ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0015459	potassium channel regulator activity	4/47	59/18639	0.0677966101694915	26.8864046159394	1.45883789564319e-05	0.00316567823354571
GO:0099106	ion channel regulator activity	4/47	160/18639	0.025	9.91436170212766	0.000699823165862632	0.0397824105037989
GO:0016247	channel regulator activity	4/47	168/18639	0.0238095238095238	9.44224924012158	0.000839749107519907	0.0397824105037989
GO:0141108	transporter regulator activity	4/47	170/18639	0.0235294117647059	9.33116395494368	0.000877602372065862	0.0397824105037989
GO:0008201	heparin binding	4/47	172/18639	0.0232558139534884	9.22266204849085	0.000916645403313339	0.0397824105037989
GO:0030021	extracellular matrix structural constituent conferring compression resistance	2/47	22/18639	0.0909090909090909	36.0522243713733	0.00139211253766722	0.0503480701122978
GO:0043236	laminin binding	2/47	29/18639	0.0689655172413793	27.3499633162142	0.00241940836284473	0.0750016592481866
GO:0005539	glycosaminoglycan binding	4/47	242/18639	0.0165289256198347	6.55494988570424	0.00319178058411945	0.0865770483442401
GO:0044325	transmembrane transporter binding	3/47	136/18639	0.0220588235294118	8.7479662077597	0.00487364900126506	0.109054228770617
GO:1901681	sulfur compound binding	4/47	275/18639	0.0145454545454545	5.76835589941973	0.00502554049634178	0.109054228770617
GO:0140359	ABC-type transporter activity	2/47	47/18639	0.0425531914893617	16.8755092802173	0.00625875791286848	0.123468224281133
GO:0015485	cholesterol binding	2/47	54/18639	0.037037037037037	14.6879432624113	0.00819300216090383	0.126915582281303
GO:0050661	NADP binding	2/47	54/18639	0.037037037037037	14.6879432624113	0.00819300216090383	0.126915582281303
GO:0004601	peroxidase activity	2/47	57/18639	0.0350877192982456	13.9148936170213	0.00909401424963573	0.126915582281303
GO:0016504	peptidase activator activity	2/47	57/18639	0.0350877192982456	13.9148936170213	0.00909401424963573	0.126915582281303
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	2/47	59/18639	0.0338983050847458	13.4432023079697	0.0097182084071522	0.126915582281303
GO:0031406	carboxylic acid binding	3/47	187/18639	0.0160427807486631	6.36215724200706	0.0116586806726579	0.126915582281303
GO:0043177	organic acid binding	3/47	189/18639	0.0158730158730159	6.29483282674772	0.0119968765486683	0.126915582281303
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	2/47	67/18639	0.0298507462686567	11.838043823436	0.0123989081669969	0.126915582281303
GO:0050840	extracellular matrix binding	2/47	67/18639	0.0298507462686567	11.838043823436	0.0123989081669969	0.126915582281303
GO:0032934	sterol binding	2/47	68/18639	0.0294117647058824	11.6639549436796	0.0127542892222208	0.126915582281303
GO:0008236	serine-type peptidase activity	3/47	194/18639	0.0154639175257732	6.13259486729546	0.0128670175584731	0.126915582281303
GO:0017171	serine hydrolase activity	3/47	198/18639	0.0151515151515152	6.00870406189555	0.0135886057955738	0.128205541636501
GO:0098631	cell adhesion mediator activity	2/47	76/18639	0.0263157894736842	10.436170212766	0.0157548531996867	0.142450131013834
GO:0001618	virus receptor activity	2/47	81/18639	0.0246913580246914	9.7919621749409	0.0177688857645134	0.147821337088696
GO:0140272	exogenous protein binding	2/47	82/18639	0.024390243902439	9.67254800207577	0.0181841729144535	0.147821337088696
GO:0016209	antioxidant activity	2/47	86/18639	0.0232558139534884	9.22266204849085	0.0198861728803761	0.147821337088696
GO:0043178	alcohol binding	2/47	92/18639	0.0217391304347826	8.62118408880666	0.0225592857735925	0.147821337088696
GO:0008276	protein methyltransferase activity	2/47	95/18639	0.0210526315789474	8.34893617021276	0.0239486115061035	0.147821337088696
GO:0043121	neurotrophin binding	1/47	10/18639	0.1	39.6574468085106	0.0249376839563958	0.147821337088696
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/47	10/18639	0.1	39.6574468085106	0.0249376839563958	0.147821337088696
GO:0140999	histone H3K4 trimethyltransferase activity	1/47	10/18639	0.1	39.6574468085106	0.0249376839563958	0.147821337088696
GO:0141109	transporter activator activity	1/47	10/18639	0.1	39.6574468085106	0.0249376839563958	0.147821337088696
GO:0005249	voltage-gated potassium channel activity	2/47	98/18639	0.0204081632653061	8.09335649153278	0.0253723397506377	0.147821337088696
GO:0042626	ATPase-coupled transmembrane transporter activity	2/47	98/18639	0.0204081632653061	8.09335649153278	0.0253723397506377	0.147821337088696
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	1/47	11/18639	0.0909090909090909	36.0522243713733	0.0273977155659323	0.147821337088696
GO:0005225	volume-sensitive anion channel activity	1/47	11/18639	0.0909090909090909	36.0522243713733	0.0273977155659323	0.147821337088696
GO:0008172	S-methyltransferase activity	1/47	11/18639	0.0909090909090909	36.0522243713733	0.0273977155659323	0.147821337088696
GO:0047676	arachidonate-CoA ligase activity	1/47	11/18639	0.0909090909090909	36.0522243713733	0.0273977155659323	0.147821337088696
GO:0050998	nitric-oxide synthase binding	1/47	11/18639	0.0909090909090909	36.0522243713733	0.0273977155659323	0.147821337088696
GO:0005095	GTPase inhibitor activity	1/47	12/18639	0.0833333333333333	33.0478723404255	0.0298516723711931	0.147821337088696
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	1/47	12/18639	0.0833333333333333	33.0478723404255	0.0298516723711931	0.147821337088696
GO:1990459	transferrin receptor binding	1/47	12/18639	0.0833333333333333	33.0478723404255	0.0298516723711931	0.147821337088696
GO:0005496	steroid binding	2/47	108/18639	0.0185185185185185	7.34397163120567	0.0303592322660422	0.147821337088696
GO:0005542	folic acid binding	1/47	13/18639	0.0769230769230769	30.505728314239	0.0322995690479829	0.147821337088696
GO:0039706	co-receptor binding	1/47	13/18639	0.0769230769230769	30.505728314239	0.0322995690479829	0.147821337088696
GO:0046975	histone H3K36 methyltransferase activity	1/47	13/18639	0.0769230769230769	30.505728314239	0.0322995690479829	0.147821337088696
GO:0008559	ABC-type xenobiotic transporter activity	1/47	14/18639	0.0714285714285714	28.3267477203647	0.0347414202374355	0.147821337088696
GO:0031404	chloride ion binding	1/47	14/18639	0.0714285714285714	28.3267477203647	0.0347414202374355	0.147821337088696
GO:0042043	neurexin family protein binding	1/47	14/18639	0.0714285714285714	28.3267477203647	0.0347414202374355	0.147821337088696
GO:1990825	sequence-specific mRNA binding	1/47	14/18639	0.0714285714285714	28.3267477203647	0.0347414202374355	0.147821337088696
GO:0004467	long-chain fatty acid-CoA ligase activity	1/47	15/18639	0.0666666666666667	26.4382978723404	0.0371772405460976	0.150574734224415
GO:0048531	beta-1,3-galactosyltransferase activity	1/47	15/18639	0.0666666666666667	26.4382978723404	0.0371772405460976	0.150574734224415
GO:0005267	potassium channel activity	2/47	124/18639	0.0161290322580645	6.39636238846946	0.0390686099902212	0.150574734224415
GO:0008142	oxysterol binding	1/47	16/18639	0.0625	24.7859042553191	0.0396070445460083	0.150574734224415
GO:0015562	efflux transmembrane transporter activity	1/47	16/18639	0.0625	24.7859042553191	0.0396070445460083	0.150574734224415
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	1/47	17/18639	0.0588235294117647	23.3279098873592	0.0420308467747758	0.150574734224415
GO:0070402	NADPH binding	1/47	17/18639	0.0588235294117647	23.3279098873592	0.0420308467747758	0.150574734224415
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	2/47	130/18639	0.0153846153846154	6.10114566284779	0.0425523879746509	0.150574734224415
GO:0005179	hormone activity	2/47	132/18639	0.0151515151515152	6.00870406189555	0.0437388115474035	0.150574734224415
GO:0000900	mRNA regulatory element binding translation repressor activity	1/47	18/18639	0.0555555555555556	22.031914893617	0.0444486617356602	0.150574734224415
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	1/47	18/18639	0.0555555555555556	22.031914893617	0.0444486617356602	0.150574734224415
GO:0032393	MHC class I receptor activity	1/47	18/18639	0.0555555555555556	22.031914893617	0.0444486617356602	0.150574734224415
GO:0019838	growth factor binding	2/47	136/18639	0.0147058823529412	5.8319774718398	0.0461485060072594	0.150574734224415
GO:0005520	insulin-like growth factor binding	1/47	19/18639	0.0526315789473684	20.8723404255319	0.0468605038976508	0.150574734224415
GO:0042800	histone H3K4 methyltransferase activity	1/47	19/18639	0.0526315789473684	20.8723404255319	0.0468605038976508	0.150574734224415
GO:0046624	sphingolipid transporter activity	1/47	19/18639	0.0526315789473684	20.8723404255319	0.0468605038976508	0.150574734224415
GO:0015095	magnesium ion transmembrane transporter activity	1/47	20/18639	0.05	19.8287234042553	0.0492663876955459	0.150574734224415
GO:0016505	peptidase activator activity involved in apoptotic process	1/47	20/18639	0.05	19.8287234042553	0.0492663876955459	0.150574734224415
GO:0031418	L-ascorbic acid binding	1/47	20/18639	0.05	19.8287234042553	0.0492663876955459	0.150574734224415
GO:0140939	histone H4 methyltransferase activity	1/47	20/18639	0.05	19.8287234042553	0.0492663876955459	0.150574734224415
GO:0022843	voltage-gated monoatomic cation channel activity	2/47	143/18639	0.013986013986014	5.54649605713435	0.0504806208721787	0.152142982350872
GO:0019842	vitamin binding	2/47	150/18639	0.0133333333333333	5.28765957446809	0.0549539836096916	0.161175130327532
GO:0004602	glutathione peroxidase activity	1/47	23/18639	0.0434782608695652	17.2423681776133	0.0564484327414396	0.161175130327532
GO:0031681	G-protein beta-subunit binding	1/47	23/18639	0.0434782608695652	17.2423681776133	0.0564484327414396	0.161175130327532
GO:0140103	catalytic activity, acting on a glycoprotein	1/47	23/18639	0.0434782608695652	17.2423681776133	0.0564484327414396	0.161175130327532
GO:0015645	fatty acid ligase activity	1/47	25/18639	0.04	15.8629787234043	0.0612069340581146	0.165372868099247
GO:0120515	fatty acid-CoA ligase activity	1/47	25/18639	0.04	15.8629787234043	0.0612069340581146	0.165372868099247
GO:0015079	potassium ion transmembrane transporter activity	2/47	160/18639	0.0125	4.95718085106383	0.0615775750859777	0.165372868099247
GO:0005178	integrin binding	2/47	161/18639	0.0124223602484472	4.92639090788952	0.0622544493743489	0.165372868099247
GO:0008198	ferrous iron binding	1/47	26/18639	0.0384615384615385	15.2528641571195	0.0635773688974435	0.165372868099247
GO:0050750	low-density lipoprotein particle receptor binding	1/47	26/18639	0.0384615384615385	15.2528641571195	0.0635773688974435	0.165372868099247
GO:0015399	primary active transmembrane transporter activity	2/47	166/18639	0.0120481927710843	4.77800563957959	0.0656770654237582	0.165372868099247
GO:0016405	CoA-ligase activity	1/47	27/18639	0.037037037037037	14.6879432624113	0.0659419454655311	0.165372868099247
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	1/47	27/18639	0.037037037037037	14.6879432624113	0.0659419454655311	0.165372868099247
GO:0023026	MHC class II protein complex binding	1/47	27/18639	0.037037037037037	14.6879432624113	0.0659419454655311	0.165372868099247
GO:0016874	ligase activity	2/47	167/18639	0.0119760479041916	4.74939482736654	0.0663691220381417	0.165372868099247
GO:0005201	extracellular matrix structural constituent	2/47	168/18639	0.0119047619047619	4.72112462006079	0.067063651579418	0.165372868099247
GO:0005242	inward rectifier potassium channel activity	1/47	28/18639	0.0357142857142857	14.1633738601824	0.0683006779264766	0.166530866405005
GO:0005244	voltage-gated monoatomic ion channel activity	2/47	173/18639	0.0115606936416185	4.58467593161973	0.0705728267129785	0.168481614825975
GO:0035250	UDP-galactosyltransferase activity	1/47	29/18639	0.0344827586206897	13.6749816581071	0.0706535804108925	0.168481614825975
GO:0022832	voltage-gated channel activity	2/47	175/18639	0.0114285714285714	4.53227963525836	0.0719932434116527	0.168522816409231
GO:0004252	serine-type endopeptidase activity	2/47	176/18639	0.0113636363636364	4.50652804642166	0.0727069767125721	0.168522816409231
GO:0048019	receptor antagonist activity	1/47	30/18639	0.0333333333333333	13.2191489361702	0.0730006670159804	0.168522816409231
GO:0016878	acid-thiol ligase activity	1/47	31/18639	0.032258064516129	12.7927247769389	0.0753419518056113	0.170304203560601
GO:0070325	lipoprotein particle receptor binding	1/47	31/18639	0.032258064516129	12.7927247769389	0.0753419518056113	0.170304203560601
GO:0008378	galactosyltransferase activity	1/47	32/18639	0.03125	12.3929521276596	0.0776774488104016	0.172000065223032
GO:0042910	xenobiotic transmembrane transporter activity	1/47	32/18639	0.03125	12.3929521276596	0.0776774488104016	0.172000065223032
GO:0140311	protein sequestering activity	1/47	33/18639	0.0303030303030303	12.0174081237911	0.0800071720277885	0.173615563300301
GO:0140416	transcription regulator inhibitor activity	1/47	33/18639	0.0303030303030303	12.0174081237911	0.0800071720277885	0.173615563300301
GO:0090482	vitamin transmembrane transporter activity	1/47	34/18639	0.0294117647058824	11.6639549436796	0.082331135422107	0.176889667194032
GO:0000993	RNA polymerase II complex binding	1/47	36/18639	0.0277777777777778	11.0159574468085	0.0869618384338354	0.185007048432768
GO:0023023	MHC protein complex binding	1/47	37/18639	0.027027027027027	10.718228867165	0.0892686058150974	0.185706711696718
GO:0043394	proteoglycan binding	1/47	37/18639	0.027027027027027	10.718228867165	0.0892686058150974	0.185706711696718
GO:0005501	retinoid binding	1/47	38/18639	0.0263157894736842	10.436170212766	0.0915696689011467	0.185706711696718
GO:0019840	isoprenoid binding	1/47	38/18639	0.0263157894736842	10.436170212766	0.0915696689011467	0.185706711696718
GO:0042887	amide transmembrane transporter activity	1/47	38/18639	0.0263157894736842	10.436170212766	0.0915696689011467	0.185706711696718
GO:0008168	methyltransferase activity	2/47	204/18639	0.00980392156862745	3.88798498122653	0.0935811707729398	0.186299803625027
GO:0004177	aminopeptidase activity	1/47	40/18639	0.025	9.91436170212766	0.0961547373548526	0.186299803625027
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	1/47	40/18639	0.025	9.91436170212766	0.0961547373548526	0.186299803625027
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	1/47	40/18639	0.025	9.91436170212766	0.0961547373548526	0.186299803625027
GO:0071855	neuropeptide receptor binding	1/47	40/18639	0.025	9.91436170212766	0.0961547373548526	0.186299803625027
GO:0016877	ligase activity, forming carbon-sulfur bonds	1/47	41/18639	0.024390243902439	9.67254800207577	0.0984387702245945	0.187219467365601
GO:0042287	MHC protein binding	1/47	41/18639	0.024390243902439	9.67254800207577	0.0984387702245945	0.187219467365601
GO:0043175	RNA polymerase core enzyme binding	1/47	42/18639	0.0238095238095238	9.44224924012158	0.100717153803444	0.187219467365601
GO:0016741	transferase activity, transferring one-carbon groups	2/47	215/18639	0.00930232558139535	3.68906481939634	0.102209630039931	0.187219467365601
GO:0008200	ion channel inhibitor activity	1/47	43/18639	0.0232558139534884	9.22266204849085	0.102989901761245	0.187219467365601
GO:0008375	acetylglucosaminyltransferase activity	1/47	43/18639	0.0232558139534884	9.22266204849085	0.102989901761245	0.187219467365601
GO:0005216	monoatomic ion channel activity	3/47	448/18639	0.00669642857142857	2.65563259878419	0.103190962110294	0.187219467365601
GO:0046873	metal ion transmembrane transporter activity	3/47	450/18639	0.00666666666666667	2.64382978723404	0.10422724433799	0.187219467365601
GO:0016248	channel inhibitor activity	1/47	44/18639	0.0227272727272727	9.01305609284333	0.105257027735499	0.187219467365601
GO:0030547	signaling receptor inhibitor activity	1/47	44/18639	0.0227272727272727	9.01305609284333	0.105257027735499	0.187219467365601
GO:0141110	transporter inhibitor activity	1/47	45/18639	0.0222222222222222	8.81276595744681	0.107518545331435	0.189687189731069
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	1/47	46/18639	0.0217391304347826	8.62118408880666	0.109774468122089	0.191412470029116
GO:0061134	peptidase regulator activity	2/47	226/18639	0.00884955752212389	3.50950856712483	0.111051205443679	0.191412470029116
GO:0005504	fatty acid binding	1/47	47/18639	0.0212765957446809	8.43775464010865	0.112024809648377	0.191412470029116
GO:0140938	histone H3 methyltransferase activity	1/47	47/18639	0.0212765957446809	8.43775464010865	0.112024809648377	0.191412470029116
GO:0016879	ligase activity, forming carbon-nitrogen bonds	1/47	48/18639	0.0208333333333333	8.26196808510638	0.114269583419167	0.19222092714697
GO:0038187	pattern recognition receptor activity	1/47	48/18639	0.0208333333333333	8.26196808510638	0.114269583419167	0.19222092714697
GO:0016860	intramolecular oxidoreductase activity	1/47	53/18639	0.0188679245283019	7.48253713368125	0.125410406517178	0.208686859734295
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	1/47	54/18639	0.0185185185185185	7.34397163120567	0.127622055655976	0.208686859734295
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	1/47	54/18639	0.0185185185185185	7.34397163120567	0.127622055655976	0.208686859734295
GO:0003712	transcription coregulator activity	3/47	495/18639	0.00606060606060606	2.40348162475822	0.128612187051949	0.208686859734295
GO:0098632	cell-cell adhesion mediator activity	1/47	55/18639	0.0181818181818182	7.21044487427466	0.129828230710276	0.208686859734295
GO:0140313	molecular sequestering activity	1/47	55/18639	0.0181818181818182	7.21044487427466	0.129828230710276	0.208686859734295
GO:0003713	transcription coactivator activity	2/47	256/18639	0.0078125	3.09823803191489	0.136109965888749	0.217175460278372
GO:0070063	RNA polymerase binding	1/47	59/18639	0.0169491525423729	6.72160115398485	0.138598454715265	0.218205059199081
GO:0001098	basal transcription machinery binding	1/47	60/18639	0.0166666666666667	6.60957446808511	0.140777457547794	0.218205059199081
GO:0001099	basal RNA polymerase II transcription machinery binding	1/47	60/18639	0.0166666666666667	6.60957446808511	0.140777457547794	0.218205059199081
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	1/47	60/18639	0.0166666666666667	6.60957446808511	0.140777457547794	0.218205059199081
GO:0015026	coreceptor activity	1/47	61/18639	0.0163934426229508	6.50122078828043	0.142951065357431	0.22000270342243
GO:1901682	sulfur compound transmembrane transporter activity	1/47	63/18639	0.0158730158730159	6.29483282674772	0.147282148148806	0.22507201512881
GO:0042054	histone methyltransferase activity	1/47	67/18639	0.0149253731343284	5.91902191171801	0.155880146376091	0.236330339088958
GO:0030246	carbohydrate binding	2/47	280/18639	0.00714285714285714	2.83267477203647	0.156985023730609	0.236330339088958
GO:0002039	p53 binding	1/47	69/18639	0.0144927536231884	5.74745605920444	0.160147268680391	0.236330339088958
GO:0016279	protein-lysine N-methyltransferase activity	1/47	69/18639	0.0144927536231884	5.74745605920444	0.160147268680391	0.236330339088958
GO:0008028	monocarboxylic acid transmembrane transporter activity	1/47	70/18639	0.0142857142857143	5.66534954407295	0.162272905641727	0.236330339088958
GO:0016278	lysine N-methyltransferase activity	1/47	70/18639	0.0142857142857143	5.66534954407295	0.162272905641727	0.236330339088958
GO:0097110	scaffold protein binding	1/47	70/18639	0.0142857142857143	5.66534954407295	0.162272905641727	0.236330339088958
GO:0005518	collagen binding	1/47	72/18639	0.0138888888888889	5.50797872340426	0.166508395142506	0.240882144972826
GO:0048029	monosaccharide binding	1/47	74/18639	0.0135135135135135	5.35911443358252	0.170722923673749	0.245343539319228
GO:0033293	monocarboxylic acid binding	1/47	79/18639	0.0126582278481013	5.01992997576084	0.181168205602111	0.258641451418803
GO:0022836	gated channel activity	2/47	318/18639	0.00628930817610063	2.49417904456042	0.191153676780808	0.268078562000212
GO:0004860	protein kinase inhibitor activity	1/47	84/18639	0.0119047619047619	4.72112462006079	0.191484687143008	0.268078562000212
GO:0051117	ATPase binding	1/47	84/18639	0.0119047619047619	4.72112462006079	0.191484687143008	0.268078562000212
GO:0004197	cysteine-type endopeptidase activity	1/47	88/18639	0.0113636363636364	4.50652804642166	0.199646181085411	0.277712957022655
GO:0019210	kinase inhibitor activity	1/47	90/18639	0.0111111111111111	4.4063829787234	0.203696635392362	0.28154248331301
GO:0072341	modified amino acid binding	1/47	91/18639	0.010989010989011	4.35796118774842	0.205714332202786	0.282531709417751
GO:0051213	dioxygenase activity	1/47	93/18639	0.010752688172043	4.26424159231297	0.209734725987101	0.286157275910204
GO:0042562	hormone binding	1/47	94/18639	0.0106382978723404	4.21887732005432	0.211737447214244	0.286157275910204
GO:0005261	monoatomic cation channel activity	2/47	341/18639	0.00586510263929619	2.32594995944344	0.212310236965635	0.286157275910204
GO:0008170	N-methyltransferase activity	1/47	98/18639	0.0102040816326531	4.04667824576639	0.21969877597022	0.292522066191644
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	2/47	349/18639	0.00573065902578797	2.27263305492898	0.219728556632433	0.292522066191644
GO:0008238	exopeptidase activity	1/47	102/18639	0.00980392156862745	3.88798498122653	0.227581390432039	0.301129034900929
GO:0005253	monoatomic anion channel activity	1/47	103/18639	0.00970873786407767	3.85023755422433	0.229539834336106	0.301879660914758
GO:0022853	active monoatomic ion transmembrane transporter activity	1/47	118/18639	0.00847457627118644	3.36080057699243	0.25833982766056	0.337709292785189
GO:0004175	endopeptidase activity	2/47	405/18639	0.00493827160493827	1.95839243498818	0.272127828615878	0.353603226405063
GO:0004857	enzyme inhibitor activity	2/47	416/18639	0.00480769230769231	1.90660801963993	0.282455782539385	0.363885155708082
GO:0016887	ATP hydrolysis activity	2/47	417/18639	0.00479616306954436	1.90203581815399	0.283394430021502	0.363885155708082
GO:0099094	ligand-gated monoatomic cation channel activity	1/47	136/18639	0.00735294117647059	2.9159887359199	0.291511246946597	0.372105532867127
GO:0016922	nuclear receptor binding	1/47	137/18639	0.0072992700729927	2.89470414660662	0.293310899510695	0.372213246747491
GO:0020037	heme binding	1/47	142/18639	0.00704225352112676	2.79277794426131	0.302242264680493	0.381317275788762
GO:0008194	UDP-glycosyltransferase activity	1/47	145/18639	0.00689655172413793	2.73499633162142	0.307547955123837	0.385768244288281
GO:0008509	monoatomic anion transmembrane transporter activity	1/47	149/18639	0.00671140939597315	2.66157361130944	0.31456082677375	0.392297123045424
GO:0046906	tetrapyrrole binding	1/47	152/18639	0.00657894736842105	2.60904255319149	0.319774816188163	0.395567600964906
GO:0022804	active transmembrane transporter activity	2/47	457/18639	0.00437636761487965	1.73555565901578	0.320829021980753	0.395567600964906
GO:0005506	iron ion binding	1/47	154/18639	0.00649350649350649	2.57515888366952	0.32322922267113	0.396275374687205
GO:0140375	immune receptor activity	1/47	156/18639	0.00641025641025641	2.54214402618658	0.32666645793656	0.398239445911425
GO:0008083	growth factor activity	1/47	162/18639	0.00617283950617284	2.44799054373522	0.336875969528156	0.408391538478268
GO:0015103	inorganic anion transmembrane transporter activity	1/47	165/18639	0.00606060606060606	2.40348162475822	0.3419237525883	0.412208079509228
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	1/47	167/18639	0.00598802395209581	2.37469741368327	0.345268028265454	0.413940122285102
GO:0140297	DNA-binding transcription factor binding	2/47	488/18639	0.00409836065573771	1.62530519707011	0.349563873703426	0.416787695569469
GO:0005319	lipid transporter activity	1/47	178/18639	0.00561797752808989	2.22794644991633	0.363366347316936	0.430877034796585
GO:0016853	isomerase activity	1/47	180/18639	0.00555555555555556	2.2031914893617	0.36660392935652	0.431908204381882
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	1/47	181/18639	0.00552486187845304	2.1910191606912	0.368216671938471	0.431908204381882
GO:0015276	ligand-gated monoatomic ion channel activity	1/47	186/18639	0.00537634408602151	2.13212079615649	0.376220292672525	0.435113258021312
GO:0008234	cysteine-type peptidase activity	1/47	187/18639	0.0053475935828877	2.12071908066902	0.377809066652061	0.435113258021312
GO:0022834	ligand-gated channel activity	1/47	188/18639	0.00531914893617021	2.10943866002716	0.379393879890049	0.435113258021312
GO:0046943	carboxylic acid transmembrane transporter activity	1/47	188/18639	0.00531914893617021	2.10943866002716	0.379393879890049	0.435113258021312
GO:0005342	organic acid transmembrane transporter activity	1/47	189/18639	0.00529100529100529	2.09827760891591	0.38097474204631	0.435113258021312
GO:0016758	hexosyltransferase activity	1/47	197/18639	0.0050761421319797	2.01306836591425	0.393480551955369	0.447043349603744
GO:0003714	transcription corepressor activity	1/47	204/18639	0.00490196078431373	1.94399249061327	0.40422004322635	0.456852861354781
GO:0033218	amide binding	1/47	247/18639	0.00404858299595142	1.60556464811784	0.466223296171675	0.524199250099759
GO:0019887	protein kinase regulator activity	1/47	255/18639	0.00392156862745098	1.55519399249061	0.477040587865876	0.533596946221108
GO:0016757	glycosyltransferase activity	1/47	267/18639	0.00374531835205993	1.48529763327755	0.492865367813041	0.545757053544049
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	1/47	268/18639	0.00373134328358209	1.4797554779295	0.494162740320813	0.545757053544049
GO:0008514	organic anion transmembrane transporter activity	1/47	269/18639	0.00371747211895911	1.47425452819742	0.495456864277317	0.545757053544049
GO:0001217	DNA-binding transcription repressor activity	1/47	278/18639	0.00359712230215827	1.42652686361549	0.506959101846172	0.55560669242737
GO:0031267	small GTPase binding	1/47	283/18639	0.00353356890459364	1.40132320878129	0.51323792365571	0.559661454438638
GO:0019207	kinase regulator activity	1/47	287/18639	0.00348432055749129	1.38179257172511	0.518204573455003	0.562251962198678
GO:0001664	G protein-coupled receptor binding	1/47	297/18639	0.00336700336700337	1.33526756931012	0.530405215831785	0.572626526544763
GO:0051020	GTPase binding	1/47	315/18639	0.00317460317460317	1.25896656534954	0.551608886643833	0.592569942582732
GO:0030371	translation repressor activity	1/47	329/18639	0.00303951367781155	1.20539352001552	0.567450066043364	0.605970270639265
GO:0003924	GTPase activity	1/47	331/18639	0.00302114803625378	1.19811017548371	0.569667904195438	0.605970270639265
GO:0140097	catalytic activity, acting on DNA	1/47	336/18639	0.00297619047619048	1.1802811550152	0.575163921314767	0.608832053294168
GO:0061630	ubiquitin protein ligase activity	1/47	353/18639	0.0028328611898017	1.12344041950455	0.593341378830193	0.625024656340543
GO:0045182	translation regulator activity	1/47	356/18639	0.00280898876404494	1.11397322495816	0.596469167040114	0.625284102645916
GO:0046982	protein heterodimerization activity	1/47	369/18639	0.002710027100271	1.0747275557862	0.60975301010168	0.636136553808003
GO:0061659	ubiquitin-like protein ligase activity	1/47	372/18639	0.00268817204301075	1.06606039807824	0.612757191320625	0.636212012041032
GO:0004984	olfactory receptor activity	1/47	419/18639	0.00238663484486874	0.946478444117199	0.656971097885686	0.678870134481876
GO:0004842	ubiquitin-protein transferase activity	1/47	449/18639	0.0022271714922049	0.883239349855471	0.682567428968072	0.701976929317875
GO:0019787	ubiquitin-like protein transferase activity	1/47	479/18639	0.00208768267223382	0.827921645271621	0.706291444132618	0.718598699437561
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	1/47	484/18639	0.00206611570247934	0.81936873571303	0.710072979842407	0.718598699437561
GO:0030695	GTPase regulator activity	1/47	489/18639	0.00204498977505112	0.810990732280381	0.713806850628813	0.718598699437561
GO:0060589	nucleoside-triphosphatase regulator activity	1/47	490/18639	0.00204081632653061	0.809335649153278	0.714547956855835	0.718598699437561
GO:0001216	DNA-binding transcription activator activity	1/47	491/18639	0.00203665987780041	0.807687307708974	0.715287184693609	0.718598699437561
GO:0016755	aminoacyltransferase activity	1/47	496/18639	0.00201612903225806	0.799545298558682	0.718955310667762	0.718955310667762