ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	38/665	175/18639	0.217142857142857	6.08620408163265	1.5173096570886e-19	1.47482498669012e-16
GO:0045296	cadherin binding	36/665	334/18639	0.107784431137725	3.02104362703165	3.74129732818962e-09	1.81827050150016e-06
GO:0017154	semaphorin receptor activity	6/665	13/18639	0.461538461538462	12.9362637362637	2.79271856314082e-06	0.000904840814457627
GO:0003712	transcription coregulator activity	37/665	495/18639	0.0747474747474747	2.09506493506494	1.97166197110673e-05	0.00479113858978935
GO:0004714	transmembrane receptor protein tyrosine kinase activity	10/665	60/18639	0.166666666666667	4.67142857142857	4.69672685527962e-05	0.00913043700666358
GO:0019199	transmembrane receptor protein kinase activity	11/665	78/18639	0.141025641025641	3.95274725274725	9.71119310309117e-05	0.0157321328270077
GO:0090482	vitamin transmembrane transporter activity	7/665	34/18639	0.205882352941176	5.77058823529412	0.000165410280829859	0.0229683989952319
GO:0035255	ionotropic glutamate receptor binding	6/665	27/18639	0.222222222222222	6.22857142857143	0.000314244872642412	0.038180752026053
GO:0005021	vascular endothelial growth factor receptor activity	8/665	51/18639	0.156862745098039	4.39663865546218	0.000412715145729402	0.0445732357387754
GO:0046332	SMAD binding	10/665	79/18639	0.126582278481013	3.54792043399638	0.000488985816066215	0.0475294213216361
GO:0003779	actin binding	30/665	443/18639	0.0677200902934537	1.89809738793937	0.000633233378531682	0.0559548039938905
GO:0098632	cell-cell adhesion mediator activity	8/665	55/18639	0.145454545454545	4.07688311688312	0.00069640308977403	0.0564086502716964
GO:0140789	histone phosphatase activity	13/665	136/18639	0.0955882352941176	2.67920168067227	0.00117025946279045	0.0874993998332551
GO:0098631	cell adhesion mediator activity	9/665	76/18639	0.118421052631579	3.31917293233083	0.00149827034267414	0.10371215665123
GO:0055105	ubiquitin-protein transferase inhibitor activity	4/665	15/18639	0.266666666666667	7.47428571428571	0.00160049624461775	0.10371215665123
GO:0005006	epidermal growth factor receptor activity	7/665	50/18639	0.14	3.924	0.00187544400978415	0.109495073017335
GO:0005178	integrin binding	14/665	161/18639	0.0869565217391304	2.43726708074534	0.0019150372852826	0.109495073017335
GO:0005010	insulin-like growth factor receptor activity	7/665	51/18639	0.137254901960784	3.84705882352941	0.00210815087452013	0.113840147224087
GO:0016500	protein-hormone receptor activity	8/665	67/18639	0.119402985074627	3.34669509594883	0.00256746365486034	0.122527693135163
GO:0097718	disordered domain specific binding	5/665	28/18639	0.178571428571429	5.00510204081633	0.00282984358315448	0.122527693135163
GO:0030695	GTPase regulator activity	30/665	489/18639	0.0613496932515337	1.71954425942156	0.00290757356489864	0.122527693135163
GO:0060589	nucleoside-triphosphatase regulator activity	30/665	490/18639	0.0612244897959184	1.71603498542274	0.00299563867904108	0.122527693135163
GO:0098641	cadherin binding involved in cell-cell adhesion	4/665	18/18639	0.222222222222222	6.22857142857143	0.00329528064878804	0.122527693135163
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	5/665	29/18639	0.172413793103448	4.83251231527094	0.00332052283615513	0.122527693135163
GO:0097472	cyclin-dependent protein kinase activity	5/665	29/18639	0.172413793103448	4.83251231527094	0.00332052283615513	0.122527693135163
GO:0016922	nuclear receptor binding	12/665	137/18639	0.0875912408759124	2.45505735140772	0.00369572177327135	0.122527693135163
GO:0005096	GTPase activator activity	19/665	271/18639	0.0701107011070111	1.96510279388508	0.0040735376778885	0.122527693135163
GO:0004721	phosphoprotein phosphatase activity	14/665	175/18639	0.08	2.24228571428571	0.00410454243856847	0.122527693135163
GO:0004713	protein tyrosine kinase activity	12/665	140/18639	0.0857142857142857	2.40244897959184	0.00440221050107099	0.122527693135163
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	9/665	89/18639	0.101123595505618	2.83434991974318	0.00444636781435936	0.122527693135163
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	9/665	89/18639	0.101123595505618	2.83434991974318	0.00444636781435936	0.122527693135163
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	3/665	10/18639	0.3	8.40857142857143	0.00449618738168245	0.122527693135163
GO:0051864	histone H3K36 demethylase activity	3/665	10/18639	0.3	8.40857142857143	0.00449618738168245	0.122527693135163
GO:0008013	beta-catenin binding	10/665	106/18639	0.0943396226415094	2.64420485175202	0.00459352747047339	0.122527693135163
GO:0140793	histone H2AXY142 phosphatase activity	9/665	90/18639	0.1	2.80285714285714	0.00478834454009276	0.122527693135163
GO:0008432	JUN kinase binding	3/665	11/18639	0.272727272727273	7.64415584415584	0.00601964399792355	0.122527693135163
GO:1990948	ubiquitin ligase inhibitor activity	3/665	11/18639	0.272727272727273	7.64415584415584	0.00601964399792355	0.122527693135163
GO:0003714	transcription corepressor activity	15/665	204/18639	0.0735294117647059	2.0609243697479	0.00659818447000978	0.122527693135163
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	4/665	22/18639	0.181818181818182	5.0961038961039	0.00703629892184534	0.122527693135163
GO:0005004	GPI-linked ephrin receptor activity	6/665	49/18639	0.122448979591837	3.43206997084548	0.00765191344764135	0.122527693135163
GO:0005008	hepatocyte growth factor receptor activity	6/665	49/18639	0.122448979591837	3.43206997084548	0.00765191344764135	0.122527693135163
GO:0005009	insulin receptor activity	6/665	49/18639	0.122448979591837	3.43206997084548	0.00765191344764135	0.122527693135163
GO:0005011	macrophage colony-stimulating factor receptor activity	6/665	49/18639	0.122448979591837	3.43206997084548	0.00765191344764135	0.122527693135163
GO:0005018	platelet-derived growth factor alpha-receptor activity	6/665	49/18639	0.122448979591837	3.43206997084548	0.00765191344764135	0.122527693135163
GO:0005020	stem cell factor receptor activity	6/665	49/18639	0.122448979591837	3.43206997084548	0.00765191344764135	0.122527693135163
GO:0008288	boss receptor activity	6/665	49/18639	0.122448979591837	3.43206997084548	0.00765191344764135	0.122527693135163
GO:0035254	glutamate receptor binding	6/665	49/18639	0.122448979591837	3.43206997084548	0.00765191344764135	0.122527693135163
GO:0036332	placental growth factor receptor activity	6/665	49/18639	0.122448979591837	3.43206997084548	0.00765191344764135	0.122527693135163
GO:0038062	protein tyrosine kinase collagen receptor activity	6/665	49/18639	0.122448979591837	3.43206997084548	0.00765191344764135	0.122527693135163
GO:0060175	brain-derived neurotrophic factor receptor activity	6/665	49/18639	0.122448979591837	3.43206997084548	0.00765191344764135	0.122527693135163
GO:0003995	acyl-CoA dehydrogenase activity	3/665	12/18639	0.25	7.00714285714286	0.00781547486925977	0.122527693135163
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	3/665	12/18639	0.25	7.00714285714286	0.00781547486925977	0.122527693135163
GO:0097371	MDM2/MDM4 family protein binding	3/665	12/18639	0.25	7.00714285714286	0.00781547486925977	0.122527693135163
GO:0017124	SH3 domain binding	10/665	115/18639	0.0869565217391304	2.43726708074534	0.00809740452845223	0.122527693135163
GO:0033192	calmodulin-dependent protein phosphatase activity	8/665	81/18639	0.0987654320987654	2.76825396825397	0.00821215651308641	0.122527693135163
GO:0140791	histone H2AXS140 phosphatase activity	8/665	81/18639	0.0987654320987654	2.76825396825397	0.00821215651308641	0.122527693135163
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	8/665	81/18639	0.0987654320987654	2.76825396825397	0.00821215651308641	0.122527693135163
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	8/665	81/18639	0.0987654320987654	2.76825396825397	0.00821215651308641	0.122527693135163
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	8/665	81/18639	0.0987654320987654	2.76825396825397	0.00821215651308641	0.122527693135163
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	8/665	81/18639	0.0987654320987654	2.76825396825397	0.00821215651308641	0.122527693135163
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	8/665	81/18639	0.0987654320987654	2.76825396825397	0.00821215651308641	0.122527693135163
GO:1990439	MAP kinase serine/threonine phosphatase activity	8/665	81/18639	0.0987654320987654	2.76825396825397	0.00821215651308641	0.122527693135163
GO:0004725	protein tyrosine phosphatase activity	9/665	98/18639	0.0918367346938776	2.57405247813411	0.00831287987279414	0.122527693135163
GO:0005007	fibroblast growth factor receptor activity	6/665	50/18639	0.12	3.36342857142857	0.00843961382553096	0.122527693135163
GO:0005017	platelet-derived growth factor receptor activity	6/665	50/18639	0.12	3.36342857142857	0.00843961382553096	0.122527693135163
GO:0005019	platelet-derived growth factor beta-receptor activity	6/665	50/18639	0.12	3.36342857142857	0.00843961382553096	0.122527693135163
GO:0000287	magnesium ion binding	16/665	230/18639	0.0695652173913043	1.94981366459627	0.008581025192609	0.122527693135163
GO:0055106	ubiquitin-protein transferase regulator activity	5/665	36/18639	0.138888888888889	3.89285714285714	0.00859103270290418	0.122527693135163
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	8/665	82/18639	0.0975609756097561	2.73449477351916	0.00882401082249118	0.122527693135163
GO:0033549	MAP kinase phosphatase activity	8/665	82/18639	0.0975609756097561	2.73449477351916	0.00882401082249118	0.122527693135163
GO:0005030	neurotrophin receptor activity	6/665	51/18639	0.117647058823529	3.29747899159664	0.00928380888566575	0.12709665122348
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	8/665	83/18639	0.0963855421686747	2.70154905335628	0.00946928736169064	0.127835379382824
GO:0048027	mRNA 5'-UTR binding	4/665	24/18639	0.166666666666667	4.67142857142857	0.00966225274830537	0.128224733193162
GO:0031994	insulin-like growth factor I binding	3/665	13/18639	0.230769230769231	6.46813186813187	0.00989388373404027	0.128224733193162
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	3/665	13/18639	0.230769230769231	6.46813186813187	0.00989388373404027	0.128224733193162
GO:0017018	myosin phosphatase activity	8/665	84/18639	0.0952380952380952	2.66938775510204	0.0101490460695677	0.129800957626577
GO:0005109	frizzled binding	5/665	38/18639	0.131578947368421	3.68796992481203	0.0107919750385428	0.135472278177639
GO:0005003	ephrin receptor activity	6/665	53/18639	0.113207547169811	3.17304582210243	0.0111499817430155	0.135472278177639
GO:0005005	transmembrane-ephrin receptor activity	6/665	53/18639	0.113207547169811	3.17304582210243	0.0111499817430155	0.135472278177639
GO:0038064	collagen receptor activity	6/665	53/18639	0.113207547169811	3.17304582210243	0.0111499817430155	0.135472278177639
GO:0032454	histone H3K9 demethylase activity	3/665	14/18639	0.214285714285714	6.00612244897959	0.012262883953723	0.147154607444676
GO:0052742	phosphatidylinositol kinase activity	4/665	26/18639	0.153846153846154	4.31208791208791	0.012852736783594	0.152351953093334
GO:0032451	demethylase activity	5/665	40/18639	0.125	3.50357142857143	0.0133495338587803	0.156334300129331
GO:0001727	lipid kinase activity	5/665	41/18639	0.121951219512195	3.41811846689895	0.0147693521409802	0.164891857003765
GO:0017080	sodium channel regulator activity	5/665	41/18639	0.121951219512195	3.41811846689895	0.0147693521409802	0.164891857003765
GO:0005041	low-density lipoprotein particle receptor activity	3/665	15/18639	0.2	5.60571428571429	0.0149284808809993	0.164891857003765
GO:0031386	protein tag activity	3/665	15/18639	0.2	5.60571428571429	0.0149284808809993	0.164891857003765
GO:0141047	molecular tag activity	3/665	15/18639	0.2	5.60571428571429	0.0149284808809993	0.164891857003765
GO:0141052	histone H3 demethylase activity	4/665	28/18639	0.142857142857143	4.00408163265306	0.0166453225205147	0.180992509810222
GO:0005516	calmodulin binding	14/665	207/18639	0.0676328502415459	1.89565217391304	0.0167585657231687	0.180992509810222
GO:0005159	insulin-like growth factor receptor binding	3/665	16/18639	0.1875	5.25535714285714	0.0178948426479338	0.190076624550026
GO:0051213	dioxygenase activity	8/665	93/18639	0.0860215053763441	2.4110599078341	0.0179907916240765	0.190076624550026
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	6/665	60/18639	0.1	2.80285714285714	0.0197541525651096	0.206462755841791
GO:0042578	phosphoric ester hydrolase activity	21/665	363/18639	0.0578512396694215	1.62148760330579	0.0208988305909435	0.215587481109073
GO:0032452	histone demethylase activity	4/665	30/18639	0.133333333333333	3.73714285714286	0.021070792906751	0.215587481109073
GO:0072349	modified amino acid transmembrane transporter activity	4/665	31/18639	0.129032258064516	3.61658986175115	0.0235286109120523	0.23577123511871
GO:0140457	protein demethylase activity	4/665	31/18639	0.129032258064516	3.61658986175115	0.0235286109120523	0.23577123511871
GO:0019838	growth factor binding	10/665	136/18639	0.0735294117647059	2.0609243697479	0.0239458702413262	0.237503937495603
GO:0030228	lipoprotein particle receptor activity	3/665	18/18639	0.166666666666667	4.67142857142857	0.0247382958880508	0.240456236031854
GO:0031690	adrenergic receptor binding	3/665	18/18639	0.166666666666667	4.67142857142857	0.0247382958880508	0.240456236031854
GO:0001618	virus receptor activity	7/665	81/18639	0.0864197530864197	2.42222222222222	0.0254686797257518	0.245104521717136
GO:0140272	exogenous protein binding	7/665	82/18639	0.0853658536585366	2.39268292682927	0.0270221821567228	0.2575055005523
GO:0030295	protein kinase activator activity	10/665	139/18639	0.0719424460431655	2.01644398766701	0.0273358290660629	0.25796529953605
GO:0019843	rRNA binding	6/665	65/18639	0.0923076923076923	2.58725274725275	0.0281196418426801	0.260307541629381
GO:0038024	cargo receptor activity	6/665	65/18639	0.0923076923076923	2.58725274725275	0.0281196418426801	0.260307541629381
GO:0005520	insulin-like growth factor binding	3/665	19/18639	0.157894736842105	4.42556390977444	0.0286159250837363	0.262402633786714
GO:0004722	protein serine/threonine phosphatase activity	8/665	103/18639	0.0776699029126214	2.17697642163662	0.030965329050091	0.28129252183821
GO:0008376	acetylgalactosaminyltransferase activity	4/665	34/18639	0.117647058823529	3.29747899159664	0.0319094948857388	0.287185453971649
GO:0008514	organic anion transmembrane transporter activity	16/665	269/18639	0.0594795539033457	1.66712692511949	0.0323710222924771	0.288666363929245
GO:1990841	promoter-specific chromatin binding	6/665	68/18639	0.0882352941176471	2.47310924369748	0.0341150730187271	0.30145319067457
GO:0016791	phosphatase activity	16/665	273/18639	0.0586080586080586	1.64270015698587	0.0363070928223352	0.317932380390178
GO:0051010	microtubule plus-end binding	3/665	21/18639	0.142857142857143	4.00408163265306	0.0372746969147676	0.321035235736598
GO:0051015	actin filament binding	13/665	209/18639	0.062200956937799	1.7434039644566	0.0373219975702012	0.321035235736598
GO:0042826	histone deacetylase binding	9/665	127/18639	0.0708661417322835	1.98627671541057	0.0382129977200509	0.325816085823592
GO:0005496	steroid binding	8/665	108/18639	0.0740740740740741	2.07619047619048	0.0393945674650681	0.330756402916532
GO:0019209	kinase activator activity	10/665	148/18639	0.0675675675675676	1.89382239382239	0.039535593814081	0.330756402916532
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	9/665	128/18639	0.0703125	1.97075892857143	0.0398627941634571	0.330756402916532
GO:0019902	phosphatase binding	12/665	190/18639	0.0631578947368421	1.77022556390977	0.0401535550865748	0.330756402916532
GO:0003713	transcription coactivator activity	15/665	256/18639	0.05859375	1.64229910714286	0.0417803859733818	0.341265001396026
GO:0015485	cholesterol binding	5/665	54/18639	0.0925925925925926	2.5952380952381	0.042887448469888	0.344517354650671
GO:0051287	NAD binding	5/665	54/18639	0.0925925925925926	2.5952380952381	0.042887448469888	0.344517354650671
GO:0043539	protein serine/threonine kinase activator activity	6/665	73/18639	0.0821917808219178	2.30371819960861	0.0458280300074093	0.365121681698376
GO:0005158	insulin receptor binding	3/665	23/18639	0.130434782608696	3.65590062111801	0.0471143601681617	0.367822926853048
GO:0017134	fibroblast growth factor binding	3/665	23/18639	0.130434782608696	3.65590062111801	0.0471143601681617	0.367822926853048
GO:0004935	adrenergic receptor activity	2/665	10/18639	0.2	5.60571428571429	0.0473023311282212	0.367822926853048
GO:0042562	hormone binding	7/665	94/18639	0.074468085106383	2.08723404255319	0.0508383276020289	0.392181384358509
GO:0030215	semaphorin receptor binding	3/665	24/18639	0.125	3.50357142857143	0.0524646612281412	0.401540556801206
GO:0030331	nuclear estrogen receptor binding	4/665	40/18639	0.1	2.80285714285714	0.0532999124225249	0.404746209958549
GO:0005319	lipid transporter activity	11/665	178/18639	0.0617977528089888	1.73210272873194	0.0545821053192952	0.409825732700519
GO:0044325	transmembrane transporter binding	9/665	136/18639	0.0661764705882353	1.85483193277311	0.0548120835916332	0.409825732700519
GO:0034713	type I transforming growth factor beta receptor binding	2/665	11/18639	0.181818181818182	5.0961038961039	0.0564762616016207	0.415870653611934
GO:0050998	nitric-oxide synthase binding	2/665	11/18639	0.181818181818182	5.0961038961039	0.0564762616016207	0.415870653611934
GO:0015662	P-type ion transporter activity	3/665	25/18639	0.12	3.36342857142857	0.0580937846582085	0.421396706625214
GO:0140358	P-type transmembrane transporter activity	3/665	25/18639	0.12	3.36342857142857	0.0580937846582085	0.421396706625214
GO:0045309	protein phosphorylated amino acid binding	5/665	59/18639	0.0847457627118644	2.37530266343826	0.0588885947125271	0.423997881930195
GO:0042393	histone binding	14/665	247/18639	0.0566801619433198	1.58866396761134	0.0600351897570415	0.429075032675326
GO:0022853	active monoatomic ion transmembrane transporter activity	8/665	118/18639	0.0677966101694915	1.90024213075061	0.0605380995344964	0.429511187938179
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	3/665	26/18639	0.115384615384615	3.23406593406593	0.0639947909027234	0.447503142139907
GO:0008198	ferrous iron binding	3/665	26/18639	0.115384615384615	3.23406593406593	0.0639947909027234	0.447503142139907
GO:0005078	MAP-kinase scaffold activity	2/665	12/18639	0.166666666666667	4.67142857142857	0.0662084189480928	0.45320129026441
GO:0035259	nuclear glucocorticoid receptor binding	2/665	12/18639	0.166666666666667	4.67142857142857	0.0662084189480928	0.45320129026441
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	2/665	12/18639	0.166666666666667	4.67142857142857	0.0662084189480928	0.45320129026441
GO:0015101	organic cation transmembrane transporter activity	6/665	81/18639	0.0740740740740741	2.07619047619048	0.0692166283053568	0.470479459530117
GO:0004364	glutathione transferase activity	3/665	27/18639	0.111111111111111	3.11428571428571	0.0701601794315238	0.472812431566344
GO:0004857	enzyme inhibitor activity	21/665	416/18639	0.0504807692307692	1.41490384615385	0.0705790100308874	0.472812431566344
GO:0140297	DNA-binding transcription factor binding	24/665	488/18639	0.0491803278688525	1.37845433255269	0.0710191512435043	0.472812431566344
GO:0046943	carboxylic acid transmembrane transporter activity	11/665	188/18639	0.0585106382978723	1.63996960486322	0.0743292217636385	0.48972149551014
GO:0031625	ubiquitin protein ligase binding	16/665	302/18639	0.0529801324503311	1.48495742667928	0.0756577657624144	0.48972149551014
GO:0030165	PDZ domain binding	6/665	83/18639	0.072289156626506	2.02616179001721	0.0759692393860822	0.48972149551014
GO:0061459	L-arginine transmembrane transporter activity	2/665	13/18639	0.153846153846154	4.31208791208791	0.0764474253506478	0.48972149551014
GO:0005342	organic acid transmembrane transporter activity	11/665	189/18639	0.0582010582010582	1.6312925170068	0.0765238000644072	0.48972149551014
GO:0051019	mitogen-activated protein kinase binding	3/665	28/18639	0.107142857142857	3.0030612244898	0.0765819622608449	0.48972149551014
GO:0030246	carbohydrate binding	15/665	280/18639	0.0535714285714286	1.5015306122449	0.0776041886624158	0.493014845620053
GO:0051117	ATPase binding	6/665	84/18639	0.0714285714285714	2.00204081632653	0.0794807353686309	0.501657628430579
GO:0030276	clathrin binding	4/665	46/18639	0.0869565217391304	2.43726708074534	0.0807932533490874	0.506651885518148
GO:0120013	lipid transfer activity	5/665	65/18639	0.0769230769230769	2.15604395604396	0.0820033576762187	0.510943997828747
GO:0005543	phospholipid binding	24/665	497/18639	0.0482897384305835	1.35349238286864	0.0830835820074534	0.512156225218632
GO:0043236	laminin binding	3/665	29/18639	0.103448275862069	2.89950738916256	0.083251732082864	0.512156225218632
GO:0043495	protein-membrane adaptor activity	4/665	47/18639	0.0851063829787234	2.3854103343465	0.085943960951899	0.519661307651114
GO:0030983	mismatched DNA binding	2/665	14/18639	0.142857142857143	4.00408163265306	0.087144848916802	0.519661307651114
GO:0031404	chloride ion binding	2/665	14/18639	0.142857142857143	4.00408163265306	0.087144848916802	0.519661307651114
GO:0071933	Arp2/3 complex binding	2/665	14/18639	0.142857142857143	4.00408163265306	0.087144848916802	0.519661307651114
GO:1901474	azole transmembrane transporter activity	2/665	14/18639	0.142857142857143	4.00408163265306	0.087144848916802	0.519661307651114
GO:0019842	vitamin binding	9/665	150/18639	0.06	1.68171428571429	0.0888246963026261	0.526448809793613
GO:0033612	receptor serine/threonine kinase binding	3/665	30/18639	0.1	2.80285714285714	0.0901607253246544	0.528124189038664
GO:0050840	extracellular matrix binding	5/665	67/18639	0.0746268656716418	2.09168443496802	0.0906365565412615	0.528124189038664
GO:0035591	signaling adaptor activity	8/665	129/18639	0.062015503875969	1.73820598006645	0.0907373863883301	0.528124189038664
GO:0004197	cysteine-type endopeptidase activity	6/665	88/18639	0.0681818181818182	1.91103896103896	0.0944180463192885	0.542635896142618
GO:0030145	manganese ion binding	5/665	68/18639	0.0735294117647059	2.0609243697479	0.0951223885668593	0.542635896142618
GO:0032934	sterol binding	5/665	68/18639	0.0735294117647059	2.0609243697479	0.0951223885668593	0.542635896142618
GO:0022804	active transmembrane transporter activity	22/665	457/18639	0.0481400437636762	1.34929665520475	0.0961499664341834	0.542635896142618
GO:0001222	transcription corepressor binding	4/665	49/18639	0.0816326530612245	2.28804664723032	0.0967090392304853	0.542635896142618
GO:0010181	FMN binding	2/665	15/18639	0.133333333333333	3.73714285714286	0.0982550593838486	0.542635896142618
GO:0016846	carbon-sulfur lyase activity	2/665	15/18639	0.133333333333333	3.73714285714286	0.0982550593838486	0.542635896142618
GO:0050700	CARD domain binding	2/665	15/18639	0.133333333333333	3.73714285714286	0.0982550593838486	0.542635896142618
GO:0120283	protein serine/threonine kinase binding	2/665	15/18639	0.133333333333333	3.73714285714286	0.0982550593838486	0.542635896142618
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	23/665	484/18639	0.0475206611570248	1.33193624557261	0.10042407149417	0.551481341764594
GO:0042910	xenobiotic transmembrane transporter activity	3/665	32/18639	0.09375	2.62767857142857	0.104659891723649	0.571513566041498
GO:0072341	modified amino acid binding	6/665	91/18639	0.0659340659340659	1.84803767660911	0.106539525317748	0.57852747826174
GO:0016830	carbon-carbon lyase activity	4/665	51/18639	0.0784313725490196	2.19831932773109	0.108070950975764	0.579687542480602
GO:0005324	long-chain fatty acid transmembrane transporter activity	2/665	16/18639	0.125	3.50357142857143	0.109735090346122	0.579687542480602
GO:0005521	lamin binding	2/665	16/18639	0.125	3.50357142857143	0.109735090346122	0.579687542480602
GO:0070411	I-SMAD binding	2/665	16/18639	0.125	3.50357142857143	0.109735090346122	0.579687542480602
GO:0140327	flippase activity	2/665	16/18639	0.125	3.50357142857143	0.109735090346122	0.579687542480602
GO:0043178	alcohol binding	6/665	92/18639	0.0652173913043478	1.82795031055901	0.110750764678272	0.58189050414746
GO:0140416	transcription regulator inhibitor activity	3/665	33/18639	0.0909090909090909	2.54805194805195	0.112231258914053	0.583912218356867
GO:0001216	DNA-binding transcription activator activity	23/665	491/18639	0.0468431771894094	1.31294733779459	0.112337021432854	0.583912218356867
GO:0030159	signaling receptor complex adaptor activity	4/665	52/18639	0.0769230769230769	2.15604395604396	0.113967033068426	0.587106938317124
GO:0005518	collagen binding	5/665	72/18639	0.0694444444444444	1.94642857142857	0.114159682450552	0.587106938317124
GO:0044389	ubiquitin-like protein ligase binding	16/665	322/18639	0.0496894409937888	1.3927240461402	0.115022945047571	0.588433171506523
GO:0035401	histone H3Y41 kinase activity	7/665	115/18639	0.0608695652173913	1.70608695652174	0.117224654200072	0.593449811887863
GO:0140801	histone H2AXY142 kinase activity	7/665	115/18639	0.0608695652173913	1.70608695652174	0.117224654200072	0.593449811887863
GO:0008017	microtubule binding	14/665	276/18639	0.0507246376811594	1.42173913043478	0.119004898014304	0.596673037915984
GO:0099106	ion channel regulator activity	9/665	160/18639	0.05625	1.57660714285714	0.119355967043423	0.596673037915984
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	17/665	349/18639	0.0487106017191977	1.36528857961523	0.121510008365698	0.596673037915984
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	2/665	17/18639	0.117647058823529	3.29747899159664	0.121544507723626	0.596673037915984
GO:0032183	SUMO binding	2/665	17/18639	0.117647058823529	3.29747899159664	0.121544507723626	0.596673037915984
GO:1990226	histone methyltransferase binding	2/665	17/18639	0.117647058823529	3.29747899159664	0.121544507723626	0.596673037915984
GO:1990782	protein tyrosine kinase binding	7/665	117/18639	0.0598290598290598	1.67692307692308	0.125176731215927	0.611415993677794
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	4/665	54/18639	0.0740740740740741	2.07619047619048	0.126170713662217	0.613189668398375
GO:0061630	ubiquitin protein ligase activity	17/665	353/18639	0.0481586402266289	1.34981788749494	0.130573311379331	0.63059813711353
GO:0034185	apolipoprotein binding	2/665	18/18639	0.111111111111111	3.11428571428571	0.133645284203073	0.63059813711353
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	2/665	18/18639	0.111111111111111	3.11428571428571	0.133645284203073	0.63059813711353
GO:0070064	proline-rich region binding	2/665	18/18639	0.111111111111111	3.11428571428571	0.133645284203073	0.63059813711353
GO:1901611	phosphatidylglycerol binding	2/665	18/18639	0.111111111111111	3.11428571428571	0.133645284203073	0.63059813711353
GO:1990381	ubiquitin-specific protease binding	2/665	18/18639	0.111111111111111	3.11428571428571	0.133645284203073	0.63059813711353
GO:0016409	palmitoyltransferase activity	3/665	36/18639	0.0833333333333333	2.33571428571429	0.136116508066739	0.639155777009037
GO:0035091	phosphatidylinositol binding	14/665	284/18639	0.0492957746478873	1.38169014084507	0.139732012283771	0.650979965002584
GO:0015399	primary active transmembrane transporter activity	9/665	166/18639	0.0542168674698795	1.51962134251291	0.140094176334928	0.650979965002584
GO:0019903	protein phosphatase binding	8/665	144/18639	0.0555555555555556	1.55714285714286	0.143569304681563	0.650979965002584
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	2/665	19/18639	0.105263157894737	2.95037593984962	0.146001679393584	0.650979965002584
GO:0005346	purine ribonucleotide transmembrane transporter activity	2/665	19/18639	0.105263157894737	2.95037593984962	0.146001679393584	0.650979965002584
GO:0008301	DNA binding, bending	2/665	19/18639	0.105263157894737	2.95037593984962	0.146001679393584	0.650979965002584
GO:0008381	mechanosensitive monoatomic ion channel activity	2/665	19/18639	0.105263157894737	2.95037593984962	0.146001679393584	0.650979965002584
GO:0015245	fatty acid transmembrane transporter activity	2/665	19/18639	0.105263157894737	2.95037593984962	0.146001679393584	0.650979965002584
GO:0031420	alkali metal ion binding	2/665	19/18639	0.105263157894737	2.95037593984962	0.146001679393584	0.650979965002584
GO:0050145	nucleoside monophosphate kinase activity	2/665	19/18639	0.105263157894737	2.95037593984962	0.146001679393584	0.650979965002584
GO:1990380	K48-linked deubiquitinase activity	2/665	19/18639	0.105263157894737	2.95037593984962	0.146001679393584	0.650979965002584
GO:0016247	channel regulator activity	9/665	168/18639	0.0535714285714286	1.5015306122449	0.147392961031287	0.651820882193687
GO:0019207	kinase regulator activity	14/665	287/18639	0.0487804878048781	1.36724738675958	0.14798844517306	0.651820882193687
GO:0015631	tubulin binding	18/665	385/18639	0.0467532467532468	1.310426716141	0.148202073009058	0.651820882193687
GO:0141108	transporter regulator activity	9/665	170/18639	0.0529411764705882	1.48386554621849	0.154878446204471	0.677377682701704
GO:0048306	calcium-dependent protein binding	5/665	80/18639	0.0625	1.75178571428571	0.157100414122007	0.677377682701704
GO:0008238	exopeptidase activity	6/665	102/18639	0.0588235294117647	1.64873949579832	0.15727926682355	0.677377682701704
GO:0030742	GTP-dependent protein binding	2/665	20/18639	0.1	2.80285714285714	0.158580125450046	0.677377682701704
GO:0031418	L-ascorbic acid binding	2/665	20/18639	0.1	2.80285714285714	0.158580125450046	0.677377682701704
GO:0001786	phosphatidylserine binding	4/665	59/18639	0.0677966101694915	1.90024213075061	0.158891061374474	0.677377682701704
GO:0004879	nuclear receptor activity	4/665	59/18639	0.0677966101694915	1.90024213075061	0.158891061374474	0.677377682701704
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	4/665	60/18639	0.0666666666666667	1.86857142857143	0.165779974953266	0.700600589802498
GO:0098531	ligand-modulated transcription factor activity	4/665	60/18639	0.0666666666666667	1.86857142857143	0.165779974953266	0.700600589802498
GO:0016758	hexosyltransferase activity	10/665	197/18639	0.050761421319797	1.42277012327774	0.167621501893619	0.705316449526395
GO:0015144	carbohydrate transmembrane transporter activity	3/665	40/18639	0.075	2.10214285714286	0.170329371175926	0.708729117555212
GO:0005248	voltage-gated sodium channel activity	2/665	21/18639	0.0952380952380952	2.66938775510204	0.171349117927443	0.708729117555212
GO:0015174	basic amino acid transmembrane transporter activity	2/665	21/18639	0.0952380952380952	2.66938775510204	0.171349117927443	0.708729117555212
GO:0061891	calcium ion sensor activity	2/665	21/18639	0.0952380952380952	2.66938775510204	0.171349117927443	0.708729117555212
GO:0061659	ubiquitin-like protein ligase activity	17/665	372/18639	0.0456989247311828	1.28087557603687	0.178727683203402	0.73094463052279
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	3/665	41/18639	0.0731707317073171	2.05087108013937	0.179239686395164	0.73094463052279
GO:0008137	NADH dehydrogenase (ubiquinone) activity	3/665	41/18639	0.0731707317073171	2.05087108013937	0.179239686395164	0.73094463052279
GO:0008093	cytoskeletal anchor activity	2/665	22/18639	0.0909090909090909	2.54805194805195	0.184279111639349	0.73094463052279
GO:0061133	endopeptidase activator activity	2/665	22/18639	0.0909090909090909	2.54805194805195	0.184279111639349	0.73094463052279
GO:0140784	metal ion sensor activity	2/665	22/18639	0.0909090909090909	2.54805194805195	0.184279111639349	0.73094463052279
GO:0019894	kinesin binding	3/665	42/18639	0.0714285714285714	2.00204081632653	0.188273511323489	0.73094463052279
GO:0035198	miRNA binding	3/665	42/18639	0.0714285714285714	2.00204081632653	0.188273511323489	0.73094463052279
GO:0050660	flavin adenine dinucleotide binding	5/665	86/18639	0.0581395348837209	1.62956810631229	0.193000274143238	0.73094463052279
GO:0000295	adenine nucleotide transmembrane transporter activity	2/665	23/18639	0.0869565217391304	2.43726708074534	0.197342421303272	0.73094463052279
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	2/665	23/18639	0.0869565217391304	2.43726708074534	0.197342421303272	0.73094463052279
GO:0099186	structural constituent of postsynapse	2/665	23/18639	0.0869565217391304	2.43726708074534	0.197342421303272	0.73094463052279
GO:0141003	histone H2AX kinase activity	16/665	354/18639	0.0451977401129944	1.26682808716707	0.199090117409004	0.73094463052279
GO:0008081	phosphoric diester hydrolase activity	5/665	87/18639	0.0574712643678161	1.61083743842365	0.199247174395553	0.73094463052279
GO:0019887	protein kinase regulator activity	12/665	255/18639	0.0470588235294118	1.31899159663866	0.201793714185465	0.73094463052279
GO:0140658	ATP-dependent chromatin remodeler activity	8/665	158/18639	0.0506329113924051	1.41916817359855	0.203774174147725	0.73094463052279
GO:0001046	core promoter sequence-specific DNA binding	3/665	44/18639	0.0681818181818182	1.91103896103896	0.206673925476718	0.73094463052279
GO:0003954	NADH dehydrogenase activity	3/665	44/18639	0.0681818181818182	1.91103896103896	0.206673925476718	0.73094463052279
GO:0043014	alpha-tubulin binding	3/665	44/18639	0.0681818181818182	1.91103896103896	0.206673925476718	0.73094463052279
GO:0015297	antiporter activity	7/665	135/18639	0.0518518518518519	1.45333333333333	0.207821404560265	0.73094463052279
GO:0140996	histone H3 kinase activity	16/665	357/18639	0.0448179271708683	1.2561824729892	0.208193221100335	0.73094463052279
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	2/665	24/18639	0.0833333333333333	2.33571428571429	0.210513126764647	0.73094463052279
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	2/665	24/18639	0.0833333333333333	2.33571428571429	0.210513126764647	0.73094463052279
GO:0015149	hexose transmembrane transporter activity	2/665	24/18639	0.0833333333333333	2.33571428571429	0.210513126764647	0.73094463052279
GO:0050699	WW domain binding	2/665	24/18639	0.0833333333333333	2.33571428571429	0.210513126764647	0.73094463052279
GO:0055056	D-glucose transmembrane transporter activity	2/665	24/18639	0.0833333333333333	2.33571428571429	0.210513126764647	0.73094463052279
GO:0070300	phosphatidic acid binding	2/665	24/18639	0.0833333333333333	2.33571428571429	0.210513126764647	0.73094463052279
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/665	24/18639	0.0833333333333333	2.33571428571429	0.210513126764647	0.73094463052279
GO:0061135	endopeptidase regulator activity	9/665	184/18639	0.0489130434782609	1.37096273291925	0.212104001601401	0.73094463052279
GO:0046915	transition metal ion transmembrane transporter activity	3/665	45/18639	0.0666666666666667	1.86857142857143	0.216021992930734	0.73094463052279
GO:0140303	intramembrane lipid transporter activity	3/665	45/18639	0.0666666666666667	1.86857142857143	0.216021992930734	0.73094463052279
GO:0035173	histone kinase activity	16/665	360/18639	0.0444444444444444	1.24571428571429	0.217483381317702	0.73094463052279
GO:0000030	mannosyltransferase activity	2/665	25/18639	0.08	2.24228571428571	0.22376698259999	0.73094463052279
GO:0003707	nuclear steroid receptor activity	2/665	25/18639	0.08	2.24228571428571	0.22376698259999	0.73094463052279
GO:0005251	delayed rectifier potassium channel activity	2/665	25/18639	0.08	2.24228571428571	0.22376698259999	0.73094463052279
GO:0019706	protein-cysteine S-palmitoyltransferase activity	2/665	25/18639	0.08	2.24228571428571	0.22376698259999	0.73094463052279
GO:0019707	protein-cysteine S-acyltransferase activity	2/665	25/18639	0.08	2.24228571428571	0.22376698259999	0.73094463052279
GO:0120020	cholesterol transfer activity	2/665	25/18639	0.08	2.24228571428571	0.22376698259999	0.73094463052279
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	4/665	68/18639	0.0588235294117647	1.64873949579832	0.224271172225922	0.73094463052279
GO:0008234	cysteine-type peptidase activity	9/665	187/18639	0.0481283422459893	1.34896867838044	0.225354566401244	0.73094463052279
GO:0031406	carboxylic acid binding	9/665	187/18639	0.0481283422459893	1.34896867838044	0.225354566401244	0.73094463052279
GO:0030291	protein serine/threonine kinase inhibitor activity	3/665	46/18639	0.0652173913043478	1.82795031055901	0.22545655615736	0.73094463052279
GO:0015291	secondary active transmembrane transporter activity	13/665	287/18639	0.0452961672473868	1.2695868591339	0.227070865329973	0.73094463052279
GO:0001221	transcription coregulator binding	6/665	115/18639	0.0521739130434783	1.4623602484472	0.228041519830586	0.73094463052279
GO:0052689	carboxylic ester hydrolase activity	5/665	92/18639	0.0543478260869565	1.52329192546584	0.231447730381083	0.73094463052279
GO:0002039	p53 binding	4/665	69/18639	0.0579710144927536	1.62484472049689	0.231935909107938	0.73094463052279
GO:0009055	electron transfer activity	6/665	116/18639	0.0517241379310345	1.44975369458128	0.233871038208187	0.73094463052279
GO:0043177	organic acid binding	9/665	189/18639	0.0476190476190476	1.33469387755102	0.234357715994544	0.73094463052279
GO:0001784	phosphotyrosine residue binding	3/665	47/18639	0.0638297872340425	1.78905775075988	0.234968778557733	0.73094463052279
GO:0061749	forked DNA-dependent helicase activity	3/665	47/18639	0.0638297872340425	1.78905775075988	0.234968778557733	0.73094463052279
GO:1990518	single-stranded 3'-5' DNA helicase activity	3/665	47/18639	0.0638297872340425	1.78905775075988	0.234968778557733	0.73094463052279
GO:0004112	cyclic-nucleotide phosphodiesterase activity	2/665	26/18639	0.0769230769230769	2.15604395604396	0.237081331908095	0.73094463052279
GO:0005112	Notch binding	2/665	26/18639	0.0769230769230769	2.15604395604396	0.237081331908095	0.73094463052279
GO:0005160	transforming growth factor beta receptor binding	2/665	26/18639	0.0769230769230769	2.15604395604396	0.237081331908095	0.73094463052279
GO:0005227	calcium-activated cation channel activity	2/665	26/18639	0.0769230769230769	2.15604395604396	0.237081331908095	0.73094463052279
GO:0015145	monosaccharide transmembrane transporter activity	2/665	26/18639	0.0769230769230769	2.15604395604396	0.237081331908095	0.73094463052279
GO:0015216	purine nucleotide transmembrane transporter activity	2/665	26/18639	0.0769230769230769	2.15604395604396	0.237081331908095	0.73094463052279
GO:0030247	polysaccharide binding	2/665	26/18639	0.0769230769230769	2.15604395604396	0.237081331908095	0.73094463052279
GO:0030507	spectrin binding	2/665	26/18639	0.0769230769230769	2.15604395604396	0.237081331908095	0.73094463052279
GO:0034237	protein kinase A regulatory subunit binding	2/665	26/18639	0.0769230769230769	2.15604395604396	0.237081331908095	0.73094463052279
GO:0043548	phosphatidylinositol 3-kinase binding	2/665	26/18639	0.0769230769230769	2.15604395604396	0.237081331908095	0.73094463052279
GO:0050750	low-density lipoprotein particle receptor binding	2/665	26/18639	0.0769230769230769	2.15604395604396	0.237081331908095	0.73094463052279
GO:0051219	phosphoprotein binding	5/665	93/18639	0.0537634408602151	1.50691244239631	0.238061476495151	0.73094463052279
GO:0008028	monocarboxylic acid transmembrane transporter activity	4/665	70/18639	0.0571428571428571	1.60163265306122	0.239663815248979	0.73094463052279
GO:0097110	scaffold protein binding	4/665	70/18639	0.0571428571428571	1.60163265306122	0.239663815248979	0.73094463052279
GO:0009378	four-way junction helicase activity	3/665	48/18639	0.0625	1.75178571428571	0.244550014141756	0.73094463052279
GO:0016879	ligase activity, forming carbon-nitrogen bonds	3/665	48/18639	0.0625	1.75178571428571	0.244550014141756	0.73094463052279
GO:0036121	double-stranded DNA helicase activity	3/665	48/18639	0.0625	1.75178571428571	0.244550014141756	0.73094463052279
GO:0043138	3'-5' DNA helicase activity	3/665	48/18639	0.0625	1.75178571428571	0.244550014141756	0.73094463052279
GO:0140299	molecular sensor activity	4/665	71/18639	0.0563380281690141	1.57907444668008	0.247450339589549	0.73094463052279
GO:0008266	poly(U) RNA binding	2/665	27/18639	0.0740740740740741	2.07619047619048	0.250435024106221	0.73094463052279
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	2/665	27/18639	0.0740740740740741	2.07619047619048	0.250435024106221	0.73094463052279
GO:0004867	serine-type endopeptidase inhibitor activity	5/665	95/18639	0.0526315789473684	1.47518796992481	0.251440056025614	0.73094463052279
GO:0004842	ubiquitin-protein transferase activity	19/665	449/18639	0.0423162583518931	1.18606426980592	0.254152053040156	0.73094463052279
GO:0008194	UDP-glycosyltransferase activity	7/665	145/18639	0.0482758620689655	1.35310344827586	0.260749599487595	0.73094463052279
GO:0003697	single-stranded DNA binding	6/665	121/18639	0.0495867768595041	1.38984651711924	0.263667651503388	0.73094463052279
GO:0045499	chemorepellent activity	2/665	28/18639	0.0714285714285714	2.00204081632653	0.263808336555865	0.73094463052279
GO:0046875	ephrin receptor binding	2/665	28/18639	0.0714285714285714	2.00204081632653	0.263808336555865	0.73094463052279
GO:0046966	nuclear thyroid hormone receptor binding	2/665	28/18639	0.0714285714285714	2.00204081632653	0.263808336555865	0.73094463052279
GO:0050698	proteoglycan sulfotransferase activity	2/665	28/18639	0.0714285714285714	2.00204081632653	0.263808336555865	0.73094463052279
GO:0051119	sugar transmembrane transporter activity	2/665	28/18639	0.0714285714285714	2.00204081632653	0.263808336555865	0.73094463052279
GO:0015605	organophosphate ester transmembrane transporter activity	3/665	50/18639	0.06	1.68171428571429	0.263885948577886	0.73094463052279
GO:0003684	damaged DNA binding	4/665	74/18639	0.0540540540540541	1.51505791505792	0.271116676467776	0.73094463052279
GO:0035064	methylated histone binding	4/665	74/18639	0.0540540540540541	1.51505791505792	0.271116676467776	0.73094463052279
GO:0048029	monosaccharide binding	4/665	74/18639	0.0540540540540541	1.51505791505792	0.271116676467776	0.73094463052279
GO:0015085	calcium ion transmembrane transporter activity	7/665	147/18639	0.0476190476190476	1.33469387755102	0.271777568231882	0.73094463052279
GO:0042626	ATPase-coupled transmembrane transporter activity	5/665	98/18639	0.0510204081632653	1.43002915451895	0.271843317341612	0.73094463052279
GO:0008201	heparin binding	8/665	172/18639	0.0465116279069767	1.30365448504983	0.272193094437326	0.73094463052279
GO:0003785	actin monomer binding	2/665	29/18639	0.0689655172413793	1.93300492610837	0.277182899850161	0.73094463052279
GO:0016417	S-acyltransferase activity	2/665	29/18639	0.0689655172413793	1.93300492610837	0.277182899850161	0.73094463052279
GO:0140030	modification-dependent protein binding	8/665	173/18639	0.046242774566474	1.29611890999174	0.277320166960408	0.73094463052279
GO:1901681	sulfur compound binding	12/665	275/18639	0.0436363636363636	1.22306493506494	0.278519073513968	0.73094463052279
GO:0005080	protein kinase C binding	3/665	52/18639	0.0576923076923077	1.61703296703297	0.283399325899014	0.73094463052279
GO:0004674	protein serine/threonine kinase activity	18/665	433/18639	0.0415704387990762	1.16516001319696	0.285959270186627	0.73094463052279
GO:0016829	lyase activity	9/665	200/18639	0.045	1.26128571428571	0.285973369651831	0.73094463052279
GO:0140034	methylation-dependent protein binding	4/665	76/18639	0.0526315789473684	1.47518796992481	0.287105737454839	0.73094463052279
GO:0061134	peptidase regulator activity	10/665	226/18639	0.0442477876106195	1.24020227560051	0.288331072896688	0.73094463052279
GO:0008187	poly-pyrimidine tract binding	2/665	30/18639	0.0666666666666667	1.86857142857143	0.290541626601984	0.73094463052279
GO:0015215	nucleotide transmembrane transporter activity	2/665	30/18639	0.0666666666666667	1.86857142857143	0.290541626601984	0.73094463052279
GO:0022839	monoatomic ion-gated channel activity	2/665	30/18639	0.0666666666666667	1.86857142857143	0.290541626601984	0.73094463052279
GO:0031624	ubiquitin conjugating enzyme binding	2/665	30/18639	0.0666666666666667	1.86857142857143	0.290541626601984	0.73094463052279
GO:0035925	mRNA 3'-UTR AU-rich region binding	2/665	30/18639	0.0666666666666667	1.86857142857143	0.290541626601984	0.73094463052279
GO:0098918	structural constituent of synapse	2/665	30/18639	0.0666666666666667	1.86857142857143	0.290541626601984	0.73094463052279
GO:0001217	DNA-binding transcription repressor activity	12/665	278/18639	0.0431654676258993	1.20986639260021	0.290774283353569	0.73094463052279
GO:0005246	calcium channel regulator activity	3/665	53/18639	0.0566037735849057	1.58652291105121	0.29320319047852	0.73094463052279
GO:0005544	calcium-dependent phospholipid binding	3/665	53/18639	0.0566037735849057	1.58652291105121	0.29320319047852	0.73094463052279
GO:0017046	peptide hormone binding	3/665	53/18639	0.0566037735849057	1.58652291105121	0.29320319047852	0.73094463052279
GO:0051018	protein kinase A binding	3/665	53/18639	0.0566037735849057	1.58652291105121	0.29320319047852	0.73094463052279
GO:1901505	carbohydrate derivative transmembrane transporter activity	3/665	53/18639	0.0566037735849057	1.58652291105121	0.29320319047852	0.73094463052279
GO:0050661	NADP binding	3/665	54/18639	0.0555555555555556	1.55714285714286	0.303028630291244	0.73094463052279
GO:0140463	chromatin-protein adaptor activity	3/665	54/18639	0.0555555555555556	1.55714285714286	0.303028630291244	0.73094463052279
GO:0005310	dicarboxylic acid transmembrane transporter activity	2/665	31/18639	0.0645161290322581	1.80829493087558	0.303868643578652	0.73094463052279
GO:0005452	solute:inorganic anion antiporter activity	2/665	31/18639	0.0645161290322581	1.80829493087558	0.303868643578652	0.73094463052279
GO:0017147	Wnt-protein binding	2/665	31/18639	0.0645161290322581	1.80829493087558	0.303868643578652	0.73094463052279
GO:0070325	lipoprotein particle receptor binding	2/665	31/18639	0.0645161290322581	1.80829493087558	0.303868643578652	0.73094463052279
GO:0000182	rDNA binding	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0004445	inositol-polyphosphate 5-phosphatase activity	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0005381	iron ion transmembrane transporter activity	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0005522	profilin binding	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0008239	dipeptidyl-peptidase activity	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0015203	polyamine transmembrane transporter activity	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0015279	store-operated calcium channel activity	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0016303	1-phosphatidylinositol-3-kinase activity	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0016427	tRNA (cytidine) methyltransferase activity	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0016868	intramolecular phosphotransferase activity	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0019531	oxalate transmembrane transporter activity	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0030957	Tat protein binding	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0031419	cobalamin binding	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0042166	acetylcholine binding	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0042975	peroxisome proliferator activated receptor binding	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0043295	glutathione binding	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0043422	protein kinase B binding	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0045322	unmethylated CpG binding	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0050815	phosphoserine residue binding	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0051378	serotonin binding	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0051880	G-quadruplex DNA binding	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0070097	delta-catenin binding	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:1990763	arrestin family protein binding	1/665	10/18639	0.1	2.80285714285714	0.304683582316413	0.73094463052279
GO:0005085	guanyl-nucleotide exchange factor activity	10/665	230/18639	0.0434782608695652	1.21863354037267	0.306701100572613	0.73094463052279
GO:0031267	small GTPase binding	12/665	283/18639	0.0424028268551237	1.18849066128218	0.311534346903833	0.73094463052279
GO:0004386	helicase activity	7/665	155/18639	0.0451612903225806	1.2658064516129	0.316979876012171	0.73094463052279
GO:0071813	lipoprotein particle binding	2/665	32/18639	0.0625	1.75178571428571	0.317149227035652	0.73094463052279
GO:0071814	protein-lipid complex binding	2/665	32/18639	0.0625	1.75178571428571	0.317149227035652	0.73094463052279
GO:0120015	sterol transfer activity	2/665	32/18639	0.0625	1.75178571428571	0.317149227035652	0.73094463052279
GO:0016755	aminoacyltransferase activity	20/665	496/18639	0.0403225806451613	1.13018433179723	0.318701786932621	0.73094463052279
GO:0016798	hydrolase activity, acting on glycosyl bonds	6/665	130/18639	0.0461538461538462	1.29362637362637	0.319414040996114	0.73094463052279
GO:0170055	lipid transmembrane transporter activity	3/665	56/18639	0.0535714285714286	1.5015306122449	0.322715997010794	0.73094463052279
GO:0005262	calcium channel activity	6/665	131/18639	0.0458015267175573	1.28375136314068	0.325727214451841	0.73094463052279
GO:0030971	receptor tyrosine kinase binding	4/665	81/18639	0.0493827160493827	1.38412698412698	0.327570451298441	0.73094463052279
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0003953	NAD+ nucleosidase activity	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0004016	adenylate cyclase activity	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0004143	ATP-dependent diacylglycerol kinase activity	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0005536	D-glucose binding	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0008172	S-methyltransferase activity	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0008271	secondary active sulfate transmembrane transporter activity	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0008503	benzodiazepine receptor activity	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0008526	phosphatidylinositol transfer activity	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0010854	adenylate cyclase regulator activity	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0016594	glycine binding	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0019215	intermediate filament binding	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0032050	clathrin heavy chain binding	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0032404	mismatch repair complex binding	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0032794	GTPase activating protein binding	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0034056	estrogen response element binding	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0035252	UDP-xylosyltransferase activity	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0042285	xylosyltransferase activity	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0042608	T cell receptor binding	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0043522	leucine zipper domain binding	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0045294	alpha-catenin binding	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0047676	arachidonate-CoA ligase activity	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0048407	platelet-derived growth factor binding	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0050786	RAGE receptor binding	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0070697	activin receptor binding	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0070990	snRNP binding	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0097493	structural molecule activity conferring elasticity	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0140031	phosphorylation-dependent protein binding	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0140537	transcription regulator activator activity	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:1900750	oligopeptide binding	1/665	11/18639	0.0909090909090909	2.54805194805195	0.329504314387892	0.73094463052279
GO:0030296	protein tyrosine kinase activator activity	2/665	33/18639	0.0606060606060606	1.6987012987013	0.330369741108014	0.73094463052279
GO:0015932	nucleobase-containing compound transmembrane transporter activity	3/665	57/18639	0.0526315789473684	1.47518796992481	0.332564389117932	0.73094463052279
GO:0016504	peptidase activator activity	3/665	57/18639	0.0526315789473684	1.47518796992481	0.332564389117932	0.73094463052279
GO:1901981	phosphatidylinositol phosphate binding	8/665	185/18639	0.0432432432432432	1.21204633204633	0.340555296610988	0.73094463052279
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	3/665	58/18639	0.0517241379310345	1.44975369458128	0.342407288535663	0.73094463052279
GO:0017116	single-stranded DNA helicase activity	3/665	58/18639	0.0517241379310345	1.44975369458128	0.342407288535663	0.73094463052279
GO:0061980	regulatory RNA binding	3/665	58/18639	0.0517241379310345	1.44975369458128	0.342407288535663	0.73094463052279
GO:0030332	cyclin binding	2/665	34/18639	0.0588235294117647	1.64873949579832	0.343517579123997	0.73094463052279
GO:0052866	phosphatidylinositol phosphate phosphatase activity	2/665	34/18639	0.0588235294117647	1.64873949579832	0.343517579123997	0.73094463052279
GO:0051087	protein-folding chaperone binding	6/665	134/18639	0.0447761194029851	1.25501066098081	0.344760135241946	0.73094463052279
GO:0019787	ubiquitin-like protein transferase activity	19/665	479/18639	0.0396659707724426	1.11178049507903	0.35052838098094	0.73094463052279
GO:0004866	endopeptidase inhibitor activity	7/665	161/18639	0.0434782608695652	1.21863354037267	0.351701780803445	0.73094463052279
GO:0070888	E-box binding	3/665	59/18639	0.0508474576271186	1.42518159806295	0.352238514990726	0.73094463052279
GO:0000340	RNA 7-methylguanosine cap binding	1/665	12/18639	0.0833333333333333	2.33571428571429	0.353440304882419	0.73094463052279
GO:0004300	enoyl-CoA hydratase activity	1/665	12/18639	0.0833333333333333	2.33571428571429	0.353440304882419	0.73094463052279
GO:0004859	phospholipase inhibitor activity	1/665	12/18639	0.0833333333333333	2.33571428571429	0.353440304882419	0.73094463052279
GO:0005025	transforming growth factor beta receptor activity, type I	1/665	12/18639	0.0833333333333333	2.33571428571429	0.353440304882419	0.73094463052279
GO:0005026	transforming growth factor beta receptor activity, type II	1/665	12/18639	0.0833333333333333	2.33571428571429	0.353440304882419	0.73094463052279
GO:0005095	GTPase inhibitor activity	1/665	12/18639	0.0833333333333333	2.33571428571429	0.353440304882419	0.73094463052279
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	1/665	12/18639	0.0833333333333333	2.33571428571429	0.353440304882419	0.73094463052279
GO:0008504	monoamine transmembrane transporter activity	1/665	12/18639	0.0833333333333333	2.33571428571429	0.353440304882419	0.73094463052279
GO:0008603	cAMP-dependent protein kinase regulator activity	1/665	12/18639	0.0833333333333333	2.33571428571429	0.353440304882419	0.73094463052279
GO:0010853	cyclase activator activity	1/665	12/18639	0.0833333333333333	2.33571428571429	0.353440304882419	0.73094463052279
GO:0015132	prostaglandin transmembrane transporter activity	1/665	12/18639	0.0833333333333333	2.33571428571429	0.353440304882419	0.73094463052279
GO:0015269	calcium-activated potassium channel activity	1/665	12/18639	0.0833333333333333	2.33571428571429	0.353440304882419	0.73094463052279
GO:0015368	calcium:monoatomic cation antiporter activity	1/665	12/18639	0.0833333333333333	2.33571428571429	0.353440304882419	0.73094463052279
GO:0016361	activin receptor activity, type I	1/665	12/18639	0.0833333333333333	2.33571428571429	0.353440304882419	0.73094463052279
GO:0016362	activin receptor activity, type II	1/665	12/18639	0.0833333333333333	2.33571428571429	0.353440304882419	0.73094463052279
GO:0017002	activin receptor activity	1/665	12/18639	0.0833333333333333	2.33571428571429	0.353440304882419	0.73094463052279
GO:0017166	vinculin binding	1/665	12/18639	0.0833333333333333	2.33571428571429	0.353440304882419	0.73094463052279
GO:0031543	peptidyl-proline dioxygenase activity	1/665	12/18639	0.0833333333333333	2.33571428571429	0.353440304882419	0.73094463052279
GO:0035014	phosphatidylinositol 3-kinase regulator activity	1/665	12/18639	0.0833333333333333	2.33571428571429	0.353440304882419	0.73094463052279
GO:0043047	single-stranded telomeric DNA binding	1/665	12/18639	0.0833333333333333	2.33571428571429	0.353440304882419	0.73094463052279
GO:0045295	gamma-catenin binding	1/665	12/18639	0.0833333333333333	2.33571428571429	0.353440304882419	0.73094463052279
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	1/665	12/18639	0.0833333333333333	2.33571428571429	0.353440304882419	0.73094463052279
GO:0070410	co-SMAD binding	1/665	12/18639	0.0833333333333333	2.33571428571429	0.353440304882419	0.73094463052279
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	1/665	12/18639	0.0833333333333333	2.33571428571429	0.353440304882419	0.73094463052279
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	1/665	12/18639	0.0833333333333333	2.33571428571429	0.353440304882419	0.73094463052279
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	1/665	12/18639	0.0833333333333333	2.33571428571429	0.353440304882419	0.73094463052279
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	1/665	12/18639	0.0833333333333333	2.33571428571429	0.353440304882419	0.73094463052279
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	1/665	12/18639	0.0833333333333333	2.33571428571429	0.353440304882419	0.73094463052279
GO:0016757	glycosyltransferase activity	11/665	267/18639	0.0411985018726592	1.15473515248796	0.356329082606631	0.735354285124513
GO:0004869	cysteine-type endopeptidase inhibitor activity	2/665	36/18639	0.0555555555555556	1.55714285714286	0.369549613572936	0.742353751699361
GO:0044390	ubiquitin-like protein conjugating enzyme binding	2/665	36/18639	0.0555555555555556	1.55714285714286	0.369549613572936	0.742353751699361
GO:0001664	G protein-coupled receptor binding	12/665	297/18639	0.0404040404040404	1.13246753246753	0.371345202272242	0.742353751699361
GO:0015026	coreceptor activity	3/665	61/18639	0.0491803278688525	1.37845433255269	0.37184239743561	0.742353751699361
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	3/665	61/18639	0.0491803278688525	1.37845433255269	0.37184239743561	0.742353751699361
GO:0019905	syntaxin binding	3/665	61/18639	0.0491803278688525	1.37845433255269	0.37184239743561	0.742353751699361
GO:0005338	nucleotide-sugar transmembrane transporter activity	1/665	13/18639	0.0769230769230769	2.15604395604396	0.3765230448434	0.742353751699361
GO:0005542	folic acid binding	1/665	13/18639	0.0769230769230769	2.15604395604396	0.3765230448434	0.742353751699361
GO:0008035	high-density lipoprotein particle binding	1/665	13/18639	0.0769230769230769	2.15604395604396	0.3765230448434	0.742353751699361
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/665	13/18639	0.0769230769230769	2.15604395604396	0.3765230448434	0.742353751699361
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/665	13/18639	0.0769230769230769	2.15604395604396	0.3765230448434	0.742353751699361
GO:0019104	DNA N-glycosylase activity	1/665	13/18639	0.0769230769230769	2.15604395604396	0.3765230448434	0.742353751699361
GO:0031432	titin binding	1/665	13/18639	0.0769230769230769	2.15604395604396	0.3765230448434	0.742353751699361
GO:0043560	insulin receptor substrate binding	1/665	13/18639	0.0769230769230769	2.15604395604396	0.3765230448434	0.742353751699361
GO:0051011	microtubule minus-end binding	1/665	13/18639	0.0769230769230769	2.15604395604396	0.3765230448434	0.742353751699361
GO:0070123	transforming growth factor beta receptor activity, type III	1/665	13/18639	0.0769230769230769	2.15604395604396	0.3765230448434	0.742353751699361
GO:0070700	BMP receptor binding	1/665	13/18639	0.0769230769230769	2.15604395604396	0.3765230448434	0.742353751699361
GO:0071714	icosanoid transmembrane transporter activity	1/665	13/18639	0.0769230769230769	2.15604395604396	0.3765230448434	0.742353751699361
GO:0089720	caspase binding	1/665	13/18639	0.0769230769230769	2.15604395604396	0.3765230448434	0.742353751699361
GO:0140333	glycerophospholipid flippase activity	1/665	13/18639	0.0769230769230769	2.15604395604396	0.3765230448434	0.742353751699361
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	1/665	13/18639	0.0769230769230769	2.15604395604396	0.3765230448434	0.742353751699361
GO:1901338	catecholamine binding	1/665	13/18639	0.0769230769230769	2.15604395604396	0.3765230448434	0.742353751699361
GO:0016874	ligase activity	7/665	167/18639	0.0419161676646707	1.1748502994012	0.386785447655937	0.751195706780241
GO:0033218	amide binding	10/665	247/18639	0.0404858299595142	1.13475997686524	0.387226698960061	0.751195706780241
GO:1901682	sulfur compound transmembrane transporter activity	3/665	63/18639	0.0476190476190476	1.33469387755102	0.391331251666629	0.751195706780241
GO:0000146	microfilament motor activity	2/665	38/18639	0.0526315789473684	1.47518796992481	0.395163002685103	0.751195706780241
GO:0042887	amide transmembrane transporter activity	2/665	38/18639	0.0526315789473684	1.47518796992481	0.395163002685103	0.751195706780241
GO:0043531	ADP binding	2/665	38/18639	0.0526315789473684	1.47518796992481	0.395163002685103	0.751195706780241
GO:0030414	peptidase inhibitor activity	7/665	169/18639	0.0414201183431953	1.16094674556213	0.398509235085401	0.751195706780241
GO:0004065	arylsulfatase activity	1/665	14/18639	0.0714285714285714	2.00204081632653	0.398782906068523	0.751195706780241
GO:0005161	platelet-derived growth factor receptor binding	1/665	14/18639	0.0714285714285714	2.00204081632653	0.398782906068523	0.751195706780241
GO:0005347	ATP transmembrane transporter activity	1/665	14/18639	0.0714285714285714	2.00204081632653	0.398782906068523	0.751195706780241
GO:0005545	1-phosphatidylinositol binding	1/665	14/18639	0.0714285714285714	2.00204081632653	0.398782906068523	0.751195706780241
GO:0015926	glucosidase activity	1/665	14/18639	0.0714285714285714	2.00204081632653	0.398782906068523	0.751195706780241
GO:0019992	diacylglycerol binding	1/665	14/18639	0.0714285714285714	2.00204081632653	0.398782906068523	0.751195706780241
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/665	14/18639	0.0714285714285714	2.00204081632653	0.398782906068523	0.751195706780241
GO:0034236	protein kinase A catalytic subunit binding	1/665	14/18639	0.0714285714285714	2.00204081632653	0.398782906068523	0.751195706780241
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	1/665	14/18639	0.0714285714285714	2.00204081632653	0.398782906068523	0.751195706780241
GO:0042813	Wnt receptor activity	1/665	14/18639	0.0714285714285714	2.00204081632653	0.398782906068523	0.751195706780241
GO:0043176	amine binding	1/665	14/18639	0.0714285714285714	2.00204081632653	0.398782906068523	0.751195706780241
GO:0044548	S100 protein binding	1/665	14/18639	0.0714285714285714	2.00204081632653	0.398782906068523	0.751195706780241
GO:0046030	inositol trisphosphate phosphatase activity	1/665	14/18639	0.0714285714285714	2.00204081632653	0.398782906068523	0.751195706780241
GO:0098821	BMP receptor activity	1/665	14/18639	0.0714285714285714	2.00204081632653	0.398782906068523	0.751195706780241
GO:0098847	sequence-specific single stranded DNA binding	1/665	14/18639	0.0714285714285714	2.00204081632653	0.398782906068523	0.751195706780241
GO:1901612	cardiolipin binding	1/665	14/18639	0.0714285714285714	2.00204081632653	0.398782906068523	0.751195706780241
GO:0000217	DNA secondary structure binding	2/665	39/18639	0.0512820512820513	1.43736263736264	0.407790615707572	0.755831076615372
GO:0016776	phosphotransferase activity, phosphate group as acceptor	2/665	39/18639	0.0512820512820513	1.43736263736264	0.407790615707572	0.755831076615372
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	2/665	39/18639	0.0512820512820513	1.43736263736264	0.407790615707572	0.755831076615372
GO:0017171	serine hydrolase activity	8/665	198/18639	0.0404040404040404	1.13246753246753	0.411035190881565	0.755831076615372
GO:0000774	adenyl-nucleotide exchange factor activity	1/665	15/18639	0.0666666666666667	1.86857142857143	0.420249180831714	0.755831076615372
GO:0004129	cytochrome-c oxidase activity	1/665	15/18639	0.0666666666666667	1.86857142857143	0.420249180831714	0.755831076615372
GO:0004467	long-chain fatty acid-CoA ligase activity	1/665	15/18639	0.0666666666666667	1.86857142857143	0.420249180831714	0.755831076615372
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/665	15/18639	0.0666666666666667	1.86857142857143	0.420249180831714	0.755831076615372
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/665	15/18639	0.0666666666666667	1.86857142857143	0.420249180831714	0.755831076615372
GO:0008242	omega peptidase activity	1/665	15/18639	0.0666666666666667	1.86857142857143	0.420249180831714	0.755831076615372
GO:0015116	sulfate transmembrane transporter activity	1/665	15/18639	0.0666666666666667	1.86857142857143	0.420249180831714	0.755831076615372
GO:0015929	hexosaminidase activity	1/665	15/18639	0.0666666666666667	1.86857142857143	0.420249180831714	0.755831076615372
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/665	15/18639	0.0666666666666667	1.86857142857143	0.420249180831714	0.755831076615372
GO:0033130	acetylcholine receptor binding	1/665	15/18639	0.0666666666666667	1.86857142857143	0.420249180831714	0.755831076615372
GO:0034483	heparan sulfate sulfotransferase activity	1/665	15/18639	0.0666666666666667	1.86857142857143	0.420249180831714	0.755831076615372
GO:0045504	dynein heavy chain binding	1/665	15/18639	0.0666666666666667	1.86857142857143	0.420249180831714	0.755831076615372
GO:0047372	monoacylglycerol lipase activity	1/665	15/18639	0.0666666666666667	1.86857142857143	0.420249180831714	0.755831076615372
GO:0048531	beta-1,3-galactosyltransferase activity	1/665	15/18639	0.0666666666666667	1.86857142857143	0.420249180831714	0.755831076615372
GO:0050780	dopamine receptor binding	1/665	15/18639	0.0666666666666667	1.86857142857143	0.420249180831714	0.755831076615372
GO:0061578	K63-linked deubiquitinase activity	1/665	15/18639	0.0666666666666667	1.86857142857143	0.420249180831714	0.755831076615372
GO:0071855	neuropeptide receptor binding	2/665	40/18639	0.05	1.40142857142857	0.42028857594608	0.755831076615372
GO:0071949	FAD binding	2/665	40/18639	0.05	1.40142857142857	0.42028857594608	0.755831076615372
GO:0140097	catalytic activity, acting on DNA	13/665	336/18639	0.0386904761904762	1.0844387755102	0.422543554876594	0.755831076615372
GO:0032182	ubiquitin-like protein binding	5/665	120/18639	0.0416666666666667	1.16785714285714	0.427087977517439	0.755831076615372
GO:0005216	monoatomic ion channel activity	17/665	448/18639	0.0379464285714286	1.06358418367347	0.432309850969941	0.755831076615372
GO:0008227	G protein-coupled amine receptor activity	2/665	41/18639	0.0487804878048781	1.36724738675958	0.432650057461511	0.755831076615372
GO:0042169	SH2 domain binding	2/665	41/18639	0.0487804878048781	1.36724738675958	0.432650057461511	0.755831076615372
GO:0140318	protein transporter activity	2/665	41/18639	0.0487804878048781	1.36724738675958	0.432650057461511	0.755831076615372
GO:0022832	voltage-gated channel activity	7/665	175/18639	0.04	1.12114285714286	0.433622407612277	0.755831076615372
GO:0003777	microtubule motor activity	3/665	68/18639	0.0441176470588235	1.23655462184874	0.439289040256023	0.755831076615372
GO:0005548	phospholipid transporter activity	3/665	68/18639	0.0441176470588235	1.23655462184874	0.439289040256023	0.755831076615372
GO:0000062	fatty-acyl-CoA binding	1/665	16/18639	0.0625	1.75178571428571	0.44095012019742	0.755831076615372
GO:0005024	transforming growth factor beta receptor activity	1/665	16/18639	0.0625	1.75178571428571	0.44095012019742	0.755831076615372
GO:0015378	sodium:chloride symporter activity	1/665	16/18639	0.0625	1.75178571428571	0.44095012019742	0.755831076615372
GO:0016675	oxidoreductase activity, acting on a heme group of donors	1/665	16/18639	0.0625	1.75178571428571	0.44095012019742	0.755831076615372
GO:0022841	potassium ion leak channel activity	1/665	16/18639	0.0625	1.75178571428571	0.44095012019742	0.755831076615372
GO:0030275	LRR domain binding	1/665	16/18639	0.0625	1.75178571428571	0.44095012019742	0.755831076615372
GO:0031435	mitogen-activated protein kinase kinase kinase binding	1/665	16/18639	0.0625	1.75178571428571	0.44095012019742	0.755831076615372
GO:0034450	ubiquitin-ubiquitin ligase activity	1/665	16/18639	0.0625	1.75178571428571	0.44095012019742	0.755831076615372
GO:0055102	lipase inhibitor activity	1/665	16/18639	0.0625	1.75178571428571	0.44095012019742	0.755831076615372
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	1/665	16/18639	0.0625	1.75178571428571	0.44095012019742	0.755831076615372
GO:0097027	ubiquitin-protein transferase activator activity	1/665	16/18639	0.0625	1.75178571428571	0.44095012019742	0.755831076615372
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	1/665	16/18639	0.0625	1.75178571428571	0.44095012019742	0.755831076615372
GO:0140328	floppase activity	1/665	16/18639	0.0625	1.75178571428571	0.44095012019742	0.755831076615372
GO:0005261	monoatomic cation channel activity	13/665	341/18639	0.0381231671554252	1.0685379136992	0.44350385707739	0.755831076615372
GO:0048487	beta-tubulin binding	2/665	42/18639	0.0476190476190476	1.33469387755102	0.444868884768413	0.755831076615372
GO:0043021	ribonucleoprotein complex binding	7/665	177/18639	0.0395480225988701	1.10847457627119	0.445274400161413	0.755831076615372
GO:0051020	GTPase binding	12/665	315/18639	0.0380952380952381	1.06775510204082	0.449900152936511	0.755831076615372
GO:0000510	H3-H4 histone complex chaperone activity	6/665	151/18639	0.0397350993377483	1.11371807000946	0.453144261415097	0.755831076615372
GO:0140584	chromatin extrusion motor activity	6/665	151/18639	0.0397350993377483	1.11371807000946	0.453144261415097	0.755831076615372
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	6/665	151/18639	0.0397350993377483	1.11371807000946	0.453144261415097	0.755831076615372
GO:0140849	ATP-dependent H2AZ histone chaperone activity	6/665	151/18639	0.0397350993377483	1.11371807000946	0.453144261415097	0.755831076615372
GO:0005245	voltage-gated calcium channel activity	2/665	43/18639	0.0465116279069767	1.30365448504983	0.456939495232364	0.755831076615372
GO:0008375	acetylglucosaminyltransferase activity	2/665	43/18639	0.0465116279069767	1.30365448504983	0.456939495232364	0.755831076615372
GO:0015616	DNA translocase activity	6/665	152/18639	0.0394736842105263	1.10639097744361	0.459444024971304	0.755831076615372
GO:0140674	ATP-dependent histone chaperone activity	6/665	152/18639	0.0394736842105263	1.10639097744361	0.459444024971304	0.755831076615372
GO:0004029	aldehyde dehydrogenase (NAD+) activity	1/665	17/18639	0.0588235294117647	1.64873949579832	0.460912970977032	0.755831076615372
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	1/665	17/18639	0.0588235294117647	1.64873949579832	0.460912970977032	0.755831076615372
GO:0008429	phosphatidylethanolamine binding	1/665	17/18639	0.0588235294117647	1.64873949579832	0.460912970977032	0.755831076615372
GO:0008484	sulfuric ester hydrolase activity	1/665	17/18639	0.0588235294117647	1.64873949579832	0.460912970977032	0.755831076615372
GO:0009881	photoreceptor activity	1/665	17/18639	0.0588235294117647	1.64873949579832	0.460912970977032	0.755831076615372
GO:0015278	intracellularly gated calcium channel activity	1/665	17/18639	0.0588235294117647	1.64873949579832	0.460912970977032	0.755831076615372
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/665	17/18639	0.0588235294117647	1.64873949579832	0.460912970977032	0.755831076615372
GO:0019198	transmembrane receptor protein phosphatase activity	1/665	17/18639	0.0588235294117647	1.64873949579832	0.460912970977032	0.755831076615372
GO:0030169	low-density lipoprotein particle binding	1/665	17/18639	0.0588235294117647	1.64873949579832	0.460912970977032	0.755831076615372
GO:0030548	acetylcholine receptor regulator activity	1/665	17/18639	0.0588235294117647	1.64873949579832	0.460912970977032	0.755831076615372
GO:0038191	neuropilin binding	1/665	17/18639	0.0588235294117647	1.64873949579832	0.460912970977032	0.755831076615372
GO:0045125	bioactive lipid receptor activity	1/665	17/18639	0.0588235294117647	1.64873949579832	0.460912970977032	0.755831076615372
GO:0070402	NADPH binding	1/665	17/18639	0.0588235294117647	1.64873949579832	0.460912970977032	0.755831076615372
GO:0070403	NAD+ binding	1/665	17/18639	0.0588235294117647	1.64873949579832	0.460912970977032	0.755831076615372
GO:1901567	fatty acid derivative binding	1/665	17/18639	0.0588235294117647	1.64873949579832	0.460912970977032	0.755831076615372
GO:0022836	gated channel activity	12/665	318/18639	0.0377358490566038	1.05768194070081	0.462973434780534	0.755831076615372
GO:0061775	cohesin loader activity	6/665	153/18639	0.0392156862745098	1.09915966386555	0.465725862317337	0.755831076615372
GO:0019205	nucleobase-containing compound kinase activity	2/665	44/18639	0.0454545454545455	1.27402597402597	0.468856903315966	0.755831076615372
GO:0005506	iron ion binding	6/665	154/18639	0.038961038961039	1.09202226345083	0.471988419701253	0.755831076615372
GO:0008094	ATP-dependent activity, acting on DNA	8/665	210/18639	0.0380952380952381	1.06775510204082	0.47593432783723	0.755831076615372
GO:0004175	endopeptidase activity	15/665	405/18639	0.037037037037037	1.03809523809524	0.4784391389074	0.755831076615372
GO:0000900	mRNA regulatory element binding translation repressor activity	1/665	18/18639	0.0555555555555556	1.55714285714286	0.4801640113755	0.755831076615372
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	1/665	18/18639	0.0555555555555556	1.55714285714286	0.4801640113755	0.755831076615372
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/665	18/18639	0.0555555555555556	1.55714285714286	0.4801640113755	0.755831076615372
GO:0008525	phosphatidylcholine transporter activity	1/665	18/18639	0.0555555555555556	1.55714285714286	0.4801640113755	0.755831076615372
GO:0015280	ligand-gated sodium channel activity	1/665	18/18639	0.0555555555555556	1.55714285714286	0.4801640113755	0.755831076615372
GO:0015373	monoatomic anion:sodium symporter activity	1/665	18/18639	0.0555555555555556	1.55714285714286	0.4801640113755	0.755831076615372
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	1/665	18/18639	0.0555555555555556	1.55714285714286	0.4801640113755	0.755831076615372
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/665	18/18639	0.0555555555555556	1.55714285714286	0.4801640113755	0.755831076615372
GO:0017075	syntaxin-1 binding	1/665	18/18639	0.0555555555555556	1.55714285714286	0.4801640113755	0.755831076615372
GO:0017128	phospholipid scramblase activity	1/665	18/18639	0.0555555555555556	1.55714285714286	0.4801640113755	0.755831076615372
GO:0022851	GABA-gated chloride ion channel activity	1/665	18/18639	0.0555555555555556	1.55714285714286	0.4801640113755	0.755831076615372
GO:0032393	MHC class I receptor activity	1/665	18/18639	0.0555555555555556	1.55714285714286	0.4801640113755	0.755831076615372
GO:0035615	clathrin adaptor activity	1/665	18/18639	0.0555555555555556	1.55714285714286	0.4801640113755	0.755831076615372
GO:0050811	GABA receptor binding	1/665	18/18639	0.0555555555555556	1.55714285714286	0.4801640113755	0.755831076615372
GO:0099602	neurotransmitter receptor regulator activity	1/665	18/18639	0.0555555555555556	1.55714285714286	0.4801640113755	0.755831076615372
GO:0043130	ubiquitin binding	4/665	100/18639	0.04	1.12114285714286	0.480433755708175	0.755831076615372
GO:0051539	4 iron, 4 sulfur cluster binding	2/665	45/18639	0.0444444444444444	1.24571428571429	0.480616666589698	0.755831076615372
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	10/665	268/18639	0.0373134328358209	1.04584221748401	0.488000298603725	0.755831076615372
GO:0015078	proton transmembrane transporter activity	7/665	185/18639	0.0378378378378378	1.06054054054054	0.491374147465375	0.755831076615372
GO:0003678	DNA helicase activity	3/665	74/18639	0.0405405405405405	1.13629343629344	0.494801895028135	0.755831076615372
GO:0005539	glycosaminoglycan binding	9/665	242/18639	0.0371900826446281	1.04238488783943	0.497361032840636	0.755831076615372
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	1/665	19/18639	0.0526315789473684	1.47518796992481	0.498728585374496	0.755831076615372
GO:0004890	GABA-A receptor activity	1/665	19/18639	0.0526315789473684	1.47518796992481	0.498728585374496	0.755831076615372
GO:0022821	solute:potassium antiporter activity	1/665	19/18639	0.0526315789473684	1.47518796992481	0.498728585374496	0.755831076615372
GO:0022840	leak channel activity	1/665	19/18639	0.0526315789473684	1.47518796992481	0.498728585374496	0.755831076615372
GO:0022842	narrow pore channel activity	1/665	19/18639	0.0526315789473684	1.47518796992481	0.498728585374496	0.755831076615372
GO:0030506	ankyrin binding	1/665	19/18639	0.0526315789473684	1.47518796992481	0.498728585374496	0.755831076615372
GO:0043395	heparan sulfate proteoglycan binding	1/665	19/18639	0.0526315789473684	1.47518796992481	0.498728585374496	0.755831076615372
GO:0046624	sphingolipid transporter activity	1/665	19/18639	0.0526315789473684	1.47518796992481	0.498728585374496	0.755831076615372
GO:0097001	ceramide binding	1/665	19/18639	0.0526315789473684	1.47518796992481	0.498728585374496	0.755831076615372
GO:0120227	acyl-CoA binding	1/665	19/18639	0.0526315789473684	1.47518796992481	0.498728585374496	0.755831076615372
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	9/665	243/18639	0.037037037037037	1.03809523809524	0.502335108666945	0.755831076615372
GO:0003725	double-stranded RNA binding	3/665	75/18639	0.04	1.12114285714286	0.503789767520922	0.755831076615372
GO:0019003	GDP binding	3/665	75/18639	0.04	1.12114285714286	0.503789767520922	0.755831076615372
GO:0140597	protein carrier chaperone	7/665	188/18639	0.0372340425531915	1.0436170212766	0.50837618676674	0.755831076615372
GO:0003689	DNA clamp loader activity	6/665	160/18639	0.0375	1.05107142857143	0.509087022113938	0.755831076615372
GO:0004676	3-phosphoinositide-dependent protein kinase activity	9/665	245/18639	0.036734693877551	1.02962099125364	0.512240350579025	0.755831076615372
GO:0004711	ribosomal protein S6 kinase activity	9/665	245/18639	0.036734693877551	1.02962099125364	0.512240350579025	0.755831076615372
GO:0035175	histone H3S10 kinase activity	9/665	245/18639	0.036734693877551	1.02962099125364	0.512240350579025	0.755831076615372
GO:0035979	histone H2AXS139 kinase activity	9/665	245/18639	0.036734693877551	1.02962099125364	0.512240350579025	0.755831076615372
GO:0044022	histone H3S28 kinase activity	9/665	245/18639	0.036734693877551	1.02962099125364	0.512240350579025	0.755831076615372
GO:0044023	histone H4S1 kinase activity	9/665	245/18639	0.036734693877551	1.02962099125364	0.512240350579025	0.755831076615372
GO:0044024	histone H2AS1 kinase activity	9/665	245/18639	0.036734693877551	1.02962099125364	0.512240350579025	0.755831076615372
GO:0044025	histone H2BS14 kinase activity	9/665	245/18639	0.036734693877551	1.02962099125364	0.512240350579025	0.755831076615372
GO:0072354	histone H3T3 kinase activity	9/665	245/18639	0.036734693877551	1.02962099125364	0.512240350579025	0.755831076615372
GO:0072371	histone H2AS121 kinase activity	9/665	245/18639	0.036734693877551	1.02962099125364	0.512240350579025	0.755831076615372
GO:0072518	Rho-dependent protein serine/threonine kinase activity	9/665	245/18639	0.036734693877551	1.02962099125364	0.512240350579025	0.755831076615372
GO:0140823	histone H2BS36 kinase activity	9/665	245/18639	0.036734693877551	1.02962099125364	0.512240350579025	0.755831076615372
GO:0140855	histone H3S57 kinase activity	9/665	245/18639	0.036734693877551	1.02962099125364	0.512240350579025	0.755831076615372
GO:0140995	histone H2A kinase activity	9/665	245/18639	0.036734693877551	1.02962099125364	0.512240350579025	0.755831076615372
GO:0140997	histone H4 kinase activity	9/665	245/18639	0.036734693877551	1.02962099125364	0.512240350579025	0.755831076615372
GO:0140998	histone H2B kinase activity	9/665	245/18639	0.036734693877551	1.02962099125364	0.512240350579025	0.755831076615372
GO:1990244	histone H2AT120 kinase activity	9/665	245/18639	0.036734693877551	1.02962099125364	0.512240350579025	0.755831076615372
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	2/665	48/18639	0.0416666666666667	1.16785714285714	0.514913142665803	0.755831076615372
GO:0038187	pattern recognition receptor activity	2/665	48/18639	0.0416666666666667	1.16785714285714	0.514913142665803	0.755831076615372
GO:0140693	molecular condensate scaffold activity	2/665	48/18639	0.0416666666666667	1.16785714285714	0.514913142665803	0.755831076615372
GO:0000339	RNA cap binding	1/665	20/18639	0.05	1.40142857142857	0.516631135896835	0.755831076615372
GO:0001972	retinoic acid binding	1/665	20/18639	0.05	1.40142857142857	0.516631135896835	0.755831076615372
GO:0005326	neurotransmitter transmembrane transporter activity	1/665	20/18639	0.05	1.40142857142857	0.516631135896835	0.755831076615372
GO:0010851	cyclase regulator activity	1/665	20/18639	0.05	1.40142857142857	0.516631135896835	0.755831076615372
GO:0016408	C-acyltransferase activity	1/665	20/18639	0.05	1.40142857142857	0.516631135896835	0.755831076615372
GO:0016505	peptidase activator activity involved in apoptotic process	1/665	20/18639	0.05	1.40142857142857	0.516631135896835	0.755831076615372
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/665	20/18639	0.05	1.40142857142857	0.516631135896835	0.755831076615372
GO:0052745	inositol phosphate phosphatase activity	1/665	20/18639	0.05	1.40142857142857	0.516631135896835	0.755831076615372
GO:0061608	nuclear import signal receptor activity	1/665	20/18639	0.05	1.40142857142857	0.516631135896835	0.755831076615372
GO:0004677	DNA-dependent protein kinase activity	9/665	246/18639	0.0365853658536585	1.02543554006969	0.517170208455311	0.755831076615372
GO:0140857	histone H3T45 kinase activity	9/665	246/18639	0.0365853658536585	1.02543554006969	0.517170208455311	0.755831076615372
GO:0003724	RNA helicase activity	3/665	77/18639	0.038961038961039	1.09202226345083	0.521513935014084	0.755831076615372
GO:0035402	histone H3T11 kinase activity	9/665	247/18639	0.0364372469635627	1.02128397917872	0.522084038646308	0.755831076615372
GO:0035403	histone H3T6 kinase activity	9/665	247/18639	0.0364372469635627	1.02128397917872	0.522084038646308	0.755831076615372
GO:0016887	ATP hydrolysis activity	15/665	417/18639	0.0359712230215827	1.0082219938335	0.524418469585029	0.755831076615372
GO:0016763	pentosyltransferase activity	2/665	49/18639	0.0408163265306122	1.14402332361516	0.526007667168459	0.755831076615372
GO:0060590	ATPase regulator activity	2/665	49/18639	0.0408163265306122	1.14402332361516	0.526007667168459	0.755831076615372
GO:0000149	SNARE binding	4/665	106/18639	0.0377358490566038	1.05768194070081	0.526160565580113	0.755831076615372
GO:0106310	protein serine kinase activity	13/665	361/18639	0.03601108033241	1.00933913731698	0.526321132765792	0.755831076615372
GO:0004679	AMP-activated protein kinase activity	9/665	248/18639	0.0362903225806452	1.01716589861751	0.526981216969719	0.755831076615372
GO:0140713	histone chaperone activity	6/665	164/18639	0.0365853658536585	1.02543554006969	0.533278265504928	0.755831076615372
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	1/665	21/18639	0.0476190476190476	1.33469387755102	0.533895236795304	0.755831076615372
GO:0001846	opsonin binding	1/665	21/18639	0.0476190476190476	1.33469387755102	0.533895236795304	0.755831076615372
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	1/665	21/18639	0.0476190476190476	1.33469387755102	0.533895236795304	0.755831076615372
GO:0009975	cyclase activity	1/665	21/18639	0.0476190476190476	1.33469387755102	0.533895236795304	0.755831076615372
GO:0035613	RNA stem-loop binding	1/665	21/18639	0.0476190476190476	1.33469387755102	0.533895236795304	0.755831076615372
GO:0036122	BMP binding	1/665	21/18639	0.0476190476190476	1.33469387755102	0.533895236795304	0.755831076615372
GO:0051428	peptide hormone receptor binding	1/665	21/18639	0.0476190476190476	1.33469387755102	0.533895236795304	0.755831076615372
GO:0072542	protein phosphatase activator activity	1/665	21/18639	0.0476190476190476	1.33469387755102	0.533895236795304	0.755831076615372
GO:0140312	cargo adaptor activity	1/665	21/18639	0.0476190476190476	1.33469387755102	0.533895236795304	0.755831076615372
GO:0002020	protease binding	5/665	136/18639	0.0367647058823529	1.03046218487395	0.536545977192592	0.755831076615372
GO:0008186	ATP-dependent activity, acting on RNA	3/665	79/18639	0.0379746835443038	1.06437613019891	0.538887303456624	0.755831076615372
GO:0015103	inorganic anion transmembrane transporter activity	6/665	165/18639	0.0363636363636364	1.01922077922078	0.539248421536928	0.755831076615372
GO:0008236	serine-type peptidase activity	7/665	194/18639	0.0360824742268041	1.01134020618557	0.541766728640217	0.755831076615372
GO:0046873	metal ion transmembrane transporter activity	16/665	450/18639	0.0355555555555556	0.996571428571429	0.54186408651539	0.755831076615372
GO:0000049	tRNA binding	3/665	80/18639	0.0375	1.05107142857143	0.547437287997971	0.755831076615372
GO:0005272	sodium channel activity	2/665	51/18639	0.0392156862745098	1.09915966386555	0.547676549096742	0.755831076615372
GO:0016597	amino acid binding	2/665	51/18639	0.0392156862745098	1.09915966386555	0.547676549096742	0.755831076615372
GO:0004407	histone deacetylase activity	1/665	22/18639	0.0454545454545455	1.27402597402597	0.550543623707493	0.755831076615372
GO:0008970	phospholipase A1 activity	1/665	22/18639	0.0454545454545455	1.27402597402597	0.550543623707493	0.755831076615372
GO:0015377	chloride:monoatomic cation symporter activity	1/665	22/18639	0.0454545454545455	1.27402597402597	0.550543623707493	0.755831076615372
GO:0031683	G-protein beta/gamma-subunit complex binding	1/665	22/18639	0.0454545454545455	1.27402597402597	0.550543623707493	0.755831076615372
GO:0032931	histone H3K56 acetyltransferase activity	1/665	22/18639	0.0454545454545455	1.27402597402597	0.550543623707493	0.755831076615372
GO:0033558	protein lysine deacetylase activity	1/665	22/18639	0.0454545454545455	1.27402597402597	0.550543623707493	0.755831076615372
GO:0033691	sialic acid binding	1/665	22/18639	0.0454545454545455	1.27402597402597	0.550543623707493	0.755831076615372
GO:0043992	histone H3K9 acetyltransferase activity	1/665	22/18639	0.0454545454545455	1.27402597402597	0.550543623707493	0.755831076615372
GO:0043993	histone H3K18 acetyltransferase activity	1/665	22/18639	0.0454545454545455	1.27402597402597	0.550543623707493	0.755831076615372
GO:0043994	histone H3K23 acetyltransferase activity	1/665	22/18639	0.0454545454545455	1.27402597402597	0.550543623707493	0.755831076615372
GO:0043999	histone H2AK5 acetyltransferase activity	1/665	22/18639	0.0454545454545455	1.27402597402597	0.550543623707493	0.755831076615372
GO:0044012	histone H2AK9 acetyltransferase activity	1/665	22/18639	0.0454545454545455	1.27402597402597	0.550543623707493	0.755831076615372
GO:0044014	histone H2BK5 acetyltransferase activity	1/665	22/18639	0.0454545454545455	1.27402597402597	0.550543623707493	0.755831076615372
GO:0044015	histone H2BK12 acetyltransferase activity	1/665	22/18639	0.0454545454545455	1.27402597402597	0.550543623707493	0.755831076615372
GO:0044016	histone H3K4 acetyltransferase activity	1/665	22/18639	0.0454545454545455	1.27402597402597	0.550543623707493	0.755831076615372
GO:0044017	histone H3K27 acetyltransferase activity	1/665	22/18639	0.0454545454545455	1.27402597402597	0.550543623707493	0.755831076615372
GO:0044018	histone H3K36 acetyltransferase activity	1/665	22/18639	0.0454545454545455	1.27402597402597	0.550543623707493	0.755831076615372
GO:0046972	histone H4K16 acetyltransferase activity	1/665	22/18639	0.0454545454545455	1.27402597402597	0.550543623707493	0.755831076615372
GO:0050321	tau-protein kinase activity	1/665	22/18639	0.0454545454545455	1.27402597402597	0.550543623707493	0.755831076615372
GO:0070034	telomerase RNA binding	1/665	22/18639	0.0454545454545455	1.27402597402597	0.550543623707493	0.755831076615372
GO:0140908	histone H3K122 acetyltransferase activity	1/665	22/18639	0.0454545454545455	1.27402597402597	0.550543623707493	0.755831076615372
GO:0004222	metalloendopeptidase activity	4/665	110/18639	0.0363636363636364	1.01922077922078	0.555535446105988	0.761608538244034
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	1/665	23/18639	0.0434782608695652	1.21863354037267	0.566598223816776	0.76342482716357
GO:0004602	glutathione peroxidase activity	1/665	23/18639	0.0434782608695652	1.21863354037267	0.566598223816776	0.76342482716357
GO:0016849	phosphorus-oxygen lyase activity	1/665	23/18639	0.0434782608695652	1.21863354037267	0.566598223816776	0.76342482716357
GO:0016917	GABA receptor activity	1/665	23/18639	0.0434782608695652	1.21863354037267	0.566598223816776	0.76342482716357
GO:0042171	lysophosphatidic acid acyltransferase activity	1/665	23/18639	0.0434782608695652	1.21863354037267	0.566598223816776	0.76342482716357
GO:0043274	phospholipase binding	1/665	23/18639	0.0434782608695652	1.21863354037267	0.566598223816776	0.76342482716357
GO:0044013	histone H2B acetyltransferase activity	1/665	23/18639	0.0434782608695652	1.21863354037267	0.566598223816776	0.76342482716357
GO:0070577	lysine-acetylated histone binding	1/665	23/18639	0.0434782608695652	1.21863354037267	0.566598223816776	0.76342482716357
GO:0071617	lysophospholipid acyltransferase activity	1/665	23/18639	0.0434782608695652	1.21863354037267	0.566598223816776	0.76342482716357
GO:0140103	catalytic activity, acting on a glycoprotein	1/665	23/18639	0.0434782608695652	1.21863354037267	0.566598223816776	0.76342482716357
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	1/665	23/18639	0.0434782608695652	1.21863354037267	0.566598223816776	0.76342482716357
GO:0019001	guanyl nucleotide binding	14/665	400/18639	0.035	0.981	0.567812958032659	0.76342482716357
GO:0032561	guanyl ribonucleotide binding	14/665	400/18639	0.035	0.981	0.567812958032659	0.76342482716357
GO:0004864	protein phosphatase inhibitor activity	2/665	53/18639	0.0377358490566038	1.05768194070081	0.568641537928421	0.76342482716357
GO:0008146	sulfotransferase activity	2/665	53/18639	0.0377358490566038	1.05768194070081	0.568641537928421	0.76342482716357
GO:0005200	structural constituent of cytoskeleton	4/665	112/18639	0.0357142857142857	1.00102040816327	0.569852704590545	0.763995626016565
GO:0003925	G protein activity	2/665	54/18639	0.037037037037037	1.03809523809524	0.578857418991389	0.7656047894324
GO:0004860	protein kinase inhibitor activity	3/665	84/18639	0.0357142857142857	1.00102040816327	0.580685865722034	0.7656047894324
GO:0022843	voltage-gated monoatomic cation channel activity	5/665	143/18639	0.034965034965035	0.98001998001998	0.581371050089984	0.7656047894324
GO:0005315	phosphate transmembrane transporter activity	1/665	24/18639	0.0416666666666667	1.16785714285714	0.582080184558173	0.7656047894324
GO:0015295	solute:proton symporter activity	1/665	24/18639	0.0416666666666667	1.16785714285714	0.582080184558173	0.7656047894324
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/665	24/18639	0.0416666666666667	1.16785714285714	0.582080184558173	0.7656047894324
GO:0042625	ATPase-coupled ion transmembrane transporter activity	1/665	24/18639	0.0416666666666667	1.16785714285714	0.582080184558173	0.7656047894324
GO:0043998	histone H2A acetyltransferase activity	1/665	24/18639	0.0416666666666667	1.16785714285714	0.582080184558173	0.7656047894324
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	1/665	24/18639	0.0416666666666667	1.16785714285714	0.582080184558173	0.7656047894324
GO:0046961	proton-transporting ATPase activity, rotational mechanism	1/665	24/18639	0.0416666666666667	1.16785714285714	0.582080184558173	0.7656047894324
GO:0050431	transforming growth factor beta binding	1/665	24/18639	0.0416666666666667	1.16785714285714	0.582080184558173	0.7656047894324
GO:0070840	dynein complex binding	1/665	24/18639	0.0416666666666667	1.16785714285714	0.582080184558173	0.7656047894324
GO:0140033	acetylation-dependent protein binding	1/665	24/18639	0.0416666666666667	1.16785714285714	0.582080184558173	0.7656047894324
GO:0140612	DNA damage sensor activity	1/665	24/18639	0.0416666666666667	1.16785714285714	0.582080184558173	0.7656047894324
GO:0005244	voltage-gated monoatomic ion channel activity	6/665	173/18639	0.0346820809248555	0.972089182493807	0.5857447408319	0.769383632552171
GO:0019955	cytokine binding	5/665	144/18639	0.0347222222222222	0.973214285714286	0.587583530935076	0.769825552446858
GO:0008374	O-acyltransferase activity	2/665	55/18639	0.0363636363636364	1.01922077922078	0.588894735656957	0.769825552446858
GO:0140313	molecular sequestering activity	2/665	55/18639	0.0363636363636364	1.01922077922078	0.588894735656957	0.769825552446858
GO:0005525	GTP binding	13/665	378/18639	0.0343915343915344	0.963945578231292	0.593659956356032	0.769825552446858
GO:0004709	MAP kinase kinase kinase activity	1/665	25/18639	0.04	1.12114285714286	0.59700990130643	0.769825552446858
GO:0008139	nuclear localization sequence binding	1/665	25/18639	0.04	1.12114285714286	0.59700990130643	0.769825552446858
GO:0015271	outward rectifier potassium channel activity	1/665	25/18639	0.04	1.12114285714286	0.59700990130643	0.769825552446858
GO:0015296	monoatomic anion:monoatomic cation symporter activity	1/665	25/18639	0.04	1.12114285714286	0.59700990130643	0.769825552446858
GO:0015645	fatty acid ligase activity	1/665	25/18639	0.04	1.12114285714286	0.59700990130643	0.769825552446858
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/665	25/18639	0.04	1.12114285714286	0.59700990130643	0.769825552446858
GO:0019211	phosphatase activator activity	1/665	25/18639	0.04	1.12114285714286	0.59700990130643	0.769825552446858
GO:0042974	nuclear retinoic acid receptor binding	1/665	25/18639	0.04	1.12114285714286	0.59700990130643	0.769825552446858
GO:0120515	fatty acid-CoA ligase activity	1/665	25/18639	0.04	1.12114285714286	0.59700990130643	0.769825552446858
GO:0019212	phosphatase inhibitor activity	2/665	56/18639	0.0357142857142857	1.00102040816327	0.598753207458667	0.769825552446858
GO:0030170	pyridoxal phosphate binding	2/665	56/18639	0.0357142857142857	1.00102040816327	0.598753207458667	0.769825552446858
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	2/665	56/18639	0.0357142857142857	1.00102040816327	0.598753207458667	0.769825552446858
GO:0015293	symporter activity	5/665	146/18639	0.0342465753424658	0.959882583170254	0.599856100185838	0.770224741586042
GO:0004252	serine-type endopeptidase activity	6/665	176/18639	0.0340909090909091	0.95551948051948	0.602547324203807	0.772659629453959
GO:0070279	vitamin B6 binding	2/665	57/18639	0.0350877192982456	0.983458646616541	0.608432800852876	0.776846597187003
GO:0004435	phosphatidylinositol phospholipase C activity	1/665	26/18639	0.0384615384615385	1.07802197802198	0.611407044082364	0.776846597187003
GO:0008143	poly(A) binding	1/665	26/18639	0.0384615384615385	1.07802197802198	0.611407044082364	0.776846597187003
GO:0008157	protein phosphatase 1 binding	1/665	26/18639	0.0384615384615385	1.07802197802198	0.611407044082364	0.776846597187003
GO:0070006	metalloaminopeptidase activity	1/665	26/18639	0.0384615384615385	1.07802197802198	0.611407044082364	0.776846597187003
GO:0070412	R-SMAD binding	1/665	26/18639	0.0384615384615385	1.07802197802198	0.611407044082364	0.776846597187003
GO:0120014	phospholipid transfer activity	1/665	26/18639	0.0384615384615385	1.07802197802198	0.611407044082364	0.776846597187003
GO:0016651	oxidoreductase activity, acting on NAD(P)H	3/665	88/18639	0.0340909090909091	0.95551948051948	0.612348466672901	0.777027036039242
GO:0008509	monoatomic anion transmembrane transporter activity	5/665	149/18639	0.0335570469798658	0.940556088207095	0.617872543652211	0.783014488174641
GO:0005044	scavenger receptor activity	1/665	27/18639	0.037037037037037	1.03809523809524	0.625290583312215	0.788105501129735
GO:0016405	CoA-ligase activity	1/665	27/18639	0.037037037037037	1.03809523809524	0.625290583312215	0.788105501129735
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	1/665	27/18639	0.037037037037037	1.03809523809524	0.625290583312215	0.788105501129735
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	1/665	27/18639	0.037037037037037	1.03809523809524	0.625290583312215	0.788105501129735
GO:0015459	potassium channel regulator activity	2/665	59/18639	0.0338983050847458	0.950121065375303	0.627256350498863	0.788105501129735
GO:0031593	polyubiquitin modification-dependent protein binding	2/665	59/18639	0.0338983050847458	0.950121065375303	0.627256350498863	0.788105501129735
GO:0019210	kinase inhibitor activity	3/665	90/18639	0.0333333333333333	0.934285714285714	0.627565491640344	0.788105501129735
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	6/665	181/18639	0.0331491712707182	0.929123914759274	0.629710605079054	0.789778978241084
GO:0015108	chloride transmembrane transporter activity	4/665	121/18639	0.0330578512396694	0.926564344746163	0.630942770094516	0.790304603778183
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	3/665	91/18639	0.032967032967033	0.924018838304553	0.635018143873718	0.792842666491318
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	4/665	122/18639	0.0327868852459016	0.918969555035129	0.637376181997686	0.792842666491318
GO:0016866	intramolecular transferase activity	1/665	28/18639	0.0357142857142857	1.00102040816327	0.638678814673561	0.792842666491318
GO:0019789	SUMO transferase activity	1/665	28/18639	0.0357142857142857	1.00102040816327	0.638678814673561	0.792842666491318
GO:0036408	histone H3K14 acetyltransferase activity	1/665	28/18639	0.0357142857142857	1.00102040816327	0.638678814673561	0.792842666491318
GO:0046625	sphingolipid binding	1/665	28/18639	0.0357142857142857	1.00102040816327	0.638678814673561	0.792842666491318
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	1/665	28/18639	0.0357142857142857	1.00102040816327	0.638678814673561	0.792842666491318
GO:0003774	cytoskeletal motor activity	5/665	153/18639	0.0326797385620915	0.915966386554622	0.641134401406843	0.794875813989097
GO:0005267	potassium channel activity	4/665	124/18639	0.032258064516129	0.904147465437788	0.650022771650699	0.800688849980314
GO:0004629	phospholipase C activity	1/665	29/18639	0.0344827586206897	0.966502463054187	0.651589383060111	0.800688849980314
GO:0010484	histone H3 acetyltransferase activity	1/665	29/18639	0.0344827586206897	0.966502463054187	0.651589383060111	0.800688849980314
GO:0035250	UDP-galactosyltransferase activity	1/665	29/18639	0.0344827586206897	0.966502463054187	0.651589383060111	0.800688849980314
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	1/665	29/18639	0.0344827586206897	0.966502463054187	0.651589383060111	0.800688849980314
GO:0099604	ligand-gated calcium channel activity	1/665	29/18639	0.0344827586206897	0.966502463054187	0.651589383060111	0.800688849980314
GO:0106222	lncRNA binding	1/665	29/18639	0.0344827586206897	0.966502463054187	0.651589383060111	0.800688849980314
GO:0015179	L-amino acid transmembrane transporter activity	2/665	62/18639	0.032258064516129	0.904147465437788	0.654161608580814	0.80283470144009
GO:0005507	copper ion binding	2/665	63/18639	0.0317460317460317	0.889795918367347	0.662778997332099	0.805800505789131
GO:0001965	G-protein alpha-subunit binding	1/665	30/18639	0.0333333333333333	0.934285714285714	0.664039305696599	0.805800505789131
GO:0001968	fibronectin binding	1/665	30/18639	0.0333333333333333	0.934285714285714	0.664039305696599	0.805800505789131
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	1/665	30/18639	0.0333333333333333	0.934285714285714	0.664039305696599	0.805800505789131
GO:0031210	phosphatidylcholine binding	1/665	30/18639	0.0333333333333333	0.934285714285714	0.664039305696599	0.805800505789131
GO:0043995	histone H4K5 acetyltransferase activity	1/665	30/18639	0.0333333333333333	0.934285714285714	0.664039305696599	0.805800505789131
GO:0043996	histone H4K8 acetyltransferase activity	1/665	30/18639	0.0333333333333333	0.934285714285714	0.664039305696599	0.805800505789131
GO:0043997	histone H4K12 acetyltransferase activity	1/665	30/18639	0.0333333333333333	0.934285714285714	0.664039305696599	0.805800505789131
GO:0051721	protein phosphatase 2A binding	1/665	30/18639	0.0333333333333333	0.934285714285714	0.664039305696599	0.805800505789131
GO:0140104	molecular carrier activity	8/665	249/18639	0.0321285140562249	0.900516351118761	0.667954149395154	0.809540440414077
GO:0008327	methyl-CpG binding	1/665	31/18639	0.032258064516129	0.904147465437788	0.676044994433864	0.815280067729175
GO:0016411	acylglycerol O-acyltransferase activity	1/665	31/18639	0.032258064516129	0.904147465437788	0.676044994433864	0.815280067729175
GO:0016878	acid-thiol ligase activity	1/665	31/18639	0.032258064516129	0.904147465437788	0.676044994433864	0.815280067729175
GO:0047499	calcium-independent phospholipase A2 activity	1/665	31/18639	0.032258064516129	0.904147465437788	0.676044994433864	0.815280067729175
GO:0015079	potassium ion transmembrane transporter activity	5/665	160/18639	0.03125	0.875892857142857	0.679663085115498	0.817076838007423
GO:0005249	voltage-gated potassium channel activity	3/665	98/18639	0.0306122448979592	0.85801749271137	0.684249316643793	0.817076838007423
GO:0016298	lipase activity	4/665	130/18639	0.0307692307692308	0.862417582417582	0.686173967156558	0.817076838007423
GO:0008378	galactosyltransferase activity	1/665	32/18639	0.03125	0.875892857142857	0.687622277253161	0.817076838007423
GO:0015106	bicarbonate transmembrane transporter activity	1/665	32/18639	0.03125	0.875892857142857	0.687622277253161	0.817076838007423
GO:0030515	snoRNA binding	1/665	32/18639	0.03125	0.875892857142857	0.687622277253161	0.817076838007423
GO:0031369	translation initiation factor binding	1/665	32/18639	0.03125	0.875892857142857	0.687622277253161	0.817076838007423
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1/665	32/18639	0.03125	0.875892857142857	0.687622277253161	0.817076838007423
GO:0043425	bHLH transcription factor binding	1/665	32/18639	0.03125	0.875892857142857	0.687622277253161	0.817076838007423
GO:0047498	calcium-dependent phospholipase A2 activity	1/665	32/18639	0.03125	0.875892857142857	0.687622277253161	0.817076838007423
GO:0070717	poly-purine tract binding	1/665	32/18639	0.03125	0.875892857142857	0.687622277253161	0.817076838007423
GO:0140142	nucleocytoplasmic carrier activity	1/665	32/18639	0.03125	0.875892857142857	0.687622277253161	0.817076838007423
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	4/665	132/18639	0.0303030303030303	0.849350649350649	0.697622095457457	0.825298176519418
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	1/665	33/18639	0.0303030303030303	0.849350649350649	0.698786419007696	0.825298176519418
GO:0019956	chemokine binding	1/665	33/18639	0.0303030303030303	0.849350649350649	0.698786419007696	0.825298176519418
GO:0071889	14-3-3 protein binding	1/665	33/18639	0.0303030303030303	0.849350649350649	0.698786419007696	0.825298176519418
GO:0140311	protein sequestering activity	1/665	33/18639	0.0303030303030303	0.849350649350649	0.698786419007696	0.825298176519418
GO:0008175	tRNA methyltransferase activity	1/665	34/18639	0.0294117647058824	0.82436974789916	0.709552141428415	0.832514358528823
GO:0015020	glucuronosyltransferase activity	1/665	34/18639	0.0294117647058824	0.82436974789916	0.709552141428415	0.832514358528823
GO:0015035	protein-disulfide reductase activity	1/665	34/18639	0.0294117647058824	0.82436974789916	0.709552141428415	0.832514358528823
GO:0016831	carboxy-lyase activity	1/665	34/18639	0.0294117647058824	0.82436974789916	0.709552141428415	0.832514358528823
GO:0051427	hormone receptor binding	1/665	34/18639	0.0294117647058824	0.82436974789916	0.709552141428415	0.832514358528823
GO:0015171	amino acid transmembrane transporter activity	3/665	102/18639	0.0294117647058824	0.82436974789916	0.710073754672769	0.832514358528823
GO:0098960	postsynaptic neurotransmitter receptor activity	2/665	69/18639	0.0289855072463768	0.812422360248447	0.710891890513295	0.832514358528823
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	7/665	229/18639	0.0305676855895196	0.856768558951965	0.713147292982417	0.834150624282683
GO:0016782	transferase activity, transferring sulphur-containing groups	2/665	70/18639	0.0285714285714286	0.800816326530612	0.718327691799279	0.835054296458624
GO:0000175	3'-5'-RNA exonuclease activity	1/665	35/18639	0.0285714285714286	0.800816326530612	0.719933642420089	0.835054296458624
GO:0004623	phospholipase A2 activity	1/665	35/18639	0.0285714285714286	0.800816326530612	0.719933642420089	0.835054296458624
GO:0005154	epidermal growth factor receptor binding	1/665	35/18639	0.0285714285714286	0.800816326530612	0.719933642420089	0.835054296458624
GO:0010485	histone H4 acetyltransferase activity	1/665	35/18639	0.0285714285714286	0.800816326530612	0.719933642420089	0.835054296458624
GO:0016229	steroid dehydrogenase activity	1/665	35/18639	0.0285714285714286	0.800816326530612	0.719933642420089	0.835054296458624
GO:0043015	gamma-tubulin binding	1/665	35/18639	0.0285714285714286	0.800816326530612	0.719933642420089	0.835054296458624
GO:0003730	mRNA 3'-UTR binding	8/665	262/18639	0.0305343511450382	0.855834242093784	0.721606101216306	0.835996579716627
GO:0000993	RNA polymerase II complex binding	1/665	36/18639	0.0277777777777778	0.778571428571429	0.729944614672865	0.842643901973901
GO:0004190	aspartic-type endopeptidase activity	1/665	36/18639	0.0277777777777778	0.778571428571429	0.729944614672865	0.842643901973901
GO:0045505	dynein intermediate chain binding	1/665	36/18639	0.0277777777777778	0.778571428571429	0.729944614672865	0.842643901973901
GO:0140767	enzyme-substrate adaptor activity	4/665	139/18639	0.0287769784172662	0.806577595066804	0.735314133818418	0.847244623915173
GO:0019213	deacetylase activity	1/665	37/18639	0.027027027027027	0.757528957528958	0.739598263613495	0.847244623915173
GO:0030280	structural constituent of skin epidermis	1/665	37/18639	0.027027027027027	0.757528957528958	0.739598263613495	0.847244623915173
GO:0030551	cyclic nucleotide binding	1/665	37/18639	0.027027027027027	0.757528957528958	0.739598263613495	0.847244623915173
GO:0043394	proteoglycan binding	1/665	37/18639	0.027027027027027	0.757528957528958	0.739598263613495	0.847244623915173
GO:0070001	aspartic-type peptidase activity	1/665	37/18639	0.027027027027027	0.757528957528958	0.739598263613495	0.847244623915173
GO:0019888	protein phosphatase regulator activity	3/665	107/18639	0.0280373831775701	0.78584779706275	0.740031569654303	0.847244623915173
GO:0004843	cysteine-type deubiquitinase activity	3/665	108/18639	0.0277777777777778	0.778571428571429	0.745719109034464	0.851389379681307
GO:0031491	nucleosome binding	2/665	74/18639	0.027027027027027	0.757528957528958	0.746475881194932	0.851389379681307
GO:0005501	retinoid binding	1/665	38/18639	0.0263157894736842	0.737593984962406	0.748907324719668	0.851389379681307
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	1/665	38/18639	0.0263157894736842	0.737593984962406	0.748907324719668	0.851389379681307
GO:0019840	isoprenoid binding	1/665	38/18639	0.0263157894736842	0.737593984962406	0.748907324719668	0.851389379681307
GO:0042162	telomeric DNA binding	1/665	38/18639	0.0263157894736842	0.737593984962406	0.748907324719668	0.851389379681307
GO:0004620	phospholipase activity	3/665	109/18639	0.0275229357798165	0.771428571428571	0.751306945656974	0.853119569133854
GO:0044183	protein folding chaperone	2/665	75/18639	0.0266666666666667	0.747428571428571	0.753124815816138	0.854185905453076
GO:0051536	iron-sulfur cluster binding	2/665	76/18639	0.0263157894736842	0.737593984962406	0.75962293000916	0.860366333366894
GO:1902936	phosphatidylinositol bisphosphate binding	3/665	111/18639	0.027027027027027	0.757528957528958	0.762186694884966	0.860366333366894
GO:0051540	metal cluster binding	2/665	77/18639	0.025974025974026	0.728014842300557	0.765972503209029	0.860366333366894
GO:0004177	aminopeptidase activity	1/665	40/18639	0.025	0.700714285714286	0.766540375201369	0.860366333366894
GO:0004532	RNA exonuclease activity	1/665	40/18639	0.025	0.700714285714286	0.766540375201369	0.860366333366894
GO:0015036	disulfide oxidoreductase activity	1/665	40/18639	0.025	0.700714285714286	0.766540375201369	0.860366333366894
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	1/665	40/18639	0.025	0.700714285714286	0.766540375201369	0.860366333366894
GO:0050997	quaternary ammonium group binding	1/665	40/18639	0.025	0.700714285714286	0.766540375201369	0.860366333366894
GO:0140662	ATP-dependent protein folding chaperone	1/665	40/18639	0.025	0.700714285714286	0.766540375201369	0.860366333366894
GO:0046982	protein heterodimerization activity	11/665	369/18639	0.029810298102981	0.835540069686411	0.769582513112059	0.862784547571997
GO:0001530	lipopolysaccharide binding	1/665	41/18639	0.024390243902439	0.683623693379791	0.774887633144865	0.865736528065297
GO:0016877	ligase activity, forming carbon-sulfur bonds	1/665	41/18639	0.024390243902439	0.683623693379791	0.774887633144865	0.865736528065297
GO:0140828	metal cation:monoatomic cation antiporter activity	1/665	41/18639	0.024390243902439	0.683623693379791	0.774887633144865	0.865736528065297
GO:0033293	monocarboxylic acid binding	2/665	79/18639	0.0253164556962025	0.709584086799277	0.778235286997211	0.868478414421687
GO:0101005	deubiquitinase activity	3/665	115/18639	0.0260869565217391	0.731180124223602	0.782786752013499	0.868738171831804
GO:0004402	histone acetyltransferase activity	1/665	42/18639	0.0238095238095238	0.66734693877551	0.782936870910144	0.868738171831804
GO:0042056	chemoattractant activity	1/665	42/18639	0.0238095238095238	0.66734693877551	0.782936870910144	0.868738171831804
GO:0043175	RNA polymerase core enzyme binding	1/665	42/18639	0.0238095238095238	0.66734693877551	0.782936870910144	0.868738171831804
GO:0051879	Hsp90 protein binding	1/665	42/18639	0.0238095238095238	0.66734693877551	0.782936870910144	0.868738171831804
GO:0008237	metallopeptidase activity	5/665	184/18639	0.0271739130434783	0.761645962732919	0.789919850384215	0.874356256221749
GO:0008200	ion channel inhibitor activity	1/665	43/18639	0.0232558139534884	0.651827242524917	0.790698713188186	0.874356256221749
GO:0048156	tau protein binding	1/665	43/18639	0.0232558139534884	0.651827242524917	0.790698713188186	0.874356256221749
GO:0019208	phosphatase regulator activity	3/665	117/18639	0.0256410256410256	0.718681318681319	0.792522014769731	0.875376589041112
GO:0015276	ligand-gated monoatomic ion channel activity	5/665	186/18639	0.0268817204301075	0.753456221198157	0.797601390701605	0.877640578122941
GO:0001223	transcription coactivator binding	1/665	44/18639	0.0227272727272727	0.637012987012987	0.798183406441029	0.877640578122941
GO:0016248	channel inhibitor activity	1/665	44/18639	0.0227272727272727	0.637012987012987	0.798183406441029	0.877640578122941
GO:0030020	extracellular matrix structural constituent conferring tensile strength	1/665	44/18639	0.0227272727272727	0.637012987012987	0.798183406441029	0.877640578122941
GO:0001540	amyloid-beta binding	2/665	83/18639	0.0240963855421687	0.675387263339071	0.801081346474438	0.877847879112913
GO:0005254	chloride channel activity	2/665	83/18639	0.0240963855421687	0.675387263339071	0.801081346474438	0.877847879112913
GO:0008135	translation factor activity, RNA binding	2/665	83/18639	0.0240963855421687	0.675387263339071	0.801081346474438	0.877847879112913
GO:0022834	ligand-gated channel activity	5/665	188/18639	0.0265957446808511	0.745440729483283	0.805060663370911	0.878619089832808
GO:0004715	non-membrane spanning protein tyrosine kinase activity	1/665	45/18639	0.0222222222222222	0.622857142857143	0.805400832346741	0.878619089832808
GO:0008009	chemokine activity	1/665	45/18639	0.0222222222222222	0.622857142857143	0.805400832346741	0.878619089832808
GO:0141110	transporter inhibitor activity	1/665	45/18639	0.0222222222222222	0.622857142857143	0.805400832346741	0.878619089832808
GO:0180051	translation factor activity	2/665	84/18639	0.0238095238095238	0.66734693877551	0.806456846004985	0.878784814256553
GO:0004180	carboxypeptidase activity	1/665	46/18639	0.0217391304347826	0.609316770186335	0.812360520767168	0.883237613183095
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	1/665	46/18639	0.0217391304347826	0.609316770186335	0.812360520767168	0.883237613183095
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	3/665	122/18639	0.0245901639344262	0.689227166276347	0.815278011938077	0.885419248719342
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	2/665	86/18639	0.0232558139534884	0.651827242524917	0.81682136200597	0.885581374540827
GO:0061733	protein-lysine-acetyltransferase activity	1/665	47/18639	0.0212765957446809	0.596352583586626	0.819071662255353	0.885581374540827
GO:0099095	ligand-gated monoatomic anion channel activity	1/665	47/18639	0.0212765957446809	0.596352583586626	0.819071662255353	0.885581374540827
GO:0140359	ABC-type transporter activity	1/665	47/18639	0.0212765957446809	0.596352583586626	0.819071662255353	0.885581374540827
GO:0008188	neuropeptide receptor activity	1/665	48/18639	0.0208333333333333	0.583928571428571	0.825543120118961	0.890597017486826
GO:0032266	phosphatidylinositol-3-phosphate binding	1/665	48/18639	0.0208333333333333	0.583928571428571	0.825543120118961	0.890597017486826
GO:0003727	single-stranded RNA binding	2/665	89/18639	0.0224719101123595	0.629855537720706	0.831437683233488	0.89596167195449
GO:0008083	growth factor activity	4/665	162/18639	0.0246913580246914	0.692063492063492	0.834223458201486	0.8979681078315
GO:0019783	ubiquitin-like protein peptidase activity	3/665	127/18639	0.0236220472440945	0.662092238470191	0.835882257269673	0.898758356267834
GO:0048020	CCR chemokine receptor binding	1/665	50/18639	0.02	0.560571428571429	0.837800871374049	0.899825908260305
GO:0003924	GTPase activity	9/665	331/18639	0.027190332326284	0.762106171773845	0.839243890164019	0.900380862295173
GO:0015081	sodium ion transmembrane transporter activity	4/665	164/18639	0.024390243902439	0.683623693379791	0.841151352946877	0.901079630550161
GO:0003743	translation initiation factor activity	1/665	51/18639	0.0196078431372549	0.549579831932773	0.843603357819595	0.901079630550161
GO:0005048	signal sequence binding	1/665	51/18639	0.0196078431372549	0.549579831932773	0.843603357819595	0.901079630550161
GO:0030544	Hsp70 protein binding	1/665	51/18639	0.0196078431372549	0.549579831932773	0.843603357819595	0.901079630550161
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	3/665	130/18639	0.0230769230769231	0.646813186813187	0.847270602250426	0.904003320952156
GO:0031072	heat shock protein binding	3/665	131/18639	0.0229007633587786	0.641875681570338	0.850911261414363	0.904864124661092
GO:0016410	N-acyltransferase activity	2/665	94/18639	0.0212765957446809	0.596352583586626	0.853473964898045	0.904864124661092
GO:0005201	extracellular matrix structural constituent	4/665	168/18639	0.0238095238095238	0.66734693877551	0.854279094118786	0.904864124661092
GO:0005179	hormone activity	3/665	132/18639	0.0227272727272727	0.637012987012987	0.854476125738942	0.904864124661092
GO:0016860	intramolecular oxidoreductase activity	1/665	53/18639	0.0188679245283019	0.528840970350404	0.854593895513254	0.904864124661092
GO:0034212	protein N-acetyltransferase activity	1/665	53/18639	0.0188679245283019	0.528840970350404	0.854593895513254	0.904864124661092
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	1/665	53/18639	0.0188679245283019	0.528840970350404	0.854593895513254	0.904864124661092
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	1/665	54/18639	0.0185185185185185	0.519047619047619	0.859796470541968	0.909382121182582
GO:0004896	cytokine receptor activity	2/665	96/18639	0.0208333333333333	0.583928571428571	0.861528794868931	0.910223900665871
GO:0030594	neurotransmitter receptor activity	2/665	97/18639	0.0206185567010309	0.577908689248895	0.86540241819947	0.913323724744718
GO:0016779	nucleotidyltransferase activity	3/665	136/18639	0.0220588235294118	0.61827731092437	0.868000841104875	0.914081059105026
GO:0099094	ligand-gated monoatomic cation channel activity	3/665	136/18639	0.0220588235294118	0.61827731092437	0.868000841104875	0.914081059105026
GO:0004601	peroxidase activity	1/665	57/18639	0.0175438596491228	0.491729323308271	0.874315227158731	0.919734199998145
GO:0140101	catalytic activity, acting on a tRNA	3/665	139/18639	0.0215827338129496	0.604933196300103	0.877405261947648	0.921986934716879
GO:0008408	3'-5' exonuclease activity	1/665	58/18639	0.0172413793103448	0.483251231527094	0.878813148477181	0.922469093217948
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	1/665	59/18639	0.0169491525423729	0.475060532687651	0.883150334649221	0.924028121936537
GO:0036002	pre-mRNA binding	1/665	59/18639	0.0169491525423729	0.475060532687651	0.883150334649221	0.924028121936537
GO:0070063	RNA polymerase binding	1/665	59/18639	0.0169491525423729	0.475060532687651	0.883150334649221	0.924028121936537
GO:0005253	monoatomic anion channel activity	2/665	103/18639	0.0194174757281553	0.544244105409154	0.886627277762879	0.924423591293411
GO:0001098	basal transcription machinery binding	1/665	60/18639	0.0166666666666667	0.467142857142857	0.887332521272379	0.924423591293411
GO:0001099	basal RNA polymerase II transcription machinery binding	1/665	60/18639	0.0166666666666667	0.467142857142857	0.887332521272379	0.924423591293411
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/665	60/18639	0.0166666666666667	0.467142857142857	0.887332521272379	0.924423591293411
GO:0016836	hydro-lyase activity	1/665	61/18639	0.0163934426229508	0.459484777517564	0.89136523957551	0.927630634761665
GO:0022824	transmitter-gated monoatomic ion channel activity	1/665	63/18639	0.0158730158730159	0.444897959183673	0.899003417663694	0.933580472189221
GO:0022835	transmitter-gated channel activity	1/665	63/18639	0.0158730158730159	0.444897959183673	0.899003417663694	0.933580472189221
GO:0160215	deacylase activity	1/665	65/18639	0.0153846153846154	0.431208791208791	0.906105301298192	0.939951283737292
GO:0008235	metalloexopeptidase activity	1/665	66/18639	0.0151515151515152	0.424675324675325	0.909466988314273	0.942432742688138
GO:0008173	RNA methyltransferase activity	1/665	67/18639	0.0149253731343284	0.418336886993603	0.912708492259301	0.943779419655363
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	1/665	67/18639	0.0149253731343284	0.418336886993603	0.912708492259301	0.943779419655363
GO:0008080	N-acetyltransferase activity	1/665	69/18639	0.0144927536231884	0.406211180124224	0.918847959610777	0.949118189948645
GO:0140375	immune receptor activity	3/665	156/18639	0.0192307692307692	0.539010989010989	0.920253925109141	0.949561374953381
GO:0015294	solute:monoatomic cation symporter activity	2/665	116/18639	0.0172413793103448	0.483251231527094	0.92240127247041	0.950767801528355
GO:0042379	chemokine receptor binding	1/665	72/18639	0.0138888888888889	0.389285714285714	0.927258190122774	0.954761611016246
GO:0004521	RNA endonuclease activity	1/665	73/18639	0.0136986301369863	0.383953033268102	0.929863527741579	0.955420030618198
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	1/665	73/18639	0.0136986301369863	0.383953033268102	0.929863527741579	0.955420030618198
GO:0004540	RNA nuclease activity	2/665	121/18639	0.0165289256198347	0.463282172373081	0.933089642143021	0.95671216472892
GO:0051082	unfolded protein binding	2/665	121/18639	0.0165289256198347	0.463282172373081	0.933089642143021	0.95671216472892
GO:0140098	catalytic activity, acting on RNA	9/665	387/18639	0.0232558139534884	0.651827242524917	0.937210367854721	0.959924633882812
GO:0015370	solute:sodium symporter activity	1/665	79/18639	0.0126582278481013	0.354792043399638	0.943651214608654	0.964488938590549
GO:0016835	carbon-oxygen lyase activity	1/665	79/18639	0.0126582278481013	0.354792043399638	0.943651214608654	0.964488938590549
GO:0042277	peptide binding	5/665	249/18639	0.0200803212851406	0.562822719449225	0.94526325164667	0.964589394533649
GO:0031490	chromatin DNA binding	2/665	128/18639	0.015625	0.437946428571429	0.945734252047909	0.964589394533649
GO:0004527	exonuclease activity	1/665	84/18639	0.0119047619047619	0.333673469387755	0.953049035699518	0.971031092976868
GO:0016209	antioxidant activity	1/665	86/18639	0.0116279069767442	0.325913621262458	0.956354204836569	0.973378311100676
GO:0016853	isomerase activity	3/665	180/18639	0.0166666666666667	0.467142857142857	0.957746834151415	0.97377606986943
GO:0070851	growth factor receptor binding	2/665	139/18639	0.0143884892086331	0.403288797533402	0.961119683573608	0.976184255416454
GO:0016407	acetyltransferase activity	1/665	96/18639	0.0104166666666667	0.291964285714286	0.969704393390296	0.983875438805186
GO:0008168	methyltransferase activity	3/665	204/18639	0.0147058823529412	0.41218487394958	0.978206688982902	0.991467050773077
GO:0043022	ribosome binding	1/665	112/18639	0.00892857142857143	0.250255102040816	0.983115118925005	0.994261657316153
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	2/665	167/18639	0.0119760479041916	0.335671514114628	0.983685017255402	0.994261657316153
GO:0016741	transferase activity, transferring one-carbon groups	3/665	215/18639	0.013953488372093	0.39109634551495	0.984032627919896	0.994261657316153
GO:0008528	G protein-coupled peptide receptor activity	1/665	122/18639	0.00819672131147541	0.229742388758782	0.988285910022396	0.995883440405212
GO:0005126	cytokine receptor binding	4/665	275/18639	0.0145454545454545	0.407688311688312	0.989573216781581	0.995883440405212
GO:0004519	endonuclease activity	1/665	127/18639	0.0078740157480315	0.220697412823397	0.99024379144688	0.995883440405212
GO:0001653	peptide receptor activity	1/665	128/18639	0.0078125	0.218973214285714	0.990594260261045	0.995883440405212
GO:0005125	cytokine activity	3/665	234/18639	0.0128205128205128	0.359340659340659	0.990760583201482	0.995883440405212
GO:0004518	nuclease activity	2/665	209/18639	0.00956937799043062	0.268215994531784	0.995742405516928	0.999177129816918
GO:0046906	tetrapyrrole binding	1/665	152/18639	0.00657894736842105	0.184398496240602	0.996093249786618	0.999177129816918
GO:0003823	antigen binding	1/665	174/18639	0.00574712643678161	0.161083743842365	0.99825581335476	0.999994219002343
GO:0045182	translation regulator activity	2/665	356/18639	0.00561797752808989	0.157463884430177	0.999969284741791	0.999994219002343
GO:0030371	translation repressor activity	1/665	329/18639	0.00303951367781155	0.0851932262266609	0.999994219002343	0.999994219002343