category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	4/34	83/9376	13.2898653437279	PHYH/FAR2/CAT/ACSL5	6.78443002270659
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	2/34	30/9376	18.3843137254902	DHFR/ABCG2	5.75321302661893
NA	NA	hsa04981	Folate transport and metabolism	2/34	31/9376	17.7912713472486	DHFR/ABCG2	5.64910880009271
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	2/34	45/9376	12.2562091503268	ABCC9/ABCG2	4.566037579369
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	3/34	140/9376	5.90924369747899	GNGT1/APELA/CCN2	3.53054549478097
Metabolism	Lipid metabolism	hsa00061	Fatty acid biosynthesis	1/34	18/9376	15.3202614379085	ACSL5	3.66860407484938
NA	NA	hsa04517	IgSF CAM signaling	3/34	299/9376	2.76686995868582	NLGN4X/SLIT2/NECTIN2	1.87315699467865
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	4/34	480/9376	2.29803921568627	GPX3/COX7B2/CAT/DKK1	1.76123055042996
Metabolism	Glycan biosynthesis and metabolism	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	1/34	28/9376	9.84873949579832	B3GNT3	2.82882602512454
Metabolism	Metabolism of cofactors and vitamins	hsa00790	Folate biosynthesis	1/34	28/9376	9.84873949579832	DHFR	2.82882602512454
Organismal Systems	Sensory system	hsa04744	Phototransduction	1/34	29/9376	9.50912778904665	GNGT1	2.76855457369724
Metabolism	Carbohydrate metabolism	hsa00630	Glyoxylate and dicarboxylate metabolism	1/34	31/9376	8.89563567362429	CAT	2.65633876338408
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	2/34	154/9376	3.58135981665393	DHFR/NAPRT	1.94850494340457
Human Diseases	Immune disease	hsa05310	Asthma	1/34	32/9376	8.61764705882353	PRG2	2.60396166627547
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	2/34	160/9376	3.44705882352941	NLGN4X/NECTIN2	1.88338164157756
Metabolism	Glycan biosynthesis and metabolism	hsa00512	Mucin type O-glycan biosynthesis	1/34	36/9376	7.66013071895425	B3GNT3	2.41527024284522
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	1/34	38/9376	7.25696594427245	NAPRT	2.33149141125672
Metabolism	Metabolism of cofactors and vitamins	hsa00670	One carbon pool by folate	1/34	39/9376	7.07088989441931	DHFR	2.29184976623435
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	1/34	42/9376	6.56582633053221	CAT	2.1808488327918
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	1/34	42/9376	6.56582633053221	ACSL5	2.1808488327918
Metabolism	Lipid metabolism	hsa00071	Fatty acid degradation	1/34	43/9376	6.41313269493844	ACSL5	2.14623579330221
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	3/34	368/9376	2.24808184143223	GPX3/COX7B2/CAT	1.47352649931344
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	1/34	44/9376	6.26737967914439	TUSC3	2.11270452451728
NA	NA	hsa03272	Virion - Hepatitis viruses	1/34	48/9376	5.74509803921569	CD81	1.98827615944298
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	1/34	50/9376	5.51529411764706	CD81	1.9312055752829
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	2/34	204/9376	2.70357554786621	CAV1/LUM	1.48405372642519
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	2/34	214/9376	2.57724024189115	GNGT1/TRIM5	1.40803923758028
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	1/34	55/9376	5.01390374331551	ASAH1	1.80103523589128
Metabolism	Glycan biosynthesis and metabolism	hsa00510	N-Glycan biosynthesis	1/34	56/9376	4.92436974789916	TUSC3	1.77689244874649
Metabolism	Global and overview maps	hsa01212	Fatty acid metabolism	1/34	57/9376	4.83797729618163	ACSL5	1.7533165753578
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/34	59/9376	4.67397806580259	GPX3	1.7077711889639
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	2/34	227/9376	2.4296449857476	COX7B2/CAT	1.31540499122504
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	1/34	62/9376	4.44781783681214	CAT	1.6431499778268
Metabolism	Amino acid metabolism	hsa00310	Lysine degradation	1/34	63/9376	4.37721755368814	SMYD3	1.62251857130544
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	1/34	63/9376	4.37721755368814	PTGDS	1.62251857130544
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	2/34	235/9376	2.34693366708385	COX7B2/ACSL5	1.26150347244954
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/34	70/9376	3.93949579831933	ACSL5	1.48917420500881
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	1/34	70/9376	3.93949579831933	CAV1	1.48917420500881
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	2/34	250/9376	2.20611764705882	ASAH1/CTSH	1.16606996496861
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	1/34	73/9376	3.77759871071716	TRIM5	1.43722441671385
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/34	75/9376	3.67686274509804	GPX3	1.40409689275682
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/34	76/9376	3.62848297213622	ACSL5	1.38795586059867
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	1/34	78/9376	3.53544494720965	CAV1	1.35647527058173
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	2/34	275/9376	2.0055614973262	COX7B2/CAV1	1.02102315435738
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	1/34	87/9376	3.16970926301555	COX7B2	1.22654038748558
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	1/34	89/9376	3.09847984137475	GNGT1	1.19996132092606
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/34	90/9376	3.0640522875817	CAT	1.18695095758356
Organismal Systems	Digestive system	hsa04976	Bile secretion	1/34	90/9376	3.0640522875817	ABCG2	1.18695095758356
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/34	91/9376	3.03038138332256	CD81	1.17412011940079
Human Diseases	Substance dependence	hsa05032	Morphine addiction	1/34	91/9376	3.03038138332256	GNGT1	1.17412011940079
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	1/34	93/9376	2.9652118912081	NECTIN2	1.14897835578995
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	1/34	97/9376	2.84293511218921	GNGT1	1.10065317180431
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	2/34	308/9376	1.79067990832697	GPX3/COX7B2	0.851187958204541
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	1/34	105/9376	2.62633053221289	CCZ1B	1.01098646102553
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	1/34	110/9376	2.50695187165775	SPDYE2	0.959079795776242
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	1/34	115/9376	2.39795396419437	GNGT1	0.909951013991676
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/34	115/9376	2.39795396419437	GNGT1	0.909951013991676
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	1/34	116/9376	2.37728194726166	CAT	0.900433245538203
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	1/34	116/9376	2.37728194726166	GNGT1	0.900433245538203
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	1/34	125/9376	2.20611764705882	ASAH1	0.818946447010456
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	1/34	130/9376	2.12126696832579	GNGT1	0.77662063415708
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	1/34	133/9376	2.0734188412207	CAT	0.752131405548803
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	1/34	133/9376	2.0734188412207	GNGT1	0.752131405548803
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	1/34	137/9376	2.01288106483469	CTSH	0.720462561156388
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	1/34	138/9376	1.99829497016198	COX7B2	0.712712888368271
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	1/34	138/9376	1.99829497016198	SPDYE2	0.712712888368271
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	1/34	142/9376	1.94200497100249	CAV1	0.682350630092204
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	2/34	388/9376	1.4214675560946	COX7B2/DKK1	0.51150943058739
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	1/34	149/9376	1.8507698381366	GNGT1	0.631509842703638
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	1/34	156/9376	1.76772247360483	CD81	0.583319181630171
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	1/34	157/9376	1.75646309479206	CCN2	0.576634774155491
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	1/34	157/9376	1.75646309479206	COX7B2	0.576634774155491
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	1/34	174/9376	1.58485463150778	TUSC3	0.4697714381672
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	1/34	178/9376	1.54923992068738	DKK1	0.446303774244058
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	1/34	180/9376	1.53202614379085	NECTIN2	0.434785358378735
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/34	184/9376	1.49872122762148	SLIT2	0.412161026412039
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/34	191/9376	1.44379427163536	GNGT1	0.373821228799141
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	1/34	193/9376	1.42883267296556	GNGT1	0.363144436194341
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	1/34	196/9376	1.40696278511405	GNGT1	0.347349403274472
NA	NA	hsa04082	Neuroactive ligand signaling	1/34	199/9376	1.3857522908661	GNGT1	0.331810291053044
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	1/34	201/9376	1.37196371085748	NUPR1	0.321588662357798
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	1/34	203/9376	1.35844682700666	CAV1	0.311474306674279
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	1/34	205/9376	1.34519368723099	COX7B2	0.301464788991173
NA	NA	hsa04382	Cornified envelope formation	1/34	217/9376	1.27080509623204	PCSK6	0.243482546734595
NA	NA	hsa04081	Hormone signaling	1/34	219/9376	1.25919957023905	GNGT1	0.234145002442275
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	1/34	224/9376	1.23109243697479	MSX1	0.211182001252287
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	1/34	227/9376	1.2148224928738	GNGT1	0.197656468683263
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	1/34	238/9376	1.1586752347998	GNGT1	0.149581270111815
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	1/34	250/9376	1.10305882352941	CAV1	0.0996368795661827
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	1/34	268/9376	1.02897278314311	COX7B2	0.0290302828355838
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	1/34	362/9376	0.761780955476113	GNGT1	-0.278854175585576
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	1/34	370/9376	0.745310015898251	APELA	-0.301544854576744
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	1/34	449/9376	0.614175291497445	OR56A3	-0.50543534072058