category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 3/16 214/9376 8.21495327102804 GNGT1/B2M/HLA-G 4.4142098016082 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 3/16 227/9376 7.74449339207048 GNGT1/B2M/HLA-G 4.25288024192312 Organismal Systems Immune system hsa04612 Antigen processing and presentation 2/16 82/9376 14.2926829268293 B2M/HLA-G 4.99834170574419 Metabolism Global and overview maps hsa01240 Biosynthesis of cofactors 2/16 154/9376 7.61038961038961 DHFR/NAPRT 3.41965712884061 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 2/16 180/9376 6.51111111111111 B2M/HLA-G 3.08662339409989 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 2/16 196/9376 5.97959183673469 GNGT1/HLA-G 2.91278310264821 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 2/16 205/9376 5.71707317073171 B2M/HLA-G 2.82324717332499 Metabolism Glycan biosynthesis and metabolism hsa00601 Glycosphingolipid biosynthesis - lacto and neolacto series 1/16 28/9376 20.9285714285714 B3GNT3 4.366199107849 Metabolism Metabolism of cofactors and vitamins hsa00790 Folate biosynthesis 1/16 28/9376 20.9285714285714 DHFR 4.366199107849 Organismal Systems Sensory system hsa04744 Phototransduction 1/16 29/9376 20.2068965517241 GNGT1 4.28279986228295 Human Diseases Drug resistance: antineoplastic hsa01523 Antifolate resistance 1/16 30/9376 19.5333333333333 DHFR 4.2034799577576 NA NA hsa04981 Folate transport and metabolism 1/16 31/9376 18.9032258064516 DHFR 4.12790970174366 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 2/16 224/9376 5.23214285714286 B2M/HLA-G 2.65053795510141 Metabolism Glycan biosynthesis and metabolism hsa00512 Mucin type O-glycan biosynthesis 1/16 36/9376 16.2777777777778 B3GNT3 3.79704466794569 Metabolism Metabolism of cofactors and vitamins hsa00760 Nicotinate and nicotinamide metabolism 1/16 38/9376 15.4210526315789 NAPRT 3.68272703963469 Metabolism Metabolism of cofactors and vitamins hsa00670 One carbon pool by folate 1/16 39/9376 15.025641025641 DHFR 3.62876670884235 Human Diseases Immune disease hsa05330 Allograft rejection 1/16 39/9376 15.025641025641 HLA-G 3.62876670884235 Metabolism Glycan biosynthesis and metabolism hsa00513 Various types of N-glycan biosynthesis 1/16 44/9376 13.3181818181818 TUSC3 3.38604938856394 Human Diseases Endocrine and metabolic disease hsa04940 Type I diabetes mellitus 1/16 44/9376 13.3181818181818 HLA-G 3.38604938856394 Human Diseases Immune disease hsa05332 Graft-versus-host disease 1/16 45/9376 13.0222222222222 HLA-G 3.34221680582886 Genetic Information Processing Folding, sorting and degradation hsa03050 Proteasome 1/16 46/9376 12.7391304347826 PSMB8 3.29975524056656 Human Diseases Immune disease hsa05320 Autoimmune thyroid disease 1/16 54/9376 10.8518518518519 HLA-G 3.00170430611191 Metabolism Glycan biosynthesis and metabolism hsa00510 N-Glycan biosynthesis 1/16 56/9376 10.4642857142857 TUSC3 2.93684891557685 Environmental Information Processing Signal transduction hsa04340 Hedgehog signaling pathway 1/16 56/9376 10.4642857142857 SCUBE2 2.93684891557685 Human Diseases Cardiovascular disease hsa05416 Viral myocarditis 1/16 70/9376 8.37142857142857 HLA-G 2.55933339001609 Human Diseases Infectious disease: bacterial hsa05133 Pertussis 1/16 78/9376 7.51282051282051 C2 2.38797263219971 Organismal Systems Immune system hsa04610 Complement and coagulation cascades 1/16 88/9376 6.65909090909091 C2 2.20513208566376 Organismal Systems Nervous system hsa04727 GABAergic synapse 1/16 89/9376 6.58426966292135 GNGT1 2.18842349027686 Human Diseases Substance dependence hsa05032 Morphine addiction 1/16 91/9376 6.43956043956044 GNGT1 2.15576419214647 Organismal Systems Environmental adaptation hsa04713 Circadian entrainment 1/16 97/9376 6.04123711340206 GNGT1 2.06338424324824 Human Diseases Infectious disease: bacterial hsa05150 Staphylococcus aureus infection 1/16 99/9376 5.91919191919192 C2 2.03430136626943 Cellular Processes Transport and catabolism hsa04137 Mitophagy - animal 1/16 105/9376 5.58095238095238 CCZ1B 1.95161811886993 Organismal Systems Nervous system hsa04725 Cholinergic synapse 1/16 115/9376 5.09565217391304 GNGT1 1.82705133514084 Organismal Systems Nervous system hsa04726 Serotonergic synapse 1/16 115/9376 5.09565217391304 GNGT1 1.82705133514084 Organismal Systems Endocrine system hsa04928 Parathyroid hormone synthesis, secretion and action 1/16 115/9376 5.09565217391304 SLC12A3 1.82705133514084 Organismal Systems Nervous system hsa04724 Glutamatergic synapse 1/16 116/9376 5.05172413793103 GNGT1 1.81539474991399 Environmental Information Processing Signal transduction hsa04071 Sphingolipid signaling pathway 1/16 125/9376 4.688 SPTSSA 1.71616596014958 Organismal Systems Endocrine system hsa04926 Relaxin signaling pathway 1/16 130/9376 4.50769230769231 GNGT1 1.66503714720288 Organismal Systems Immune system hsa04650 Natural killer cell mediated cytotoxicity 1/16 133/9376 4.40601503759398 HLA-G 1.63558684988578 Organismal Systems Nervous system hsa04728 Dopaminergic synapse 1/16 133/9376 4.40601503759398 GNGT1 1.63558684988578 Environmental Information Processing Signal transduction hsa04371 Apelin signaling pathway 1/16 140/9376 4.18571428571429 GNGT1 1.57013351521341 Human Diseases Immune disease hsa05322 Systemic lupus erythematosus 1/16 143/9376 4.0979020979021 C2 1.54337689669556 Human Diseases Endocrine and metabolic disease hsa04936 Alcoholic liver disease 1/16 144/9376 4.06944444444444 C2 1.53461991763775 Organismal Systems Nervous system hsa04723 Retrograde endocannabinoid signaling 1/16 149/9376 3.93288590604027 GNGT1 1.49198943422366 Cellular Processes Transport and catabolism hsa04145 Phagosome 1/16 155/9376 3.78064516129032 HLA-G 1.44321194664503 Cellular Processes Cell growth and death hsa04218 Cellular senescence 1/16 157/9376 3.73248407643312 HLA-G 1.42749062151271 Environmental Information Processing Signaling molecules and interaction hsa04514 Cell adhesion molecule (CAM) interaction 1/16 160/9376 3.6625 HLA-G 1.40438466919805 Genetic Information Processing Folding, sorting and degradation hsa04141 Protein processing in endoplasmic reticulum 1/16 174/9376 3.36781609195402 TUSC3 1.30343441187191 Organismal Systems Development and regeneration hsa04360 Axon guidance 1/16 184/9376 3.18478260869565 SLIT2 1.23742771527244 Human Diseases Substance dependence hsa05034 Alcoholism 1/16 191/9376 3.06806282722513 GNGT1 1.1938466272815 Organismal Systems Immune system hsa04062 Chemokine signaling pathway 1/16 193/9376 3.03626943005181 GNGT1 1.18176006231583 NA NA hsa04082 Neuroactive ligand signaling 1/16 199/9376 2.94472361809045 GNGT1 1.14641475257723 Human Diseases Cancer: overview hsa05202 Transcriptional misregulation in cancer 1/16 201/9376 2.91542288557214 ASPSCR1 1.1349255403894 Human Diseases Cancer: overview hsa05203 Viral carcinogenesis 1/16 205/9376 2.85853658536585 HLA-G 1.11236522547758 NA NA hsa04081 Hormone signaling 1/16 219/9376 2.67579908675799 GNGT1 1.0374689431857 Cellular Processes Cell motility hsa04820 Cytoskeleton in muscle cells 1/16 233/9376 2.51502145922747 FBLN1 0.968188879655745 Environmental Information Processing Signal transduction hsa04014 Ras signaling pathway 1/16 238/9376 2.46218487394958 GNGT1 0.944654273741651 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 1/16 238/9376 2.46218487394958 C2 0.944654273741651 Cellular Processes Transport and catabolism hsa04144 Endocytosis 1/16 250/9376 2.344 HLA-G 0.890505786794317 NA NA hsa04517 IgSF CAM signaling 1/16 299/9376 1.95986622073579 SLIT2 0.69740144037304 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 1/16 333/9376 1.75975975975976 HLA-G 0.583646444446489 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 1/16 362/9376 1.61878453038674 GNGT1 0.496412445783599