ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003779	actin binding	144/2272	443/18639	0.325056433408578	2.66669316122468	4.71118947742966e-30	5.93138755208394e-27
GO:0005201	extracellular matrix structural constituent	69/2272	168/18639	0.410714285714286	3.3694117831992	2.40345652990288e-21	1.51297588557386e-18
GO:0051015	actin filament binding	71/2272	209/18639	0.339712918660287	2.78693181818182	1.42417052499562e-16	5.97676896989829e-14
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	29/2272	68/18639	0.426470588235294	3.4986731048053	2.95162663037439e-10	9.29024481910339e-08
GO:0019838	growth factor binding	44/2272	136/18639	0.323529411764706	2.6541658036454	4.95822373359658e-10	1.24848073611962e-07
GO:0045296	cadherin binding	79/2272	334/18639	0.236526946107784	1.94041626254533	3.51078787064573e-09	7.36680321523829e-07
GO:0005178	integrin binding	46/2272	161/18639	0.285714285714286	2.34393863179074	1.73132592588624e-08	2.80543607363396e-06
GO:0009055	electron transfer activity	37/2272	116/18639	0.318965517241379	2.61672459324915	1.78264404996598e-08	2.80543607363396e-06
GO:0022853	active monoatomic ion transmembrane transporter activity	37/2272	118/18639	0.313559322033898	2.57237332895679	2.9658087465435e-08	4.14883690210919e-06
GO:0003954	NADH dehydrogenase activity	20/2272	44/18639	0.454545454545455	3.72899327784891	4.59291166837659e-08	5.78247579048613e-06
GO:0008137	NADH dehydrogenase (ubiquinone) activity	19/2272	41/18639	0.463414634146341	3.80175412229474	6.77226669157636e-08	7.75116705881331e-06
GO:0015399	primary active transmembrane transporter activity	44/2272	166/18639	0.265060240963855	2.17449728491431	3.72124158551401e-07	3.90420263013512e-05
GO:0015078	proton transmembrane transporter activity	46/2272	185/18639	0.248648648648649	2.03986010658546	1.45918743562068e-06	0.000131681785981907
GO:0030020	extracellular matrix structural constituent conferring tensile strength	18/2272	44/18639	0.409090909090909	3.35609395006402	1.4642930927297e-06	0.000131681785981907
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	21/2272	58/18639	0.362068965517241	2.97033602476931	2.1557007169988e-06	0.000180819433619328
GO:0005518	collagen binding	24/2272	72/18639	0.333333333333333	2.73459507042254	2.29794355671902e-06	0.000180819433619328
GO:0005096	GTPase activator activity	60/2272	271/18639	0.22140221402214	1.81633620913674	2.70209965530699e-06	0.000200114321531265
GO:0005525	GTP binding	76/2272	378/18639	0.201058201058201	1.64943829644534	6.52684157689117e-06	0.000456516308072555
GO:0050840	extracellular matrix binding	22/2272	67/18639	0.328358208955224	2.69378021862518	7.9192553258121e-06	0.000524754866063023
GO:0016651	oxidoreductase activity, acting on NAD(P)H	26/2272	88/18639	0.295454545454545	2.42384563060179	1.0909022795774e-05	0.000686722984993971
GO:0019001	guanyl nucleotide binding	78/2272	400/18639	0.195	1.59973811619718	1.57442814928921e-05	0.000901002290888686
GO:0032561	guanyl ribonucleotide binding	78/2272	400/18639	0.195	1.59973811619718	1.57442814928921e-05	0.000901002290888686
GO:1901981	phosphatidylinositol phosphate binding	43/2272	185/18639	0.232432432432432	1.90682575180815	1.94659353111124e-05	0.00106554837203002
GO:0060589	nucleoside-triphosphatase regulator activity	91/2272	490/18639	0.185714285714286	1.52356011066398	2.38609136705154e-05	0.00118902439225348
GO:0022804	active transmembrane transporter activity	86/2272	457/18639	0.188183807439825	1.54381953647487	2.39864074918278e-05	0.00118902439225348
GO:0005543	phospholipid binding	92/2272	497/18639	0.185110663983903	1.51860812763907	2.45549119925263e-05	0.00118902439225348
GO:0030695	GTPase regulator activity	90/2272	489/18639	0.184049079754601	1.50989911863821	3.74249775954586e-05	0.00174511284417342
GO:0031267	small GTPase binding	58/2272	283/18639	0.204946996466431	1.68134113870502	4.41350793108703e-05	0.00198450231615663
GO:0050431	transforming growth factor beta binding	11/2272	24/18639	0.458333333333333	3.76006822183099	4.69528522075937e-05	0.00203840141135726
GO:0140297	DNA-binding transcription factor binding	89/2272	488/18639	0.182377049180328	1.4961821389402	5.81811071046667e-05	0.00244166712815918
GO:0044548	S100 protein binding	8/2272	14/18639	0.571428571428571	4.68787726358149	7.31249012012444e-05	0.0029698145358828
GO:0048407	platelet-derived growth factor binding	7/2272	11/18639	0.636363636363636	5.22059058898848	8.35789076131618e-05	0.00318866196015063
GO:0097493	structural molecule activity conferring elasticity	7/2272	11/18639	0.636363636363636	5.22059058898848	8.35789076131618e-05	0.00318866196015063
GO:0035615	clathrin adaptor activity	9/2272	18/18639	0.5	4.1018926056338	0.000101042558708274	0.00374154651216816
GO:1902936	phosphatidylinositol bisphosphate binding	28/2272	111/18639	0.252252252252252	2.06942329653597	0.000119647277710586	0.00430388350393222
GO:0046332	SMAD binding	22/2272	79/18639	0.278481012658228	2.2845984132644	0.000134188731247092	0.00469287812889136
GO:0001786	phosphatidylserine binding	18/2272	59/18639	0.305084745762712	2.50284972547147	0.000151944977991427	0.00517023587273533
GO:0003924	GTPase activity	63/2272	331/18639	0.190332326283988	1.56144552359474	0.000201891237762091	0.00668897548269665
GO:0051020	GTPase binding	60/2272	315/18639	0.19047619047619	1.56262575452716	0.000276661449748262	0.00893119910854005
GO:0005200	structural constituent of cytoskeleton	27/2272	112/18639	0.241071428571429	1.97769822057344	0.000347593586080218	0.0109405081218748
GO:0002020	protease binding	31/2272	136/18639	0.227941176470588	1.86998045256835	0.000383164129238199	0.0117659424075827
GO:0140312	cargo adaptor activity	9/2272	21/18639	0.428571428571429	3.51590794768612	0.00043368027640018	0.0130000825711387
GO:0001968	fibronectin binding	11/2272	30/18639	0.366666666666667	3.00805457746479	0.000511919609268838	0.0149885299551039
GO:0004721	phosphoprotein phosphatase activity	37/2272	175/18639	0.211428571428571	1.73451458752515	0.000534918737142014	0.0153059702286772
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	9/2272	23/18639	0.391304347826087	3.21017682180037	0.000960418867217106	0.0248757859772757
GO:0035091	phosphatidylinositol binding	53/2272	284/18639	0.186619718309859	1.53098808520135	0.000992436652247486	0.0248757859772757
GO:0005080	protein kinase C binding	15/2272	52/18639	0.288461538461538	2.36647650325027	0.00101334577344855	0.0248757859772757
GO:0042805	actinin binding	12/2272	37/18639	0.324324324324324	2.66068709554625	0.00102801948946952	0.0248757859772757
GO:0004129	cytochrome-c oxidase activity	7/2272	15/18639	0.466666666666667	3.82843309859155	0.00104463088421628	0.0248757859772757
GO:0051371	muscle alpha-actinin binding	7/2272	15/18639	0.466666666666667	3.82843309859155	0.00104463088421628	0.0248757859772757
GO:0003756	protein disulfide isomerase activity	8/2272	19/18639	0.421052631578947	3.45422535211268	0.00104719353200604	0.0248757859772757
GO:0005346	purine ribonucleotide transmembrane transporter activity	8/2272	19/18639	0.421052631578947	3.45422535211268	0.00104719353200604	0.0248757859772757
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	8/2272	19/18639	0.421052631578947	3.45422535211268	0.00104719353200604	0.0248757859772757
GO:0072341	modified amino acid binding	22/2272	91/18639	0.241758241758242	1.98333268843832	0.00113273032568964	0.0264093977785788
GO:0051393	alpha-actinin binding	10/2272	28/18639	0.357142857142857	2.92992328973843	0.00116125520683218	0.0265821873709402
GO:0008194	UDP-glycosyltransferase activity	31/2272	145/18639	0.213793103448276	1.75391270033997	0.00119808898415629	0.026911877097217
GO:0141003	histone H2AX kinase activity	63/2272	354/18639	0.177966101694915	1.45999567319169	0.00124949374912142	0.026911877097217
GO:1901505	carbohydrate derivative transmembrane transporter activity	15/2272	53/18639	0.283018867924528	2.32182600318895	0.0012563576604765	0.026911877097217
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	21/2272	86/18639	0.244186046511628	2.00324987717	0.00126767379499867	0.026911877097217
GO:0071889	14-3-3 protein binding	11/2272	33/18639	0.333333333333333	2.73459507042254	0.0012825358425997	0.026911877097217
GO:0004725	protein tyrosine phosphatase activity	23/2272	98/18639	0.23469387755102	1.92537816182811	0.00136000775944929	0.0274152684196965
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	9/2272	24/18639	0.375	3.07641945422535	0.00137185219256623	0.0274152684196965
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	9/2272	24/18639	0.375	3.07641945422535	0.00137185219256623	0.0274152684196965
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	62/2272	349/18639	0.177650429799427	1.45740596876387	0.00142074562876746	0.0279487304159098
GO:0000287	magnesium ion binding	44/2272	230/18639	0.191304347826087	1.56941977954685	0.00154124776878754	0.0292690635079311
GO:0140996	histone H3 kinase activity	63/2272	357/18639	0.176470588235294	1.4477268019884	0.00154684009390101	0.0292690635079311
GO:0031543	peptidyl-proline dioxygenase activity	6/2272	12/18639	0.5	4.1018926056338	0.00156341351560026	0.0292690635079311
GO:0003785	actin monomer binding	10/2272	29/18639	0.344827586206897	2.82889145216124	0.00158085489955466	0.0292690635079311
GO:0016675	oxidoreductase activity, acting on a heme group of donors	7/2272	16/18639	0.4375	3.58915602992958	0.00166271242882694	0.0303384775056974
GO:0008376	acetylgalactosaminyltransferase activity	11/2272	34/18639	0.323529411764706	2.6541658036454	0.00168960992256883	0.0303888413216307
GO:0035173	histone kinase activity	63/2272	360/18639	0.175	1.43566241197183	0.00190492994376696	0.0337789690028536
GO:0035402	histone H3T11 kinase activity	46/2272	247/18639	0.186234817813765	1.52783044420368	0.00214696599149395	0.037210888191198
GO:0016757	glycosyltransferase activity	49/2272	267/18639	0.183520599250936	1.5055635780978	0.00215758128511315	0.037210888191198
GO:0004679	AMP-activated protein kinase activity	46/2272	248/18639	0.185483870967742	1.52166983757383	0.00233156031858263	0.0396680329877774
GO:0004112	cyclic-nucleotide phosphodiesterase activity	9/2272	26/18639	0.346153846153846	2.83977180390032	0.00261429244279861	0.0424143825483639
GO:0004676	3-phosphoinositide-dependent protein kinase activity	45/2272	245/18639	0.183673469387755	1.50681769186548	0.00313423910821959	0.0424143825483639
GO:0004711	ribosomal protein S6 kinase activity	45/2272	245/18639	0.183673469387755	1.50681769186548	0.00313423910821959	0.0424143825483639
GO:0035175	histone H3S10 kinase activity	45/2272	245/18639	0.183673469387755	1.50681769186548	0.00313423910821959	0.0424143825483639
GO:0035979	histone H2AXS139 kinase activity	45/2272	245/18639	0.183673469387755	1.50681769186548	0.00313423910821959	0.0424143825483639
GO:0044022	histone H3S28 kinase activity	45/2272	245/18639	0.183673469387755	1.50681769186548	0.00313423910821959	0.0424143825483639
GO:0044023	histone H4S1 kinase activity	45/2272	245/18639	0.183673469387755	1.50681769186548	0.00313423910821959	0.0424143825483639
GO:0044024	histone H2AS1 kinase activity	45/2272	245/18639	0.183673469387755	1.50681769186548	0.00313423910821959	0.0424143825483639
GO:0044025	histone H2BS14 kinase activity	45/2272	245/18639	0.183673469387755	1.50681769186548	0.00313423910821959	0.0424143825483639
GO:0072354	histone H3T3 kinase activity	45/2272	245/18639	0.183673469387755	1.50681769186548	0.00313423910821959	0.0424143825483639
GO:0072371	histone H2AS121 kinase activity	45/2272	245/18639	0.183673469387755	1.50681769186548	0.00313423910821959	0.0424143825483639
GO:0072518	Rho-dependent protein serine/threonine kinase activity	45/2272	245/18639	0.183673469387755	1.50681769186548	0.00313423910821959	0.0424143825483639
GO:0140823	histone H2BS36 kinase activity	45/2272	245/18639	0.183673469387755	1.50681769186548	0.00313423910821959	0.0424143825483639
GO:0140855	histone H3S57 kinase activity	45/2272	245/18639	0.183673469387755	1.50681769186548	0.00313423910821959	0.0424143825483639
GO:0140995	histone H2A kinase activity	45/2272	245/18639	0.183673469387755	1.50681769186548	0.00313423910821959	0.0424143825483639
GO:0140997	histone H4 kinase activity	45/2272	245/18639	0.183673469387755	1.50681769186548	0.00313423910821959	0.0424143825483639
GO:0140998	histone H2B kinase activity	45/2272	245/18639	0.183673469387755	1.50681769186548	0.00313423910821959	0.0424143825483639
GO:1990244	histone H2AT120 kinase activity	45/2272	245/18639	0.183673469387755	1.50681769186548	0.00313423910821959	0.0424143825483639
GO:0030021	extracellular matrix structural constituent conferring compression resistance	8/2272	22/18639	0.363636363636364	2.98319462227913	0.00316676088923447	0.0424143825483639
GO:0061133	endopeptidase activator activity	8/2272	22/18639	0.363636363636364	2.98319462227913	0.00316676088923447	0.0424143825483639
GO:0004677	DNA-dependent protein kinase activity	45/2272	246/18639	0.182926829268293	1.50069241669529	0.00339372210843682	0.0441877220582562
GO:0140857	histone H3T45 kinase activity	45/2272	246/18639	0.182926829268293	1.50069241669529	0.00339372210843682	0.0441877220582562
GO:0019208	phosphatase regulator activity	25/2272	117/18639	0.213675213675214	1.75294555796316	0.00342448726398911	0.0441877220582562
GO:0008307	structural constituent of muscle	12/2272	42/18639	0.285714285714286	2.34393863179074	0.0034395526304282	0.0441877220582562
GO:0043394	proteoglycan binding	11/2272	37/18639	0.297297297297297	2.4389631709174	0.0035771008771076	0.0454906061038229
GO:0042578	phosphoric ester hydrolase activity	62/2272	363/18639	0.170798898071625	1.4011974741008	0.00366248479076783	0.0457660811184606
GO:0035403	histone H3T6 kinase activity	45/2272	247/18639	0.182186234817814	1.49461673889491	0.00367146480775578	0.0457660811184606
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	7/2272	18/18639	0.388888888888889	3.19036091549296	0.00371054482902347	0.0457997641151034
GO:0005522	profilin binding	5/2272	10/18639	0.5	4.1018926056338	0.00397296507035431	0.0476377430816769
GO:0008239	dipeptidyl-peptidase activity	5/2272	10/18639	0.5	4.1018926056338	0.00397296507035431	0.0476377430816769
GO:0043121	neurotrophin binding	5/2272	10/18639	0.5	4.1018926056338	0.00397296507035431	0.0476377430816769
GO:0005347	ATP transmembrane transporter activity	6/2272	14/18639	0.428571428571429	3.51590794768612	0.00409259664418863	0.0486092375003159
GO:0005539	glycosaminoglycan binding	44/2272	242/18639	0.181818181818182	1.49159731113956	0.00419345695532216	0.0493417038014075
GO:0019955	cytokine binding	29/2272	144/18639	0.201388888888889	1.65215118838028	0.00426792402841698	0.0497529291831202
GO:0000295	adenine nucleotide transmembrane transporter activity	8/2272	23/18639	0.347826086956522	2.85349050826699	0.0043434766343104	0.0501691475467596
GO:0000146	microfilament motor activity	11/2272	38/18639	0.289473684210526	2.37477992957746	0.00448938814313103	0.0509349964506688
GO:0019888	protein phosphatase regulator activity	23/2272	107/18639	0.214953271028037	1.76343046597341	0.004502836363056	0.0509349964506688
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	44/2272	243/18639	0.181069958847737	1.4854590505999	0.00453115139195783	0.0509349964506688
GO:0004857	enzyme inhibitor activity	69/2272	416/18639	0.165865384615385	1.36072398936891	0.00468706500153393	0.0522213702383293
GO:0004860	protein kinase inhibitor activity	19/2272	84/18639	0.226190476190476	1.85561808350101	0.00525805818082728	0.0571343579436071
GO:0019210	kinase inhibitor activity	20/2272	90/18639	0.222222222222222	1.82306338028169	0.00526156511650327	0.0571343579436071
GO:0043395	heparan sulfate proteoglycan binding	7/2272	19/18639	0.368421052631579	3.02244718309859	0.00526416641895029	0.0571343579436071
GO:0017124	SH3 domain binding	24/2272	115/18639	0.208695652173913	1.7120943049602	0.00557120151680533	0.0598394784175385
GO:0016791	phosphatase activity	48/2272	273/18639	0.175824175824176	1.44242377340969	0.00560846580879233	0.0598394784175385
GO:0070300	phosphatidic acid binding	8/2272	24/18639	0.333333333333333	2.73459507042254	0.00582928885518249	0.0616728963754181
GO:0031005	filamin binding	6/2272	15/18639	0.4	3.28151408450704	0.00612457381750353	0.0642569869686412
GO:0031625	ubiquitin protein ligase binding	52/2272	302/18639	0.172185430463576	1.41257228803283	0.00622622826876596	0.06478364785435
GO:0005516	calmodulin binding	38/2272	207/18639	0.183574879227053	1.50600887936314	0.00630359870780243	0.0650510719108464
GO:0000099	sulfur amino acid transmembrane transporter activity	5/2272	11/18639	0.454545454545455	3.72899327784891	0.00655759074332585	0.0671220060637987
GO:0015932	nucleobase-containing compound transmembrane transporter activity	14/2272	57/18639	0.245614035087719	2.01496478873239	0.00732430700889742	0.0737704201936148
GO:0016504	peptidase activator activity	14/2272	57/18639	0.245614035087719	2.01496478873239	0.00732430700889742	0.0737704201936148
GO:0016922	nuclear receptor binding	27/2272	137/18639	0.197080291970803	1.61680438470237	0.00764591976645486	0.0760534040765465
GO:0019211	phosphatase activator activity	8/2272	25/18639	0.32	2.62521126760563	0.00767178897356744	0.0760534040765465
GO:0001618	virus receptor activity	18/2272	81/18639	0.222222222222222	1.82306338028169	0.00785758095941337	0.0772866752179799
GO:0004674	protein serine/threonine kinase activity	70/2272	433/18639	0.161662817551963	1.32624703184465	0.00809622035494117	0.0790166002083018
GO:0016758	hexosyltransferase activity	36/2272	197/18639	0.182741116751269	1.49916887109459	0.0082593691326929	0.0799888133696951
GO:0140272	exogenous protein binding	18/2272	82/18639	0.219512195121951	1.80083090003435	0.00894915481404254	0.0858240003135494
GO:0098631	cell adhesion mediator activity	17/2272	76/18639	0.223684210526316	1.83505721830986	0.00899822719729032	0.0858240003135494
GO:0061134	peptidase regulator activity	40/2272	226/18639	0.176991150442478	1.45199738252524	0.00961788550617114	0.0910444951298456
GO:0015216	purine nucleotide transmembrane transporter activity	8/2272	26/18639	0.307692307692308	2.52424160346696	0.00991956520946469	0.0924469386410131
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	19/2272	89/18639	0.213483146067416	1.75136987656275	0.00998632538139617	0.0924469386410131
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	19/2272	89/18639	0.213483146067416	1.75136987656275	0.00998632538139617	0.0924469386410131
GO:0017166	vinculin binding	5/2272	12/18639	0.416666666666667	3.41824383802817	0.0101248601917013	0.093045248039065
GO:1901681	sulfur compound binding	47/2272	275/18639	0.170909090909091	1.40210147247119	0.01022981393782	0.0933285199109807
GO:0016853	isomerase activity	33/2272	180/18639	0.183333333333333	1.50402728873239	0.0105673214676545	0.0957140843724962
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	25/2272	128/18639	0.1953125	1.6023017990757	0.0111846511601013	0.100095828757674
GO:0140793	histone H2AXY142 phosphatase activity	19/2272	90/18639	0.211111111111111	1.73191021126761	0.0112506978466492	0.100095828757674
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	13/2272	54/18639	0.240740740740741	1.9749853286385	0.0113691052520631	0.100095828757674
GO:0051287	NAD binding	13/2272	54/18639	0.240740740740741	1.9749853286385	0.0113691052520631	0.100095828757674
GO:0140789	histone phosphatase activity	26/2272	136/18639	0.191176470588235	1.5683707021541	0.012881892839427	0.112627104755824
GO:0044389	ubiquitin-like protein ligase binding	53/2272	322/18639	0.164596273291925	1.35031247266206	0.013851403431264	0.120268392551458
GO:0061135	endopeptidase regulator activity	33/2272	184/18639	0.179347826086957	1.47133104332517	0.0144812394390635	0.124875893519047
GO:0005172	vascular endothelial growth factor receptor binding	5/2272	13/18639	0.384615384615385	3.15530200433369	0.0148245322947309	0.126966572510654
GO:0048306	calcium-dependent protein binding	17/2272	80/18639	0.2125	1.74330435739437	0.0149555271751169	0.127223031847785
GO:0015605	organophosphate ester transmembrane transporter activity	12/2272	50/18639	0.24	1.96890845070423	0.0150683531879255	0.127322527943612
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	8/2272	28/18639	0.285714285714286	2.34393863179074	0.015825039123479	0.131945193751391
GO:0097718	disordered domain specific binding	8/2272	28/18639	0.285714285714286	2.34393863179074	0.015825039123479	0.131945193751391
GO:0098641	cadherin binding involved in cell-cell adhesion	6/2272	18/18639	0.333333333333333	2.73459507042254	0.016477529659574	0.136481643693445
GO:0106310	protein serine kinase activity	58/2272	361/18639	0.160664819944598	1.31805967383247	0.0166973562572766	0.137398506718374
GO:0008017	microtubule binding	46/2272	276/18639	0.166666666666667	1.36729753521127	0.0168461475343079	0.137722725621387
GO:0005507	copper ion binding	14/2272	63/18639	0.222222222222222	1.82306338028169	0.0177743115895709	0.144373279298515
GO:0015035	protein-disulfide reductase activity	9/2272	34/18639	0.264705882352941	2.1715902029826	0.0178933350266389	0.14440838973422
GO:0004713	protein tyrosine kinase activity	26/2272	140/18639	0.185714285714286	1.52356011066398	0.018355797721789	0.14719712950148
GO:0015036	disulfide oxidoreductase activity	10/2272	40/18639	0.25	2.0509463028169	0.0192354758206363	0.152311094705542
GO:0071949	FAD binding	10/2272	40/18639	0.25	2.0509463028169	0.0192354758206363	0.152311094705542
GO:0051087	protein-folding chaperone binding	25/2272	134/18639	0.186567164179104	1.53055694240067	0.0193872096887315	0.152553106238206
GO:0043236	laminin binding	8/2272	29/18639	0.275862068965517	2.26311316172899	0.0195770153914134	0.153089828433475
GO:0030276	clathrin binding	11/2272	46/18639	0.239130434782609	1.96177472443356	0.0200227746337983	0.155609094221926
GO:0001221	transcription coregulator binding	22/2272	115/18639	0.191304347826087	1.56941977954685	0.0207592607544591	0.157653487517911
GO:0008191	metalloendopeptidase inhibitor activity	5/2272	14/18639	0.357142857142857	2.92992328973843	0.0207867187672544	0.157653487517911
GO:0016530	metallochaperone activity	5/2272	14/18639	0.357142857142857	2.92992328973843	0.0207867187672544	0.157653487517911
GO:0034236	protein kinase A catalytic subunit binding	5/2272	14/18639	0.357142857142857	2.92992328973843	0.0207867187672544	0.157653487517911
GO:0035035	histone acetyltransferase binding	7/2272	24/18639	0.291666666666667	2.39277068661972	0.0209719553910482	0.158105939145687
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	17/2272	83/18639	0.204819277108434	1.68029335652469	0.0211576675424987	0.158556568071464
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	23/2272	122/18639	0.188524590163934	1.54661524474717	0.0215913961639689	0.160849513434538
GO:0019902	phosphatase binding	33/2272	190/18639	0.173684210526316	1.42486795774648	0.0224641260026351	0.166366674337162
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	10/2272	41/18639	0.24390243902439	2.00092322226039	0.0227415259701509	0.167436147347485
GO:0044325	transmembrane transporter binding	25/2272	136/18639	0.183823529411765	1.50804875207125	0.0229810899831633	0.168216234237224
GO:0016860	intramolecular oxidoreductase activity	12/2272	53/18639	0.226415094339623	1.85746080255116	0.0235256609856315	0.171206977924335
GO:0015215	nucleotide transmembrane transporter activity	8/2272	30/18639	0.266666666666667	2.18767605633803	0.0239211224653083	0.172493203813514
GO:0004222	metalloendopeptidase activity	21/2272	110/18639	0.190909090909091	1.56617717669654	0.0239764183219738	0.172493203813514
GO:0019199	transmembrane receptor protein kinase activity	16/2272	78/18639	0.205128205128205	1.68282773564464	0.0245029037400729	0.175279294367908
GO:0001094	TFIID-class transcription factor complex binding	4/2272	10/18639	0.4	3.28151408450704	0.0252026792069446	0.177263536991862
GO:0005528	FK506 binding	4/2272	10/18639	0.4	3.28151408450704	0.0252026792069446	0.177263536991862
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	4/2272	10/18639	0.4	3.28151408450704	0.0252026792069446	0.177263536991862
GO:0003712	transcription coregulator activity	75/2272	495/18639	0.151515151515152	1.24299775928297	0.0268585924968824	0.185133919437607
GO:0003925	G protein activity	12/2272	54/18639	0.222222222222222	1.82306338028169	0.0269989626237939	0.185133919437607
GO:0008201	heparin binding	30/2272	172/18639	0.174418604651163	1.43089276940714	0.0270323224587985	0.185133919437607
GO:0016879	ligase activity, forming carbon-nitrogen bonds	11/2272	48/18639	0.229166666666667	1.88003411091549	0.0270569032379028	0.185133919437607
GO:0032266	phosphatidylinositol-3-phosphate binding	11/2272	48/18639	0.229166666666667	1.88003411091549	0.0270569032379028	0.185133919437607
GO:0031418	L-ascorbic acid binding	6/2272	20/18639	0.3	2.46113556338028	0.0278219124617219	0.189339393455718
GO:0015026	coreceptor activity	13/2272	61/18639	0.213114754098361	1.74834766797506	0.0301989558676585	0.204411212028935
GO:0033192	calmodulin-dependent protein phosphatase activity	16/2272	81/18639	0.197530864197531	1.62050078247261	0.0338195140630854	0.218947169751736
GO:0140791	histone H2AXS140 phosphatase activity	16/2272	81/18639	0.197530864197531	1.62050078247261	0.0338195140630854	0.218947169751736
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	16/2272	81/18639	0.197530864197531	1.62050078247261	0.0338195140630854	0.218947169751736
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	16/2272	81/18639	0.197530864197531	1.62050078247261	0.0338195140630854	0.218947169751736
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	16/2272	81/18639	0.197530864197531	1.62050078247261	0.0338195140630854	0.218947169751736
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	16/2272	81/18639	0.197530864197531	1.62050078247261	0.0338195140630854	0.218947169751736
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	16/2272	81/18639	0.197530864197531	1.62050078247261	0.0338195140630854	0.218947169751736
GO:1990439	MAP kinase serine/threonine phosphatase activity	16/2272	81/18639	0.197530864197531	1.62050078247261	0.0338195140630854	0.218947169751736
GO:0072542	protein phosphatase activator activity	6/2272	21/18639	0.285714285714286	2.34393863179074	0.0350461745324894	0.218947169751736
GO:0003725	double-stranded RNA binding	15/2272	75/18639	0.2	1.64075704225352	0.0353771642126872	0.218947169751736
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	4/2272	11/18639	0.363636363636364	2.98319462227913	0.0358570154718696	0.218947169751736
GO:0015217	ADP transmembrane transporter activity	4/2272	11/18639	0.363636363636364	2.98319462227913	0.0358570154718696	0.218947169751736
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	4/2272	11/18639	0.363636363636364	2.98319462227913	0.0358570154718696	0.218947169751736
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	4/2272	11/18639	0.363636363636364	2.98319462227913	0.0358570154718696	0.218947169751736
GO:0019215	intermediate filament binding	4/2272	11/18639	0.363636363636364	2.98319462227913	0.0358570154718696	0.218947169751736
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	4/2272	11/18639	0.363636363636364	2.98319462227913	0.0358570154718696	0.218947169751736
GO:0034713	type I transforming growth factor beta receptor binding	4/2272	11/18639	0.363636363636364	2.98319462227913	0.0358570154718696	0.218947169751736
GO:0035252	UDP-xylosyltransferase activity	4/2272	11/18639	0.363636363636364	2.98319462227913	0.0358570154718696	0.218947169751736
GO:0042285	xylosyltransferase activity	4/2272	11/18639	0.363636363636364	2.98319462227913	0.0358570154718696	0.218947169751736
GO:0048185	activin binding	4/2272	11/18639	0.363636363636364	2.98319462227913	0.0358570154718696	0.218947169751736
GO:0001223	transcription coactivator binding	10/2272	44/18639	0.227272727272727	1.86449663892446	0.0359984623817389	0.218947169751736
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	5/2272	16/18639	0.3125	2.56368287852113	0.0368978369655026	0.22016292293634
GO:0005024	transforming growth factor beta receptor activity	5/2272	16/18639	0.3125	2.56368287852113	0.0368978369655026	0.22016292293634
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	5/2272	16/18639	0.3125	2.56368287852113	0.0368978369655026	0.22016292293634
GO:0030275	LRR domain binding	5/2272	16/18639	0.3125	2.56368287852113	0.0368978369655026	0.22016292293634
GO:0004867	serine-type endopeptidase inhibitor activity	18/2272	95/18639	0.189473684210526	1.5544014084507	0.0371262946760199	0.22023777284935
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	16/2272	82/18639	0.195121951219512	1.60073857780831	0.0374351734628761	0.22023777284935
GO:0033549	MAP kinase phosphatase activity	16/2272	82/18639	0.195121951219512	1.60073857780831	0.0374351734628761	0.22023777284935
GO:0015252	proton channel activity	7/2272	27/18639	0.259259259259259	2.12690727699531	0.0389469034686871	0.228065820777103
GO:0097110	scaffold protein binding	14/2272	70/18639	0.2	1.64075704225352	0.0411397691601759	0.239791524873432
GO:0004722	protein serine/threonine phosphatase activity	19/2272	103/18639	0.184466019417476	1.51331960207849	0.0419335827496475	0.243292076874683
GO:0019903	protein phosphatase binding	25/2272	144/18639	0.173611111111111	1.42426826584507	0.0427097109517417	0.246658376551572
GO:0008093	cytoskeletal anchor activity	6/2272	22/18639	0.272727272727273	2.23739596670935	0.0433739816311473	0.248217467607339
GO:0016881	acid-amino acid ligase activity	6/2272	22/18639	0.272727272727273	2.23739596670935	0.0433739816311473	0.248217467607339
GO:0017018	myosin phosphatase activity	16/2272	84/18639	0.19047619047619	1.56262575452716	0.0454901255420737	0.25666265367343
GO:0051117	ATPase binding	16/2272	84/18639	0.19047619047619	1.56262575452716	0.0454901255420737	0.25666265367343
GO:0030159	signaling receptor complex adaptor activity	11/2272	52/18639	0.211538461538462	1.73541610238353	0.0461513228514715	0.25666265367343
GO:0046875	ephrin receptor binding	7/2272	28/18639	0.25	2.0509463028169	0.0466541915837564	0.25666265367343
GO:0051019	mitogen-activated protein kinase binding	7/2272	28/18639	0.25	2.0509463028169	0.0466541915837564	0.25666265367343
GO:0005085	guanyl-nucleotide exchange factor activity	37/2272	230/18639	0.160869565217391	1.31973936007348	0.0469724039329666	0.25666265367343
GO:0160215	deacylase activity	13/2272	65/18639	0.2	1.64075704225352	0.047919939523271	0.25666265367343
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	23/2272	132/18639	0.174242424242424	1.42944742317542	0.0485603575307075	0.25666265367343
GO:0004859	phospholipase inhibitor activity	4/2272	12/18639	0.333333333333333	2.73459507042254	0.0487230931119538	0.25666265367343
GO:0005025	transforming growth factor beta receptor activity, type I	4/2272	12/18639	0.333333333333333	2.73459507042254	0.0487230931119538	0.25666265367343
GO:0005026	transforming growth factor beta receptor activity, type II	4/2272	12/18639	0.333333333333333	2.73459507042254	0.0487230931119538	0.25666265367343
GO:0005527	macrolide binding	4/2272	12/18639	0.333333333333333	2.73459507042254	0.0487230931119538	0.25666265367343
GO:0008179	adenylate cyclase binding	4/2272	12/18639	0.333333333333333	2.73459507042254	0.0487230931119538	0.25666265367343
GO:0016361	activin receptor activity, type I	4/2272	12/18639	0.333333333333333	2.73459507042254	0.0487230931119538	0.25666265367343
GO:0016362	activin receptor activity, type II	4/2272	12/18639	0.333333333333333	2.73459507042254	0.0487230931119538	0.25666265367343
GO:0017002	activin receptor activity	4/2272	12/18639	0.333333333333333	2.73459507042254	0.0487230931119538	0.25666265367343
GO:0035259	nuclear glucocorticoid receptor binding	4/2272	12/18639	0.333333333333333	2.73459507042254	0.0487230931119538	0.25666265367343
GO:0035497	cAMP response element binding	4/2272	12/18639	0.333333333333333	2.73459507042254	0.0487230931119538	0.25666265367343
GO:0141221	histone deacetylase activity, hydrolytic mechanism	4/2272	12/18639	0.333333333333333	2.73459507042254	0.0487230931119538	0.25666265367343
GO:0045309	protein phosphorylated amino acid binding	12/2272	59/18639	0.203389830508475	1.66856648364765	0.0500660786046162	0.262638304013382
GO:0015631	tubulin binding	58/2272	385/18639	0.150649350649351	1.23589491494421	0.0511225749235048	0.26706772543026
GO:0005158	insulin receptor binding	6/2272	23/18639	0.260869565217391	2.14011788120024	0.0528393830357568	0.274895798520735
GO:0003714	transcription corepressor activity	33/2272	204/18639	0.161764705882353	1.3270829018227	0.0543258823028519	0.281466196787204
GO:0140318	protein transporter activity	9/2272	41/18639	0.219512195121951	1.80083090003435	0.0551690039438209	0.284018358491652
GO:0051861	glycolipid binding	7/2272	29/18639	0.241379310344828	1.98022401651287	0.0552696567358655	0.284018358491652
GO:0005154	epidermal growth factor receptor binding	8/2272	35/18639	0.228571428571429	1.8751509054326	0.05579563238741	0.285208430276751
GO:0051213	dioxygenase activity	17/2272	93/18639	0.182795698924731	1.49961665152204	0.0561808504437127	0.285208430276751
GO:0051219	phosphoprotein binding	17/2272	93/18639	0.182795698924731	1.49961665152204	0.0561808504437127	0.285208430276751
GO:0003713	transcription coactivator activity	40/2272	256/18639	0.15625	1.28184143926056	0.058898942933678	0.294959791074737
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	5/2272	18/18639	0.277777777777778	2.27882922535211	0.0589879372270783	0.294959791074737
GO:0008525	phosphatidylcholine transporter activity	5/2272	18/18639	0.277777777777778	2.27882922535211	0.0589879372270783	0.294959791074737
GO:0016500	protein-hormone receptor activity	13/2272	67/18639	0.194029850746269	1.5917792200967	0.0590388144168656	0.294959791074737
GO:0016859	cis-trans isomerase activity	9/2272	42/18639	0.214285714285714	1.75795397384306	0.0629367431831315	0.310594796577181
GO:0005338	nucleotide-sugar transmembrane transporter activity	4/2272	13/18639	0.307692307692308	2.52424160346696	0.0637891201418306	0.310594796577181
GO:0031994	insulin-like growth factor I binding	4/2272	13/18639	0.307692307692308	2.52424160346696	0.0637891201418306	0.310594796577181
GO:0070123	transforming growth factor beta receptor activity, type III	4/2272	13/18639	0.307692307692308	2.52424160346696	0.0637891201418306	0.310594796577181
GO:0140666	annealing activity	4/2272	13/18639	0.307692307692308	2.52424160346696	0.0637891201418306	0.310594796577181
GO:0035591	signaling adaptor activity	22/2272	129/18639	0.170542635658915	1.3990951523092	0.06420921699231	0.310594796577181
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	8/2272	36/18639	0.222222222222222	1.82306338028169	0.0643885956367308	0.310594796577181
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	8/2272	36/18639	0.222222222222222	1.82306338028169	0.0643885956367308	0.310594796577181
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	8/2272	36/18639	0.222222222222222	1.82306338028169	0.0643885956367308	0.310594796577181
GO:0008106	alcohol dehydrogenase (NADP+) activity	7/2272	30/18639	0.233333333333333	1.91421654929577	0.064810514992122	0.311436787691151
GO:0030145	manganese ion binding	13/2272	68/18639	0.191176470588235	1.5683707021541	0.0651985053250968	0.312109955149418
GO:0019003	GDP binding	14/2272	75/18639	0.186666666666667	1.53137323943662	0.0675530502593802	0.322156402562726
GO:0008375	acetylglucosaminyltransferase activity	9/2272	43/18639	0.209302325581395	1.71707132328857	0.0713645519297443	0.337774326614843
GO:0048156	tau protein binding	9/2272	43/18639	0.209302325581395	1.71707132328857	0.0713645519297443	0.337774326614843
GO:0005520	insulin-like growth factor binding	5/2272	19/18639	0.263157894736842	2.15889084507042	0.0723218690659194	0.339750869977584
GO:0016918	retinal binding	5/2272	19/18639	0.263157894736842	2.15889084507042	0.0723218690659194	0.339750869977584
GO:0016887	ATP hydrolysis activity	61/2272	417/18639	0.146282973621103	1.20007409565306	0.0741888448679635	0.345926342651213
GO:0015271	outward rectifier potassium channel activity	6/2272	25/18639	0.24	1.96890845070423	0.0752463694182147	0.345926342651213
GO:0015662	P-type ion transporter activity	6/2272	25/18639	0.24	1.96890845070423	0.0752463694182147	0.345926342651213
GO:0047617	fatty acyl-CoA hydrolase activity	6/2272	25/18639	0.24	1.96890845070423	0.0752463694182147	0.345926342651213
GO:0140358	P-type transmembrane transporter activity	6/2272	25/18639	0.24	1.96890845070423	0.0752463694182147	0.345926342651213
GO:0017147	Wnt-protein binding	7/2272	31/18639	0.225806451612903	1.85246762835075	0.075285002292639	0.345926342651213
GO:0016874	ligase activity	27/2272	167/18639	0.161676646706587	1.32636048325883	0.0760877731145463	0.347515045456835
GO:1901682	sulfur compound transmembrane transporter activity	12/2272	63/18639	0.19047619047619	1.56262575452716	0.0761828058348583	0.347515045456835
GO:0004065	arylsulfatase activity	4/2272	14/18639	0.285714285714286	2.34393863179074	0.0809900806916612	0.364166112824291
GO:0005161	platelet-derived growth factor receptor binding	4/2272	14/18639	0.285714285714286	2.34393863179074	0.0809900806916612	0.364166112824291
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	4/2272	14/18639	0.285714285714286	2.34393863179074	0.0809900806916612	0.364166112824291
GO:0098821	BMP receptor activity	4/2272	14/18639	0.285714285714286	2.34393863179074	0.0809900806916612	0.364166112824291
GO:0043531	ADP binding	8/2272	38/18639	0.210526315789474	1.72711267605634	0.0839062070339067	0.375935639344087
GO:0030414	peptidase inhibitor activity	27/2272	169/18639	0.159763313609467	1.31066390949246	0.0852535882880712	0.377610846435046
GO:0005010	insulin-like growth factor receptor activity	10/2272	51/18639	0.196078431372549	1.60858533554267	0.0854798182954633	0.377610846435046
GO:0005021	vascular endothelial growth factor receptor activity	10/2272	51/18639	0.196078431372549	1.60858533554267	0.0854798182954633	0.377610846435046
GO:0005030	neurotrophin receptor activity	10/2272	51/18639	0.196078431372549	1.60858533554267	0.0854798182954633	0.377610846435046
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	7/2272	32/18639	0.21875	1.79457801496479	0.086692398948965	0.381628427541073
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	5/2272	20/18639	0.25	2.0509463028169	0.0871551879339853	0.382328855780096
GO:0005160	transforming growth factor beta receptor binding	6/2272	26/18639	0.230769230769231	1.89318120260022	0.0881837537571882	0.38283912407
GO:0016289	acyl-CoA hydrolase activity	6/2272	26/18639	0.230769230769231	1.89318120260022	0.0881837537571882	0.38283912407
GO:0070412	R-SMAD binding	6/2272	26/18639	0.230769230769231	1.89318120260022	0.0881837537571882	0.38283912407
GO:0140303	intramembrane lipid transporter activity	9/2272	45/18639	0.2	1.64075704225352	0.0902210504290103	0.390337809244412
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	8/2272	39/18639	0.205128205128205	1.68282773564464	0.0948323677419869	0.407487887328196
GO:0016776	phosphotransferase activity, phosphate group as acceptor	8/2272	39/18639	0.205128205128205	1.68282773564464	0.0948323677419869	0.407487887328196
GO:0004879	nuclear receptor activity	11/2272	59/18639	0.186440677966102	1.52951927667701	0.0982000421142752	0.420523309598206
GO:0005523	tropomyosin binding	4/2272	15/18639	0.266666666666667	2.18767605633803	0.100216367764218	0.421981294365052
GO:0015556	C4-dicarboxylate transmembrane transporter activity	4/2272	15/18639	0.266666666666667	2.18767605633803	0.100216367764218	0.421981294365052
GO:0120283	protein serine/threonine kinase binding	4/2272	15/18639	0.266666666666667	2.18767605633803	0.100216367764218	0.421981294365052
GO:0141050	histone H3K deacetylase activity	4/2272	15/18639	0.266666666666667	2.18767605633803	0.100216367764218	0.421981294365052
GO:0141051	histone H4K deacetylase activity	4/2272	15/18639	0.266666666666667	2.18767605633803	0.100216367764218	0.421981294365052
GO:0030291	protein serine/threonine kinase inhibitor activity	9/2272	46/18639	0.195652173913043	1.60508841090018	0.100649160665766	0.422390977593997
GO:0004683	calcium/calmodulin-dependent protein kinase activity	6/2272	27/18639	0.222222222222222	1.82306338028169	0.102251425268189	0.425588305781171
GO:0008320	protein transmembrane transporter activity	6/2272	27/18639	0.222222222222222	1.82306338028169	0.102251425268189	0.425588305781171
GO:0035401	histone H3Y41 kinase activity	19/2272	115/18639	0.165217391304348	1.35540799142682	0.103193023191647	0.425588305781171
GO:0140801	histone H2AXY142 kinase activity	19/2272	115/18639	0.165217391304348	1.35540799142682	0.103193023191647	0.425588305781171
GO:0008373	sialyltransferase activity	5/2272	21/18639	0.238095238095238	1.95328219315895	0.103439254621953	0.425588305781171
GO:0009975	cyclase activity	5/2272	21/18639	0.238095238095238	1.95328219315895	0.103439254621953	0.425588305781171
GO:0038064	collagen receptor activity	10/2272	53/18639	0.188679245283019	1.54788400212596	0.104789479351138	0.426007696547679
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	8/2272	40/18639	0.2	1.64075704225352	0.106527765409596	0.426007696547679
GO:0030331	nuclear estrogen receptor binding	8/2272	40/18639	0.2	1.64075704225352	0.106527765409596	0.426007696547679
GO:0004714	transmembrane receptor protein tyrosine kinase activity	11/2272	60/18639	0.183333333333333	1.50402728873239	0.107690694401852	0.426007696547679
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	11/2272	60/18639	0.183333333333333	1.50402728873239	0.107690694401852	0.426007696547679
GO:0098531	ligand-modulated transcription factor activity	11/2272	60/18639	0.183333333333333	1.50402728873239	0.107690694401852	0.426007696547679
GO:0031491	nucleosome binding	13/2272	74/18639	0.175675675675676	1.44120551008755	0.110906982502457	0.426007696547679
GO:0001784	phosphotyrosine residue binding	9/2272	47/18639	0.191489361702128	1.57093759364699	0.111736224908458	0.426007696547679
GO:0015020	glucuronosyltransferase activity	7/2272	34/18639	0.205882352941176	1.6890146023198	0.11225955761138	0.426007696547679
GO:0016831	carboxy-lyase activity	7/2272	34/18639	0.205882352941176	1.6890146023198	0.11225955761138	0.426007696547679
GO:0003680	minor groove of adenine-thymine-rich DNA binding	3/2272	10/18639	0.3	2.46113556338028	0.112677174702444	0.426007696547679
GO:0004090	carbonyl reductase (NADPH) activity	3/2272	10/18639	0.3	2.46113556338028	0.112677174702444	0.426007696547679
GO:0004862	cAMP-dependent protein kinase inhibitor activity	3/2272	10/18639	0.3	2.46113556338028	0.112677174702444	0.426007696547679
GO:0015203	polyamine transmembrane transporter activity	3/2272	10/18639	0.3	2.46113556338028	0.112677174702444	0.426007696547679
GO:0015658	branched-chain amino acid transmembrane transporter activity	3/2272	10/18639	0.3	2.46113556338028	0.112677174702444	0.426007696547679
GO:0016868	intramolecular phosphotransferase activity	3/2272	10/18639	0.3	2.46113556338028	0.112677174702444	0.426007696547679
GO:0030957	Tat protein binding	3/2272	10/18639	0.3	2.46113556338028	0.112677174702444	0.426007696547679
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	3/2272	10/18639	0.3	2.46113556338028	0.112677174702444	0.426007696547679
GO:0031434	mitogen-activated protein kinase kinase binding	3/2272	10/18639	0.3	2.46113556338028	0.112677174702444	0.426007696547679
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	3/2272	10/18639	0.3	2.46113556338028	0.112677174702444	0.426007696547679
GO:0035374	chondroitin sulfate binding	3/2272	10/18639	0.3	2.46113556338028	0.112677174702444	0.426007696547679
GO:0043295	glutathione binding	3/2272	10/18639	0.3	2.46113556338028	0.112677174702444	0.426007696547679
GO:0070739	protein-glutamic acid ligase activity	3/2272	10/18639	0.3	2.46113556338028	0.112677174702444	0.426007696547679
GO:0070740	tubulin-glutamic acid ligase activity	3/2272	10/18639	0.3	2.46113556338028	0.112677174702444	0.426007696547679
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	3/2272	10/18639	0.3	2.46113556338028	0.112677174702444	0.426007696547679
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	3/2272	10/18639	0.3	2.46113556338028	0.112677174702444	0.426007696547679
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	3/2272	10/18639	0.3	2.46113556338028	0.112677174702444	0.426007696547679
GO:0031072	heat shock protein binding	21/2272	131/18639	0.16030534351145	1.31511060638641	0.114630366201277	0.432094703734752
GO:0045499	chemorepellent activity	6/2272	28/18639	0.214285714285714	1.75795397384306	0.117414307182125	0.441267500723269
GO:0042169	SH2 domain binding	8/2272	41/18639	0.195121951219512	1.60073857780831	0.118978374249783	0.444026406318831
GO:0005548	phospholipid transporter activity	12/2272	68/18639	0.176470588235294	1.4477268019884	0.119184185717517	0.444026406318831
GO:0004866	endopeptidase inhibitor activity	25/2272	161/18639	0.15527950310559	1.27387969119062	0.120932743932561	0.444026406318831
GO:0050321	tau-protein kinase activity	5/2272	22/18639	0.227272727272727	1.86449663892446	0.121105511383954	0.444026406318831
GO:0005159	insulin-like growth factor receptor binding	4/2272	16/18639	0.25	2.0509463028169	0.121322544697123	0.444026406318831
GO:0019841	retinol binding	4/2272	16/18639	0.25	2.0509463028169	0.121322544697123	0.444026406318831
GO:0055102	lipase inhibitor activity	4/2272	16/18639	0.25	2.0509463028169	0.121322544697123	0.444026406318831
GO:0070411	I-SMAD binding	4/2272	16/18639	0.25	2.0509463028169	0.121322544697123	0.444026406318831
GO:0140328	floppase activity	4/2272	16/18639	0.25	2.0509463028169	0.121322544697123	0.444026406318831
GO:0015085	calcium ion transmembrane transporter activity	23/2272	147/18639	0.156462585034014	1.28358544121874	0.124776125494823	0.455342440573862
GO:0016229	steroid dehydrogenase activity	7/2272	35/18639	0.2	1.64075704225352	0.126375538917373	0.458614242106663
GO:0098632	cell-cell adhesion mediator activity	10/2272	55/18639	0.181818181818182	1.49159731113956	0.126401224790319	0.458614242106663
GO:0002039	p53 binding	12/2272	69/18639	0.173913043478261	1.4267452541335	0.129166477665413	0.465838198676231
GO:0001540	amyloid-beta binding	14/2272	83/18639	0.168674698795181	1.38377099949092	0.129357613911679	0.465838198676231
GO:0140034	methylation-dependent protein binding	13/2272	76/18639	0.171052631578947	1.40327904929577	0.129502279218968	0.465838198676231
GO:0031492	nucleosomal DNA binding	8/2272	42/18639	0.19047619047619	1.56262575452716	0.132164640383113	0.467271646320116
GO:0051879	Hsp90 protein binding	8/2272	42/18639	0.19047619047619	1.56262575452716	0.132164640383113	0.467271646320116
GO:0035250	UDP-galactosyltransferase activity	6/2272	29/18639	0.206896551724138	1.69733487129675	0.133625955124627	0.467271646320116
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	6/2272	29/18639	0.206896551724138	1.69733487129675	0.133625955124627	0.467271646320116
GO:0005004	GPI-linked ephrin receptor activity	9/2272	49/18639	0.183673469387755	1.50681769186548	0.135839096547389	0.467271646320116
GO:0005008	hepatocyte growth factor receptor activity	9/2272	49/18639	0.183673469387755	1.50681769186548	0.135839096547389	0.467271646320116
GO:0005009	insulin receptor activity	9/2272	49/18639	0.183673469387755	1.50681769186548	0.135839096547389	0.467271646320116
GO:0005011	macrophage colony-stimulating factor receptor activity	9/2272	49/18639	0.183673469387755	1.50681769186548	0.135839096547389	0.467271646320116
GO:0005018	platelet-derived growth factor alpha-receptor activity	9/2272	49/18639	0.183673469387755	1.50681769186548	0.135839096547389	0.467271646320116
GO:0005020	stem cell factor receptor activity	9/2272	49/18639	0.183673469387755	1.50681769186548	0.135839096547389	0.467271646320116
GO:0008288	boss receptor activity	9/2272	49/18639	0.183673469387755	1.50681769186548	0.135839096547389	0.467271646320116
GO:0016763	pentosyltransferase activity	9/2272	49/18639	0.183673469387755	1.50681769186548	0.135839096547389	0.467271646320116
GO:0036332	placental growth factor receptor activity	9/2272	49/18639	0.183673469387755	1.50681769186548	0.135839096547389	0.467271646320116
GO:0038062	protein tyrosine kinase collagen receptor activity	9/2272	49/18639	0.183673469387755	1.50681769186548	0.135839096547389	0.467271646320116
GO:0060175	brain-derived neurotrophic factor receptor activity	9/2272	49/18639	0.183673469387755	1.50681769186548	0.135839096547389	0.467271646320116
GO:0060590	ATPase regulator activity	9/2272	49/18639	0.183673469387755	1.50681769186548	0.135839096547389	0.467271646320116
GO:0016849	phosphorus-oxygen lyase activity	5/2272	23/18639	0.217391304347826	1.78343156766687	0.140068324814009	0.468761264808189
GO:0017134	fibroblast growth factor binding	5/2272	23/18639	0.217391304347826	1.78343156766687	0.140068324814009	0.468761264808189
GO:0004033	aldo-keto reductase (NADPH) activity	7/2272	36/18639	0.194444444444444	1.59518045774648	0.141337904536838	0.468761264808189
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	3/2272	11/18639	0.272727272727273	2.23739596670935	0.141484734413909	0.468761264808189
GO:0002162	dystroglycan binding	3/2272	11/18639	0.272727272727273	2.23739596670935	0.141484734413909	0.468761264808189
GO:0004016	adenylate cyclase activity	3/2272	11/18639	0.272727272727273	2.23739596670935	0.141484734413909	0.468761264808189
GO:0005114	type II transforming growth factor beta receptor binding	3/2272	11/18639	0.272727272727273	2.23739596670935	0.141484734413909	0.468761264808189
GO:0005225	volume-sensitive anion channel activity	3/2272	11/18639	0.272727272727273	2.23739596670935	0.141484734413909	0.468761264808189
GO:0008432	JUN kinase binding	3/2272	11/18639	0.272727272727273	2.23739596670935	0.141484734413909	0.468761264808189
GO:0043522	leucine zipper domain binding	3/2272	11/18639	0.272727272727273	2.23739596670935	0.141484734413909	0.468761264808189
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	3/2272	11/18639	0.272727272727273	2.23739596670935	0.141484734413909	0.468761264808189
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	3/2272	11/18639	0.272727272727273	2.23739596670935	0.141484734413909	0.468761264808189
GO:0180030	inositol phosphate kinase activity	3/2272	11/18639	0.272727272727273	2.23739596670935	0.141484734413909	0.468761264808189
GO:1900750	oligopeptide binding	3/2272	11/18639	0.272727272727273	2.23739596670935	0.141484734413909	0.468761264808189
GO:0015297	antiporter activity	21/2272	135/18639	0.155555555555556	1.27614436619718	0.143377300548262	0.472570214159711
GO:0008429	phosphatidylethanolamine binding	4/2272	17/18639	0.235294117647059	1.9303024026512	0.144135792086838	0.472570214159711
GO:0008484	sulfuric ester hydrolase activity	4/2272	17/18639	0.235294117647059	1.9303024026512	0.144135792086838	0.472570214159711
GO:0017110	nucleoside diphosphate phosphatase activity	4/2272	17/18639	0.235294117647059	1.9303024026512	0.144135792086838	0.472570214159711
GO:0019842	vitamin binding	23/2272	150/18639	0.153333333333333	1.25791373239437	0.145808681753421	0.476403654284547
GO:0005245	voltage-gated calcium channel activity	8/2272	43/18639	0.186046511627907	1.52628562070095	0.146061803458169	0.476403654284547
GO:0052689	carboxylic ester hydrolase activity	15/2272	92/18639	0.16304347826087	1.33757367575015	0.147221829962672	0.477973149480692
GO:0019887	protein kinase regulator activity	37/2272	255/18639	0.145098039215686	1.19035314830157	0.148503295600565	0.477973149480692
GO:0005006	epidermal growth factor receptor activity	9/2272	50/18639	0.18	1.47668133802817	0.14882086941734	0.477973149480692
GO:0005007	fibroblast growth factor receptor activity	9/2272	50/18639	0.18	1.47668133802817	0.14882086941734	0.477973149480692
GO:0005017	platelet-derived growth factor receptor activity	9/2272	50/18639	0.18	1.47668133802817	0.14882086941734	0.477973149480692
GO:0005019	platelet-derived growth factor beta-receptor activity	9/2272	50/18639	0.18	1.47668133802817	0.14882086941734	0.477973149480692
GO:0016769	transferase activity, transferring nitrogenous groups	6/2272	30/18639	0.2	1.64075704225352	0.150829815157753	0.481966338283278
GO:0098918	structural constituent of synapse	6/2272	30/18639	0.2	1.64075704225352	0.150829815157753	0.481966338283278
GO:0019207	kinase regulator activity	41/2272	287/18639	0.142857142857143	1.17196931589537	0.157784307814658	0.502912515287734
GO:0043177	organic acid binding	28/2272	189/18639	0.148148148148148	1.21537558685446	0.159053311626722	0.504317381670464
GO:0005315	phosphate transmembrane transporter activity	5/2272	24/18639	0.208333333333333	1.70912191901408	0.16022792110261	0.504317381670464
GO:0005540	hyaluronic acid binding	5/2272	24/18639	0.208333333333333	1.70912191901408	0.16022792110261	0.504317381670464
GO:0030215	semaphorin receptor binding	5/2272	24/18639	0.208333333333333	1.70912191901408	0.16022792110261	0.504317381670464
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	5/2272	24/18639	0.208333333333333	1.70912191901408	0.16022792110261	0.504317381670464
GO:0019205	nucleobase-containing compound kinase activity	8/2272	44/18639	0.181818181818182	1.49159731113956	0.160640273283965	0.504354374225715
GO:0005048	signal sequence binding	9/2272	51/18639	0.176470588235294	1.4477268019884	0.162393951800599	0.508592003276006
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	4/2272	18/18639	0.222222222222222	1.82306338028169	0.168463750618198	0.516805355778173
GO:0008409	5'-3' exonuclease activity	4/2272	18/18639	0.222222222222222	1.82306338028169	0.168463750618198	0.516805355778173
GO:0017128	phospholipid scramblase activity	4/2272	18/18639	0.222222222222222	1.82306338028169	0.168463750618198	0.516805355778173
GO:0070064	proline-rich region binding	4/2272	18/18639	0.222222222222222	1.82306338028169	0.168463750618198	0.516805355778173
GO:1901611	phosphatidylglycerol binding	4/2272	18/18639	0.222222222222222	1.82306338028169	0.168463750618198	0.516805355778173
GO:0003774	cytoskeletal motor activity	23/2272	153/18639	0.150326797385621	1.23324875724938	0.168745816897157	0.516805355778173
GO:0070273	phosphatidylinositol-4-phosphate binding	6/2272	31/18639	0.193548387096774	1.58782939572921	0.168960570245381	0.516805355778173
GO:0008081	phosphoric diester hydrolase activity	14/2272	87/18639	0.160919540229885	1.32014934434191	0.169324775325048	0.516805355778173
GO:0004032	aldose reductase (NADPH) activity	3/2272	12/18639	0.25	2.0509463028169	0.172405281514561	0.516805355778173
GO:0005078	MAP-kinase scaffold activity	3/2272	12/18639	0.25	2.0509463028169	0.172405281514561	0.516805355778173
GO:0005095	GTPase inhibitor activity	3/2272	12/18639	0.25	2.0509463028169	0.172405281514561	0.516805355778173
GO:0005165	neurotrophin receptor binding	3/2272	12/18639	0.25	2.0509463028169	0.172405281514561	0.516805355778173
GO:0008504	monoamine transmembrane transporter activity	3/2272	12/18639	0.25	2.0509463028169	0.172405281514561	0.516805355778173
GO:0008603	cAMP-dependent protein kinase regulator activity	3/2272	12/18639	0.25	2.0509463028169	0.172405281514561	0.516805355778173
GO:0010853	cyclase activator activity	3/2272	12/18639	0.25	2.0509463028169	0.172405281514561	0.516805355778173
GO:0015368	calcium:monoatomic cation antiporter activity	3/2272	12/18639	0.25	2.0509463028169	0.172405281514561	0.516805355778173
GO:0016423	tRNA (guanine) methyltransferase activity	3/2272	12/18639	0.25	2.0509463028169	0.172405281514561	0.516805355778173
GO:0034452	dynactin binding	3/2272	12/18639	0.25	2.0509463028169	0.172405281514561	0.516805355778173
GO:0005109	frizzled binding	7/2272	38/18639	0.184210526315789	1.5112235915493	0.173635794376511	0.519257636864674
GO:0004715	non-membrane spanning protein tyrosine kinase activity	8/2272	45/18639	0.177777777777778	1.45845070422535	0.17586605119855	0.524680944215578
GO:0004197	cysteine-type endopeptidase activity	14/2272	88/18639	0.159090909090909	1.30514764724712	0.18019792234913	0.536333768883107
GO:0003707	nuclear steroid receptor activity	5/2272	25/18639	0.2	1.64075704225352	0.181473309023709	0.53758799073141
GO:0008139	nuclear localization sequence binding	5/2272	25/18639	0.2	1.64075704225352	0.181473309023709	0.53758799073141
GO:0015101	organic cation transmembrane transporter activity	13/2272	81/18639	0.160493827160494	1.316656885759	0.182980325283795	0.540779881531216
GO:0035064	methylated histone binding	12/2272	74/18639	0.162162162162162	1.33034354777313	0.185580510744002	0.547180007088286
GO:0008378	galactosyltransferase activity	6/2272	32/18639	0.1875	1.53820972711268	0.187945532852246	0.549010268818975
GO:0022884	macromolecule transmembrane transporter activity	6/2272	32/18639	0.1875	1.53820972711268	0.187945532852246	0.549010268818975
GO:0071813	lipoprotein particle binding	6/2272	32/18639	0.1875	1.53820972711268	0.187945532852246	0.549010268818975
GO:0071814	protein-lipid complex binding	6/2272	32/18639	0.1875	1.53820972711268	0.187945532852246	0.549010268818975
GO:0005003	ephrin receptor activity	9/2272	53/18639	0.169811320754717	1.39309560191337	0.191207048581124	0.554135819489335
GO:0005005	transmembrane-ephrin receptor activity	9/2272	53/18639	0.169811320754717	1.39309560191337	0.191207048581124	0.554135819489335
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	8/2272	46/18639	0.173913043478261	1.4267452541335	0.191701186047557	0.554135819489335
GO:0005229	intracellularly calcium-gated chloride channel activity	4/2272	19/18639	0.210526315789474	1.72711267605634	0.194101585698806	0.554135819489335
GO:0008301	DNA binding, bending	4/2272	19/18639	0.210526315789474	1.72711267605634	0.194101585698806	0.554135819489335
GO:0022821	solute:potassium antiporter activity	4/2272	19/18639	0.210526315789474	1.72711267605634	0.194101585698806	0.554135819489335
GO:0022840	leak channel activity	4/2272	19/18639	0.210526315789474	1.72711267605634	0.194101585698806	0.554135819489335
GO:0022842	narrow pore channel activity	4/2272	19/18639	0.210526315789474	1.72711267605634	0.194101585698806	0.554135819489335
GO:0031420	alkali metal ion binding	4/2272	19/18639	0.210526315789474	1.72711267605634	0.194101585698806	0.554135819489335
GO:0141147	intracellularly calcium-gated channel activity	4/2272	19/18639	0.210526315789474	1.72711267605634	0.194101585698806	0.554135819489335
GO:0044183	protein folding chaperone	12/2272	75/18639	0.16	1.31260563380282	0.198072546479227	0.56419306791255
GO:0015291	secondary active transmembrane transporter activity	40/2272	287/18639	0.139372822299652	1.14338469843451	0.203653211738838	0.567214447422665
GO:0005112	Notch binding	5/2272	26/18639	0.192307692307692	1.57765100216685	0.20368510789669	0.567214447422665
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	5/2272	26/18639	0.192307692307692	1.57765100216685	0.20368510789669	0.567214447422665
GO:0008157	protein phosphatase 1 binding	5/2272	26/18639	0.192307692307692	1.57765100216685	0.20368510789669	0.567214447422665
GO:0050681	nuclear androgen receptor binding	5/2272	26/18639	0.192307692307692	1.57765100216685	0.20368510789669	0.567214447422665
GO:0050750	low-density lipoprotein particle receptor binding	5/2272	26/18639	0.192307692307692	1.57765100216685	0.20368510789669	0.567214447422665
GO:0017154	semaphorin receptor activity	3/2272	13/18639	0.230769230769231	1.89318120260022	0.20499012992638	0.567214447422665
GO:0019855	calcium channel inhibitor activity	3/2272	13/18639	0.230769230769231	1.89318120260022	0.20499012992638	0.567214447422665
GO:0030955	potassium ion binding	3/2272	13/18639	0.230769230769231	1.89318120260022	0.20499012992638	0.567214447422665
GO:0045159	myosin II binding	3/2272	13/18639	0.230769230769231	1.89318120260022	0.20499012992638	0.567214447422665
GO:0061459	L-arginine transmembrane transporter activity	3/2272	13/18639	0.230769230769231	1.89318120260022	0.20499012992638	0.567214447422665
GO:0070700	BMP receptor binding	3/2272	13/18639	0.230769230769231	1.89318120260022	0.20499012992638	0.567214447422665
GO:0071837	HMG box domain binding	3/2272	13/18639	0.230769230769231	1.89318120260022	0.20499012992638	0.567214447422665
GO:0140104	molecular carrier activity	35/2272	249/18639	0.140562248995984	1.15314249957577	0.206834730820971	0.571063434437725
GO:0042626	ATPase-coupled transmembrane transporter activity	15/2272	98/18639	0.153061224489796	1.2556814098879	0.210164485222868	0.578683715019681
GO:0017022	myosin binding	12/2272	76/18639	0.157894736842105	1.29533450704225	0.210929471590526	0.578683715019681
GO:0140658	ATP-dependent chromatin remodeler activity	23/2272	158/18639	0.145569620253165	1.19422189784275	0.210973649876119	0.578683715019681
GO:0000339	RNA cap binding	4/2272	20/18639	0.2	1.64075704225352	0.220838185140011	0.59921395493809
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	4/2272	20/18639	0.2	1.64075704225352	0.220838185140011	0.59921395493809
GO:0005326	neurotransmitter transmembrane transporter activity	4/2272	20/18639	0.2	1.64075704225352	0.220838185140011	0.59921395493809
GO:0016505	peptidase activator activity involved in apoptotic process	4/2272	20/18639	0.2	1.64075704225352	0.220838185140011	0.59921395493809
GO:0061608	nuclear import signal receptor activity	4/2272	20/18639	0.2	1.64075704225352	0.220838185140011	0.59921395493809
GO:0005385	zinc ion transmembrane transporter activity	5/2272	27/18639	0.185185185185185	1.51921948356808	0.226738217584986	0.610041337104729
GO:0023026	MHC class II protein complex binding	5/2272	27/18639	0.185185185185185	1.51921948356808	0.226738217584986	0.610041337104729
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	5/2272	27/18639	0.185185185185185	1.51921948356808	0.226738217584986	0.610041337104729
GO:0061650	ubiquitin-like protein conjugating enzyme activity	7/2272	41/18639	0.170731707317073	1.40064625558227	0.227251300319395	0.610041337104729
GO:0140828	metal cation:monoatomic cation antiporter activity	7/2272	41/18639	0.170731707317073	1.40064625558227	0.227251300319395	0.610041337104729
GO:0008331	high voltage-gated calcium channel activity	3/2272	14/18639	0.214285714285714	1.75795397384306	0.238808325172213	0.63040518831579
GO:0008559	ABC-type xenobiotic transporter activity	3/2272	14/18639	0.214285714285714	1.75795397384306	0.238808325172213	0.63040518831579
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	3/2272	14/18639	0.214285714285714	1.75795397384306	0.238808325172213	0.63040518831579
GO:0030983	mismatched DNA binding	3/2272	14/18639	0.214285714285714	1.75795397384306	0.238808325172213	0.63040518831579
GO:0032036	myosin heavy chain binding	3/2272	14/18639	0.214285714285714	1.75795397384306	0.238808325172213	0.63040518831579
GO:0042813	Wnt receptor activity	3/2272	14/18639	0.214285714285714	1.75795397384306	0.238808325172213	0.63040518831579
GO:1901612	cardiolipin binding	3/2272	14/18639	0.214285714285714	1.75795397384306	0.238808325172213	0.63040518831579
GO:0008237	metallopeptidase activity	26/2272	184/18639	0.141304347826087	1.15923051898347	0.238842950616864	0.63040518831579
GO:0008514	organic anion transmembrane transporter activity	37/2272	269/18639	0.137546468401487	1.12840168333421	0.239360309698372	0.63044901654864
GO:0050660	flavin adenine dinucleotide binding	13/2272	86/18639	0.151162790697674	1.24010706681952	0.245277303123006	0.639032207137716
GO:0004520	DNA endonuclease activity	7/2272	42/18639	0.166666666666667	1.36729753521127	0.246268632306651	0.639032207137716
GO:0019894	kinesin binding	7/2272	42/18639	0.166666666666667	1.36729753521127	0.246268632306651	0.639032207137716
GO:0009931	calcium-dependent protein serine/threonine kinase activity	4/2272	21/18639	0.19047619047619	1.56262575452716	0.248461462908965	0.639032207137716
GO:0010314	phosphatidylinositol-5-phosphate binding	4/2272	21/18639	0.19047619047619	1.56262575452716	0.248461462908965	0.639032207137716
GO:0015174	basic amino acid transmembrane transporter activity	4/2272	21/18639	0.19047619047619	1.56262575452716	0.248461462908965	0.639032207137716
GO:0019200	carbohydrate kinase activity	4/2272	21/18639	0.19047619047619	1.56262575452716	0.248461462908965	0.639032207137716
GO:0036122	BMP binding	4/2272	21/18639	0.19047619047619	1.56262575452716	0.248461462908965	0.639032207137716
GO:0051010	microtubule plus-end binding	4/2272	21/18639	0.19047619047619	1.56262575452716	0.248461462908965	0.639032207137716
GO:0070182	DNA polymerase binding	4/2272	21/18639	0.19047619047619	1.56262575452716	0.248461462908965	0.639032207137716
GO:0004536	DNA nuclease activity	10/2272	64/18639	0.15625	1.28184143926056	0.248891741317035	0.639032207137716
GO:0033218	amide binding	34/2272	247/18639	0.137651821862348	1.12926598049837	0.249037967536479	0.639032207137716
GO:0061631	ubiquitin conjugating enzyme activity	6/2272	35/18639	0.171428571428571	1.40636317907445	0.249217485071182	0.639032207137716
GO:0016866	intramolecular transferase activity	5/2272	28/18639	0.178571428571429	1.46496164486922	0.250504285063868	0.641026209137012
GO:0004386	helicase activity	22/2272	155/18639	0.141935483870968	1.16440822353476	0.254476367487243	0.649869668694601
GO:0004175	endopeptidase activity	54/2272	405/18639	0.133333333333333	1.09383802816901	0.259265544064232	0.660759757038195
GO:0031406	carboxylic acid binding	26/2272	187/18639	0.13903743315508	1.14063323793026	0.265906978992254	0.676316942527774
GO:0043539	protein serine/threonine kinase activator activity	11/2272	73/18639	0.150684931506849	1.23618681265676	0.272905077341781	0.685819721087614
GO:0004865	protein serine/threonine phosphatase inhibitor activity	3/2272	15/18639	0.2	1.64075704225352	0.273456314524211	0.685819721087614
GO:0008242	omega peptidase activity	3/2272	15/18639	0.2	1.64075704225352	0.273456314524211	0.685819721087614
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	3/2272	15/18639	0.2	1.64075704225352	0.273456314524211	0.685819721087614
GO:0016846	carbon-sulfur lyase activity	3/2272	15/18639	0.2	1.64075704225352	0.273456314524211	0.685819721087614
GO:0061578	K63-linked deubiquitinase activity	3/2272	15/18639	0.2	1.64075704225352	0.273456314524211	0.685819721087614
GO:0140776	protein-containing complex destabilizing activity	3/2272	15/18639	0.2	1.64075704225352	0.273456314524211	0.685819721087614
GO:0004407	histone deacetylase activity	4/2272	22/18639	0.181818181818182	1.49159731113956	0.276762785470079	0.688625191515474
GO:0033558	protein lysine deacetylase activity	4/2272	22/18639	0.181818181818182	1.49159731113956	0.276762785470079	0.688625191515474
GO:0034062	5'-3' RNA polymerase activity	4/2272	22/18639	0.181818181818182	1.49159731113956	0.276762785470079	0.688625191515474
GO:0097747	RNA polymerase activity	4/2272	22/18639	0.181818181818182	1.49159731113956	0.276762785470079	0.688625191515474
GO:0016790	thiolester hydrolase activity	7/2272	44/18639	0.159090909090909	1.30514764724712	0.285639540534166	0.709310022746577
GO:0043022	ribosome binding	16/2272	112/18639	0.142857142857143	1.17196931589537	0.287455663859548	0.712414725982619
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	9/2272	59/18639	0.152542372881356	1.25142486273574	0.288580624091405	0.713797653695636
GO:0000510	H3-H4 histone complex chaperone activity	21/2272	151/18639	0.139072847682119	1.14092377110344	0.292782145911319	0.715789871496971
GO:0140584	chromatin extrusion motor activity	21/2272	151/18639	0.139072847682119	1.14092377110344	0.292782145911319	0.715789871496971
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	21/2272	151/18639	0.139072847682119	1.14092377110344	0.292782145911319	0.715789871496971
GO:0140849	ATP-dependent H2AZ histone chaperone activity	21/2272	151/18639	0.139072847682119	1.14092377110344	0.292782145911319	0.715789871496971
GO:0019213	deacetylase activity	6/2272	37/18639	0.162162162162162	1.33034354777313	0.292797286593281	0.715789871496971
GO:0022829	wide pore channel activity	6/2272	37/18639	0.162162162162162	1.33034354777313	0.292797286593281	0.715789871496971
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	8/2272	52/18639	0.153846153846154	1.26212080173348	0.297008650711844	0.720746217847108
GO:0022839	monoatomic ion-gated channel activity	5/2272	30/18639	0.166666666666667	1.36729753521127	0.299658761529901	0.720746217847108
GO:0031624	ubiquitin conjugating enzyme binding	5/2272	30/18639	0.166666666666667	1.36729753521127	0.299658761529901	0.720746217847108
GO:0033612	receptor serine/threonine kinase binding	5/2272	30/18639	0.166666666666667	1.36729753521127	0.299658761529901	0.720746217847108
GO:0035925	mRNA 3'-UTR AU-rich region binding	5/2272	30/18639	0.166666666666667	1.36729753521127	0.299658761529901	0.720746217847108
GO:0051721	protein phosphatase 2A binding	5/2272	30/18639	0.166666666666667	1.36729753521127	0.299658761529901	0.720746217847108
GO:0070566	adenylyltransferase activity	5/2272	30/18639	0.166666666666667	1.36729753521127	0.299658761529901	0.720746217847108
GO:0051082	unfolded protein binding	17/2272	121/18639	0.140495867768595	1.15259792224421	0.303536517910702	0.720746217847108
GO:0015616	DNA translocase activity	21/2272	152/18639	0.138157894736842	1.13341769366197	0.303581105407716	0.720746217847108
GO:0140674	ATP-dependent histone chaperone activity	21/2272	152/18639	0.138157894736842	1.13341769366197	0.303581105407716	0.720746217847108
GO:0004602	glutathione peroxidase activity	4/2272	23/18639	0.173913043478261	1.4267452541335	0.305540566660831	0.720746217847108
GO:0005283	amino acid:sodium symporter activity	4/2272	23/18639	0.173913043478261	1.4267452541335	0.305540566660831	0.720746217847108
GO:0031681	G-protein beta-subunit binding	4/2272	23/18639	0.173913043478261	1.4267452541335	0.305540566660831	0.720746217847108
GO:0070577	lysine-acetylated histone binding	4/2272	23/18639	0.173913043478261	1.4267452541335	0.305540566660831	0.720746217847108
GO:0099186	structural constituent of postsynapse	4/2272	23/18639	0.173913043478261	1.4267452541335	0.305540566660831	0.720746217847108
GO:0140103	catalytic activity, acting on a glycoprotein	4/2272	23/18639	0.173913043478261	1.4267452541335	0.305540566660831	0.720746217847108
GO:0046915	transition metal ion transmembrane transporter activity	7/2272	45/18639	0.155555555555556	1.27614436619718	0.3058609727802	0.720746217847108
GO:0003689	DNA clamp loader activity	22/2272	160/18639	0.1375	1.1280204665493	0.305933731277115	0.720746217847108
GO:0005324	long-chain fatty acid transmembrane transporter activity	3/2272	16/18639	0.1875	1.53820972711268	0.308564107561232	0.720746217847108
GO:0015385	sodium:proton antiporter activity	3/2272	16/18639	0.1875	1.53820972711268	0.308564107561232	0.720746217847108
GO:0022841	potassium ion leak channel activity	3/2272	16/18639	0.1875	1.53820972711268	0.308564107561232	0.720746217847108
GO:0031435	mitogen-activated protein kinase kinase kinase binding	3/2272	16/18639	0.1875	1.53820972711268	0.308564107561232	0.720746217847108
GO:0043023	ribosomal large subunit binding	3/2272	16/18639	0.1875	1.53820972711268	0.308564107561232	0.720746217847108
GO:0097027	ubiquitin-protein transferase activator activity	3/2272	16/18639	0.1875	1.53820972711268	0.308564107561232	0.720746217847108
GO:0030165	PDZ domain binding	12/2272	83/18639	0.144578313253012	1.18608942813508	0.309384048398977	0.721323179507986
GO:0061775	cohesin loader activity	21/2272	153/18639	0.137254901960784	1.12600973487987	0.314502149749396	0.726900623308557
GO:0005501	retinoid binding	6/2272	38/18639	0.157894736842105	1.29533450704225	0.315140066383925	0.726900623308557
GO:0019840	isoprenoid binding	6/2272	38/18639	0.157894736842105	1.29533450704225	0.315140066383925	0.726900623308557
GO:0004864	protein phosphatase inhibitor activity	8/2272	53/18639	0.150943396226415	1.23830720170077	0.315817824423972	0.726900623308557
GO:0005544	calcium-dependent phospholipid binding	8/2272	53/18639	0.150943396226415	1.23830720170077	0.315817824423972	0.726900623308557
GO:0051018	protein kinase A binding	8/2272	53/18639	0.150943396226415	1.23830720170077	0.315817824423972	0.726900623308557
GO:0140296	general transcription initiation factor binding	8/2272	53/18639	0.150943396226415	1.23830720170077	0.315817824423972	0.726900623308557
GO:0070325	lipoprotein particle receptor binding	5/2272	31/18639	0.161290322580645	1.32319116310768	0.324793029084617	0.74337295774506
GO:0140097	catalytic activity, acting on DNA	44/2272	336/18639	0.130952380952381	1.07430520623742	0.328324875370041	0.74337295774506
GO:0005262	calcium channel activity	18/2272	131/18639	0.137404580152672	1.12723766261692	0.330704670811188	0.74337295774506
GO:0001091	RNA polymerase II general transcription initiation factor binding	4/2272	24/18639	0.166666666666667	1.36729753521127	0.334603095772475	0.74337295774506
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	4/2272	24/18639	0.166666666666667	1.36729753521127	0.334603095772475	0.74337295774506
GO:0030552	cAMP binding	4/2272	24/18639	0.166666666666667	1.36729753521127	0.334603095772475	0.74337295774506
GO:0140033	acetylation-dependent protein binding	4/2272	24/18639	0.166666666666667	1.36729753521127	0.334603095772475	0.74337295774506
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	8/2272	54/18639	0.148148148148148	1.21537558685446	0.33484941981187	0.74337295774506
GO:0004029	aldehyde dehydrogenase (NAD+) activity	3/2272	17/18639	0.176470588235294	1.4477268019884	0.343798746591458	0.74337295774506
GO:0004550	nucleoside diphosphate kinase activity	3/2272	17/18639	0.176470588235294	1.4477268019884	0.343798746591458	0.74337295774506
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	3/2272	17/18639	0.176470588235294	1.4477268019884	0.343798746591458	0.74337295774506
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	3/2272	17/18639	0.176470588235294	1.4477268019884	0.343798746591458	0.74337295774506
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	3/2272	17/18639	0.176470588235294	1.4477268019884	0.343798746591458	0.74337295774506
GO:0019198	transmembrane receptor protein phosphatase activity	3/2272	17/18639	0.176470588235294	1.4477268019884	0.343798746591458	0.74337295774506
GO:0030169	low-density lipoprotein particle binding	3/2272	17/18639	0.176470588235294	1.4477268019884	0.343798746591458	0.74337295774506
GO:0030548	acetylcholine receptor regulator activity	3/2272	17/18639	0.176470588235294	1.4477268019884	0.343798746591458	0.74337295774506
GO:0031489	myosin V binding	3/2272	17/18639	0.176470588235294	1.4477268019884	0.343798746591458	0.74337295774506
GO:0032183	SUMO binding	3/2272	17/18639	0.176470588235294	1.4477268019884	0.343798746591458	0.74337295774506
GO:0051787	misfolded protein binding	3/2272	17/18639	0.176470588235294	1.4477268019884	0.343798746591458	0.74337295774506
GO:1901567	fatty acid derivative binding	3/2272	17/18639	0.176470588235294	1.4477268019884	0.343798746591458	0.74337295774506
GO:0005504	fatty acid binding	7/2272	47/18639	0.148936170212766	1.22184035061432	0.347044404696393	0.74337295774506
GO:0140359	ABC-type transporter activity	7/2272	47/18639	0.148936170212766	1.22184035061432	0.347044404696393	0.74337295774506
GO:0000182	rDNA binding	2/2272	10/18639	0.2	1.64075704225352	0.349089522660544	0.74337295774506
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	2/2272	10/18639	0.2	1.64075704225352	0.349089522660544	0.74337295774506
GO:0004382	GDP phosphatase activity	2/2272	10/18639	0.2	1.64075704225352	0.349089522660544	0.74337295774506
GO:0004955	prostaglandin receptor activity	2/2272	10/18639	0.2	1.64075704225352	0.349089522660544	0.74337295774506
GO:0005337	nucleoside transmembrane transporter activity	2/2272	10/18639	0.2	1.64075704225352	0.349089522660544	0.74337295774506
GO:0005345	purine nucleobase transmembrane transporter activity	2/2272	10/18639	0.2	1.64075704225352	0.349089522660544	0.74337295774506
GO:0008140	cAMP response element binding protein binding	2/2272	10/18639	0.2	1.64075704225352	0.349089522660544	0.74337295774506
GO:0015279	store-operated calcium channel activity	2/2272	10/18639	0.2	1.64075704225352	0.349089522660544	0.74337295774506
GO:0015924	mannosyl-oligosaccharide mannosidase activity	2/2272	10/18639	0.2	1.64075704225352	0.349089522660544	0.74337295774506
GO:0016427	tRNA (cytidine) methyltransferase activity	2/2272	10/18639	0.2	1.64075704225352	0.349089522660544	0.74337295774506
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	2/2272	10/18639	0.2	1.64075704225352	0.349089522660544	0.74337295774506
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	2/2272	10/18639	0.2	1.64075704225352	0.349089522660544	0.74337295774506
GO:0031957	very long-chain fatty acid-CoA ligase activity	2/2272	10/18639	0.2	1.64075704225352	0.349089522660544	0.74337295774506
GO:0042975	peroxisome proliferator activated receptor binding	2/2272	10/18639	0.2	1.64075704225352	0.349089522660544	0.74337295774506
GO:0043208	glycosphingolipid binding	2/2272	10/18639	0.2	1.64075704225352	0.349089522660544	0.74337295774506
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	2/2272	10/18639	0.2	1.64075704225352	0.349089522660544	0.74337295774506
GO:0043422	protein kinase B binding	2/2272	10/18639	0.2	1.64075704225352	0.349089522660544	0.74337295774506
GO:0050815	phosphoserine residue binding	2/2272	10/18639	0.2	1.64075704225352	0.349089522660544	0.74337295774506
GO:0051864	histone H3K36 demethylase activity	2/2272	10/18639	0.2	1.64075704225352	0.349089522660544	0.74337295774506
GO:0070097	delta-catenin binding	2/2272	10/18639	0.2	1.64075704225352	0.349089522660544	0.74337295774506
GO:0141109	transporter activator activity	2/2272	10/18639	0.2	1.64075704225352	0.349089522660544	0.74337295774506
GO:1905394	retromer complex binding	2/2272	10/18639	0.2	1.64075704225352	0.349089522660544	0.74337295774506
GO:0051059	NF-kappaB binding	5/2272	32/18639	0.15625	1.28184143926056	0.350135158016537	0.74337295774506
GO:0140142	nucleocytoplasmic carrier activity	5/2272	32/18639	0.15625	1.28184143926056	0.350135158016537	0.74337295774506
GO:1990782	protein tyrosine kinase binding	16/2272	117/18639	0.136752136752137	1.12188515709642	0.351330878425177	0.744655851746292
GO:0140597	protein carrier chaperone	25/2272	188/18639	0.132978723404255	1.09092888447708	0.352396465986706	0.745659076768508
GO:0140313	molecular sequestering activity	8/2272	55/18639	0.145454545454545	1.19327784891165	0.354051810311642	0.747904746950263
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	62/2272	484/18639	0.128099173553719	1.0508981055756	0.356816486056301	0.752482338266137
GO:0061791	GTPase motor activity	6/2272	40/18639	0.15	1.23056778169014	0.3604929844998	0.756434445808746
GO:0140662	ATP-dependent protein folding chaperone	6/2272	40/18639	0.15	1.23056778169014	0.3604929844998	0.756434445808746
GO:1990606	membrane scission GTPase motor activity	6/2272	40/18639	0.15	1.23056778169014	0.3604929844998	0.756434445808746
GO:0004709	MAP kinase kinase kinase activity	4/2272	25/18639	0.16	1.31260563380282	0.363770674200811	0.758257084137121
GO:0008483	transaminase activity	4/2272	25/18639	0.16	1.31260563380282	0.363770674200811	0.758257084137121
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	4/2272	25/18639	0.16	1.31260563380282	0.363770674200811	0.758257084137121
GO:0017056	structural constituent of nuclear pore	4/2272	25/18639	0.16	1.31260563380282	0.363770674200811	0.758257084137121
GO:0019212	phosphatase inhibitor activity	8/2272	56/18639	0.142857142857143	1.17196931589537	0.373374060760723	0.774428241347199
GO:0030170	pyridoxal phosphate binding	8/2272	56/18639	0.142857142857143	1.17196931589537	0.373374060760723	0.774428241347199
GO:0170055	lipid transmembrane transporter activity	8/2272	56/18639	0.142857142857143	1.17196931589537	0.373374060760723	0.774428241347199
GO:0019956	chemokine binding	5/2272	33/18639	0.151515151515152	1.24299775928297	0.375568927903297	0.775596705601159
GO:0140416	transcription regulator inhibitor activity	5/2272	33/18639	0.151515151515152	1.24299775928297	0.375568927903297	0.775596705601159
GO:0004519	endonuclease activity	17/2272	127/18639	0.133858267716535	1.09814447709881	0.378853392749532	0.775596705601159
GO:0015172	acidic amino acid transmembrane transporter activity	3/2272	18/18639	0.166666666666667	1.36729753521127	0.37886574578611	0.775596705601159
GO:0031690	adrenergic receptor binding	3/2272	18/18639	0.166666666666667	1.36729753521127	0.37886574578611	0.775596705601159
GO:0034185	apolipoprotein binding	3/2272	18/18639	0.166666666666667	1.36729753521127	0.37886574578611	0.775596705601159
GO:0050811	GABA receptor binding	3/2272	18/18639	0.166666666666667	1.36729753521127	0.37886574578611	0.775596705601159
GO:0099602	neurotransmitter receptor regulator activity	3/2272	18/18639	0.166666666666667	1.36729753521127	0.37886574578611	0.775596705601159
GO:0015175	neutral L-amino acid transmembrane transporter activity	6/2272	41/18639	0.146341463414634	1.20055393335623	0.383334416073583	0.776107755998704
GO:0001222	transcription corepressor binding	7/2272	49/18639	0.142857142857143	1.17196931589537	0.388782961285467	0.776107755998704
GO:0032182	ubiquitin-like protein binding	16/2272	120/18639	0.133333333333333	1.09383802816901	0.390929421106697	0.776107755998704
GO:0004601	peroxidase activity	8/2272	57/18639	0.140350877192982	1.15140845070423	0.392766273617546	0.776107755998704
GO:0070279	vitamin B6 binding	8/2272	57/18639	0.140350877192982	1.15140845070423	0.392766273617546	0.776107755998704
GO:0030507	spectrin binding	4/2272	26/18639	0.153846153846154	1.26212080173348	0.39287714080156	0.776107755998704
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	2/2272	11/18639	0.181818181818182	1.49159731113956	0.395223920048685	0.776107755998704
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	2/2272	11/18639	0.181818181818182	1.49159731113956	0.395223920048685	0.776107755998704
GO:0004143	ATP-dependent diacylglycerol kinase activity	2/2272	11/18639	0.181818181818182	1.49159731113956	0.395223920048685	0.776107755998704
GO:0004523	RNA-DNA hybrid ribonuclease activity	2/2272	11/18639	0.181818181818182	1.49159731113956	0.395223920048685	0.776107755998704
GO:0004954	prostanoid receptor activity	2/2272	11/18639	0.181818181818182	1.49159731113956	0.395223920048685	0.776107755998704
GO:0005536	D-glucose binding	2/2272	11/18639	0.181818181818182	1.49159731113956	0.395223920048685	0.776107755998704
GO:0008046	axon guidance receptor activity	2/2272	11/18639	0.181818181818182	1.49159731113956	0.395223920048685	0.776107755998704
GO:0015205	nucleobase transmembrane transporter activity	2/2272	11/18639	0.181818181818182	1.49159731113956	0.395223920048685	0.776107755998704
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	2/2272	11/18639	0.181818181818182	1.49159731113956	0.395223920048685	0.776107755998704
GO:0032050	clathrin heavy chain binding	2/2272	11/18639	0.181818181818182	1.49159731113956	0.395223920048685	0.776107755998704
GO:0032404	mismatch repair complex binding	2/2272	11/18639	0.181818181818182	1.49159731113956	0.395223920048685	0.776107755998704
GO:0032794	GTPase activating protein binding	2/2272	11/18639	0.181818181818182	1.49159731113956	0.395223920048685	0.776107755998704
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	2/2272	11/18639	0.181818181818182	1.49159731113956	0.395223920048685	0.776107755998704
GO:0045294	alpha-catenin binding	2/2272	11/18639	0.181818181818182	1.49159731113956	0.395223920048685	0.776107755998704
GO:0047676	arachidonate-CoA ligase activity	2/2272	11/18639	0.181818181818182	1.49159731113956	0.395223920048685	0.776107755998704
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	2/2272	11/18639	0.181818181818182	1.49159731113956	0.395223920048685	0.776107755998704
GO:0050786	RAGE receptor binding	2/2272	11/18639	0.181818181818182	1.49159731113956	0.395223920048685	0.776107755998704
GO:0070697	activin receptor binding	2/2272	11/18639	0.181818181818182	1.49159731113956	0.395223920048685	0.776107755998704
GO:0140031	phosphorylation-dependent protein binding	2/2272	11/18639	0.181818181818182	1.49159731113956	0.395223920048685	0.776107755998704
GO:0140537	transcription regulator activator activity	2/2272	11/18639	0.181818181818182	1.49159731113956	0.395223920048685	0.776107755998704
GO:0038024	cargo receptor activity	9/2272	65/18639	0.138461538461538	1.13590872156013	0.395759475259069	0.776107755998704
GO:0030971	receptor tyrosine kinase binding	11/2272	81/18639	0.135802469135802	1.11409428794992	0.399824049182925	0.781485185654685
GO:0008175	tRNA methyltransferase activity	5/2272	34/18639	0.147058823529412	1.206439001657	0.400984455864119	0.781485185654685
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	5/2272	34/18639	0.147058823529412	1.206439001657	0.400984455864119	0.781485185654685
GO:0090482	vitamin transmembrane transporter activity	5/2272	34/18639	0.147058823529412	1.206439001657	0.400984455864119	0.781485185654685
GO:0001216	DNA-binding transcription activator activity	62/2272	491/18639	0.126272912423625	1.03591585152463	0.402707097961754	0.783629422463444
GO:0015245	fatty acid transmembrane transporter activity	3/2272	19/18639	0.157894736842105	1.29533450704225	0.41350902580248	0.799333881702907
GO:0030506	ankyrin binding	3/2272	19/18639	0.157894736842105	1.29533450704225	0.41350902580248	0.799333881702907
GO:0046624	sphingolipid transporter activity	3/2272	19/18639	0.157894736842105	1.29533450704225	0.41350902580248	0.799333881702907
GO:0070003	threonine-type peptidase activity	3/2272	19/18639	0.157894736842105	1.29533450704225	0.41350902580248	0.799333881702907
GO:0008094	ATP-dependent activity, acting on DNA	27/2272	210/18639	0.128571428571429	1.05477238430583	0.414315125431144	0.799333881702907
GO:0003684	damaged DNA binding	10/2272	74/18639	0.135135135135135	1.10861962314427	0.415221889303973	0.799333881702907
GO:0048029	monosaccharide binding	10/2272	74/18639	0.135135135135135	1.10861962314427	0.415221889303973	0.799333881702907
GO:0005319	lipid transporter activity	23/2272	178/18639	0.129213483146067	1.06003966213008	0.415969873162223	0.799551252383571
GO:0008013	beta-catenin binding	14/2272	106/18639	0.132075471698113	1.08351880148817	0.417448535046069	0.801170282961892
GO:0001671	ATPase activator activity	4/2272	27/18639	0.148148148148148	1.21537558685446	0.421770866578356	0.805780760276405
GO:0004364	glutathione transferase activity	4/2272	27/18639	0.148148148148148	1.21537558685446	0.421770866578356	0.805780760276405
GO:0016405	CoA-ligase activity	4/2272	27/18639	0.148148148148148	1.21537558685446	0.421770866578356	0.805780760276405
GO:0005343	organic acid:sodium symporter activity	5/2272	35/18639	0.142857142857143	1.17196931589537	0.426278950996276	0.81315939288532
GO:0008200	ion channel inhibitor activity	6/2272	43/18639	0.13953488372093	1.14471421552571	0.428950403081008	0.81396817059405
GO:0030295	protein kinase activator activity	18/2272	139/18639	0.129496402877698	1.06236067484041	0.429956225818084	0.81396817059405
GO:0070851	growth factor receptor binding	18/2272	139/18639	0.129496402877698	1.06236067484041	0.429956225818084	0.81396817059405
GO:0016597	amino acid binding	7/2272	51/18639	0.137254901960784	1.12600973487987	0.430582050528703	0.81396817059405
GO:0016830	carbon-carbon lyase activity	7/2272	51/18639	0.137254901960784	1.12600973487987	0.430582050528703	0.81396817059405
GO:0030544	Hsp70 protein binding	7/2272	51/18639	0.137254901960784	1.12600973487987	0.430582050528703	0.81396817059405
GO:0000340	RNA 7-methylguanosine cap binding	2/2272	12/18639	0.166666666666667	1.36729753521127	0.43978764775551	0.815572212805327
GO:0003995	acyl-CoA dehydrogenase activity	2/2272	12/18639	0.166666666666667	1.36729753521127	0.43978764775551	0.815572212805327
GO:0005247	voltage-gated chloride channel activity	2/2272	12/18639	0.166666666666667	1.36729753521127	0.43978764775551	0.815572212805327
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	2/2272	12/18639	0.166666666666667	1.36729753521127	0.43978764775551	0.815572212805327
GO:0016208	AMP binding	2/2272	12/18639	0.166666666666667	1.36729753521127	0.43978764775551	0.815572212805327
GO:0035251	UDP-glucosyltransferase activity	2/2272	12/18639	0.166666666666667	1.36729753521127	0.43978764775551	0.815572212805327
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	2/2272	12/18639	0.166666666666667	1.36729753521127	0.43978764775551	0.815572212805327
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	2/2272	12/18639	0.166666666666667	1.36729753521127	0.43978764775551	0.815572212805327
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	2/2272	12/18639	0.166666666666667	1.36729753521127	0.43978764775551	0.815572212805327
GO:1990247	N6-methyladenosine-containing RNA reader activity	2/2272	12/18639	0.166666666666667	1.36729753521127	0.43978764775551	0.815572212805327
GO:1990817	poly(A) RNA polymerase activity	2/2272	12/18639	0.166666666666667	1.36729753521127	0.43978764775551	0.815572212805327
GO:0015081	sodium ion transmembrane transporter activity	21/2272	164/18639	0.128048780487805	1.05048469168671	0.439851892370784	0.815572212805327
GO:0140713	histone chaperone activity	21/2272	164/18639	0.128048780487805	1.05048469168671	0.439851892370784	0.815572212805327
GO:0019209	kinase activator activity	19/2272	148/18639	0.128378378378378	1.05318864198706	0.441631065643352	0.817666928889677
GO:0005496	steroid binding	14/2272	108/18639	0.12962962962963	1.06345363849765	0.446127124154445	0.823705834574531
GO:0001972	retinoic acid binding	3/2272	20/18639	0.15	1.23056778169014	0.447509762389975	0.823705834574531
GO:0010851	cyclase regulator activity	3/2272	20/18639	0.15	1.23056778169014	0.447509762389975	0.823705834574531
GO:0015095	magnesium ion transmembrane transporter activity	3/2272	20/18639	0.15	1.23056778169014	0.447509762389975	0.823705834574531
GO:0140030	modification-dependent protein binding	22/2272	173/18639	0.127167630057803	1.04325592282016	0.45030363824885	0.823967026692618
GO:0019789	SUMO transferase activity	4/2272	28/18639	0.142857142857143	1.17196931589537	0.450315296830771	0.823967026692618
GO:0050698	proteoglycan sulfotransferase activity	4/2272	28/18639	0.142857142857143	1.17196931589537	0.450315296830771	0.823967026692618
GO:0044390	ubiquitin-like protein conjugating enzyme binding	5/2272	36/18639	0.138888888888889	1.13941461267606	0.451357265483086	0.823967026692618
GO:0055106	ubiquitin-protein transferase regulator activity	5/2272	36/18639	0.138888888888889	1.13941461267606	0.451357265483086	0.823967026692618
GO:0016248	channel inhibitor activity	6/2272	44/18639	0.136363636363636	1.11869798335467	0.451578434009457	0.823967026692618
GO:0046873	metal ion transmembrane transporter activity	56/2272	450/18639	0.124444444444444	1.02091549295775	0.45551248085461	0.829942421701814
GO:0005246	calcium channel regulator activity	7/2272	53/18639	0.132075471698113	1.08351880148817	0.471986138719546	0.844839965060034
GO:0141110	transporter inhibitor activity	6/2272	45/18639	0.133333333333333	1.09383802816901	0.473996504967804	0.844839965060034
GO:0023023	MHC protein complex binding	5/2272	37/18639	0.135135135135135	1.10861962314427	0.476132262184618	0.844839965060034
GO:0030551	cyclic nucleotide binding	5/2272	37/18639	0.135135135135135	1.10861962314427	0.476132262184618	0.844839965060034
GO:0015171	amino acid transmembrane transporter activity	13/2272	102/18639	0.127450980392157	1.04558046810273	0.476711076810314	0.844839965060034
GO:0005416	amino acid:monoatomic cation symporter activity	4/2272	29/18639	0.137931034482759	1.1315565808645	0.478389114382167	0.844839965060034
GO:0016417	S-acyltransferase activity	4/2272	29/18639	0.137931034482759	1.1315565808645	0.478389114382167	0.844839965060034
GO:0106222	lncRNA binding	4/2272	29/18639	0.137931034482759	1.1315565808645	0.478389114382167	0.844839965060034
GO:0042562	hormone binding	12/2272	94/18639	0.127659574468085	1.04729172909799	0.478836186592337	0.844839965060034
GO:0001846	opsonin binding	3/2272	21/18639	0.142857142857143	1.17196931589537	0.480684478970143	0.844839965060034
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	3/2272	21/18639	0.142857142857143	1.17196931589537	0.480684478970143	0.844839965060034
GO:0005123	death receptor binding	3/2272	21/18639	0.142857142857143	1.17196931589537	0.480684478970143	0.844839965060034
GO:0016209	antioxidant activity	11/2272	86/18639	0.127906976744186	1.0493213642319	0.481107205765998	0.844839965060034
GO:0002161	aminoacyl-tRNA editing activity	2/2272	13/18639	0.153846153846154	1.26212080173348	0.482478105542625	0.844839965060034
GO:0005035	death receptor activity	2/2272	13/18639	0.153846153846154	1.26212080173348	0.482478105542625	0.844839965060034
GO:0008035	high-density lipoprotein particle binding	2/2272	13/18639	0.153846153846154	1.26212080173348	0.482478105542625	0.844839965060034
GO:0008253	5'-nucleotidase activity	2/2272	13/18639	0.153846153846154	1.26212080173348	0.482478105542625	0.844839965060034
GO:0009982	pseudouridine synthase activity	2/2272	13/18639	0.153846153846154	1.26212080173348	0.482478105542625	0.844839965060034
GO:0015651	quaternary ammonium group transmembrane transporter activity	2/2272	13/18639	0.153846153846154	1.26212080173348	0.482478105542625	0.844839965060034
GO:0019104	DNA N-glycosylase activity	2/2272	13/18639	0.153846153846154	1.26212080173348	0.482478105542625	0.844839965060034
GO:0039706	co-receptor binding	2/2272	13/18639	0.153846153846154	1.26212080173348	0.482478105542625	0.844839965060034
GO:0046975	histone H3K36 methyltransferase activity	2/2272	13/18639	0.153846153846154	1.26212080173348	0.482478105542625	0.844839965060034
GO:0051011	microtubule minus-end binding	2/2272	13/18639	0.153846153846154	1.26212080173348	0.482478105542625	0.844839965060034
GO:0071714	icosanoid transmembrane transporter activity	2/2272	13/18639	0.153846153846154	1.26212080173348	0.482478105542625	0.844839965060034
GO:0089720	caspase binding	2/2272	13/18639	0.153846153846154	1.26212080173348	0.482478105542625	0.844839965060034
GO:0140333	glycerophospholipid flippase activity	2/2272	13/18639	0.153846153846154	1.26212080173348	0.482478105542625	0.844839965060034
GO:0140410	monoatomic cation:bicarbonate symporter activity	2/2272	13/18639	0.153846153846154	1.26212080173348	0.482478105542625	0.844839965060034
GO:0140852	histone ubiquitin ligase activity	2/2272	13/18639	0.153846153846154	1.26212080173348	0.482478105542625	0.844839965060034
GO:0042826	histone deacetylase binding	16/2272	127/18639	0.125984251968504	1.03354774315182	0.484296460463489	0.846846171838239
GO:0050661	NADP binding	7/2272	54/18639	0.12962962962963	1.06345363849765	0.4924107564292	0.859840696732818
GO:0016779	nucleotidyltransferase activity	17/2272	136/18639	0.125	1.02547315140845	0.495009717395903	0.862811090446161
GO:0043021	ribonucleoprotein complex binding	22/2272	177/18639	0.124293785310734	1.01967951778467	0.495482460994896	0.862811090446161
GO:0033293	monocarboxylic acid binding	10/2272	79/18639	0.126582278481013	1.03845382421109	0.500396964838799	0.870165440237635
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	33/2272	268/18639	0.123134328358209	1.01016758198444	0.503369733532087	0.874127578643997
GO:0031210	phosphatidylcholine binding	4/2272	30/18639	0.133333333333333	1.09383802816901	0.505886091744055	0.877287313368822
GO:0008374	O-acyltransferase activity	7/2272	55/18639	0.127272727272727	1.0441181177977	0.51258810273801	0.884546911160386
GO:0005243	gap junction channel activity	3/2272	22/18639	0.136363636363636	1.11869798335467	0.512882641101733	0.884546911160386
GO:0031683	G-protein beta/gamma-subunit complex binding	3/2272	22/18639	0.136363636363636	1.11869798335467	0.512882641101733	0.884546911160386
GO:0140517	protein-RNA adaptor activity	3/2272	22/18639	0.136363636363636	1.11869798335467	0.512882641101733	0.884546911160386
GO:0061749	forked DNA-dependent helicase activity	6/2272	47/18639	0.127659574468085	1.04729172909799	0.517962652912292	0.885174700438023
GO:1990518	single-stranded 3'-5' DNA helicase activity	6/2272	47/18639	0.127659574468085	1.04729172909799	0.517962652912292	0.885174700438023
GO:0001217	DNA-binding transcription repressor activity	34/2272	278/18639	0.122302158273381	1.00334063734928	0.519470482773506	0.885174700438023
GO:0005313	L-glutamate transmembrane transporter activity	2/2272	14/18639	0.142857142857143	1.17196931589537	0.52308973560436	0.885174700438023
GO:0008195	phosphatidate phosphatase activity	2/2272	14/18639	0.142857142857143	1.17196931589537	0.52308973560436	0.885174700438023
GO:0008474	palmitoyl-(protein) hydrolase activity	2/2272	14/18639	0.142857142857143	1.17196931589537	0.52308973560436	0.885174700438023
GO:0015386	potassium:proton antiporter activity	2/2272	14/18639	0.142857142857143	1.17196931589537	0.52308973560436	0.885174700438023
GO:0019992	diacylglycerol binding	2/2272	14/18639	0.142857142857143	1.17196931589537	0.52308973560436	0.885174700438023
GO:0031404	chloride ion binding	2/2272	14/18639	0.142857142857143	1.17196931589537	0.52308973560436	0.885174700438023
GO:0032454	histone H3K9 demethylase activity	2/2272	14/18639	0.142857142857143	1.17196931589537	0.52308973560436	0.885174700438023
GO:0042043	neurexin family protein binding	2/2272	14/18639	0.142857142857143	1.17196931589537	0.52308973560436	0.885174700438023
GO:0061665	SUMO ligase activity	2/2272	14/18639	0.142857142857143	1.17196931589537	0.52308973560436	0.885174700438023
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	2/2272	14/18639	0.142857142857143	1.17196931589537	0.52308973560436	0.885174700438023
GO:0098599	palmitoyl hydrolase activity	2/2272	14/18639	0.142857142857143	1.17196931589537	0.52308973560436	0.885174700438023
GO:0000217	DNA secondary structure binding	5/2272	39/18639	0.128205128205128	1.0517673347779	0.524464891253528	0.886310467232472
GO:0046943	carboxylic acid transmembrane transporter activity	23/2272	188/18639	0.122340425531915	1.00365457371891	0.526135318434817	0.887941509261976
GO:0005310	dicarboxylic acid transmembrane transporter activity	4/2272	31/18639	0.129032258064516	1.05855293048614	0.532714693619527	0.894250399022645
GO:0005452	solute:inorganic anion antiporter activity	4/2272	31/18639	0.129032258064516	1.05855293048614	0.532714693619527	0.894250399022645
GO:0016411	acylglycerol O-acyltransferase activity	4/2272	31/18639	0.129032258064516	1.05855293048614	0.532714693619527	0.894250399022645
GO:0016878	acid-thiol ligase activity	4/2272	31/18639	0.129032258064516	1.05855293048614	0.532714693619527	0.894250399022645
GO:0005342	organic acid transmembrane transporter activity	23/2272	189/18639	0.121693121693122	0.998344232059021	0.536951726658149	0.899295245080273
GO:0004521	RNA endonuclease activity	9/2272	73/18639	0.123287671232877	1.0114255739919	0.538928566355139	0.899295245080273
GO:0009378	four-way junction helicase activity	6/2272	48/18639	0.125	1.02547315140845	0.539403605398559	0.899295245080273
GO:0036121	double-stranded DNA helicase activity	6/2272	48/18639	0.125	1.02547315140845	0.539403605398559	0.899295245080273
GO:0043138	3'-5' DNA helicase activity	6/2272	48/18639	0.125	1.02547315140845	0.539403605398559	0.899295245080273
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	22/2272	181/18639	0.121546961325967	0.997145163800482	0.540005723018814	0.899295245080273
GO:0005212	structural constituent of eye lens	3/2272	23/18639	0.130434782608696	1.07005894060012	0.543983952267868	0.899968194356433
GO:0008171	O-methyltransferase activity	3/2272	23/18639	0.130434782608696	1.07005894060012	0.543983952267868	0.899968194356433
GO:0042171	lysophosphatidic acid acyltransferase activity	3/2272	23/18639	0.130434782608696	1.07005894060012	0.543983952267868	0.899968194356433
GO:0071617	lysophospholipid acyltransferase activity	3/2272	23/18639	0.130434782608696	1.07005894060012	0.543983952267868	0.899968194356433
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	3/2272	23/18639	0.130434782608696	1.07005894060012	0.543983952267868	0.899968194356433
GO:0004177	aminopeptidase activity	5/2272	40/18639	0.125	1.02547315140845	0.547889449361203	0.902837867856998
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	5/2272	40/18639	0.125	1.02547315140845	0.547889449361203	0.902837867856998
GO:0050997	quaternary ammonium group binding	5/2272	40/18639	0.125	1.02547315140845	0.547889449361203	0.902837867856998
GO:0042277	peptide binding	30/2272	249/18639	0.120481927710843	0.988407856779229	0.556697191095615	0.902837867856998
GO:0042910	xenobiotic transmembrane transporter activity	4/2272	32/18639	0.125	1.02547315140845	0.558797484419954	0.902837867856998
GO:0043425	bHLH transcription factor binding	4/2272	32/18639	0.125	1.02547315140845	0.558797484419954	0.902837867856998
GO:0000774	adenyl-nucleotide exchange factor activity	2/2272	15/18639	0.133333333333333	1.09383802816901	0.561494877308998	0.902837867856998
GO:0004467	long-chain fatty acid-CoA ligase activity	2/2272	15/18639	0.133333333333333	1.09383802816901	0.561494877308998	0.902837867856998
GO:0004559	alpha-mannosidase activity	2/2272	15/18639	0.133333333333333	1.09383802816901	0.561494877308998	0.902837867856998
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	2/2272	15/18639	0.133333333333333	1.09383802816901	0.561494877308998	0.902837867856998
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	2/2272	15/18639	0.133333333333333	1.09383802816901	0.561494877308998	0.902837867856998
GO:0004953	icosanoid receptor activity	2/2272	15/18639	0.133333333333333	1.09383802816901	0.561494877308998	0.902837867856998
GO:0008252	nucleotidase activity	2/2272	15/18639	0.133333333333333	1.09383802816901	0.561494877308998	0.902837867856998
GO:0015929	hexosaminidase activity	2/2272	15/18639	0.133333333333333	1.09383802816901	0.561494877308998	0.902837867856998
GO:0030553	cGMP binding	2/2272	15/18639	0.133333333333333	1.09383802816901	0.561494877308998	0.902837867856998
GO:0031386	protein tag activity	2/2272	15/18639	0.133333333333333	1.09383802816901	0.561494877308998	0.902837867856998
GO:0034483	heparan sulfate sulfotransferase activity	2/2272	15/18639	0.133333333333333	1.09383802816901	0.561494877308998	0.902837867856998
GO:0042809	nuclear vitamin D receptor binding	2/2272	15/18639	0.133333333333333	1.09383802816901	0.561494877308998	0.902837867856998
GO:0045504	dynein heavy chain binding	2/2272	15/18639	0.133333333333333	1.09383802816901	0.561494877308998	0.902837867856998
GO:0047372	monoacylglycerol lipase activity	2/2272	15/18639	0.133333333333333	1.09383802816901	0.561494877308998	0.902837867856998
GO:0048531	beta-1,3-galactosyltransferase activity	2/2272	15/18639	0.133333333333333	1.09383802816901	0.561494877308998	0.902837867856998
GO:0141047	molecular tag activity	2/2272	15/18639	0.133333333333333	1.09383802816901	0.561494877308998	0.902837867856998
GO:0016829	lyase activity	24/2272	200/18639	0.12	0.984454225352113	0.56545858246782	0.908051473631359
GO:0043130	ubiquitin binding	12/2272	100/18639	0.12	0.984454225352113	0.569032584129874	0.912290957731678
GO:0001727	lipid kinase activity	5/2272	41/18639	0.121951219512195	1.0004616111302	0.570744315095596	0.912290957731678
GO:0017080	sodium channel regulator activity	5/2272	41/18639	0.121951219512195	1.0004616111302	0.570744315095596	0.912290957731678
GO:0017116	single-stranded DNA helicase activity	7/2272	58/18639	0.120689655172414	0.990112008256435	0.571230979765176	0.912290957731678
GO:0004622	lysophospholipase activity	3/2272	24/18639	0.125	1.02547315140845	0.573895503195781	0.912290957731678
GO:0048027	mRNA 5'-UTR binding	3/2272	24/18639	0.125	1.02547315140845	0.573895503195781	0.912290957731678
GO:0050699	WW domain binding	3/2272	24/18639	0.125	1.02547315140845	0.573895503195781	0.912290957731678
GO:0140612	DNA damage sensor activity	3/2272	24/18639	0.125	1.02547315140845	0.573895503195781	0.912290957731678
GO:0043178	alcohol binding	11/2272	92/18639	0.119565217391304	0.980887362216779	0.575101280233585	0.913054869879046
GO:0004527	exonuclease activity	10/2272	84/18639	0.119047619047619	0.976641096579477	0.581866089367358	0.922444847371792
GO:0022843	voltage-gated monoatomic cation channel activity	17/2272	143/18639	0.118881118881119	0.975275164975869	0.582481059301489	0.922444847371792
GO:0030296	protein tyrosine kinase activator activity	4/2272	33/18639	0.121212121212121	0.994398207426377	0.584070388767079	0.922640676860417
GO:0140311	protein sequestering activity	4/2272	33/18639	0.121212121212121	0.994398207426377	0.584070388767079	0.922640676860417
GO:0035198	miRNA binding	5/2272	42/18639	0.119047619047619	0.976641096579477	0.592982909923639	0.926262577790585
GO:0000062	fatty-acyl-CoA binding	2/2272	16/18639	0.125	1.02547315140845	0.597627844415822	0.926262577790585
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	2/2272	16/18639	0.125	1.02547315140845	0.597627844415822	0.926262577790585
GO:0005521	lamin binding	2/2272	16/18639	0.125	1.02547315140845	0.597627844415822	0.926262577790585
GO:0008142	oxysterol binding	2/2272	16/18639	0.125	1.02547315140845	0.597627844415822	0.926262577790585
GO:0015923	mannosidase activity	2/2272	16/18639	0.125	1.02547315140845	0.597627844415822	0.926262577790585
GO:0017070	U6 snRNA binding	2/2272	16/18639	0.125	1.02547315140845	0.597627844415822	0.926262577790585
GO:0034450	ubiquitin-ubiquitin ligase activity	2/2272	16/18639	0.125	1.02547315140845	0.597627844415822	0.926262577790585
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	2/2272	16/18639	0.125	1.02547315140845	0.597627844415822	0.926262577790585
GO:0140327	flippase activity	2/2272	16/18639	0.125	1.02547315140845	0.597627844415822	0.926262577790585
GO:0032934	sterol binding	8/2272	68/18639	0.117647058823529	0.965151201325601	0.59823132086038	0.926262577790585
GO:1990841	promoter-specific chromatin binding	8/2272	68/18639	0.117647058823529	0.965151201325601	0.59823132086038	0.926262577790585
GO:0003743	translation initiation factor activity	6/2272	51/18639	0.117647058823529	0.965151201325601	0.601024695331786	0.926262577790585
GO:0000030	mannosyltransferase activity	3/2272	25/18639	0.12	0.984454225352113	0.602548888967823	0.926262577790585
GO:0015645	fatty acid ligase activity	3/2272	25/18639	0.12	0.984454225352113	0.602548888967823	0.926262577790585
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	3/2272	25/18639	0.12	0.984454225352113	0.602548888967823	0.926262577790585
GO:0017025	TBP-class protein binding	3/2272	25/18639	0.12	0.984454225352113	0.602548888967823	0.926262577790585
GO:0019706	protein-cysteine S-palmitoyltransferase activity	3/2272	25/18639	0.12	0.984454225352113	0.602548888967823	0.926262577790585
GO:0019707	protein-cysteine S-acyltransferase activity	3/2272	25/18639	0.12	0.984454225352113	0.602548888967823	0.926262577790585
GO:0042974	nuclear retinoic acid receptor binding	3/2272	25/18639	0.12	0.984454225352113	0.602548888967823	0.926262577790585
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	3/2272	25/18639	0.12	0.984454225352113	0.602548888967823	0.926262577790585
GO:0120515	fatty acid-CoA ligase activity	3/2272	25/18639	0.12	0.984454225352113	0.602548888967823	0.926262577790585
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	7/2272	60/18639	0.116666666666667	0.957108274647887	0.608409558917939	0.933104317573361
GO:0030332	cyclin binding	4/2272	34/18639	0.117647058823529	0.965151201325601	0.608481846487474	0.933104317573361
GO:0005253	monoatomic anion channel activity	12/2272	103/18639	0.116504854368932	0.955780801312731	0.611725971274186	0.936937953569587
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	5/2272	43/18639	0.116279069767442	0.953928512938094	0.614566134508196	0.940144305401967
GO:0003697	single-stranded DNA binding	14/2272	121/18639	0.115702479338843	0.949198288906996	0.624351003414603	0.940418299497786
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	7/2272	61/18639	0.114754098360656	0.941417975063496	0.626339920704722	0.940418299497786
GO:0019905	syntaxin binding	7/2272	61/18639	0.114754098360656	0.941417975063496	0.626339920704722	0.940418299497786
GO:0005261	monoatomic cation channel activity	40/2272	341/18639	0.117302052785924	0.962320845896493	0.628185422091542	0.940418299497786
GO:0004529	DNA exonuclease activity	3/2272	26/18639	0.115384615384615	0.946590601300108	0.629897377859074	0.940418299497786
GO:0005227	calcium-activated cation channel activity	3/2272	26/18639	0.115384615384615	0.946590601300108	0.629897377859074	0.940418299497786
GO:0034237	protein kinase A regulatory subunit binding	3/2272	26/18639	0.115384615384615	0.946590601300108	0.629897377859074	0.940418299497786
GO:0043548	phosphatidylinositol 3-kinase binding	3/2272	26/18639	0.115384615384615	0.946590601300108	0.629897377859074	0.940418299497786
GO:0051139	metal cation:proton antiporter activity	3/2272	26/18639	0.115384615384615	0.946590601300108	0.629897377859074	0.940418299497786
GO:0097602	cullin family protein binding	3/2272	26/18639	0.115384615384615	0.946590601300108	0.629897377859074	0.940418299497786
GO:0005092	GDP-dissociation inhibitor activity	2/2272	17/18639	0.117647058823529	0.965151201325601	0.631471724125737	0.940418299497786
GO:0009881	photoreceptor activity	2/2272	17/18639	0.117647058823529	0.965151201325601	0.631471724125737	0.940418299497786
GO:0015278	intracellularly gated calcium channel activity	2/2272	17/18639	0.117647058823529	0.965151201325601	0.631471724125737	0.940418299497786
GO:0032977	membrane insertase activity	2/2272	17/18639	0.117647058823529	0.965151201325601	0.631471724125737	0.940418299497786
GO:0036041	long-chain fatty acid binding	2/2272	17/18639	0.117647058823529	0.965151201325601	0.631471724125737	0.940418299497786
GO:0038191	neuropilin binding	2/2272	17/18639	0.117647058823529	0.965151201325601	0.631471724125737	0.940418299497786
GO:0045125	bioactive lipid receptor activity	2/2272	17/18639	0.117647058823529	0.965151201325601	0.631471724125737	0.940418299497786
GO:0046965	nuclear retinoid X receptor binding	2/2272	17/18639	0.117647058823529	0.965151201325601	0.631471724125737	0.940418299497786
GO:0048038	quinone binding	2/2272	17/18639	0.117647058823529	0.965151201325601	0.631471724125737	0.940418299497786
GO:0070403	NAD+ binding	2/2272	17/18639	0.117647058823529	0.965151201325601	0.631471724125737	0.940418299497786
GO:0070492	oligosaccharide binding	2/2272	17/18639	0.117647058823529	0.965151201325601	0.631471724125737	0.940418299497786
GO:1990226	histone methyltransferase binding	2/2272	17/18639	0.117647058823529	0.965151201325601	0.631471724125737	0.940418299497786
GO:0008028	monocarboxylic acid transmembrane transporter activity	8/2272	70/18639	0.114285714285714	0.937575452716298	0.631925243347996	0.940418299497786
GO:0001046	core promoter sequence-specific DNA binding	5/2272	44/18639	0.113636363636364	0.932248319462228	0.635461993546496	0.943451238060187
GO:0030547	signaling receptor inhibitor activity	5/2272	44/18639	0.113636363636364	0.932248319462228	0.635461993546496	0.943451238060187
GO:0008146	sulfotransferase activity	6/2272	53/18639	0.113207547169811	0.928730401275578	0.639511268795285	0.948344743714092
GO:0015103	inorganic anion transmembrane transporter activity	19/2272	165/18639	0.115151515151515	0.944678297055058	0.640443361960301	0.948609638480022
GO:0015179	L-amino acid transmembrane transporter activity	7/2272	62/18639	0.112903225806452	0.926233814175375	0.643801803774134	0.952463538133531
GO:0000149	SNARE binding	12/2272	106/18639	0.113207547169811	0.928730401275578	0.652290071233181	0.963587757803241
GO:0045505	dynein intermediate chain binding	4/2272	36/18639	0.111111111111111	0.911531690140845	0.654571226523035	0.963587757803241
GO:0051539	4 iron, 4 sulfur cluster binding	5/2272	45/18639	0.111111111111111	0.911531690140845	0.655645179618832	0.963587757803241
GO:0005044	scavenger receptor activity	3/2272	27/18639	0.111111111111111	0.911531690140845	0.655913191769164	0.963587757803241
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	3/2272	27/18639	0.111111111111111	0.911531690140845	0.655913191769164	0.963587757803241
GO:0035255	ionotropic glutamate receptor binding	3/2272	27/18639	0.111111111111111	0.911531690140845	0.655913191769164	0.963587757803241
GO:0017069	snRNA binding	6/2272	54/18639	0.111111111111111	0.911531690140845	0.657898832841046	0.963945457870095
GO:0003746	translation elongation factor activity	2/2272	18/18639	0.111111111111111	0.911531690140845	0.663047471418191	0.963945457870095
GO:0004706	JUN kinase kinase kinase activity	2/2272	18/18639	0.111111111111111	0.911531690140845	0.663047471418191	0.963945457870095
GO:0008308	voltage-gated monoatomic anion channel activity	2/2272	18/18639	0.111111111111111	0.911531690140845	0.663047471418191	0.963945457870095
GO:0015280	ligand-gated sodium channel activity	2/2272	18/18639	0.111111111111111	0.911531690140845	0.663047471418191	0.963945457870095
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	2/2272	18/18639	0.111111111111111	0.911531690140845	0.663047471418191	0.963945457870095
GO:0016854	racemase and epimerase activity	2/2272	18/18639	0.111111111111111	0.911531690140845	0.663047471418191	0.963945457870095
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	2/2272	18/18639	0.111111111111111	0.911531690140845	0.663047471418191	0.963945457870095
GO:0070628	proteasome binding	2/2272	18/18639	0.111111111111111	0.911531690140845	0.663047471418191	0.963945457870095
GO:0016247	channel regulator activity	19/2272	168/18639	0.113095238095238	0.927809041750503	0.671903479894714	0.975693749927849
GO:0099106	ion channel regulator activity	18/2272	160/18639	0.1125	0.922925836267606	0.678162233494582	0.983647755725436
GO:0030246	carbohydrate binding	32/2272	280/18639	0.114285714285714	0.937575452716298	0.679614200515781	0.983761697364719
GO:0046625	sphingolipid binding	3/2272	28/18639	0.107142857142857	0.878976986921529	0.680584939161771	0.983761697364719
GO:0046966	nuclear thyroid hormone receptor binding	3/2272	28/18639	0.107142857142857	0.878976986921529	0.680584939161771	0.983761697364719
GO:0008234	cysteine-type peptidase activity	21/2272	187/18639	0.112299465240642	0.921280692174437	0.689540008398328	0.988364868402287
GO:0141108	transporter regulator activity	19/2272	170/18639	0.111764705882353	0.916893641259321	0.692028141986989	0.988364868402287
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	2/2272	19/18639	0.105263157894737	0.863556338028169	0.692404935608274	0.988364868402287
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	2/2272	19/18639	0.105263157894737	0.863556338028169	0.692404935608274	0.988364868402287
GO:0042577	lipid phosphatase activity	2/2272	19/18639	0.105263157894737	0.863556338028169	0.692404935608274	0.988364868402287
GO:0046527	glucosyltransferase activity	2/2272	19/18639	0.105263157894737	0.863556338028169	0.692404935608274	0.988364868402287
GO:0050145	nucleoside monophosphate kinase activity	2/2272	19/18639	0.105263157894737	0.863556338028169	0.692404935608274	0.988364868402287
GO:0097001	ceramide binding	2/2272	19/18639	0.105263157894737	0.863556338028169	0.692404935608274	0.988364868402287
GO:0120227	acyl-CoA binding	2/2272	19/18639	0.105263157894737	0.863556338028169	0.692404935608274	0.988364868402287
GO:0140036	ubiquitin-modified protein reader activity	2/2272	19/18639	0.105263157894737	0.863556338028169	0.692404935608274	0.988364868402287
GO:1990380	K48-linked deubiquitinase activity	2/2272	19/18639	0.105263157894737	0.863556338028169	0.692404935608274	0.988364868402287
GO:0043495	protein-membrane adaptor activity	5/2272	47/18639	0.106382978723404	0.87274310758166	0.69380305371718	0.989239008640917
GO:0008135	translation factor activity, RNA binding	9/2272	83/18639	0.108433734939759	0.889567071101307	0.695985281899649	0.991227907139885
GO:0008083	growth factor activity	18/2272	162/18639	0.111111111111111	0.911531690140845	0.698570854593405	0.993786108398979
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	3/2272	29/18639	0.103448275862069	0.848667435648373	0.703915226636341	0.995608606430022
GO:0097472	cyclin-dependent protein kinase activity	3/2272	29/18639	0.103448275862069	0.848667435648373	0.703915226636341	0.995608606430022
GO:0099604	ligand-gated calcium channel activity	3/2272	29/18639	0.103448275862069	0.848667435648373	0.703915226636341	0.995608606430022
GO:0031490	chromatin DNA binding	14/2272	128/18639	0.109375	0.897289007482394	0.707644632214949	0.995608606430022
GO:0180051	translation factor activity	9/2272	84/18639	0.107142857142857	0.878976986921529	0.709679585003524	0.995608606430022
GO:0008238	exopeptidase activity	11/2272	102/18639	0.107843137254902	0.884721934548467	0.712586378480339	0.995608606430022
GO:0015293	symporter activity	16/2272	146/18639	0.10958904109589	0.899044954659464	0.712899378668419	0.995608606430022
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	4/2272	39/18639	0.102564102564103	0.841413867822319	0.716571055628645	0.995608606430022
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	2/2272	20/18639	0.1	0.820378521126761	0.719615510410308	0.995608606430022
GO:0016004	phospholipase activator activity	2/2272	20/18639	0.1	0.820378521126761	0.719615510410308	0.995608606430022
GO:0030742	GTP-dependent protein binding	2/2272	20/18639	0.1	0.820378521126761	0.719615510410308	0.995608606430022
GO:0042288	MHC class I protein binding	2/2272	20/18639	0.1	0.820378521126761	0.719615510410308	0.995608606430022
GO:0005244	voltage-gated monoatomic ion channel activity	19/2272	173/18639	0.109826589595376	0.9009937515265	0.720859881852629	0.995608606430022
GO:0008173	RNA methyltransferase activity	7/2272	67/18639	0.104477611940299	0.857111887744377	0.72356976305103	0.995608606430022
GO:0001965	G-protein alpha-subunit binding	3/2272	30/18639	0.1	0.820378521126761	0.725918463846595	0.995608606430022
GO:0048019	receptor antagonist activity	3/2272	30/18639	0.1	0.820378521126761	0.725918463846595	0.995608606430022
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	1/2272	10/18639	0.1	0.820378521126761	0.727529720346005	0.995608606430022
GO:0004445	inositol-polyphosphate 5-phosphatase activity	1/2272	10/18639	0.1	0.820378521126761	0.727529720346005	0.995608606430022
GO:0004935	adrenergic receptor activity	1/2272	10/18639	0.1	0.820378521126761	0.727529720346005	0.995608606430022
GO:0008190	eukaryotic initiation factor 4E binding	1/2272	10/18639	0.1	0.820378521126761	0.727529720346005	0.995608606430022
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/2272	10/18639	0.1	0.820378521126761	0.727529720346005	0.995608606430022
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	1/2272	10/18639	0.1	0.820378521126761	0.727529720346005	0.995608606430022
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	1/2272	10/18639	0.1	0.820378521126761	0.727529720346005	0.995608606430022
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	1/2272	10/18639	0.1	0.820378521126761	0.727529720346005	0.995608606430022
GO:0019911	structural constituent of myelin sheath	1/2272	10/18639	0.1	0.820378521126761	0.727529720346005	0.995608606430022
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/2272	10/18639	0.1	0.820378521126761	0.727529720346005	0.995608606430022
GO:0031996	thioesterase binding	1/2272	10/18639	0.1	0.820378521126761	0.727529720346005	0.995608606430022
GO:0032052	bile acid binding	1/2272	10/18639	0.1	0.820378521126761	0.727529720346005	0.995608606430022
GO:0045322	unmethylated CpG binding	1/2272	10/18639	0.1	0.820378521126761	0.727529720346005	0.995608606430022
GO:0050308	sugar-phosphatase activity	1/2272	10/18639	0.1	0.820378521126761	0.727529720346005	0.995608606430022
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/2272	10/18639	0.1	0.820378521126761	0.727529720346005	0.995608606430022
GO:0070513	death domain binding	1/2272	10/18639	0.1	0.820378521126761	0.727529720346005	0.995608606430022
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/2272	10/18639	0.1	0.820378521126761	0.727529720346005	0.995608606430022
GO:0140999	histone H3K4 trimethyltransferase activity	1/2272	10/18639	0.1	0.820378521126761	0.727529720346005	0.995608606430022
GO:1990763	arrestin family protein binding	1/2272	10/18639	0.1	0.820378521126761	0.727529720346005	0.995608606430022
GO:0035254	glutamate receptor binding	5/2272	49/18639	0.102040816326531	0.837120939925266	0.72895375504021	0.996474242774836
GO:0004518	nuclease activity	23/2272	209/18639	0.110047846889952	0.902808898847631	0.731300713948743	0.997552152313398
GO:0004532	RNA exonuclease activity	4/2272	40/18639	0.1	0.820378521126761	0.735313456325027	0.997552152313398
GO:0003724	RNA helicase activity	8/2272	77/18639	0.103896103896104	0.85234132065118	0.736458970077713	0.997552152313398
GO:0022832	voltage-gated channel activity	19/2272	175/18639	0.108571428571429	0.890696680080483	0.739141406615768	0.997552152313398
GO:0008509	monoatomic anion transmembrane transporter activity	16/2272	149/18639	0.10738255033557	0.880943378391152	0.742712819531294	0.997552152313398
GO:0015125	bile acid transmembrane transporter activity	2/2272	21/18639	0.0952380952380952	0.781312877263581	0.744766145298746	0.997552152313398
GO:0035613	RNA stem-loop binding	2/2272	21/18639	0.0952380952380952	0.781312877263581	0.744766145298746	0.997552152313398
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	2/2272	21/18639	0.0952380952380952	0.781312877263581	0.744766145298746	0.997552152313398
GO:0032813	tumor necrosis factor receptor superfamily binding	5/2272	50/18639	0.1	0.820378521126761	0.745396103436611	0.997552152313398
GO:0048020	CCR chemokine receptor binding	5/2272	50/18639	0.1	0.820378521126761	0.745396103436611	0.997552152313398
GO:0008327	methyl-CpG binding	3/2272	31/18639	0.0967741935483871	0.793914697864607	0.746618867799495	0.997552152313398
GO:0047499	calcium-independent phospholipase A2 activity	3/2272	31/18639	0.0967741935483871	0.793914697864607	0.746618867799495	0.997552152313398
GO:0072349	modified amino acid transmembrane transporter activity	3/2272	31/18639	0.0967741935483871	0.793914697864607	0.746618867799495	0.997552152313398
GO:0016877	ligase activity, forming carbon-sulfur bonds	4/2272	41/18639	0.0975609756097561	0.800369288904157	0.753104714836317	0.997552152313398
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	6/2272	60/18639	0.1	0.820378521126761	0.755421117451317	0.997552152313398
GO:0042393	histone binding	27/2272	247/18639	0.109311740890688	0.896770043336945	0.756232271419296	0.997552152313398
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	1/2272	11/18639	0.0909090909090909	0.745798655569782	0.760760300375737	0.997552152313398
GO:0001851	complement component C3b binding	1/2272	11/18639	0.0909090909090909	0.745798655569782	0.760760300375737	0.997552152313398
GO:0003953	NAD+ nucleosidase activity	1/2272	11/18639	0.0909090909090909	0.745798655569782	0.760760300375737	0.997552152313398
GO:0008172	S-methyltransferase activity	1/2272	11/18639	0.0909090909090909	0.745798655569782	0.760760300375737	0.997552152313398
GO:0008526	phosphatidylinositol transfer activity	1/2272	11/18639	0.0909090909090909	0.745798655569782	0.760760300375737	0.997552152313398
GO:0010854	adenylate cyclase regulator activity	1/2272	11/18639	0.0909090909090909	0.745798655569782	0.760760300375737	0.997552152313398
GO:0015173	aromatic amino acid transmembrane transporter activity	1/2272	11/18639	0.0909090909090909	0.745798655569782	0.760760300375737	0.997552152313398
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/2272	11/18639	0.0909090909090909	0.745798655569782	0.760760300375737	0.997552152313398
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/2272	11/18639	0.0909090909090909	0.745798655569782	0.760760300375737	0.997552152313398
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	1/2272	11/18639	0.0909090909090909	0.745798655569782	0.760760300375737	0.997552152313398
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/2272	11/18639	0.0909090909090909	0.745798655569782	0.760760300375737	0.997552152313398
GO:0019107	myristoyltransferase activity	1/2272	11/18639	0.0909090909090909	0.745798655569782	0.760760300375737	0.997552152313398
GO:0019203	carbohydrate phosphatase activity	1/2272	11/18639	0.0909090909090909	0.745798655569782	0.760760300375737	0.997552152313398
GO:0019206	nucleoside kinase activity	1/2272	11/18639	0.0909090909090909	0.745798655569782	0.760760300375737	0.997552152313398
GO:0031731	CCR6 chemokine receptor binding	1/2272	11/18639	0.0909090909090909	0.745798655569782	0.760760300375737	0.997552152313398
GO:0034056	estrogen response element binding	1/2272	11/18639	0.0909090909090909	0.745798655569782	0.760760300375737	0.997552152313398
GO:0034511	U3 snoRNA binding	1/2272	11/18639	0.0909090909090909	0.745798655569782	0.760760300375737	0.997552152313398
GO:0050998	nitric-oxide synthase binding	1/2272	11/18639	0.0909090909090909	0.745798655569782	0.760760300375737	0.997552152313398
GO:0070990	snRNP binding	1/2272	11/18639	0.0909090909090909	0.745798655569782	0.760760300375737	0.997552152313398
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/2272	11/18639	0.0909090909090909	0.745798655569782	0.760760300375737	0.997552152313398
GO:0046982	protein heterodimerization activity	41/2272	369/18639	0.111111111111111	0.911531690140845	0.761289371141797	0.997552152313398
GO:0008186	ATP-dependent activity, acting on RNA	8/2272	79/18639	0.10126582278481	0.830763059368872	0.762223888555836	0.997552152313398
GO:0015079	potassium ion transmembrane transporter activity	17/2272	160/18639	0.10625	0.871652178697183	0.76255667262148	0.997552152313398
GO:0016782	transferase activity, transferring sulphur-containing groups	7/2272	70/18639	0.1	0.820378521126761	0.765123735807378	0.997552152313398
GO:0030515	snoRNA binding	3/2272	32/18639	0.09375	0.769104863556338	0.766048666080137	0.997552152313398
GO:0047498	calcium-dependent phospholipase A2 activity	3/2272	32/18639	0.09375	0.769104863556338	0.766048666080137	0.997552152313398
GO:0120015	sterol transfer activity	3/2272	32/18639	0.09375	0.769104863556338	0.766048666080137	0.997552152313398
GO:0015377	chloride:monoatomic cation symporter activity	2/2272	22/18639	0.0909090909090909	0.745798655569782	0.767954495718447	0.997552152313398
GO:0033691	sialic acid binding	2/2272	22/18639	0.0909090909090909	0.745798655569782	0.767954495718447	0.997552152313398
GO:0070034	telomerase RNA binding	2/2272	22/18639	0.0909090909090909	0.745798655569782	0.767954495718447	0.997552152313398
GO:0140035	ubiquitin-like protein reader activity	2/2272	22/18639	0.0909090909090909	0.745798655569782	0.767954495718447	0.997552152313398
GO:0140784	metal ion sensor activity	2/2272	22/18639	0.0909090909090909	0.745798655569782	0.767954495718447	0.997552152313398
GO:0048487	beta-tubulin binding	4/2272	42/18639	0.0952380952380952	0.781312877263581	0.769959641669231	0.997552152313398
GO:0005216	monoatomic ion channel activity	50/2272	448/18639	0.111607142857143	0.91560102804326	0.770056397086386	0.997552152313398
GO:0140299	molecular sensor activity	7/2272	71/18639	0.0985915492957746	0.808823894068637	0.777915281484484	0.997552152313398
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	3/2272	33/18639	0.0909090909090909	0.745798655569782	0.784246493811443	0.997552152313398
GO:0004712	protein serine/threonine/tyrosine kinase activity	4/2272	43/18639	0.0930232558139535	0.763142810350475	0.785897437275491	0.997552152313398
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	2/2272	23/18639	0.0869565217391304	0.713372627066748	0.789285023666121	0.997552152313398
GO:0004022	alcohol dehydrogenase (NAD+) activity	2/2272	23/18639	0.0869565217391304	0.713372627066748	0.789285023666121	0.997552152313398
GO:0003720	telomerase activity	1/2272	12/18639	0.0833333333333333	0.683648767605634	0.789939632432121	0.997552152313398
GO:0004126	cytidine deaminase activity	1/2272	12/18639	0.0833333333333333	0.683648767605634	0.789939632432121	0.997552152313398
GO:0004300	enoyl-CoA hydratase activity	1/2272	12/18639	0.0833333333333333	0.683648767605634	0.789939632432121	0.997552152313398
GO:0004526	ribonuclease P activity	1/2272	12/18639	0.0833333333333333	0.683648767605634	0.789939632432121	0.997552152313398
GO:0004875	complement receptor activity	1/2272	12/18639	0.0833333333333333	0.683648767605634	0.789939632432121	0.997552152313398
GO:0005049	nuclear export signal receptor activity	1/2272	12/18639	0.0833333333333333	0.683648767605634	0.789939632432121	0.997552152313398
GO:0015132	prostaglandin transmembrane transporter activity	1/2272	12/18639	0.0833333333333333	0.683648767605634	0.789939632432121	0.997552152313398
GO:0016801	hydrolase activity, acting on ether bonds	1/2272	12/18639	0.0833333333333333	0.683648767605634	0.789939632432121	0.997552152313398
GO:0016803	ether hydrolase activity	1/2272	12/18639	0.0833333333333333	0.683648767605634	0.789939632432121	0.997552152313398
GO:0016840	carbon-nitrogen lyase activity	1/2272	12/18639	0.0833333333333333	0.683648767605634	0.789939632432121	0.997552152313398
GO:0035014	phosphatidylinositol 3-kinase regulator activity	1/2272	12/18639	0.0833333333333333	0.683648767605634	0.789939632432121	0.997552152313398
GO:0045295	gamma-catenin binding	1/2272	12/18639	0.0833333333333333	0.683648767605634	0.789939632432121	0.997552152313398
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	1/2272	12/18639	0.0833333333333333	0.683648767605634	0.789939632432121	0.997552152313398
GO:0070679	inositol 1,4,5 trisphosphate binding	1/2272	12/18639	0.0833333333333333	0.683648767605634	0.789939632432121	0.997552152313398
GO:0097371	MDM2/MDM4 family protein binding	1/2272	12/18639	0.0833333333333333	0.683648767605634	0.789939632432121	0.997552152313398
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	1/2272	12/18639	0.0833333333333333	0.683648767605634	0.789939632432121	0.997552152313398
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	1/2272	12/18639	0.0833333333333333	0.683648767605634	0.789939632432121	0.997552152313398
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	1/2272	12/18639	0.0833333333333333	0.683648767605634	0.789939632432121	0.997552152313398
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	1/2272	12/18639	0.0833333333333333	0.683648767605634	0.789939632432121	0.997552152313398
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	1/2272	12/18639	0.0833333333333333	0.683648767605634	0.789939632432121	0.997552152313398
GO:0004620	phospholipase activity	11/2272	109/18639	0.100917431192661	0.827904929577465	0.789959885509498	0.997552152313398
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	3/2272	34/18639	0.0882352941176471	0.723863400994201	0.801255975810537	1
GO:0015485	cholesterol binding	5/2272	54/18639	0.0925925925925926	0.759609741784038	0.803768133398192	1
GO:0005254	chloride channel activity	8/2272	83/18639	0.0963855421686747	0.790726285423384	0.808225338611443	1
GO:0004806	triacylglycerol lipase activity	2/2272	24/18639	0.0833333333333333	0.683648767605634	0.808865889163425	1
GO:0042625	ATPase-coupled ion transmembrane transporter activity	2/2272	24/18639	0.0833333333333333	0.683648767605634	0.808865889163425	1
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	2/2272	24/18639	0.0833333333333333	0.683648767605634	0.808865889163425	1
GO:0046961	proton-transporting ATPase activity, rotational mechanism	2/2272	24/18639	0.0833333333333333	0.683648767605634	0.808865889163425	1
GO:0060229	lipase activator activity	2/2272	24/18639	0.0833333333333333	0.683648767605634	0.808865889163425	1
GO:0070840	dynein complex binding	2/2272	24/18639	0.0833333333333333	0.683648767605634	0.808865889163425	1
GO:0003678	DNA helicase activity	7/2272	74/18639	0.0945945945945946	0.77603373620099	0.813174661226158	1
GO:0016298	lipase activity	13/2272	130/18639	0.1	0.820378521126761	0.814503310420449	1
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	1/2272	13/18639	0.0769230769230769	0.631060400866739	0.815561426339579	1
GO:0003964	RNA-directed DNA polymerase activity	1/2272	13/18639	0.0769230769230769	0.631060400866739	0.815561426339579	1
GO:0004465	lipoprotein lipase activity	1/2272	13/18639	0.0769230769230769	0.631060400866739	0.815561426339579	1
GO:0008417	fucosyltransferase activity	1/2272	13/18639	0.0769230769230769	0.631060400866739	0.815561426339579	1
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/2272	13/18639	0.0769230769230769	0.631060400866739	0.815561426339579	1
GO:0031432	titin binding	1/2272	13/18639	0.0769230769230769	0.631060400866739	0.815561426339579	1
GO:0035673	oligopeptide transmembrane transporter activity	1/2272	13/18639	0.0769230769230769	0.631060400866739	0.815561426339579	1
GO:0043560	insulin receptor substrate binding	1/2272	13/18639	0.0769230769230769	0.631060400866739	0.815561426339579	1
GO:0046974	histone H3K9 methyltransferase activity	1/2272	13/18639	0.0769230769230769	0.631060400866739	0.815561426339579	1
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	1/2272	13/18639	0.0769230769230769	0.631060400866739	0.815561426339579	1
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/2272	13/18639	0.0769230769230769	0.631060400866739	0.815561426339579	1
GO:0097157	pre-mRNA intronic binding	1/2272	13/18639	0.0769230769230769	0.631060400866739	0.815561426339579	1
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	1/2272	13/18639	0.0769230769230769	0.631060400866739	0.815561426339579	1
GO:1901338	catecholamine binding	1/2272	13/18639	0.0769230769230769	0.631060400866739	0.815561426339579	1
GO:0004623	phospholipase A2 activity	3/2272	35/18639	0.0857142857142857	0.703181589537223	0.817124483150406	1
GO:0043015	gamma-tubulin binding	3/2272	35/18639	0.0857142857142857	0.703181589537223	0.817124483150406	1
GO:0120013	lipid transfer activity	6/2272	65/18639	0.0923076923076923	0.757272481040087	0.819783346620211	1
GO:0005126	cytokine receptor binding	29/2272	275/18639	0.105454545454545	0.865126440460947	0.82378805146819	1
GO:0001848	complement binding	2/2272	25/18639	0.08	0.656302816901408	0.826806497876086	1
GO:0005251	delayed rectifier potassium channel activity	2/2272	25/18639	0.08	0.656302816901408	0.826806497876086	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	2/2272	25/18639	0.08	0.656302816901408	0.826806497876086	1
GO:0120020	cholesterol transfer activity	2/2272	25/18639	0.08	0.656302816901408	0.826806497876086	1
GO:0004190	aspartic-type endopeptidase activity	3/2272	36/18639	0.0833333333333333	0.683648767605634	0.831902051934713	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	3/2272	36/18639	0.0833333333333333	0.683648767605634	0.831902051934713	1
GO:0016409	palmitoyltransferase activity	3/2272	36/18639	0.0833333333333333	0.683648767605634	0.831902051934713	1
GO:0008174	mRNA methyltransferase activity	1/2272	14/18639	0.0714285714285714	0.585984657947686	0.838059248703827	1
GO:0008494	translation activator activity	1/2272	14/18639	0.0714285714285714	0.585984657947686	0.838059248703827	1
GO:0015926	glucosidase activity	1/2272	14/18639	0.0714285714285714	0.585984657947686	0.838059248703827	1
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/2272	14/18639	0.0714285714285714	0.585984657947686	0.838059248703827	1
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	1/2272	14/18639	0.0714285714285714	0.585984657947686	0.838059248703827	1
GO:0046030	inositol trisphosphate phosphatase activity	1/2272	14/18639	0.0714285714285714	0.585984657947686	0.838059248703827	1
GO:0070742	C2H2 zinc finger domain binding	1/2272	14/18639	0.0714285714285714	0.585984657947686	0.838059248703827	1
GO:0071933	Arp2/3 complex binding	1/2272	14/18639	0.0714285714285714	0.585984657947686	0.838059248703827	1
GO:1901474	azole transmembrane transporter activity	1/2272	14/18639	0.0714285714285714	0.585984657947686	0.838059248703827	1
GO:0099095	ligand-gated monoatomic anion channel activity	4/2272	47/18639	0.0851063829787234	0.698194486065328	0.840976802904036	1
GO:0004896	cytokine receptor activity	9/2272	96/18639	0.09375	0.769104863556338	0.842249701702643	1
GO:0008143	poly(A) binding	2/2272	26/18639	0.0769230769230769	0.631060400866739	0.843215591210837	1
GO:0030247	polysaccharide binding	2/2272	26/18639	0.0769230769230769	0.631060400866739	0.843215591210837	1
GO:0052742	phosphatidylinositol kinase activity	2/2272	26/18639	0.0769230769230769	0.631060400866739	0.843215591210837	1
GO:0070006	metalloaminopeptidase activity	2/2272	26/18639	0.0769230769230769	0.631060400866739	0.843215591210837	1
GO:0120014	phospholipid transfer activity	2/2272	26/18639	0.0769230769230769	0.631060400866739	0.843215591210837	1
GO:0070001	aspartic-type peptidase activity	3/2272	37/18639	0.0810810810810811	0.665171773886563	0.845640451349771	1
GO:0061980	regulatory RNA binding	5/2272	58/18639	0.0862068965517241	0.707222863040311	0.850997590441975	1
GO:0003777	microtubule motor activity	6/2272	68/18639	0.0882352941176471	0.723863400994201	0.851468908443294	1
GO:0005041	low-density lipoprotein particle receptor activity	1/2272	15/18639	0.0666666666666667	0.546919014084507	0.8578138466606	1
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/2272	15/18639	0.0666666666666667	0.546919014084507	0.8578138466606	1
GO:0008020	G protein-coupled photoreceptor activity	1/2272	15/18639	0.0666666666666667	0.546919014084507	0.8578138466606	1
GO:0010181	FMN binding	1/2272	15/18639	0.0666666666666667	0.546919014084507	0.8578138466606	1
GO:0015116	sulfate transmembrane transporter activity	1/2272	15/18639	0.0666666666666667	0.546919014084507	0.8578138466606	1
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/2272	15/18639	0.0666666666666667	0.546919014084507	0.8578138466606	1
GO:0033130	acetylcholine receptor binding	1/2272	15/18639	0.0666666666666667	0.546919014084507	0.8578138466606	1
GO:0050700	CARD domain binding	1/2272	15/18639	0.0666666666666667	0.546919014084507	0.8578138466606	1
GO:0050780	dopamine receptor binding	1/2272	15/18639	0.0666666666666667	0.546919014084507	0.8578138466606	1
GO:0140161	monocarboxylate:sodium symporter activity	1/2272	15/18639	0.0666666666666667	0.546919014084507	0.8578138466606	1
GO:0005104	fibroblast growth factor receptor binding	2/2272	27/18639	0.0740740740740741	0.60768779342723	0.858199783166171	1
GO:0008266	poly(U) RNA binding	2/2272	27/18639	0.0740740740740741	0.60768779342723	0.858199783166171	1
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	2/2272	27/18639	0.0740740740740741	0.60768779342723	0.858199783166171	1
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	3/2272	38/18639	0.0789473684210526	0.647667253521127	0.858392387812682	1
GO:0005249	voltage-gated potassium channel activity	9/2272	98/18639	0.0918367346938776	0.753408845932739	0.858849290883942	1
GO:0015459	potassium channel regulator activity	5/2272	59/18639	0.0847457627118644	0.695236034853187	0.861208482001604	1
GO:0070888	E-box binding	5/2272	59/18639	0.0847457627118644	0.695236034853187	0.861208482001604	1
GO:0015370	solute:sodium symporter activity	7/2272	79/18639	0.0886075949367089	0.726917676947762	0.862087415031138	1
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	23/2272	229/18639	0.100436681222707	0.823960960083646	0.865877257776289	1
GO:0000049	tRNA binding	7/2272	80/18639	0.0875	0.717831205985915	0.870494752321086	1
GO:0001098	basal transcription machinery binding	5/2272	60/18639	0.0833333333333333	0.683648767605634	0.870825515142539	1
GO:0001099	basal RNA polymerase II transcription machinery binding	5/2272	60/18639	0.0833333333333333	0.683648767605634	0.870825515142539	1
GO:0005242	inward rectifier potassium channel activity	2/2272	28/18639	0.0714285714285714	0.585984657947686	0.871862463474202	1
GO:0051537	2 iron, 2 sulfur cluster binding	2/2272	28/18639	0.0714285714285714	0.585984657947686	0.871862463474202	1
GO:0051959	dynein light intermediate chain binding	2/2272	28/18639	0.0714285714285714	0.585984657947686	0.871862463474202	1
GO:0141052	histone H3 demethylase activity	2/2272	28/18639	0.0714285714285714	0.585984657947686	0.871862463474202	1
GO:0004708	MAP kinase kinase activity	1/2272	16/18639	0.0625	0.512736575704225	0.875159580143585	1
GO:0008296	3'-5'-DNA exonuclease activity	1/2272	16/18639	0.0625	0.512736575704225	0.875159580143585	1
GO:0015378	sodium:chloride symporter activity	1/2272	16/18639	0.0625	0.512736575704225	0.875159580143585	1
GO:0015562	efflux transmembrane transporter activity	1/2272	16/18639	0.0625	0.512736575704225	0.875159580143585	1
GO:0016722	oxidoreductase activity, acting on metal ions	1/2272	16/18639	0.0625	0.512736575704225	0.875159580143585	1
GO:0022858	alanine transmembrane transporter activity	1/2272	16/18639	0.0625	0.512736575704225	0.875159580143585	1
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	1/2272	16/18639	0.0625	0.512736575704225	0.875159580143585	1
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/2272	16/18639	0.0625	0.512736575704225	0.875159580143585	1
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	1/2272	16/18639	0.0625	0.512736575704225	0.875159580143585	1
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	16/2272	167/18639	0.0958083832335329	0.785991397486717	0.878254146231733	1
GO:0016836	hydro-lyase activity	5/2272	61/18639	0.0819672131147541	0.67244141075964	0.879872194838217	1
GO:0005272	sodium channel activity	4/2272	51/18639	0.0784313725490196	0.643434134217067	0.883626255593763	1
GO:0004629	phospholipase C activity	2/2272	29/18639	0.0689655172413793	0.565778290432249	0.884302999536265	1
GO:0004540	RNA nuclease activity	11/2272	121/18639	0.0909090909090909	0.745798655569782	0.885492928465459	1
GO:0015108	chloride transmembrane transporter activity	11/2272	121/18639	0.0909090909090909	0.745798655569782	0.885492928465459	1
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	1/2272	17/18639	0.0588235294117647	0.4825756006628	0.890390071144701	1
GO:0004549	tRNA-specific ribonuclease activity	1/2272	17/18639	0.0588235294117647	0.4825756006628	0.890390071144701	1
GO:0004659	prenyltransferase activity	1/2272	17/18639	0.0588235294117647	0.4825756006628	0.890390071144701	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/2272	17/18639	0.0588235294117647	0.4825756006628	0.890390071144701	1
GO:0016018	cyclosporin A binding	1/2272	17/18639	0.0588235294117647	0.4825756006628	0.890390071144701	1
GO:0070402	NADPH binding	1/2272	17/18639	0.0588235294117647	0.4825756006628	0.890390071144701	1
GO:0001530	lipopolysaccharide binding	3/2272	41/18639	0.0731707317073171	0.600276966678117	0.89125717373386	1
GO:0042287	MHC protein binding	3/2272	41/18639	0.0731707317073171	0.600276966678117	0.89125717373386	1
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	2/2272	30/18639	0.0666666666666667	0.546919014084507	0.895616180656956	1
GO:0008187	poly-pyrimidine tract binding	2/2272	30/18639	0.0666666666666667	0.546919014084507	0.895616180656956	1
GO:0032452	histone demethylase activity	2/2272	30/18639	0.0666666666666667	0.546919014084507	0.895616180656956	1
GO:0042056	chemoattractant activity	3/2272	42/18639	0.0714285714285714	0.585984657947686	0.900587753123447	1
GO:0017046	peptide hormone binding	4/2272	53/18639	0.0754716981132075	0.619153600850385	0.900945253331382	1
GO:0034212	protein N-acetyltransferase activity	4/2272	53/18639	0.0754716981132075	0.619153600850385	0.900945253331382	1
GO:0000400	four-way junction DNA binding	1/2272	18/18639	0.0555555555555556	0.455765845070423	0.90376316524626	1
GO:0000900	mRNA regulatory element binding translation repressor activity	1/2272	18/18639	0.0555555555555556	0.455765845070423	0.90376316524626	1
GO:0004970	glutamate-gated receptor activity	1/2272	18/18639	0.0555555555555556	0.455765845070423	0.90376316524626	1
GO:0015373	monoatomic anion:sodium symporter activity	1/2272	18/18639	0.0555555555555556	0.455765845070423	0.90376316524626	1
GO:0017075	syntaxin-1 binding	1/2272	18/18639	0.0555555555555556	0.455765845070423	0.90376316524626	1
GO:0030228	lipoprotein particle receptor activity	1/2272	18/18639	0.0555555555555556	0.455765845070423	0.90376316524626	1
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	1/2272	18/18639	0.0555555555555556	0.455765845070423	0.90376316524626	1
GO:1990381	ubiquitin-specific protease binding	1/2272	18/18639	0.0555555555555556	0.455765845070423	0.90376316524626	1
GO:0005164	tumor necrosis factor receptor binding	2/2272	31/18639	0.0645161290322581	0.529276465243071	0.905891857405746	1
GO:0140457	protein demethylase activity	2/2272	31/18639	0.0645161290322581	0.529276465243071	0.905891857405746	1
GO:0005506	iron ion binding	14/2272	154/18639	0.0909090909090909	0.745798655569782	0.908315258355318	1
GO:0015294	solute:monoatomic cation symporter activity	10/2272	116/18639	0.0862068965517241	0.707222863040311	0.912231999687726	1
GO:0099094	ligand-gated monoatomic cation channel activity	12/2272	136/18639	0.0882352941176471	0.723863400994201	0.914320954265906	1
GO:0015106	bicarbonate transmembrane transporter activity	2/2272	32/18639	0.0625	0.512736575704225	0.915214736827454	1
GO:0031369	translation initiation factor binding	2/2272	32/18639	0.0625	0.512736575704225	0.915214736827454	1
GO:0070717	poly-purine tract binding	2/2272	32/18639	0.0625	0.512736575704225	0.915214736827454	1
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	1/2272	19/18639	0.0526315789473684	0.431778169014085	0.915505289115037	1
GO:0034987	immunoglobulin receptor binding	1/2272	19/18639	0.0526315789473684	0.431778169014085	0.915505289115037	1
GO:0042800	histone H3K4 methyltransferase activity	1/2272	19/18639	0.0526315789473684	0.431778169014085	0.915505289115037	1
GO:0042834	peptidoglycan binding	1/2272	19/18639	0.0526315789473684	0.431778169014085	0.915505289115037	1
GO:0003735	structural constituent of ribosome	16/2272	175/18639	0.0914285714285714	0.750060362173038	0.916653374055083	1
GO:0008236	serine-type peptidase activity	18/2272	194/18639	0.0927835051546392	0.761175947437201	0.91677408725867	1
GO:0043014	alpha-tubulin binding	3/2272	44/18639	0.0681818181818182	0.559348991677337	0.917110152067921	1
GO:0001664	G protein-coupled receptor binding	29/2272	297/18639	0.0976430976430976	0.801043000426803	0.919224892097702	1
GO:0004252	serine-type endopeptidase activity	16/2272	176/18639	0.0909090909090909	0.745798655569782	0.920657736243511	1
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	5/2272	67/18639	0.0746268656716418	0.612222776960269	0.923508107230286	1
GO:0005125	cytokine activity	22/2272	234/18639	0.094017094017094	0.771296045503792	0.925255026444266	1
GO:0001614	purinergic nucleotide receptor activity	1/2272	20/18639	0.05	0.41018926056338	0.925815277467918	1
GO:0016408	C-acyltransferase activity	1/2272	20/18639	0.05	0.41018926056338	0.925815277467918	1
GO:0016502	nucleotide receptor activity	1/2272	20/18639	0.05	0.41018926056338	0.925815277467918	1
GO:0030627	pre-mRNA 5'-splice site binding	1/2272	20/18639	0.05	0.41018926056338	0.925815277467918	1
GO:0043024	ribosomal small subunit binding	1/2272	20/18639	0.05	0.41018926056338	0.925815277467918	1
GO:0052745	inositol phosphate phosphatase activity	1/2272	20/18639	0.05	0.41018926056338	0.925815277467918	1
GO:0140664	ATP-dependent DNA damage sensor activity	1/2272	20/18639	0.05	0.41018926056338	0.925815277467918	1
GO:0140939	histone H4 methyltransferase activity	1/2272	20/18639	0.05	0.41018926056338	0.925815277467918	1
GO:0016835	carbon-oxygen lyase activity	6/2272	79/18639	0.0759493670886076	0.623072294526654	0.930948924343336	1
GO:0016798	hydrolase activity, acting on glycosyl bonds	11/2272	130/18639	0.0846153846153846	0.694166440953413	0.930995830550245	1
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	11/2272	130/18639	0.0846153846153846	0.694166440953413	0.930995830550245	1
GO:0017171	serine hydrolase activity	18/2272	198/18639	0.0909090909090909	0.745798655569782	0.93117814527468	1
GO:0052866	phosphatidylinositol phosphate phosphatase activity	2/2272	34/18639	0.0588235294117647	0.4825756006628	0.931314821210657	1
GO:0008080	N-acetyltransferase activity	5/2272	69/18639	0.072463768115942	0.59447718922229	0.934558682761774	1
GO:0008408	3'-5' exonuclease activity	4/2272	58/18639	0.0689655172413793	0.565778290432249	0.934652165428513	1
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	1/2272	21/18639	0.0476190476190476	0.390656438631791	0.934867734076376	1
GO:0005248	voltage-gated sodium channel activity	1/2272	21/18639	0.0476190476190476	0.390656438631791	0.934867734076376	1
GO:0061891	calcium ion sensor activity	1/2272	21/18639	0.0476190476190476	0.390656438631791	0.934867734076376	1
GO:1904047	S-adenosyl-L-methionine binding	1/2272	21/18639	0.0476190476190476	0.390656438631791	0.934867734076376	1
GO:0061733	protein-lysine-acetyltransferase activity	3/2272	47/18639	0.0638297872340425	0.523645864548996	0.937233234721266	1
GO:0000175	3'-5'-RNA exonuclease activity	2/2272	35/18639	0.0571428571428571	0.468787726358149	0.938235447759763	1
GO:0034061	DNA polymerase activity	2/2272	35/18639	0.0571428571428571	0.468787726358149	0.938235447759763	1
GO:0140566	histone reader activity	2/2272	35/18639	0.0571428571428571	0.468787726358149	0.938235447759763	1
GO:0020037	heme binding	12/2272	142/18639	0.0845070422535211	0.693277623487403	0.938838454132877	1
GO:0031593	polyubiquitin modification-dependent protein binding	4/2272	59/18639	0.0677966101694915	0.55618882788255	0.939993524223198	1
GO:0019787	ubiquitin-like protein transferase activity	48/2272	479/18639	0.100208768267223	0.82209121114999	0.941390115600139	1
GO:0008649	rRNA methyltransferase activity	1/2272	22/18639	0.0454545454545455	0.372899327784891	0.942815983521992	1
GO:0008970	phospholipase A1 activity	1/2272	22/18639	0.0454545454545455	0.372899327784891	0.942815983521992	1
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	1/2272	22/18639	0.0454545454545455	0.372899327784891	0.942815983521992	1
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	3/2272	48/18639	0.0625	0.512736575704225	0.942867176691119	1
GO:0140693	molecular condensate scaffold activity	3/2272	48/18639	0.0625	0.512736575704225	0.942867176691119	1
GO:0005484	SNAP receptor activity	2/2272	36/18639	0.0555555555555556	0.455765845070423	0.944490353396531	1
GO:0061630	ubiquitin protein ligase activity	34/2272	353/18639	0.0963172804532578	0.790166280971951	0.945001925435653	1
GO:0005267	potassium channel activity	10/2272	124/18639	0.0806451612903226	0.661595581553839	0.945982045508767	1
GO:0061659	ubiquitin-like protein ligase activity	36/2272	372/18639	0.0967741935483871	0.793914697864607	0.946173501896558	1
GO:0042379	chemokine receptor binding	5/2272	72/18639	0.0694444444444444	0.569707306338028	0.948462255674263	1
GO:0008168	methyltransferase activity	18/2272	204/18639	0.0882352941176471	0.723863400994201	0.948815619207136	1
GO:0003887	DNA-directed DNA polymerase activity	1/2272	23/18639	0.0434782608695652	0.356686313533374	0.949794663515441	1
GO:0016917	GABA receptor activity	1/2272	23/18639	0.0434782608695652	0.356686313533374	0.949794663515441	1
GO:0043274	phospholipase binding	1/2272	23/18639	0.0434782608695652	0.356686313533374	0.949794663515441	1
GO:0140102	catalytic activity, acting on a rRNA	1/2272	23/18639	0.0434782608695652	0.356686313533374	0.949794663515441	1
GO:0016410	N-acyltransferase activity	7/2272	94/18639	0.074468085106383	0.610920175307162	0.949845490057582	1
GO:0101005	deubiquitinase activity	9/2272	115/18639	0.0782608695652174	0.642035364360074	0.950117146363555	1
GO:0030280	structural constituent of skin epidermis	2/2272	37/18639	0.0540540540540541	0.443447849257708	0.950138919227774	1
GO:0004842	ubiquitin-protein transferase activity	44/2272	449/18639	0.0979955456570156	0.803934408231124	0.952870610590602	1
GO:0008276	protein methyltransferase activity	7/2272	95/18639	0.0736842105263158	0.604489436619718	0.953338239025529	1
GO:0016755	aminoacyltransferase activity	49/2272	496/18639	0.0987903225806452	0.810454587403453	0.955122485691363	1
GO:0042162	telomeric DNA binding	2/2272	38/18639	0.0526315789473684	0.431778169014085	0.955235948750835	1
GO:0042887	amide transmembrane transporter activity	2/2272	38/18639	0.0526315789473684	0.431778169014085	0.955235948750835	1
GO:0019783	ubiquitin-like protein peptidase activity	10/2272	127/18639	0.078740157480315	0.64596733946989	0.955336773492184	1
GO:0015149	hexose transmembrane transporter activity	1/2272	24/18639	0.0416666666666667	0.341824383802817	0.955922001530746	1
GO:0015295	solute:proton symporter activity	1/2272	24/18639	0.0416666666666667	0.341824383802817	0.955922001530746	1
GO:0019957	C-C chemokine binding	1/2272	24/18639	0.0416666666666667	0.341824383802817	0.955922001530746	1
GO:0055056	D-glucose transmembrane transporter activity	1/2272	24/18639	0.0416666666666667	0.341824383802817	0.955922001530746	1
GO:0016407	acetyltransferase activity	7/2272	96/18639	0.0729166666666667	0.59819267165493	0.956611082807142	1
GO:0140101	catalytic activity, acting on a tRNA	11/2272	139/18639	0.079136690647482	0.649220412402472	0.960020274792924	1
GO:0004843	cysteine-type deubiquitinase activity	8/2272	108/18639	0.0740740740740741	0.60768779342723	0.96058127588492	1
GO:0051536	iron-sulfur cluster binding	5/2272	76/18639	0.0657894736842105	0.539722711267606	0.962830079686015	1
GO:0032451	demethylase activity	2/2272	40/18639	0.05	0.41018926056338	0.963973134881533	1
GO:0071855	neuropeptide receptor binding	2/2272	40/18639	0.05	0.41018926056338	0.963973134881533	1
GO:0051540	metal cluster binding	5/2272	77/18639	0.0649350649350649	0.532713325406987	0.965794422913891	1
GO:0001637	G protein-coupled chemoattractant receptor activity	1/2272	26/18639	0.0384615384615385	0.315530200433369	0.966025263101911	1
GO:0004435	phosphatidylinositol phospholipase C activity	1/2272	26/18639	0.0384615384615385	0.315530200433369	0.966025263101911	1
GO:0004950	chemokine receptor activity	1/2272	26/18639	0.0384615384615385	0.315530200433369	0.966025263101911	1
GO:0008066	glutamate receptor activity	1/2272	26/18639	0.0384615384615385	0.315530200433369	0.966025263101911	1
GO:0008198	ferrous iron binding	1/2272	26/18639	0.0384615384615385	0.315530200433369	0.966025263101911	1
GO:0015145	monosaccharide transmembrane transporter activity	1/2272	26/18639	0.0384615384615385	0.315530200433369	0.966025263101911	1
GO:0046906	tetrapyrrole binding	12/2272	152/18639	0.0789473684210526	0.647667253521127	0.966354577398038	1
GO:0008235	metalloexopeptidase activity	4/2272	66/18639	0.0606060606060606	0.497199103713188	0.967531113885897	1
GO:0008227	G protein-coupled amine receptor activity	2/2272	41/18639	0.0487804878048781	0.400184644452078	0.967702158530132	1
GO:0003727	single-stranded RNA binding	6/2272	89/18639	0.0674157303370786	0.553064171546131	0.967785111527546	1
GO:0140098	catalytic activity, acting on RNA	36/2272	387/18639	0.0930232558139535	0.763142810350475	0.970245638762058	1
GO:0004402	histone acetyltransferase activity	2/2272	42/18639	0.0476190476190476	0.390656438631791	0.971057878800466	1
GO:0016741	transferase activity, transferring one-carbon groups	18/2272	215/18639	0.0837209302325581	0.686828529315427	0.971214111346952	1
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	6/2272	91/18639	0.0659340659340659	0.540908915028633	0.97252016892152	1
GO:0051119	sugar transmembrane transporter activity	1/2272	28/18639	0.0357142857142857	0.292992328973843	0.973813505592682	1
GO:0016279	protein-lysine N-methyltransferase activity	4/2272	69/18639	0.0579710144927536	0.475581751377832	0.975254179756945	1
GO:0004181	metallocarboxypeptidase activity	1/2272	29/18639	0.0344827586206897	0.282889145216124	0.977010309380411	1
GO:0016278	lysine N-methyltransferase activity	4/2272	70/18639	0.0571428571428571	0.468787726358149	0.977419346748395	1
GO:0022836	gated channel activity	28/2272	318/18639	0.0880503144654088	0.722345867658783	0.978121316646944	1
GO:0008009	chemokine activity	2/2272	45/18639	0.0444444444444444	0.364612676056338	0.979225386021783	1
GO:0042605	peptide antigen binding	2/2272	45/18639	0.0444444444444444	0.364612676056338	0.979225386021783	1
GO:0036002	pre-mRNA binding	3/2272	59/18639	0.0508474576271186	0.417141620911912	0.980450037750826	1
GO:0070063	RNA polymerase binding	3/2272	59/18639	0.0508474576271186	0.417141620911912	0.980450037750826	1
GO:0004180	carboxypeptidase activity	2/2272	46/18639	0.0434782608695652	0.356686313533374	0.981413394151934	1
GO:0140938	histone H3 methyltransferase activity	2/2272	47/18639	0.0425531914893617	0.349097243032664	0.983376956793297	1
GO:0005179	hormone activity	9/2272	132/18639	0.0681818181818182	0.559348991677337	0.984745253711605	1
GO:0038187	pattern recognition receptor activity	2/2272	48/18639	0.0416666666666667	0.341824383802817	0.985138251580348	1
GO:0015276	ligand-gated monoatomic ion channel activity	14/2272	186/18639	0.0752688172043011	0.61748920945025	0.985414057808997	1
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	8/2272	122/18639	0.0655737704918033	0.537953128607712	0.985930164231286	1
GO:0019239	deaminase activity	1/2272	33/18639	0.0303030303030303	0.248599551856594	0.986343993112409	1
GO:0022834	ligand-gated channel activity	14/2272	188/18639	0.074468085106383	0.610920175307162	0.987159339143466	1
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	1/2272	34/18639	0.0294117647058824	0.2412878003314	0.988011543776099	1
GO:0019825	oxygen binding	1/2272	34/18639	0.0294117647058824	0.2412878003314	0.988011543776099	1
GO:0019843	rRNA binding	3/2272	65/18639	0.0461538461538462	0.378636240520043	0.98937064545406	1
GO:0000993	RNA polymerase II complex binding	1/2272	36/18639	0.0277777777777778	0.227882922535211	0.990760837834497	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/2272	36/18639	0.0277777777777778	0.227882922535211	0.990760837834497	1
GO:0140767	enzyme-substrate adaptor activity	9/2272	139/18639	0.0647482014388489	0.531180337420205	0.990956647639073	1
GO:0042054	histone methyltransferase activity	3/2272	67/18639	0.0447761194029851	0.367333666176161	0.991352079291292	1
GO:0016251	RNA polymerase II general transcription initiation factor activity	2/2272	53/18639	0.0377358490566038	0.309576800425193	0.991551550929338	1
GO:0004497	monooxygenase activity	6/2272	106/18639	0.0566037735849057	0.464365200637789	0.992134654456354	1
GO:0140463	chromatin-protein adaptor activity	2/2272	54/18639	0.037037037037037	0.303843896713615	0.992460679692685	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	2/2272	56/18639	0.0357142857142857	0.292992328973843	0.994000863803899	1
GO:0015144	carbohydrate transmembrane transporter activity	1/2272	40/18639	0.025	0.20509463028169	0.99451303397457	1
GO:0004812	aminoacyl-tRNA ligase activity	1/2272	41/18639	0.024390243902439	0.200092322226039	0.995183305860681	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	1/2272	41/18639	0.024390243902439	0.200092322226039	0.995183305860681	1
GO:0043175	RNA polymerase core enzyme binding	1/2272	42/18639	0.0238095238095238	0.195328219315895	0.99577173091093	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/2272	46/18639	0.0217391304347826	0.178343156766687	0.997489360770544	1
GO:0140375	immune receptor activity	9/2272	156/18639	0.0576923076923077	0.473295300650054	0.997635739026469	1
GO:0008188	neuropeptide receptor activity	1/2272	48/18639	0.0208333333333333	0.170912191901408	0.998065469194992	1
GO:0008528	G protein-coupled peptide receptor activity	6/2272	122/18639	0.0491803278688525	0.403464846455784	0.998117053328817	1
GO:0140223	general transcription initiation factor activity	2/2272	68/18639	0.0294117647058824	0.2412878003314	0.998506988461904	1
GO:0008170	N-methyltransferase activity	4/2272	98/18639	0.0408163265306122	0.334848375970106	0.998524787687634	1
GO:0098960	postsynaptic neurotransmitter receptor activity	2/2272	69/18639	0.0289855072463768	0.237790875688916	0.998672140733867	1
GO:0001653	peptide receptor activity	6/2272	128/18639	0.046875	0.384552431778169	0.998921188868228	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	1/2272	53/18639	0.0188679245283019	0.154788400212596	0.998991915172215	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	2/2272	73/18639	0.0273972602739726	0.224761238664866	0.999170634409894	1
GO:0030594	neurotransmitter receptor activity	3/2272	97/18639	0.0309278350515464	0.2537253158124	0.999660183880437	1
GO:0022824	transmitter-gated monoatomic ion channel activity	1/2272	63/18639	0.0158730158730159	0.130218812877264	0.999726412760802	1
GO:0022835	transmitter-gated channel activity	1/2272	63/18639	0.0158730158730159	0.130218812877264	0.999726412760802	1
GO:0003730	mRNA 3'-UTR binding	11/2272	262/18639	0.0419847328244275	0.34443373024406	0.999998151034939	1
GO:0003823	antigen binding	3/2272	174/18639	0.0172413793103448	0.141444572608062	0.999999956819033	1
GO:0045182	translation regulator activity	6/2272	356/18639	0.0168539325842697	0.138266042886533	0.999999999999985	1
GO:0030371	translation repressor activity	4/2272	329/18639	0.0121580547112462	0.099742069437904	0.999999999999997	1
GO:0004984	olfactory receptor activity	1/2272	419/18639	0.00238663484486874	0.0195794396450301	1	1