category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	8/48	95/9376	16.4491228070175	CXCL8/ATP6V0B/CXCL2/ATP6V0E1/ATP6V0C/HLA-DQB1/HLA-DRB5/IL1B	10.8562598527083
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	7/48	82/9376	16.6747967479675	HSPA1A/B2M/HSP90AA1/IFI30/HLA-DQB1/HLA-DRB5/HSPA1B	10.2263228248633
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	6/48	56/9376	20.9285714285714	HSPA1A/CXCL8/CXCL2/NFKBIA/HSPA1B/IL1B	10.729369777681
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	6/48	71/9376	16.5070422535211	CXCL8/ATP6V0B/CXCL2/ATP6V0E1/ATP6V0C/NFKBIA	9.40831704634023
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	8/48	216/9376	7.23456790123457	SOD2/HSPA1A/CXCL8/HSP90AA1/CXCL2/NFKBIA/HSPA1B/IL1B	6.64963008090554
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	5/48	94/9376	10.3900709219858	CXCL8/HSP90AA1/CXCL2/NFKBIA/IL1B	6.56332644149839
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	6/48	155/9376	7.56129032258065	ATP6V0B/TUBB4B/ATP6V0E1/ATP6V0C/HLA-DQB1/HLA-DRB5	5.90851144359711
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	5/48	105/9376	9.3015873015873	BCL2A1/CXCL8/CXCL2/NFKBIA/IL1B	6.13627036708607
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	5/48	109/9376	8.96024464831804	HSP90AA1/NFKBIA/HLA-DQB1/HLA-DRB5/IL1B	5.99628230286025
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	7/48	248/9376	5.51344086021505	CXCL8/HSP90AA1/TUBB4B/MYL12A/NFKBIA/ARPC3/IL1B	5.1672297164352
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	5/48	112/9376	8.72023809523809	HSPA1A/NFKBIA/HLA-DQB1/HLA-DRB5/HSPA1B	5.89593138478788
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	7/48	253/9376	5.40447957839262	UBB/UBC/CXCL8/MYL12A/NFKBIA/ARPC3/IL1B	5.0944583035293
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	6/48	196/9376	5.97959183673469	UBB/UBC/CXCL8/CXCL2/NFKBIA/GNG10	5.05373458404347
Human Diseases	Immune disease	hsa05310	Asthma	3/48	32/9376	18.3125	PRG2/HLA-DQB1/HLA-DRB5	7.03688330222453
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	4/48	78/9376	10.017094017094	NFKBIA/HLA-DQB1/HLA-DRB5/IL1B	5.73629022951291
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	3/48	44/9376	13.3181818181818	HLA-DQB1/HLA-DRB5/IL1B	5.87486067284138
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	3/48	45/9376	13.0222222222222	HLA-DQB1/HLA-DRB5/IL1B	5.79881030057891
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	4/48	100/9376	7.81333333333333	HLA-DQB1/HLA-DRB5/CD37/IL1B	4.9135033324916
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	5/48	173/9376	5.64547206165703	CXCL8/NFKBIA/HLA-DQB1/HLA-DRB5/IL1B	4.42384784445791
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	5/48	180/9376	5.42592592592593	B2M/NFKBIA/HLA-DQB1/HLA-DRB5/IL1B	4.30083618081403
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	3/48	51/9376	11.4901960784314	ATP6V0B/ATP6V0E1/ATP6V0C	5.38835576149128
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	5/48	181/9376	5.39594843462247	ATP6V0B/ATP6V0C/HLA-DQB1/HLA-DRB5/IL1B	4.28378827928994
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	4/48	109/9376	7.16819571865443	CXCL8/NFKBIA/SPP1/IL1B	4.64637011328049
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	5/48	187/9376	5.22281639928699	CXCL8/HSP90AA1/CXCL2/NFKBIA/IL1B	4.18408853072997
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	5/48	200/9376	4.88333333333333	CXCL8/TUBB4B/NFKBIA/ARPC3/IL1B	3.98203391145021
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	3/48	62/9376	9.45161290322581	SOD2/HSPA1A/HSPA1B	4.78938019102878
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	3/48	66/9376	8.87878787878788	HLA-DQB1/HLA-DRB5/IL1B	4.60753373367201
Human Diseases	Infectious disease: viral	hsa05162	Measles	4/48	136/9376	5.74509803921569	HSPA1A/NFKBIA/HSPA1B/IL1B	3.99844058181514
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	4/48	138/9376	5.66183574879227	CXCL8/NFKBIA/ARPC3/IL1B	3.95748721318788
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	5/48	227/9376	4.30249632892805	B2M/CXCL8/NFKBIA/GNG10/IL1B	3.61310386665611
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	4/48	144/9376	5.42592592592593	CXCL8/CXCL2/NFKBIA/IL1B	3.83927726773934
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	3/48	79/9376	7.41772151898734	ATP6V0B/ATP6V0E1/ATP6V0C	4.10898907338879
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	5/48	250/9376	3.90666666666667	PPT1/CD63/ATP6V0B/ATP6V0E1/ATP6V0C	3.3414655695263
Organismal Systems	Excretory system	hsa04966	Collecting duct acid secretion	2/48	28/9376	13.952380952381	ATP6V0E1/ATP6V0C	4.92358297498336
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	2/48	30/9376	13.0222222222222	DHFR/IL1B	4.73090773791297
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	4/48	168/9376	4.65079365079365	FTL/FTH1/HSP90AA1/IL1B	3.42508426253153
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	5/48	268/9376	3.64427860696517	DUSP1/UBB/UBC/TUBB4B/PSMB3	3.15046809367659
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	4/48	174/9376	4.4904214559387	HSPA1A/HSP90AA1/DNAJA1/HSPA1B	3.33367583905866
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	3/48	93/9376	6.3010752688172	NFKBIA/HLA-DQB1/HLA-DRB5	3.68530348589165
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	5/48	275/9376	3.55151515151515	HSPA1A/TUBB4B/PSMB3/HSPA1B/IL1B	3.08057601360621
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	2/48	37/9376	10.5585585585586	IDO2/IL1B	4.17883350017733
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	3/48	103/9376	5.68932038834951	CXCL8/NFKBIA/IL1B	3.4326567385849
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	3/48	103/9376	5.68932038834951	CXCL8/CXCL2/IL1B	3.4326567385849
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	4/48	193/9376	4.04835924006909	CXCL8/CXCL2/NFKBIA/GNG10	3.06947779879437
Human Diseases	Immune disease	hsa05330	Allograft rejection	2/48	39/9376	10.017094017094	HLA-DQB1/HLA-DRB5	4.04768968625695
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	5/48	300/9376	3.25555555555556	HSPA1A/DUSP1/EREG/HSPA1B/IL1B	2.84825520965847
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	2/48	42/9376	9.3015873015873	IDO2/CYP1B1	3.86779880172576
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	2/48	42/9376	9.3015873015873	FTL/FTH1	3.86779880172576
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	4/48	205/9376	3.81138211382114	B2M/NFKBIA/HLA-DQB1/HLA-DRB5	2.91944601895329
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	3/48	119/9376	4.92436974789916	CXCL2/NFKBIA/IL1B	3.09043957216929
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	2/48	46/9376	8.4927536231884	FTL/FTH1	3.65419344735915
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	2/48	50/9376	7.81333333333333	HLA-DQB1/HLA-DRB5	3.46504533855198
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	2/48	50/9376	7.81333333333333	CXCL8/IL1B	3.46504533855198
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	4/48	224/9376	3.48809523809524	B2M/NFKBIA/HLA-DQB1/HLA-DRB5	2.70361589876467
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	2/48	54/9376	7.23456790123457	HLA-DQB1/HLA-DRB5	3.29579869948528
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	3/48	138/9376	4.2463768115942	ATP6V0B/ATP6V0E1/ATP6V0C	2.75588746866555
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	3/48	139/9376	4.2158273381295	HSPA1A/HSP90AA1/HSPA1B	2.73997524676016
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	3/48	142/9376	4.12676056338028	UBB/UBC/UBE2S	2.69312090453635
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	3/48	142/9376	4.12676056338028	DUSP1/HSP90AA1/IL1B	2.69312090453635
Organismal Systems	Digestive system	hsa04978	Mineral absorption	2/48	61/9376	6.40437158469945	FTL/FTH1	3.03760065609968
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	3/48	154/9376	3.80519480519481	DHFR/IDO2/NAPRT	2.51780919724326
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	2/48	70/9376	5.58095238095238	SULT1A1/CYP1B1	2.7595308995399
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	2/48	70/9376	5.58095238095238	HLA-DQB1/HLA-DRB5	2.7595308995399
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	2/48	72/9376	5.42592592592593	CXCL8/NFKBIA	2.70425428576875
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	2/48	76/9376	5.14035087719298	UBC/PLIN2	2.59964746211973
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	2/48	78/9376	5.00854700854701	CXCL8/IL1B	2.55006646221948
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	2/48	83/9376	4.70682730923695	SOD2/DHRS4	2.43318662053054
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	2/48	83/9376	4.70682730923695	NFKBIA/IL1B	2.43318662053054
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	2/48	86/9376	4.54263565891473	EREG/NRG1	2.36744471775751
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	2/48	88/9376	4.43939393939394	PLAUR/SERPINB2	2.32527403726333
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	4/48	333/9376	2.34634634634635	ATP6V0B/ATP6V0E1/ATP6V0C/SPP1	1.79446352712219
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	2/48	99/9376	3.94612794612795	HLA-DQB1/HLA-DRB5	2.11386579258507
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	2/48	100/9376	3.90666666666667	CXCL8/CXCL2	2.09617167609231
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	2/48	101/9376	3.86798679867987	CXCL8/IL1B	2.07870501528064
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	3/48	214/9376	2.73831775700935	B2M/NFKBIA/GNG10	1.8452401582912
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	5/48	480/9376	2.03472222222222	UBB/UBC/TUBB4B/PSMB3/IL1B	1.6693945681466
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	2/48	105/9376	3.72063492063492	UBB/UBC	2.01100715280794
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	2/48	105/9376	3.72063492063492	NFKBIA/IL1B	2.01100715280794
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	2/48	106/9376	3.68553459119497	HSP90AA1/NFKBIA	1.99459995288149
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	3/48	227/9376	2.58149779735683	SOD2/NFKBIA/CYP1B1	1.73024138034177
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	4/48	362/9376	2.15837937384899	HSP90AA1/EREG/GNG10/SPP1	1.61234625214058
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	2/48	115/9376	3.39710144927536	DUSP1/GNG10	1.85531809690012
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	3/48	238/9376	2.46218487394958	CXCL8/NFKBIA/IL1B	1.63899329436245
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	2/48	120/9376	3.25555555555556	NFKBIA/ARHGDIB	1.78379304675033
Metabolism	Lipid metabolism	hsa00062	Fatty acid elongation	1/48	28/9376	6.97619047619048	PPT1	2.27172670353093
Metabolism	Metabolism of cofactors and vitamins	hsa00790	Folate biosynthesis	1/48	28/9376	6.97619047619048	DHFR	2.27172670353093
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	3/48	250/9376	2.344	HSPA1A/ARPC3/HSPA1B	1.54504463031308
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	2/48	130/9376	3.00512820512821	NFKBIA/GNG10	1.65138701666538
NA	NA	hsa04981	Folate transport and metabolism	1/48	31/9376	6.3010752688172	DHFR	2.12064099637777
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	2/48	137/9376	2.85158150851582	BCL2A1/NFKBIA	1.56603917938851
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	2/48	140/9376	2.79047619047619	GNG10/SPP1	1.53109660706945
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	2/48	142/9376	2.75117370892019	NFKBIA/IL1B	1.50830945554363
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	2/48	143/9376	2.73193473193473	HLA-DQB1/HLA-DRB5	1.49706311660801
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	1/48	38/9376	5.14035087719298	NAPRT	1.83448429868025
Metabolism	Metabolism of cofactors and vitamins	hsa00670	One carbon pool by folate	1/48	39/9376	5.00854700854701	DHFR	1.79939949085735
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	1/48	41/9376	4.76422764227642	CXCL8	1.73269704595956
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	2/48	157/9376	2.48832271762208	CXCL8/IL1B	1.34901574244367
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	3/48	298/9376	1.96644295302013	CXCL8/CXCL2/IL1B	1.21618951427198
NA	NA	hsa04517	IgSF CAM signaling	3/48	299/9376	1.95986622073579	TUBB4B/MYL12A/ARPC3	1.21000488329207
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	2/48	160/9376	2.44166666666667	HLA-DQB1/HLA-DRB5	1.31936695819966
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	1/48	44/9376	4.43939393939394	ARHGDIB	1.64033625182656
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	2/48	163/9376	2.39672801635992	CXCL8/NFKBIA	1.2903784436533
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	3/48	308/9376	1.9025974025974	SOD2/TUBB4B/PSMB3	1.15538219380938
Genetic Information Processing	Folding, sorting and degradation	hsa03050	Proteasome	1/48	46/9376	4.2463768115942	PSMB3	1.58324822477456
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	2/48	169/9376	2.31163708086785	UBB/UBC	1.23426937948607
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	2/48	170/9376	2.29803921568627	MYL12A/ARPC3	1.22514862495768
NA	NA	hsa03272	Virion - Hepatitis viruses	1/48	48/9376	4.06944444444444	CD63	1.52931911004831
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	1/48	52/9376	3.75641025641026	CYP1B1	1.42973775197868
Metabolism	Global and overview maps	hsa01212	Fatty acid metabolism	1/48	57/9376	3.42690058479532	PPT1	1.31830757174214
Cellular Processes	Cell motility	hsa04814	Motor proteins	2/48	194/9376	2.01374570446735	TUBB4B/MYL12A	1.02346556671727
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	2/48	201/9376	1.94361525704809	BCL2A1/CXCL8	0.970067455204575
Genetic Information Processing	Replication and repair	hsa03420	Nucleotide excision repair	1/48	63/9376	3.1005291005291	ERCC5	1.19995832753957
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	2/48	203/9376	1.92446633825944	MYL12A/SPP1	0.955202416771554
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	2/48	204/9376	1.91503267973856	CD63/PLAUR	0.947832625900736
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/48	65/9376	3.00512820512821	SPP1	1.16362394406754
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	1/48	66/9376	2.95959595959596	CYP1B1	1.14597633888765
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	3/48	368/9376	1.59239130434783	TUBB4B/NRG1/PSMB3	0.831630452162256
Metabolism	Metabolism of cofactors and vitamins	hsa00830	Retinol metabolism	1/48	68/9376	2.87254901960784	DHRS4	1.11165865271052
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	1/48	68/9376	2.87254901960784	BCL2A1	1.11165865271052
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/48	70/9376	2.79047619047619	NFKBIA	1.07856924971622
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	2/48	217/9376	1.80030721966206	HSP90AA1/CYP1B1	0.855607455701396
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	3/48	388/9376	1.51030927835052	TUBB4B/PSMB3/IL1B	0.736427137157848
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/48	77/9376	2.53679653679654	NFKBIA	0.971304945671455
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	1/48	78/9376	2.5042735042735	ARPC3	0.95695457857277
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	2/48	232/9376	1.68390804597701	MYL12A/ARPC3	0.756633533523057
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	1/48	79/9376	2.47257383966245	CYP1B1	0.942825237746671
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/48	80/9376	2.44166666666667	NRG1	0.928910305899481
Genetic Information Processing	Transcription	hsa03040	Spliceosome	2/48	243/9376	1.6076817558299	HSPA1A/HSPA1B	0.68846932370698
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	1/48	87/9376	2.24521072796935	EREG	0.837008728039908
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	1/48	89/9376	2.19475655430712	SPP1	0.812360298345766
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/48	89/9376	2.19475655430712	TUBB4B	0.812360298345766
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	1/48	89/9376	2.19475655430712	GNG10	0.812360298345766
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/48	90/9376	2.17037037037037	SOD2	0.800280475840045
Organismal Systems	Digestive system	hsa04976	Bile secretion	1/48	90/9376	2.17037037037037	AQP9	0.800280475840045
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	1/48	90/9376	2.17037037037037	NFKBIA	0.800280475840045
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/48	91/9376	2.14652014652015	NFKBIA	0.788357894258701
Human Diseases	Substance dependence	hsa05032	Morphine addiction	1/48	91/9376	2.14652014652015	GNG10	0.788357894258701
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	1/48	93/9376	2.10035842293907	MYL12A	0.764968336828084
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/48	93/9376	2.10035842293907	NFKBIA	0.764968336828084
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	1/48	97/9376	2.01374570446735	GNG10	0.719906831759898
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	1/48	98/9376	1.99319727891156	ARPC3	0.708978986003173
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/48	99/9376	1.97306397306397	IL1B	0.698179673208098
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	1/48	109/9376	1.79204892966361	NFKBIA	0.596633544541223
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	1/48	110/9376	1.77575757575758	HSP90AA1	0.587067729418981
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	1/48	115/9376	1.69855072463768	GNG10	0.540667063304631
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/48	116/9376	1.68390804597701	MYL12A	0.531659039771366
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	1/48	116/9376	1.68390804597701	GNG10	0.531659039771366
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	1/48	122/9376	1.60109289617486	NFKBIA	0.479367681928078
Organismal Systems	Immune system	hsa04611	Platelet activation	1/48	126/9376	1.55026455026455	MYL12A	0.446064775430031
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	1/48	133/9376	1.468671679198	SOD2	0.390481122406919
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	1/48	133/9376	1.468671679198	GNG10	0.390481122406919
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	1/48	144/9376	1.35648148148148	PSMB3	0.309230491230052
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/48	149/9376	1.31096196868009	CXCL8	0.274461946592315
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	1/48	149/9376	1.31096196868009	GNG10	0.274461946592315
NA	NA	hsa04518	Integrin signaling	1/48	154/9376	1.26839826839827	SPP1	0.240901497267102
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	1/48	156/9376	1.25213675213675	NFKBIA	0.227795416355803
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	1/48	157/9376	1.24416135881104	CXCL8	0.221307860743255
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	1/48	178/9376	1.09737827715356	CACYBP	0.0940886794804782
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/48	184/9376	1.06159420289855	MYL12A	0.0605279173822926
NA	NA	hsa04519	Cadherin signaling	2/48	404/9376	0.966996699669967	NFKBIA/ARPC3	-0.0486424464855969
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/48	191/9376	1.02268760907504	GNG10	0.0227236358919673
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	1/48	195/9376	1.0017094017094	AQP9	0.00173032799415833
NA	NA	hsa04082	Neuroactive ligand signaling	1/48	199/9376	0.981574539363484	GNG10	-0.0188454501031177
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	1/48	205/9376	0.952845528455284	NFKBIA	-0.0489669951125769
NA	NA	hsa04081	Hormone signaling	1/48	219/9376	0.89193302891933	GNG10	-0.116078133900779
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	1/48	226/9376	0.864306784660767	NFKBIA	-0.148120030975575
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	1/48	238/9376	0.820728291316526	GNG10	-0.200949369423748
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	1/48	323/9376	0.604747162022704	CYP1B1	-0.518551608901356