category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 5/24 238/9376 8.20728291316527 CFD/RPL7A/RPS3/RPL3/RPL18 5.7052342634028 Genetic Information Processing Translation hsa03010 Ribosome 4/24 222/9376 7.03903903903904 RPL7A/RPS3/RPL3/RPL18 4.61294079051002 Metabolism Energy metabolism hsa00910 Nitrogen metabolism 1/24 17/9376 22.9803921568627 GLUL 4.59498590489124 Cellular Processes Cell growth and death hsa04210 Apoptosis 2/24 137/9376 5.70316301703163 CTSH/GADD45G 2.80916236962856 Metabolism Amino acid metabolism hsa00220 Arginine biosynthesis 1/24 23/9376 16.9855072463768 GLUL 3.88824733063306 Metabolism Metabolism of cofactors and vitamins hsa00790 Folate biosynthesis 1/24 28/9376 13.952380952381 DHFR 3.47702876124545 Human Diseases Cancer: specific types hsa05225 Hepatocellular carcinoma 2/24 170/9376 4.59607843137255 MGST1/GADD45G 2.39693987680221 Human Diseases Drug resistance: antineoplastic hsa01523 Antifolate resistance 1/24 30/9376 13.0222222222222 DHFR 3.34096172545516 Metabolism Carbohydrate metabolism hsa00630 Glyoxylate and dicarboxylate metabolism 1/24 31/9376 12.6021505376344 GLUL 3.2776962191932 NA NA hsa04981 Folate transport and metabolism 1/24 31/9376 12.6021505376344 DHFR 3.2776962191932 Human Diseases Immune disease hsa05310 Asthma 1/24 32/9376 12.2083333333333 PRG2 3.21727824676002 Metabolism Glycan biosynthesis and metabolism hsa00512 Mucin type O-glycan biosynthesis 1/24 36/9376 10.8518518518519 GALNT15 3.00009284166616 Metabolism Amino acid metabolism hsa00250 Alanine, aspartate and glutamate metabolism 1/24 37/9376 10.5585585585586 GLUL 2.95108751947491 Human Diseases Cancer: specific types hsa05216 Thyroid cancer 1/24 37/9376 10.5585585585586 GADD45G 2.95108751947491 Human Diseases Cancer: overview hsa05205 Proteoglycans in cancer 2/24 204/9376 3.83006535947712 LUM/DCN 2.07022970674073 Metabolism Metabolism of cofactors and vitamins hsa00670 One carbon pool by folate 1/24 39/9376 10.017094017094 DHFR 2.85847390553209 NA NA hsa03272 Virion - Hepatitis viruses 1/24 48/9376 8.13888888888889 CD81 2.51186319520471 Metabolism Glycan biosynthesis and metabolism hsa00514 Other types of O-glycan biosynthesis 1/24 49/9376 7.97278911564626 GALNT15 2.4789775414771 Human Diseases Infectious disease: parasitic hsa05144 Malaria 1/24 50/9376 7.81333333333333 CD81 2.44701112226212 Human Diseases Infectious disease: bacterial hsa05134 Legionellosis 1/24 56/9376 6.97619047619048 EEF1A1 2.27221539702431 Metabolism Metabolism of other amino acids hsa00480 Glutathione metabolism 1/24 59/9376 6.62146892655367 MGST1 2.19420288850928 Human Diseases Cancer: specific types hsa05213 Endometrial cancer 1/24 59/9376 6.62146892655367 GADD45G 2.19420288850928 Metabolism Lipid metabolism hsa00590 Arachidonic acid metabolism 1/24 63/9376 6.2010582010582 PTGDS 2.09824499999998 Human Diseases Cancer: specific types hsa05217 Basal cell carcinoma 1/24 63/9376 6.2010582010582 GADD45G 2.09824499999998 Human Diseases Cancer: overview hsa05204 Chemical carcinogenesis - DNA adducts 1/24 70/9376 5.58095238095238 MGST1 1.9487776186565 Metabolism Xenobiotics biodegradation and metabolism hsa00982 Drug metabolism - cytochrome P450 1/24 73/9376 5.35159817351598 MGST1 1.89076570045791 Human Diseases Cancer: specific types hsa05218 Melanoma 1/24 73/9376 5.35159817351598 GADD45G 1.89076570045791 Human Diseases Cancer: specific types hsa05223 Non-small cell lung cancer 1/24 73/9376 5.35159817351598 GADD45G 1.89076570045791 Metabolism Global and overview maps hsa01230 Biosynthesis of amino acids 1/24 75/9376 5.20888888888889 GLUL 1.85384013554985 Human Diseases Drug resistance: antineoplastic hsa01524 Platinum drug resistance 1/24 75/9376 5.20888888888889 MGST1 1.85384013554985 Cellular Processes Cell growth and death hsa04115 p53 signaling pathway 1/24 75/9376 5.20888888888889 GADD45G 1.85384013554985 Human Diseases Cancer: specific types hsa05214 Glioma 1/24 76/9376 5.14035087719298 GADD45G 1.83586811491068 Human Diseases Cancer: specific types hsa05212 Pancreatic cancer 1/24 77/9376 5.07359307359307 GADD45G 1.81820937295977 Human Diseases Cancer: specific types hsa05220 Chronic myeloid leukemia 1/24 77/9376 5.07359307359307 GADD45G 1.81820937295977 Human Diseases Infectious disease: parasitic hsa05140 Leishmaniasis 1/24 78/9376 5.00854700854701 EEF1A1 1.80085406852609 Metabolism Xenobiotics biodegradation and metabolism hsa00980 Metabolism of xenobiotics by cytochrome P450 1/24 79/9376 4.94514767932489 MGST1 1.78379279333144 Metabolism Xenobiotics biodegradation and metabolism hsa00983 Drug metabolism - other enzymes 1/24 82/9376 4.76422764227642 MGST1 1.73428505519617 Human Diseases Cancer: specific types hsa05210 Colorectal cancer 1/24 87/9376 4.4904214559387 GADD45G 1.65688369617594 Organismal Systems Immune system hsa04610 Complement and coagulation cascades 1/24 88/9376 4.43939393939394 CFD 1.6421059107609 Organismal Systems Nervous system hsa04727 GABAergic synapse 1/24 89/9376 4.38951310861423 GLUL 1.62754726034769 Organismal Systems Immune system hsa04662 B cell receptor signaling pathway 1/24 91/9376 4.29304029304029 CD81 1.59906381867021 Organismal Systems Digestive system hsa04970 Salivary secretion 1/24 93/9376 4.20071684587814 CST3 1.57138847883527 Human Diseases Cancer: specific types hsa05222 Small cell lung cancer 1/24 93/9376 4.20071684587814 GADD45G 1.57138847883527 Human Diseases Infectious disease: bacterial hsa05150 Staphylococcus aureus infection 1/24 99/9376 3.94612794612795 CFD 1.49280964605985 Environmental Information Processing Signal transduction hsa04064 NF-kappa B signaling pathway 1/24 105/9376 3.72063492063492 GADD45G 1.42017099029537 Genetic Information Processing Translation hsa03013 Nucleocytoplasmic transport 1/24 108/9376 3.61728395061728 EEF1A1 1.38582603886085 Environmental Information Processing Signal transduction hsa04350 TGF-beta signaling pathway 1/24 110/9376 3.55151515151515 DCN 1.36360114191379 Organismal Systems Endocrine system hsa04928 Parathyroid hormone synthesis, secretion and action 1/24 115/9376 3.39710144927536 NACA 1.31022355405774 Organismal Systems Nervous system hsa04724 Glutamatergic synapse 1/24 116/9376 3.36781609195402 GLUL 1.29990160206737 Environmental Information Processing Signal transduction hsa04068 FoxO signaling pathway 1/24 133/9376 2.93734335839599 GADD45G 1.13989527162798 Organismal Systems Circulatory system hsa04270 Vascular smooth muscle contraction 1/24 134/9376 2.91542288557214 RAMP1 1.13128778831153 Human Diseases Cardiovascular disease hsa05418 Fluid shear stress and atherosclerosis 1/24 142/9376 2.75117370892019 MGST1 1.0651664416809 Human Diseases Cancer: specific types hsa05224 Breast cancer 1/24 148/9376 2.63963963963964 GADD45G 1.0185080923531 Human Diseases Cancer: specific types hsa05226 Gastric cancer 1/24 150/9376 2.60444444444444 GADD45G 1.00346585235987 Metabolism Global and overview maps hsa01240 Biosynthesis of cofactors 1/24 154/9376 2.53679653679654 DHFR 0.974099195393406 Human Diseases Infectious disease: viral hsa05160 Hepatitis C 1/24 156/9376 2.5042735042735 CD81 0.959760019562438 Cellular Processes Cell growth and death hsa04218 Cellular senescence 1/24 157/9376 2.48832271762208 GADD45G 0.952673400586972 Cellular Processes Cell growth and death hsa04110 Cell cycle 1/24 158/9376 2.47257383966245 GADD45G 0.945640975899488 Cellular Processes Cell growth and death hsa04217 Necroptosis 1/24 168/9376 2.32539682539683 GLUL 0.878126172687019 Environmental Information Processing Signal transduction hsa04310 Wnt signaling pathway 1/24 178/9376 2.19475655430712 DKK1 0.815232960483528 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 1/24 180/9376 2.17037037037037 PILRA 0.803154504951497 Organismal Systems Immune system hsa04621 NOD-like receptor signaling pathway 1/24 187/9376 2.08912655971479 TXNIP 0.762086093061749 NA NA hsa04082 Neuroactive ligand signaling 1/24 199/9376 1.96314907872697 P2RY14 0.695678682984507 Human Diseases Infectious disease: bacterial hsa05130 Pathogenic Escherichia coli infection 1/24 200/9376 1.95333333333333 RPS3 0.690354378676375 Human Diseases Cancer: overview hsa05202 Transcriptional misregulation in cancer 1/24 201/9376 1.94361525704809 GADD45G 0.685060546198247 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 1/24 205/9376 1.90569105691057 GADD45G 0.664182874134183 Human Diseases Cancer: overview hsa05207 Chemical carcinogenesis - receptor activation 1/24 217/9376 1.80030721966206 MGST1 0.604229023238884 NA NA hsa04081 Hormone signaling 1/24 219/9376 1.78386605783866 RAMP1 0.594601937191509 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 1/24 227/9376 1.72099853157122 MGST1 0.557056832003947 Cellular Processes Cell motility hsa04820 Cytoskeleton in muscle cells 1/24 233/9376 1.67668097281831 DCN 0.529854437161239 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 1/24 248/9376 1.5752688172043 RPS3 0.465101637075652 Cellular Processes Transport and catabolism hsa04142 Lysosome biogenesis 1/24 250/9376 1.56266666666667 CTSH 0.456793557041669 Environmental Information Processing Signal transduction hsa04010 MAPK signaling pathway 1/24 300/9376 1.30222222222222 GADD45G 0.269512422888904 Environmental Information Processing Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction 1/24 370/9376 1.05585585585586 P2RY14 0.0555319100356782 Human Diseases Neurodegenerative disease hsa05010 Alzheimer disease 1/24 388/9376 1.00687285223368 DKK1 0.00700422917549315 Human Diseases Neurodegenerative disease hsa05022 Pathways of neurodegeneration - multiple diseases 1/24 480/9376 0.813888888888889 DKK1 -0.212048177167819