ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0031625	ubiquitin protein ligase binding	9/67	302/18639	0.0298013245033113	8.29055055846595	1.28180514626573e-06	0.00023047213585746
GO:0044389	ubiquitin-like protein ligase binding	9/67	322/18639	0.0279503105590062	7.7756095299898	2.17386892370813e-06	0.00023047213585746
GO:0023026	MHC class II protein complex binding	4/67	27/18639	0.148148148148148	41.2139303482587	2.51424148208138e-06	0.00023047213585746
GO:0023023	MHC protein complex binding	4/67	37/18639	0.108108108108108	30.0750302541347	9.20938283134139e-06	0.000633145069654721
GO:0051082	unfolded protein binding	5/67	121/18639	0.0413223140495868	11.4956210682127	7.42989660733888e-05	0.00292615435112012
GO:0042625	ATPase-coupled ion transmembrane transporter activity	3/67	24/18639	0.125	34.7742537313433	8.51244902144035e-05	0.00292615435112012
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	3/67	24/18639	0.125	34.7742537313433	8.51244902144035e-05	0.00292615435112012
GO:0046961	proton-transporting ATPase activity, rotational mechanism	3/67	24/18639	0.125	34.7742537313433	8.51244902144035e-05	0.00292615435112012
GO:0140662	ATP-dependent protein folding chaperone	3/67	40/18639	0.075	20.864552238806	0.000398792894232772	0.0121853384348902
GO:0042605	peptide antigen binding	3/67	45/18639	0.0666666666666667	18.5462686567164	0.000565459481975573	0.0155501357543283
GO:0008199	ferric iron binding	2/67	11/18639	0.181818181818182	50.5807327001357	0.000685598723076726	0.0157482317511981
GO:0001664	G protein-coupled receptor binding	6/67	297/18639	0.0202020202020202	5.62008141112619	0.000687195567325006	0.0157482317511981
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	3/67	54/18639	0.0555555555555556	15.455223880597	0.000965877122505089	0.0200158219121764
GO:0140313	molecular sequestering activity	3/67	55/18639	0.0545454545454545	15.1742198100407	0.00101898729734716	0.0200158219121764
GO:0031386	protein tag activity	2/67	15/18639	0.133333333333333	37.0925373134328	0.00129677152706133	0.0209771864671686
GO:0140776	protein-containing complex destabilizing activity	2/67	15/18639	0.133333333333333	37.0925373134328	0.00129677152706133	0.0209771864671686
GO:0141047	molecular tag activity	2/67	15/18639	0.133333333333333	37.0925373134328	0.00129677152706133	0.0209771864671686
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/67	17/18639	0.117647058823529	32.7287093942054	0.00167185281882857	0.0255421958432142
GO:0043024	ribosomal small subunit binding	2/67	20/18639	0.1	27.8194029850746	0.00231948789521318	0.0335715353254539
GO:0044183	protein folding chaperone	3/67	75/18639	0.04	11.1277611940299	0.00249192763663426	0.034264005003721
GO:0003823	antigen binding	4/67	174/18639	0.0229885057471264	6.39526505404014	0.00355926539526153	0.0466094277950914
GO:0008198	ferrous iron binding	2/67	26/18639	0.0769230769230769	21.3995407577497	0.00391279934636456	0.0489099918295569
GO:0097718	disordered domain specific binding	2/67	28/18639	0.0714285714285714	19.8710021321962	0.00452987951926551	0.0541616029477398
GO:0042626	ATPase-coupled transmembrane transporter activity	3/67	98/18639	0.0306122448979592	8.51614377094121	0.00529317481648302	0.060650961438868
GO:0030296	protein tyrosine kinase activator activity	2/67	33/18639	0.0606060606060606	16.8602442333786	0.00625474913896972	0.0637057782672842
GO:0140311	protein sequestering activity	2/67	33/18639	0.0606060606060606	16.8602442333786	0.00625474913896972	0.0637057782672842
GO:0140416	transcription regulator inhibitor activity	2/67	33/18639	0.0606060606060606	16.8602442333786	0.00625474913896972	0.0637057782672842
GO:0022853	active monoatomic ion transmembrane transporter activity	3/67	118/18639	0.0254237288135593	7.0727295724766	0.00882859272742819	0.0867093928586697
GO:0005125	cytokine activity	4/67	234/18639	0.0170940170940171	4.75545350172216	0.0100099713660379	0.0949221422641522
GO:0042826	histone deacetylase binding	3/67	127/18639	0.0236220472440945	6.57151251615936	0.010777903228296	0.0987974462593801
GO:0031072	heat shock protein binding	3/67	131/18639	0.0229007633587786	6.37085564543694	0.0117179505046215	0.103949560928094
GO:0042277	peptide binding	4/67	249/18639	0.0160642570281124	4.46898039920877	0.0123518723988706	0.106148903427794
GO:0035254	glutamate receptor binding	2/67	49/18639	0.0408163265306122	11.3548583612549	0.0134266186881335	0.111101012980849
GO:0070851	growth factor receptor binding	3/67	139/18639	0.0215827338129496	6.00418769462042	0.0137361252412687	0.111101012980849
GO:0003743	translation initiation factor activity	2/67	51/18639	0.0392156862745098	10.9095697980685	0.0144901257265667	0.113850987851596
GO:0005506	iron ion binding	3/67	154/18639	0.0194805194805195	5.41936421787168	0.018023485103584	0.137679400096822
GO:0005178	integrin binding	3/67	161/18639	0.0186335403726708	5.18373968665987	0.0202513698599926	0.150516938148593
GO:0015399	primary active transmembrane transporter activity	3/67	166/18639	0.0180722891566265	5.02760294910987	0.02193171732159	0.158716375353612
GO:0015078	proton transmembrane transporter activity	3/67	185/18639	0.0162162162162162	4.51125453812021	0.0289942905208363	0.20444692033923
GO:0001618	virus receptor activity	2/67	81/18639	0.0246913580246914	6.86898839137645	0.0343774519425577	0.205445751435787
GO:0140272	exogenous protein binding	2/67	82/18639	0.024390243902439	6.7852202402621	0.0351566304529187	0.205445751435787
GO:0004090	carbonyl reductase (NADPH) activity	1/67	10/18639	0.1	27.8194029850746	0.0353786216183328	0.205445751435787
GO:0005345	purine nucleobase transmembrane transporter activity	1/67	10/18639	0.1	27.8194029850746	0.0353786216183328	0.205445751435787
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	1/67	10/18639	0.1	27.8194029850746	0.0353786216183328	0.205445751435787
GO:0030957	Tat protein binding	1/67	10/18639	0.1	27.8194029850746	0.0353786216183328	0.205445751435787
GO:0032395	MHC class II receptor activity	1/67	10/18639	0.1	27.8194029850746	0.0353786216183328	0.205445751435787
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/67	10/18639	0.1	27.8194029850746	0.0353786216183328	0.205445751435787
GO:0008135	translation factor activity, RNA binding	2/67	83/18639	0.0240963855421687	6.70347059881316	0.035942665511477	0.205445751435787
GO:0180051	translation factor activity	2/67	84/18639	0.0238095238095238	6.62366737739872	0.0367354993751063	0.205445751435787
GO:0016209	antioxidant activity	2/67	86/18639	0.0232558139534884	6.46962860118015	0.0383413341210732	0.205445751435787
GO:0008432	JUN kinase binding	1/67	11/18639	0.0909090909090909	25.2903663500678	0.0388479239078579	0.205445751435787
GO:0015205	nucleobase transmembrane transporter activity	1/67	11/18639	0.0909090909090909	25.2903663500678	0.0388479239078579	0.205445751435787
GO:0004859	phospholipase inhibitor activity	1/67	12/18639	0.0833333333333333	23.1828358208955	0.0423049342738755	0.211329983311263
GO:0015166	polyol transmembrane transporter activity	1/67	12/18639	0.0833333333333333	23.1828358208955	0.0423049342738755	0.211329983311263
GO:0072341	modified amino acid binding	2/67	91/18639	0.021978021978022	6.1141545022142	0.0424709184252882	0.211329983311263
GO:0005542	folic acid binding	1/67	13/18639	0.0769230769230769	21.3995407577497	0.0457496956097672	0.211329983311263
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	1/67	13/18639	0.0769230769230769	21.3995407577497	0.0457496956097672	0.211329983311263
GO:0008474	palmitoyl-(protein) hydrolase activity	1/67	14/18639	0.0714285714285714	19.8710021321962	0.0491822506615303	0.211329983311263
GO:0032036	myosin heavy chain binding	1/67	14/18639	0.0714285714285714	19.8710021321962	0.0491822506615303	0.211329983311263
GO:0042043	neurexin family protein binding	1/67	14/18639	0.0714285714285714	19.8710021321962	0.0491822506615303	0.211329983311263
GO:0044548	S100 protein binding	1/67	14/18639	0.0714285714285714	19.8710021321962	0.0491822506615303	0.211329983311263
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	1/67	14/18639	0.0714285714285714	19.8710021321962	0.0491822506615303	0.211329983311263
GO:0098599	palmitoyl hydrolase activity	1/67	14/18639	0.0714285714285714	19.8710021321962	0.0491822506615303	0.211329983311263
GO:1990825	sequence-specific mRNA binding	1/67	14/18639	0.0714285714285714	19.8710021321962	0.0491822506615303	0.211329983311263
GO:0015250	water channel activity	1/67	15/18639	0.0666666666666667	18.5462686567164	0.0526026420282782	0.215844948744874
GO:0005149	interleukin-1 receptor binding	1/67	16/18639	0.0625	17.3871268656716	0.0560109121627337	0.215844948744874
GO:0016722	oxidoreductase activity, acting on metal ions	1/67	16/18639	0.0625	17.3871268656716	0.0560109121627337	0.215844948744874
GO:0055102	lipase inhibitor activity	1/67	16/18639	0.0625	17.3871268656716	0.0560109121627337	0.215844948744874
GO:0005539	glycosaminoglycan binding	3/67	242/18639	0.012396694214876	3.4486863204638	0.0564934954713647	0.215844948744874
GO:0005092	GDP-dissociation inhibitor activity	1/67	17/18639	0.0588235294117647	16.3643546971027	0.0594071033717282	0.215844948744874
GO:0045236	CXCR chemokine receptor binding	1/67	17/18639	0.0588235294117647	16.3643546971027	0.0594071033717282	0.215844948744874
GO:0051787	misfolded protein binding	1/67	17/18639	0.0588235294117647	16.3643546971027	0.0594071033717282	0.215844948744874
GO:0070402	NADPH binding	1/67	17/18639	0.0588235294117647	16.3643546971027	0.0594071033717282	0.215844948744874
GO:0005200	structural constituent of cytoskeleton	2/67	112/18639	0.0178571428571429	4.96775053304904	0.0614704077021809	0.215844948744874
GO:0043022	ribosome binding	2/67	112/18639	0.0178571428571429	4.96775053304904	0.0614704077021809	0.215844948744874
GO:0000900	mRNA regulatory element binding translation repressor activity	1/67	18/18639	0.0555555555555556	15.455223880597	0.0627912578166907	0.215844948744874
GO:0005372	water transmembrane transporter activity	1/67	18/18639	0.0555555555555556	15.455223880597	0.0627912578166907	0.215844948744874
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	1/67	18/18639	0.0555555555555556	15.455223880597	0.0627912578166907	0.215844948744874
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/67	18/18639	0.0555555555555556	15.455223880597	0.0627912578166907	0.215844948744874
GO:0098641	cadherin binding involved in cell-cell adhesion	1/67	18/18639	0.0555555555555556	15.455223880597	0.0627912578166907	0.215844948744874
GO:1990782	protein tyrosine kinase binding	2/67	117/18639	0.0170940170940171	4.75545350172216	0.0663532610370623	0.225273417101137
GO:0042288	MHC class I protein binding	1/67	20/18639	0.05	13.9097014925373	0.0695236243361933	0.233158496249429
GO:0070182	DNA polymerase binding	1/67	21/18639	0.0476190476190476	13.2473347547974	0.0728719200110133	0.236354559809936
GO:0008093	cytoskeletal anchor activity	1/67	22/18639	0.0454545454545455	12.6451831750339	0.0762083461233379	0.236354559809936
GO:0008970	phospholipase A1 activity	1/67	22/18639	0.0454545454545455	12.6451831750339	0.0762083461233379	0.236354559809936
GO:0030021	extracellular matrix structural constituent conferring compression resistance	1/67	22/18639	0.0454545454545455	12.6451831750339	0.0762083461233379	0.236354559809936
GO:0033691	sialic acid binding	1/67	22/18639	0.0454545454545455	12.6451831750339	0.0762083461233379	0.236354559809936
GO:0005126	cytokine receptor binding	3/67	275/18639	0.0109090909090909	3.03484396200814	0.0764929302657611	0.236354559809936
GO:1901681	sulfur compound binding	3/67	275/18639	0.0109090909090909	3.03484396200814	0.0764929302657611	0.236354559809936
GO:0031681	G-protein beta-subunit binding	1/67	23/18639	0.0434782608695652	12.0953926022064	0.0795329441149444	0.240531289166562
GO:0004622	lysophospholipase activity	1/67	24/18639	0.0416666666666667	11.5914179104478	0.0828457552851365	0.240531289166562
GO:0005540	hyaluronic acid binding	1/67	24/18639	0.0416666666666667	11.5914179104478	0.0828457552851365	0.240531289166562
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/67	24/18639	0.0416666666666667	11.5914179104478	0.0828457552851365	0.240531289166562
GO:0008139	nuclear localization sequence binding	1/67	25/18639	0.04	11.1277611940299	0.0861468207912284	0.240531289166562
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/67	25/18639	0.04	11.1277611940299	0.0861468207912284	0.240531289166562
GO:0047617	fatty acyl-CoA hydrolase activity	1/67	25/18639	0.04	11.1277611940299	0.0861468207912284	0.240531289166562
GO:0030295	protein kinase activator activity	2/67	139/18639	0.0143884892086331	4.00279179641362	0.0892493381147797	0.240531289166562
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	1/67	26/18639	0.0384615384615385	10.6997703788749	0.0894361816490229	0.240531289166562
GO:0016289	acyl-CoA hydrolase activity	1/67	26/18639	0.0384615384615385	10.6997703788749	0.0894361816490229	0.240531289166562
GO:0050750	low-density lipoprotein particle receptor binding	1/67	26/18639	0.0384615384615385	10.6997703788749	0.0894361816490229	0.240531289166562
GO:0020037	heme binding	2/67	142/18639	0.0140845070422535	3.91822577254572	0.0925329028200912	0.240531289166562
GO:0001671	ATPase activator activity	1/67	27/18639	0.037037037037037	10.3034825870647	0.0927138787332928	0.240531289166562
GO:0008395	steroid hydroxylase activity	1/67	27/18639	0.037037037037037	10.3034825870647	0.0927138787332928	0.240531289166562
GO:0015252	proton channel activity	1/67	27/18639	0.037037037037037	10.3034825870647	0.0927138787332928	0.240531289166562
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	1/67	27/18639	0.037037037037037	10.3034825870647	0.0927138787332928	0.240531289166562
GO:0035255	ionotropic glutamate receptor binding	1/67	27/18639	0.037037037037037	10.3034825870647	0.0927138787332928	0.240531289166562
GO:0045499	chemorepellent activity	1/67	28/18639	0.0357142857142857	9.93550106609808	0.0959799527782565	0.242151257009363
GO:0046875	ephrin receptor binding	1/67	28/18639	0.0357142857142857	9.93550106609808	0.0959799527782565	0.242151257009363
GO:0051019	mitogen-activated protein kinase binding	1/67	28/18639	0.0357142857142857	9.93550106609808	0.0959799527782565	0.242151257009363
GO:0019209	kinase activator activity	2/67	148/18639	0.0135135135135135	3.75937878176684	0.0992043143154487	0.245851100936624
GO:0051861	glycolipid binding	1/67	29/18639	0.0344827586206897	9.59289758106022	0.0992344443780554	0.245851100936624
GO:0001968	fibronectin binding	1/67	30/18639	0.0333333333333333	9.27313432835821	0.102477393987227	0.249391888022012
GO:0008106	alcohol dehydrogenase (NADP+) activity	1/67	30/18639	0.0333333333333333	9.27313432835821	0.102477393987227	0.249391888022012
GO:0046906	tetrapyrrole binding	2/67	152/18639	0.0131578947368421	3.66044776119403	0.103725652831943	0.250215390603371
GO:0047499	calcium-independent phospholipase A2 activity	1/67	31/18639	0.032258064516129	8.9740009629273	0.105708841921176	0.250602858002787
GO:0070325	lipoprotein particle receptor binding	1/67	31/18639	0.032258064516129	8.9740009629273	0.105708841921176	0.250602858002787
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1/67	32/18639	0.03125	8.69356343283582	0.108928828356649	0.251726284017465
GO:0047498	calcium-dependent phospholipase A2 activity	1/67	32/18639	0.03125	8.69356343283582	0.108928828356649	0.251726284017465
GO:0051059	NF-kappaB binding	1/67	32/18639	0.03125	8.69356343283582	0.108928828356649	0.251726284017465
GO:0008083	growth factor activity	2/67	162/18639	0.0123456790123457	3.43449419568823	0.115268750544146	0.255108373704536
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	1/67	34/18639	0.0294117647058824	8.18217734855136	0.115334576748666	0.255108373704536
GO:0019825	oxygen binding	1/67	34/18639	0.0294117647058824	8.18217734855136	0.115334576748666	0.255108373704536
GO:0003924	GTPase activity	3/67	331/18639	0.00906344410876133	2.52139604094332	0.116413532587611	0.255108373704536
GO:0004623	phospholipase A2 activity	1/67	35/18639	0.0285714285714286	7.94840085287846	0.118520418369619	0.255108373704536
GO:0005154	epidermal growth factor receptor binding	1/67	35/18639	0.0285714285714286	7.94840085287846	0.118520418369619	0.255108373704536
GO:0016229	steroid dehydrogenase activity	1/67	35/18639	0.0285714285714286	7.94840085287846	0.118520418369619	0.255108373704536
GO:0061631	ubiquitin conjugating enzyme activity	1/67	35/18639	0.0285714285714286	7.94840085287846	0.118520418369619	0.255108373704536
GO:0045296	cadherin binding	3/67	334/18639	0.00898203592814371	2.49874877111449	0.118741352124293	0.255108373704536
GO:0016874	ligase activity	2/67	167/18639	0.0119760479041916	3.33166502815265	0.121159755405052	0.25546651451151
GO:0000993	RNA polymerase II complex binding	1/67	36/18639	0.0277777777777778	7.72761194029851	0.121694957821846	0.25546651451151
GO:0004033	aldo-keto reductase (NADPH) activity	1/67	36/18639	0.0277777777777778	7.72761194029851	0.121694957821846	0.25546651451151
GO:0043394	proteoglycan binding	1/67	37/18639	0.027027027027027	7.51875756353368	0.124858234595804	0.260121322074592
GO:0008201	heparin binding	2/67	172/18639	0.0116279069767442	3.23481430059007	0.127124313183263	0.26076169787165
GO:0005109	frizzled binding	1/67	38/18639	0.0263157894736842	7.32089552238806	0.128010288046083	0.26076169787165
GO:0042887	amide transmembrane transporter activity	1/67	38/18639	0.0263157894736842	7.32089552238806	0.128010288046083	0.26076169787165
GO:0000217	DNA secondary structure binding	1/67	39/18639	0.0256410256410256	7.13318025258324	0.131151157391866	0.265195355020317
GO:0043021	ribonucleoprotein complex binding	2/67	177/18639	0.0112994350282486	3.14343536554516	0.133158026872205	0.267288010144937
GO:0015144	carbohydrate transmembrane transporter activity	1/67	40/18639	0.025	6.95485074626866	0.13428088171739	0.267588713567262
GO:0042287	MHC protein binding	1/67	41/18639	0.024390243902439	6.7852202402621	0.1373994999724	0.269891874945786
GO:0061650	ubiquitin-like protein conjugating enzyme activity	1/67	41/18639	0.024390243902439	6.7852202402621	0.1373994999724	0.269891874945786
GO:0004520	DNA endonuclease activity	1/67	42/18639	0.0238095238095238	6.62366737739872	0.140507050972607	0.272108725475119
GO:0043175	RNA polymerase core enzyme binding	1/67	42/18639	0.0238095238095238	6.62366737739872	0.140507050972607	0.272108725475119
GO:0048156	tau protein binding	1/67	43/18639	0.0232558139534884	6.46962860118015	0.14360357340014	0.276160718077193
GO:0031406	carboxylic acid binding	2/67	187/18639	0.0106951871657754	2.97533721765504	0.145415977024736	0.277704122790294
GO:0016790	thiolester hydrolase activity	1/67	44/18639	0.0227272727272727	6.32259158751696	0.146689105804001	0.278203476524829
GO:0043177	organic acid binding	2/67	189/18639	0.0105820105820106	2.94385216773276	0.147895821155564	0.278570896012193
GO:0008009	chemokine activity	1/67	45/18639	0.0222222222222222	6.18208955223881	0.149763686600513	0.280170162007762
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/67	46/18639	0.0217391304347826	6.04769630110318	0.15282735407377	0.283969745745182
GO:0043495	protein-membrane adaptor activity	1/67	47/18639	0.0212765957446809	5.91902191171801	0.155880146376092	0.287698256734398
GO:0016879	ligase activity, forming carbon-nitrogen bonds	1/67	48/18639	0.0208333333333333	5.79570895522388	0.158922101528459	0.28942766834653
GO:0038187	pattern recognition receptor activity	1/67	48/18639	0.0208333333333333	5.79570895522388	0.158922101528459	0.28942766834653
GO:0060590	ATPase regulator activity	1/67	49/18639	0.0204081632653061	5.67742918062747	0.161953257420965	0.293007538097141
GO:0005048	signal sequence binding	1/67	51/18639	0.0196078431372549	5.45478489903424	0.167983322334996	0.29997021845535
GO:0030544	Hsp70 protein binding	1/67	51/18639	0.0196078431372549	5.45478489903424	0.167983322334996	0.29997021845535
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	1/67	52/18639	0.0192307692307692	5.34988518943743	0.170982306486252	0.303355705056254
GO:0005544	calcium-dependent phospholipid binding	1/67	53/18639	0.0188679245283019	5.24894395944804	0.173970641637994	0.304725646181199
GO:0008146	sulfotransferase activity	1/67	53/18639	0.0188679245283019	5.24894395944804	0.173970641637994	0.304725646181199
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	1/67	54/18639	0.0185185185185185	5.15174129353234	0.176948365032498	0.306042769710295
GO:0050661	NADP binding	1/67	54/18639	0.0185185185185185	5.15174129353234	0.176948365032498	0.306042769710295
GO:0098632	cell-cell adhesion mediator activity	1/67	55/18639	0.0181818181818182	5.05807327001357	0.179915513783794	0.309229789315895
GO:0004857	enzyme inhibitor activity	3/67	416/18639	0.00721153846153846	2.00620694603904	0.188300198743608	0.319215805502584
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	1/67	58/18639	0.0172413793103448	4.79644879053011	0.188753881404097	0.319215805502584
GO:0016887	ATP hydrolysis activity	3/67	417/18639	0.00719424460431655	2.00139589820681	0.189207913806986	0.319215805502584
GO:0001786	phosphatidylserine binding	1/67	59/18639	0.0169491525423729	4.71515304831773	0.191679100173051	0.319465166955085
GO:0070063	RNA polymerase binding	1/67	59/18639	0.0169491525423729	4.71515304831773	0.191679100173051	0.319465166955085
GO:0001098	basal transcription machinery binding	1/67	60/18639	0.0166666666666667	4.6365671641791	0.194593927960371	0.320439102928755
GO:0001099	basal RNA polymerase II transcription machinery binding	1/67	60/18639	0.0166666666666667	4.6365671641791	0.194593927960371	0.320439102928755
GO:0016836	hydro-lyase activity	1/67	61/18639	0.0163934426229508	4.56055786640568	0.197498401119672	0.323286073261368
GO:0004536	DNA nuclease activity	1/67	64/18639	0.015625	4.34678171641791	0.206150054489618	0.33545127209849
GO:0160215	deacylase activity	1/67	65/18639	0.0153846153846154	4.27990815154994	0.209013470174635	0.338110025282498
GO:0050840	extracellular matrix binding	1/67	67/18639	0.0149253731343284	4.15214969926487	0.21470981296318	0.345293558858916
GO:0030145	manganese ion binding	1/67	68/18639	0.0147058823529412	4.09108867427568	0.217542811161084	0.347815541100571
GO:0016782	transferase activity, transferring sulphur-containing groups	1/67	70/18639	0.0142857142857143	3.97420042643923	0.223178637982272	0.352724858880028
GO:0097110	scaffold protein binding	1/67	70/18639	0.0142857142857143	3.97420042643923	0.223178637982272	0.352724858880028
GO:0022804	active transmembrane transporter activity	3/67	457/18639	0.00656455142231947	1.8262190143375	0.226380421313466	0.355740662064018
GO:0042379	chemokine receptor binding	1/67	72/18639	0.0138888888888889	3.86380597014925	0.228774473041481	0.357460114127314
GO:0019887	protein kinase regulator activity	2/67	255/18639	0.00784313725490196	2.1819139596137	0.233324268015427	0.362027605948255
GO:0003684	damaged DNA binding	1/67	74/18639	0.0135135135135135	3.75937878176684	0.234330595850143	0.362027605948255
GO:0003725	double-stranded RNA binding	1/67	75/18639	0.0133333333333333	3.70925373134328	0.237093851981468	0.363040508322248
GO:0017022	myosin binding	1/67	76/18639	0.0131578947368421	3.66044776119403	0.239847283995971	0.363040508322248
GO:0098631	cell adhesion mediator activity	1/67	76/18639	0.0131578947368421	3.66044776119403	0.239847283995971	0.363040508322248
GO:0016835	carbon-oxygen lyase activity	1/67	79/18639	0.0126582278481013	3.52144341583223	0.248048978746129	0.363040508322248
GO:0048306	calcium-dependent protein binding	1/67	80/18639	0.0125	3.47742537313433	0.250763457109492	0.363040508322248
GO:0030971	receptor tyrosine kinase binding	1/67	81/18639	0.0123456790123457	3.43449419568823	0.253468282174079	0.363040508322248
GO:0033192	calmodulin-dependent protein phosphatase activity	1/67	81/18639	0.0123456790123457	3.43449419568823	0.253468282174079	0.363040508322248
GO:0140791	histone H2AXS140 phosphatase activity	1/67	81/18639	0.0123456790123457	3.43449419568823	0.253468282174079	0.363040508322248
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	1/67	81/18639	0.0123456790123457	3.43449419568823	0.253468282174079	0.363040508322248
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	1/67	81/18639	0.0123456790123457	3.43449419568823	0.253468282174079	0.363040508322248
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	1/67	81/18639	0.0123456790123457	3.43449419568823	0.253468282174079	0.363040508322248
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	1/67	81/18639	0.0123456790123457	3.43449419568823	0.253468282174079	0.363040508322248
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	1/67	81/18639	0.0123456790123457	3.43449419568823	0.253468282174079	0.363040508322248
GO:1990439	MAP kinase serine/threonine phosphatase activity	1/67	81/18639	0.0123456790123457	3.43449419568823	0.253468282174079	0.363040508322248
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	1/67	82/18639	0.0121951219512195	3.39261012013105	0.256163487750883	0.363118346038622
GO:0033549	MAP kinase phosphatase activity	1/67	82/18639	0.0121951219512195	3.39261012013105	0.256163487750883	0.363118346038622
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	1/67	83/18639	0.0120481927710843	3.35173529940658	0.25884910753429	0.363181145775152
GO:0005254	chloride channel activity	1/67	83/18639	0.0120481927710843	3.35173529940658	0.25884910753429	0.363181145775152
GO:0017018	myosin phosphatase activity	1/67	84/18639	0.0119047619047619	3.31183368869936	0.261525175102473	0.365073213975533
GO:0005543	phospholipid binding	3/67	497/18639	0.00603621730382294	1.67923961680531	0.264860516803156	0.366917082574844
GO:0030246	carbohydrate binding	2/67	280/18639	0.00714285714285714	1.98710021321962	0.266634367604509	0.366917082574844
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	1/67	86/18639	0.0116279069767442	3.23481430059007	0.266848787327159	0.366917082574844
GO:0016651	oxidoreductase activity, acting on NAD(P)H	1/67	88/18639	0.0113636363636364	3.16129579375848	0.272134590741032	0.372029255596525
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	1/67	89/18639	0.0112359550561798	3.12577561630052	0.274763396865787	0.372029255596525
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	1/67	89/18639	0.0112359550561798	3.12577561630052	0.274763396865787	0.372029255596525
GO:0019207	kinase regulator activity	2/67	287/18639	0.00696864111498258	1.9386343543606	0.275978065969786	0.372029255596525
GO:0140793	histone H2AXY142 phosphatase activity	1/67	90/18639	0.0111111111111111	3.0910447761194	0.277382849825895	0.372098944888396
GO:0052689	carboxylic ester hydrolase activity	1/67	92/18639	0.0108695652173913	3.02384815055159	0.282593827241708	0.377249041220727
GO:0051213	dioxygenase activity	1/67	93/18639	0.010752688172043	2.9913336543091	0.285185416909838	0.378869515218383
GO:0004867	serine-type endopeptidase inhibitor activity	1/67	95/18639	0.0105263157894737	2.92835820895522	0.290340960354588	0.383864250468807
GO:0004725	protein tyrosine phosphatase activity	1/67	98/18639	0.0102040816326531	2.83871459031374	0.298005669005585	0.39211272237577
GO:0004722	protein serine/threonine phosphatase activity	1/67	103/18639	0.00970873786407767	2.70091291117229	0.310599360024941	0.404809592449568
GO:0005253	monoatomic anion channel activity	1/67	103/18639	0.00970873786407767	2.70091291117229	0.310599360024941	0.404809592449568
GO:0051020	GTPase binding	2/67	315/18639	0.00634920634920635	1.76631130063966	0.313261397252634	0.406353227568275
GO:0004497	monooxygenase activity	1/67	106/18639	0.00943396226415094	2.62447197972402	0.31804846893751	0.410625957548429
GO:0004620	phospholipase activity	1/67	109/18639	0.00917431192660551	2.55223880597015	0.325418277299847	0.418177692791859
GO:1902936	phosphatidylinositol bisphosphate binding	1/67	111/18639	0.00900900900900901	2.50625252117789	0.33028783800909	0.422461188151161
GO:0003697	single-stranded DNA binding	1/67	121/18639	0.00826446280991736	2.29912421364253	0.354121007937529	0.448770862593643
GO:0015108	chloride transmembrane transporter activity	1/67	121/18639	0.00826446280991736	2.29912421364253	0.354121007937529	0.448770862593643
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1/67	122/18639	0.00819672131147541	2.28027893320284	0.356457863562769	0.449532630644578
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	2/67	349/18639	0.00573065902578797	1.59423512808451	0.357991440404228	0.449532630644578
GO:0004519	endonuclease activity	1/67	127/18639	0.0078740157480315	2.19050417205312	0.368017786420204	0.460022233025255
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	1/67	128/18639	0.0078125	2.17339085820896	0.370305103204444	0.460786893127701
GO:0016298	lipase activity	1/67	130/18639	0.00769230769230769	2.13995407577497	0.374855299487006	0.464347780896066
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	1/67	132/18639	0.00757575757575758	2.10753052917232	0.379373103148924	0.467836786394413
GO:0051087	protein-folding chaperone binding	1/67	134/18639	0.00746268656716418	2.07607484963243	0.383858741322199	0.47042255895111
GO:0019838	growth factor binding	1/67	136/18639	0.00735294117647059	2.04554433713784	0.388312439570552	0.47042255895111
GO:0044325	transmembrane transporter binding	1/67	136/18639	0.00735294117647059	2.04554433713784	0.388312439570552	0.47042255895111
GO:0140789	histone phosphatase activity	1/67	136/18639	0.00735294117647059	2.04554433713784	0.388312439570552	0.47042255895111
GO:0005525	GTP binding	2/67	378/18639	0.00529100529100529	1.47192608386638	0.395343998816092	0.476840349449233
GO:0019903	protein phosphatase binding	1/67	144/18639	0.00694444444444444	1.93190298507463	0.405812290294269	0.487329169567354
GO:0008509	monoatomic anion transmembrane transporter activity	1/67	149/18639	0.00671140939597315	1.86707402584393	0.416498266923881	0.497987058278554
GO:0019842	vitamin binding	1/67	150/18639	0.00666666666666667	1.85462686567164	0.418612632316856	0.498348371805781
GO:0019001	guanyl nucleotide binding	2/67	400/18639	0.005	1.39097014925373	0.423038953319205	0.499294901986187
GO:0032561	guanyl ribonucleotide binding	2/67	400/18639	0.005	1.39097014925373	0.423038953319205	0.499294901986187
GO:0004175	endopeptidase activity	2/67	405/18639	0.00493827160493827	1.37379767827529	0.429246284091948	0.504456103099512
GO:0140375	immune receptor activity	1/67	156/18639	0.00641025641025641	1.78329506314581	0.43114125001004	0.5045269946926
GO:0004866	endopeptidase inhibitor activity	1/67	161/18639	0.0062111801242236	1.72791322888662	0.441378300787792	0.514317935240012
GO:0015103	inorganic anion transmembrane transporter activity	1/67	165/18639	0.00606060606060606	1.68602442333786	0.449437091984897	0.521498735425513
GO:0005201	extracellular matrix structural constituent	1/67	168/18639	0.00595238095238095	1.65591684434968	0.455405925642231	0.526204325847116
GO:0030414	peptidase inhibitor activity	1/67	169/18639	0.00591715976331361	1.6461185198269	0.457381335905994	0.526275595707734
GO:0004721	phosphoprotein phosphatase activity	1/67	175/18639	0.00571428571428571	1.58968017057569	0.469086428003008	0.537462904014208
GO:0004252	serine-type endopeptidase activity	1/67	176/18639	0.00568181818181818	1.58064789687924	0.471012944972452	0.537462904014208
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	1/67	181/18639	0.00552486187845304	1.53698359033561	0.48054271219613	0.543603688594327
GO:0005216	monoatomic ion channel activity	2/67	448/18639	0.00446428571428571	1.24193763326226	0.481151003152363	0.543603688594327
GO:0004842	ubiquitin-protein transferase activity	2/67	449/18639	0.0044543429844098	1.23917162517036	0.482324727334603	0.543603688594327
GO:0061135	endopeptidase regulator activity	1/67	184/18639	0.00543478260869565	1.51192407527579	0.48617918377243	0.545578297150407
GO:1901981	phosphatidylinositol phosphate binding	1/67	185/18639	0.00540540540540541	1.50375151270674	0.488044585814546	0.545578297150407
GO:0019902	phosphatase binding	1/67	190/18639	0.00526315789473684	1.46417910447761	0.49727199176122	0.553642905807026
GO:0008236	serine-type peptidase activity	1/67	194/18639	0.00515463917525773	1.43398984459148	0.504535788031941	0.559465087535418
GO:0017171	serine hydrolase activity	1/67	198/18639	0.00505050505050505	1.40502035278155	0.511696175589056	0.565126298341327
GO:0016829	lyase activity	1/67	200/18639	0.005	1.39097014925373	0.515238045058373	0.56619758904272
GO:0019787	ubiquitin-like protein transferase activity	2/67	479/18639	0.00417536534446764	1.1615617112766	0.516783981271719	0.56619758904272
GO:0003714	transcription corepressor activity	1/67	204/18639	0.00490196078431373	1.36369622475856	0.522246032312663	0.569911344785645
GO:0140297	DNA-binding transcription factor binding	2/67	488/18639	0.00409836065573771	1.14013946660142	0.526830360570553	0.572502341899349
GO:0004518	nuclease activity	1/67	209/18639	0.00478468899521531	1.33107191316147	0.530865807943033	0.572502341899349
GO:0051015	actin filament binding	1/67	209/18639	0.00478468899521531	1.33107191316147	0.530865807943033	0.572502341899349
GO:0003712	transcription coregulator activity	2/67	495/18639	0.00404040404040404	1.12401628222524	0.53454893407549	0.573160705199744
GO:0016755	aminoacyltransferase activity	2/67	496/18639	0.00403225806451613	1.12175012036591	0.535644731768488	0.573160705199744
GO:0061134	peptidase regulator activity	1/67	226/18639	0.00442477876106195	1.23094703473782	0.559042767881943	0.595878919254009
GO:0033218	amide binding	1/67	247/18639	0.00404858299595142	1.12629161882893	0.591556561441755	0.628100596125415
GO:0005096	GTPase activator activity	1/67	271/18639	0.003690036900369	1.02654623561161	0.625830247899424	0.661935839124391
GO:0016791	phosphatase activity	1/67	273/18639	0.00366300366300366	1.01902575036903	0.62855502264163	0.662270617725855
GO:0031267	small GTPase binding	1/67	283/18639	0.00353356890459364	0.983017773324192	0.64188842024329	0.672542864198137
GO:0035091	phosphatidylinositol binding	1/67	284/18639	0.00352112676056338	0.979556443136431	0.643195539214946	0.672542864198137
GO:0030371	translation repressor activity	1/67	329/18639	0.00303951367781155	0.845574558816858	0.697394784802873	0.726452900836327
GO:0140097	catalytic activity, acting on DNA	1/67	336/18639	0.00297619047619048	0.82795842217484	0.705062512984173	0.731668645549614
GO:0005261	monoatomic cation channel activity	1/67	341/18639	0.00293255131964809	0.815818269357027	0.710421961029764	0.734458794297689
GO:0061630	ubiquitin protein ligase activity	1/67	353/18639	0.0028328611898017	0.788085070398715	0.722896330361645	0.744556145503567
GO:0045182	translation regulator activity	1/67	356/18639	0.00280898876404494	0.78144390407513	0.725931276965493	0.744892168528024
GO:0042578	phosphoric ester hydrolase activity	1/67	363/18639	0.00275482093663912	0.766374737880844	0.732886062347114	0.749232963366008
GO:0046982	protein heterodimerization activity	1/67	369/18639	0.002710027100271	0.753913360029123	0.738708719703874	0.752388510809502
GO:0061659	ubiquitin-like protein ligase activity	1/67	372/18639	0.00268817204301075	0.747833413577275	0.741572980032458	0.752518706675004
GO:0015631	tubulin binding	1/67	385/18639	0.0025974025974026	0.722581895716224	0.753631511296547	0.761943623553494
GO:0003779	actin binding	1/67	443/18639	0.00225733634311512	0.627977494019743	0.801017369658844	0.806885628777224
GO:0030695	GTPase regulator activity	1/67	489/18639	0.00204498977505112	0.568903946525044	0.832108744644279	0.832728508507025
GO:0060589	nucleoside-triphosphatase regulator activity	1/67	490/18639	0.00204081632653061	0.567742918062747	0.832728508507025	0.832728508507025