26/18639 0.192307692307692 2.59364911499499 0.0396145507730918 0.29331123895302 GO:0019865 immunoglobulin binding 5/1382 26/18639 0.192307692307692 2.59364911499499 0.0396145507730918 0.29331123895302 GO:0050750 low-density lipoprotein particle receptor binding 5/1382 26/18639 0.192307692307692 2.59364911499499 0.0396145507730918 0.29331123895302 GO:0051139 metal cation:proton antiporter activity 5/1382 26/18639 0.192307692307692 2.59364911499499 0.0396145507730918 0.29331123895302 GO:0008525 phosphatidylcholine transporter activity 4/1382 18/18639 0.222222222222222 2.99710564399421 0.0398385383976937 0.29331123895302 GO:0017128 phospholipid scramblase activity 4/1382 18/18639 0.222222222222222 2.99710564399421 0.0398385383976937 0.29331123895302 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 4/1382 18/18639 0.222222222222222 2.99710564399421 0.0398385383976937 0.29331123895302 GO:1901611 phosphatidylglycerol binding 4/1382 18/18639 0.222222222222222 2.99710564399421 0.0398385383976937 0.29331123895302 GO:1901505 carbohydrate derivative transmembrane transporter activity 8/1382 53/18639 0.150943396226415 2.03576987139229 0.0402630769327652 0.294595680911786 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 28/1382 268/18639 0.104477611940299 1.40908698187788 0.0416257414645646 0.298256171763816 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 35/1382 349/18639 0.100286532951289 1.35256200266214 0.0421098620384693 0.298256171763816 GO:0005536 D-glucose binding 3/1382 11/18639 0.272727272727273 3.67826601762926 0.0427888735382724 0.298256171763816 GO:0015173 aromatic amino acid transmembrane transporter activity 3/1382 11/18639 0.272727272727273 3.67826601762926 0.0427888735382724 0.298256171763816 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 3/1382 11/18639 0.272727272727273 3.67826601762926 0.0427888735382724 0.298256171763816 GO:0047676 arachidonate-CoA ligase activity 3/1382 11/18639 0.272727272727273 3.67826601762926 0.0427888735382724 0.298256171763816 GO:0048407 platelet-derived growth factor binding 3/1382 11/18639 0.272727272727273 3.67826601762926 0.0427888735382724 0.298256171763816 GO:0140537 transcription regulator activator activity 3/1382 11/18639 0.272727272727273 3.67826601762926 0.0427888735382724 0.298256171763816 GO:0004527 exonuclease activity 11/1382 84/18639 0.130952380952381 1.76615154021087 0.0455734905132112 0.315203834176095 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 5/1382 27/18639 0.185185185185185 2.49758803666184 0.0457553952836267 0.315203834176095 GO:0019789 SUMO transferase activity 5/1382 28/18639 0.178571428571429 2.40838846392392 0.0524308718082506 0.351370713820171 GO:0050698 proteoglycan sulfotransferase activity 5/1382 28/18639 0.178571428571429 2.40838846392392 0.0524308718082506 0.351370713820171 GO:0051119 sugar transmembrane transporter activity 5/1382 28/18639 0.178571428571429 2.40838846392392 0.0524308718082506 0.351370713820171 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 11/1382 86/18639 0.127906976744186 1.72507824857806 0.0525839358746122 0.351370713820171 GO:0016209 antioxidant activity 11/1382 86/18639 0.127906976744186 1.72507824857806 0.0525839358746122 0.351370713820171 GO:0023023 MHC protein complex binding 6/1382 37/18639 0.162162162162162 2.18707709156334 0.0528756901354767 0.351370713820171 GO:0004000 adenosine deaminase activity 3/1382 12/18639 0.25 3.37174384949349 0.0539881996616732 0.351370713820171 GO:0004875 complement receptor activity 3/1382 12/18639 0.25 3.37174384949349 0.0539881996616732 0.351370713820171 GO:0008603 cAMP-dependent protein kinase regulator activity 3/1382 12/18639 0.25 3.37174384949349 0.0539881996616732 0.351370713820171 GO:0035014 phosphatidylinositol 3-kinase regulator activity 3/1382 12/18639 0.25 3.37174384949349 0.0539881996616732 0.351370713820171 GO:0008237 metallopeptidase activity 20/1382 184/18639 0.108695652173913 1.4659755867363 0.0546786057752029 0.3539087780395 GO:0044389 ubiquitin-like protein ligase binding 32/1382 322/18639 0.0993788819875776 1.34032053644462 0.0554316620770732 0.356822393042581 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 4/1382 20/18639 0.2 2.69739507959479 0.0561227893132604 0.357365653032544 GO:0052745 inositol phosphate phosphatase activity 4/1382 20/18639 0.2 2.69739507959479 0.0561227893132604 0.357365653032544 GO:0004629 phospholipase C activity 5/1382 29/18639 0.172413793103448 2.32534058585758 0.05964270116524 0.377737107379853 GO:0004518 nuclease activity 22/1382 209/18639 0.105263157894737 1.41968162083936 0.060844337539999 0.383286789423096 GO:0030145 manganese ion binding 9/1382 68/18639 0.132352941176471 1.78504086149655 0.0629234816072169 0.392993762206443 GO:0008408 3'-5' exonuclease activity 8/1382 58/18639 0.137931034482759 1.86027246868606 0.0631750733236598 0.392993762206443 GO:0004222 metalloendopeptidase activity 13/1382 110/18639 0.118181818181818 1.59391527430601 0.063411915066957 0.392993762206443 GO:0008373 sialyltransferase activity 4/1382 21/18639 0.19047619047619 2.56894769485218 0.0654136594542458 0.392993762206443 GO:0015370 solute:sodium symporter activity 10/1382 79/18639 0.126582278481013 1.70721207569291 0.0663456999965175 0.392993762206443 GO:0008035 high-density lipoprotein particle binding 3/1382 13/18639 0.230769230769231 3.11237893799399 0.0664324565131092 0.392993762206443 GO:0017154 semaphorin receptor activity 3/1382 13/18639 0.230769230769231 3.11237893799399 0.0664324565131092 0.392993762206443 GO:0032396 inhibitory MHC class I receptor activity 3/1382 13/18639 0.230769230769231 3.11237893799399 0.0664324565131092 0.392993762206443 GO:0043560 insulin receptor substrate binding 3/1382 13/18639 0.230769230769231 3.11237893799399 0.0664324565131092 0.392993762206443 GO:0089720 caspase binding 3/1382 13/18639 0.230769230769231 3.11237893799399 0.0664324565131092 0.392993762206443 GO:0008514 organic anion transmembrane transporter activity 27/1382 269/18639 0.100371747211896 1.3537112852985 0.0668234162516541 0.392993762206443 GO:1902936 phosphatidylinositol bisphosphate binding 13/1382 111/18639 0.117117117117117 1.57955567724019 0.0671842467706699 0.392993762206443 GO:0001965 G-protein alpha-subunit binding 5/1382 30/18639 0.166666666666667 2.24782923299566 0.0673894227213086 0.392993762206443 GO:0001968 fibronectin binding 5/1382 30/18639 0.166666666666667 2.24782923299566 0.0673894227213086 0.392993762206443 GO:0031210 phosphatidylcholine binding 5/1382 30/18639 0.166666666666667 2.24782923299566 0.0673894227213086 0.392993762206443 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 8/1382 59/18639 0.135593220338983 1.82874242684393 0.0685631278561435 0.397868791204616 GO:0035403 histone H3T6 kinase activity 25/1382 247/18639 0.101214574898785 1.36507848157631 0.069914479204473 0.4037218456023 GO:0004679 AMP-activated protein kinase activity 25/1382 248/18639 0.100806451612903 1.35957413286028 0.072533113443798 0.416800037252654 GO:0015377 chloride:monoatomic cation symporter activity 4/1382 22/18639 0.181818181818182 2.45217734508617 0.0754507401343593 0.430004212404605 GO:0070325 lipoprotein particle receptor binding 5/1382 31/18639 0.161290322580645 2.17531861257644 0.0756665284551454 0.430004212404605 GO:0015101 organic cation transmembrane transporter activity 10/1382 81/18639 0.123456790123457 1.6650586911079 0.0759260408999642 0.430004212404605 GO:0140789 histone phosphatase activity 15/1382 136/18639 0.110294117647059 1.48753405124713 0.0790525171173233 0.437165814029632 GO:0001530 lipopolysaccharide binding 6/1382 41/18639 0.146341463414634 1.97370371677668 0.0798946358928861 0.437165814029632 GO:0015175 neutral L-amino acid transmembrane transporter activity 6/1382 41/18639 0.146341463414634 1.97370371677668 0.0798946358928861 0.437165814029632 GO:0016530 metallochaperone activity 3/1382 14/18639 0.214285714285714 2.8900661567087 0.0800504649320218 0.437165814029632 GO:0031404 chloride ion binding 3/1382 14/18639 0.214285714285714 2.8900661567087 0.0800504649320218 0.437165814029632 GO:0032036 myosin heavy chain binding 3/1382 14/18639 0.214285714285714 2.8900661567087 0.0800504649320218 0.437165814029632 GO:0034236 protein kinase A catalytic subunit binding 3/1382 14/18639 0.214285714285714 2.8900661567087 0.0800504649320218 0.437165814029632 GO:0015026 coreceptor activity 8/1382 61/18639 0.131147540983607 1.76878365875068 0.0801594361887951 0.437165814029632 GO:0045296 cadherin binding 32/1382 334/18639 0.0958083832335329 1.29216530759032 0.0815538388435168 0.442720839436234 GO:0051059 NF-kappaB binding 5/1382 32/18639 0.15625 2.10733990593343 0.0844666205618699 0.452280359190376 GO:0071813 lipoprotein particle binding 5/1382 32/18639 0.15625 2.10733990593343 0.0844666205618699 0.452280359190376 GO:0071814 protein-lipid complex binding 5/1382 32/18639 0.15625 2.10733990593343 0.0844666205618699 0.452280359190376 GO:0005283 amino acid:sodium symporter activity 4/1382 23/18639 0.173913043478261 2.34556093877808 0.0862123901955046 0.455959221287938 GO:0015179 L-amino acid transmembrane transporter activity 8/1382 62/18639 0.129032258064516 1.74025489006115 0.0863679711782608 0.455959221287938 GO:0008307 structural constituent of muscle 6/1382 42/18639 0.142857142857143 1.92671077113914 0.0876616270967497 0.455959221287938 GO:0048487 beta-tubulin binding 6/1382 42/18639 0.142857142857143 1.92671077113914 0.0876616270967497 0.455959221287938 GO:0030159 signaling receptor complex adaptor activity 7/1382 52/18639 0.134615384615385 1.81555438049649 0.0878432669482218 0.455959221287938 GO:0043539 protein serine/threonine kinase activator activity 9/1382 73/18639 0.123287671232877 1.66277778879131 0.0898018010038361 0.455959221287938 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 24/1382 243/18639 0.0987654320987654 1.33204695288632 0.0920340470355193 0.455959221287938 GO:0019956 chemokine binding 5/1382 33/18639 0.151515151515152 2.04348112090514 0.0937795880010895 0.455959221287938 GO:0071889 14-3-3 protein binding 5/1382 33/18639 0.151515151515152 2.04348112090514 0.0937795880010895 0.455959221287938 GO:0140311 protein sequestering activity 5/1382 33/18639 0.151515151515152 2.04348112090514 0.0937795880010895 0.455959221287938 GO:0140416 transcription regulator inhibitor activity 5/1382 33/18639 0.151515151515152 2.04348112090514 0.0937795880010895 0.455959221287938 GO:0004467 long-chain fatty acid-CoA ligase activity 3/1382 15/18639 0.2 2.69739507959479 0.0947618135883795 0.455959221287938 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 3/1382 15/18639 0.2 2.69739507959479 0.0947618135883795 0.455959221287938 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 3/1382 15/18639 0.2 2.69739507959479 0.0947618135883795 0.455959221287938 GO:0005245 voltage-gated calcium channel activity 6/1382 43/18639 0.13953488372093 1.88190354390334 0.0958258688327937 0.455959221287938 GO:0030215 semaphorin receptor binding 4/1382 24/18639 0.166666666666667 2.24782923299566 0.0976721947892479 0.455959221287938 GO:0048027 mRNA 5'-UTR binding 4/1382 24/18639 0.166666666666667 2.24782923299566 0.0976721947892479 0.455959221287938 GO:0004676 3-phosphoinositide-dependent protein kinase activity 24/1382 245/18639 0.0979591836734694 1.32117310020969 0.0985609255942066 0.455959221287938 GO:0004711 ribosomal protein S6 kinase activity 24/1382 245/18639 0.0979591836734694 1.32117310020969 0.0985609255942066 0.455959221287938 GO:0035175 histone H3S10 kinase activity 24/1382 245/18639 0.0979591836734694 1.32117310020969 0.0985609255942066 0.455959221287938 GO:0035979 histone H2AXS139 kinase activity 24/1382 245/18639 0.0979591836734694 1.32117310020969 0.0985609255942066 0.455959221287938 GO:0044022 histone H3S28 kinase activity 24/1382 245/18639 0.0979591836734694 1.32117310020969 0.0985609255942066 0.455959221287938 GO:0044023 histone H4S1 kinase activity 24/1382 245/18639 0.0979591836734694 1.32117310020969 0.0985609255942066 0.455959221287938 GO:0044024 histone H2AS1 kinase activity 24/1382 245/18639 0.0979591836734694 1.32117310020969 0.0985609255942066 0.455959221287938 GO:0044025 histone H2BS14 kinase activity 24/1382 245/18639 0.0979591836734694 1.32117310020969 0.0985609255942066 0.455959221287938 GO:0072354 histone H3T3 kinase activity 24/1382 245/18639 0.0979591836734694 1.32117310020969 0.0985609255942066 0.455959221287938 GO:0072371 histone H2AS121 kinase activity 24/1382 245/18639 0.0979591836734694 1.32117310020969 0.0985609255942066 0.455959221287938 GO:0072518 Rho-dependent protein serine/threonine kinase activity 24/1382 245/18639 0.0979591836734694 1.32117310020969 0.0985609255942066 0.455959221287938 GO:0140823 histone H2BS36 kinase activity 24/1382 245/18639 0.0979591836734694 1.32117310020969 0.0985609255942066 0.455959221287938 GO:0140855 histone H3S57 kinase activity 24/1382 245/18639 0.0979591836734694 1.32117310020969 0.0985609255942066 0.455959221287938 GO:0140995 histone H2A kinase activity 24/1382 245/18639 0.0979591836734694 1.32117310020969 0.0985609255942066 0.455959221287938 GO:0140997 histone H4 kinase activity 24/1382 245/18639 0.0979591836734694 1.32117310020969 0.0985609255942066 0.455959221287938 GO:0140998 histone H2B kinase activity 24/1382 245/18639 0.0979591836734694 1.32117310020969 0.0985609255942066 0.455959221287938 GO:1990244 histone H2AT120 kinase activity 24/1382 245/18639 0.0979591836734694 1.32117310020969 0.0985609255942066 0.455959221287938 GO:0004721 phosphoprotein phosphatase activity 18/1382 175/18639 0.102857142857143 1.38723175522018 0.0987008501090189 0.455959221287938 GO:0004677 DNA-dependent protein kinase activity 24/1382 246/18639 0.0975609756097561 1.31580247785112 0.101933787091504 0.467229576629538 GO:0140857 histone H3T45 kinase activity 24/1382 246/18639 0.0975609756097561 1.31580247785112 0.101933787091504 0.467229576629538 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 7/1382 54/18639 0.12962962962963 1.74831162566329 0.102644475175323 0.468663533940042 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 5/1382 34/18639 0.147058823529412 1.98337873499617 0.103592797733842 0.471113147317068 GO:0001223 transcription coactivator binding 6/1382 44/18639 0.136363636363636 1.83913300881463 0.104380756748519 0.471113147317068 GO:0043014 alpha-tubulin binding 6/1382 44/18639 0.136363636363636 1.83913300881463 0.104380756748519 0.471113147317068 GO:0035402 histone H3T11 kinase activity 24/1382 247/18639 0.097165991902834 1.31047534231326 0.105379811258718 0.473806937644158 GO:0038024 cargo receptor activity 8/1382 65/18639 0.123076923076923 1.65993543359679 0.106621246916261 0.477565889229487 GO:0032182 ubiquitin-like protein binding 13/1382 120/18639 0.108333333333333 1.46108900144718 0.107743291815414 0.478474032118421 GO:0015271 outward rectifier potassium channel activity 4/1382 25/18639 0.16 2.15791606367583 0.10979959753096 0.478474032118421 GO:0015296 monoatomic anion:monoatomic cation symporter activity 4/1382 25/18639 0.16 2.15791606367583 0.10979959753096 0.478474032118421 GO:0120020 cholesterol transfer activity 4/1382 25/18639 0.16 2.15791606367583 0.10979959753096 0.478474032118421 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 3/1382 16/18639 0.1875 2.52880788712012 0.110479572781163 0.478474032118421 GO:0004707 MAP kinase activity 3/1382 16/18639 0.1875 2.52880788712012 0.110479572781163 0.478474032118421 GO:0005149 interleukin-1 receptor binding 3/1382 16/18639 0.1875 2.52880788712012 0.110479572781163 0.478474032118421 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 3/1382 16/18639 0.1875 2.52880788712012 0.110479572781163 0.478474032118421 GO:0140328 floppase activity 3/1382 16/18639 0.1875 2.52880788712012 0.110479572781163 0.478474032118421 GO:0042605 peptide antigen binding 6/1382 45/18639 0.133333333333333 1.79826338639653 0.11331821727474 0.487868900271595 GO:0000175 3'-5'-RNA exonuclease activity 5/1382 35/18639 0.142857142857143 1.92671077113914 0.113891296752707 0.487868900271595 GO:0005343 organic acid:sodium symporter activity 5/1382 35/18639 0.142857142857143 1.92671077113914 0.113891296752707 0.487868900271595 GO:0004197 cysteine-type endopeptidase activity 10/1382 88/18639 0.113636363636364 1.53261084067886 0.115897020079073 0.494661919033144 GO:0043130 ubiquitin binding 11/1382 100/18639 0.11 1.48356729377713 0.121556683336565 0.51379461500088 GO:0019199 transmembrane receptor protein kinase activity 9/1382 78/18639 0.115384615384615 1.55618946899699 0.122501228936084 0.51379461500088 GO:0008157 protein phosphatase 1 binding 4/1382 26/18639 0.153846153846154 2.07491929199599 0.1225605151233 0.51379461500088 GO:0034237 protein kinase A regulatory subunit binding 4/1382 26/18639 0.153846153846154 2.07491929199599 0.1225605151233 0.51379461500088 GO:0043548 phosphatidylinositol 3-kinase binding 4/1382 26/18639 0.153846153846154 2.07491929199599 0.1225605151233 0.51379461500088 GO:0004869 cysteine-type endopeptidase inhibitor activity 5/1382 36/18639 0.138888888888889 1.87319102749638 0.12465802137476 0.516690058650164 GO:0015297 antiporter activity 14/1382 135/18639 0.103703703703704 1.39864930053063 0.126935618332051 0.516690058650164 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 3/1382 17/18639 0.176470588235294 2.3800544819954 0.127112586613237 0.516690058650164 GO:0008429 phosphatidylethanolamine binding 3/1382 17/18639 0.176470588235294 2.3800544819954 0.127112586613237 0.516690058650164 GO:0015278 intracellularly gated calcium channel activity 3/1382 17/18639 0.176470588235294 2.3800544819954 0.127112586613237 0.516690058650164 GO:0017110 nucleoside diphosphate phosphatase activity 3/1382 17/18639 0.176470588235294 2.3800544819954 0.127112586613237 0.516690058650164 GO:0030169 low-density lipoprotein particle binding 3/1382 17/18639 0.176470588235294 2.3800544819954 0.127112586613237 0.516690058650164 GO:0004601 peroxidase activity 7/1382 57/18639 0.12280701754386 1.65629522431259 0.127198741093844 0.516690058650164 GO:0015932 nucleobase-containing compound transmembrane transporter activity 7/1382 57/18639 0.12280701754386 1.65629522431259 0.127198741093844 0.516690058650164 GO:0015085 calcium ion transmembrane transporter activity 15/1382 147/18639 0.102040816326531 1.3762219793851 0.129332293036095 0.523551344317937 GO:0019838 growth factor binding 14/1382 136/18639 0.102941176470588 1.38836511449732 0.13243040043866 0.532198888142068 GO:0015171 amino acid transmembrane transporter activity 11/1382 102/18639 0.107843137254902 1.45447773899719 0.134282879631607 0.532198888142068 GO:0042805 actinin binding 5/1382 37/18639 0.135135135135135 1.82256424296945 0.135874010630899 0.532198888142068 GO:0004364 glutathione transferase activity 4/1382 27/18639 0.148148148148148 1.99807042932947 0.13591792726933 0.532198888142068 GO:0008320 protein transmembrane transporter activity 4/1382 27/18639 0.148148148148148 1.99807042932947 0.13591792726933 0.532198888142068 GO:0015252 proton channel activity 4/1382 27/18639 0.148148148148148 1.99807042932947 0.13591792726933 0.532198888142068 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 4/1382 27/18639 0.148148148148148 1.99807042932947 0.13591792726933 0.532198888142068 GO:0023026 MHC class II protein complex binding 4/1382 27/18639 0.148148148148148 1.99807042932947 0.13591792726933 0.532198888142068 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 4/1382 27/18639 0.148148148148148 1.99807042932947 0.13591792726933 0.532198888142068 GO:0061980 regulatory RNA binding 7/1382 58/18639 0.120689655172414 1.6277384101003 0.13598630333681 0.532198888142068 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 6/1382 48/18639 0.125 1.68587192474674 0.142325091355448 0.544215366377585 GO:0032266 phosphatidylinositol-3-phosphate binding 6/1382 48/18639 0.125 1.68587192474674 0.142325091355448 0.544215366377585 GO:0038187 pattern recognition receptor activity 6/1382 48/18639 0.125 1.68587192474674 0.142325091355448 0.544215366377585 GO:0008409 5'-3' exonuclease activity 3/1382 18/18639 0.166666666666667 2.24782923299566 0.144567396256345 0.544215366377585 GO:0015172 acidic amino acid transmembrane transporter activity 3/1382 18/18639 0.166666666666667 2.24782923299566 0.144567396256345 0.544215366377585 GO:0032393 MHC class I receptor activity 3/1382 18/18639 0.166666666666667 2.24782923299566 0.144567396256345 0.544215366377585 GO:0034185 apolipoprotein binding 3/1382 18/18639 0.166666666666667 2.24782923299566 0.144567396256345 0.544215366377585 GO:0070064 proline-rich region binding 3/1382 18/18639 0.166666666666667 2.24782923299566 0.144567396256345 0.544215366377585 GO:0001618 virus receptor activity 9/1382 81/18639 0.111111111111111 1.49855282199711 0.144814754513966 0.544215366377585 GO:0030971 receptor tyrosine kinase binding 9/1382 81/18639 0.111111111111111 1.49855282199711 0.144814754513966 0.544215366377585 GO:0001786 phosphatidylserine binding 7/1382 59/18639 0.11864406779661 1.60014962348843 0.14506250003613 0.544215366377585 GO:0004879 nuclear receptor activity 7/1382 59/18639 0.11864406779661 1.60014962348843 0.14506250003613 0.544215366377585 GO:0070888 E-box binding 7/1382 59/18639 0.11864406779661 1.60014962348843 0.14506250003613 0.544215366377585 GO:0016782 transferase activity, transferring sulphur-containing groups 8/1382 70/18639 0.114285714285714 1.54136861691131 0.145616019887641 0.544557687071878 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 5/1382 38/18639 0.131578947368421 1.7746020260492 0.147518620941078 0.549927010976549 GO:0046875 ephrin receptor binding 4/1382 28/18639 0.142857142857143 1.92671077113914 0.149832436512844 0.552423071265656 GO:0051959 dynein light intermediate chain binding 4/1382 28/18639 0.142857142857143 1.92671077113914 0.149832436512844 0.552423071265656 GO:0140272 exogenous protein binding 9/1382 82/18639 0.109756097560976 1.48027778758251 0.152679525672813 0.552423071265656 GO:0004714 transmembrane receptor protein tyrosine kinase activity 7/1382 60/18639 0.116666666666667 1.57348046309696 0.154418474088669 0.552423071265656 GO:0098531 ligand-modulated transcription factor activity 7/1382 60/18639 0.116666666666667 1.57348046309696 0.154418474088669 0.552423071265656 GO:0030165 PDZ domain binding 9/1382 83/18639 0.108433734939759 1.46244311544296 0.16074973350775 0.552423071265656 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 3/1382 19/18639 0.157894736842105 2.12952243125905 0.162749841149197 0.552423071265656 GO:0022840 leak channel activity 3/1382 19/18639 0.157894736842105 2.12952243125905 0.162749841149197 0.552423071265656 GO:0022842 narrow pore channel activity 3/1382 19/18639 0.157894736842105 2.12952243125905 0.162749841149197 0.552423071265656 GO:0042577 lipid phosphatase activity 3/1382 19/18639 0.157894736842105 2.12952243125905 0.162749841149197 0.552423071265656 GO:0042834 peptidoglycan binding 3/1382 19/18639 0.157894736842105 2.12952243125905 0.162749841149197 0.552423071265656 GO:0046624 sphingolipid transporter activity 3/1382 19/18639 0.157894736842105 2.12952243125905 0.162749841149197 0.552423071265656 GO:0005006 epidermal growth factor receptor activity 6/1382 50/18639 0.12 1.61843704775687 0.163369874461256 0.552423071265656 GO:0015605 organophosphate ester transmembrane transporter activity 6/1382 50/18639 0.12 1.61843704775687 0.163369874461256 0.552423071265656 GO:0019905 syntaxin binding 7/1382 61/18639 0.114754098360656 1.54768570140685 0.164044645668282 0.552423071265656 GO:0003785 actin monomer binding 4/1382 29/18639 0.137931034482759 1.86027246868606 0.16426279416846 0.552423071265656 GO:0005416 amino acid:monoatomic cation symporter activity 4/1382 29/18639 0.137931034482759 1.86027246868606 0.16426279416846 0.552423071265656 GO:0035250 UDP-galactosyltransferase activity 4/1382 29/18639 0.137931034482759 1.86027246868606 0.16426279416846 0.552423071265656 GO:0099604 ligand-gated calcium channel activity 4/1382 29/18639 0.137931034482759 1.86027246868606 0.16426279416846 0.552423071265656 GO:0004090 carbonyl reductase (NADPH) activity 2/1382 10/18639 0.2 2.69739507959479 0.166477241340669 0.552423071265656 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 2/1382 10/18639 0.2 2.69739507959479 0.166477241340669 0.552423071265656 GO:0004445 inositol-polyphosphate 5-phosphatase activity 2/1382 10/18639 0.2 2.69739507959479 0.166477241340669 0.552423071265656 GO:0004935 adrenergic receptor activity 2/1382 10/18639 0.2 2.69739507959479 0.166477241340669 0.552423071265656 GO:0005528 FK506 binding 2/1382 10/18639 0.2 2.69739507959479 0.166477241340669 0.552423071265656 GO:0008239 dipeptidyl-peptidase activity 2/1382 10/18639 0.2 2.69739507959479 0.166477241340669 0.552423071265656 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 2/1382 10/18639 0.2 2.69739507959479 0.166477241340669 0.552423071265656 GO:0015658 branched-chain amino acid transmembrane transporter activity 2/1382 10/18639 0.2 2.69739507959479 0.166477241340669 0.552423071265656 GO:0015924 mannosyl-oligosaccharide mannosidase activity 2/1382 10/18639 0.2 2.69739507959479 0.166477241340669 0.552423071265656 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 2/1382 10/18639 0.2 2.69739507959479 0.166477241340669 0.552423071265656 GO:0031419 cobalamin binding 2/1382 10/18639 0.2 2.69739507959479 0.166477241340669 0.552423071265656 GO:0031434 mitogen-activated protein kinase kinase binding 2/1382 10/18639 0.2 2.69739507959479 0.166477241340669 0.552423071265656 GO:0032395 MHC class II receptor activity 2/1382 10/18639 0.2 2.69739507959479 0.166477241340669 0.552423071265656 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 2/1382 10/18639 0.2 2.69739507959479 0.166477241340669 0.552423071265656 GO:0035374 chondroitin sulfate binding 2/1382 10/18639 0.2 2.69739507959479 0.166477241340669 0.552423071265656 GO:0043295 glutathione binding 2/1382 10/18639 0.2 2.69739507959479 0.166477241340669 0.552423071265656 GO:0050308 sugar-phosphatase activity 2/1382 10/18639 0.2 2.69739507959479 0.166477241340669 0.552423071265656 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 2/1382 10/18639 0.2 2.69739507959479 0.166477241340669 0.552423071265656 GO:0070097 delta-catenin binding 2/1382 10/18639 0.2 2.69739507959479 0.166477241340669 0.552423071265656 GO:0070513 death domain binding 2/1382 10/18639 0.2 2.69739507959479 0.166477241340669 0.552423071265656 GO:0004532 RNA exonuclease activity 5/1382 40/18639 0.125 1.68587192474674 0.172003994993446 0.565979625984021 GO:0050997 quaternary ammonium group binding 5/1382 40/18639 0.125 1.68587192474674 0.172003994993446 0.565979625984021 GO:0071949 FAD binding 5/1382 40/18639 0.125 1.68587192474674 0.172003994993446 0.565979625984021 GO:0005262 calcium channel activity 13/1382 131/18639 0.099236641221374 1.33840213873024 0.173331769210178 0.56875995579273 GO:0005021 vascular endothelial growth factor receptor activity 6/1382 51/18639 0.117647058823529 1.58670298799694 0.174362315230884 0.568971765490253 GO:0005048 signal sequence binding 6/1382 51/18639 0.117647058823529 1.58670298799694 0.174362315230884 0.568971765490253 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 4/1382 30/18639 0.133333333333333 1.79826338639653 0.179166389775714 0.579829689988437 GO:0051721 protein phosphatase 2A binding 4/1382 30/18639 0.133333333333333 1.79826338639653 0.179166389775714 0.579829689988437 GO:0098918 structural constituent of synapse 4/1382 30/18639 0.133333333333333 1.79826338639653 0.179166389775714 0.579829689988437 GO:0003684 damaged DNA binding 8/1382 74/18639 0.108108108108108 1.45805139437556 0.181152544240244 0.58279344767463 GO:0016247 channel regulator activity 16/1382 168/18639 0.0952380952380952 1.28447384742609 0.181502721540774 0.58279344767463 GO:0042288 MHC class I protein binding 3/1382 20/18639 0.15 2.02304630969609 0.18156637970848 0.58279344767463 GO:0005507 copper ion binding 7/1382 63/18639 0.111111111111111 1.49855282199711 0.184065983659036 0.583004197507198 GO:1901682 sulfur compound transmembrane transporter activity 7/1382 63/18639 0.111111111111111 1.49855282199711 0.184065983659036 0.583004197507198 GO:0001727 lipid kinase activity 5/1382 41/18639 0.121951219512195 1.6447530973139 0.18479696153519 0.583004197507198 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 5/1382 41/18639 0.121951219512195 1.6447530973139 0.18479696153519 0.583004197507198 GO:0017080 sodium channel regulator activity 5/1382 41/18639 0.121951219512195 1.6447530973139 0.18479696153519 0.583004197507198 GO:0000287 magnesium ion binding 21/1382 230/18639 0.091304347826087 1.23141949285849 0.188864256626641 0.583004197507198 GO:0141108 transporter regulator activity 16/1382 170/18639 0.0941176470588235 1.26936239039755 0.193831038447009 0.583004197507198 GO:0000099 sulfur amino acid transmembrane transporter activity 2/1382 11/18639 0.181818181818182 2.45217734508617 0.193963545296757 0.583004197507198 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 2/1382 11/18639 0.181818181818182 2.45217734508617 0.193963545296757 0.583004197507198 GO:0008046 axon guidance receptor activity 2/1382 11/18639 0.181818181818182 2.45217734508617 0.193963545296757 0.583004197507198 GO:0008172 S-methyltransferase activity 2/1382 11/18639 0.181818181818182 2.45217734508617 0.193963545296757 0.583004197507198 GO:0008432 JUN kinase binding 2/1382 11/18639 0.181818181818182 2.45217734508617 0.193963545296757 0.583004197507198 GO:0019203 carbohydrate phosphatase activity 2/1382 11/18639 0.181818181818182 2.45217734508617 0.193963545296757 0.583004197507198 GO:0032794 GTPase activating protein binding 2/1382 11/18639 0.181818181818182 2.45217734508617 0.193963545296757 0.583004197507198 GO:0035252 UDP-xylosyltransferase activity 2/1382 11/18639 0.181818181818182 2.45217734508617 0.193963545296757 0.583004197507198 GO:0042285 xylosyltransferase activity 2/1382 11/18639 0.181818181818182 2.45217734508617 0.193963545296757 0.583004197507198 GO:0042608 T cell receptor binding 2/1382 11/18639 0.181818181818182 2.45217734508617 0.193963545296757 0.583004197507198 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 2/1382 11/18639 0.181818181818182 2.45217734508617 0.193963545296757 0.583004197507198 GO:0048185 activin binding 2/1382 11/18639 0.181818181818182 2.45217734508617 0.193963545296757 0.583004197507198 GO:0050786 RAGE receptor binding 2/1382 11/18639 0.181818181818182 2.45217734508617 0.193963545296757 0.583004197507198 GO:0050998 nitric-oxide synthase binding 2/1382 11/18639 0.181818181818182 2.45217734508617 0.193963545296757 0.583004197507198 GO:0099508 voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 2/1382 11/18639 0.181818181818182 2.45217734508617 0.193963545296757 0.583004197507198 GO:0140031 phosphorylation-dependent protein binding 2/1382 11/18639 0.181818181818182 2.45217734508617 0.193963545296757 0.583004197507198 GO:1900750 oligopeptide binding 2/1382 11/18639 0.181818181818182 2.45217734508617 0.193963545296757 0.583004197507198 GO:0004536 DNA nuclease activity 7/1382 64/18639 0.109375 1.4751379341534 0.194438883553429 0.583004197507198 GO:0005164 tumor necrosis factor receptor binding 4/1382 31/18639 0.129032258064516 1.74025489006115 0.194499702563946 0.583004197507198 GO:0005246 calcium channel regulator activity 6/1382 53/18639 0.113207547169811 1.52682740354422 0.197208729060325 0.585168470612249 GO:0008146 sulfotransferase activity 6/1382 53/18639 0.113207547169811 1.52682740354422 0.197208729060325 0.585168470612249 GO:0038064 collagen receptor activity 6/1382 53/18639 0.113207547169811 1.52682740354422 0.197208729060325 0.585168470612249 GO:0051018 protein kinase A binding 6/1382 53/18639 0.113207547169811 1.52682740354422 0.197208729060325 0.585168470612249 GO:0035198 miRNA binding 5/1382 42/18639 0.119047619047619 1.60559230928261 0.197923358080926 0.585813356329976 GO:0001846 opsonin binding 3/1382 21/18639 0.142857142857143 1.92671077113914 0.200925166417519 0.588780711541884 GO:0019200 carbohydrate kinase activity 3/1382 21/18639 0.142857142857143 1.92671077113914 0.200925166417519 0.588780711541884 GO:0036122 BMP binding 3/1382 21/18639 0.142857142857143 1.92671077113914 0.200925166417519 0.588780711541884 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 3/1382 21/18639 0.142857142857143 1.92671077113914 0.200925166417519 0.588780711541884 GO:0019843 rRNA binding 7/1382 65/18639 0.107692307692308 1.45244350439719 0.205037563837225 0.599340571216503 GO:0099106 ion channel regulator activity 15/1382 160/18639 0.09375 1.26440394356006 0.207473152810187 0.604240459030097 GO:0005200 structural constituent of cytoskeleton 11/1382 112/18639 0.0982142857142857 1.32461365515816 0.207739716389804 0.604240459030097 GO:0008378 galactosyltransferase activity 4/1382 32/18639 0.125 1.68587192474674 0.210218714278529 0.605471015697083 GO:0022884 macromolecule transmembrane transporter activity 4/1382 32/18639 0.125 1.68587192474674 0.210218714278529 0.605471015697083 GO:0043425 bHLH transcription factor binding 4/1382 32/18639 0.125 1.68587192474674 0.210218714278529 0.605471015697083 GO:0070717 poly-purine tract binding 4/1382 32/18639 0.125 1.68587192474674 0.210218714278529 0.605471015697083 GO:0004712 protein serine/threonine/tyrosine kinase activity 5/1382 43/18639 0.116279069767442 1.56825295325278 0.211357238245154 0.606652547079363 GO:0061133 endopeptidase activator activity 3/1382 22/18639 0.136363636363636 1.83913300881463 0.220736917935913 0.606652547079363 GO:0004859 phospholipase inhibitor activity 2/1382 12/18639 0.166666666666667 2.24782923299566 0.221958614423774 0.606652547079363 GO:0005025 transforming growth factor beta receptor activity, type I 2/1382 12/18639 0.166666666666667 2.24782923299566 0.221958614423774 0.606652547079363 GO:0005026 transforming growth factor beta receptor activity, type II 2/1382 12/18639 0.166666666666667 2.24782923299566 0.221958614423774 0.606652547079363 GO:0005165 neurotrophin receptor binding 2/1382 12/18639 0.166666666666667 2.24782923299566 0.221958614423774 0.606652547079363 GO:0005527 macrolide binding 2/1382 12/18639 0.166666666666667 2.24782923299566 0.221958614423774 0.606652547079363 GO:0008179 adenylate cyclase binding 2/1382 12/18639 0.166666666666667 2.24782923299566 0.221958614423774 0.606652547079363 GO:0015132 prostaglandin transmembrane transporter activity 2/1382 12/18639 0.166666666666667 2.24782923299566 0.221958614423774 0.606652547079363 GO:0015166 polyol transmembrane transporter activity 2/1382 12/18639 0.166666666666667 2.24782923299566 0.221958614423774 0.606652547079363 GO:0015368 calcium:monoatomic cation antiporter activity 2/1382 12/18639 0.166666666666667 2.24782923299566 0.221958614423774 0.606652547079363 GO:0016361 activin receptor activity, type I 2/1382 12/18639 0.166666666666667 2.24782923299566 0.221958614423774 0.606652547079363 GO:0016362 activin receptor activity, type II 2/1382 12/18639 0.166666666666667 2.24782923299566 0.221958614423774 0.606652547079363 GO:0016840 carbon-nitrogen lyase activity 2/1382 12/18639 0.166666666666667 2.24782923299566 0.221958614423774 0.606652547079363 GO:0017002 activin receptor activity 2/1382 12/18639 0.166666666666667 2.24782923299566 0.221958614423774 0.606652547079363 GO:0034452 dynactin binding 2/1382 12/18639 0.166666666666667 2.24782923299566 0.221958614423774 0.606652547079363 GO:0035259 nuclear glucocorticoid receptor binding 2/1382 12/18639 0.166666666666667 2.24782923299566 0.221958614423774 0.606652547079363 GO:0045295 gamma-catenin binding 2/1382 12/18639 0.166666666666667 2.24782923299566 0.221958614423774 0.606652547079363 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 2/1382 12/18639 0.166666666666667 2.24782923299566 0.221958614423774 0.606652547079363 GO:0070679 inositol 1,4,5 trisphosphate binding 2/1382 12/18639 0.166666666666667 2.24782923299566 0.221958614423774 0.606652547079363 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 2/1382 12/18639 0.166666666666667 2.24782923299566 0.221958614423774 0.606652547079363 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 2/1382 12/18639 0.166666666666667 2.24782923299566 0.221958614423774 0.606652547079363 GO:0019239 deaminase activity 4/1382 33/18639 0.121212121212121 1.63478489672412 0.226279283420245 0.617030083030204 GO:0072341 modified amino acid binding 9/1382 91/18639 0.0989010989010989 1.33387668771171 0.231978573591387 0.631110299516523 GO:0046915 transition metal ion transmembrane transporter activity 5/1382 45/18639 0.111111111111111 1.49855282199711 0.239041416082316 0.645028715683467 GO:0016493 C-C chemokine receptor activity 3/1382 23/18639 0.130434782608696 1.75917070408356 0.240915597096974 0.645028715683467 GO:0099186 structural constituent of postsynapse 3/1382 23/18639 0.130434782608696 1.75917070408356 0.240915597096974 0.645028715683467 GO:0043178 alcohol binding 9/1382 92/18639 0.0978260869565217 1.31937802806267 0.24161121454515 0.645028715683467 GO:0008376 acetylgalactosaminyltransferase activity 4/1382 34/18639 0.117647058823529 1.58670298799694 0.242637481511765 0.645028715683467 GO:0016831 carboxy-lyase activity 4/1382 34/18639 0.117647058823529 1.58670298799694 0.242637481511765 0.645028715683467 GO:0019825 oxygen binding 4/1382 34/18639 0.117647058823529 1.58670298799694 0.242637481511765 0.645028715683467 GO:0052866 phosphatidylinositol phosphate phosphatase activity 4/1382 34/18639 0.117647058823529 1.58670298799694 0.242637481511765 0.645028715683467 GO:0003774 cytoskeletal motor activity 14/1382 153/18639 0.0915032679738562 1.23410232399762 0.24441936211236 0.645028715683467 GO:0016504 peptidase activator activity 6/1382 57/18639 0.105263157894737 1.41968162083936 0.245869149232508 0.645028715683467 GO:0002161 aminoacyl-tRNA editing activity 2/1382 13/18639 0.153846153846154 2.07491929199599 0.250236097680258 0.645028715683467 GO:0008253 5'-nucleotidase activity 2/1382 13/18639 0.153846153846154 2.07491929199599 0.250236097680258 0.645028715683467 GO:0019855 calcium channel inhibitor activity 2/1382 13/18639 0.153846153846154 2.07491929199599 0.250236097680258 0.645028715683467 GO:0031994 insulin-like growth factor I binding 2/1382 13/18639 0.153846153846154 2.07491929199599 0.250236097680258 0.645028715683467 GO:0035325 Toll-like receptor binding 2/1382 13/18639 0.153846153846154 2.07491929199599 0.250236097680258 0.645028715683467 GO:0051011 microtubule minus-end binding 2/1382 13/18639 0.153846153846154 2.07491929199599 0.250236097680258 0.645028715683467 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 2/1382 13/18639 0.153846153846154 2.07491929199599 0.250236097680258 0.645028715683467 GO:0061459 L-arginine transmembrane transporter activity 2/1382 13/18639 0.153846153846154 2.07491929199599 0.250236097680258 0.645028715683467 GO:0070123 transforming growth factor beta receptor activity, type III 2/1382 13/18639 0.153846153846154 2.07491929199599 0.250236097680258 0.645028715683467 GO:0071714 icosanoid transmembrane transporter activity 2/1382 13/18639 0.153846153846154 2.07491929199599 0.250236097680258 0.645028715683467 GO:0140333 glycerophospholipid flippase activity 2/1382 13/18639 0.153846153846154 2.07491929199599 0.250236097680258 0.645028715683467 GO:0140410 monoatomic cation:bicarbonate symporter activity 2/1382 13/18639 0.153846153846154 2.07491929199599 0.250236097680258 0.645028715683467 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 2/1382 13/18639 0.153846153846154 2.07491929199599 0.250236097680258 0.645028715683467 GO:1901338 catecholamine binding 2/1382 13/18639 0.153846153846154 2.07491929199599 0.250236097680258 0.645028715683467 GO:0016874 ligase activity 15/1382 167/18639 0.0898203592814371 1.21140497586592 0.256745592572959 0.660363118015166 GO:0000149 SNARE binding 10/1382 106/18639 0.0943396226415094 1.27235616962018 0.260152185923809 0.663587050979109 GO:0008013 beta-catenin binding 10/1382 106/18639 0.0943396226415094 1.27235616962018 0.260152185923809 0.663587050979109 GO:0015295 solute:proton symporter activity 3/1382 24/18639 0.125 1.68587192474674 0.261378940283792 0.663587050979109 GO:0019957 C-C chemokine binding 3/1382 24/18639 0.125 1.68587192474674 0.261378940283792 0.663587050979109 GO:0035035 histone acetyltransferase binding 3/1382 24/18639 0.125 1.68587192474674 0.261378940283792 0.663587050979109 GO:0050431 transforming growth factor beta binding 3/1382 24/18639 0.125 1.68587192474674 0.261378940283792 0.663587050979109 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 8/1382 83/18639 0.0963855421686747 1.2999494359493 0.272439608732418 0.689248047370632 GO:0140299 molecular sensor activity 7/1382 71/18639 0.0985915492957746 1.32970179980025 0.272656697856294 0.689248047370632 GO:0004705 JUN kinase activity 2/1382 14/18639 0.142857142857143 1.92671077113914 0.278600369804964 0.692386573059594 GO:0005313 L-glutamate transmembrane transporter activity 2/1382 14/18639 0.142857142857143 1.92671077113914 0.278600369804964 0.692386573059594 GO:0015386 potassium:proton antiporter activity 2/1382 14/18639 0.142857142857143 1.92671077113914 0.278600369804964 0.692386573059594 GO:0030983 mismatched DNA binding 2/1382 14/18639 0.142857142857143 1.92671077113914 0.278600369804964 0.692386573059594 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 2/1382 14/18639 0.142857142857143 1.92671077113914 0.278600369804964 0.692386573059594 GO:0070742 C2H2 zinc finger domain binding 2/1382 14/18639 0.142857142857143 1.92671077113914 0.278600369804964 0.692386573059594 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 2/1382 14/18639 0.142857142857143 1.92671077113914 0.278600369804964 0.692386573059594 GO:0098821 BMP receptor activity 2/1382 14/18639 0.142857142857143 1.92671077113914 0.278600369804964 0.692386573059594 GO:0003707 nuclear steroid receptor activity 3/1382 25/18639 0.12 1.61843704775687 0.282048850659178 0.695091100578476 GO:0008483 transaminase activity 3/1382 25/18639 0.12 1.61843704775687 0.282048850659178 0.695091100578476 GO:0015645 fatty acid ligase activity 3/1382 25/18639 0.12 1.61843704775687 0.282048850659178 0.695091100578476 GO:0120515 fatty acid-CoA ligase activity 3/1382 25/18639 0.12 1.61843704775687 0.282048850659178 0.695091100578476 GO:0001664 G protein-coupled receptor binding 25/1382 297/18639 0.0841750841750842 1.13526728939175 0.282785594563535 0.695451837987149 GO:0005518 collagen binding 7/1382 72/18639 0.0972222222222222 1.31123371924747 0.28447308289879 0.697892738586204 GO:0004540 RNA nuclease activity 11/1382 121/18639 0.0909090909090909 1.22608867254309 0.285382374892279 0.697892738586204 GO:0140097 catalytic activity, acting on DNA 28/1382 336/18639 0.0833333333333333 1.12391461649783 0.286459794316531 0.697892738586204 GO:0061135 endopeptidase regulator activity 16/1382 184/18639 0.0869565217391304 1.17278046938904 0.289948359237503 0.697892738586204 GO:0019213 deacetylase activity 4/1382 37/18639 0.108108108108108 1.45805139437556 0.293067799447986 0.697892738586204 GO:0043394 proteoglycan binding 4/1382 37/18639 0.108108108108108 1.45805139437556 0.293067799447986 0.697892738586204 GO:0008528 G protein-coupled peptide receptor activity 11/1382 122/18639 0.0901639344262295 1.21603876539109 0.294511132429845 0.697892738586204 GO:0005004 GPI-linked ephrin receptor activity 5/1382 49/18639 0.102040816326531 1.3762219793851 0.296924437511332 0.697892738586204 GO:0005008 hepatocyte growth factor receptor activity 5/1382 49/18639 0.102040816326531 1.3762219793851 0.296924437511332 0.697892738586204 GO:0005009 insulin receptor activity 5/1382 49/18639 0.102040816326531 1.3762219793851 0.296924437511332 0.697892738586204 GO:0005011 macrophage colony-stimulating factor receptor activity 5/1382 49/18639 0.102040816326531 1.3762219793851 0.296924437511332 0.697892738586204 GO:0005018 platelet-derived growth factor alpha-receptor activity 5/1382 49/18639 0.102040816326531 1.3762219793851 0.296924437511332 0.697892738586204 GO:0005020 stem cell factor receptor activity 5/1382 49/18639 0.102040816326531 1.3762219793851 0.296924437511332 0.697892738586204 GO:0008288 boss receptor activity 5/1382 49/18639 0.102040816326531 1.3762219793851 0.296924437511332 0.697892738586204 GO:0036332 placental growth factor receptor activity 5/1382 49/18639 0.102040816326531 1.3762219793851 0.296924437511332 0.697892738586204 GO:0038062 protein tyrosine kinase collagen receptor activity 5/1382 49/18639 0.102040816326531 1.3762219793851 0.296924437511332 0.697892738586204 GO:0060175 brain-derived neurotrophic factor receptor activity 5/1382 49/18639 0.102040816326531 1.3762219793851 0.296924437511332 0.697892738586204 GO:0001637 G protein-coupled chemoattractant receptor activity 3/1382 26/18639 0.115384615384615 1.55618946899699 0.302851677033423 0.697892738586204 GO:0004950 chemokine receptor activity 3/1382 26/18639 0.115384615384615 1.55618946899699 0.302851677033423 0.697892738586204 GO:0005112 Notch binding 3/1382 26/18639 0.115384615384615 1.55618946899699 0.302851677033423 0.697892738586204 GO:0005227 calcium-activated cation channel activity 3/1382 26/18639 0.115384615384615 1.55618946899699 0.302851677033423 0.697892738586204 GO:0050681 nuclear androgen receptor binding 3/1382 26/18639 0.115384615384615 1.55618946899699 0.302851677033423 0.697892738586204 GO:0070412 R-SMAD binding 3/1382 26/18639 0.115384615384615 1.55618946899699 0.302851677033423 0.697892738586204 GO:0097602 cullin family protein binding 3/1382 26/18639 0.115384615384615 1.55618946899699 0.302851677033423 0.697892738586204 GO:0050660 flavin adenine dinucleotide binding 8/1382 86/18639 0.0930232558139535 1.25460236260223 0.305418394516107 0.697892738586204 GO:0004089 carbonate dehydratase activity 2/1382 15/18639 0.133333333333333 1.79826338639653 0.306883224607516 0.697892738586204 GO:0004559 alpha-mannosidase activity 2/1382 15/18639 0.133333333333333 1.79826338639653 0.306883224607516 0.697892738586204 GO:0005402 carbohydrate:monoatomic cation symporter activity 2/1382 15/18639 0.133333333333333 1.79826338639653 0.306883224607516 0.697892738586204 GO:0008252 nucleotidase activity 2/1382 15/18639 0.133333333333333 1.79826338639653 0.306883224607516 0.697892738586204 GO:0010181 FMN binding 2/1382 15/18639 0.133333333333333 1.79826338639653 0.306883224607516 0.697892738586204 GO:0030553 cGMP binding 2/1382 15/18639 0.133333333333333 1.79826338639653 0.306883224607516 0.697892738586204 GO:0031005 filamin binding 2/1382 15/18639 0.133333333333333 1.79826338639653 0.306883224607516 0.697892738586204 GO:0033130 acetylcholine receptor binding 2/1382 15/18639 0.133333333333333 1.79826338639653 0.306883224607516 0.697892738586204 GO:0034483 heparan sulfate sulfotransferase activity 2/1382 15/18639 0.133333333333333 1.79826338639653 0.306883224607516 0.697892738586204 GO:0047372 monoacylglycerol lipase activity 2/1382 15/18639 0.133333333333333 1.79826338639653 0.306883224607516 0.697892738586204 GO:0050780 dopamine receptor binding 2/1382 15/18639 0.133333333333333 1.79826338639653 0.306883224607516 0.697892738586204 GO:0051371 muscle alpha-actinin binding 2/1382 15/18639 0.133333333333333 1.79826338639653 0.306883224607516 0.697892738586204 GO:0140161 monocarboxylate:sodium symporter activity 2/1382 15/18639 0.133333333333333 1.79826338639653 0.306883224607516 0.697892738586204 GO:0140776 protein-containing complex destabilizing activity 2/1382 15/18639 0.133333333333333 1.79826338639653 0.306883224607516 0.697892738586204 GO:0048029 monosaccharide binding 7/1382 74/18639 0.0945945945945946 1.27579497007862 0.308450781982781 0.700106013826042 GO:0005007 fibroblast growth factor receptor activity 5/1382 50/18639 0.1 1.3486975397974 0.311763833405785 0.700873656015294 GO:0005017 platelet-derived growth factor receptor activity 5/1382 50/18639 0.1 1.3486975397974 0.311763833405785 0.700873656015294 GO:0005019 platelet-derived growth factor beta-receptor activity 5/1382 50/18639 0.1 1.3486975397974 0.311763833405785 0.700873656015294 GO:0032813 tumor necrosis factor receptor superfamily binding 5/1382 50/18639 0.1 1.3486975397974 0.311763833405785 0.700873656015294 GO:0048020 CCR chemokine receptor binding 5/1382 50/18639 0.1 1.3486975397974 0.311763833405785 0.700873656015294 GO:0061134 peptidase regulator activity 19/1382 226/18639 0.084070796460177 1.13386076354648 0.317951677643898 0.713423002408594 GO:0046943 carboxylic acid transmembrane transporter activity 16/1382 188/18639 0.0851063829787234 1.14782769344459 0.319919048975438 0.716472699036246 GO:0003725 double-stranded RNA binding 7/1382 75/18639 0.0933333333333333 1.25878437047757 0.320584459322778 0.71660055613327 GO:0001671 ATPase activator activity 3/1382 27/18639 0.111111111111111 1.49855282199711 0.323718395753934 0.716805019169425 GO:0005385 zinc ion transmembrane transporter activity 3/1382 27/18639 0.111111111111111 1.49855282199711 0.323718395753934 0.716805019169425 GO:0008266 poly(U) RNA binding 3/1382 27/18639 0.111111111111111 1.49855282199711 0.323718395753934 0.716805019169425 GO:0016405 CoA-ligase activity 3/1382 27/18639 0.111111111111111 1.49855282199711 0.323718395753934 0.716805019169425 GO:0035255 ionotropic glutamate receptor binding 3/1382 27/18639 0.111111111111111 1.49855282199711 0.323718395753934 0.716805019169425 GO:0005010 insulin-like growth factor receptor activity 5/1382 51/18639 0.0980392156862745 1.32225248999745 0.326698781033491 0.71717450160682 GO:0005030 neurotrophin receptor activity 5/1382 51/18639 0.0980392156862745 1.32225248999745 0.326698781033491 0.71717450160682 GO:0016597 amino acid binding 5/1382 51/18639 0.0980392156862745 1.32225248999745 0.326698781033491 0.71717450160682 GO:0016830 carbon-carbon lyase activity 5/1382 51/18639 0.0980392156862745 1.32225248999745 0.326698781033491 0.71717450160682 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 4/1382 39/18639 0.102564102564103 1.38327952799733 0.327405117082643 0.71717450160682 GO:0005342 organic acid transmembrane transporter activity 16/1382 189/18639 0.0846560846560847 1.14175453104541 0.327538100054728 0.71717450160682 GO:0003924 GTPase activity 27/1382 331/18639 0.081570996978852 1.10014602944198 0.330598945115563 0.718689193849862 GO:0005024 transforming growth factor beta receptor activity 2/1382 16/18639 0.125 1.68587192474674 0.334940889154138 0.718689193849862 GO:0008296 3'-5'-DNA exonuclease activity 2/1382 16/18639 0.125 1.68587192474674 0.334940889154138 0.718689193849862 GO:0015923 mannosidase activity 2/1382 16/18639 0.125 1.68587192474674 0.334940889154138 0.718689193849862 GO:0022841 potassium ion leak channel activity 2/1382 16/18639 0.125 1.68587192474674 0.334940889154138 0.718689193849862 GO:0022858 alanine transmembrane transporter activity 2/1382 16/18639 0.125 1.68587192474674 0.334940889154138 0.718689193849862 GO:0031435 mitogen-activated protein kinase kinase kinase binding 2/1382 16/18639 0.125 1.68587192474674 0.334940889154138 0.718689193849862 GO:0043023 ribosomal large subunit binding 2/1382 16/18639 0.125 1.68587192474674 0.334940889154138 0.718689193849862 GO:0055102 lipase inhibitor activity 2/1382 16/18639 0.125 1.68587192474674 0.334940889154138 0.718689193849862 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 2/1382 16/18639 0.125 1.68587192474674 0.334940889154138 0.718689193849862 GO:0140327 flippase activity 2/1382 16/18639 0.125 1.68587192474674 0.334940889154138 0.718689193849862 GO:0015631 tubulin binding 31/1382 385/18639 0.0805194805194805 1.08596425282388 0.342106026132497 0.727640695565763 GO:0003714 transcription corepressor activity 17/1382 204/18639 0.0833333333333333 1.12391461649783 0.344100402700924 0.727640695565763 GO:0045499 chemorepellent activity 3/1382 28/18639 0.107142857142857 1.44503307835435 0.344584710862864 0.727640695565763 GO:0046625 sphingolipid binding 3/1382 28/18639 0.107142857142857 1.44503307835435 0.344584710862864 0.727640695565763 GO:0051393 alpha-actinin binding 3/1382 28/18639 0.107142857142857 1.44503307835435 0.344584710862864 0.727640695565763 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 3/1382 28/18639 0.107142857142857 1.44503307835435 0.344584710862864 0.727640695565763 GO:0097718 disordered domain specific binding 3/1382 28/18639 0.107142857142857 1.44503307835435 0.344584710862864 0.727640695565763 GO:0015036 disulfide oxidoreductase activity 4/1382 40/18639 0.1 1.3486975397974 0.344671908425888 0.727640695565763 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 4/1382 40/18639 0.1 1.3486975397974 0.344671908425888 0.727640695565763 GO:0001653 peptide receptor activity 11/1382 128/18639 0.0859375 1.15903694826339 0.350724510171789 0.738323028019871 GO:0160215 deacylase activity 6/1382 65/18639 0.0923076923076923 1.2449515751976 0.350985480213181 0.738323028019871 GO:0005003 ephrin receptor activity 5/1382 53/18639 0.0943396226415094 1.27235616962018 0.356755862566738 0.74685885689277 GO:0005005 transmembrane-ephrin receptor activity 5/1382 53/18639 0.0943396226415094 1.27235616962018 0.356755862566738 0.74685885689277 GO:0042169 SH2 domain binding 4/1382 41/18639 0.0975609756097561 1.31580247785112 0.361955686468125 0.74685885689277 GO:0042287 MHC protein binding 4/1382 41/18639 0.0975609756097561 1.31580247785112 0.361955686468125 0.74685885689277 GO:0004549 tRNA-specific ribonuclease activity 2/1382 17/18639 0.117647058823529 1.58670298799694 0.362651329492924 0.74685885689277 GO:0004550 nucleoside diphosphate kinase activity 2/1382 17/18639 0.117647058823529 1.58670298799694 0.362651329492924 0.74685885689277 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 2/1382 17/18639 0.117647058823529 1.58670298799694 0.362651329492924 0.74685885689277 GO:0015347 sodium-independent organic anion transmembrane transporter activity 2/1382 17/18639 0.117647058823529 1.58670298799694 0.362651329492924 0.74685885689277 GO:0019198 transmembrane receptor protein phosphatase activity 2/1382 17/18639 0.117647058823529 1.58670298799694 0.362651329492924 0.74685885689277 GO:0030548 acetylcholine receptor regulator activity 2/1382 17/18639 0.117647058823529 1.58670298799694 0.362651329492924 0.74685885689277 GO:0032183 SUMO binding 2/1382 17/18639 0.117647058823529 1.58670298799694 0.362651329492924 0.74685885689277 GO:0045125 bioactive lipid receptor activity 2/1382 17/18639 0.117647058823529 1.58670298799694 0.362651329492924 0.74685885689277 GO:0043236 laminin binding 3/1382 29/18639 0.103448275862069 1.39520435151455 0.365391085866065 0.748575128956913 GO:0051861 glycolipid binding 3/1382 29/18639 0.103448275862069 1.39520435151455 0.365391085866065 0.748575128956913 GO:0106222 lncRNA binding 3/1382 29/18639 0.103448275862069 1.39520435151455 0.365391085866065 0.748575128956913 GO:1990782 protein tyrosine kinase binding 10/1382 117/18639 0.0854700854700855 1.15273293999777 0.367951101632394 0.752511107157917 GO:0015485 cholesterol binding 5/1382 54/18639 0.0925925925925926 1.24879401833092 0.371830005604574 0.759126077300152 GO:0052689 carboxylic ester hydrolase activity 8/1382 92/18639 0.0869565217391304 1.17278046938904 0.373478977836831 0.761173418497902 GO:0050840 extracellular matrix binding 6/1382 67/18639 0.0895522388059701 1.20778884160961 0.37803707927419 0.766982968156267 GO:0004175 endopeptidase activity 32/1382 405/18639 0.0790123456790123 1.06563756230905 0.379832282294134 0.766982968156267 GO:0008106 alcohol dehydrogenase (NADP+) activity 3/1382 30/18639 0.1 1.3486975397974 0.386082718764993 0.766982968156267 GO:0008187 poly-pyrimidine tract binding 3/1382 30/18639 0.1 1.3486975397974 0.386082718764993 0.766982968156267 GO:0016769 transferase activity, transferring nitrogenous groups 3/1382 30/18639 0.1 1.3486975397974 0.386082718764993 0.766982968156267 GO:0022839 monoatomic ion-gated channel activity 3/1382 30/18639 0.1 1.3486975397974 0.386082718764993 0.766982968156267 GO:0031624 ubiquitin conjugating enzyme binding 3/1382 30/18639 0.1 1.3486975397974 0.386082718764993 0.766982968156267 GO:0048019 receptor antagonist activity 3/1382 30/18639 0.1 1.3486975397974 0.386082718764993 0.766982968156267 GO:0140104 molecular carrier activity 20/1382 249/18639 0.0803212851405622 1.08329119662441 0.388173803805263 0.766982968156267 GO:0008194 UDP-glycosyltransferase activity 12/1382 145/18639 0.0827586206896552 1.11616348121164 0.389669292940895 0.766982968156267 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/1382 18/18639 0.111111111111111 1.49855282199711 0.389911821147497 0.766982968156267 GO:0004970 glutamate-gated receptor activity 2/1382 18/18639 0.111111111111111 1.49855282199711 0.389911821147497 0.766982968156267 GO:0016854 racemase and epimerase activity 2/1382 18/18639 0.111111111111111 1.49855282199711 0.389911821147497 0.766982968156267 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 2/1382 18/18639 0.111111111111111 1.49855282199711 0.389911821147497 0.766982968156267 GO:0017075 syntaxin-1 binding 2/1382 18/18639 0.111111111111111 1.49855282199711 0.389911821147497 0.766982968156267 GO:0030228 lipoprotein particle receptor activity 2/1382 18/18639 0.111111111111111 1.49855282199711 0.389911821147497 0.766982968156267 GO:0035615 clathrin adaptor activity 2/1382 18/18639 0.111111111111111 1.49855282199711 0.389911821147497 0.766982968156267 GO:0099602 neurotransmitter receptor regulator activity 2/1382 18/18639 0.111111111111111 1.49855282199711 0.389911821147497 0.766982968156267 GO:0140658 ATP-dependent chromatin remodeler activity 13/1382 158/18639 0.0822784810126582 1.10968784920039 0.389962510357956 0.766982968156267 GO:1990841 promoter-specific chromatin binding 6/1382 68/18639 0.0882352941176471 1.1900272409977 0.391582952609276 0.766982968156267 GO:0033192 calmodulin-dependent protein phosphatase activity 7/1382 81/18639 0.0864197530864197 1.16554108377553 0.394559998898725 0.766982968156267 GO:0140791 histone H2AXS140 phosphatase activity 7/1382 81/18639 0.0864197530864197 1.16554108377553 0.394559998898725 0.766982968156267 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 7/1382 81/18639 0.0864197530864197 1.16554108377553 0.394559998898725 0.766982968156267 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 7/1382 81/18639 0.0864197530864197 1.16554108377553 0.394559998898725 0.766982968156267 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 7/1382 81/18639 0.0864197530864197 1.16554108377553 0.394559998898725 0.766982968156267 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 7/1382 81/18639 0.0864197530864197 1.16554108377553 0.394559998898725 0.766982968156267 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 7/1382 81/18639 0.0864197530864197 1.16554108377553 0.394559998898725 0.766982968156267 GO:1990439 MAP kinase serine/threonine phosphatase activity 7/1382 81/18639 0.0864197530864197 1.16554108377553 0.394559998898725 0.766982968156267 GO:0030170 pyridoxal phosphate binding 5/1382 56/18639 0.0892857142857143 1.20419423196196 0.401955457563652 0.778788699029576 GO:0170055 lipid transmembrane transporter activity 5/1382 56/18639 0.0892857142857143 1.20419423196196 0.401955457563652 0.778788699029576 GO:0016878 acid-thiol ligase activity 3/1382 31/18639 0.0967741935483871 1.30519116754587 0.40660947050082 0.782139020841177 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 7/1382 82/18639 0.0853658536585366 1.15132716811973 0.406962662304219 0.782139020841177 GO:0033549 MAP kinase phosphatase activity 7/1382 82/18639 0.0853658536585366 1.15132716811973 0.406962662304219 0.782139020841177 GO:0015079 potassium ion transmembrane transporter activity 13/1382 160/18639 0.08125 1.09581675108538 0.407624971468759 0.782139020841177 GO:0004867 serine-type endopeptidase inhibitor activity 8/1382 95/18639 0.0842105263157895 1.13574529667149 0.407988008798441 0.782139020841177 GO:0016829 lyase activity 16/1382 200/18639 0.08 1.07895803183792 0.413532350260685 0.782139020841177 GO:0016248 channel inhibitor activity 4/1382 44/18639 0.0909090909090909 1.22608867254309 0.413575871320991 0.782139020841177 GO:0030547 signaling receptor inhibitor activity 4/1382 44/18639 0.0909090909090909 1.22608867254309 0.413575871320991 0.782139020841177 GO:0004866 endopeptidase inhibitor activity 13/1382 161/18639 0.0807453416149068 1.08901043586125 0.416471594434793 0.782139020841177 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 2/1382 19/18639 0.105263157894737 1.41968162083936 0.416636759970826 0.782139020841177 GO:0005346 purine ribonucleotide transmembrane transporter activity 2/1382 19/18639 0.105263157894737 1.41968162083936 0.416636759970826 0.782139020841177 GO:0005520 insulin-like growth factor binding 2/1382 19/18639 0.105263157894737 1.41968162083936 0.416636759970826 0.782139020841177 GO:0008301 DNA binding, bending 2/1382 19/18639 0.105263157894737 1.41968162083936 0.416636759970826 0.782139020841177 GO:0008381 mechanosensitive monoatomic ion channel activity 2/1382 19/18639 0.105263157894737 1.41968162083936 0.416636759970826 0.782139020841177 GO:0022821 solute:potassium antiporter activity 2/1382 19/18639 0.105263157894737 1.41968162083936 0.416636759970826 0.782139020841177 GO:0031420 alkali metal ion binding 2/1382 19/18639 0.105263157894737 1.41968162083936 0.416636759970826 0.782139020841177 GO:0043395 heparan sulfate proteoglycan binding 2/1382 19/18639 0.105263157894737 1.41968162083936 0.416636759970826 0.782139020841177 GO:0050145 nucleoside monophosphate kinase activity 2/1382 19/18639 0.105263157894737 1.41968162083936 0.416636759970826 0.782139020841177 GO:0097001 ceramide binding 2/1382 19/18639 0.105263157894737 1.41968162083936 0.416636759970826 0.782139020841177 GO:0070279 vitamin B6 binding 5/1382 57/18639 0.087719298245614 1.18306801736614 0.416963756441646 0.782139020841177 GO:0008028 monocarboxylic acid transmembrane transporter activity 6/1382 70/18639 0.0857142857142857 1.15602646268348 0.418634337017448 0.784024243253662 GO:0019001 guanyl nucleotide binding 31/1382 400/18639 0.0775 1.04524059334298 0.425488113249587 0.794334385749624 GO:0032561 guanyl ribonucleotide binding 31/1382 400/18639 0.0775 1.04524059334298 0.425488113249587 0.794334385749624 GO:0008509 monoatomic anion transmembrane transporter activity 12/1382 149/18639 0.0805369127516778 1.08619936091065 0.426577892430094 0.795108793168752 GO:0141110 transporter inhibitor activity 4/1382 45/18639 0.0888888888888889 1.19884225759768 0.430603623051593 0.800889808396791 GO:0017018 myosin phosphatase activity 7/1382 84/18639 0.0833333333333333 1.12391461649783 0.431719039331038 0.800889808396791 GO:0051117 ATPase binding 7/1382 84/18639 0.0833333333333333 1.12391461649783 0.431719039331038 0.800889808396791 GO:0001614 purinergic nucleotide receptor activity 2/1382 20/18639 0.1 1.3486975397974 0.442755691111086 0.814947193951343 GO:0005326 neurotransmitter transmembrane transporter activity 2/1382 20/18639 0.1 1.3486975397974 0.442755691111086 0.814947193951343 GO:0016502 nucleotide receptor activity 2/1382 20/18639 0.1 1.3486975397974 0.442755691111086 0.814947193951343 GO:0016505 peptidase activator activity involved in apoptotic process 2/1382 20/18639 0.1 1.3486975397974 0.442755691111086 0.814947193951343 GO:0030742 GTP-dependent protein binding 2/1382 20/18639 0.1 1.3486975397974 0.442755691111086 0.814947193951343 GO:0042379 chemokine receptor binding 6/1382 72/18639 0.0833333333333333 1.12391461649783 0.445530660845861 0.817631513284012 GO:0015459 potassium channel regulator activity 5/1382 59/18639 0.0847457627118644 1.14296401677745 0.446770987229106 0.817631513284012 GO:0031593 polyubiquitin modification-dependent protein binding 5/1382 59/18639 0.0847457627118644 1.14296401677745 0.446770987229106 0.817631513284012 GO:0030296 protein tyrosine kinase activator activity 3/1382 33/18639 0.0909090909090909 1.22608867254309 0.446990402847966 0.817631513284012 GO:0140101 catalytic activity, acting on a tRNA 11/1382 139/18639 0.079136690647482 1.06731459983967 0.456764667009717 0.834215159282862 GO:0004521 RNA endonuclease activity 6/1382 73/18639 0.0821917808219178 1.10851852586087 0.458884834343319 0.835686650289185 GO:0043495 protein-membrane adaptor activity 4/1382 47/18639 0.0851063829787234 1.14782769344459 0.464226772200203 0.835686650289185 GO:0008175 tRNA methyltransferase activity 3/1382 34/18639 0.0882352941176471 1.1900272409977 0.466766492009533 0.835686650289185 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 3/1382 34/18639 0.0882352941176471 1.1900272409977 0.466766492009533 0.835686650289185 GO:0051427 hormone receptor binding 3/1382 34/18639 0.0882352941176471 1.1900272409977 0.466766492009533 0.835686650289185 GO:0090482 vitamin transmembrane transporter activity 3/1382 34/18639 0.0882352941176471 1.1900272409977 0.466766492009533 0.835686650289185 GO:0005248 voltage-gated sodium channel activity 2/1382 21/18639 0.0952380952380952 1.28447384742609 0.468211535815673 0.835686650289185 GO:0009975 cyclase activity 2/1382 21/18639 0.0952380952380952 1.28447384742609 0.468211535815673 0.835686650289185 GO:0010314 phosphatidylinositol-5-phosphate binding 2/1382 21/18639 0.0952380952380952 1.28447384742609 0.468211535815673 0.835686650289185 GO:0015125 bile acid transmembrane transporter activity 2/1382 21/18639 0.0952380952380952 1.28447384742609 0.468211535815673 0.835686650289185 GO:0015174 basic amino acid transmembrane transporter activity 2/1382 21/18639 0.0952380952380952 1.28447384742609 0.468211535815673 0.835686650289185 GO:0051010 microtubule plus-end binding 2/1382 21/18639 0.0952380952380952 1.28447384742609 0.468211535815673 0.835686650289185 GO:0061891 calcium ion sensor activity 2/1382 21/18639 0.0952380952380952 1.28447384742609 0.468211535815673 0.835686650289185 GO:0072542 protein phosphatase activator activity 2/1382 21/18639 0.0952380952380952 1.28447384742609 0.468211535815673 0.835686650289185 GO:0140312 cargo adaptor activity 2/1382 21/18639 0.0952380952380952 1.28447384742609 0.468211535815673 0.835686650289185 GO:0004519 endonuclease activity 10/1382 127/18639 0.078740157480315 1.0619665667696 0.469525838483709 0.836764656178229 GO:0005261 monoatomic cation channel activity 26/1382 341/18639 0.0762463343108504 1.02833243503614 0.470627325263858 0.837460708702152 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 5/1382 61/18639 0.0819672131147541 1.10548978671918 0.476176479944102 0.844782971949025 GO:0016836 hydro-lyase activity 5/1382 61/18639 0.0819672131147541 1.10548978671918 0.476176479944102 0.844782971949025 GO:0016879 ligase activity, forming carbon-nitrogen bonds 4/1382 48/18639 0.0833333333333333 1.12391461649783 0.480774095926433 0.848169534863957 GO:0043015 gamma-tubulin binding 3/1382 35/18639 0.0857142857142857 1.15602646268348 0.486221173218388 0.848169534863957 GO:0140566 histone reader activity 3/1382 35/18639 0.0857142857142857 1.15602646268348 0.486221173218388 0.848169534863957 GO:0030414 peptidase inhibitor activity 13/1382 169/18639 0.0769230769230769 1.037459645998 0.48703318049802 0.848169534863957 GO:0003727 single-stranded RNA binding 7/1382 89/18639 0.0786516853932584 1.06077334590806 0.492799715406704 0.848169534863957 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 2/1382 22/18639 0.0909090909090909 1.22608867254309 0.492958997603649 0.848169534863957 GO:0016881 acid-amino acid ligase activity 2/1382 22/18639 0.0909090909090909 1.22608867254309 0.492958997603649 0.848169534863957 GO:0031683 G-protein beta/gamma-subunit complex binding 2/1382 22/18639 0.0909090909090909 1.22608867254309 0.492958997603649 0.848169534863957 GO:0140517 protein-RNA adaptor activity 2/1382 22/18639 0.0909090909090909 1.22608867254309 0.492958997603649 0.848169534863957 GO:0140784 metal ion sensor activity 2/1382 22/18639 0.0909090909090909 1.22608867254309 0.492958997603649 0.848169534863957 GO:0016763 pentosyltransferase activity 4/1382 49/18639 0.0816326530612245 1.10097758350808 0.497116287785553 0.848169534863957 GO:0035254 glutamate receptor binding 4/1382 49/18639 0.0816326530612245 1.10097758350808 0.497116287785553 0.848169534863957 GO:0060590 ATPase regulator activity 4/1382 49/18639 0.0816326530612245 1.10097758350808 0.497116287785553 0.848169534863957 GO:0004722 protein serine/threonine phosphatase activity 8/1382 103/18639 0.0776699029126214 1.04753206974555 0.499121204931109 0.848169534863957 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 10/1382 130/18639 0.0769230769230769 1.037459645998 0.499600204354309 0.848169534863957 GO:0004033 aldo-keto reductase (NADPH) activity 3/1382 36/18639 0.0833333333333333 1.12391461649783 0.505325472935275 0.848169534863957 GO:0005484 SNAP receptor activity 3/1382 36/18639 0.0833333333333333 1.12391461649783 0.505325472935275 0.848169534863957 GO:0044390 ubiquitin-like protein conjugating enzyme binding 3/1382 36/18639 0.0833333333333333 1.12391461649783 0.505325472935275 0.848169534863957 GO:0016757 glycosyltransferase activity 20/1382 267/18639 0.0749063670411985 1.01026032943625 0.51485923275222 0.848169534863957 GO:0000295 adenine nucleotide transmembrane transporter activity 2/1382 23/18639 0.0869565217391304 1.17278046938904 0.516963130985237 0.848169534863957 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 2/1382 23/18639 0.0869565217391304 1.17278046938904 0.516963130985237 0.848169534863957 GO:0005158 insulin receptor binding 2/1382 23/18639 0.0869565217391304 1.17278046938904 0.516963130985237 0.848169534863957 GO:0016849 phosphorus-oxygen lyase activity 2/1382 23/18639 0.0869565217391304 1.17278046938904 0.516963130985237 0.848169534863957 GO:0017134 fibroblast growth factor binding 2/1382 23/18639 0.0869565217391304 1.17278046938904 0.516963130985237 0.848169534863957 GO:0031681 G-protein beta-subunit binding 2/1382 23/18639 0.0869565217391304 1.17278046938904 0.516963130985237 0.848169534863957 GO:0043274 phospholipase binding 2/1382 23/18639 0.0869565217391304 1.17278046938904 0.516963130985237 0.848169534863957 GO:0070577 lysine-acetylated histone binding 2/1382 23/18639 0.0869565217391304 1.17278046938904 0.516963130985237 0.848169534863957 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 2/1382 23/18639 0.0869565217391304 1.17278046938904 0.516963130985237 0.848169534863957 GO:0005244 voltage-gated monoatomic ion channel activity 13/1382 173/18639 0.0751445086705202 1.01347213973215 0.521741617296802 0.848169534863957 GO:0022829 wide pore channel activity 3/1382 37/18639 0.0810810810810811 1.09353854578167 0.524054091184154 0.848169534863957 GO:0005539 glycosaminoglycan binding 18/1382 242/18639 0.0743801652892562 1.00316345935343 0.530015140795479 0.848169534863957 GO:0016741 transferase activity, transferring one-carbon groups 16/1382 215/18639 0.0744186046511628 1.00368189008178 0.531571287346103 0.848169534863957 GO:0000182 rDNA binding 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0001094 TFIID-class transcription factor complex binding 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0004382 GDP phosphatase activity 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0004955 prostaglandin receptor activity 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0005031 tumor necrosis factor receptor activity 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0005522 profilin binding 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0008519 ammonium channel activity 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0015203 polyamine transmembrane transporter activity 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0015279 store-operated calcium channel activity 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0016783 sulfurtransferase activity 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0031956 medium-chain fatty acid-CoA ligase activity 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0031996 thioesterase binding 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0032052 bile acid binding 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0042975 peroxisome proliferator activated receptor binding 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0043121 neurotrophin binding 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0043208 glycosphingolipid binding 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0045322 unmethylated CpG binding 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0047429 nucleoside triphosphate diphosphatase activity 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0050815 phosphoserine residue binding 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0051864 histone H3K36 demethylase activity 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0071723 lipopeptide binding 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0099122 RNA polymerase II C-terminal domain binding 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0140135 mechanosensitive monoatomic cation channel activity 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0140940 histone H2A methyltransferase activity 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:1905394 retromer complex binding 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:1990259 histone H2AQ104 methyltransferase activity 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:1990757 ubiquitin ligase activator activity 1/1382 10/18639 0.1 1.3486975397974 0.537253748507913 0.848169534863957 GO:0022832 voltage-gated channel activity 13/1382 175/18639 0.0742857142857143 1.00188960099235 0.538845234327223 0.848169534863957 GO:0001091 RNA polymerase II general transcription initiation factor binding 2/1382 24/18639 0.0833333333333333 1.12391461649783 0.540198057412641 0.848169534863957 GO:0004806 triacylglycerol lipase activity 2/1382 24/18639 0.0833333333333333 1.12391461649783 0.540198057412641 0.848169534863957 GO:0005315 phosphate transmembrane transporter activity 2/1382 24/18639 0.0833333333333333 1.12391461649783 0.540198057412641 0.848169534863957 GO:0005540 hyaluronic acid binding 2/1382 24/18639 0.0833333333333333 1.12391461649783 0.540198057412641 0.848169534863957 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 2/1382 24/18639 0.0833333333333333 1.12391461649783 0.540198057412641 0.848169534863957 GO:0050699 WW domain binding 2/1382 24/18639 0.0833333333333333 1.12391461649783 0.540198057412641 0.848169534863957 GO:0140033 acetylation-dependent protein binding 2/1382 24/18639 0.0833333333333333 1.12391461649783 0.540198057412641 0.848169534863957 GO:0005109 frizzled binding 3/1382 38/18639 0.0789473684210526 1.06476121562952 0.542385193381638 0.848169534863957 GO:0019888 protein phosphatase regulator activity 8/1382 107/18639 0.0747663551401869 1.00837199237188 0.543174840402926 0.848169534863957 GO:0005080 protein kinase C binding 4/1382 52/18639 0.0769230769230769 1.037459645998 0.544726302396945 0.848169534863957 GO:0015108 chloride transmembrane transporter activity 9/1382 121/18639 0.0743801652892562 1.00316345935343 0.545974742616736 0.848169534863957 GO:0004252 serine-type endopeptidase activity 13/1382 176/18639 0.0738636363636364 0.996197046441258 0.547322186931229 0.848169534863957 GO:0042562 hormone binding 7/1382 94/18639 0.074468085106383 1.00434923176402 0.551729540807003 0.848169534863957 GO:0008168 methyltransferase activity 15/1382 204/18639 0.0735294117647059 0.991689367498085 0.552210479626399 0.848169534863957 GO:0004864 protein phosphatase inhibitor activity 4/1382 53/18639 0.0754716981132075 1.01788493569615 0.560070828097369 0.848169534863957 GO:0017046 peptide hormone binding 4/1382 53/18639 0.0754716981132075 1.01788493569615 0.560070828097369 0.848169534863957 GO:0016776 phosphotransferase activity, phosphate group as acceptor 3/1382 39/18639 0.0769230769230769 1.037459645998 0.560300199739888 0.848169534863957 GO:0016500 protein-hormone receptor activity 5/1382 67/18639 0.0746268656716418 1.00649070134134 0.560734217675958 0.848169534863957 GO:0019787 ubiquitin-like protein transferase activity 35/1382 479/18639 0.0730688935281837 0.985478369371792 0.562066488727109 0.848169534863957 GO:0001848 complement binding 2/1382 25/18639 0.08 1.07895803183792 0.562645814521638 0.848169534863957 GO:0005251 delayed rectifier potassium channel activity 2/1382 25/18639 0.08 1.07895803183792 0.562645814521638 0.848169534863957 GO:0008139 nuclear localization sequence binding 2/1382 25/18639 0.08 1.07895803183792 0.562645814521638 0.848169534863957 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 2/1382 25/18639 0.08 1.07895803183792 0.562645814521638 0.848169534863957 GO:0019211 phosphatase activator activity 2/1382 25/18639 0.08 1.07895803183792 0.562645814521638 0.848169534863957 GO:0016922 nuclear receptor binding 10/1382 137/18639 0.072992700729927 0.984450758976201 0.567701249009137 0.848169534863957 GO:0000510 H3-H4 histone complex chaperone activity 11/1382 151/18639 0.0728476821192053 0.982494896541149 0.569273755086148 0.848169534863957 GO:0140584 chromatin extrusion motor activity 11/1382 151/18639 0.0728476821192053 0.982494896541149 0.569273755086148 0.848169534863957 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 11/1382 151/18639 0.0728476821192053 0.982494896541149 0.569273755086148 0.848169534863957 GO:0140849 ATP-dependent H2AZ histone chaperone activity 11/1382 151/18639 0.0728476821192053 0.982494896541149 0.569273755086148 0.848169534863957 GO:0005125 cytokine activity 17/1382 234/18639 0.0726495726495727 0.979822998998108 0.571302724961809 0.848169534863957 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0001851 complement component C3b binding 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0002162 dystroglycan binding 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0003953 NAD+ nucleosidase activity 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0004016 adenylate cyclase activity 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0004954 prostanoid receptor activity 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0005225 volume-sensitive anion channel activity 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0008271 secondary active sulfate transmembrane transporter activity 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0008503 benzodiazepine receptor activity 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0019215 intermediate filament binding 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0031731 CCR6 chemokine receptor binding 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0032050 clathrin heavy chain binding 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0043855 cyclic nucleotide-activated monoatomic ion channel activity 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0045294 alpha-catenin binding 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0070697 activin receptor binding 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0180030 inositol phosphate kinase activity 1/1382 11/18639 0.0909090909090909 1.22608867254309 0.571582768829029 0.848169534863957 GO:0032934 sterol binding 5/1382 68/18639 0.0735294117647059 0.991689367498085 0.574158921252678 0.848169534863957 GO:0051287 NAD binding 4/1382 54/18639 0.0740740740740741 0.999035214664737 0.575130093896793 0.848169534863957 GO:0140463 chromatin-protein adaptor activity 4/1382 54/18639 0.0740740740740741 0.999035214664737 0.575130093896793 0.848169534863957 GO:0008017 microtubule binding 20/1382 276/18639 0.072463768115942 0.977317057824199 0.576280602166154 0.848169534863957 GO:0030331 nuclear estrogen receptor binding 3/1382 40/18639 0.075 1.01152315484805 0.577783574711293 0.848169534863957 GO:0071855 neuropeptide receptor binding 3/1382 40/18639 0.075 1.01152315484805 0.577783574711293 0.848169534863957 GO:0015616 DNA translocase activity 11/1382 152/18639 0.0723684210526316 0.976031114327062 0.578247287361216 0.848169534863957 GO:0046906 tetrapyrrole binding 11/1382 152/18639 0.0723684210526316 0.976031114327062 0.578247287361216 0.848169534863957 GO:0140674 ATP-dependent histone chaperone activity 11/1382 152/18639 0.0723684210526316 0.976031114327062 0.578247287361216 0.848169534863957 GO:0016755 aminoacyltransferase activity 36/1382 496/18639 0.0725806451612903 0.9788933756594 0.578964943323646 0.848169534863957 GO:0008066 glutamate receptor activity 2/1382 26/18639 0.0769230769230769 1.037459645998 0.584295325978989 0.848169534863957 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 2/1382 26/18639 0.0769230769230769 1.037459645998 0.584295325978989 0.848169534863957 GO:0008143 poly(A) binding 2/1382 26/18639 0.0769230769230769 1.037459645998 0.584295325978989 0.848169534863957 GO:0015216 purine nucleotide transmembrane transporter activity 2/1382 26/18639 0.0769230769230769 1.037459645998 0.584295325978989 0.848169534863957 GO:0030247 polysaccharide binding 2/1382 26/18639 0.0769230769230769 1.037459645998 0.584295325978989 0.848169534863957 GO:0052742 phosphatidylinositol kinase activity 2/1382 26/18639 0.0769230769230769 1.037459645998 0.584295325978989 0.848169534863957 GO:0061775 cohesin loader activity 11/1382 153/18639 0.0718954248366013 0.969651825998127 0.587140414667215 0.848169534863957 GO:0008227 G protein-coupled amine receptor activity 3/1382 41/18639 0.0731707317073171 0.986851858388338 0.594822618519965 0.848169534863957 GO:0016877 ligase activity, forming carbon-sulfur bonds 3/1382 41/18639 0.0731707317073171 0.986851858388338 0.594822618519965 0.848169534863957 GO:0061650 ubiquitin-like protein conjugating enzyme activity 3/1382 41/18639 0.0731707317073171 0.986851858388338 0.594822618519965 0.848169534863957 GO:0008094 ATP-dependent activity, acting on DNA 15/1382 210/18639 0.0714285714285714 0.963355385569568 0.598324434351046 0.848169534863957 GO:0030246 carbohydrate binding 20/1382 280/18639 0.0714285714285714 0.963355385569568 0.602657408673418 0.848169534863957 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/1382 12/18639 0.0833333333333333 1.12391461649783 0.603366782865871 0.848169534863957 GO:0003995 acyl-CoA dehydrogenase activity 1/1382 12/18639 0.0833333333333333 1.12391461649783 0.603366782865871 0.848169534863957 GO:0004526 ribonuclease P activity 1/1382 12/18639 0.0833333333333333 1.12391461649783 0.603366782865871 0.848169534863957 GO:0005095 GTPase inhibitor activity 1/1382 12/18639 0.0833333333333333 1.12391461649783 0.603366782865871 0.848169534863957 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/1382 12/18639 0.0833333333333333 1.12391461649783 0.603366782865871 0.848169534863957 GO:0008504 monoamine transmembrane transporter activity 1/1382 12/18639 0.0833333333333333 1.12391461649783 0.603366782865871 0.848169534863957 GO:0010853 cyclase activator activity 1/1382 12/18639 0.0833333333333333 1.12391461649783 0.603366782865871 0.848169534863957 GO:0015269 calcium-activated potassium channel activity 1/1382 12/18639 0.0833333333333333 1.12391461649783 0.603366782865871 0.848169534863957 GO:0016273 arginine N-methyltransferase activity 1/1382 12/18639 0.0833333333333333 1.12391461649783 0.603366782865871 0.848169534863957 GO:0016274 protein-arginine N-methyltransferase activity 1/1382 12/18639 0.0833333333333333 1.12391461649783 0.603366782865871 0.848169534863957 GO:0035197 siRNA binding 1/1382 12/18639 0.0833333333333333 1.12391461649783 0.603366782865871 0.848169534863957 GO:0036009 protein-glutamine N-methyltransferase activity 1/1382 12/18639 0.0833333333333333 1.12391461649783 0.603366782865871 0.848169534863957 GO:0042301 phosphate ion binding 1/1382 12/18639 0.0833333333333333 1.12391461649783 0.603366782865871 0.848169534863957 GO:0043047 single-stranded telomeric DNA binding 1/1382 12/18639 0.0833333333333333 1.12391461649783 0.603366782865871 0.848169534863957 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/1382 12/18639 0.0833333333333333 1.12391461649783 0.603366782865871 0.848169534863957 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/1382 12/18639 0.0833333333333333 1.12391461649783 0.603366782865871 0.848169534863957 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/1382 12/18639 0.0833333333333333 1.12391461649783 0.603366782865871 0.848169534863957 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/1382 12/18639 0.0833333333333333 1.12391461649783 0.603366782865871 0.848169534863957 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/1382 12/18639 0.0833333333333333 1.12391461649783 0.603366782865871 0.848169534863957 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/1382 12/18639 0.0833333333333333 1.12391461649783 0.603366782865871 0.848169534863957 GO:0140900 chloride:bicarbonate antiporter activity 1/1382 12/18639 0.0833333333333333 1.12391461649783 0.603366782865871 0.848169534863957 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/1382 12/18639 0.0833333333333333 1.12391461649783 0.603366782865871 0.848169534863957 GO:1990247 N6-methyladenosine-containing RNA reader activity 1/1382 12/18639 0.0833333333333333 1.12391461649783 0.603366782865871 0.848169534863957 GO:0019212 phosphatase inhibitor activity 4/1382 56/18639 0.0714285714285714 0.963355385569568 0.604349665146942 0.848538624008459 GO:0005044 scavenger receptor activity 2/1382 27/18639 0.0740740740740741 0.999035214664737 0.605141480396993 0.848638885604355 GO:0005525 GTP binding 27/1382 378/18639 0.0714285714285714 0.963355385569568 0.609472902173159 0.85369688318666 GO:0042056 chemoattractant activity 3/1382 42/18639 0.0714285714285714 0.963355385569568 0.61140726245604 0.855389257925434 GO:0005216 monoatomic ion channel activity 32/1382 448/18639 0.0714285714285714 0.963355385569568 0.614431718417775 0.858063073011351 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 9/1382 128/18639 0.0703125 0.948302957670043 0.614775240765348 0.858063073011351 GO:0022843 voltage-gated monoatomic cation channel activity 10/1382 143/18639 0.0699300699300699 0.943145132725451 0.622796927722212 0.86363047533787 GO:0008200 ion channel inhibitor activity 3/1382 43/18639 0.0697674418604651 0.940951771951671 0.627529869288105 0.86363047533787 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/1382 13/18639 0.0769230769230769 1.037459645998 0.632794339964672 0.86363047533787 GO:0004465 lipoprotein lipase activity 1/1382 13/18639 0.0769230769230769 1.037459645998 0.632794339964672 0.86363047533787 GO:0004535 poly(A)-specific ribonuclease activity 1/1382 13/18639 0.0769230769230769 1.037459645998 0.632794339964672 0.86363047533787 GO:0005035 death receptor activity 1/1382 13/18639 0.0769230769230769 1.037459645998 0.632794339964672 0.86363047533787 GO:0005172 vascular endothelial growth factor receptor binding 1/1382 13/18639 0.0769230769230769 1.037459645998 0.632794339964672 0.86363047533787 GO:0005338 nucleotide-sugar transmembrane transporter activity 1/1382 13/18639 0.0769230769230769 1.037459645998 0.632794339964672 0.86363047533787 GO:0008417 fucosyltransferase activity 1/1382 13/18639 0.0769230769230769 1.037459645998 0.632794339964672 0.86363047533787 GO:0009982 pseudouridine synthase activity 1/1382 13/18639 0.0769230769230769 1.037459645998 0.632794339964672 0.86363047533787 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/1382 13/18639 0.0769230769230769 1.037459645998 0.632794339964672 0.86363047533787 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/1382 13/18639 0.0769230769230769 1.037459645998 0.632794339964672 0.86363047533787 GO:0019104 DNA N-glycosylase activity 1/1382 13/18639 0.0769230769230769 1.037459645998 0.632794339964672 0.86363047533787 GO:0030955 potassium ion binding 1/1382 13/18639 0.0769230769230769 1.037459645998 0.632794339964672 0.86363047533787 GO:0031432 titin binding 1/1382 13/18639 0.0769230769230769 1.037459645998 0.632794339964672 0.86363047533787 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/1382 13/18639 0.0769230769230769 1.037459645998 0.632794339964672 0.86363047533787 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/1382 13/18639 0.0769230769230769 1.037459645998 0.632794339964672 0.86363047533787 GO:0097157 pre-mRNA intronic binding 1/1382 13/18639 0.0769230769230769 1.037459645998 0.632794339964672 0.86363047533787 GO:0016298 lipase activity 9/1382 130/18639 0.0692307692307692 0.933713681398197 0.633426766291952 0.86363047533787 GO:0016798 hydrolase activity, acting on glycosyl bonds 9/1382 130/18639 0.0692307692307692 0.933713681398197 0.633426766291952 0.86363047533787 GO:0008234 cysteine-type peptidase activity 13/1382 187/18639 0.0695187165775401 0.937597220180007 0.63634896120478 0.866611648900845 GO:0001046 core promoter sequence-specific DNA binding 3/1382 44/18639 0.0681818181818182 0.919566504407315 0.643185039871064 0.872893982682158 GO:0019205 nucleobase-containing compound kinase activity 3/1382 44/18639 0.0681818181818182 0.919566504407315 0.643185039871064 0.872893982682158 GO:0030020 extracellular matrix structural constituent conferring tensile strength 3/1382 44/18639 0.0681818181818182 0.919566504407315 0.643185039871064 0.872893982682158 GO:0004181 metallocarboxypeptidase activity 2/1382 29/18639 0.0689655172413793 0.930136234343031 0.644428251263928 0.873574775591377 GO:0019208 phosphatase regulator activity 8/1382 117/18639 0.0683760683760684 0.922186351998219 0.645481953738815 0.873997404027959 GO:0003689 DNA clamp loader activity 11/1382 160/18639 0.06875 0.927229558610709 0.646878227892915 0.874882379400522 GO:0140098 catalytic activity, acting on RNA 27/1382 387/18639 0.0697674418604651 0.940951771951671 0.658397039301687 0.88055170477107 GO:0005347 ATP transmembrane transporter activity 1/1382 14/18639 0.0714285714285714 0.963355385569568 0.660040029976957 0.88055170477107 GO:0008174 mRNA methyltransferase activity 1/1382 14/18639 0.0714285714285714 0.963355385569568 0.660040029976957 0.88055170477107 GO:0015926 glucosidase activity 1/1382 14/18639 0.0714285714285714 0.963355385569568 0.660040029976957 0.88055170477107 GO:0032454 histone H3K9 demethylase activity 1/1382 14/18639 0.0714285714285714 0.963355385569568 0.660040029976957 0.88055170477107 GO:0042813 Wnt receptor activity 1/1382 14/18639 0.0714285714285714 0.963355385569568 0.660040029976957 0.88055170477107 GO:0044548 S100 protein binding 1/1382 14/18639 0.0714285714285714 0.963355385569568 0.660040029976957 0.88055170477107 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 1/1382 14/18639 0.0714285714285714 0.963355385569568 0.660040029976957 0.88055170477107 GO:0061665 SUMO ligase activity 1/1382 14/18639 0.0714285714285714 0.963355385569568 0.660040029976957 0.88055170477107 GO:0098847 sequence-specific single stranded DNA binding 1/1382 14/18639 0.0714285714285714 0.963355385569568 0.660040029976957 0.88055170477107 GO:1901474 azole transmembrane transporter activity 1/1382 14/18639 0.0714285714285714 0.963355385569568 0.660040029976957 0.88055170477107 GO:1901612 cardiolipin binding 1/1382 14/18639 0.0714285714285714 0.963355385569568 0.660040029976957 0.88055170477107 GO:0015215 nucleotide transmembrane transporter activity 2/1382 30/18639 0.0666666666666667 0.899131693198263 0.66288150358528 0.881582283162969 GO:0033612 receptor serine/threonine kinase binding 2/1382 30/18639 0.0666666666666667 0.899131693198263 0.66288150358528 0.881582283162969 GO:0008083 growth factor activity 11/1382 162/18639 0.0679012345679012 0.915782280109342 0.663057642514763 0.881582283162969 GO:0022836 gated channel activity 22/1382 318/18639 0.0691823899371069 0.933061191054802 0.664409765348233 0.882384107756729 GO:0051087 protein-folding chaperone binding 9/1382 134/18639 0.0671641791044776 0.905841631207206 0.669210879469661 0.887759477494662 GO:0004180 carboxypeptidase activity 3/1382 46/18639 0.0652173913043478 0.879585352041779 0.673081555647891 0.890713434327729 GO:0140713 histone chaperone activity 11/1382 164/18639 0.0670731707317073 0.904614203522643 0.678809870633356 0.890713434327729 GO:0005452 solute:inorganic anion antiporter activity 2/1382 31/18639 0.0645161290322581 0.870127445030577 0.680555436901449 0.890713434327729 GO:0070273 phosphatidylinositol-4-phosphate binding 2/1382 31/18639 0.0645161290322581 0.870127445030577 0.680555436901449 0.890713434327729 GO:0003697 single-stranded DNA binding 8/1382 121/18639 0.0661157024793388 0.891700852758608 0.682508714001909 0.890713434327729 GO:0003724 RNA helicase activity 5/1382 77/18639 0.0649350649350649 0.875777623245062 0.684333959746073 0.890713434327729 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/1382 15/18639 0.0666666666666667 0.899131693198263 0.685265516074774 0.890713434327729 GO:0004953 icosanoid receptor activity 1/1382 15/18639 0.0666666666666667 0.899131693198263 0.685265516074774 0.890713434327729 GO:0005041 low-density lipoprotein particle receptor activity 1/1382 15/18639 0.0666666666666667 0.899131693198263 0.685265516074774 0.890713434327729 GO:0015116 sulfate transmembrane transporter activity 1/1382 15/18639 0.0666666666666667 0.899131693198263 0.685265516074774 0.890713434327729 GO:0015250 water channel activity 1/1382 15/18639 0.0666666666666667 0.899131693198263 0.685265516074774 0.890713434327729 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/1382 15/18639 0.0666666666666667 0.899131693198263 0.685265516074774 0.890713434327729 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 1/1382 15/18639 0.0666666666666667 0.899131693198263 0.685265516074774 0.890713434327729 GO:0016846 carbon-sulfur lyase activity 1/1382 15/18639 0.0666666666666667 0.899131693198263 0.685265516074774 0.890713434327729 GO:0048531 beta-1,3-galactosyltransferase activity 1/1382 15/18639 0.0666666666666667 0.899131693198263 0.685265516074774 0.890713434327729 GO:0141050 histone H3K deacetylase activity 1/1382 15/18639 0.0666666666666667 0.899131693198263 0.685265516074774 0.890713434327729 GO:0141051 histone H4K deacetylase activity 1/1382 15/18639 0.0666666666666667 0.899131693198263 0.685265516074774 0.890713434327729 GO:0099094 ligand-gated monoatomic cation channel activity 9/1382 136/18639 0.0661764705882353 0.892520430748276 0.686303178374821 0.890713434327729 GO:0005504 fatty acid binding 3/1382 47/18639 0.0638297872340425 0.860870770083444 0.687321654519325 0.890713434327729 GO:0140938 histone H3 methyltransferase activity 3/1382 47/18639 0.0638297872340425 0.860870770083444 0.687321654519325 0.890713434327729 GO:0008236 serine-type peptidase activity 13/1382 194/18639 0.0670103092783505 0.903766392647739 0.688010290738636 0.890713434327729 GO:0004842 ubiquitin-protein transferase activity 31/1382 449/18639 0.0690423162583519 0.931172020795529 0.688072347400878 0.890713434327729 GO:0015106 bicarbonate transmembrane transporter activity 2/1382 32/18639 0.0625 0.842935962373372 0.697464082319728 0.899977888435178 GO:0030515 snoRNA binding 2/1382 32/18639 0.0625 0.842935962373372 0.697464082319728 0.899977888435178 GO:0005496 steroid binding 7/1382 108/18639 0.0648148148148148 0.874155812831645 0.69772948986617 0.899977888435178 GO:0140693 molecular condensate scaffold activity 3/1382 48/18639 0.0625 0.842935962373372 0.70109149175885 0.899977888435178 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 11/1382 167/18639 0.0658682634730539 0.888363648968344 0.701608215523897 0.899977888435178 GO:0003712 transcription coregulator activity 34/1382 495/18639 0.0686868686868687 0.926378108143665 0.70553280442357 0.899977888435178 GO:0008186 ATP-dependent activity, acting on RNA 5/1382 79/18639 0.0632911392405063 0.853606037846453 0.706004875395595 0.899977888435178 GO:0016835 carbon-oxygen lyase activity 5/1382 79/18639 0.0632911392405063 0.853606037846453 0.706004875395595 0.899977888435178 GO:0033293 monocarboxylic acid binding 5/1382 79/18639 0.0632911392405063 0.853606037846453 0.706004875395595 0.899977888435178 GO:0004620 phospholipase activity 7/1382 109/18639 0.0642201834862385 0.866136034732272 0.706864514939534 0.899977888435178 GO:0005159 insulin-like growth factor receptor binding 1/1382 16/18639 0.0625 0.842935962373372 0.708620491202816 0.899977888435178 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/1382 16/18639 0.0625 0.842935962373372 0.708620491202816 0.899977888435178 GO:0015378 sodium:chloride symporter activity 1/1382 16/18639 0.0625 0.842935962373372 0.708620491202816 0.899977888435178 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/1382 16/18639 0.0625 0.842935962373372 0.708620491202816 0.899977888435178 GO:0070411 I-SMAD binding 1/1382 16/18639 0.0625 0.842935962373372 0.708620491202816 0.899977888435178 GO:0097027 ubiquitin-protein transferase activator activity 1/1382 16/18639 0.0625 0.842935962373372 0.708620491202816 0.899977888435178 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/1382 16/18639 0.0625 0.842935962373372 0.708620491202816 0.899977888435178 GO:0005201 extracellular matrix structural constituent 11/1382 168/18639 0.0654761904761905 0.883075770105437 0.708980883249444 0.899977888435178 GO:0017171 serine hydrolase activity 13/1382 198/18639 0.0656565656565657 0.885508485725563 0.715502593985396 0.906271147677801 GO:0000049 tRNA binding 5/1382 80/18639 0.0625 0.842935962373372 0.71644232939472 0.906271147677801 GO:0048306 calcium-dependent protein binding 5/1382 80/18639 0.0625 0.842935962373372 0.71644232939472 0.906271147677801 GO:0015035 protein-disulfide reductase activity 2/1382 34/18639 0.0588235294117647 0.793351493998468 0.729052248452099 0.906271147677801 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 2/1382 34/18639 0.0588235294117647 0.793351493998468 0.729052248452099 0.906271147677801 GO:0030332 cyclin binding 2/1382 34/18639 0.0588235294117647 0.793351493998468 0.729052248452099 0.906271147677801 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/1382 17/18639 0.0588235294117647 0.793351493998468 0.730243563809685 0.906271147677801 GO:0005092 GDP-dissociation inhibitor activity 1/1382 17/18639 0.0588235294117647 0.793351493998468 0.730243563809685 0.906271147677801 GO:0008569 minus-end-directed microtubule motor activity 1/1382 17/18639 0.0588235294117647 0.793351493998468 0.730243563809685 0.906271147677801 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/1382 17/18639 0.0588235294117647 0.793351493998468 0.730243563809685 0.906271147677801 GO:0009881 photoreceptor activity 1/1382 17/18639 0.0588235294117647 0.793351493998468 0.730243563809685 0.906271147677801 GO:0016018 cyclosporin A binding 1/1382 17/18639 0.0588235294117647 0.793351493998468 0.730243563809685 0.906271147677801 GO:0016805 dipeptidase activity 1/1382 17/18639 0.0588235294117647 0.793351493998468 0.730243563809685 0.906271147677801 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/1382 17/18639 0.0588235294117647 0.793351493998468 0.730243563809685 0.906271147677801 GO:0036041 long-chain fatty acid binding 1/1382 17/18639 0.0588235294117647 0.793351493998468 0.730243563809685 0.906271147677801 GO:0038191 neuropilin binding 1/1382 17/18639 0.0588235294117647 0.793351493998468 0.730243563809685 0.906271147677801 GO:0046965 nuclear retinoid X receptor binding 1/1382 17/18639 0.0588235294117647 0.793351493998468 0.730243563809685 0.906271147677801 GO:0048038 quinone binding 1/1382 17/18639 0.0588235294117647 0.793351493998468 0.730243563809685 0.906271147677801 GO:0070403 NAD+ binding 1/1382 17/18639 0.0588235294117647 0.793351493998468 0.730243563809685 0.906271147677801 GO:0070492 oligosaccharide binding 1/1382 17/18639 0.0588235294117647 0.793351493998468 0.730243563809685 0.906271147677801 GO:1990226 histone methyltransferase binding 1/1382 17/18639 0.0588235294117647 0.793351493998468 0.730243563809685 0.906271147677801 GO:0008235 metalloexopeptidase activity 4/1382 66/18639 0.0606060606060606 0.817392448362058 0.73086382877242 0.906271147677801 GO:0015276 ligand-gated monoatomic ion channel activity 12/1382 186/18639 0.0645161290322581 0.870127445030577 0.732677119998546 0.907420260437467 GO:0019783 ubiquitin-like protein peptidase activity 8/1382 127/18639 0.062992125984252 0.849573253415682 0.733331144258462 0.907420260437467 GO:0020037 heme binding 9/1382 142/18639 0.0633802816901408 0.854808299871588 0.734214468547268 0.907559962170704 GO:0003743 translation initiation factor activity 3/1382 51/18639 0.0588235294117647 0.793351493998468 0.739617057410279 0.908334949622683 GO:0005272 sodium channel activity 3/1382 51/18639 0.0588235294117647 0.793351493998468 0.739617057410279 0.908334949622683 GO:0030544 Hsp70 protein binding 3/1382 51/18639 0.0588235294117647 0.793351493998468 0.739617057410279 0.908334949622683 GO:0008173 RNA methyltransferase activity 4/1382 67/18639 0.0597014925373134 0.805192561073072 0.741665708842037 0.908334949622683 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 4/1382 67/18639 0.0597014925373134 0.805192561073072 0.741665708842037 0.908334949622683 GO:0061631 ubiquitin conjugating enzyme activity 2/1382 35/18639 0.0571428571428571 0.770684308455654 0.743769283314748 0.908334949622683 GO:0140030 modification-dependent protein binding 11/1382 173/18639 0.0635838150289017 0.857553349004124 0.74409948368947 0.908334949622683 GO:0022834 ligand-gated channel activity 12/1382 188/18639 0.0638297872340425 0.860870770083444 0.745779596150204 0.908334949622683 GO:0140597 protein carrier chaperone 12/1382 188/18639 0.0638297872340425 0.860870770083444 0.745779596150204 0.908334949622683 GO:0000400 four-way junction DNA binding 1/1382 18/18639 0.0555555555555556 0.749276410998553 0.750263078083931 0.908334949622683 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/1382 18/18639 0.0555555555555556 0.749276410998553 0.750263078083931 0.908334949622683 GO:0005372 water transmembrane transporter activity 1/1382 18/18639 0.0555555555555556 0.749276410998553 0.750263078083931 0.908334949622683 GO:0015373 monoatomic anion:sodium symporter activity 1/1382 18/18639 0.0555555555555556 0.749276410998553 0.750263078083931 0.908334949622683 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/1382 18/18639 0.0555555555555556 0.749276410998553 0.750263078083931 0.908334949622683 GO:0022851 GABA-gated chloride ion channel activity 1/1382 18/18639 0.0555555555555556 0.749276410998553 0.750263078083931 0.908334949622683 GO:0031690 adrenergic receptor binding 1/1382 18/18639 0.0555555555555556 0.749276410998553 0.750263078083931 0.908334949622683 GO:0050811 GABA receptor binding 1/1382 18/18639 0.0555555555555556 0.749276410998553 0.750263078083931 0.908334949622683 GO:0070628 proteasome binding 1/1382 18/18639 0.0555555555555556 0.749276410998553 0.750263078083931 0.908334949622683 GO:0098641 cadherin binding involved in cell-cell adhesion 1/1382 18/18639 0.0555555555555556 0.749276410998553 0.750263078083931 0.908334949622683 GO:1990381 ubiquitin-specific protease binding 1/1382 18/18639 0.0555555555555556 0.749276410998553 0.750263078083931 0.908334949622683 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 3/1382 52/18639 0.0576923076923077 0.778094734498497 0.751549144451912 0.908733222822755 GO:0003777 microtubule motor activity 4/1382 68/18639 0.0588235294117647 0.793351493998468 0.752134883066372 0.908733222822755 GO:0101005 deubiquitinase activity 7/1382 115/18639 0.0608695652173913 0.820946328572327 0.757763249883129 0.910900988972879 GO:0045505 dynein intermediate chain binding 2/1382 36/18639 0.0555555555555556 0.749276410998553 0.757795389807659 0.910900988972879 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 2/1382 36/18639 0.0555555555555556 0.749276410998553 0.757795389807659 0.910900988972879 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 2/1382 36/18639 0.0555555555555556 0.749276410998553 0.757795389807659 0.910900988972879 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 2/1382 36/18639 0.0555555555555556 0.749276410998553 0.757795389807659 0.910900988972879 GO:0005544 calcium-dependent phospholipid binding 3/1382 53/18639 0.0566037735849057 0.76341370177211 0.763037843433184 0.915334602407628 GO:0140296 general transcription initiation factor binding 3/1382 53/18639 0.0566037735849057 0.76341370177211 0.763037843433184 0.915334602407628 GO:0031072 heat shock protein binding 8/1382 131/18639 0.0610687022900763 0.823632085372455 0.763965863518967 0.915515551602587 GO:0004890 GABA-A receptor activity 1/1382 19/18639 0.0526315789473684 0.709840810419682 0.768797873534659 0.915716779599422 GO:0008574 plus-end-directed microtubule motor activity 1/1382 19/18639 0.0526315789473684 0.709840810419682 0.768797873534659 0.915716779599422 GO:0015245 fatty acid transmembrane transporter activity 1/1382 19/18639 0.0526315789473684 0.709840810419682 0.768797873534659 0.915716779599422 GO:0030506 ankyrin binding 1/1382 19/18639 0.0526315789473684 0.709840810419682 0.768797873534659 0.915716779599422 GO:0034987 immunoglobulin receptor binding 1/1382 19/18639 0.0526315789473684 0.709840810419682 0.768797873534659 0.915716779599422 GO:0140036 ubiquitin-modified protein reader activity 1/1382 19/18639 0.0526315789473684 0.709840810419682 0.768797873534659 0.915716779599422 GO:0061630 ubiquitin protein ligase activity 23/1382 353/18639 0.0651558073654391 0.878754770972807 0.77074386871326 0.916667101667197 GO:0070001 aspartic-type peptidase activity 2/1382 37/18639 0.0540540540540541 0.729025697187781 0.771152035443287 0.916667101667197 GO:0003925 G protein activity 3/1382 54/18639 0.0555555555555556 0.749276410998553 0.774091240464737 0.919233348051875 GO:0008238 exopeptidase activity 6/1382 102/18639 0.0588235294117647 0.793351493998468 0.776647521206967 0.921340161109574 GO:0042887 amide transmembrane transporter activity 2/1382 38/18639 0.0526315789473684 0.709840810419682 0.783861304446712 0.923089242606271 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 1/1382 20/18639 0.05 0.674348769898698 0.785957988399058 0.923089242606271 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/1382 20/18639 0.05 0.674348769898698 0.785957988399058 0.923089242606271 GO:0010851 cyclase regulator activity 1/1382 20/18639 0.05 0.674348769898698 0.785957988399058 0.923089242606271 GO:0015095 magnesium ion transmembrane transporter activity 1/1382 20/18639 0.05 0.674348769898698 0.785957988399058 0.923089242606271 GO:0016004 phospholipase activator activity 1/1382 20/18639 0.05 0.674348769898698 0.785957988399058 0.923089242606271 GO:0043024 ribosomal small subunit binding 1/1382 20/18639 0.05 0.674348769898698 0.785957988399058 0.923089242606271 GO:0061608 nuclear import signal receptor activity 1/1382 20/18639 0.05 0.674348769898698 0.785957988399058 0.923089242606271 GO:0140664 ATP-dependent DNA damage sensor activity 1/1382 20/18639 0.05 0.674348769898698 0.785957988399058 0.923089242606271 GO:0140939 histone H4 methyltransferase activity 1/1382 20/18639 0.05 0.674348769898698 0.785957988399058 0.923089242606271 GO:0015103 inorganic anion transmembrane transporter activity 10/1382 165/18639 0.0606060606060606 0.817392448362058 0.788854083090849 0.925567838526913 GO:0061659 ubiquitin-like protein ligase activity 24/1382 372/18639 0.0645161290322581 0.870127445030577 0.790197599609934 0.9262216640204 GO:0000217 DNA secondary structure binding 2/1382 39/18639 0.0512820512820513 0.691639763998664 0.795945688484919 0.929083305602434 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 2/1382 39/18639 0.0512820512820513 0.691639763998664 0.795945688484919 0.929083305602434 GO:0016758 hexosyltransferase activity 12/1382 197/18639 0.0609137055837563 0.82154164860755 0.799352516238675 0.929083305602434 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 4/1382 73/18639 0.0547945205479452 0.739012350573915 0.799620774194428 0.929083305602434 GO:0005123 death receptor binding 1/1382 21/18639 0.0476190476190476 0.642236923713045 0.801845311028227 0.929083305602434 GO:0035613 RNA stem-loop binding 1/1382 21/18639 0.0476190476190476 0.642236923713045 0.801845311028227 0.929083305602434 GO:0070182 DNA polymerase binding 1/1382 21/18639 0.0476190476190476 0.642236923713045 0.801845311028227 0.929083305602434 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 2/1382 40/18639 0.05 0.674348769898698 0.80742790499932 0.929083305602434 GO:0061791 GTPase motor activity 2/1382 40/18639 0.05 0.674348769898698 0.80742790499932 0.929083305602434 GO:1990606 membrane scission GTPase motor activity 2/1382 40/18639 0.05 0.674348769898698 0.80742790499932 0.929083305602434 GO:0031491 nucleosome binding 4/1382 74/18639 0.0540540540540541 0.729025697187781 0.808178614065011 0.929083305602434 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 5/1382 91/18639 0.0549450549450549 0.741042604284283 0.813991394794305 0.929083305602434 GO:0019003 GDP binding 4/1382 75/18639 0.0533333333333333 0.719305354558611 0.816436001277296 0.929083305602434 GO:0004407 histone deacetylase activity 1/1382 22/18639 0.0454545454545455 0.613044336271543 0.816554183096064 0.929083305602434 GO:0005243 gap junction channel activity 1/1382 22/18639 0.0454545454545455 0.613044336271543 0.816554183096064 0.929083305602434 GO:0008649 rRNA methyltransferase activity 1/1382 22/18639 0.0454545454545455 0.613044336271543 0.816554183096064 0.929083305602434 GO:0008970 phospholipase A1 activity 1/1382 22/18639 0.0454545454545455 0.613044336271543 0.816554183096064 0.929083305602434 GO:0033558 protein lysine deacetylase activity 1/1382 22/18639 0.0454545454545455 0.613044336271543 0.816554183096064 0.929083305602434 GO:0033691 sialic acid binding 1/1382 22/18639 0.0454545454545455 0.613044336271543 0.816554183096064 0.929083305602434 GO:0034062 5'-3' RNA polymerase activity 1/1382 22/18639 0.0454545454545455 0.613044336271543 0.816554183096064 0.929083305602434 GO:0050321 tau-protein kinase activity 1/1382 22/18639 0.0454545454545455 0.613044336271543 0.816554183096064 0.929083305602434 GO:0070034 telomerase RNA binding 1/1382 22/18639 0.0454545454545455 0.613044336271543 0.816554183096064 0.929083305602434 GO:0097747 RNA polymerase activity 1/1382 22/18639 0.0454545454545455 0.613044336271543 0.816554183096064 0.929083305602434 GO:0140035 ubiquitin-like protein reader activity 1/1382 22/18639 0.0454545454545455 0.613044336271543 0.816554183096064 0.929083305602434 GO:0140767 enzyme-substrate adaptor activity 8/1382 139/18639 0.0575539568345324 0.776228799883393 0.817473911441431 0.929083305602434 GO:0004812 aminoacyl-tRNA ligase activity 2/1382 41/18639 0.0487804878048781 0.657901238925559 0.81833074020339 0.929083305602434 GO:0016875 ligase activity, forming carbon-oxygen bonds 2/1382 41/18639 0.0487804878048781 0.657901238925559 0.81833074020339 0.929083305602434 GO:0004386 helicase activity 9/1382 155/18639 0.0580645161290323 0.78311470052752 0.82024618388565 0.929083305602434 GO:0005267 potassium channel activity 7/1382 124/18639 0.0564516129032258 0.761361514401755 0.821636867097158 0.929083305602434 GO:0036002 pre-mRNA binding 3/1382 59/18639 0.0508474576271186 0.685778410066472 0.823151643560393 0.929083305602434 GO:0051536 iron-sulfur cluster binding 4/1382 76/18639 0.0526315789473684 0.709840810419682 0.824398963677099 0.929083305602434 GO:0098631 cell adhesion mediator activity 4/1382 76/18639 0.0526315789473684 0.709840810419682 0.824398963677099 0.929083305602434 GO:0031406 carboxylic acid binding 11/1382 187/18639 0.0588235294117647 0.793351493998468 0.826725803449804 0.929083305602434 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 31/1382 484/18639 0.0640495867768595 0.863835201109902 0.827673043896371 0.929083305602434 GO:0051213 dioxygenase activity 5/1382 93/18639 0.0537634408602151 0.725106204192148 0.828473107739042 0.929083305602434 GO:0004520 DNA endonuclease activity 2/1382 42/18639 0.0476190476190476 0.642236923713045 0.828676914090757 0.929083305602434 GO:0016859 cis-trans isomerase activity 2/1382 42/18639 0.0476190476190476 0.642236923713045 0.828676914090757 0.929083305602434 GO:0019894 kinesin binding 2/1382 42/18639 0.0476190476190476 0.642236923713045 0.828676914090757 0.929083305602434 GO:0031492 nucleosomal DNA binding 2/1382 42/18639 0.0476190476190476 0.642236923713045 0.828676914090757 0.929083305602434 GO:0008201 heparin binding 10/1382 172/18639 0.0581395348837209 0.784126476626392 0.828686497222911 0.929083305602434 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/1382 23/18639 0.0434782608695652 0.58639023469452 0.830171958192011 0.929083305602434 GO:0004602 glutathione peroxidase activity 1/1382 23/18639 0.0434782608695652 0.58639023469452 0.830171958192011 0.929083305602434 GO:0005212 structural constituent of eye lens 1/1382 23/18639 0.0434782608695652 0.58639023469452 0.830171958192011 0.929083305602434 GO:0016917 GABA receptor activity 1/1382 23/18639 0.0434782608695652 0.58639023469452 0.830171958192011 0.929083305602434 GO:0140102 catalytic activity, acting on a rRNA 1/1382 23/18639 0.0434782608695652 0.58639023469452 0.830171958192011 0.929083305602434 GO:0140103 catalytic activity, acting on a glycoprotein 1/1382 23/18639 0.0434782608695652 0.58639023469452 0.830171958192011 0.929083305602434 GO:0001098 basal transcription machinery binding 3/1382 60/18639 0.05 0.674348769898698 0.831792814211997 0.929083305602434 GO:0001099 basal RNA polymerase II transcription machinery binding 3/1382 60/18639 0.05 0.674348769898698 0.831792814211997 0.929083305602434 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 3/1382 60/18639 0.05 0.674348769898698 0.831792814211997 0.929083305602434 GO:0051540 metal cluster binding 4/1382 77/18639 0.051948051948052 0.700622098596049 0.832073758413046 0.929083305602434 GO:0043177 organic acid binding 11/1382 189/18639 0.0582010582010582 0.784956240093722 0.836674734722884 0.930453864568373 GO:0008375 acetylglucosaminyltransferase activity 2/1382 43/18639 0.0465116279069767 0.627301181301114 0.83848896505674 0.930453864568373 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/1382 43/18639 0.0465116279069767 0.627301181301114 0.83848896505674 0.930453864568373 GO:0008276 protein methyltransferase activity 5/1382 95/18639 0.0526315789473684 0.709840810419682 0.842025037114881 0.930453864568373 GO:0004622 lysophospholipase activity 1/1382 24/18639 0.0416666666666667 0.561957308248915 0.842779519095462 0.930453864568373 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/1382 24/18639 0.0416666666666667 0.561957308248915 0.842779519095462 0.930453864568373 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/1382 24/18639 0.0416666666666667 0.561957308248915 0.842779519095462 0.930453864568373 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/1382 24/18639 0.0416666666666667 0.561957308248915 0.842779519095462 0.930453864568373 GO:0060229 lipase activator activity 1/1382 24/18639 0.0416666666666667 0.561957308248915 0.842779519095462 0.930453864568373 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/1382 24/18639 0.0416666666666667 0.561957308248915 0.842779519095462 0.930453864568373 GO:0070840 dynein complex binding 1/1382 24/18639 0.0416666666666667 0.561957308248915 0.842779519095462 0.930453864568373 GO:0140612 DNA damage sensor activity 1/1382 24/18639 0.0416666666666667 0.561957308248915 0.842779519095462 0.930453864568373 GO:0031490 chromatin DNA binding 7/1382 128/18639 0.0546875 0.7375689670767 0.84543988686536 0.932517028770968 GO:0016790 thiolester hydrolase activity 2/1382 44/18639 0.0454545454545455 0.613044336271543 0.847789151970344 0.933463515187022 GO:0001216 DNA-binding transcription activator activity 31/1382 491/18639 0.0631364562118126 0.851519831643976 0.849266685118202 0.933463515187022 GO:0043021 ribonucleoprotein complex binding 10/1382 177/18639 0.0564971751412429 0.761976011184969 0.853427180004883 0.933463515187022 GO:0015662 P-type ion transporter activity 1/1382 25/18639 0.04 0.539479015918958 0.854451756786038 0.933463515187022 GO:0017025 TBP-class protein binding 1/1382 25/18639 0.04 0.539479015918958 0.854451756786038 0.933463515187022 GO:0042974 nuclear retinoic acid receptor binding 1/1382 25/18639 0.04 0.539479015918958 0.854451756786038 0.933463515187022 GO:0047617 fatty acyl-CoA hydrolase activity 1/1382 25/18639 0.04 0.539479015918958 0.854451756786038 0.933463515187022 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/1382 25/18639 0.04 0.539479015918958 0.854451756786038 0.933463515187022 GO:0140358 P-type transmembrane transporter activity 1/1382 25/18639 0.04 0.539479015918958 0.854451756786038 0.933463515187022 GO:0022824 transmitter-gated monoatomic ion channel activity 3/1382 63/18639 0.0476190476190476 0.642236923713045 0.855567049202748 0.933463515187022 GO:0022835 transmitter-gated channel activity 3/1382 63/18639 0.0476190476190476 0.642236923713045 0.855567049202748 0.933463515187022 GO:0008009 chemokine activity 2/1382 45/18639 0.0444444444444444 0.599421128798842 0.856599371746325 0.933463515187022 GO:0051539 4 iron, 4 sulfur cluster binding 2/1382 45/18639 0.0444444444444444 0.599421128798842 0.856599371746325 0.933463515187022 GO:0005249 voltage-gated potassium channel activity 5/1382 98/18639 0.0510204081632653 0.688110989692548 0.860687791981268 0.937051958367777 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 2/1382 46/18639 0.0434782608695652 0.58639023469452 0.864941090659891 0.939422986648461 GO:0016289 acyl-CoA hydrolase activity 1/1382 26/18639 0.0384615384615385 0.518729822998998 0.865258014018319 0.939422986648461 GO:0030507 spectrin binding 1/1382 26/18639 0.0384615384615385 0.518729822998998 0.865258014018319 0.939422986648461 GO:0140359 ABC-type transporter activity 2/1382 47/18639 0.0425531914893617 0.573913846722296 0.872835287821694 0.946777135408798 GO:1901681 sulfur compound binding 16/1382 275/18639 0.0581818181818182 0.784696750427575 0.874072836853543 0.946794509075334 GO:0019842 vitamin binding 8/1382 150/18639 0.0533333333333333 0.719305354558611 0.875162694788196 0.946794509075334 GO:0008395 steroid hydroxylase activity 1/1382 27/18639 0.037037037037037 0.499517607332368 0.875262496080678 0.946794509075334 GO:0008188 neuropeptide receptor activity 2/1382 48/18639 0.0416666666666667 0.561957308248915 0.880302409389643 0.949835951751644 GO:0042054 histone methyltransferase activity 3/1382 67/18639 0.0447761194029851 0.603894420804804 0.882661723123652 0.949835951751644 GO:0046982 protein heterodimerization activity 22/1382 369/18639 0.0596205962059621 0.804101514242349 0.882760192258525 0.949835951751644 GO:0005242 inward rectifier potassium channel activity 1/1382 28/18639 0.0357142857142857 0.481677692784784 0.884524651164307 0.949835951751644 GO:0008527 taste receptor activity 1/1382 28/18639 0.0357142857142857 0.481677692784784 0.884524651164307 0.949835951751644 GO:0016866 intramolecular transferase activity 1/1382 28/18639 0.0357142857142857 0.481677692784784 0.884524651164307 0.949835951751644 GO:0051537 2 iron, 2 sulfur cluster binding 1/1382 28/18639 0.0357142857142857 0.481677692784784 0.884524651164307 0.949835951751644 GO:0141052 histone H3 demethylase activity 1/1382 28/18639 0.0357142857142857 0.481677692784784 0.884524651164307 0.949835951751644 GO:0016779 nucleotidyltransferase activity 7/1382 136/18639 0.0514705882352941 0.694182557248659 0.885361119632552 0.949868305033831 GO:0005253 monoatomic anion channel activity 5/1382 103/18639 0.0485436893203883 0.654707543590968 0.887670072807054 0.951478931543867 GO:0016887 ATP hydrolysis activity 25/1382 417/18639 0.0599520383693046 0.808571666545201 0.890258337773027 0.95338574717875 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/1382 29/18639 0.0344827586206897 0.465068117171515 0.893099522589321 0.954692593112722 GO:0097472 cyclin-dependent protein kinase activity 1/1382 29/18639 0.0344827586206897 0.465068117171515 0.893099522589321 0.954692593112722 GO:0016279 protein-lysine N-methyltransferase activity 3/1382 69/18639 0.0434782608695652 0.58639023469452 0.89443201487534 0.955250148253083 GO:0016278 lysine N-methyltransferase activity 3/1382 70/18639 0.0428571428571429 0.578013231341741 0.899910081836981 0.958828231538583 GO:0032452 histone demethylase activity 1/1382 30/18639 0.0333333333333333 0.449565846599132 0.901038074968771 0.958828231538583 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/1382 30/18639 0.0333333333333333 0.449565846599132 0.901038074968771 0.958828231538583 GO:0070566 adenylyltransferase activity 1/1382 30/18639 0.0333333333333333 0.449565846599132 0.901038074968771 0.958828231538583 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/1382 31/18639 0.032258064516129 0.435063722515289 0.908387496237681 0.960574928696578 GO:0008327 methyl-CpG binding 1/1382 31/18639 0.032258064516129 0.435063722515289 0.908387496237681 0.960574928696578 GO:0016411 acylglycerol O-acyltransferase activity 1/1382 31/18639 0.032258064516129 0.435063722515289 0.908387496237681 0.960574928696578 GO:0017147 Wnt-protein binding 1/1382 31/18639 0.032258064516129 0.435063722515289 0.908387496237681 0.960574928696578 GO:0047499 calcium-independent phospholipase A2 activity 1/1382 31/18639 0.032258064516129 0.435063722515289 0.908387496237681 0.960574928696578 GO:0072349 modified amino acid transmembrane transporter activity 1/1382 31/18639 0.032258064516129 0.435063722515289 0.908387496237681 0.960574928696578 GO:0140457 protein demethylase activity 1/1382 31/18639 0.032258064516129 0.435063722515289 0.908387496237681 0.960574928696578 GO:0004843 cysteine-type deubiquitinase activity 5/1382 108/18639 0.0462962962962963 0.624397009165461 0.910034977465469 0.961453994129437 GO:0016251 RNA polymerase II general transcription initiation factor activity 2/1382 53/18639 0.0377358490566038 0.508942467848074 0.911906276207411 0.961705992276034 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 2/1382 53/18639 0.0377358490566038 0.508942467848074 0.911906276207411 0.961705992276034 GO:0031369 translation initiation factor binding 1/1382 32/18639 0.03125 0.421467981186686 0.915191477331809 0.962585321693634 GO:0047498 calcium-dependent phospholipase A2 activity 1/1382 32/18639 0.03125 0.421467981186686 0.915191477331809 0.962585321693634 GO:0140142 nucleocytoplasmic carrier activity 1/1382 32/18639 0.03125 0.421467981186686 0.915191477331809 0.962585321693634 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 2/1382 54/18639 0.037037037037037 0.499517607332368 0.917206854505206 0.963844491174963 GO:0098632 cell-cell adhesion mediator activity 2/1382 55/18639 0.0363636363636364 0.490435469017235 0.922206431440483 0.968234559925926 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 2/1382 56/18639 0.0357142857142857 0.481677692784784 0.926920462315009 0.972317279258309 GO:0004623 phospholipase A2 activity 1/1382 35/18639 0.0285714285714286 0.385342154227827 0.932720539791287 0.977530957183396 GO:0030594 neurotransmitter receptor activity 4/1382 97/18639 0.0412371134020619 0.55616393393707 0.935485747789189 0.978541289700239 GO:0000993 RNA polymerase II complex binding 1/1382 36/18639 0.0277777777777778 0.374638205499276 0.937718401219391 0.978541289700239 GO:0004190 aspartic-type endopeptidase activity 1/1382 36/18639 0.0277777777777778 0.374638205499276 0.937718401219391 0.978541289700239 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/1382 36/18639 0.0277777777777778 0.374638205499276 0.937718401219391 0.978541289700239 GO:0008170 N-methyltransferase activity 4/1382 98/18639 0.0408163265306122 0.550488791754039 0.938668639525696 0.978541289700239 GO:0042626 ATPase-coupled transmembrane transporter activity 4/1382 98/18639 0.0408163265306122 0.550488791754039 0.938668639525696 0.978541289700239 GO:0005506 iron ion binding 7/1382 154/18639 0.0454545454545455 0.613044336271543 0.944554721631711 0.983806774608448 GO:0042162 telomeric DNA binding 1/1382 38/18639 0.0263157894736842 0.354920405209841 0.946628594450103 0.984511193581293 GO:0003713 transcription coactivator activity 13/1382 256/18639 0.05078125 0.684885469428365 0.94690253168727 0.984511193581293 GO:0003823 antigen binding 8/1382 174/18639 0.0459770114942529 0.620090822895354 0.950339628429615 0.986073686500146 GO:0005254 chloride channel activity 3/1382 83/18639 0.036144578313253 0.487481038480986 0.951094572735795 0.986073686500146 GO:0008135 translation factor activity, RNA binding 3/1382 83/18639 0.036144578313253 0.487481038480986 0.951094572735795 0.986073686500146 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 5/1382 122/18639 0.040983606557377 0.552744893359588 0.953209117414737 0.986073686500146 GO:0180051 translation factor activity 3/1382 84/18639 0.0357142857142857 0.481677692784784 0.95379115393394 0.986073686500146 GO:0004177 aminopeptidase activity 1/1382 40/18639 0.025 0.337174384949349 0.954264857903367 0.986073686500146 GO:0032451 demethylase activity 1/1382 40/18639 0.025 0.337174384949349 0.954264857903367 0.986073686500146 GO:0004497 monooxygenase activity 4/1382 106/18639 0.0377358490566038 0.508942467848074 0.959411430717046 0.989816770788816 GO:0043175 RNA polymerase core enzyme binding 1/1382 42/18639 0.0238095238095238 0.321118461856523 0.960809218083796 0.989816770788816 GO:0051879 Hsp90 protein binding 1/1382 42/18639 0.0238095238095238 0.321118461856523 0.960809218083796 0.989816770788816 GO:0016853 isomerase activity 8/1382 180/18639 0.0444444444444444 0.599421128798842 0.961248205248222 0.989816770788816 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 8/1382 181/18639 0.0441988950276243 0.596109409855202 0.962840625639511 0.99059061747017 GO:0048156 tau protein binding 1/1382 43/18639 0.0232558139534884 0.313650590650557 0.963721605060631 0.99063180694714 GO:0140223 general transcription initiation factor activity 2/1382 68/18639 0.0294117647058824 0.396675746999234 0.966011054289367 0.992119461162053 GO:0098960 postsynaptic neurotransmitter receptor activity 2/1382 69/18639 0.0289855072463768 0.39092682312968 0.96814774203307 0.992188280177089 GO:0043022 ribosome binding 4/1382 112/18639 0.0357142857142857 0.481677692784784 0.970476288677175 0.992188280177089 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/1382 46/18639 0.0217391304347826 0.29319511734726 0.971224079674664 0.992188280177089 GO:0005179 hormone activity 5/1382 132/18639 0.0378787878787879 0.510870280226286 0.971402829274611 0.992188280177089 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 5/1382 132/18639 0.0378787878787879 0.510870280226286 0.971402829274611 0.992188280177089 GO:0061749 forked DNA-dependent helicase activity 1/1382 47/18639 0.0212765957446809 0.286956923361148 0.973362966454076 0.992188280177089 GO:0099095 ligand-gated monoatomic anion channel activity 1/1382 47/18639 0.0212765957446809 0.286956923361148 0.973362966454076 0.992188280177089 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/1382 47/18639 0.0212765957446809 0.286956923361148 0.973362966454076 0.992188280177089 GO:0009378 four-way junction helicase activity 1/1382 48/18639 0.0208333333333333 0.280978654124457 0.975342978306511 0.992188280177089 GO:0036121 double-stranded DNA helicase activity 1/1382 48/18639 0.0208333333333333 0.280978654124457 0.975342978306511 0.992188280177089 GO:0043138 3'-5' DNA helicase activity 1/1382 48/18639 0.0208333333333333 0.280978654124457 0.975342978306511 0.992188280177089 GO:0044183 protein folding chaperone 2/1382 75/18639 0.0266666666666667 0.359652677279305 0.978492203614217 0.993785970911637 GO:0042393 histone binding 11/1382 247/18639 0.0445344129554656 0.600634531893577 0.978600786296689 0.993785970911637 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4/1382 122/18639 0.0327868852459016 0.44219591468767 0.982884092433121 0.997276021435156 GO:0017069 snRNA binding 1/1382 54/18639 0.0185185185185185 0.249758803666184 0.984489358011451 0.998045149515912 GO:0008374 O-acyltransferase activity 1/1382 55/18639 0.0181818181818182 0.245217734508617 0.985642745540543 0.998355248707446 GO:0017116 single-stranded DNA helicase activity 1/1382 58/18639 0.0172413793103448 0.232534058585758 0.988613637545806 0.999999999999769 GO:0070063 RNA polymerase binding 1/1382 59/18639 0.0169491525423729 0.228592803355491 0.989460521616184 0.999999999999769 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/1382 60/18639 0.0166666666666667 0.224782923299566 0.990244459136444 0.999999999999769 GO:0016407 acetyltransferase activity 2/1382 96/18639 0.0208333333333333 0.280978654124457 0.994744650281952 0.999999999999769 GO:0008080 N-acetyltransferase activity 1/1382 69/18639 0.0144927536231884 0.19546341156484 0.995135290481367 0.999999999999769 GO:0003678 DNA helicase activity 1/1382 74/18639 0.0135135135135135 0.182256424296945 0.996695503381509 0.999999999999769 GO:0035064 methylated histone binding 1/1382 74/18639 0.0135135135135135 0.182256424296945 0.996695503381509 0.999999999999769 GO:0140034 methylation-dependent protein binding 1/1382 76/18639 0.0131578947368421 0.17746020260492 0.997169184901672 0.999999999999769 GO:0051082 unfolded protein binding 2/1382 121/18639 0.0165289256198347 0.222925213189652 0.999067202954394 0.999999999999769 GO:0016410 N-acyltransferase activity 1/1382 94/18639 0.0106382978723404 0.143478461680574 0.999297205584899 0.999999999999769 GO:0003730 mRNA 3'-UTR binding 7/1382 262/18639 0.0267175572519084 0.360339037350449 0.999754237722847 0.999999999999769 GO:0005549 odorant binding 1/1382 111/18639 0.00900900900900901 0.12150428286463 0.999811721863929 0.999999999999769 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 4/1382 229/18639 0.0174672489082969 0.235580356296488 0.999975776789863 0.999999999999769 GO:0045182 translation regulator activity 3/1382 356/18639 0.00842696629213483 0.113654287061578 0.999999999578232 0.999999999999769 GO:0004984 olfactory receptor activity 2/1382 419/18639 0.00477326968973747 0.064376970873384 0.999999999999769 0.999999999999769