category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Organismal Systems Immune system hsa04612 Antigen processing and presentation 2/30 82/9376 7.62276422764228 B2M/TAPBP 3.41254403095488 Cellular Processes Cell motility hsa04820 Cytoskeleton in muscle cells 3/30 233/9376 4.02403433476395 FBLN1/BGN/CSRP2 2.64821777143799 Environmental Information Processing Signaling molecules and interaction hsa04061 Viral protein interaction with cytokine and cytokine receptor 2/30 100/9376 6.25066666666667 TNFSF10/ACKR3 2.99066284790297 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 3/30 298/9376 3.14630872483221 TNFSF10/ACKR3/EBI3 2.13323456041268 Cellular Processes Cell growth and death hsa04210 Apoptosis 2/30 137/9376 4.5625304136253 TNFSF10/CTSH 2.37979615157208 Metabolism Glycan biosynthesis and metabolism hsa00601 Glycosphingolipid biosynthesis - lacto and neolacto series 1/30 28/9376 11.1619047619048 B3GNT3 3.0509013239818 Metabolism Metabolism of cofactors and vitamins hsa00790 Folate biosynthesis 1/30 28/9376 11.1619047619048 DHFR 3.0509013239818 Metabolism Global and overview maps hsa01240 Biosynthesis of cofactors 2/30 154/9376 4.05887445887446 DHFR/NAPRT 2.16841714223013 Human Diseases Drug resistance: antineoplastic hsa01523 Antifolate resistance 1/30 30/9376 10.4177777777778 DHFR 2.92704604843909 NA NA hsa04981 Folate transport and metabolism 1/30 31/9376 10.0817204301075 DHFR 2.86941060986248 Metabolism Glycan biosynthesis and metabolism hsa00512 Mucin type O-glycan biosynthesis 1/30 36/9376 8.68148148148148 B3GNT3 2.61611106315415 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 2/30 180/9376 3.47259259259259 B2M/TAPBP 1.89767882811546 Metabolism Metabolism of cofactors and vitamins hsa00760 Nicotinate and nicotinamide metabolism 1/30 38/9376 8.22456140350877 NAPRT 2.5281901056502 Organismal Systems Development and regeneration hsa04360 Axon guidance 2/30 184/9376 3.39710144927536 EFNA1/SEMA4C 1.86047438639036 Metabolism Metabolism of cofactors and vitamins hsa00670 One carbon pool by folate 1/30 39/9376 8.01367521367521 DHFR 2.48660986465192 Metabolism Glycan biosynthesis and metabolism hsa00513 Various types of N-glycan biosynthesis 1/30 44/9376 7.1030303030303 TUSC3 2.29888833578874 Organismal Systems Excretory system hsa04962 Vasopressin-regulated water reabsorption 1/30 44/9376 7.1030303030303 DYNLL1 2.29888833578874 Genetic Information Processing Folding, sorting and degradation hsa03050 Proteasome 1/30 46/9376 6.79420289855072 PSMB8 2.23185086027436 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 2/30 205/9376 3.04910569105691 B2M/TAPBP 1.68060758977377 NA NA hsa03272 Virion - Hepatitis viruses 1/30 48/9376 6.51111111111111 CD81 2.16869707763848 Human Diseases Infectious disease: parasitic hsa05144 Malaria 1/30 50/9376 6.25066666666667 CD81 2.10904148406304 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 2/30 214/9376 2.9208722741433 B2M/TAPBP 1.6104365112197 Organismal Systems Digestive system hsa04979 Cholesterol metabolism 1/30 52/9376 6.01025641025641 LPL 2.05255058441948 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 2/30 227/9376 2.75359765051395 B2M/TAPBP 1.51526798329866 Metabolism Glycan biosynthesis and metabolism hsa00510 N-Glycan biosynthesis 1/30 56/9376 5.58095238095238 TUSC3 1.94793836796115 Environmental Information Processing Signal transduction hsa04340 Hedgehog signaling pathway 1/30 56/9376 5.58095238095238 SCUBE2 1.94793836796115 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 2/30 248/9376 2.52043010752688 TNFSF10/DYNLL1 1.37479474311499 Metabolism Lipid metabolism hsa00561 Glycerolipid metabolism 1/30 65/9376 4.80820512820513 LPL 1.74546934447167 Organismal Systems Endocrine system hsa04929 GnRH secretion 1/30 65/9376 4.80820512820513 KISS1R 1.74546934447167 Cellular Processes Transport and catabolism hsa04142 Lysosome biogenesis 2/30 250/9376 2.50026666666667 SLC15A3/CTSH 1.36217093514119 Organismal Systems Endocrine system hsa03320 PPAR signaling pathway 1/30 76/9376 4.11228070175439 LPL 1.54339631466192 Human Diseases Infectious disease: bacterial hsa05133 Pertussis 1/30 78/9376 4.00683760683761 C2 1.51076140331381 Organismal Systems Immune system hsa04610 Complement and coagulation cascades 1/30 88/9376 3.55151515151515 C2 1.36242235660326 NA NA hsa04517 IgSF CAM signaling 2/30 299/9376 2.09052396878484 DYNLL1/PTPRF 1.08575795278512 Organismal Systems Immune system hsa04662 B cell receptor signaling pathway 1/30 91/9376 3.43443223443223 CD81 1.32208935738486 Cellular Processes Cellular community - eukaryotes hsa04520 Adherens junction 1/30 93/9376 3.36057347670251 PTPRF 1.29612891523851 Human Diseases Infectious disease: bacterial hsa05150 Staphylococcus aureus infection 1/30 99/9376 3.15690235690236 C2 1.22229963261595 Organismal Systems Digestive system hsa04974 Protein digestion and absorption 1/30 103/9376 3.03430420711974 COL17A1 1.17613657836761 Organismal Systems Immune system hsa04659 Th17 cell differentiation 1/30 109/9376 2.86727828746177 EBI3 1.11092845800031 Human Diseases Endocrine and metabolic disease hsa04931 Insulin resistance 1/30 109/9376 2.86727828746177 PTPRF 1.11092845800031 Environmental Information Processing Signal transduction hsa04071 Sphingolipid signaling pathway 1/30 125/9376 2.50026666666667 SPTSSA 0.956670766822138 Environmental Information Processing Signal transduction hsa04068 FoxO signaling pathway 1/30 133/9376 2.34987468671679 TNFSF10 0.88827241319952 Organismal Systems Immune system hsa04650 Natural killer cell mediated cytotoxicity 1/30 133/9376 2.34987468671679 TNFSF10 0.88827241319952 Organismal Systems Endocrine system hsa04910 Insulin signaling pathway 1/30 138/9376 2.26473429951691 PTPRF 0.847975370286038 Human Diseases Immune disease hsa05322 Systemic lupus erythematosus 1/30 143/9376 2.18554778554779 C2 0.809373613556441 Human Diseases Endocrine and metabolic disease hsa04936 Alcoholic liver disease 1/30 144/9376 2.17037037037037 C2 0.801844295378836 Human Diseases Infectious disease: viral hsa05160 Hepatitis C 1/30 156/9376 2.0034188034188 CD81 0.715999058165182 Environmental Information Processing Signaling molecules and interaction hsa04514 Cell adhesion molecule (CAM) interaction 1/30 160/9376 1.95333333333333 PTPRF 0.689075666621653 Cellular Processes Cell growth and death hsa04217 Necroptosis 1/30 168/9376 1.86031746031746 TNFSF10 0.637476383054397 Human Diseases Infectious disease: viral hsa05164 Influenza A 1/30 173/9376 1.80655105973025 TNFSF10 0.606629580977787 Genetic Information Processing Folding, sorting and degradation hsa04141 Protein processing in endoplasmic reticulum 1/30 174/9376 1.79616858237548 TUSC3 0.600581461953347 Environmental Information Processing Signal transduction hsa04310 Wnt signaling pathway 1/30 178/9376 1.75580524344569 NOTUM 0.576775197122135 Cellular Processes Cell motility hsa04814 Motor proteins 1/30 194/9376 1.61099656357388 DYNLL1 0.487196731016889 Human Diseases Infectious disease: bacterial hsa05130 Pathogenic Escherichia coli infection 1/30 200/9376 1.56266666666667 TNFSF10 0.455693527605604 Human Diseases Cancer: overview hsa05202 Transcriptional misregulation in cancer 1/30 201/9376 1.55489220563847 ASPSCR1 0.450543775386113 Environmental Information Processing Signal transduction hsa04015 Rap1 signaling pathway 1/30 212/9376 1.47421383647799 EFNA1 0.395669877911856 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 1/30 216/9376 1.44691358024691 TNFSF10 0.376474935546256 NA NA hsa04382 Cornified envelope formation 1/30 217/9376 1.44024577572965 COL17A1 0.371735820802104 NA NA hsa04081 Hormone signaling 1/30 219/9376 1.42709284627093 GUCA2A 0.362327355856363 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 1/30 224/9376 1.3952380952381 B2M 0.339201823503888 Environmental Information Processing Signal transduction hsa04014 Ras signaling pathway 1/30 238/9376 1.31316526610644 EFNA1 0.277248922078312 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 1/30 238/9376 1.31316526610644 C2 0.277248922078312 Environmental Information Processing Signal transduction hsa04010 MAPK signaling pathway 1/30 300/9376 1.04177777777778 EFNA1 0.0416669869353107 Human Diseases Cancer: overview hsa05206 MicroRNAs in cancer 1/30 323/9376 0.967595459236326 EFNA1 -0.0335771823482218 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 1/30 362/9376 0.863351749539595 EFNA1 -0.150221799927513 Environmental Information Processing Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction 1/30 370/9376 0.844684684684685 KISS1R -0.172696108208126 Human Diseases Neurodegenerative disease hsa05010 Alzheimer disease 1/30 388/9376 0.805498281786942 LPL -0.221687471682786