category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Metabolism Metabolism of cofactors and vitamins hsa00790 Folate biosynthesis 1/5 28/9376 66.9714285714286 DHFR 8.07519881774149 Human Diseases Drug resistance: antineoplastic hsa01523 Antifolate resistance 1/5 30/9376 62.5066666666667 DHFR 7.79377029378732 NA NA hsa04981 Folate transport and metabolism 1/5 31/9376 60.4903225806452 DHFR 7.6632887396459 Human Diseases Immune disease hsa05310 Asthma 1/5 32/9376 58.6 PRG2 7.53891295831894 Metabolism Metabolism of cofactors and vitamins hsa00670 One carbon pool by folate 1/5 39/9376 48.0820512820513 DHFR 6.80552559340531 Cellular Processes Cell growth and death hsa04216 Ferroptosis 1/5 42/9376 44.647619047619 FTH1 6.54830616416175 Metabolism Metabolism of cofactors and vitamins hsa00860 Porphyrin metabolism 1/5 46/9376 40.7652173913043 FTH1 6.24480851946727 Organismal Systems Digestive system hsa04978 Mineral absorption 1/5 61/9376 30.7409836065574 FTH1 5.38277822535598 Metabolism Metabolism of cofactors and vitamins hsa00830 Retinol metabolism 1/5 68/9376 27.5764705882353 ALDH1A1 5.08043905207262 Human Diseases Infectious disease: bacterial hsa05100 Bacterial invasion of epithelial cells 1/5 78/9376 24.0410256410256 FN1 4.71989143276643 Environmental Information Processing Signaling molecules and interaction hsa04512 ECM-receptor interaction 1/5 89/9376 21.0696629213483 FN1 4.39415154116153 Human Diseases Cancer: specific types hsa05222 Small cell lung cancer 1/5 93/9376 20.1634408602151 FN1 4.28991276818366 Human Diseases Endocrine and metabolic disease hsa04933 AGE-RAGE signaling pathway in diabetic complications 1/5 101/9376 18.5663366336634 FN1 4.09979933160897 Human Diseases Infectious disease: parasitic hsa05146 Amoebiasis 1/5 103/9376 18.2058252427184 FN1 4.0556611389408 Human Diseases Infectious disease: bacterial hsa05135 Yersinia infection 1/5 138/9376 13.5884057971014 FN1 3.44111328249538 Metabolism Global and overview maps hsa01240 Biosynthesis of cofactors 1/5 154/9376 12.1766233766234 DHFR 3.23024966026996 NA NA hsa04518 Integrin signaling 1/5 154/9376 12.1766233766234 FN1 3.23024966026996 Cellular Processes Cell growth and death hsa04217 Necroptosis 1/5 168/9376 11.1619047619048 FTH1 3.06990387710429 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 1/5 203/9376 9.23743842364532 FN1 2.74070425984643 Human Diseases Cancer: overview hsa05205 Proteoglycans in cancer 1/5 204/9376 9.1921568627451 FN1 2.73249258219407 Cellular Processes Cell motility hsa04810 Regulation of actin cytoskeleton 1/5 232/9376 8.08275862068966 FN1 2.523225102058 Cellular Processes Cell motility hsa04820 Cytoskeleton in muscle cells 1/5 233/9376 8.0480686695279 FN1 2.51640997948425 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 1/5 333/9376 5.63123123123123 FN1 1.98765034329943 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 1/5 362/9376 5.18011049723757 FN1 1.87353125219571