ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0019957 C-C chemokine binding 5/227 24/18639 0.208333333333333 17.1062775330396 9.02130601455886e-06 0.00516018704032767 GO:0140375 immune receptor activity 10/227 156/18639 0.0641025641025641 5.26347001016604 2.19112208190058e-05 0.00619156810350112 GO:0002020 protease binding 9/227 136/18639 0.0661764705882353 5.43375874578906 4.41285218433586e-05 0.00619156810350112 GO:0019956 chemokine binding 5/227 33/18639 0.151515151515152 12.4409291149379 4.60709611404101e-05 0.00619156810350112 GO:0048306 calcium-dependent protein binding 7/227 80/18639 0.0875 7.18463656387665 5.4122098806828e-05 0.00619156810350112 GO:0016493 C-C chemokine receptor activity 4/227 23/18639 0.173913043478261 14.2800229841027 0.000158156619001466 0.014078209406651 GO:0004896 cytokine receptor activity 7/227 96/18639 0.0729166666666667 5.98719713656388 0.000172285779452022 0.014078209406651 GO:0001637 G protein-coupled chemoattractant receptor activity 4/227 26/18639 0.153846153846154 12.6323280243985 0.000259477278354227 0.0156530447828534 GO:0004950 chemokine receptor activity 4/227 26/18639 0.153846153846154 12.6323280243985 0.000259477278354227 0.0156530447828534 GO:0050786 RAGE receptor binding 3/227 11/18639 0.272727272727273 22.3936724068883 0.000273654629070863 0.0156530447828534 GO:0019955 cytokine binding 8/227 144/18639 0.0555555555555556 4.56167400881057 0.000389395229604091 0.0190953854229308 GO:0051861 glycolipid binding 4/227 29/18639 0.137931034482759 11.3255354701504 0.000400602491390157 0.0190953854229308 GO:0035325 Toll-like receptor binding 3/227 13/18639 0.230769230769231 18.9484920365978 0.000465862134330022 0.020497933910521 GO:0004857 enzyme inhibitor activity 14/227 416/18639 0.0336538461538462 2.76332175533717 0.000607342622167397 0.0248142842771251 GO:0038187 pattern recognition receptor activity 4/227 48/18639 0.0833333333333333 6.84251101321586 0.00274010875405272 0.104489480487877 GO:0001618 virus receptor activity 5/227 81/18639 0.0617283950617284 5.06852667645619 0.00310067493501084 0.110022403618917 GO:0140272 exogenous protein binding 5/227 82/18639 0.0609756097560976 5.0067153755238 0.00326989661105172 0.110022403618917 GO:0004866 endopeptidase inhibitor activity 7/227 161/18639 0.0434782608695652 3.57000574602567 0.00362882623232848 0.115316033605105 GO:0140313 molecular sequestering activity 4/227 55/18639 0.0727272727272727 5.9716459751702 0.00449546516250627 0.135229247486726 GO:0030414 peptidase inhibitor activity 7/227 169/18639 0.0414201183431953 3.40101139118421 0.00472829536666874 0.135229247486726 GO:1905394 retromer complex binding 2/227 10/18639 0.2 16.4220264317181 0.00623081495820671 0.165928103186861 GO:0061134 peptidase regulator activity 8/227 226/18639 0.0353982300884956 2.90655335074656 0.00662368377866175 0.165928103186861 GO:0140311 protein sequestering activity 3/227 33/18639 0.0909090909090909 7.46455746896276 0.00743016490956237 0.165928103186861 GO:0061135 endopeptidase regulator activity 7/227 184/18639 0.0380434782608696 3.12375502777246 0.00744385914049953 0.165928103186861 GO:0008199 ferric iron binding 2/227 11/18639 0.181818181818182 14.9291149379255 0.00755462836468134 0.165928103186861 GO:0019864 IgG binding 2/227 11/18639 0.181818181818182 14.9291149379255 0.00755462836468134 0.165928103186861 GO:0045296 cadherin binding 10/227 334/18639 0.029940119760479 2.45838719037696 0.00803147486559479 0.165928103186861 GO:0120013 lipid transfer activity 4/227 65/18639 0.0615384615384615 5.0529312097594 0.00812235470145472 0.165928103186861 GO:0004869 cysteine-type endopeptidase inhibitor activity 3/227 36/18639 0.0833333333333333 6.84251101321586 0.00946756566767681 0.186739571100384 GO:0031625 ubiquitin protein ligase binding 9/227 302/18639 0.0298013245033113 2.44699069346792 0.0119756098554162 0.20529769371319 GO:0008191 metalloendopeptidase inhibitor activity 2/227 14/18639 0.142857142857143 11.7300188797986 0.0122030097661686 0.20529769371319 GO:0008474 palmitoyl-(protein) hydrolase activity 2/227 14/18639 0.142857142857143 11.7300188797986 0.0122030097661686 0.20529769371319 GO:0019763 immunoglobulin receptor activity 2/227 14/18639 0.142857142857143 11.7300188797986 0.0122030097661686 0.20529769371319 GO:0098599 palmitoyl hydrolase activity 2/227 14/18639 0.142857142857143 11.7300188797986 0.0122030097661686 0.20529769371319 GO:0001530 lipopolysaccharide binding 3/227 41/18639 0.0731707317073171 6.00805845062856 0.0135219309213236 0.220986985342775 GO:0050700 CARD domain binding 2/227 15/18639 0.133333333333333 10.9480176211454 0.0139684079992528 0.221942482654794 GO:0033293 monocarboxylic acid binding 4/227 79/18639 0.0506329113924051 4.15747504600457 0.0158103231751982 0.238389347685208 GO:0005149 interleukin-1 receptor binding 2/227 16/18639 0.125 10.2637665198238 0.0158370545664998 0.238389347685208 GO:0044389 ubiquitin-like protein ligase binding 9/227 322/18639 0.0279503105590062 2.29500369387364 0.0174947321308397 0.254628599675613 GO:0036041 long-chain fatty acid binding 2/227 17/18639 0.117647058823529 9.66001554806945 0.0178061957815114 0.254628599675613 GO:0005504 fatty acid binding 3/227 47/18639 0.0638297872340425 5.24107226544193 0.0195059988403453 0.27213247162628 GO:0005520 insulin-like growth factor binding 2/227 19/18639 0.105263157894737 8.6431718061674 0.022035202788278 0.294965170749948 GO:0031072 heat shock protein binding 5/227 131/18639 0.0381679389312977 3.13397450986986 0.0221739551437898 0.294965170749948 GO:0008373 sialyltransferase activity 2/227 21/18639 0.0952380952380952 7.82001258653241 0.0266344095028232 0.338552938569219 GO:0019200 carbohydrate kinase activity 2/227 21/18639 0.0952380952380952 7.82001258653241 0.0266344095028232 0.338552938569219 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 3/227 54/18639 0.0555555555555556 4.56167400881057 0.0280553805243985 0.341439950211828 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 3/227 54/18639 0.0555555555555556 4.56167400881057 0.0280553805243985 0.341439950211828 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/227 22/18639 0.0909090909090909 7.46455746896276 0.0290664833170932 0.346375592862028 GO:0031681 G-protein beta-subunit binding 2/227 23/18639 0.0869565217391304 7.14001149205133 0.0315835771024077 0.361316122051544 GO:0043274 phospholipase binding 2/227 23/18639 0.0869565217391304 7.14001149205133 0.0315835771024077 0.361316122051544 GO:0042625 ATPase-coupled ion transmembrane transporter activity 2/227 24/18639 0.0833333333333333 6.84251101321586 0.0341832788534223 0.368921424606747 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 2/227 24/18639 0.0833333333333333 6.84251101321586 0.0341832788534223 0.368921424606747 GO:0046961 proton-transporting ATPase activity, rotational mechanism 2/227 24/18639 0.0833333333333333 6.84251101321586 0.0341832788534223 0.368921424606747 GO:0015459 potassium channel regulator activity 3/227 59/18639 0.0508474576271186 4.17509146569103 0.0351933619367379 0.37278894495952 GO:0004709 MAP kinase kinase kinase activity 2/227 25/18639 0.08 6.56881057268722 0.0368632222483652 0.376531484394016 GO:0120020 cholesterol transfer activity 2/227 25/18639 0.08 6.56881057268722 0.0368632222483652 0.376531484394016 GO:0015026 coreceptor activity 3/227 61/18639 0.0491803278688525 4.03820322091428 0.0382861484609363 0.377721018933892 GO:0008157 protein phosphatase 1 binding 2/227 26/18639 0.0769230769230769 6.31616401219926 0.0396210859021565 0.377721018933892 GO:0008198 ferrous iron binding 2/227 26/18639 0.0769230769230769 6.31616401219926 0.0396210859021565 0.377721018933892 GO:0019865 immunoglobulin binding 2/227 26/18639 0.0769230769230769 6.31616401219926 0.0396210859021565 0.377721018933892 GO:0019888 protein phosphatase regulator activity 4/227 107/18639 0.0373831775700935 3.06953765078842 0.041880850855213 0.392718798183309 GO:0099106 ion channel regulator activity 5/227 160/18639 0.03125 2.56594162995595 0.0463091686684816 0.427239427070508 GO:0003924 GTPase activity 8/227 331/18639 0.0241691842900302 1.98453491621971 0.0503013117170628 0.456703973050157 GO:0035925 mRNA 3'-UTR AU-rich region binding 2/227 30/18639 0.0666666666666667 5.47400881057269 0.0513868473055459 0.459269947793316 GO:0019208 phosphatase regulator activity 4/227 117/18639 0.0341880341880342 2.80718400542189 0.0548807775395676 0.476155454043503 GO:0016247 channel regulator activity 5/227 168/18639 0.0297619047619048 2.44375393329138 0.0549410139280965 0.476155454043503 GO:0141108 transporter regulator activity 5/227 170/18639 0.0294117647058824 2.41500388701736 0.057234999216743 0.485191216322562 GO:0120015 sterol transfer activity 2/227 32/18639 0.0625 5.13188325991189 0.0576800746677172 0.485191216322562 GO:0008201 heparin binding 5/227 172/18639 0.0290697674418605 2.38692244647065 0.0595833797989608 0.490808260232299 GO:0071889 14-3-3 protein binding 2/227 33/18639 0.0606060606060606 4.97637164597517 0.0609220043295336 0.490808260232299 GO:0140416 transcription regulator inhibitor activity 2/227 33/18639 0.0606060606060606 4.97637164597517 0.0609220043295336 0.490808260232299 GO:0015035 protein-disulfide reductase activity 2/227 34/18639 0.0588235294117647 4.83000777403472 0.0642248149161001 0.510230474055684 GO:0061631 ubiquitin conjugating enzyme activity 2/227 35/18639 0.0571428571428571 4.69200755191945 0.0675865576730278 0.529582342314684 GO:0005539 glycosaminoglycan binding 6/227 242/18639 0.0247933884297521 2.03578840062621 0.0761657918174986 0.563707417659797 GO:0005501 retinoid binding 2/227 38/18639 0.0526315789473684 4.3215859030837 0.0780064585847173 0.563707417659797 GO:0019840 isoprenoid binding 2/227 38/18639 0.0526315789473684 4.3215859030837 0.0780064585847173 0.563707417659797 GO:0031406 carboxylic acid binding 5/227 187/18639 0.0267379679144385 2.19545807910669 0.078918665480187 0.563707417659797 GO:0043177 organic acid binding 5/227 189/18639 0.0264550264550265 2.17222571848122 0.08172377763415 0.563707417659797 GO:0044325 transmembrane transporter binding 4/227 136/18639 0.0294117647058824 2.41500388701736 0.0848558418600152 0.563707417659797 GO:0015036 disulfide oxidoreductase activity 2/227 40/18639 0.05 4.10550660792952 0.0852136769162208 0.563707417659797 GO:0140662 ATP-dependent protein folding chaperone 2/227 40/18639 0.05 4.10550660792952 0.0852136769162208 0.563707417659797 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 2/227 41/18639 0.0487804878048781 4.00537230041904 0.0888901767108309 0.563707417659797 GO:0017080 sodium channel regulator activity 2/227 41/18639 0.0487804878048781 4.00537230041904 0.0888901767108309 0.563707417659797 GO:0061650 ubiquitin-like protein conjugating enzyme activity 2/227 41/18639 0.0487804878048781 4.00537230041904 0.0888901767108309 0.563707417659797 GO:0003727 single-stranded RNA binding 3/227 89/18639 0.0337078651685393 2.76775726377271 0.0948026355080544 0.563707417659797 GO:0019210 kinase inhibitor activity 3/227 90/18639 0.0333333333333333 2.73700440528634 0.0972348206654758 0.563707417659797 GO:0019903 protein phosphatase binding 4/227 144/18639 0.0277777777777778 2.28083700440529 0.0994406316554942 0.563707417659797 GO:0046873 metal ion transmembrane transporter activity 9/227 450/18639 0.02 1.64220264317181 0.100093620823092 0.563707417659797 GO:0016790 thiolester hydrolase activity 2/227 44/18639 0.0454545454545455 3.73227873448138 0.100190995533323 0.563707417659797 GO:0043178 alcohol binding 3/227 92/18639 0.0326086956521739 2.67750430951925 0.102174545389768 0.563707417659797 GO:0042605 peptide antigen binding 2/227 45/18639 0.0444444444444444 3.64933920704846 0.104042947312989 0.563707417659797 GO:0015085 calcium ion transmembrane transporter activity 4/227 147/18639 0.0272108843537415 2.23428931043783 0.105191894874088 0.563707417659797 GO:0030291 protein serine/threonine kinase inhibitor activity 2/227 46/18639 0.0434782608695652 3.57000574602567 0.107934772878459 0.563707417659797 GO:0016757 glycosyltransferase activity 6/227 267/18639 0.0224719101123595 1.8451715091818 0.108641368200265 0.563707417659797 GO:0005031 tumor necrosis factor receptor activity 1/227 10/18639 0.1 8.21101321585903 0.115351699689251 0.563707417659797 GO:0005381 iron ion transmembrane transporter activity 1/227 10/18639 0.1 8.21101321585903 0.115351699689251 0.563707417659797 GO:0005528 FK506 binding 1/227 10/18639 0.1 8.21101321585903 0.115351699689251 0.563707417659797 GO:0008140 cAMP response element binding protein binding 1/227 10/18639 0.1 8.21101321585903 0.115351699689251 0.563707417659797 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/227 10/18639 0.1 8.21101321585903 0.115351699689251 0.563707417659797 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/227 10/18639 0.1 8.21101321585903 0.115351699689251 0.563707417659797 GO:0032266 phosphatidylinositol-3-phosphate binding 2/227 48/18639 0.0416666666666667 3.42125550660793 0.115831949994677 0.563707417659797 GO:0042626 ATPase-coupled transmembrane transporter activity 3/227 98/18639 0.0306122448979592 2.51357547424256 0.117570378157327 0.563707417659797 GO:0035254 glutamate receptor binding 2/227 49/18639 0.0408163265306122 3.35143396565675 0.119834331066916 0.563707417659797 GO:0005126 cytokine receptor binding 6/227 275/18639 0.0218181818181818 1.79149379255106 0.120334065516553 0.563707417659797 GO:1901681 sulfur compound binding 6/227 275/18639 0.0218181818181818 1.79149379255106 0.120334065516553 0.563707417659797 GO:0008017 microtubule binding 6/227 276/18639 0.0217391304347826 1.78500287301283 0.121838209214955 0.563707417659797 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/227 11/18639 0.0909090909090909 7.46455746896276 0.126131406821708 0.563707417659797 GO:0001851 complement component C3b binding 1/227 11/18639 0.0909090909090909 7.46455746896276 0.126131406821708 0.563707417659797 GO:0003953 NAD+ nucleosidase activity 1/227 11/18639 0.0909090909090909 7.46455746896276 0.126131406821708 0.563707417659797 GO:0008503 benzodiazepine receptor activity 1/227 11/18639 0.0909090909090909 7.46455746896276 0.126131406821708 0.563707417659797 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/227 11/18639 0.0909090909090909 7.46455746896276 0.126131406821708 0.563707417659797 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/227 11/18639 0.0909090909090909 7.46455746896276 0.126131406821708 0.563707417659797 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/227 11/18639 0.0909090909090909 7.46455746896276 0.126131406821708 0.563707417659797 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/227 11/18639 0.0909090909090909 7.46455746896276 0.126131406821708 0.563707417659797 GO:0032050 clathrin heavy chain binding 1/227 11/18639 0.0909090909090909 7.46455746896276 0.126131406821708 0.563707417659797 GO:0042608 T cell receptor binding 1/227 11/18639 0.0909090909090909 7.46455746896276 0.126131406821708 0.563707417659797 GO:0043522 leucine zipper domain binding 1/227 11/18639 0.0909090909090909 7.46455746896276 0.126131406821708 0.563707417659797 GO:0047676 arachidonate-CoA ligase activity 1/227 11/18639 0.0909090909090909 7.46455746896276 0.126131406821708 0.563707417659797 GO:0050998 nitric-oxide synthase binding 1/227 11/18639 0.0909090909090909 7.46455746896276 0.126131406821708 0.563707417659797 GO:0140537 transcription regulator activator activity 1/227 11/18639 0.0909090909090909 7.46455746896276 0.126131406821708 0.563707417659797 GO:0004864 protein phosphatase inhibitor activity 2/227 53/18639 0.0377358490566038 3.09849555315435 0.136169214351748 0.563707417659797 GO:0016860 intramolecular oxidoreductase activity 2/227 53/18639 0.0377358490566038 3.09849555315435 0.136169214351748 0.563707417659797 GO:0004859 phospholipase inhibitor activity 1/227 12/18639 0.0833333333333333 6.84251101321586 0.136780331593635 0.563707417659797 GO:0004875 complement receptor activity 1/227 12/18639 0.0833333333333333 6.84251101321586 0.136780331593635 0.563707417659797 GO:0005049 nuclear export signal receptor activity 1/227 12/18639 0.0833333333333333 6.84251101321586 0.136780331593635 0.563707417659797 GO:0005095 GTPase inhibitor activity 1/227 12/18639 0.0833333333333333 6.84251101321586 0.136780331593635 0.563707417659797 GO:0005436 sodium:phosphate symporter activity 1/227 12/18639 0.0833333333333333 6.84251101321586 0.136780331593635 0.563707417659797 GO:0005527 macrolide binding 1/227 12/18639 0.0833333333333333 6.84251101321586 0.136780331593635 0.563707417659797 GO:0015368 calcium:monoatomic cation antiporter activity 1/227 12/18639 0.0833333333333333 6.84251101321586 0.136780331593635 0.563707417659797 GO:0017166 vinculin binding 1/227 12/18639 0.0833333333333333 6.84251101321586 0.136780331593635 0.563707417659797 GO:0035251 UDP-glucosyltransferase activity 1/227 12/18639 0.0833333333333333 6.84251101321586 0.136780331593635 0.563707417659797 GO:0035497 cAMP response element binding 1/227 12/18639 0.0833333333333333 6.84251101321586 0.136780331593635 0.563707417659797 GO:0070008 serine-type exopeptidase activity 1/227 12/18639 0.0833333333333333 6.84251101321586 0.136780331593635 0.563707417659797 GO:0097677 STAT family protein binding 1/227 12/18639 0.0833333333333333 6.84251101321586 0.136780331593635 0.563707417659797 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/227 12/18639 0.0833333333333333 6.84251101321586 0.136780331593635 0.563707417659797 GO:0015485 cholesterol binding 2/227 54/18639 0.037037037037037 3.04111600587372 0.140327438729723 0.563707417659797 GO:0050661 NADP binding 2/227 54/18639 0.037037037037037 3.04111600587372 0.140327438729723 0.563707417659797 GO:0030695 GTPase regulator activity 9/227 489/18639 0.0184049079754601 1.51122942623172 0.14412097214963 0.563707417659797 GO:0060589 nucleoside-triphosphatase regulator activity 9/227 490/18639 0.0183673469387755 1.50814528454554 0.145363278189409 0.563707417659797 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/227 13/18639 0.0769230769230769 6.31616401219926 0.14730005375653 0.563707417659797 GO:0005035 death receptor activity 1/227 13/18639 0.0769230769230769 6.31616401219926 0.14730005375653 0.563707417659797 GO:0005542 folic acid binding 1/227 13/18639 0.0769230769230769 6.31616401219926 0.14730005375653 0.563707417659797 GO:0031994 insulin-like growth factor I binding 1/227 13/18639 0.0769230769230769 6.31616401219926 0.14730005375653 0.563707417659797 GO:0035673 oligopeptide transmembrane transporter activity 1/227 13/18639 0.0769230769230769 6.31616401219926 0.14730005375653 0.563707417659797 GO:0043560 insulin receptor substrate binding 1/227 13/18639 0.0769230769230769 6.31616401219926 0.14730005375653 0.563707417659797 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/227 13/18639 0.0769230769230769 6.31616401219926 0.14730005375653 0.563707417659797 GO:0089720 caspase binding 1/227 13/18639 0.0769230769230769 6.31616401219926 0.14730005375653 0.563707417659797 GO:0019212 phosphatase inhibitor activity 2/227 56/18639 0.0357142857142857 2.93250471994965 0.148724114046714 0.563707417659797 GO:0005543 phospholipid binding 9/227 497/18639 0.0181086519114688 1.48690380166461 0.154210901237291 0.563707417659797 GO:0005200 structural constituent of cytoskeleton 3/227 112/18639 0.0267857142857143 2.19937853996224 0.15647598338575 0.563707417659797 GO:0005161 platelet-derived growth factor receptor binding 1/227 14/18639 0.0714285714285714 5.86500943989931 0.157692134063481 0.563707417659797 GO:0005545 1-phosphatidylinositol binding 1/227 14/18639 0.0714285714285714 5.86500943989931 0.157692134063481 0.563707417659797 GO:0032036 myosin heavy chain binding 1/227 14/18639 0.0714285714285714 5.86500943989931 0.157692134063481 0.563707417659797 GO:0043176 amine binding 1/227 14/18639 0.0714285714285714 5.86500943989931 0.157692134063481 0.563707417659797 GO:0044548 S100 protein binding 1/227 14/18639 0.0714285714285714 5.86500943989931 0.157692134063481 0.563707417659797 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 1/227 14/18639 0.0714285714285714 5.86500943989931 0.157692134063481 0.563707417659797 GO:0061665 SUMO ligase activity 1/227 14/18639 0.0714285714285714 5.86500943989931 0.157692134063481 0.563707417659797 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/227 14/18639 0.0714285714285714 5.86500943989931 0.157692134063481 0.563707417659797 GO:0098847 sequence-specific single stranded DNA binding 1/227 14/18639 0.0714285714285714 5.86500943989931 0.157692134063481 0.563707417659797 GO:1990825 sequence-specific mRNA binding 1/227 14/18639 0.0714285714285714 5.86500943989931 0.157692134063481 0.563707417659797 GO:0046982 protein heterodimerization activity 7/227 369/18639 0.018970189701897 1.55764478349629 0.165038910202951 0.563707417659797 GO:0004467 long-chain fatty acid-CoA ligase activity 1/227 15/18639 0.0666666666666667 5.47400881057269 0.167958114496641 0.563707417659797 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/227 15/18639 0.0666666666666667 5.47400881057269 0.167958114496641 0.563707417659797 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/227 15/18639 0.0666666666666667 5.47400881057269 0.167958114496641 0.563707417659797 GO:0005041 low-density lipoprotein particle receptor activity 1/227 15/18639 0.0666666666666667 5.47400881057269 0.167958114496641 0.563707417659797 GO:0015929 hexosaminidase activity 1/227 15/18639 0.0666666666666667 5.47400881057269 0.167958114496641 0.563707417659797 GO:0017081 chloride channel regulator activity 1/227 15/18639 0.0666666666666667 5.47400881057269 0.167958114496641 0.563707417659797 GO:0120283 protein serine/threonine kinase binding 1/227 15/18639 0.0666666666666667 5.47400881057269 0.167958114496641 0.563707417659797 GO:0005319 lipid transporter activity 4/227 178/18639 0.0224719101123595 1.8451715091818 0.172568929658333 0.563707417659797 GO:0022853 active monoatomic ion transmembrane transporter activity 3/227 118/18639 0.0254237288135593 2.08754573284552 0.174232439523096 0.563707417659797 GO:0016853 isomerase activity 4/227 180/18639 0.0222222222222222 1.82466960352423 0.177350065257961 0.563707417659797 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/227 16/18639 0.0625 5.13188325991189 0.178099518491983 0.563707417659797 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/227 16/18639 0.0625 5.13188325991189 0.178099518491983 0.563707417659797 GO:0016722 oxidoreductase activity, acting on metal ions 1/227 16/18639 0.0625 5.13188325991189 0.178099518491983 0.563707417659797 GO:0022858 alanine transmembrane transporter activity 1/227 16/18639 0.0625 5.13188325991189 0.178099518491983 0.563707417659797 GO:0030275 LRR domain binding 1/227 16/18639 0.0625 5.13188325991189 0.178099518491983 0.563707417659797 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/227 16/18639 0.0625 5.13188325991189 0.178099518491983 0.563707417659797 GO:0055102 lipase inhibitor activity 1/227 16/18639 0.0625 5.13188325991189 0.178099518491983 0.563707417659797 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/227 16/18639 0.0625 5.13188325991189 0.178099518491983 0.563707417659797 GO:0005507 copper ion binding 2/227 63/18639 0.0317460317460317 2.60667086217747 0.178826990020366 0.563707417659797 GO:0003697 single-stranded DNA binding 3/227 121/18639 0.0247933884297521 2.03578840062621 0.183315589945745 0.563707417659797 GO:0005092 GDP-dissociation inhibitor activity 1/227 17/18639 0.0588235294117647 4.83000777403472 0.188117851161387 0.563707417659797 GO:0008429 phosphatidylethanolamine binding 1/227 17/18639 0.0588235294117647 4.83000777403472 0.188117851161387 0.563707417659797 GO:0017110 nucleoside diphosphate phosphatase activity 1/227 17/18639 0.0588235294117647 4.83000777403472 0.188117851161387 0.563707417659797 GO:0030169 low-density lipoprotein particle binding 1/227 17/18639 0.0588235294117647 4.83000777403472 0.188117851161387 0.563707417659797 GO:0038191 neuropilin binding 1/227 17/18639 0.0588235294117647 4.83000777403472 0.188117851161387 0.563707417659797 GO:0045236 CXCR chemokine receptor binding 1/227 17/18639 0.0588235294117647 4.83000777403472 0.188117851161387 0.563707417659797 GO:0048038 quinone binding 1/227 17/18639 0.0588235294117647 4.83000777403472 0.188117851161387 0.563707417659797 GO:0051787 misfolded protein binding 1/227 17/18639 0.0588235294117647 4.83000777403472 0.188117851161387 0.563707417659797 GO:0070402 NADPH binding 1/227 17/18639 0.0588235294117647 4.83000777403472 0.188117851161387 0.563707417659797 GO:1901981 phosphatidylinositol phosphate binding 4/227 185/18639 0.0216216216216216 1.77535420883439 0.189495382015272 0.563707417659797 GO:0000900 mRNA regulatory element binding translation repressor activity 1/227 18/18639 0.0555555555555556 4.56167400881057 0.198014599512068 0.563707417659797 GO:0003746 translation elongation factor activity 1/227 18/18639 0.0555555555555556 4.56167400881057 0.198014599512068 0.563707417659797 GO:0004706 JUN kinase kinase kinase activity 1/227 18/18639 0.0555555555555556 4.56167400881057 0.198014599512068 0.563707417659797 GO:0015172 acidic amino acid transmembrane transporter activity 1/227 18/18639 0.0555555555555556 4.56167400881057 0.198014599512068 0.563707417659797 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/227 18/18639 0.0555555555555556 4.56167400881057 0.198014599512068 0.563707417659797 GO:0016854 racemase and epimerase activity 1/227 18/18639 0.0555555555555556 4.56167400881057 0.198014599512068 0.563707417659797 GO:0030228 lipoprotein particle receptor activity 1/227 18/18639 0.0555555555555556 4.56167400881057 0.198014599512068 0.563707417659797 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/227 18/18639 0.0555555555555556 4.56167400881057 0.198014599512068 0.563707417659797 GO:0098641 cadherin binding involved in cell-cell adhesion 1/227 18/18639 0.0555555555555556 4.56167400881057 0.198014599512068 0.563707417659797 GO:0032934 sterol binding 2/227 68/18639 0.0294117647058824 2.41500388701736 0.200852155378955 0.563707417659797 GO:0019902 phosphatase binding 4/227 190/18639 0.0210526315789474 1.72863436123348 0.201897989654683 0.563707417659797 GO:0031490 chromatin DNA binding 3/227 128/18639 0.0234375 1.92445622246696 0.204972661873743 0.563707417659797 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 3/227 128/18639 0.0234375 1.92445622246696 0.204972661873743 0.563707417659797 GO:0003756 protein disulfide isomerase activity 1/227 19/18639 0.0526315789473684 4.3215859030837 0.20779123266339 0.563707417659797 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/227 19/18639 0.0526315789473684 4.3215859030837 0.20779123266339 0.563707417659797 GO:0030506 ankyrin binding 1/227 19/18639 0.0526315789473684 4.3215859030837 0.20779123266339 0.563707417659797 GO:0046527 glucosyltransferase activity 1/227 19/18639 0.0526315789473684 4.3215859030837 0.20779123266339 0.563707417659797 GO:0097001 ceramide binding 1/227 19/18639 0.0526315789473684 4.3215859030837 0.20779123266339 0.563707417659797 GO:0001614 purinergic nucleotide receptor activity 1/227 20/18639 0.05 4.10550660792952 0.217449202061102 0.563707417659797 GO:0001972 retinoic acid binding 1/227 20/18639 0.05 4.10550660792952 0.217449202061102 0.563707417659797 GO:0016004 phospholipase activator activity 1/227 20/18639 0.05 4.10550660792952 0.217449202061102 0.563707417659797 GO:0016502 nucleotide receptor activity 1/227 20/18639 0.05 4.10550660792952 0.217449202061102 0.563707417659797 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/227 20/18639 0.05 4.10550660792952 0.217449202061102 0.563707417659797 GO:0052745 inositol phosphate phosphatase activity 1/227 20/18639 0.05 4.10550660792952 0.217449202061102 0.563707417659797 GO:0005518 collagen binding 2/227 72/18639 0.0277777777777778 2.28083700440529 0.218688340600547 0.563707417659797 GO:0042379 chemokine receptor binding 2/227 72/18639 0.0277777777777778 2.28083700440529 0.218688340600547 0.563707417659797 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/227 21/18639 0.0476190476190476 3.91000629326621 0.226989941689016 0.563707417659797 GO:0001846 opsonin binding 1/227 21/18639 0.0476190476190476 3.91000629326621 0.226989941689016 0.563707417659797 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/227 21/18639 0.0476190476190476 3.91000629326621 0.226989941689016 0.563707417659797 GO:0010314 phosphatidylinositol-5-phosphate binding 1/227 21/18639 0.0476190476190476 3.91000629326621 0.226989941689016 0.563707417659797 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/227 21/18639 0.0476190476190476 3.91000629326621 0.226989941689016 0.563707417659797 GO:0019838 growth factor binding 3/227 136/18639 0.0220588235294118 1.81125291526302 0.230389567665729 0.563707417659797 GO:0003725 double-stranded RNA binding 2/227 75/18639 0.0266666666666667 2.18960352422907 0.232153050786415 0.563707417659797 GO:0044183 protein folding chaperone 2/227 75/18639 0.0266666666666667 2.18960352422907 0.232153050786415 0.563707417659797 GO:0005096 GTPase activator activity 5/227 271/18639 0.018450184501845 1.51494708779687 0.235743836008241 0.563707417659797 GO:0070034 telomerase RNA binding 1/227 22/18639 0.0454545454545455 3.73227873448138 0.236414868278155 0.563707417659797 GO:0017022 myosin binding 2/227 76/18639 0.0263157894736842 2.16079295154185 0.236653434683303 0.563707417659797 GO:0070851 growth factor receptor binding 3/227 139/18639 0.0215827338129496 1.77216112572497 0.240069976208271 0.563707417659797 GO:0140297 DNA-binding transcription factor binding 8/227 488/18639 0.0163934426229508 1.34606774030476 0.245394824043607 0.563707417659797 GO:0005516 calmodulin binding 4/227 207/18639 0.0193236714975845 1.58666922045585 0.245692654339307 0.563707417659797 GO:0005283 amino acid:sodium symporter activity 1/227 23/18639 0.0434782608695652 3.57000574602567 0.245725381513416 0.563707417659797 GO:0016849 phosphorus-oxygen lyase activity 1/227 23/18639 0.0434782608695652 3.57000574602567 0.245725381513416 0.563707417659797 GO:0015370 solute:sodium symporter activity 2/227 79/18639 0.0253164556962025 2.07873752300229 0.2501798642627 0.563707417659797 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/227 24/18639 0.0416666666666667 3.42125550660793 0.254922864237764 0.563707417659797 GO:0005315 phosphate transmembrane transporter activity 1/227 24/18639 0.0416666666666667 3.42125550660793 0.254922864237764 0.563707417659797 GO:0005540 hyaluronic acid binding 1/227 24/18639 0.0416666666666667 3.42125550660793 0.254922864237764 0.563707417659797 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/227 24/18639 0.0416666666666667 3.42125550660793 0.254922864237764 0.563707417659797 GO:0060229 lipase activator activity 1/227 24/18639 0.0416666666666667 3.42125550660793 0.254922864237764 0.563707417659797 GO:0070300 phosphatidic acid binding 1/227 24/18639 0.0416666666666667 3.42125550660793 0.254922864237764 0.563707417659797 GO:0033192 calmodulin-dependent protein phosphatase activity 2/227 81/18639 0.0246913580246914 2.02741067058248 0.259210985268008 0.563707417659797 GO:0140791 histone H2AXS140 phosphatase activity 2/227 81/18639 0.0246913580246914 2.02741067058248 0.259210985268008 0.563707417659797 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 2/227 81/18639 0.0246913580246914 2.02741067058248 0.259210985268008 0.563707417659797 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 2/227 81/18639 0.0246913580246914 2.02741067058248 0.259210985268008 0.563707417659797 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 2/227 81/18639 0.0246913580246914 2.02741067058248 0.259210985268008 0.563707417659797 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 2/227 81/18639 0.0246913580246914 2.02741067058248 0.259210985268008 0.563707417659797 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 2/227 81/18639 0.0246913580246914 2.02741067058248 0.259210985268008 0.563707417659797 GO:1990439 MAP kinase serine/threonine phosphatase activity 2/227 81/18639 0.0246913580246914 2.02741067058248 0.259210985268008 0.563707417659797 GO:0008194 UDP-glycosyltransferase activity 3/227 145/18639 0.0206896551724138 1.69883032052256 0.259624243283007 0.563707417659797 GO:0031267 small GTPase binding 5/227 283/18639 0.0176678445229682 1.45070904873834 0.2630497962249 0.563707417659797 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 2/227 82/18639 0.024390243902439 2.00268615020952 0.263728419444344 0.563707417659797 GO:0033549 MAP kinase phosphatase activity 2/227 82/18639 0.024390243902439 2.00268615020952 0.263728419444344 0.563707417659797 GO:0001848 complement binding 1/227 25/18639 0.04 3.28440528634361 0.264008682653989 0.563707417659797 GO:0005251 delayed rectifier potassium channel activity 1/227 25/18639 0.04 3.28440528634361 0.264008682653989 0.563707417659797 GO:0005537 D-mannose binding 1/227 25/18639 0.04 3.28440528634361 0.264008682653989 0.563707417659797 GO:0008139 nuclear localization sequence binding 1/227 25/18639 0.04 3.28440528634361 0.264008682653989 0.563707417659797 GO:0015645 fatty acid ligase activity 1/227 25/18639 0.04 3.28440528634361 0.264008682653989 0.563707417659797 GO:0015662 P-type ion transporter activity 1/227 25/18639 0.04 3.28440528634361 0.264008682653989 0.563707417659797 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/227 25/18639 0.04 3.28440528634361 0.264008682653989 0.563707417659797 GO:0017025 TBP-class protein binding 1/227 25/18639 0.04 3.28440528634361 0.264008682653989 0.563707417659797 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/227 25/18639 0.04 3.28440528634361 0.264008682653989 0.563707417659797 GO:0019707 protein-cysteine S-acyltransferase activity 1/227 25/18639 0.04 3.28440528634361 0.264008682653989 0.563707417659797 GO:0047617 fatty acyl-CoA hydrolase activity 1/227 25/18639 0.04 3.28440528634361 0.264008682653989 0.563707417659797 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/227 25/18639 0.04 3.28440528634361 0.264008682653989 0.563707417659797 GO:0120515 fatty acid-CoA ligase activity 1/227 25/18639 0.04 3.28440528634361 0.264008682653989 0.563707417659797 GO:0140358 P-type transmembrane transporter activity 1/227 25/18639 0.04 3.28440528634361 0.264008682653989 0.563707417659797 GO:0035091 phosphatidylinositol binding 5/227 284/18639 0.0176056338028169 1.44560091828504 0.265358881247648 0.563707417659797 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 2/227 83/18639 0.0240963855421687 1.97855740141181 0.268246175196084 0.563707417659797 GO:0030165 PDZ domain binding 2/227 83/18639 0.0240963855421687 1.97855740141181 0.268246175196084 0.563707417659797 GO:0019207 kinase regulator activity 5/227 287/18639 0.0174216027874564 1.43049010729251 0.272313663334439 0.563707417659797 GO:0004860 protein kinase inhibitor activity 2/227 84/18639 0.0238095238095238 1.9550031466331 0.272763577625162 0.563707417659797 GO:0017018 myosin phosphatase activity 2/227 84/18639 0.0238095238095238 1.9550031466331 0.272763577625162 0.563707417659797 GO:0004435 phosphatidylinositol phospholipase C activity 1/227 26/18639 0.0384615384615385 3.15808200609963 0.272984186524062 0.563707417659797 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/227 26/18639 0.0384615384615385 3.15808200609963 0.272984186524062 0.563707417659797 GO:0008143 poly(A) binding 1/227 26/18639 0.0384615384615385 3.15808200609963 0.272984186524062 0.563707417659797 GO:0016289 acyl-CoA hydrolase activity 1/227 26/18639 0.0384615384615385 3.15808200609963 0.272984186524062 0.563707417659797 GO:0120014 phospholipid transfer activity 1/227 26/18639 0.0384615384615385 3.15808200609963 0.272984186524062 0.563707417659797 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 2/227 86/18639 0.0232558139534884 1.90953795717652 0.281794703870234 0.56567931844707 GO:0016209 antioxidant activity 2/227 86/18639 0.0232558139534884 1.90953795717652 0.281794703870234 0.56567931844707 GO:0008266 poly(U) RNA binding 1/227 27/18639 0.037037037037037 3.04111600587372 0.28185070936611 0.56567931844707 GO:0015252 proton channel activity 1/227 27/18639 0.037037037037037 3.04111600587372 0.28185070936611 0.56567931844707 GO:0016405 CoA-ligase activity 1/227 27/18639 0.037037037037037 3.04111600587372 0.28185070936611 0.56567931844707 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/227 27/18639 0.037037037037037 3.04111600587372 0.28185070936611 0.56567931844707 GO:0023026 MHC class II protein complex binding 1/227 27/18639 0.037037037037037 3.04111600587372 0.28185070936611 0.56567931844707 GO:0035255 ionotropic glutamate receptor binding 1/227 27/18639 0.037037037037037 3.04111600587372 0.28185070936611 0.56567931844707 GO:0005242 inward rectifier potassium channel activity 1/227 28/18639 0.0357142857142857 2.93250471994965 0.29060956864904 0.567737758045806 GO:0019789 SUMO transferase activity 1/227 28/18639 0.0357142857142857 2.93250471994965 0.29060956864904 0.567737758045806 GO:0046625 sphingolipid binding 1/227 28/18639 0.0357142857142857 2.93250471994965 0.29060956864904 0.567737758045806 GO:0046966 nuclear thyroid hormone receptor binding 1/227 28/18639 0.0357142857142857 2.93250471994965 0.29060956864904 0.567737758045806 GO:0051019 mitogen-activated protein kinase binding 1/227 28/18639 0.0357142857142857 2.93250471994965 0.29060956864904 0.567737758045806 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/227 28/18639 0.0357142857142857 2.93250471994965 0.29060956864904 0.567737758045806 GO:0097718 disordered domain specific binding 1/227 28/18639 0.0357142857142857 2.93250471994965 0.29060956864904 0.567737758045806 GO:0004197 cysteine-type endopeptidase activity 2/227 88/18639 0.0227272727272727 1.86613936724069 0.290816718719268 0.567737758045806 GO:0003785 actin monomer binding 1/227 29/18639 0.0344827586206897 2.8313838675376 0.299262065984845 0.570593005811105 GO:0004181 metallocarboxypeptidase activity 1/227 29/18639 0.0344827586206897 2.8313838675376 0.299262065984845 0.570593005811105 GO:0004629 phospholipase C activity 1/227 29/18639 0.0344827586206897 2.8313838675376 0.299262065984845 0.570593005811105 GO:0005416 amino acid:monoatomic cation symporter activity 1/227 29/18639 0.0344827586206897 2.8313838675376 0.299262065984845 0.570593005811105 GO:0016417 S-acyltransferase activity 1/227 29/18639 0.0344827586206897 2.8313838675376 0.299262065984845 0.570593005811105 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/227 29/18639 0.0344827586206897 2.8313838675376 0.299262065984845 0.570593005811105 GO:0106222 lncRNA binding 1/227 29/18639 0.0344827586206897 2.8313838675376 0.299262065984845 0.570593005811105 GO:0072341 modified amino acid binding 2/227 91/18639 0.021978021978022 1.80461828919979 0.304322149454089 0.577268940151631 GO:0001965 G-protein alpha-subunit binding 1/227 30/18639 0.0333333333333333 2.73700440528634 0.307809487318615 0.577268940151631 GO:0001968 fibronectin binding 1/227 30/18639 0.0333333333333333 2.73700440528634 0.307809487318615 0.577268940151631 GO:0008187 poly-pyrimidine tract binding 1/227 30/18639 0.0333333333333333 2.73700440528634 0.307809487318615 0.577268940151631 GO:0016769 transferase activity, transferring nitrogenous groups 1/227 30/18639 0.0333333333333333 2.73700440528634 0.307809487318615 0.577268940151631 GO:0005178 integrin binding 3/227 161/18639 0.0186335403726708 1.53000246258243 0.312578390442221 0.58203092291742 GO:0005164 tumor necrosis factor receptor binding 1/227 31/18639 0.032258064516129 2.64871394059969 0.316253103116276 0.58203092291742 GO:0016411 acylglycerol O-acyltransferase activity 1/227 31/18639 0.032258064516129 2.64871394059969 0.316253103116276 0.58203092291742 GO:0016878 acid-thiol ligase activity 1/227 31/18639 0.032258064516129 2.64871394059969 0.316253103116276 0.58203092291742 GO:0070273 phosphatidylinositol-4-phosphate binding 1/227 31/18639 0.032258064516129 2.64871394059969 0.316253103116276 0.58203092291742 GO:0005125 cytokine activity 4/227 234/18639 0.0170940170940171 1.40359200271095 0.318724270182276 0.58203092291742 GO:0015081 sodium ion transmembrane transporter activity 3/227 164/18639 0.0182926829268293 1.50201461265714 0.322569989373356 0.58203092291742 GO:0022804 active transmembrane transporter activity 7/227 457/18639 0.0153172866520788 1.2577044313132 0.322997219495956 0.58203092291742 GO:0030515 snoRNA binding 1/227 32/18639 0.03125 2.56594162995595 0.3245941685501 0.58203092291742 GO:0051059 NF-kappaB binding 1/227 32/18639 0.03125 2.56594162995595 0.3245941685501 0.58203092291742 GO:0070717 poly-purine tract binding 1/227 32/18639 0.03125 2.56594162995595 0.3245941685501 0.58203092291742 GO:0071813 lipoprotein particle binding 1/227 32/18639 0.03125 2.56594162995595 0.3245941685501 0.58203092291742 GO:0071814 protein-lipid complex binding 1/227 32/18639 0.03125 2.56594162995595 0.3245941685501 0.58203092291742 GO:0140142 nucleocytoplasmic carrier activity 1/227 32/18639 0.03125 2.56594162995595 0.3245941685501 0.58203092291742 GO:0015631 tubulin binding 6/227 385/18639 0.0155844155844156 1.27963842325076 0.328685959717918 0.586670063305735 GO:0015399 primary active transmembrane transporter activity 3/227 166/18639 0.0180722891566265 1.48391805105886 0.32923267538661 0.586670063305735 GO:0030594 neurotransmitter receptor activity 2/227 97/18639 0.0206185567010309 1.69299241564104 0.331178907833634 0.588305389070928 GO:0016874 ligase activity 3/227 167/18639 0.0179640718562874 1.47503231422617 0.332563750049163 0.58893642423567 GO:0005249 voltage-gated potassium channel activity 2/227 98/18639 0.0204081632653061 1.67571698282837 0.335629085535224 0.591173998974277 GO:0005201 extracellular matrix structural constituent 3/227 168/18639 0.0178571428571429 1.46625235997483 0.335894317599021 0.591173998974277 GO:0051020 GTPase binding 5/227 315/18639 0.0158730158730159 1.30333543108873 0.338722081324004 0.594322179501013 GO:0008376 acetylgalactosaminyltransferase activity 1/227 34/18639 0.0294117647058824 2.41500388701736 0.340973593644595 0.594624681599721 GO:0015020 glucuronosyltransferase activity 1/227 34/18639 0.0294117647058824 2.41500388701736 0.340973593644595 0.594624681599721 GO:0043130 ubiquitin binding 2/227 100/18639 0.02 1.64220264317181 0.344502945219439 0.598953448831366 GO:0005343 organic acid:sodium symporter activity 1/227 35/18639 0.0285714285714286 2.34600377595972 0.34901438882023 0.604958273955065 GO:0033218 amide binding 4/227 247/18639 0.0161943319838057 1.32971873941037 0.354594262412703 0.60901139972122 GO:0016409 palmitoyltransferase activity 1/227 36/18639 0.0277777777777778 2.28083700440529 0.356957505017704 0.60901139972122 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/227 36/18639 0.0277777777777778 2.28083700440529 0.356957505017704 0.60901139972122 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/227 36/18639 0.0277777777777778 2.28083700440529 0.356957505017704 0.60901139972122 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/227 36/18639 0.0277777777777778 2.28083700440529 0.356957505017704 0.60901139972122 GO:0004722 protein serine/threonine phosphatase activity 2/227 103/18639 0.0194174757281553 1.59437149822505 0.357740962074004 0.60901139972122 GO:0042277 peptide binding 4/227 249/18639 0.0160642570281124 1.31903826760788 0.360121466799456 0.611244744834685 GO:0023023 MHC protein complex binding 1/227 37/18639 0.027027027027027 2.21919276104298 0.36480412364701 0.615539701256902 GO:0043394 proteoglycan binding 1/227 37/18639 0.027027027027027 2.21919276104298 0.36480412364701 0.615539701256902 GO:0042887 amide transmembrane transporter activity 1/227 38/18639 0.0263157894736842 2.16079295154185 0.372555411891937 0.626769692947611 GO:0019887 protein kinase regulator activity 4/227 255/18639 0.0156862745098039 1.28800207307593 0.376693517702844 0.631872997437029 GO:0005496 steroid binding 2/227 108/18639 0.0185185185185185 1.52055800293686 0.379583352622306 0.63221384618522 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/227 39/18639 0.0256410256410256 2.10538800406642 0.380212522880622 0.63221384618522 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/227 39/18639 0.0256410256410256 2.10538800406642 0.380212522880622 0.63221384618522 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/227 40/18639 0.025 2.05275330396476 0.387776595854068 0.635062608489537 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/227 40/18639 0.025 2.05275330396476 0.387776595854068 0.635062608489537 GO:0061791 GTPase motor activity 1/227 40/18639 0.025 2.05275330396476 0.387776595854068 0.635062608489537 GO:0071949 FAD binding 1/227 40/18639 0.025 2.05275330396476 0.387776595854068 0.635062608489537 GO:1990606 membrane scission GTPase motor activity 1/227 40/18639 0.025 2.05275330396476 0.387776595854068 0.635062608489537 GO:0001216 DNA-binding transcription activator activity 7/227 491/18639 0.0142566191446029 1.17061288209803 0.390346681409551 0.635062608489537 GO:1902936 phosphatidylinositol bisphosphate binding 2/227 111/18639 0.018018018018018 1.47946184069532 0.39254001682364 0.635062608489537 GO:0008227 G protein-coupled amine receptor activity 1/227 41/18639 0.024390243902439 2.00268615020952 0.395248756332649 0.635062608489537 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/227 41/18639 0.024390243902439 2.00268615020952 0.395248756332649 0.635062608489537 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/227 41/18639 0.024390243902439 2.00268615020952 0.395248756332649 0.635062608489537 GO:0042169 SH2 domain binding 1/227 41/18639 0.024390243902439 2.00268615020952 0.395248756332649 0.635062608489537 GO:0140828 metal cation:monoatomic cation antiporter activity 1/227 41/18639 0.024390243902439 2.00268615020952 0.395248756332649 0.635062608489537 GO:0005261 monoatomic cation channel activity 5/227 341/18639 0.0146627565982405 1.20396088209077 0.401449078222979 0.641516508391416 GO:0016859 cis-trans isomerase activity 1/227 42/18639 0.0238095238095238 1.9550031466331 0.402630116280626 0.641516508391416 GO:0035198 miRNA binding 1/227 42/18639 0.0238095238095238 1.9550031466331 0.402630116280626 0.641516508391416 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/227 43/18639 0.0232558139534884 1.90953795717652 0.409921774268705 0.64772169856823 GO:0008200 ion channel inhibitor activity 1/227 43/18639 0.0232558139534884 1.90953795717652 0.409921774268705 0.64772169856823 GO:0008375 acetylglucosaminyltransferase activity 1/227 43/18639 0.0232558139534884 1.90953795717652 0.409921774268705 0.64772169856823 GO:0015294 solute:monoatomic cation symporter activity 2/227 116/18639 0.0172413793103448 1.4156919337688 0.413858182866094 0.652140166940511 GO:0001046 core promoter sequence-specific DNA binding 1/227 44/18639 0.0227272727272727 1.86613936724069 0.417124815634644 0.65368601244662 GO:0016248 channel inhibitor activity 1/227 44/18639 0.0227272727272727 1.86613936724069 0.417124815634644 0.65368601244662 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 5/227 349/18639 0.0143266475644699 1.17636292490817 0.420689174568061 0.657470513259373 GO:0008009 chemokine activity 1/227 45/18639 0.0222222222222222 1.82466960352423 0.424240312641954 0.657629969732244 GO:0046915 transition metal ion transmembrane transporter activity 1/227 45/18639 0.0222222222222222 1.82466960352423 0.424240312641954 0.657629969732244 GO:0141110 transporter inhibitor activity 1/227 45/18639 0.0222222222222222 1.82466960352423 0.424240312641954 0.657629969732244 GO:0016791 phosphatase activity 4/227 273/18639 0.0146520146520147 1.20307885946652 0.426081943575728 0.657829476512512 GO:0032182 ubiquitin-like protein binding 2/227 120/18639 0.0166666666666667 1.36850220264317 0.430643447015198 0.657829476512512 GO:0016758 hexosyltransferase activity 3/227 197/18639 0.0152284263959391 1.25040810393792 0.431264885826341 0.657829476512512 GO:0004180 carboxypeptidase activity 1/227 46/18639 0.0217391304347826 1.78500287301283 0.431269324636699 0.657829476512512 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/227 46/18639 0.0217391304347826 1.78500287301283 0.431269324636699 0.657829476512512 GO:0030276 clathrin binding 1/227 46/18639 0.0217391304347826 1.78500287301283 0.431269324636699 0.657829476512512 GO:0004674 protein serine/threonine kinase activity 6/227 433/18639 0.0138568129330254 1.13778474122758 0.432721376189399 0.658288902075362 GO:0051082 unfolded protein binding 2/227 121/18639 0.0165289256198347 1.35719226708414 0.434800217722247 0.659696882061341 GO:0043495 protein-membrane adaptor activity 1/227 47/18639 0.0212765957446809 1.74702408848064 0.438212898202421 0.663115814211071 GO:0030246 carbohydrate binding 4/227 280/18639 0.0142857142857143 1.17300188797986 0.445047878254237 0.668192185047675 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/227 48/18639 0.0208333333333333 1.71062775330396 0.445072067313224 0.668192185047675 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/227 48/18639 0.0208333333333333 1.71062775330396 0.445072067313224 0.668192185047675 GO:0005267 potassium channel activity 2/227 124/18639 0.0161290322580645 1.32435697029984 0.44717193127658 0.669587289764931 GO:0106310 protein serine kinase activity 5/227 361/18639 0.0138504155124654 1.13725944817992 0.449340096588908 0.67107711553226 GO:0001222 transcription corepressor binding 1/227 49/18639 0.0204081632653061 1.67571698282837 0.451847853485022 0.671150954746757 GO:0016763 pentosyltransferase activity 1/227 49/18639 0.0204081632653061 1.67571698282837 0.451847853485022 0.671150954746757 GO:0003714 transcription corepressor activity 3/227 204/18639 0.0147058823529412 1.20750194350868 0.453632377580026 0.671150954746757 GO:0042578 phosphoric ester hydrolase activity 5/227 363/18639 0.0137741046831956 1.13099355590345 0.45408290120104 0.671150954746757 GO:0032813 tumor necrosis factor receptor superfamily binding 1/227 50/18639 0.02 1.64220264317181 0.458541265924984 0.674256051694321 GO:0048020 CCR chemokine receptor binding 1/227 50/18639 0.02 1.64220264317181 0.458541265924984 0.674256051694321 GO:0015291 secondary active transmembrane transporter activity 4/227 287/18639 0.0139372822299652 1.14439208583401 0.463822601917498 0.675298701930202 GO:0005216 monoatomic ion channel activity 6/227 448/18639 0.0133928571428571 1.09968926998112 0.464952875983535 0.675298701930202 GO:0005010 insulin-like growth factor receptor activity 1/227 51/18639 0.0196078431372549 1.61000259134491 0.465153301679195 0.675298701930202 GO:0005048 signal sequence binding 1/227 51/18639 0.0196078431372549 1.61000259134491 0.465153301679195 0.675298701930202 GO:0016830 carbon-carbon lyase activity 1/227 51/18639 0.0196078431372549 1.61000259134491 0.465153301679195 0.675298701930202 GO:0016798 hydrolase activity, acting on glycosyl bonds 2/227 130/18639 0.0153846153846154 1.26323280243985 0.471453337018324 0.681322699457907 GO:0005080 protein kinase C binding 1/227 52/18639 0.0192307692307692 1.57904100304981 0.471684945778551 0.681322699457907 GO:0005262 calcium channel activity 2/227 131/18639 0.0152671755725191 1.25358980394794 0.475438203149001 0.682031077384105 GO:0005246 calcium channel regulator activity 1/227 53/18639 0.0188679245283019 1.54924777657718 0.478137171382912 0.682031077384105 GO:0005544 calcium-dependent phospholipid binding 1/227 53/18639 0.0188679245283019 1.54924777657718 0.478137171382912 0.682031077384105 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/227 53/18639 0.0188679245283019 1.54924777657718 0.478137171382912 0.682031077384105 GO:0140296 general transcription initiation factor binding 1/227 53/18639 0.0188679245283019 1.54924777657718 0.478137171382912 0.682031077384105 GO:0005179 hormone activity 2/227 132/18639 0.0151515151515152 1.24409291149379 0.479404905813214 0.682138323694423 GO:0051287 NAD binding 1/227 54/18639 0.0185185185185185 1.52055800293686 0.484510939923539 0.685990736723426 GO:0140463 chromatin-protein adaptor activity 1/227 54/18639 0.0185185185185185 1.52055800293686 0.484510939923539 0.685990736723426 GO:0005525 GTP binding 5/227 378/18639 0.0132275132275132 1.08611285924061 0.48927136839258 0.688092448802605 GO:0001664 G protein-coupled receptor binding 4/227 297/18639 0.0134680134680135 1.10586036577226 0.49024709250681 0.688092448802605 GO:0008374 O-acyltransferase activity 1/227 55/18639 0.0181818181818182 1.49291149379255 0.490807201243816 0.688092448802605 GO:0098632 cell-cell adhesion mediator activity 1/227 55/18639 0.0181818181818182 1.49291149379255 0.490807201243816 0.688092448802605 GO:0140789 histone phosphatase activity 2/227 136/18639 0.0147058823529412 1.20750194350868 0.495087177019225 0.692395758569675 GO:0016504 peptidase activator activity 1/227 57/18639 0.0175438596491228 1.44052863436123 0.503170944490147 0.701984829874059 GO:0061980 regulatory RNA binding 1/227 58/18639 0.0172413793103448 1.4156919337688 0.509240269406773 0.706086665054933 GO:0001786 phosphatidylserine binding 1/227 59/18639 0.0169491525423729 1.39169715523034 0.515235773354066 0.706086665054933 GO:0031593 polyubiquitin modification-dependent protein binding 1/227 59/18639 0.0169491525423729 1.39169715523034 0.515235773354066 0.706086665054933 GO:0070063 RNA polymerase binding 1/227 59/18639 0.0169491525423729 1.39169715523034 0.515235773354066 0.706086665054933 GO:0020037 heme binding 2/227 142/18639 0.0140845070422535 1.15648073462803 0.518042976526438 0.706086665054933 GO:0001098 basal transcription machinery binding 1/227 60/18639 0.0166666666666667 1.36850220264317 0.521158350288869 0.706086665054933 GO:0001099 basal RNA polymerase II transcription machinery binding 1/227 60/18639 0.0166666666666667 1.36850220264317 0.521158350288869 0.706086665054933 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/227 60/18639 0.0166666666666667 1.36850220264317 0.521158350288869 0.706086665054933 GO:0022843 voltage-gated monoatomic cation channel activity 2/227 143/18639 0.013986013986014 1.1483934567635 0.521801309742414 0.706086665054933 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 3/227 229/18639 0.0131004366812227 1.07567858723044 0.530217045333043 0.706086665054933 GO:0015179 L-amino acid transmembrane transporter activity 1/227 62/18639 0.0161290322580645 1.32435697029984 0.532788245187233 0.706086665054933 GO:0015293 symporter activity 2/227 146/18639 0.0136986301369863 1.12479633093959 0.532958539575543 0.706086665054933 GO:0005085 guanyl-nucleotide exchange factor activity 3/227 230/18639 0.0130434782608696 1.0710017238077 0.53315728637634 0.706086665054933 GO:0019001 guanyl nucleotide binding 5/227 400/18639 0.0125 1.02637665198238 0.539326646194737 0.706086665054933 GO:0032561 guanyl ribonucleotide binding 5/227 400/18639 0.0125 1.02637665198238 0.539326646194737 0.706086665054933 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 6/227 484/18639 0.012396694214876 1.0178942003131 0.540038792340772 0.706086665054933 GO:0019842 vitamin binding 2/227 150/18639 0.0133333333333333 1.09480176211454 0.547557286101681 0.706086665054933 GO:0038024 cargo receptor activity 1/227 65/18639 0.0153846153846154 1.26323280243985 0.549707870999708 0.706086665054933 GO:0160215 deacylase activity 1/227 65/18639 0.0153846153846154 1.26323280243985 0.549707870999708 0.706086665054933 GO:0000510 H3-H4 histone complex chaperone activity 2/227 151/18639 0.0132450331125828 1.08755141931908 0.551156984422198 0.706086665054933 GO:0140584 chromatin extrusion motor activity 2/227 151/18639 0.0132450331125828 1.08755141931908 0.551156984422198 0.706086665054933 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 2/227 151/18639 0.0132450331125828 1.08755141931908 0.551156984422198 0.706086665054933 GO:0140849 ATP-dependent H2AZ histone chaperone activity 2/227 151/18639 0.0132450331125828 1.08755141931908 0.551156984422198 0.706086665054933 GO:0015616 DNA translocase activity 2/227 152/18639 0.0131578947368421 1.08039647577093 0.554736580143591 0.706086665054933 GO:0046906 tetrapyrrole binding 2/227 152/18639 0.0131578947368421 1.08039647577093 0.554736580143591 0.706086665054933 GO:0140674 ATP-dependent histone chaperone activity 2/227 152/18639 0.0131578947368421 1.08039647577093 0.554736580143591 0.706086665054933 GO:0008235 metalloexopeptidase activity 1/227 66/18639 0.0151515151515152 1.24409291149379 0.555211064349716 0.706086665054933 GO:0061775 cohesin loader activity 2/227 153/18639 0.0130718954248366 1.07333506089661 0.558296027041032 0.706086665054933 GO:0005506 iron ion binding 2/227 154/18639 0.012987012987013 1.06636535270897 0.561835282974579 0.706086665054933 GO:0003712 transcription coregulator activity 6/227 495/18639 0.0121212121212121 0.995274329195034 0.562096690103679 0.706086665054933 GO:0005548 phospholipid transporter activity 1/227 68/18639 0.0147058823529412 1.20750194350868 0.56601737042796 0.706086665054933 GO:0030145 manganese ion binding 1/227 68/18639 0.0147058823529412 1.20750194350868 0.56601737042796 0.706086665054933 GO:0140223 general transcription initiation factor activity 1/227 68/18639 0.0147058823529412 1.20750194350868 0.56601737042796 0.706086665054933 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 3/227 243/18639 0.0123456790123457 1.01370533529124 0.57041726522773 0.706086665054933 GO:0008080 N-acetyltransferase activity 1/227 69/18639 0.0144927536231884 1.19000191534189 0.57132209590924 0.706086665054933 GO:0140658 ATP-dependent chromatin remodeler activity 2/227 158/18639 0.0126582278481013 1.03936876150114 0.575789692146151 0.706086665054933 GO:0004676 3-phosphoinositide-dependent protein kinase activity 3/227 245/18639 0.0122448979591837 1.00543018969702 0.575985645907412 0.706086665054933 GO:0004711 ribosomal protein S6 kinase activity 3/227 245/18639 0.0122448979591837 1.00543018969702 0.575985645907412 0.706086665054933 GO:0035175 histone H3S10 kinase activity 3/227 245/18639 0.0122448979591837 1.00543018969702 0.575985645907412 0.706086665054933 GO:0035979 histone H2AXS139 kinase activity 3/227 245/18639 0.0122448979591837 1.00543018969702 0.575985645907412 0.706086665054933 GO:0044022 histone H3S28 kinase activity 3/227 245/18639 0.0122448979591837 1.00543018969702 0.575985645907412 0.706086665054933 GO:0044023 histone H4S1 kinase activity 3/227 245/18639 0.0122448979591837 1.00543018969702 0.575985645907412 0.706086665054933 GO:0044024 histone H2AS1 kinase activity 3/227 245/18639 0.0122448979591837 1.00543018969702 0.575985645907412 0.706086665054933 GO:0044025 histone H2BS14 kinase activity 3/227 245/18639 0.0122448979591837 1.00543018969702 0.575985645907412 0.706086665054933 GO:0072354 histone H3T3 kinase activity 3/227 245/18639 0.0122448979591837 1.00543018969702 0.575985645907412 0.706086665054933 GO:0072371 histone H2AS121 kinase activity 3/227 245/18639 0.0122448979591837 1.00543018969702 0.575985645907412 0.706086665054933 GO:0072518 Rho-dependent protein serine/threonine kinase activity 3/227 245/18639 0.0122448979591837 1.00543018969702 0.575985645907412 0.706086665054933 GO:0140823 histone H2BS36 kinase activity 3/227 245/18639 0.0122448979591837 1.00543018969702 0.575985645907412 0.706086665054933 GO:0140855 histone H3S57 kinase activity 3/227 245/18639 0.0122448979591837 1.00543018969702 0.575985645907412 0.706086665054933 GO:0140995 histone H2A kinase activity 3/227 245/18639 0.0122448979591837 1.00543018969702 0.575985645907412 0.706086665054933 GO:0140997 histone H4 kinase activity 3/227 245/18639 0.0122448979591837 1.00543018969702 0.575985645907412 0.706086665054933 GO:0140998 histone H2B kinase activity 3/227 245/18639 0.0122448979591837 1.00543018969702 0.575985645907412 0.706086665054933 GO:1990244 histone H2AT120 kinase activity 3/227 245/18639 0.0122448979591837 1.00543018969702 0.575985645907412 0.706086665054933 GO:0016887 ATP hydrolysis activity 5/227 417/18639 0.0119904076738609 0.984533958736095 0.576418540719796 0.706086665054933 GO:0097110 scaffold protein binding 1/227 70/18639 0.0142857142857143 1.17300188797986 0.576562261995864 0.706086665054933 GO:0004677 DNA-dependent protein kinase activity 3/227 246/18639 0.0121951219512195 1.00134307510476 0.578752991183459 0.706086665054933 GO:0140857 histone H3T45 kinase activity 3/227 246/18639 0.0121951219512195 1.00134307510476 0.578752991183459 0.706086665054933 GO:0035402 histone H3T11 kinase activity 3/227 247/18639 0.0121457489878543 0.997289054557777 0.581509041127361 0.706086665054933 GO:0035403 histone H3T6 kinase activity 3/227 247/18639 0.0121457489878543 0.997289054557777 0.581509041127361 0.706086665054933 GO:0042393 histone binding 3/227 247/18639 0.0121457489878543 0.997289054557777 0.581509041127361 0.706086665054933 GO:0003689 DNA clamp loader activity 2/227 160/18639 0.0125 1.02637665198238 0.582644940394979 0.706086665054933 GO:0015079 potassium ion transmembrane transporter activity 2/227 160/18639 0.0125 1.02637665198238 0.582644940394979 0.706086665054933 GO:0004679 AMP-activated protein kinase activity 3/227 248/18639 0.0120967741935484 0.993267727724883 0.584253748919361 0.706539417297832 GO:0140104 molecular carrier activity 3/227 249/18639 0.0120481927710843 0.989278700705907 0.586987069433019 0.708347265222968 GO:0008083 growth factor activity 2/227 162/18639 0.0123456790123457 1.01370533529124 0.589418675726621 0.70978417371711 GO:0004521 RNA endonuclease activity 1/227 73/18639 0.0136986301369863 1.12479633093959 0.59190317945781 0.709787460481903 GO:0043539 protein serine/threonine kinase activator activity 1/227 73/18639 0.0136986301369863 1.12479633093959 0.59190317945781 0.709787460481903 GO:0140713 histone chaperone activity 2/227 164/18639 0.0121951219512195 1.00134307510476 0.596110810175293 0.712782260231897 GO:0048029 monosaccharide binding 1/227 74/18639 0.0135135135135135 1.10959638052149 0.596892836802585 0.712782260231897 GO:0015103 inorganic anion transmembrane transporter activity 2/227 165/18639 0.0121212121212121 0.995274329195034 0.599426263809128 0.714316297705877 GO:0019003 GDP binding 1/227 75/18639 0.0133333333333333 1.09480176211454 0.60182175282983 0.715679922284123 GO:0098631 cell adhesion mediator activity 1/227 76/18639 0.0131578947368421 1.08039647577093 0.60669066373845 0.719973152818244 GO:0019199 transmembrane receptor protein kinase activity 1/227 78/18639 0.0128205128205128 1.05269400203321 0.616251370683541 0.729804935881957 GO:0003730 mRNA 3'-UTR binding 3/227 262/18639 0.0114503816793893 0.940192352960958 0.621466417619656 0.734460311732321 GO:0005244 voltage-gated monoatomic ion channel activity 2/227 173/18639 0.0115606936416185 0.949250082758269 0.625215765179996 0.737132568275286 GO:0003823 antigen binding 2/227 174/18639 0.0114942528735632 0.943794622512532 0.628347882082572 0.737132568275286 GO:0003779 actin binding 5/227 443/18639 0.0112866817155756 0.926750927297859 0.629972932648309 0.737132568275286 GO:0015101 organic cation transmembrane transporter activity 1/227 81/18639 0.0123456790123457 1.01370533529124 0.630160292544272 0.737132568275286 GO:0004721 phosphoprotein phosphatase activity 2/227 175/18639 0.0114285714285714 0.938401510383889 0.631459717578479 0.737132568275286 GO:0022832 voltage-gated channel activity 2/227 175/18639 0.0114285714285714 0.938401510383889 0.631459717578479 0.737132568275286 GO:0001540 amyloid-beta binding 1/227 83/18639 0.0120481927710843 0.989278700705907 0.639152898532303 0.741572937039507 GO:0005254 chloride channel activity 1/227 83/18639 0.0120481927710843 0.989278700705907 0.639152898532303 0.741572937039507 GO:0008135 translation factor activity, RNA binding 1/227 83/18639 0.0120481927710843 0.989278700705907 0.639152898532303 0.741572937039507 GO:0180051 translation factor activity 1/227 84/18639 0.0119047619047619 0.977501573316551 0.643567227699858 0.745183105757731 GO:0050660 flavin adenine dinucleotide binding 1/227 86/18639 0.0116279069767442 0.954768978588259 0.652235238390176 0.75369405325087 GO:0008081 phosphoric diester hydrolase activity 1/227 87/18639 0.0114942528735632 0.943794622512532 0.65649021606955 0.757081458854401 GO:0008237 metallopeptidase activity 2/227 184/18639 0.0108695652173913 0.892501436506416 0.658558797535236 0.757938897766911 GO:0016651 oxidoreductase activity, acting on NAD(P)H 1/227 88/18639 0.0113636363636364 0.933069683620344 0.660693359717255 0.758237787901005 GO:0015078 proton transmembrane transporter activity 2/227 185/18639 0.0108108108108108 0.887677104417193 0.661469678605947 0.758237787901005 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/227 89/18639 0.0112359550561798 0.922585754590902 0.664845298014068 0.759064891145802 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/227 89/18639 0.0112359550561798 0.922585754590902 0.664845298014068 0.759064891145802 GO:0008234 cysteine-type peptidase activity 2/227 187/18639 0.0106951871657754 0.878183231642677 0.667231899278444 0.760272203958705 GO:0140793 histone H2AXY142 phosphatase activity 1/227 90/18639 0.0111111111111111 0.912334801762115 0.668946652049152 0.760491409775113 GO:0140597 protein carrier chaperone 2/227 188/18639 0.0106382978723404 0.873512044240322 0.670083340081568 0.760491409775113 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/227 91/18639 0.010989010989011 0.902309144599894 0.672998035411319 0.762286883673811 GO:0052689 carboxylic ester hydrolase activity 1/227 92/18639 0.0108695652173913 0.892501436506416 0.67700005427921 0.765304409185194 GO:0051213 dioxygenase activity 1/227 93/18639 0.010752688172043 0.882904646866563 0.680953307510386 0.76674270058256 GO:0051219 phosphoprotein binding 1/227 93/18639 0.010752688172043 0.882904646866563 0.680953307510386 0.76674270058256 GO:0016410 N-acyltransferase activity 1/227 94/18639 0.0106382978723404 0.873512044240322 0.684858386729363 0.768115680802344 GO:0042562 hormone binding 1/227 94/18639 0.0106382978723404 0.873512044240322 0.684858386729363 0.768115680802344 GO:0004867 serine-type endopeptidase inhibitor activity 1/227 95/18639 0.0105263157894737 0.86431718061674 0.688715876414584 0.770930491798712 GO:0016407 acetyltransferase activity 1/227 96/18639 0.0104166666666667 0.855313876651982 0.692526353984358 0.7736817860919 GO:0004725 protein tyrosine phosphatase activity 1/227 98/18639 0.0102040816326531 0.837858491414187 0.70000854765853 0.780516353334657 GO:0016829 lyase activity 2/227 200/18639 0.01 0.821101321585903 0.702780043765963 0.782082072050838 GO:0008238 exopeptidase activity 1/227 102/18639 0.00980392156862745 0.805001295672454 0.714433432010885 0.791968843236872 GO:0015171 amino acid transmembrane transporter activity 1/227 102/18639 0.00980392156862745 0.805001295672454 0.714433432010885 0.791968843236872 GO:0005253 monoatomic anion channel activity 1/227 103/18639 0.00970873786407767 0.797185749112527 0.717930417010266 0.794305993287954 GO:0008094 ATP-dependent activity, acting on DNA 2/227 210/18639 0.00952380952380952 0.782001258653241 0.727938174740845 0.802527698262517 GO:0008013 beta-catenin binding 1/227 106/18639 0.00943396226415094 0.774623888288588 0.728167614332599 0.802527698262517 GO:0004175 endopeptidase activity 4/227 405/18639 0.00987654320987654 0.810964268232991 0.730113936354913 0.803125329990404 GO:0004620 phospholipase activity 1/227 109/18639 0.00917431192660551 0.753303964757709 0.7380348488162 0.810280102731029 GO:0004222 metalloendopeptidase activity 1/227 110/18639 0.00909090909090909 0.746455746896275 0.741244027948349 0.812244413767156 GO:0043022 ribosome binding 1/227 112/18639 0.00892857142857143 0.733126179987413 0.747545433550544 0.817583151034247 GO:0001221 transcription coregulator binding 1/227 115/18639 0.00869565217391304 0.714001149205133 0.756712204607128 0.824455963876719 GO:0017124 SH3 domain binding 1/227 115/18639 0.00869565217391304 0.714001149205133 0.756712204607128 0.824455963876719 GO:0009055 electron transfer activity 1/227 116/18639 0.00862068965517241 0.707845966884399 0.759693543926615 0.826130621912593 GO:1990782 protein tyrosine kinase binding 1/227 117/18639 0.00854700854700855 0.701796001355473 0.76263850778391 0.827759442983674 GO:0004540 RNA nuclease activity 1/227 121/18639 0.00826446280991736 0.678596133542069 0.774063366388587 0.836983450991062 GO:0015108 chloride transmembrane transporter activity 1/227 121/18639 0.00826446280991736 0.678596133542069 0.774063366388587 0.836983450991062 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 1/227 122/18639 0.00819672131147541 0.67303387015238 0.776832975192442 0.838393324169956 GO:0004519 endonuclease activity 1/227 127/18639 0.0078740157480315 0.646536473689687 0.790182114126835 0.849594303158928 GO:0042826 histone deacetylase binding 1/227 127/18639 0.0078740157480315 0.646536473689687 0.790182114126835 0.849594303158928 GO:0035591 signaling adaptor activity 1/227 129/18639 0.00775193798449612 0.636512652392173 0.79529640885086 0.853488829010679 GO:0016298 lipase activity 1/227 130/18639 0.00769230769230769 0.631616401219925 0.797806820260415 0.854579590241493 GO:0051087 protein-folding chaperone binding 1/227 134/18639 0.00746268656716418 0.612762180287987 0.807545641671392 0.862693670733177 GO:0141003 histone H2AX kinase activity 3/227 354/18639 0.00847457627118644 0.695848577615172 0.808565033788925 0.862693670733177 GO:0015297 antiporter activity 1/227 135/18639 0.00740740740740741 0.608223201174743 0.809906470600902 0.862693670733177 GO:0099094 ligand-gated monoatomic cation channel activity 1/227 136/18639 0.00735294117647059 0.603750971754341 0.812238465368174 0.862808729009784 GO:0140996 histone H3 kinase activity 3/227 357/18639 0.00840336134453781 0.690001110576389 0.813080911285045 0.862808729009784 GO:0016922 nuclear receptor binding 1/227 137/18639 0.0072992700729927 0.599344030354674 0.814541976602105 0.862808729009784 GO:0035173 histone kinase activity 3/227 360/18639 0.00833333333333333 0.684251101321586 0.817506792424604 0.862808729009784 GO:0030295 protein kinase activator activity 1/227 139/18639 0.00719424460431655 0.590720375241657 0.819064929811736 0.862808729009784 GO:0140767 enzyme-substrate adaptor activity 1/227 139/18639 0.00719424460431655 0.590720375241657 0.819064929811736 0.862808729009784 GO:0004713 protein tyrosine kinase activity 1/227 140/18639 0.00714285714285714 0.586500943989931 0.821285052024316 0.863557076760862 GO:0019209 kinase activator activity 1/227 148/18639 0.00675675675675676 0.554798190260745 0.83809681821771 0.878474301276869 GO:0019787 ubiquitin-like protein transferase activity 4/227 479/18639 0.00835073068893528 0.685679600489272 0.838543651218829 0.878474301276869 GO:0008509 monoatomic anion transmembrane transporter activity 1/227 149/18639 0.00671140939597315 0.55107471247376 0.8400843809382 0.878479462333913 GO:0003774 cytoskeletal motor activity 1/227 153/18639 0.0065359477124183 0.536667530448303 0.847794634065582 0.884924326068454 GO:0001217 DNA-binding transcription repressor activity 2/227 278/18639 0.00719424460431655 0.590720375241657 0.855233252839983 0.891062696948034 GO:0016755 aminoacyltransferase activity 4/227 496/18639 0.00806451612903226 0.662178485149922 0.857563606624795 0.891866150889787 GO:0140030 modification-dependent protein binding 1/227 173/18639 0.00578034682080925 0.474625041379135 0.881134662184332 0.914716926986276 GO:0043021 ribonucleoprotein complex binding 1/227 177/18639 0.00564971751412429 0.463899051743448 0.886873007645055 0.919006087632194 GO:0015276 ligand-gated monoatomic ion channel activity 1/227 186/18639 0.00537634408602151 0.441452323433281 0.898795718786735 0.926788966470517 GO:0022834 ligand-gated channel activity 1/227 188/18639 0.00531914893617021 0.436756022120161 0.901270403983294 0.926788966470517 GO:0046943 carboxylic acid transmembrane transporter activity 1/227 188/18639 0.00531914893617021 0.436756022120161 0.901270403983294 0.926788966470517 GO:0022836 gated channel activity 2/227 318/18639 0.00628930817610063 0.516415925525725 0.902026451421122 0.926788966470517 GO:0005342 organic acid transmembrane transporter activity 1/227 189/18639 0.00529100529100529 0.434445143696245 0.902485060007129 0.926788966470517 GO:0008236 serine-type peptidase activity 1/227 194/18639 0.00515463917525773 0.423248103910259 0.90833875568715 0.931128616940949 GO:0017171 serine hydrolase activity 1/227 198/18639 0.00505050505050505 0.414697637164598 0.912768740979776 0.933177562227985 GO:0004842 ubiquitin-protein transferase activity 3/227 449/18639 0.0066815144766147 0.548620036694367 0.913600410572853 0.933177562227985 GO:0140097 catalytic activity, acting on DNA 2/227 336/18639 0.00595238095238095 0.488750786658276 0.918120745224637 0.936123112778062 GO:0004518 nuclease activity 1/227 209/18639 0.00478468899521531 0.392871445734882 0.923882327516187 0.938651316766002 GO:0051015 actin filament binding 1/227 209/18639 0.00478468899521531 0.392871445734882 0.923882327516187 0.938651316766002 GO:0000287 magnesium ion binding 1/227 230/18639 0.00434782608695652 0.357000574602567 0.941332976533216 0.954685217335105 GO:0061659 ubiquitin-like protein ligase activity 2/227 372/18639 0.00537634408602151 0.441452323433281 0.943159672505034 0.954844836589167 GO:0003713 transcription coactivator activity 1/227 256/18639 0.00390625 0.320742703744493 0.957518867160344 0.967669243844022 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 1/227 268/18639 0.00373134328358209 0.306381090143994 0.963404976612396 0.970644886988413 GO:0008514 organic anion transmembrane transporter activity 1/227 269/18639 0.00371747211895911 0.305242126983607 0.963857160505977 0.970644886988413 GO:0030371 translation repressor activity 1/227 329/18639 0.00303951367781155 0.249574869782949 0.982880375838571 0.988062521932623 GO:0061630 ubiquitin protein ligase activity 1/227 353/18639 0.0028328611898017 0.232606606681559 0.98731228869246 0.989508893877057 GO:0045182 translation regulator activity 1/227 356/18639 0.00280898876404494 0.230646438647726 0.987778983223426 0.989508893877057 GO:0140098 catalytic activity, acting on RNA 1/227 387/18639 0.00258397932816537 0.212170884130724 0.991705981297931 0.991705981297931