ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 44/247 175/18639 0.251428571428571 18.9731868131868 5.21749137549071e-44 2.79657537726302e-41 GO:0042605 peptide antigen binding 7/247 45/18639 0.155555555555556 11.7384615384615 1.94731811100986e-06 0.000444951531691709 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 8/247 68/18639 0.117647058823529 8.87782805429864 3.1618374370729e-06 0.000444951531691709 GO:0009055 electron transfer activity 10/247 116/18639 0.0862068965517241 6.5053050397878 3.32053381859485e-06 0.000444951531691709 GO:0015078 proton transmembrane transporter activity 12/247 185/18639 0.0648648648648649 4.89480249480249 6.92476015432066e-06 0.000742334288543175 GO:0042608 T cell receptor binding 4/247 11/18639 0.363636363636364 27.4405594405594 9.2322798051806e-06 0.0008247503292628 GO:0003779 actin binding 18/247 443/18639 0.0406320541760722 3.06615731897899 2.73821922622848e-05 0.00209669357894066 GO:0045296 cadherin binding 15/247 334/18639 0.0449101796407186 3.38899124827269 4.19686956344467e-05 0.00281190260750793 GO:0022853 active monoatomic ion transmembrane transporter activity 8/247 118/18639 0.0677966101694915 5.11603650586701 0.00017729416913048 0.0105588527393264 GO:0008137 NADH dehydrogenase (ubiquinone) activity 5/247 41/18639 0.121951219512195 9.20262664165103 0.000199215518075568 0.0106779517688504 GO:0031720 haptoglobin binding 3/247 10/18639 0.3 22.6384615384615 0.000257535792068717 0.0124852677882257 GO:0003954 NADH dehydrogenase activity 5/247 44/18639 0.113636363636364 8.57517482517482 0.000279520920631919 0.0124852677882257 GO:0023026 MHC class II protein complex binding 4/247 27/18639 0.148148148148148 11.1794871794872 0.000415556816911108 0.0171337272203349 GO:0046875 ephrin receptor binding 4/247 28/18639 0.142857142857143 10.7802197802198 0.000479806002955681 0.0175483897483521 GO:0051015 actin filament binding 10/247 209/18639 0.0478468899521531 3.6105999263894 0.000491092996688958 0.0175483897483521 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 4/247 29/18639 0.137931034482759 10.4084880636605 0.000550825536305783 0.0184526554662437 GO:0005344 oxygen carrier activity 3/247 14/18639 0.214285714285714 16.1703296703297 0.000751114747014636 0.0236822061411673 GO:0071889 14-3-3 protein binding 4/247 33/18639 0.121212121212121 9.14685314685315 0.000910434531821249 0.0248988210571914 GO:0031386 protein tag activity 3/247 15/18639 0.2 15.0923076923077 0.00092973729514598 0.0248988210571914 GO:0141047 molecular tag activity 3/247 15/18639 0.2 15.0923076923077 0.00092973729514598 0.0248988210571914 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 5/247 58/18639 0.0862068965517241 6.5053050397878 0.00101472040074615 0.0248988210571914 GO:0005096 GTPase activator activity 11/247 271/18639 0.040590405904059 3.06301447629861 0.0010219665359295 0.0248988210571914 GO:0016651 oxidoreductase activity, acting on NAD(P)H 6/247 88/18639 0.0681818181818182 5.14510489510489 0.00111587568039363 0.0260047549865645 GO:0023023 MHC protein complex binding 4/247 37/18639 0.108108108108108 8.15800415800416 0.00140982481623767 0.0314860875626413 GO:0019843 rRNA binding 5/247 65/18639 0.0769230769230769 5.80473372781065 0.00169711328773903 0.0350218684010058 GO:0015399 primary active transmembrane transporter activity 8/247 166/18639 0.0481927710843374 3.63670064874884 0.00169882197467565 0.0350218684010058 GO:0048027 mRNA 5'-UTR binding 3/247 24/18639 0.125 9.43269230769231 0.00378772960962643 0.0751934470651766 GO:0005080 protein kinase C binding 4/247 52/18639 0.0769230769230769 5.80473372781065 0.00495087951255065 0.0947739792402552 GO:0005246 calcium channel regulator activity 4/247 53/18639 0.0754716981132075 5.69521044992743 0.00530029759540451 0.0979641210736834 GO:0042277 peptide binding 9/247 249/18639 0.036144578313253 2.72752548656163 0.00612941522800106 0.109512218740286 GO:0031625 ubiquitin protein ligase binding 10/247 302/18639 0.033112582781457 2.49872643912379 0.00721401311839976 0.119180516058863 GO:0032395 MHC class II receptor activity 2/247 10/18639 0.2 15.0923076923077 0.00733760639914639 0.119180516058863 GO:0043208 glycosphingolipid binding 2/247 10/18639 0.2 15.0923076923077 0.00733760639914639 0.119180516058863 GO:0003823 antigen binding 7/247 174/18639 0.0402298850574713 3.03580901856764 0.0086334985244837 0.132366144902282 GO:0010854 adenylate cyclase regulator activity 2/247 11/18639 0.181818181818182 13.7202797202797 0.00889026346358613 0.132366144902282 GO:1990948 ubiquitin ligase inhibitor activity 2/247 11/18639 0.181818181818182 13.7202797202797 0.00889026346358613 0.132366144902282 GO:0019825 oxygen binding 3/247 34/18639 0.0882352941176471 6.65837104072398 0.0101625714281479 0.147219953661818 GO:0097371 MDM2/MDM4 family protein binding 2/247 12/18639 0.166666666666667 12.5769230769231 0.010575723217567 0.14917335906884 GO:0044389 ubiquitin-like protein ligase binding 10/247 322/18639 0.031055900621118 2.34352603917821 0.0110216569718354 0.151477131715481 GO:0030695 GTPase regulator activity 13/247 489/18639 0.0265848670756646 2.00613496932515 0.0138108641934054 0.182879036596034 GO:0060589 nucleoside-triphosphatase regulator activity 13/247 490/18639 0.026530612244898 2.00204081632653 0.014025079202087 0.182879036596034 GO:0071933 Arp2/3 complex binding 2/247 14/18639 0.142857142857143 10.7802197802198 0.014330073763122 0.182879036596034 GO:1902936 phosphatidylinositol bisphosphate binding 5/247 111/18639 0.045045045045045 3.3991683991684 0.0161632531805201 0.192973174255489 GO:0004129 cytochrome-c oxidase activity 2/247 15/18639 0.133333333333333 10.0615384615385 0.0163916639889645 0.192973174255489 GO:0055105 ubiquitin-protein transferase inhibitor activity 2/247 15/18639 0.133333333333333 10.0615384615385 0.0163916639889645 0.192973174255489 GO:0005200 structural constituent of cytoskeleton 5/247 112/18639 0.0446428571428571 3.36881868131868 0.0167414422581933 0.192973174255489 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 3/247 41/18639 0.0731707317073171 5.52157598499062 0.0169211552052387 0.192973174255489 GO:0140104 molecular carrier activity 8/247 249/18639 0.0321285140562249 2.42446709916589 0.0182542481098876 0.203148956684593 GO:0016675 oxidoreductase activity, acting on a heme group of donors 2/247 16/18639 0.125 9.43269230769231 0.0185714531297482 0.203148956684593 GO:0046332 SMAD binding 4/247 79/18639 0.0506329113924051 3.82083739045764 0.0208561462650795 0.223577887961652 GO:0030276 clathrin binding 3/247 46/18639 0.0652173913043478 4.92140468227425 0.022965470927617 0.235352803297648 GO:0035615 clathrin adaptor activity 2/247 18/18639 0.111111111111111 8.38461538461539 0.0232718256992077 0.235352803297648 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 2/247 18/18639 0.111111111111111 8.38461538461539 0.0232718256992077 0.235352803297648 GO:0010851 cyclase regulator activity 2/247 20/18639 0.1 7.54615384615385 0.0284042842186175 0.278111826567371 GO:0032813 tumor necrosis factor receptor superfamily binding 3/247 50/18639 0.06 4.52769230769231 0.0285375941440399 0.278111826567371 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 4/247 89/18639 0.0449438202247191 3.39152981849611 0.0306303762595093 0.287632718531609 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 4/247 89/18639 0.0449438202247191 3.39152981849611 0.0306303762595093 0.287632718531609 GO:0140312 cargo adaptor activity 2/247 21/18639 0.0952380952380952 7.18681318681319 0.0311244359605099 0.287632718531609 GO:0140793 histone H2AXY142 phosphatase activity 4/247 90/18639 0.0444444444444444 3.35384615384615 0.0317332133910498 0.288288175891571 GO:0005543 phospholipid binding 12/247 497/18639 0.0241448692152917 1.82200897693855 0.0337479281889336 0.30148149182114 GO:0017134 fibroblast growth factor binding 2/247 23/18639 0.0869565217391304 6.561872909699 0.0368569434900429 0.318634221139725 GO:0043274 phospholipase binding 2/247 23/18639 0.0869565217391304 6.561872909699 0.0368569434900429 0.318634221139725 GO:0004601 peroxidase activity 3/247 57/18639 0.0526315789473684 3.97165991902834 0.0398498342994818 0.339039860071782 GO:0004725 protein tyrosine phosphatase activity 4/247 98/18639 0.0408163265306122 3.08006279434851 0.0413899724570665 0.346641019327932 GO:0001786 phosphatidylserine binding 3/247 59/18639 0.0508474576271186 3.83702737940026 0.0434404816432076 0.35278936607211 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 3/247 59/18639 0.0508474576271186 3.83702737940026 0.0434404816432076 0.35278936607211 GO:0043548 phosphatidylinositol 3-kinase binding 2/247 26/18639 0.0769230769230769 5.80473372781065 0.0461412059854571 0.363701270708897 GO:0070412 R-SMAD binding 2/247 26/18639 0.0769230769230769 5.80473372781065 0.0461412059854571 0.363701270708897 GO:0015252 proton channel activity 2/247 27/18639 0.0740740740740741 5.58974358974359 0.0494071904269205 0.383800783606223 GO:0004857 enzyme inhibitor activity 10/247 416/18639 0.0240384615384615 1.81397928994083 0.0511963616682394 0.38734549689913 GO:0046625 sphingolipid binding 2/247 28/18639 0.0714285714285714 5.39010989010989 0.0527541441672322 0.38734549689913 GO:0051019 mitogen-activated protein kinase binding 2/247 28/18639 0.0714285714285714 5.39010989010989 0.0527541441672322 0.38734549689913 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 2/247 28/18639 0.0714285714285714 5.39010989010989 0.0527541441672322 0.38734549689913 GO:0003785 actin monomer binding 2/247 29/18639 0.0689655172413793 5.20424403183024 0.0561793671378128 0.401495210478235 GO:0051861 glycolipid binding 2/247 29/18639 0.0689655172413793 5.20424403183024 0.0561793671378128 0.401495210478235 GO:0001965 G-protein alpha-subunit binding 2/247 30/18639 0.0666666666666667 5.03076923076923 0.0596802160972559 0.42090257668591 GO:0099106 ion channel regulator activity 5/247 160/18639 0.03125 2.35817307692308 0.0620730739414408 0.432093086137821 GO:0005164 tumor necrosis factor receptor binding 2/247 31/18639 0.0645161290322581 4.86848635235732 0.0632541036094838 0.434669224803632 GO:0016247 channel regulator activity 5/247 168/18639 0.0297619047619048 2.24587912087912 0.0731747008095191 0.496476451062054 GO:0141108 transporter regulator activity 5/247 170/18639 0.0294117647058824 2.21945701357466 0.076109115706489 0.507060104728793 GO:0003725 double-stranded RNA binding 3/247 75/18639 0.04 3.01846153846154 0.0775726279622407 0.507060104728793 GO:0019003 GDP binding 3/247 75/18639 0.04 3.01846153846154 0.0775726279622407 0.507060104728793 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/247 36/18639 0.0555555555555556 4.19230769230769 0.0821323403432878 0.522701122685242 GO:0055106 ubiquitin-protein transferase regulator activity 2/247 36/18639 0.0555555555555556 4.19230769230769 0.0821323403432878 0.522701122685242 GO:0004721 phosphoprotein phosphatase activity 5/247 175/18639 0.0285714285714286 2.15604395604396 0.0837199549325154 0.522701122685242 GO:0022804 active transmembrane transporter activity 10/247 457/18639 0.0218818380743982 1.65123716546036 0.083866224908453 0.522701122685242 GO:0000146 microfilament motor activity 2/247 38/18639 0.0526315789473684 3.97165991902834 0.0901103135015753 0.53953221038102 GO:1901981 phosphatidylinositol phosphate binding 5/247 185/18639 0.027027027027027 2.03950103950104 0.100096150606444 0.53953221038102 GO:0051117 ATPase binding 3/247 84/18639 0.0357142857142857 2.69505494505495 0.100621267044008 0.53953221038102 GO:0042169 SH2 domain binding 2/247 41/18639 0.0487804878048781 3.68105065666041 0.102478801310028 0.53953221038102 GO:0042287 MHC protein binding 2/247 41/18639 0.0487804878048781 3.68105065666041 0.102478801310028 0.53953221038102 GO:0140318 protein transporter activity 2/247 41/18639 0.0487804878048781 3.68105065666041 0.102478801310028 0.53953221038102 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 3/247 86/18639 0.0348837209302326 2.63237924865832 0.106077372420396 0.53953221038102 GO:0016209 antioxidant activity 3/247 86/18639 0.0348837209302326 2.63237924865832 0.106077372420396 0.53953221038102 GO:0019838 growth factor binding 4/247 136/18639 0.0294117647058824 2.21945701357466 0.107064732013918 0.53953221038102 GO:0140789 histone phosphatase activity 4/247 136/18639 0.0294117647058824 2.21945701357466 0.107064732013918 0.53953221038102 GO:0004197 cysteine-type endopeptidase activity 3/247 88/18639 0.0340909090909091 2.57255244755245 0.111646957395379 0.53953221038102 GO:0004713 protein tyrosine kinase activity 4/247 140/18639 0.0285714285714286 2.15604395604396 0.11574255489759 0.53953221038102 GO:0020037 heme binding 4/247 142/18639 0.028169014084507 2.12567713976165 0.120193963293744 0.53953221038102 GO:0072341 modified amino acid binding 3/247 91/18639 0.032967032967033 2.48774302620456 0.120205777008444 0.53953221038102 GO:0043178 alcohol binding 3/247 92/18639 0.0326086956521739 2.46070234113712 0.123111313863798 0.53953221038102 GO:0003712 transcription coregulator activity 10/247 495/18639 0.0202020202020202 1.52447552447552 0.123456986308662 0.53953221038102 GO:0005031 tumor necrosis factor receptor activity 1/247 10/18639 0.1 7.54615384615385 0.124916665153 0.53953221038102 GO:0005522 profilin binding 1/247 10/18639 0.1 7.54615384615385 0.124916665153 0.53953221038102 GO:0005528 FK506 binding 1/247 10/18639 0.1 7.54615384615385 0.124916665153 0.53953221038102 GO:0008140 cAMP response element binding protein binding 1/247 10/18639 0.1 7.54615384615385 0.124916665153 0.53953221038102 GO:0008519 ammonium channel activity 1/247 10/18639 0.1 7.54615384615385 0.124916665153 0.53953221038102 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/247 10/18639 0.1 7.54615384615385 0.124916665153 0.53953221038102 GO:0016783 sulfurtransferase activity 1/247 10/18639 0.1 7.54615384615385 0.124916665153 0.53953221038102 GO:0031996 thioesterase binding 1/247 10/18639 0.1 7.54615384615385 0.124916665153 0.53953221038102 GO:0045322 unmethylated CpG binding 1/247 10/18639 0.1 7.54615384615385 0.124916665153 0.53953221038102 GO:0051864 histone H3K36 demethylase activity 1/247 10/18639 0.1 7.54615384615385 0.124916665153 0.53953221038102 GO:0070097 delta-catenin binding 1/247 10/18639 0.1 7.54615384615385 0.124916665153 0.53953221038102 GO:1990763 arrestin family protein binding 1/247 10/18639 0.1 7.54615384615385 0.124916665153 0.53953221038102 GO:0051020 GTPase binding 7/247 315/18639 0.0222222222222222 1.67692307692308 0.12645970443193 0.53953221038102 GO:0032266 phosphatidylinositol-3-phosphate binding 2/247 48/18639 0.0416666666666667 3.14423076923077 0.132928666506065 0.53953221038102 GO:0003714 transcription corepressor activity 5/247 204/18639 0.0245098039215686 1.84954751131222 0.135221198819034 0.53953221038102 GO:0003953 NAD+ nucleosidase activity 1/247 11/18639 0.0909090909090909 6.86013986013986 0.136519305321942 0.53953221038102 GO:0008271 secondary active sulfate transmembrane transporter activity 1/247 11/18639 0.0909090909090909 6.86013986013986 0.136519305321942 0.53953221038102 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 1/247 11/18639 0.0909090909090909 6.86013986013986 0.136519305321942 0.53953221038102 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/247 11/18639 0.0909090909090909 6.86013986013986 0.136519305321942 0.53953221038102 GO:0019864 IgG binding 1/247 11/18639 0.0909090909090909 6.86013986013986 0.136519305321942 0.53953221038102 GO:0032794 GTPase activating protein binding 1/247 11/18639 0.0909090909090909 6.86013986013986 0.136519305321942 0.53953221038102 GO:0050998 nitric-oxide synthase binding 1/247 11/18639 0.0909090909090909 6.86013986013986 0.136519305321942 0.53953221038102 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/247 11/18639 0.0909090909090909 6.86013986013986 0.136519305321942 0.53953221038102 GO:0000510 H3-H4 histone complex chaperone activity 4/247 151/18639 0.0264900662251656 1.99898115129903 0.14110520536611 0.53953221038102 GO:0140584 chromatin extrusion motor activity 4/247 151/18639 0.0264900662251656 1.99898115129903 0.14110520536611 0.53953221038102 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 4/247 151/18639 0.0264900662251656 1.99898115129903 0.14110520536611 0.53953221038102 GO:0140849 ATP-dependent H2AZ histone chaperone activity 4/247 151/18639 0.0264900662251656 1.99898115129903 0.14110520536611 0.53953221038102 GO:0005516 calmodulin binding 5/247 207/18639 0.0241545893719807 1.82274247491639 0.141215451370203 0.53953221038102 GO:0015616 DNA translocase activity 4/247 152/18639 0.0263157894736842 1.98582995951417 0.143513492234236 0.53953221038102 GO:0046906 tetrapyrrole binding 4/247 152/18639 0.0263157894736842 1.98582995951417 0.143513492234236 0.53953221038102 GO:0140674 ATP-dependent histone chaperone activity 4/247 152/18639 0.0263157894736842 1.98582995951417 0.143513492234236 0.53953221038102 GO:0061775 cohesin loader activity 4/247 153/18639 0.0261437908496732 1.97285067873303 0.145937975324498 0.53953221038102 GO:0004126 cytidine deaminase activity 1/247 12/18639 0.0833333333333333 6.28846153846154 0.147968721876884 0.53953221038102 GO:0005095 GTPase inhibitor activity 1/247 12/18639 0.0833333333333333 6.28846153846154 0.147968721876884 0.53953221038102 GO:0005165 neurotrophin receptor binding 1/247 12/18639 0.0833333333333333 6.28846153846154 0.147968721876884 0.53953221038102 GO:0005527 macrolide binding 1/247 12/18639 0.0833333333333333 6.28846153846154 0.147968721876884 0.53953221038102 GO:0010853 cyclase activator activity 1/247 12/18639 0.0833333333333333 6.28846153846154 0.147968721876884 0.53953221038102 GO:0017166 vinculin binding 1/247 12/18639 0.0833333333333333 6.28846153846154 0.147968721876884 0.53953221038102 GO:0035259 nuclear glucocorticoid receptor binding 1/247 12/18639 0.0833333333333333 6.28846153846154 0.147968721876884 0.53953221038102 GO:0035497 cAMP response element binding 1/247 12/18639 0.0833333333333333 6.28846153846154 0.147968721876884 0.53953221038102 GO:0045295 gamma-catenin binding 1/247 12/18639 0.0833333333333333 6.28846153846154 0.147968721876884 0.53953221038102 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/247 12/18639 0.0833333333333333 6.28846153846154 0.147968721876884 0.53953221038102 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/247 12/18639 0.0833333333333333 6.28846153846154 0.147968721876884 0.53953221038102 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/247 12/18639 0.0833333333333333 6.28846153846154 0.147968721876884 0.53953221038102 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/247 12/18639 0.0833333333333333 6.28846153846154 0.147968721876884 0.53953221038102 GO:0004386 helicase activity 4/247 155/18639 0.0258064516129032 1.94739454094293 0.150834672789677 0.540297940290861 GO:0140375 immune receptor activity 4/247 156/18639 0.0256410256410256 1.93491124260355 0.153306455012152 0.540297940290861 GO:0140658 ATP-dependent chromatin remodeler activity 4/247 158/18639 0.0253164556962025 1.91041869522882 0.158295796446291 0.540297940290861 GO:0005035 death receptor activity 1/247 13/18639 0.0769230769230769 5.80473372781065 0.159266930160366 0.540297940290861 GO:0019855 calcium channel inhibitor activity 1/247 13/18639 0.0769230769230769 5.80473372781065 0.159266930160366 0.540297940290861 GO:0031432 titin binding 1/247 13/18639 0.0769230769230769 5.80473372781065 0.159266930160366 0.540297940290861 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/247 13/18639 0.0769230769230769 5.80473372781065 0.159266930160366 0.540297940290861 GO:0045159 myosin II binding 1/247 13/18639 0.0769230769230769 5.80473372781065 0.159266930160366 0.540297940290861 GO:0051011 microtubule minus-end binding 1/247 13/18639 0.0769230769230769 5.80473372781065 0.159266930160366 0.540297940290861 GO:0089720 caspase binding 1/247 13/18639 0.0769230769230769 5.80473372781065 0.159266930160366 0.540297940290861 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/247 13/18639 0.0769230769230769 5.80473372781065 0.159266930160366 0.540297940290861 GO:0051287 NAD binding 2/247 54/18639 0.037037037037037 2.79487179487179 0.160418924288394 0.540783291940749 GO:0003689 DNA clamp loader activity 4/247 160/18639 0.025 1.88653846153846 0.163344706947639 0.546963668533557 GO:0008013 beta-catenin binding 3/247 106/18639 0.0283018867924528 2.13570391872279 0.166244544306515 0.546963668533557 GO:0005161 platelet-derived growth factor receptor binding 1/247 14/18639 0.0714285714285714 5.39010989010989 0.170415919114 0.546963668533557 GO:0016530 metallochaperone activity 1/247 14/18639 0.0714285714285714 5.39010989010989 0.170415919114 0.546963668533557 GO:0019763 immunoglobulin receptor activity 1/247 14/18639 0.0714285714285714 5.39010989010989 0.170415919114 0.546963668533557 GO:0042043 neurexin family protein binding 1/247 14/18639 0.0714285714285714 5.39010989010989 0.170415919114 0.546963668533557 GO:0061665 SUMO ligase activity 1/247 14/18639 0.0714285714285714 5.39010989010989 0.170415919114 0.546963668533557 GO:1901612 cardiolipin binding 1/247 14/18639 0.0714285714285714 5.39010989010989 0.170415919114 0.546963668533557 GO:0140713 histone chaperone activity 4/247 164/18639 0.024390243902439 1.84052532833021 0.173614121170823 0.552499211760744 GO:0031267 small GTPase binding 6/247 283/18639 0.0212014134275618 1.59989127480294 0.174523018374345 0.552499211760744 GO:0035091 phosphatidylinositol binding 6/247 284/18639 0.0211267605633803 1.59425785482123 0.176464371665266 0.552499211760744 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/247 15/18639 0.0666666666666667 5.03076923076923 0.181417651622931 0.552499211760744 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/247 15/18639 0.0666666666666667 5.03076923076923 0.181417651622931 0.552499211760744 GO:0015116 sulfate transmembrane transporter activity 1/247 15/18639 0.0666666666666667 5.03076923076923 0.181417651622931 0.552499211760744 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/247 15/18639 0.0666666666666667 5.03076923076923 0.181417651622931 0.552499211760744 GO:0050700 CARD domain binding 1/247 15/18639 0.0666666666666667 5.03076923076923 0.181417651622931 0.552499211760744 GO:0120283 protein serine/threonine kinase binding 1/247 15/18639 0.0666666666666667 5.03076923076923 0.181417651622931 0.552499211760744 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/247 16/18639 0.0625 4.71634615384615 0.19227406485581 0.560830256916437 GO:0004708 MAP kinase kinase activity 1/247 16/18639 0.0625 4.71634615384615 0.19227406485581 0.560830256916437 GO:0005159 insulin-like growth factor receptor binding 1/247 16/18639 0.0625 4.71634615384615 0.19227406485581 0.560830256916437 GO:0005521 lamin binding 1/247 16/18639 0.0625 4.71634615384615 0.19227406485581 0.560830256916437 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/247 16/18639 0.0625 4.71634615384615 0.19227406485581 0.560830256916437 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/247 16/18639 0.0625 4.71634615384615 0.19227406485581 0.560830256916437 GO:0070411 I-SMAD binding 1/247 16/18639 0.0625 4.71634615384615 0.19227406485581 0.560830256916437 GO:0001221 transcription coregulator binding 3/247 115/18639 0.0260869565217391 1.9685618729097 0.195993252109104 0.560830256916437 GO:0035401 histone H3Y41 kinase activity 3/247 115/18639 0.0260869565217391 1.9685618729097 0.195993252109104 0.560830256916437 GO:0140801 histone H2AXY142 kinase activity 3/247 115/18639 0.0260869565217391 1.9685618729097 0.195993252109104 0.560830256916437 GO:0001664 G protein-coupled receptor binding 6/247 297/18639 0.0202020202020202 1.52447552447552 0.20247554552155 0.560830256916437 GO:0004550 nucleoside diphosphate kinase activity 1/247 17/18639 0.0588235294117647 4.43891402714932 0.202987070600352 0.560830256916437 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/247 17/18639 0.0588235294117647 4.43891402714932 0.202987070600352 0.560830256916437 GO:0019198 transmembrane receptor protein phosphatase activity 1/247 17/18639 0.0588235294117647 4.43891402714932 0.202987070600352 0.560830256916437 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/247 17/18639 0.0588235294117647 4.43891402714932 0.202987070600352 0.560830256916437 GO:0046965 nuclear retinoid X receptor binding 1/247 17/18639 0.0588235294117647 4.43891402714932 0.202987070600352 0.560830256916437 GO:0070403 NAD+ binding 1/247 17/18639 0.0588235294117647 4.43891402714932 0.202987070600352 0.560830256916437 GO:0070492 oligosaccharide binding 1/247 17/18639 0.0588235294117647 4.43891402714932 0.202987070600352 0.560830256916437 GO:0015172 acidic amino acid transmembrane transporter activity 1/247 18/18639 0.0555555555555556 4.19230769230769 0.213558555594537 0.578118110094303 GO:0016854 racemase and epimerase activity 1/247 18/18639 0.0555555555555556 4.19230769230769 0.213558555594537 0.578118110094303 GO:0031690 adrenergic receptor binding 1/247 18/18639 0.0555555555555556 4.19230769230769 0.213558555594537 0.578118110094303 GO:1901611 phosphatidylglycerol binding 1/247 18/18639 0.0555555555555556 4.19230769230769 0.213558555594537 0.578118110094303 GO:0050840 extracellular matrix binding 2/247 67/18639 0.0298507462686567 2.25258323765786 0.222718273506559 0.594350716205328 GO:0030506 ankyrin binding 1/247 19/18639 0.0526315789473684 3.97165991902834 0.223990381853501 0.594350716205328 GO:0034987 immunoglobulin receptor binding 1/247 19/18639 0.0526315789473684 3.97165991902834 0.223990381853501 0.594350716205328 GO:0097001 ceramide binding 1/247 19/18639 0.0526315789473684 3.97165991902834 0.223990381853501 0.594350716205328 GO:0033218 amide binding 5/247 247/18639 0.0202429149797571 1.52756150731859 0.230749243153153 0.606649427187476 GO:0001614 purinergic nucleotide receptor activity 1/247 20/18639 0.05 3.77307692307692 0.234284386992178 0.606649427187476 GO:0016004 phospholipase activator activity 1/247 20/18639 0.05 3.77307692307692 0.234284386992178 0.606649427187476 GO:0016502 nucleotide receptor activity 1/247 20/18639 0.05 3.77307692307692 0.234284386992178 0.606649427187476 GO:0042288 MHC class I protein binding 1/247 20/18639 0.05 3.77307692307692 0.234284386992178 0.606649427187476 GO:0016782 transferase activity, transferring sulphur-containing groups 2/247 70/18639 0.0285714285714286 2.15604395604396 0.237396347296079 0.609495914587214 GO:0140597 protein carrier chaperone 4/247 188/18639 0.0212765957446809 1.60556464811784 0.239272516676862 0.609495914587214 GO:0005123 death receptor binding 1/247 21/18639 0.0476190476190476 3.59340659340659 0.244442384543762 0.609495914587214 GO:0008373 sialyltransferase activity 1/247 21/18639 0.0476190476190476 3.59340659340659 0.244442384543762 0.609495914587214 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/247 21/18639 0.0476190476190476 3.59340659340659 0.244442384543762 0.609495914587214 GO:0010314 phosphatidylinositol-5-phosphate binding 1/247 21/18639 0.0476190476190476 3.59340659340659 0.244442384543762 0.609495914587214 GO:0072542 protein phosphatase activator activity 1/247 21/18639 0.0476190476190476 3.59340659340659 0.244442384543762 0.609495914587214 GO:0035591 signaling adaptor activity 3/247 129/18639 0.0232558139534884 1.75491949910555 0.244480637381065 0.609495914587214 GO:0005518 collagen binding 2/247 72/18639 0.0277777777777778 2.09615384615385 0.247210613345149 0.613448559041665 GO:0019887 protein kinase regulator activity 5/247 255/18639 0.0196078431372549 1.47963800904977 0.250370742212608 0.614386775003907 GO:0008970 phospholipase A1 activity 1/247 22/18639 0.0454545454545455 3.43006993006993 0.254466164274006 0.614386775003907 GO:0015377 chloride:monoatomic cation symporter activity 1/247 22/18639 0.0454545454545455 3.43006993006993 0.254466164274006 0.614386775003907 GO:0033691 sialic acid binding 1/247 22/18639 0.0454545454545455 3.43006993006993 0.254466164274006 0.614386775003907 GO:0061133 endopeptidase activator activity 1/247 22/18639 0.0454545454545455 3.43006993006993 0.254466164274006 0.614386775003907 GO:0070034 telomerase RNA binding 1/247 22/18639 0.0454545454545455 3.43006993006993 0.254466164274006 0.614386775003907 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/247 23/18639 0.0434782608695652 3.2809364548495 0.264357492491459 0.620774950509208 GO:0016849 phosphorus-oxygen lyase activity 1/247 23/18639 0.0434782608695652 3.2809364548495 0.264357492491459 0.620774950509208 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/247 23/18639 0.0434782608695652 3.2809364548495 0.264357492491459 0.620774950509208 GO:0099186 structural constituent of postsynapse 1/247 23/18639 0.0434782608695652 3.2809364548495 0.264357492491459 0.620774950509208 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/247 23/18639 0.0434782608695652 3.2809364548495 0.264357492491459 0.620774950509208 GO:0002020 protease binding 3/247 136/18639 0.0220588235294118 1.664592760181 0.269410764131129 0.620774950509208 GO:0044325 transmembrane transporter binding 3/247 136/18639 0.0220588235294118 1.664592760181 0.269410764131129 0.620774950509208 GO:0003724 RNA helicase activity 2/247 77/18639 0.025974025974026 1.96003996003996 0.271790502024268 0.620774950509208 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/247 24/18639 0.0416666666666667 3.14423076923077 0.274118112353653 0.620774950509208 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/247 24/18639 0.0416666666666667 3.14423076923077 0.274118112353653 0.620774950509208 GO:0005315 phosphate transmembrane transporter activity 1/247 24/18639 0.0416666666666667 3.14423076923077 0.274118112353653 0.620774950509208 GO:0030552 cAMP binding 1/247 24/18639 0.0416666666666667 3.14423076923077 0.274118112353653 0.620774950509208 GO:0060229 lipase activator activity 1/247 24/18639 0.0416666666666667 3.14423076923077 0.274118112353653 0.620774950509208 GO:0070840 dynein complex binding 1/247 24/18639 0.0416666666666667 3.14423076923077 0.274118112353653 0.620774950509208 GO:0030295 protein kinase activator activity 3/247 139/18639 0.0215827338129496 1.62866629773105 0.280185836206992 0.620774950509208 GO:0008186 ATP-dependent activity, acting on RNA 2/247 79/18639 0.0253164556962025 1.91041869522882 0.281621209540302 0.620774950509208 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 5/247 268/18639 0.0186567164179104 1.40786452353617 0.283090167767214 0.620774950509208 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/247 25/18639 0.04 3.01846153846154 0.283749744169321 0.620774950509208 GO:0019211 phosphatase activator activity 1/247 25/18639 0.04 3.01846153846154 0.283749744169321 0.620774950509208 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/247 25/18639 0.04 3.01846153846154 0.283749744169321 0.620774950509208 GO:0019707 protein-cysteine S-acyltransferase activity 1/247 25/18639 0.04 3.01846153846154 0.283749744169321 0.620774950509208 GO:0042974 nuclear retinoic acid receptor binding 1/247 25/18639 0.04 3.01846153846154 0.283749744169321 0.620774950509208 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/247 25/18639 0.04 3.01846153846154 0.283749744169321 0.620774950509208 GO:0048306 calcium-dependent protein binding 2/247 80/18639 0.025 1.88653846153846 0.286532920275004 0.624315631168302 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/247 26/18639 0.0384615384615385 2.90236686390533 0.293254085696676 0.628736759733673 GO:0005112 Notch binding 1/247 26/18639 0.0384615384615385 2.90236686390533 0.293254085696676 0.628736759733673 GO:0019865 immunoglobulin binding 1/247 26/18639 0.0384615384615385 2.90236686390533 0.293254085696676 0.628736759733673 GO:0050750 low-density lipoprotein particle receptor binding 1/247 26/18639 0.0384615384615385 2.90236686390533 0.293254085696676 0.628736759733673 GO:0016791 phosphatase activity 5/247 273/18639 0.0183150183150183 1.38207945900254 0.295895227286066 0.631871879782197 GO:0005126 cytokine receptor binding 5/247 275/18639 0.0181818181818182 1.37202797202797 0.301045139304569 0.632987540450797 GO:0001540 amyloid-beta binding 2/247 83/18639 0.0240963855421687 1.81835032437442 0.301244079164224 0.632987540450797 GO:0001671 ATPase activator activity 1/247 27/18639 0.037037037037037 2.79487179487179 0.30263281243782 0.632987540450797 GO:0008320 protein transmembrane transporter activity 1/247 27/18639 0.037037037037037 2.79487179487179 0.30263281243782 0.632987540450797 GO:0008094 ATP-dependent activity, acting on DNA 4/247 210/18639 0.019047619047619 1.43736263736264 0.303633308095208 0.632987540450797 GO:0004860 protein kinase inhibitor activity 2/247 84/18639 0.0238095238095238 1.7967032967033 0.306137318484229 0.632987540450797 GO:0001217 DNA-binding transcription repressor activity 5/247 278/18639 0.0179856115107914 1.35722191477587 0.308796489164464 0.632987540450797 GO:0019789 SUMO transferase activity 1/247 28/18639 0.0357142857142857 2.69505494505495 0.311887577929323 0.632987540450797 GO:0045499 chemorepellent activity 1/247 28/18639 0.0357142857142857 2.69505494505495 0.311887577929323 0.632987540450797 GO:0051959 dynein light intermediate chain binding 1/247 28/18639 0.0357142857142857 2.69505494505495 0.311887577929323 0.632987540450797 GO:0097718 disordered domain specific binding 1/247 28/18639 0.0357142857142857 2.69505494505495 0.311887577929323 0.632987540450797 GO:0141052 histone H3 demethylase activity 1/247 28/18639 0.0357142857142857 2.69505494505495 0.311887577929323 0.632987540450797 GO:0019209 kinase activator activity 3/247 148/18639 0.0202702702702703 1.52962577962578 0.312708001865616 0.632987540450797 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 8/247 484/18639 0.0165289256198347 1.24729815638907 0.31295092951392 0.632987540450797 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 6/247 349/18639 0.0171919770773639 1.29733303945338 0.317452591492945 0.639653262154479 GO:0140297 DNA-binding transcription factor binding 8/247 488/18639 0.0163934426229508 1.23707440100883 0.320801921314556 0.639653262154479 GO:0016417 S-acyltransferase activity 1/247 29/18639 0.0344827586206897 2.60212201591512 0.32102001402902 0.639653262154479 GO:0043236 laminin binding 1/247 29/18639 0.0344827586206897 2.60212201591512 0.32102001402902 0.639653262154479 GO:0001216 DNA-binding transcription activator activity 8/247 491/18639 0.0162932790224033 1.22951590161366 0.326715020493218 0.644196577549556 GO:0141003 histone H2AX kinase activity 6/247 354/18639 0.0169491525423729 1.27900912646675 0.329110523458968 0.644196577549556 GO:0001968 fibronectin binding 1/247 30/18639 0.0333333333333333 2.51538461538462 0.330031731199081 0.644196577549556 GO:0032452 histone demethylase activity 1/247 30/18639 0.0333333333333333 2.51538461538462 0.330031731199081 0.644196577549556 GO:0098918 structural constituent of synapse 1/247 30/18639 0.0333333333333333 2.51538461538462 0.330031731199081 0.644196577549556 GO:0019207 kinase regulator activity 5/247 287/18639 0.0174216027874564 1.31466094880729 0.332207496580093 0.644196577549556 GO:0005506 iron ion binding 3/247 154/18639 0.0194805194805195 1.47002997002997 0.334458158649944 0.644196577549556 GO:0019210 kinase inhibitor activity 2/247 90/18639 0.0222222222222222 1.67692307692308 0.335338267960963 0.644196577549556 GO:0140996 histone H3 kinase activity 6/247 357/18639 0.0168067226890756 1.26826115061409 0.336132889585595 0.644196577549556 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/247 31/18639 0.032258064516129 2.43424317617866 0.338924318785401 0.644196577549556 GO:0047499 calcium-independent phospholipase A2 activity 1/247 31/18639 0.032258064516129 2.43424317617866 0.338924318785401 0.644196577549556 GO:0070325 lipoprotein particle receptor binding 1/247 31/18639 0.032258064516129 2.43424317617866 0.338924318785401 0.644196577549556 GO:0140457 protein demethylase activity 1/247 31/18639 0.032258064516129 2.43424317617866 0.338924318785401 0.644196577549556 GO:0035173 histone kinase activity 6/247 360/18639 0.0166666666666667 1.25769230769231 0.343172862654709 0.649966976618105 GO:0022884 macromolecule transmembrane transporter activity 1/247 32/18639 0.03125 2.35817307692308 0.347699345293355 0.651632339430902 GO:0047498 calcium-dependent phospholipase A2 activity 1/247 32/18639 0.03125 2.35817307692308 0.347699345293355 0.651632339430902 GO:0051059 NF-kappaB binding 1/247 32/18639 0.03125 2.35817307692308 0.347699345293355 0.651632339430902 GO:0051213 dioxygenase activity 2/247 93/18639 0.021505376344086 1.62282878411911 0.349808467137625 0.651813100764968 GO:0042578 phosphoric ester hydrolase activity 6/247 363/18639 0.0165289256198347 1.24729815638907 0.350227934739386 0.651813100764968 GO:0019239 deaminase activity 1/247 33/18639 0.0303030303030303 2.28671328671329 0.356358358659966 0.656385155469903 GO:0030296 protein tyrosine kinase activator activity 1/247 33/18639 0.0303030303030303 2.28671328671329 0.356358358659966 0.656385155469903 GO:0140311 protein sequestering activity 1/247 33/18639 0.0303030303030303 2.28671328671329 0.356358358659966 0.656385155469903 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/247 34/18639 0.0294117647058824 2.21945701357466 0.364902886522537 0.665265126449251 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/247 34/18639 0.0294117647058824 2.21945701357466 0.364902886522537 0.665265126449251 GO:0016831 carboxy-lyase activity 1/247 34/18639 0.0294117647058824 2.21945701357466 0.364902886522537 0.665265126449251 GO:0004623 phospholipase A2 activity 1/247 35/18639 0.0285714285714286 2.15604395604396 0.37333443648378 0.673761811297327 GO:0005154 epidermal growth factor receptor binding 1/247 35/18639 0.0285714285714286 2.15604395604396 0.37333443648378 0.673761811297327 GO:0043015 gamma-tubulin binding 1/247 35/18639 0.0285714285714286 2.15604395604396 0.37333443648378 0.673761811297327 GO:0016409 palmitoyltransferase activity 1/247 36/18639 0.0277777777777778 2.09615384615385 0.381654496373508 0.68646580555772 GO:0030280 structural constituent of skin epidermis 1/247 37/18639 0.027027027027027 2.03950103950104 0.389864534506914 0.69194500164141 GO:0030551 cyclic nucleotide binding 1/247 37/18639 0.027027027027027 2.03950103950104 0.389864534506914 0.69194500164141 GO:0042805 actinin binding 1/247 37/18639 0.027027027027027 2.03950103950104 0.389864534506914 0.69194500164141 GO:0043394 proteoglycan binding 1/247 37/18639 0.027027027027027 2.03950103950104 0.389864534506914 0.69194500164141 GO:0004722 protein serine/threonine phosphatase activity 2/247 103/18639 0.0194174757281553 1.46527259148618 0.397190762867501 0.702621283488385 GO:0008201 heparin binding 3/247 172/18639 0.0174418604651163 1.31618962432916 0.399289173746073 0.70400985897334 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/247 39/18639 0.0256410256410256 1.93491124260355 0.405960322718639 0.71109389861827 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/247 39/18639 0.0256410256410256 1.93491124260355 0.405960322718639 0.71109389861827 GO:0032451 demethylase activity 1/247 40/18639 0.025 1.88653846153846 0.413848914132 0.722550547149029 GO:0019888 protein phosphatase regulator activity 2/247 107/18639 0.0186915887850467 1.41049604601006 0.415704457794317 0.723433731745955 GO:0001530 lipopolysaccharide binding 1/247 41/18639 0.024390243902439 1.84052532833021 0.421633166952549 0.729017346730858 GO:0001727 lipid kinase activity 1/247 41/18639 0.024390243902439 1.84052532833021 0.421633166952549 0.729017346730858 GO:0019894 kinesin binding 1/247 42/18639 0.0238095238095238 1.7967032967033 0.429314455680515 0.731492999211936 GO:0035198 miRNA binding 1/247 42/18639 0.0238095238095238 1.7967032967033 0.429314455680515 0.731492999211936 GO:0048487 beta-tubulin binding 1/247 42/18639 0.0238095238095238 1.7967032967033 0.429314455680515 0.731492999211936 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/247 43/18639 0.0232558139534884 1.75491949910555 0.43689413678214 0.731492999211936 GO:0008200 ion channel inhibitor activity 1/247 43/18639 0.0232558139534884 1.75491949910555 0.43689413678214 0.731492999211936 GO:0003713 transcription coactivator activity 4/247 256/18639 0.015625 1.17908653846154 0.441141468173611 0.731492999211936 GO:0061135 endopeptidase regulator activity 3/247 184/18639 0.016304347826087 1.23035117056856 0.441581026170041 0.731492999211936 GO:0001223 transcription coactivator binding 1/247 44/18639 0.0227272727272727 1.71503496503496 0.444373548925332 0.731492999211936 GO:0016248 channel inhibitor activity 1/247 44/18639 0.0227272727272727 1.71503496503496 0.444373548925332 0.731492999211936 GO:0019205 nucleobase-containing compound kinase activity 1/247 44/18639 0.0227272727272727 1.71503496503496 0.444373548925332 0.731492999211936 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/247 45/18639 0.0222222222222222 1.67692307692308 0.451754013212261 0.731492999211936 GO:0008009 chemokine activity 1/247 45/18639 0.0222222222222222 1.67692307692308 0.451754013212261 0.731492999211936 GO:0141110 transporter inhibitor activity 1/247 45/18639 0.0222222222222222 1.67692307692308 0.451754013212261 0.731492999211936 GO:0017124 SH3 domain binding 2/247 115/18639 0.0173913043478261 1.3123745819398 0.451848437223213 0.731492999211936 GO:0008234 cysteine-type peptidase activity 3/247 187/18639 0.0160427807486631 1.21061291649527 0.45198131990889 0.731492999211936 GO:0019208 phosphatase regulator activity 2/247 117/18639 0.0170940170940171 1.28994082840237 0.460686497275621 0.731492999211936 GO:1990782 protein tyrosine kinase binding 2/247 117/18639 0.0170940170940171 1.28994082840237 0.460686497275621 0.731492999211936 GO:0019902 phosphatase binding 3/247 190/18639 0.0157894736842105 1.1914979757085 0.462302094811604 0.731492999211936 GO:0001784 phosphotyrosine residue binding 1/247 47/18639 0.0212765957446809 1.60556464811784 0.466223296171675 0.731492999211936 GO:0043495 protein-membrane adaptor activity 1/247 47/18639 0.0212765957446809 1.60556464811784 0.466223296171675 0.731492999211936 GO:0061749 forked DNA-dependent helicase activity 1/247 47/18639 0.0212765957446809 1.60556464811784 0.466223296171675 0.731492999211936 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/247 47/18639 0.0212765957446809 1.60556464811784 0.466223296171675 0.731492999211936 GO:0009378 four-way junction helicase activity 1/247 48/18639 0.0208333333333333 1.57211538461538 0.473314671270943 0.731492999211936 GO:0036121 double-stranded DNA helicase activity 1/247 48/18639 0.0208333333333333 1.57211538461538 0.473314671270943 0.731492999211936 GO:0043138 3'-5' DNA helicase activity 1/247 48/18639 0.0208333333333333 1.57211538461538 0.473314671270943 0.731492999211936 GO:0140693 molecular condensate scaffold activity 1/247 48/18639 0.0208333333333333 1.57211538461538 0.473314671270943 0.731492999211936 GO:0015108 chloride transmembrane transporter activity 2/247 121/18639 0.0165289256198347 1.24729815638907 0.478111136579277 0.731492999211936 GO:0001222 transcription corepressor binding 1/247 49/18639 0.0204081632653061 1.54003139717425 0.480312211811854 0.731492999211936 GO:0005004 GPI-linked ephrin receptor activity 1/247 49/18639 0.0204081632653061 1.54003139717425 0.480312211811854 0.731492999211936 GO:0005008 hepatocyte growth factor receptor activity 1/247 49/18639 0.0204081632653061 1.54003139717425 0.480312211811854 0.731492999211936 GO:0005009 insulin receptor activity 1/247 49/18639 0.0204081632653061 1.54003139717425 0.480312211811854 0.731492999211936 GO:0005011 macrophage colony-stimulating factor receptor activity 1/247 49/18639 0.0204081632653061 1.54003139717425 0.480312211811854 0.731492999211936 GO:0005018 platelet-derived growth factor alpha-receptor activity 1/247 49/18639 0.0204081632653061 1.54003139717425 0.480312211811854 0.731492999211936 GO:0005020 stem cell factor receptor activity 1/247 49/18639 0.0204081632653061 1.54003139717425 0.480312211811854 0.731492999211936 GO:0008288 boss receptor activity 1/247 49/18639 0.0204081632653061 1.54003139717425 0.480312211811854 0.731492999211936 GO:0016763 pentosyltransferase activity 1/247 49/18639 0.0204081632653061 1.54003139717425 0.480312211811854 0.731492999211936 GO:0035254 glutamate receptor binding 1/247 49/18639 0.0204081632653061 1.54003139717425 0.480312211811854 0.731492999211936 GO:0036332 placental growth factor receptor activity 1/247 49/18639 0.0204081632653061 1.54003139717425 0.480312211811854 0.731492999211936 GO:0038062 protein tyrosine kinase collagen receptor activity 1/247 49/18639 0.0204081632653061 1.54003139717425 0.480312211811854 0.731492999211936 GO:0060175 brain-derived neurotrophic factor receptor activity 1/247 49/18639 0.0204081632653061 1.54003139717425 0.480312211811854 0.731492999211936 GO:0060590 ATPase regulator activity 1/247 49/18639 0.0204081632653061 1.54003139717425 0.480312211811854 0.731492999211936 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 2/247 122/18639 0.0163934426229508 1.23707440100883 0.48241366670673 0.731492999211936 GO:0005006 epidermal growth factor receptor activity 1/247 50/18639 0.02 1.50923076923077 0.487217154452116 0.731492999211936 GO:0005007 fibroblast growth factor receptor activity 1/247 50/18639 0.02 1.50923076923077 0.487217154452116 0.731492999211936 GO:0005017 platelet-derived growth factor receptor activity 1/247 50/18639 0.02 1.50923076923077 0.487217154452116 0.731492999211936 GO:0005019 platelet-derived growth factor beta-receptor activity 1/247 50/18639 0.02 1.50923076923077 0.487217154452116 0.731492999211936 GO:0048020 CCR chemokine receptor binding 1/247 50/18639 0.02 1.50923076923077 0.487217154452116 0.731492999211936 GO:0005010 insulin-like growth factor receptor activity 1/247 51/18639 0.0196078431372549 1.47963800904977 0.494030719617016 0.731492999211936 GO:0005021 vascular endothelial growth factor receptor activity 1/247 51/18639 0.0196078431372549 1.47963800904977 0.494030719617016 0.731492999211936 GO:0005030 neurotrophin receptor activity 1/247 51/18639 0.0196078431372549 1.47963800904977 0.494030719617016 0.731492999211936 GO:0016830 carbon-carbon lyase activity 1/247 51/18639 0.0196078431372549 1.47963800904977 0.494030719617016 0.731492999211936 GO:0030544 Hsp70 protein binding 1/247 51/18639 0.0196078431372549 1.47963800904977 0.494030719617016 0.731492999211936 GO:0030159 signaling receptor complex adaptor activity 1/247 52/18639 0.0192307692307692 1.45118343195266 0.500754111711626 0.733046486148275 GO:0004864 protein phosphatase inhibitor activity 1/247 53/18639 0.0188679245283019 1.42380261248186 0.507388519330243 0.733046486148275 GO:0005003 ephrin receptor activity 1/247 53/18639 0.0188679245283019 1.42380261248186 0.507388519330243 0.733046486148275 GO:0005005 transmembrane-ephrin receptor activity 1/247 53/18639 0.0188679245283019 1.42380261248186 0.507388519330243 0.733046486148275 GO:0005544 calcium-dependent phospholipid binding 1/247 53/18639 0.0188679245283019 1.42380261248186 0.507388519330243 0.733046486148275 GO:0008146 sulfotransferase activity 1/247 53/18639 0.0188679245283019 1.42380261248186 0.507388519330243 0.733046486148275 GO:0017046 peptide hormone binding 1/247 53/18639 0.0188679245283019 1.42380261248186 0.507388519330243 0.733046486148275 GO:0038064 collagen receptor activity 1/247 53/18639 0.0188679245283019 1.42380261248186 0.507388519330243 0.733046486148275 GO:0140296 general transcription initiation factor binding 1/247 53/18639 0.0188679245283019 1.42380261248186 0.507388519330243 0.733046486148275 GO:0004674 protein serine/threonine kinase activity 6/247 433/18639 0.0138568129330254 1.04565642209984 0.513633992006339 0.734584591701935 GO:0015485 cholesterol binding 1/247 54/18639 0.0185185185185185 1.3974358974359 0.513935115463107 0.734584591701935 GO:0050661 NADP binding 1/247 54/18639 0.0185185185185185 1.3974358974359 0.513935115463107 0.734584591701935 GO:0140463 chromatin-protein adaptor activity 1/247 54/18639 0.0185185185185185 1.3974358974359 0.513935115463107 0.734584591701935 GO:0140313 molecular sequestering activity 1/247 55/18639 0.0181818181818182 1.37202797202797 0.520395057700428 0.741839763104866 GO:0106310 protein serine kinase activity 5/247 361/18639 0.0138504155124654 1.04517366290219 0.523145985393183 0.743783151646541 GO:0019212 phosphatase inhibitor activity 1/247 56/18639 0.0178571428571429 1.34752747252747 0.526769488433747 0.746953560318752 GO:0051087 protein-folding chaperone binding 2/247 134/18639 0.0149253731343284 1.12629161882893 0.532295374709499 0.751894502077133 GO:0016504 peptidase activator activity 1/247 57/18639 0.0175438596491228 1.32388663967611 0.533059535054684 0.751894502077133 GO:0017116 single-stranded DNA helicase activity 1/247 58/18639 0.0172413793103448 1.30106100795756 0.539266310151094 0.756666864505199 GO:0061980 regulatory RNA binding 1/247 58/18639 0.0172413793103448 1.30106100795756 0.539266310151094 0.756666864505199 GO:0015459 potassium channel regulator activity 1/247 59/18639 0.0169491525423729 1.27900912646675 0.54539091170067 0.759297477068985 GO:0031593 polyubiquitin modification-dependent protein binding 1/247 59/18639 0.0169491525423729 1.27900912646675 0.54539091170067 0.759297477068985 GO:0045309 protein phosphorylated amino acid binding 1/247 59/18639 0.0169491525423729 1.27900912646675 0.54539091170067 0.759297477068985 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/247 60/18639 0.0166666666666667 1.25769230769231 0.551434423262023 0.760726111508943 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/247 60/18639 0.0166666666666667 1.25769230769231 0.551434423262023 0.760726111508943 GO:0070851 growth factor receptor binding 2/247 139/18639 0.0143884892086331 1.0857775318207 0.552094136897349 0.760726111508943 GO:0140767 enzyme-substrate adaptor activity 2/247 139/18639 0.0143884892086331 1.0857775318207 0.552094136897349 0.760726111508943 GO:0015026 coreceptor activity 1/247 61/18639 0.0163934426229508 1.23707440100883 0.557397914163271 0.766064825619264 GO:0015179 L-amino acid transmembrane transporter activity 1/247 62/18639 0.0161290322580645 1.21712158808933 0.563282439688175 0.772172346989417 GO:0005507 copper ion binding 1/247 63/18639 0.0158730158730159 1.1978021978022 0.569089041259851 0.775228684614901 GO:1901682 sulfur compound transmembrane transporter activity 1/247 63/18639 0.0158730158730159 1.1978021978022 0.569089041259851 0.775228684614901 GO:0019903 protein phosphatase binding 2/247 144/18639 0.0138888888888889 1.04807692307692 0.571297258251653 0.775228684614901 GO:0019955 cytokine binding 2/247 144/18639 0.0138888888888889 1.04807692307692 0.571297258251653 0.775228684614901 GO:0061134 peptidase regulator activity 3/247 226/18639 0.0132743362831858 1.00170183798502 0.578510167399855 0.78101004763189 GO:0015631 tubulin binding 5/247 385/18639 0.012987012987013 0.98001998001998 0.58043772514757 0.78101004763189 GO:0038024 cargo receptor activity 1/247 65/18639 0.0153846153846154 1.16094674556213 0.580472570018279 0.78101004763189 GO:0008509 monoatomic anion transmembrane transporter activity 2/247 149/18639 0.0134228187919463 1.01290655653072 0.589898891118073 0.78101004763189 GO:0016500 protein-hormone receptor activity 1/247 67/18639 0.0149253731343284 1.12629161882893 0.591556561441755 0.78101004763189 GO:0032934 sterol binding 1/247 68/18639 0.0147058823529412 1.10972850678733 0.596988692032099 0.78101004763189 GO:1990841 promoter-specific chromatin binding 1/247 68/18639 0.0147058823529412 1.10972850678733 0.596988692032099 0.78101004763189 GO:0002039 p53 binding 1/247 69/18639 0.0144927536231884 1.09364548494983 0.602348866124398 0.78101004763189 GO:0003774 cytoskeletal motor activity 2/247 153/18639 0.0130718954248366 0.986425339366516 0.604345261973058 0.78101004763189 GO:0097110 scaffold protein binding 1/247 70/18639 0.0142857142857143 1.07802197802198 0.607638033063939 0.78101004763189 GO:0042379 chemokine receptor binding 1/247 72/18639 0.0138888888888889 1.04807692307692 0.618007080656321 0.78101004763189 GO:0004521 RNA endonuclease activity 1/247 73/18639 0.0136986301369863 1.03371970495258 0.623088798277794 0.78101004763189 GO:0043539 protein serine/threonine kinase activator activity 1/247 73/18639 0.0136986301369863 1.03371970495258 0.623088798277794 0.78101004763189 GO:0005539 glycosaminoglycan binding 3/247 242/18639 0.012396694214876 0.935473617291799 0.624851296460006 0.78101004763189 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 3/247 243/18639 0.0123456790123457 0.931623931623932 0.62762947450417 0.78101004763189 GO:0003678 DNA helicase activity 1/247 74/18639 0.0135135135135135 1.01975051975052 0.628103183003927 0.78101004763189 GO:0004866 endopeptidase inhibitor activity 2/247 161/18639 0.0124223602484472 0.937410415671285 0.632078886320205 0.78101004763189 GO:0005178 integrin binding 2/247 161/18639 0.0124223602484472 0.937410415671285 0.632078886320205 0.78101004763189 GO:0044183 protein folding chaperone 1/247 75/18639 0.0133333333333333 1.00615384615385 0.63305112341858 0.78101004763189 GO:0004676 3-phosphoinositide-dependent protein kinase activity 3/247 245/18639 0.0122448979591837 0.924018838304553 0.633143508261261 0.78101004763189 GO:0004711 ribosomal protein S6 kinase activity 3/247 245/18639 0.0122448979591837 0.924018838304553 0.633143508261261 0.78101004763189 GO:0035175 histone H3S10 kinase activity 3/247 245/18639 0.0122448979591837 0.924018838304553 0.633143508261261 0.78101004763189 GO:0035979 histone H2AXS139 kinase activity 3/247 245/18639 0.0122448979591837 0.924018838304553 0.633143508261261 0.78101004763189 GO:0044022 histone H3S28 kinase activity 3/247 245/18639 0.0122448979591837 0.924018838304553 0.633143508261261 0.78101004763189 GO:0044023 histone H4S1 kinase activity 3/247 245/18639 0.0122448979591837 0.924018838304553 0.633143508261261 0.78101004763189 GO:0044024 histone H2AS1 kinase activity 3/247 245/18639 0.0122448979591837 0.924018838304553 0.633143508261261 0.78101004763189 GO:0044025 histone H2BS14 kinase activity 3/247 245/18639 0.0122448979591837 0.924018838304553 0.633143508261261 0.78101004763189 GO:0072354 histone H3T3 kinase activity 3/247 245/18639 0.0122448979591837 0.924018838304553 0.633143508261261 0.78101004763189 GO:0072371 histone H2AS121 kinase activity 3/247 245/18639 0.0122448979591837 0.924018838304553 0.633143508261261 0.78101004763189 GO:0072518 Rho-dependent protein serine/threonine kinase activity 3/247 245/18639 0.0122448979591837 0.924018838304553 0.633143508261261 0.78101004763189 GO:0140823 histone H2BS36 kinase activity 3/247 245/18639 0.0122448979591837 0.924018838304553 0.633143508261261 0.78101004763189 GO:0140855 histone H3S57 kinase activity 3/247 245/18639 0.0122448979591837 0.924018838304553 0.633143508261261 0.78101004763189 GO:0140995 histone H2A kinase activity 3/247 245/18639 0.0122448979591837 0.924018838304553 0.633143508261261 0.78101004763189 GO:0140997 histone H4 kinase activity 3/247 245/18639 0.0122448979591837 0.924018838304553 0.633143508261261 0.78101004763189 GO:0140998 histone H2B kinase activity 3/247 245/18639 0.0122448979591837 0.924018838304553 0.633143508261261 0.78101004763189 GO:1990244 histone H2AT120 kinase activity 3/247 245/18639 0.0122448979591837 0.924018838304553 0.633143508261261 0.78101004763189 GO:0004677 DNA-dependent protein kinase activity 3/247 246/18639 0.0121951219512195 0.920262664165103 0.635879317871193 0.78101004763189 GO:0140857 histone H3T45 kinase activity 3/247 246/18639 0.0121951219512195 0.920262664165103 0.635879317871193 0.78101004763189 GO:0017022 myosin binding 1/247 76/18639 0.0131578947368421 0.992914979757085 0.637933496426316 0.78101004763189 GO:0035402 histone H3T11 kinase activity 3/247 247/18639 0.0121457489878543 0.916536904391155 0.638600961644756 0.78101004763189 GO:0035403 histone H3T6 kinase activity 3/247 247/18639 0.0121457489878543 0.916536904391155 0.638600961644756 0.78101004763189 GO:0004679 AMP-activated protein kinase activity 3/247 248/18639 0.0120967741935484 0.912841191066997 0.64130842110518 0.78101004763189 GO:0003924 GTPase activity 4/247 331/18639 0.0120845921450151 0.911921914943063 0.641953091749457 0.78101004763189 GO:0015103 inorganic anion transmembrane transporter activity 2/247 165/18639 0.0121212121212121 0.914685314685315 0.645369113241122 0.78101004763189 GO:0019199 transmembrane receptor protein kinase activity 1/247 78/18639 0.0128205128205128 0.967455621301775 0.647504990358145 0.78101004763189 GO:0016874 ligase activity 2/247 167/18639 0.0119760479041916 0.903730999539383 0.651871166580509 0.78101004763189 GO:0140097 catalytic activity, acting on DNA 4/247 336/18639 0.0119047619047619 0.898351648351648 0.653562266514122 0.78101004763189 GO:0000049 tRNA binding 1/247 80/18639 0.0125 0.943269230769231 0.656824452210127 0.78101004763189 GO:0030414 peptidase inhibitor activity 2/247 169/18639 0.0118343195266272 0.893035958124715 0.658278391861107 0.78101004763189 GO:0001618 virus receptor activity 1/247 81/18639 0.0123456790123457 0.931623931623932 0.661391743567641 0.78101004763189 GO:0033192 calmodulin-dependent protein phosphatase activity 1/247 81/18639 0.0123456790123457 0.931623931623932 0.661391743567641 0.78101004763189 GO:0140791 histone H2AXS140 phosphatase activity 1/247 81/18639 0.0123456790123457 0.931623931623932 0.661391743567641 0.78101004763189 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/247 81/18639 0.0123456790123457 0.931623931623932 0.661391743567641 0.78101004763189 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/247 81/18639 0.0123456790123457 0.931623931623932 0.661391743567641 0.78101004763189 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/247 81/18639 0.0123456790123457 0.931623931623932 0.661391743567641 0.78101004763189 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/247 81/18639 0.0123456790123457 0.931623931623932 0.661391743567641 0.78101004763189 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/247 81/18639 0.0123456790123457 0.931623931623932 0.661391743567641 0.78101004763189 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/247 81/18639 0.0123456790123457 0.931623931623932 0.661391743567641 0.78101004763189 GO:0005261 monoatomic cation channel activity 4/247 341/18639 0.0117302052785924 0.88517933679224 0.664919044133126 0.78101004763189 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/247 82/18639 0.0121951219512195 0.920262664165103 0.665898492104056 0.78101004763189 GO:0033549 MAP kinase phosphatase activity 1/247 82/18639 0.0121951219512195 0.920262664165103 0.665898492104056 0.78101004763189 GO:0140272 exogenous protein binding 1/247 82/18639 0.0121951219512195 0.920262664165103 0.665898492104056 0.78101004763189 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/247 83/18639 0.0120481927710843 0.90917516218721 0.670345497139907 0.782799970516319 GO:0030165 PDZ domain binding 1/247 83/18639 0.0120481927710843 0.90917516218721 0.670345497139907 0.782799970516319 GO:0017018 myosin phosphatase activity 1/247 84/18639 0.0119047619047619 0.898351648351648 0.674733547485156 0.786211264026182 GO:0008081 phosphoric diester hydrolase activity 1/247 87/18639 0.0114942528735632 0.86737400530504 0.687551703696367 0.799409356141546 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 2/247 181/18639 0.0110497237569061 0.833829154271143 0.694759111784695 0.806040874278347 GO:1901681 sulfur compound binding 3/247 275/18639 0.0109090909090909 0.823216783216783 0.709025581224332 0.816929756394551 GO:0008017 microtubule binding 3/247 276/18639 0.0108695652173913 0.820234113712375 0.711334873341215 0.816929756394551 GO:0005216 monoatomic ion channel activity 5/247 448/18639 0.0111607142857143 0.84220467032967 0.71137396243819 0.816929756394551 GO:0051219 phosphoprotein binding 1/247 93/18639 0.010752688172043 0.811414392059553 0.711698164537291 0.816929756394551 GO:0031406 carboxylic acid binding 2/247 187/18639 0.0106951871657754 0.807075277663513 0.711765291485551 0.816929756394551 GO:0016410 N-acyltransferase activity 1/247 94/18639 0.0106382978723404 0.80278232405892 0.715537836345729 0.817757527252262 GO:0042562 hormone binding 1/247 94/18639 0.0106382978723404 0.80278232405892 0.715537836345729 0.817757527252262 GO:0043177 organic acid binding 2/247 189/18639 0.0105820105820106 0.798534798534799 0.717255809053367 0.817976837558733 GO:0004896 cytokine receptor activity 1/247 96/18639 0.0104166666666667 0.786057692307692 0.723065052788319 0.821928020080081 GO:0046982 protein heterodimerization activity 4/247 369/18639 0.010840108401084 0.818011257035647 0.723787360966041 0.821928020080081 GO:0015171 amino acid transmembrane transporter activity 1/247 102/18639 0.00980392156862745 0.739819004524887 0.744477033941023 0.84347121740433 GO:0016829 lyase activity 2/247 200/18639 0.01 0.754615384615385 0.74590551688368 0.84347121740433 GO:0000149 SNARE binding 1/247 106/18639 0.00943396226415094 0.711901306240929 0.757827367020062 0.853351825047801 GO:0004497 monooxygenase activity 1/247 106/18639 0.00943396226415094 0.711901306240929 0.757827367020062 0.853351825047801 GO:0005496 steroid binding 1/247 108/18639 0.00925925925925926 0.698717948717949 0.764239672339914 0.858768269128289 GO:0004620 phospholipase activity 1/247 109/18639 0.00917431192660551 0.692307692307692 0.767382125576762 0.86049543788524 GO:0019001 guanyl nucleotide binding 4/247 400/18639 0.01 0.754615384615385 0.779652793416438 0.870612285981689 GO:0032561 guanyl ribonucleotide binding 4/247 400/18639 0.01 0.754615384615385 0.779652793416438 0.870612285981689 GO:0015294 solute:monoatomic cation symporter activity 1/247 116/18639 0.00862068965517241 0.65053050397878 0.788241568395047 0.878373140664751 GO:0003697 single-stranded DNA binding 1/247 121/18639 0.00826446280991736 0.623649078194533 0.80199021340926 0.889242060320415 GO:0004540 RNA nuclease activity 1/247 121/18639 0.00826446280991736 0.623649078194533 0.80199021340926 0.889242060320415 GO:0008528 G protein-coupled peptide receptor activity 1/247 122/18639 0.00819672131147541 0.618537200504414 0.804631341894405 0.889242060320415 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/247 122/18639 0.00819672131147541 0.618537200504414 0.804631341894405 0.889242060320415 GO:0016887 ATP hydrolysis activity 4/247 417/18639 0.00959232613908873 0.723851687880465 0.806294774379319 0.889246911661142 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 2/247 229/18639 0.00873362445414847 0.659052737655358 0.809768108693891 0.889972035193115 GO:0000287 magnesium ion binding 2/247 230/18639 0.00869565217391304 0.6561872909699 0.811692172776826 0.889972035193115 GO:0004519 endonuclease activity 1/247 127/18639 0.0078740157480315 0.594185342216838 0.817319864054119 0.889972035193115 GO:0042826 histone deacetylase binding 1/247 127/18639 0.0078740157480315 0.594185342216838 0.817319864054119 0.889972035193115 GO:0005125 cytokine activity 2/247 234/18639 0.00854700854700855 0.644970414201184 0.819216450075886 0.889972035193115 GO:0001653 peptide receptor activity 1/247 128/18639 0.0078125 0.589543269230769 0.819757309688228 0.889972035193115 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 1/247 128/18639 0.0078125 0.589543269230769 0.819757309688228 0.889972035193115 GO:0016298 lipase activity 1/247 130/18639 0.00769230769230769 0.580473372781065 0.824535453165114 0.889972035193115 GO:0016798 hydrolase activity, acting on glycosyl bonds 1/247 130/18639 0.00769230769230769 0.580473372781065 0.824535453165114 0.889972035193115 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/247 130/18639 0.00769230769230769 0.580473372781065 0.824535453165114 0.889972035193115 GO:0005262 calcium channel activity 1/247 131/18639 0.00763358778625954 0.576042278332355 0.826877002847334 0.889972035193115 GO:0031072 heat shock protein binding 1/247 131/18639 0.00763358778625954 0.576042278332355 0.826877002847334 0.889972035193115 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/247 132/18639 0.00757575757575758 0.571678321678322 0.829187429705812 0.89067026517498 GO:0015297 antiporter activity 1/247 135/18639 0.00740740740740741 0.558974358974359 0.835936066360756 0.89612346313873 GO:0016779 nucleotidyltransferase activity 1/247 136/18639 0.00735294117647059 0.554864253393665 0.838126068068975 0.896677789391159 GO:0016922 nuclear receptor binding 1/247 137/18639 0.0072992700729927 0.550814149354295 0.840286953394974 0.897198818764355 GO:0015293 symporter activity 1/247 146/18639 0.00684931506849315 0.516859852476291 0.858486652933124 0.914808838910844 GO:0015085 calcium ion transmembrane transporter activity 1/247 147/18639 0.00680272108843537 0.513343799058085 0.860376762527323 0.915003858560804 GO:0016757 glycosyltransferase activity 2/247 267/18639 0.00749063670411985 0.565254969749352 0.871695902394212 0.925205947887719 GO:0061659 ubiquitin-like protein ligase activity 3/247 372/18639 0.00806451612903226 0.608560794044665 0.873574145530285 0.925367079059748 GO:0005525 GTP binding 3/247 378/18639 0.00793650793650794 0.598901098901099 0.880346173320838 0.930701279881596 GO:0015079 potassium ion transmembrane transporter activity 1/247 160/18639 0.00625 0.471634615384615 0.882777043402663 0.931434045794936 GO:0008083 growth factor activity 1/247 162/18639 0.00617283950617284 0.465811965811966 0.885889910510338 0.932882106156269 GO:0030246 carbohydrate binding 2/247 280/18639 0.00714285714285714 0.539010989010989 0.888231215987473 0.933439622728618 GO:0140098 catalytic activity, acting on RNA 3/247 387/18639 0.00775193798449612 0.584973166368515 0.889902326892395 0.933439622728618 GO:0005201 extracellular matrix structural constituent 1/247 168/18639 0.00595238095238095 0.449175824175824 0.894743111645847 0.936482425393928 GO:0015291 secondary active transmembrane transporter activity 2/247 287/18639 0.00696864111498258 0.525864379522916 0.896297545199785 0.936482425393928 GO:0140030 modification-dependent protein binding 1/247 173/18639 0.00578034682080925 0.436193863939529 0.901595755375503 0.93851414608238 GO:0022832 voltage-gated channel activity 1/247 175/18639 0.00571428571428571 0.431208791208791 0.904210717041784 0.93851414608238 GO:0004252 serine-type endopeptidase activity 1/247 176/18639 0.00568181818181818 0.428758741258741 0.905492126968705 0.93851414608238 GO:0043021 ribonucleoprotein complex binding 1/247 177/18639 0.00564971751412429 0.426336375488918 0.906756463459998 0.93851414608238 GO:0004175 endopeptidase activity 3/247 405/18639 0.00740740740740741 0.558974358974359 0.906996879982598 0.93851414608238 GO:0016853 isomerase activity 1/247 180/18639 0.00555555555555556 0.419230769230769 0.910449283116923 0.940271321292237 GO:0015276 ligand-gated monoatomic ion channel activity 1/247 186/18639 0.00537634408602151 0.405707196029777 0.917403601580602 0.943561205725229 GO:0022834 ligand-gated channel activity 1/247 188/18639 0.00531914893617021 0.40139116202946 0.91960002670556 0.943561205725229 GO:0046943 carboxylic acid transmembrane transporter activity 1/247 188/18639 0.00531914893617021 0.40139116202946 0.91960002670556 0.943561205725229 GO:0005342 organic acid transmembrane transporter activity 1/247 189/18639 0.00529100529100529 0.399267399267399 0.920676325735625 0.943561205725229 GO:0008236 serine-type peptidase activity 1/247 194/18639 0.00515463917525773 0.388977002379064 0.925846334960905 0.945327736132263 GO:0022836 gated channel activity 2/247 318/18639 0.00628930817610063 0.474600870827286 0.925927353487758 0.945327736132263 GO:0017171 serine hydrolase activity 1/247 198/18639 0.00505050505050505 0.381118881118881 0.929739585484712 0.947415243003432 GO:0004518 nuclease activity 1/247 209/18639 0.00478468899521531 0.36105999263894 0.939427700051033 0.955471057357408 GO:0061630 ubiquitin protein ligase activity 2/247 353/18639 0.0056657223796034 0.427544127260841 0.949759098593817 0.964149387966451 GO:0005085 guanyl-nucleotide exchange factor activity 1/247 230/18639 0.00434782608695652 0.32809364548495 0.954380442747996 0.965628833310424 GO:0019787 ubiquitin-like protein transferase activity 3/247 479/18639 0.00626304801670146 0.472619238798779 0.954819555325606 0.965628833310424 GO:0016755 aminoacyltransferase activity 3/247 496/18639 0.00604838709677419 0.456420595533499 0.96194235448426 0.971000192097106 GO:0003730 mRNA 3'-UTR binding 1/247 262/18639 0.00381679389312977 0.288021139166177 0.97040196342271 0.977698218786791 GO:0008514 organic anion transmembrane transporter activity 1/247 269/18639 0.00371747211895911 0.28052616528453 0.973077309351855 0.978554292331321 GO:0004842 ubiquitin-protein transferase activity 2/247 449/18639 0.0044543429844098 0.336131574438924 0.983296152346716 0.98532889355061 GO:0046873 metal ion transmembrane transporter activity 2/247 450/18639 0.00444444444444444 0.335384615384615 0.983490593376076 0.98532889355061 GO:0045182 translation regulator activity 1/247 356/18639 0.00280898876404494 0.211970613656007 0.991731428004448 0.991731428004448