category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 8/35 238/9376 9.00456182472989 CFD/RPL14/RPL9/C7/RPL39/RPS27/RPS3/RPL7A 7.65637928077382 Genetic Information Processing Translation hsa03010 Ribosome 6/35 222/9376 7.24015444015444 RPL14/RPL9/RPL39/RPS27/RPS3/RPL7A 5.75956051695286 Organismal Systems Immune system hsa04610 Complement and coagulation cascades 4/35 88/9376 12.1766233766234 CFD/SERPINE2/C7/CLU 6.44783363809974 Cellular Processes Cell growth and death hsa04216 Ferroptosis 3/35 42/9376 19.134693877551 FTL/SLC40A1/FTH1 7.20981216182171 Organismal Systems Digestive system hsa04978 Mineral absorption 3/35 61/9376 13.1747072599532 FTL/SLC40A1/FTH1 5.83922203697023 Cellular Processes Cellular community - eukaryotes hsa04540 Gap junction 3/35 89/9376 9.02985553772071 GJA1/PDGFRA/TUBA4A 4.658949328277 Metabolism Metabolism of cofactors and vitamins hsa00860 Porphyrin metabolism 2/35 46/9376 11.6472049689441 FTL/FTH1 4.43094830300222 Cellular Processes Transport and catabolism hsa04145 Phagosome 3/35 155/9376 5.18488479262673 CD36/CORO1A/TUBA4A 3.21575770610364 Cellular Processes Cell growth and death hsa04217 Necroptosis 3/35 168/9376 4.78367346938775 FTL/FTH1/GLUL 3.02906511724652 Organismal Systems Nervous system hsa04727 GABAergic synapse 2/35 89/9376 6.0199036918138 GNGT1/GLUL 2.91256509200286 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 3/35 214/9376 3.75540720961282 GNGT1/BST2/CD247 2.49586164848877 Organismal Systems Immune system hsa04658 Th1 and Th2 cell differentiation 2/35 93/9376 5.76098310291859 CD247/RUNX3 2.82433958839326 Metabolism Energy metabolism hsa00910 Nitrogen metabolism 1/35 17/9376 15.7579831932773 GLUL 3.72786110539011 Organismal Systems Nervous system hsa04724 Glutamatergic synapse 2/35 116/9376 4.61871921182266 GNGT1/GLUL 2.40049807315682 Metabolism Amino acid metabolism hsa00220 Arginine biosynthesis 1/35 23/9376 11.6472049689441 GLUL 3.12929884556173 Metabolism Metabolism of cofactors and vitamins hsa00790 Folate biosynthesis 1/35 28/9376 9.56734693877551 DHFR 2.77900285125923 Organismal Systems Sensory system hsa04744 Phototransduction 1/35 29/9376 9.23743842364532 GNGT1 2.71943093216596 Human Diseases Drug resistance: antineoplastic hsa01523 Antifolate resistance 1/35 30/9376 8.92952380952381 DHFR 2.66267291634241 Metabolism Carbohydrate metabolism hsa00630 Glyoxylate and dicarboxylate metabolism 1/35 31/9376 8.64147465437788 GLUL 2.60850302895721 NA NA hsa04981 Folate transport and metabolism 1/35 31/9376 8.64147465437788 DHFR 2.60850302895721 Human Diseases Immune disease hsa05310 Asthma 1/35 32/9376 8.37142857142857 PRG2 2.5567202442607 Cellular Processes Transport and catabolism hsa04148 Efferocytosis 2/35 157/9376 3.41255686988171 CD36/BSG 1.86598630741393 Metabolism Amino acid metabolism hsa00250 Alanine, aspartate and glutamate metabolism 1/35 37/9376 7.24015444015444 GLUL 2.32792501452455 Metabolism Metabolism of cofactors and vitamins hsa00670 One carbon pool by folate 1/35 39/9376 6.86886446886447 DHFR 2.24804851149808 Organismal Systems Digestive system hsa04975 Fat digestion and absorption 1/35 43/9376 6.22990033222591 CD36 2.10397212507872 Human Diseases Infectious disease: parasitic hsa05144 Malaria 1/35 50/9376 5.35771428571429 CD36 1.89111971937103 Human Diseases Infectious disease: bacterial hsa05130 Pathogenic Escherichia coli infection 2/35 200/9376 2.67885714285714 RPS3/TUBA4A 1.46901088051422 Human Diseases Cancer: overview hsa05202 Transcriptional misregulation in cancer 2/35 201/9376 2.66552949538024 IGFBP3/NUPR1 1.46106754818901 Organismal Systems Digestive system hsa04979 Cholesterol metabolism 1/35 52/9376 5.15164835164835 CD36 1.83757077430382 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 2/35 205/9376 2.61351916376307 CD247/RUNX3 1.42976837280865 NA NA hsa04081 Hormone signaling 2/35 219/9376 2.44644487932159 GNGT1/SLC40A1 1.32577648876726 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 2/35 227/9376 2.36022655758339 GNGT1/PDGFRA 1.26987314538866 Metabolism Lipid metabolism hsa00590 Arachidonic acid metabolism 1/35 63/9376 4.25215419501134 PTGDS 1.58532962841957 Cellular Processes Cell motility hsa04810 Regulation of actin cytoskeleton 2/35 232/9376 2.30935960591133 C7/PDGFRA 1.23611192675274 Environmental Information Processing Signal transduction hsa04014 Ras signaling pathway 2/35 238/9376 2.25114045618247 GNGT1/PDGFRA 1.19671833084713 Organismal Systems Endocrine system hsa04924 Renin secretion 1/35 69/9376 3.8824016563147 KCNMA1 1.47094746254932 Organismal Systems Endocrine system hsa04920 Adipocytokine signaling pathway 1/35 70/9376 3.8269387755102 CD36 1.45313804429665 Human Diseases Cancer: overview hsa05230 Central carbon metabolism in cancer 1/35 71/9376 3.77303822937626 PDGFRA 1.43565410411096 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 2/35 248/9376 2.16036866359447 RPS3/TUBA4A 1.13359257065319 Genetic Information Processing Information processing in viruses hsa03250 Viral life cycle - HIV-1 1/35 73/9376 3.66966731898239 BST2 1.40161920308092 Human Diseases Cancer: specific types hsa05218 Melanoma 1/35 73/9376 3.66966731898239 PDGFRA 1.40161920308092 Metabolism Global and overview maps hsa01230 Biosynthesis of amino acids 1/35 75/9376 3.57180952380952 GLUL 1.36876087928979 Cellular Processes Cell growth and death hsa04115 p53 signaling pathway 1/35 75/9376 3.57180952380952 IGFBP3 1.36876087928979 Organismal Systems Endocrine system hsa03320 PPAR signaling pathway 1/35 76/9376 3.52481203007519 CD36 1.35274939083119 Human Diseases Cancer: specific types hsa05214 Glioma 1/35 76/9376 3.52481203007519 PDGFRA 1.35274939083119 Human Diseases Drug resistance: antineoplastic hsa01521 EGFR tyrosine kinase inhibitor resistance 1/35 80/9376 3.34857142857143 PDGFRA 1.2912896899416 Human Diseases Neurodegenerative disease hsa05020 Prion disease 2/35 275/9376 1.94825974025974 C7/TUBA4A 0.97694941329745 Organismal Systems Endocrine system hsa04911 Insulin secretion 1/35 86/9376 3.11495016611296 KCNMA1 1.20604769130185 Human Diseases Cardiovascular disease hsa05412 Arrhythmogenic right ventricular cardiomyopathy 1/35 86/9376 3.11495016611296 GJA1 1.20604769130185 Environmental Information Processing Signaling molecules and interaction hsa04512 ECM-receptor interaction 1/35 89/9376 3.0099518459069 CD36 1.16618085572871 Human Diseases Cancer: overview hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer 1/35 90/9376 2.97650793650794 CD247 1.15326324726148 Human Diseases Substance dependence hsa05032 Morphine addiction 1/35 91/9376 2.94379905808477 GNGT1 1.14052309463264 Organismal Systems Digestive system hsa04970 Salivary secretion 1/35 93/9376 2.88049155145929 KCNMA1 1.11555672843487 Organismal Systems Environmental adaptation hsa04713 Circadian entrainment 1/35 97/9376 2.76170839469809 GNGT1 1.06755996287487 NA NA hsa04517 IgSF CAM signaling 2/35 299/9376 1.79187768752986 CADM3/TUBA4A 0.851815438266668 Human Diseases Infectious disease: bacterial hsa05150 Staphylococcus aureus infection 1/35 99/9376 2.70591630591631 CFD 1.04446649679407 Human Diseases Cancer: overview hsa05231 Choline metabolism in cancer 1/35 99/9376 2.70591630591631 PDGFRA 1.04446649679407 Organismal Systems Immune system hsa04640 Hematopoietic cell lineage 1/35 100/9376 2.67885714285714 CD36 1.03313326943114 Organismal Systems Digestive system hsa04972 Pancreatic secretion 1/35 102/9376 2.62633053221289 KCNMA1 1.01087703365112 Organismal Systems Digestive system hsa04974 Protein digestion and absorption 1/35 103/9376 2.60083217753121 SLC15A1 0.999947645304765 Human Diseases Infectious disease: parasitic hsa05142 Chagas disease 1/35 103/9376 2.60083217753121 CD247 0.999947645304765 Human Diseases Cancer: specific types hsa05215 Prostate cancer 1/35 106/9376 2.52722371967655 PDGFRA 0.967918298922329 Organismal Systems Immune system hsa04659 Th17 cell differentiation 1/35 109/9376 2.45766710353866 CD247 0.936968508672762 Human Diseases Endocrine and metabolic disease hsa04931 Insulin resistance 1/35 109/9376 2.45766710353866 CD36 0.936968508672762 Organismal Systems Nervous system hsa04725 Cholinergic synapse 1/35 115/9376 2.32944099378882 GNGT1 0.878035385543954 Organismal Systems Nervous system hsa04726 Serotonergic synapse 1/35 115/9376 2.32944099378882 GNGT1 0.878035385543954 Environmental Information Processing Signal transduction hsa04152 AMPK signaling pathway 1/35 122/9376 2.19578454332553 CD36 0.813750142323961 Organismal Systems Immune system hsa04660 T cell receptor signaling pathway 1/35 122/9376 2.19578454332553 CD247 0.813750142323961 Organismal Systems Endocrine system hsa04935 Growth hormone synthesis, secretion and action 1/35 122/9376 2.19578454332553 IGFBP3 0.813750142323961 Organismal Systems Endocrine system hsa04926 Relaxin signaling pathway 1/35 130/9376 2.06065934065934 GNGT1 0.74540727466114 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 2/35 362/9376 1.48003157063931 GNGT1/PDGFRA 0.570148890669388 Organismal Systems Immune system hsa04650 Natural killer cell mediated cytotoxicity 1/35 133/9376 2.01417830290011 CD247 0.721035476407645 Organismal Systems Nervous system hsa04728 Dopaminergic synapse 1/35 133/9376 2.01417830290011 GNGT1 0.721035476407645 Organismal Systems Circulatory system hsa04270 Vascular smooth muscle contraction 1/35 134/9376 1.99914712153518 KCNMA1 0.713053035399498 Cellular Processes Cell growth and death hsa04210 Apoptosis 1/35 137/9376 1.95537017726799 TUBA4A 0.689512993490857 Environmental Information Processing Signal transduction hsa04371 Apelin signaling pathway 1/35 140/9376 1.9134693877551 GNGT1 0.666559661745999 Human Diseases Immune disease hsa05322 Systemic lupus erythematosus 1/35 143/9376 1.87332667332667 C7 0.644163777439994 Environmental Information Processing Signal transduction hsa04072 Phospholipase D signaling pathway 1/35 149/9376 1.79789069990412 PDGFRA 0.600937424376916 Organismal Systems Nervous system hsa04723 Retrograde endocannabinoid signaling 1/35 149/9376 1.79789069990412 GNGT1 0.600937424376916 Metabolism Global and overview maps hsa01240 Biosynthesis of cofactors 1/35 154/9376 1.73951762523191 DHFR 0.56639486193896 NA NA hsa04518 Integrin signaling 1/35 154/9376 1.73951762523191 PDGFRA 0.56639486193896 Human Diseases Infectious disease: viral hsa05160 Hepatitis C 1/35 156/9376 1.71721611721612 EIF3E 0.552929617504713 Cellular Processes Cell growth and death hsa04218 Cellular senescence 1/35 157/9376 1.70627843494086 IGFBP3 0.546269356496452 NA NA hsa04519 Cadherin signaling 2/35 404/9376 1.32616690240453 GJA1/PDGFRA 0.41021252223131 Cellular Processes Cell growth and death hsa04110 Cell cycle 1/35 158/9376 1.69547920433996 CDKN1C 0.539656378400634 Environmental Information Processing Signaling molecules and interaction hsa04514 Cell adhesion molecule (CAM) interaction 1/35 160/9376 1.67428571428571 CADM3 0.526569489068411 Environmental Information Processing Signal transduction hsa04022 cGMP-PKG signaling pathway 1/35 166/9376 1.61376936316695 KCNMA1 0.488373859140344 Environmental Information Processing Signal transduction hsa04630 JAK-STAT signaling pathway 1/35 168/9376 1.59455782312925 PDGFRA 0.475980386996307 Cellular Processes Cellular community - eukaryotes hsa04530 Tight junction 1/35 170/9376 1.57579831932773 TUBA4A 0.463748312866196 Environmental Information Processing Signal transduction hsa04310 Wnt signaling pathway 1/35 178/9376 1.50497592295345 RSPO2 0.416348442629387 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 1/35 180/9376 1.48825396825397 BST2 0.404860611997273 Human Diseases Infectious disease: bacterial hsa05152 Tuberculosis 1/35 181/9376 1.48003157063931 CORO1A 0.399168439221515 Human Diseases Substance dependence hsa05034 Alcoholism 1/35 191/9376 1.40254300673149 GNGT1 0.344042713081242 Organismal Systems Immune system hsa04062 Chemokine signaling pathway 1/35 193/9376 1.3880088823094 GNGT1 0.333388798770939 Cellular Processes Cell motility hsa04814 Motor proteins 1/35 194/9376 1.38085419734904 TUBA4A 0.328105825516041 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 1/35 196/9376 1.3667638483965 GNGT1 0.317626106123933 NA NA hsa04082 Neuroactive ligand signaling 1/35 199/9376 1.34615936826992 GNGT1 0.302117050623632 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 1/35 203/9376 1.31963406052076 PDGFRA 0.281817753419723 Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 1/35 205/9376 1.30675958188153 CD36 0.271825186883634 Environmental Information Processing Signal transduction hsa04015 Rap1 signaling pathway 1/35 212/9376 1.26361185983827 PDGFRA 0.237636588869779 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 1/35 216/9376 1.24021164021164 CD36 0.21862315718848 Cellular Processes Transport and catabolism hsa04144 Endocytosis 1/35 250/9376 1.07154285714286 PDGFRA 0.0701809150823222 Environmental Information Processing Signal transduction hsa04020 Calcium signaling pathway 1/35 254/9376 1.05466816647919 PDGFRA 0.0540666307914184 Human Diseases Neurodegenerative disease hsa05012 Parkinson disease 1/35 268/9376 0.999573560767591 TUBA4A -0.000433546828225704 Environmental Information Processing Signal transduction hsa04010 MAPK signaling pathway 1/35 300/9376 0.892952380952381 PDGFRA -0.11534887687438 Human Diseases Neurodegenerative disease hsa05016 Huntington disease 1/35 308/9376 0.869758812615955 TUBA4A -0.142262659675173 Human Diseases Cancer: overview hsa05206 MicroRNAs in cancer 1/35 323/9376 0.82936753648828 PDGFRA -0.191024748371216 Human Diseases Neurodegenerative disease hsa05014 Amyotrophic lateral sclerosis 1/35 368/9376 0.727950310559006 TUBA4A -0.325897425288998 Human Diseases Neurodegenerative disease hsa05010 Alzheimer disease 1/35 388/9376 0.690427098674521 TUBA4A -0.381215229805679 Human Diseases Neurodegenerative disease hsa05022 Pathways of neurodegeneration - multiple diseases 1/35 480/9376 0.558095238095238 TUBA4A -0.608379942359155