category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Cellular Processes Transport and catabolism hsa04137 Mitophagy - animal 2/14 105/9376 12.756462585034 CITED2/UBC 4.68460915383019 Human Diseases Cardiovascular disease hsa05418 Fluid shear stress and atherosclerosis 2/14 142/9376 9.43259557344065 SUMO2/HSP90AA1 3.91539738855526 Genetic Information Processing Folding, sorting and degradation hsa04141 Protein processing in endoplasmic reticulum 2/14 174/9376 7.69786535303777 HSP90AA1/DNAJA1 3.4485399382234 Metabolism Metabolism of cofactors and vitamins hsa00790 Folate biosynthesis 1/14 28/9376 23.9183673469388 DHFR 4.69643891175627 Human Diseases Drug resistance: antineoplastic hsa01523 Antifolate resistance 1/14 30/9376 22.3238095238095 DHFR 4.5235341274727 Genetic Information Processing Folding, sorting and degradation hsa03060 Protein export 1/14 31/9376 21.6036866359447 SPCS2 4.44325734749857 NA NA hsa04981 Folate transport and metabolism 1/14 31/9376 21.6036866359447 DHFR 4.44325734749857 Cellular Processes Cell growth and death hsa04215 Apoptosis - multiple species 1/14 32/9376 20.9285714285714 BCL2L11 4.36666705455723 Human Diseases Immune disease hsa05310 Asthma 1/14 32/9376 20.9285714285714 PRG2 4.36666705455723 Metabolism Metabolism of cofactors and vitamins hsa00670 One carbon pool by folate 1/14 39/9376 17.1721611721612 DHFR 3.91347012332065 Human Diseases Neurodegenerative disease hsa05012 Parkinson disease 2/14 268/9376 4.99786780383795 UBC/ATP5F1D 2.56773176096419 Genetic Information Processing Replication and repair hsa03410 Base excision repair 1/14 44/9376 15.2207792207792 MBD4 3.65618114645649 Genetic Information Processing Replication and repair hsa03460 Fanconi anemia pathway 1/14 54/9376 12.4021164021164 CENPX 3.24932489968686 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 2/14 362/9376 3.70007892659826 HSP90AA1/BCL2L11 2.02599003699625 Human Diseases Neurodegenerative disease hsa05014 Amyotrophic lateral sclerosis 2/14 368/9376 3.63975155279503 SRSF3/ATP5F1D 1.9977360754497 Organismal Systems Endocrine system hsa03320 PPAR signaling pathway 1/14 76/9376 8.81203007518797 UBC 2.64420161468924 Human Diseases Drug resistance: antineoplastic hsa01521 EGFR tyrosine kinase inhibitor resistance 1/14 80/9376 8.37142857142857 BCL2L11 2.560436061528 Organismal Systems Immune system hsa04612 Antigen processing and presentation 1/14 82/9376 8.16724738675958 HSP90AA1 2.52071255632341 Human Diseases Cancer: specific types hsa05210 Colorectal cancer 1/14 87/9376 7.69786535303777 BCL2L11 2.42703978320926 Organismal Systems Immune system hsa04657 IL-17 signaling pathway 1/14 94/9376 7.12462006079027 HSP90AA1 2.30774402353215 Human Diseases Cancer: specific types hsa05215 Prostate cancer 1/14 106/9376 6.31805929919137 HSP90AA1 2.12927413614187 Genetic Information Processing Translation hsa03013 Nucleocytoplasmic transport 1/14 108/9376 6.2010582010582 SUMO2 2.10220912307023 Organismal Systems Immune system hsa04659 Th17 cell differentiation 1/14 109/9376 6.14416775884666 HSP90AA1 2.08893116017768 Organismal Systems Endocrine system hsa04914 Progesterone-mediated oocyte maturation 1/14 110/9376 6.08831168831169 HSP90AA1 2.07581783392319 Human Diseases Neurodegenerative disease hsa05022 Pathways of neurodegeneration - multiple diseases 2/14 480/9376 2.79047619047619 UBC/ATP5F1D 1.55724562494812 Environmental Information Processing Signal transduction hsa04068 FoxO signaling pathway 1/14 133/9376 5.03544575725027 BCL2L11 1.8124924062311 Cellular Processes Cell growth and death hsa04210 Apoptosis 1/14 137/9376 4.88842544316997 BCL2L11 1.77291091533355 Metabolism Energy metabolism hsa00190 Oxidative phosphorylation 1/14 138/9376 4.85300207039337 ATP5F1D 1.76325508215894 Organismal Systems Endocrine system hsa04915 Estrogen signaling pathway 1/14 139/9376 4.81808838643371 HSP90AA1 1.75369168895254 Genetic Information Processing Folding, sorting and degradation hsa04120 Ubiquitin mediated proteolysis 1/14 142/9376 4.71629778672032 UBC 1.72554019963292 Metabolism Global and overview maps hsa01240 Biosynthesis of cofactors 1/14 154/9376 4.34879406307978 DHFR 1.62032293825298 Human Diseases Endocrine and metabolic disease hsa04932 Non-alcoholic fatty liver disease 1/14 157/9376 4.26569608735214 BCL2L11 1.59569183303925 Cellular Processes Cell growth and death hsa04217 Necroptosis 1/14 168/9376 3.98639455782313 HSP90AA1 1.5103740269092 Cellular Processes Transport and catabolism hsa04140 Autophagy - animal 1/14 169/9376 3.96280642434489 UBC 1.50297894286802 Environmental Information Processing Signal transduction hsa04310 Wnt signaling pathway 1/14 178/9376 3.76243980738363 CACYBP 1.43886967554505 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 1/14 180/9376 3.72063492063492 SRSF3 1.4251887221849 Organismal Systems Immune system hsa04621 NOD-like receptor signaling pathway 1/14 187/9376 3.58135981665393 HSP90AA1 1.378797732038 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 1/14 196/9376 3.41690962099125 UBC 1.32230744522269 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 1/14 205/9376 3.26689895470383 BCL2L11 1.26901303667406 Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 1/14 205/9376 3.26689895470383 ATP5F1D 1.26901303667406 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 1/14 216/9376 3.1005291005291 HSP90AA1 1.20773924561396 Human Diseases Cancer: overview hsa05207 Chemical carcinogenesis - receptor activation 1/14 217/9376 3.0862409479921 HSP90AA1 1.20236310252237 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 1/14 227/9376 2.95028319697923 ATP5F1D 1.15024176181875 Organismal Systems Environmental adaptation hsa04714 Thermogenesis 1/14 235/9376 2.84984802431611 ATP5F1D 1.11055088970329 Genetic Information Processing Transcription hsa03040 Spliceosome 1/14 243/9376 2.75602586713698 SRSF3 1.07248852605052 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 1/14 248/9376 2.70046082949309 HSP90AA1 1.04946991843418 Human Diseases Infectious disease: bacterial hsa05131 Shigellosis 1/14 253/9376 2.64709203839639 UBC 1.02700989686302 Human Diseases Neurodegenerative disease hsa05020 Prion disease 1/14 275/9376 2.43532467532468 ATP5F1D 0.934194440552355 Human Diseases Neurodegenerative disease hsa05016 Huntington disease 1/14 308/9376 2.17439703153989 ATP5F1D 0.810400844642147 Human Diseases Cancer: overview hsa05206 MicroRNAs in cancer 1/14 323/9376 2.0734188412207 BCL2L11 0.759170899894518 Human Diseases Neurodegenerative disease hsa05010 Alzheimer disease 1/14 388/9376 1.7260677466863 ATP5F1D 0.564841780785756