category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	18/152	248/9376	4.47707979626486	LY96/GAPDH/TXN/NAIP/IL1B/MYL12A/CD14/CXCL8/TLR5/RAF1/RHOH/TUBA1B/CYTH4/CASP4/NFKBIA/TNFRSF1A/TAB2/SNX18	7.12361545158693
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	9/152	56/9376	9.91353383458647	NAIP/IL1B/CXCL1/CR1/CD14/CXCL8/TLR5/HSPA6/NFKBIA	8.58783634573653
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	16/152	227/9376	4.3477857639694	CREB5/GNG10/IL1B/HLA-A/CXCR2/B2M/CXCL8/RAC2/RAF1/CXCR4/IL1R1/GNG5/NFKBIA/TNFRSF1A/PXN/CCR1	6.55437911605555
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	11/152	105/9376	6.46215538847118	LY96/IL1B/CXCL1/BCL2A1/CD14/CXCL8/TNFSF13B/IL1R1/NFKBIA/TNFRSF1A/TAB2	7.22508889548521
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	7/152	42/9376	10.280701754386	FTL/FTH1/SAT1/MAP1LC3B/ACSL1/PCBP2/PCBP1	7.73783292677845
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	13/152	187/9376	4.28820714888826	TXN/NAIP/IL1B/CXCL1/CXCL8/MFN2/CARD16/CYBA/MAP1LC3B/ERBIN/CASP4/NFKBIA/TAB2	5.83033664487121
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	14/152	216/9376	3.99805068226121	LY96/DDIT3/IL1B/CXCL1/CD14/CXCL8/HSPA5/CYBA/HSPA6/NFKBIA/TNFRSF1A/TAB2/NCF4/LDLR	5.72223769763459
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	13/152	193/9376	4.15489500954459	GNG10/CXCL1/CXCR2/CXCL8/RAC2/RAF1/CXCR4/GNG5/NFKBIA/PXN/PRKCZ/CXCR1/CCR1	5.68485063579998
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	11/152	142/9376	4.77835433654559	FCGR3B/IL1B/CYBA/SPI1/IL1R1/FCGR1A/NFKBIA/TNFRSF1A/TAB2/NCF4/JUNB	5.82370953741612
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	8/152	78/9376	6.32658569500675	FCGR3B/IL1B/CR1/CYBA/FCGR1A/NFKBIA/TAB2/NCF4	6.0638609487029
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	14/152	253/9376	3.41335552319534	NAIP/IL1B/MYL12A/CD14/CXCL8/TLR5/MAP1LC3B/CYTH4/IL1R1/CASP4/NFKBIA/TNFRSF1A/TAB2/PXN	4.99528777693257
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	12/152	196/9376	3.7765843179377	GNG10/CXCL1/ZFP36/CLEC2B/HLA-A/CXCL8/RAF1/MAP1LC3B/GNG5/NFKBIA/TNFRSF1A/CCR1	5.04272571489127
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	12/152	200/9376	3.70105263157895	GAPDH/NAIP/IL1B/CXCL8/TLR5/TUBA1B/CYTH4/IL1R1/CASP4/NFKBIA/TNFRSF1A/TAB2	4.95643171391535
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	7/152	71/9376	6.0815418828762	CXCL1/CXCR2/CXCL8/NFKBIA/CXCR1/ATP6V0C/ATP6V0E1	5.51714350096082
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	13/152	250/9376	3.20757894736842	RAB31/HLA-A/CXCR2/IGF2R/SH3GLB1/CXCR4/HSPA6/ZFYVE16/CYTH4/PRKCZ/LDLR/CXCR1/WASHC2C	4.54144230151326
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	10/152	155/9376	3.97962648556876	FCGR3B/LAMP1/HLA-A/CD14/CYBA/TUBA1B/FCGR1A/NCF4/ATP6V0C/ATP6V0E1	4.80160520783001
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	11/152	214/9376	3.1706837186424	GNG10/HLA-A/B2M/RAC2/RAF1/CXCR4/GNG5/NFKBIA/TNFRSF1A/TAB2/PXN	4.1234057935561
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	10/152	181/9376	3.40796743239314	FCGR3B/IL1B/LAMP1/CR1/CD14/RAF1/CLEC4E/FCGR1A/TNFRSF1A/ATP6V0C	4.19915411822591
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	7/152	94/9376	4.59350503919373	S100A9/IL1B/CXCL1/S100A8/CXCL8/NFKBIA/TAB2	4.49478774397447
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	13/152	298/9376	2.69092193571176	OSM/IL1B/CXCL1/CXCR2/CXCL8/CXCR4/TNFSF13B/IL1R1/TNFRSF1A/IL13RA1/CXCR1/CSF2RB/CCR1	3.80788992740574
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	7/152	100/9376	4.31789473684211	CXCL1/CXCR2/CXCL8/CXCR4/TNFRSF1A/CXCR1/CCR1	4.28183589502377
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	8/152	137/9376	3.60199769496735	DDIT3/BCL2A1/RAF1/TUBA1B/NFKBIA/TNFRSF1A/CSF2RB/LMNB1	3.93824284406086
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	7/152	109/9376	3.96137131820377	LY96/IL1B/CD14/CXCL8/TLR5/NFKBIA/TAB2	3.99194287876253
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	8/152	142/9376	3.47516679021497	DUSP1/TXN/IL1B/RAC2/CYBA/IL1R1/TNFRSF1A/PRKCZ	3.81506104481704
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	8/152	144/9376	3.42690058479532	LY96/IL1B/CXCL1/CD14/CXCL8/NFKBIA/TNFRSF1A/TAB2	3.76732527678868
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	7/152	116/9376	3.72232304900182	MYL12A/RAC2/RHOH/CYBA/CXCR4/PXN/NCF4	3.78713639360451
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	7/152	119/9376	3.62848297213622	CREB5/IL1B/CXCL1/NFKBIA/TNFRSF1A/TAB2/JUNB	3.70417334086586
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	6/152	95/9376	3.89584487534626	IL1B/CXCL1/CXCL8/TNFSF13B/ATP6V0C/ATP6V0E1	3.64156021139181
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	5/152	68/9376	4.53560371517028	BCL2A1/CD14/RAF1/SPI1/FCGR1A	3.75610423379754
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	6/152	103/9376	3.59325498211548	FN1/IL1B/CXCL1/CD14/CXCL8/IL1R1	3.39704647439692
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	7/152	138/9376	3.12890922959573	FN1/IL1B/CXCL8/RAC2/NFKBIA/TAB2/PXN	3.23411526365426
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	11/152	300/9376	2.26175438596491	DUSP1/DDIT3/IL1B/CD14/RAC2/RAF1/HSPA6/IL1R1/TNFRSF1A/TAB2/MAP3K2	2.8512545533318
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	6/152	112/9376	3.30451127819549	LY96/HSPA6/NFKBIA/TNFRSF1A/TAB2/LDLR	3.14946191548046
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	5/152	82/9376	3.7612323491656	HLA-A/B2M/HSPA5/HSPA6/IFI30	3.22371269775719
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	9/152	224/9376	2.47838345864662	CREB5/ZFP36/HLA-A/B2M/SPI1/IL1R1/NFKBIA/TNFRSF1A/TSPO	2.87475529873195
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	10/152	275/9376	2.24306220095694	CREB5/DDIT3/IL1B/HSPA5/RAC2/CYBA/PSMB3/HSPA6/TUBA1B/NCF4	2.68573052601905
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	8/152	195/9376	2.5306342780027	FCGR3B/CR1/RAC2/RAF1/CYBA/CASP4/FCGR1A/NCF4	2.77262753549198
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	8/152	201/9376	2.45509295627128	DDIT3/BCL2A1/BCL6/CD14/CXCL8/NFKBIZ/SPI1/FCGR1A	2.67690843197651
Organismal Systems	Digestive system	hsa04978	Mineral absorption	4/152	61/9376	4.04486626402071	FTL/FTH1/SLC8A1/ATP2B4	3.06259447928062
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	6/152	130/9376	2.84696356275304	CREB5/GNG10/RAF1/GNG5/NFKBIA/PRKCZ	2.72207974709788
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	5/152	98/9376	3.14715359828142	FCGR3B/RAC2/RAF1/FCGR1A/MARCKS	2.74281649070313
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	5/152	100/9376	3.08421052631579	IL1B/CR1/CD14/IL1R1/FCGR1A	2.68973193913295
Metabolism	Glycan biosynthesis and metabolism	hsa00604	Glycosphingolipid biosynthesis - ganglio series	2/152	15/9376	8.22456140350877	ST6GALNAC3/HEXA	3.59454378864752
Metabolism	Metabolism of cofactors and vitamins	hsa00730	Thiamine metabolism	2/152	15/9376	8.22456140350877	ALPL/TPK1	3.59454378864752
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	7/152	180/9376	2.39883040935673	IL1B/PPP1CB/HLA-A/B2M/NFKBIA/TNFRSF1A/TAB2	2.43248192140453
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	8/152	226/9376	2.18351187703773	HCAR3/CREB5/HCAR2/PPP1CB/RAC2/RAF1/NFKBIA/ATP2B4	2.31187356017893
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	5/152	109/9376	2.82955094157412	CREB5/PPP1CB/NFKBIA/TNFRSF1A/PRKCZ	2.46624352969692
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	8/152	232/9376	2.12704174228675	FN1/PPP1CB/MYL12A/RAC2/RAF1/CXCR4/PXN/TMSB4X	2.23132930940257
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	4/152	78/9376	3.16329284750337	LY96/IL1B/CD14/CXCL8	2.46272335970883
NA	NA	hsa03272	Virion - Hepatitis viruses	3/152	48/9376	3.85526315789474	LAMP1/CD63/LDLR	2.54577651975379
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	10/152	333/9376	1.85237869448396	FN1/CREB5/HLA-A/RAF1/TNFRSF1A/PXN/PRKCZ/ATP6V0C/ATP6V0E1/MAML3	2.03304139846578
Metabolism	Glycan biosynthesis and metabolism	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	2/152	21/9376	5.87468671679198	DSE/CSGALNACT1	2.87066322963184
Genetic Information Processing	Chromosome	hsa03083	Polycomb repressive complex	4/152	83/9376	2.97273303741281	MBD6/RYBP/PHC2/SFMBT2	2.31727288793521
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	7/152	203/9376	2.12704174228675	FN1/PPP1CB/MYL12A/RAC2/RAF1/ZYX/PXN	2.08391551744344
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	3/152	50/9376	3.70105263157895	IL1B/CR1/CXCL8	2.45820517373028
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	7/152	204/9376	2.11661506707946	FN1/PPP1CB/LUM/RAF1/TIMP3/CD63/PXN	2.06982834209984
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	7/152	205/9376	2.10629011553273	CREB5/HLA-A/NFKBIA/GTF2A1/PXN/GTF2H1/HNRNPK	2.05582148707082
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	8/152	250/9376	1.97389473684211	LAMP1/PPT1/IGF2R/CD63/CLN3/ATP6V0C/ATP6V0E1/HEXA	2.00350105729548
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	3/152	52/9376	3.5587044534413	VAPA/LDLR/TSPO	2.37502644366597
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	5/152	125/9376	2.46736842105263	NSMAF/RAC2/RAF1/TNFRSF1A/PRKCZ	2.12005740014901
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	4/152	89/9376	2.77232406859846	GNG10/GLUL/GNG5/SLC38A2	2.15649373571815
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	5/152	133/9376	2.3189552829442	CD48/FCGR3B/HLA-A/RAC2/RAF1	1.96651471611456
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	3/152	60/9376	3.08421052631579	RAC2/RAF1/PXN	2.07897973129381
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	5/152	138/9376	2.23493516399695	FLOT2/PPP1CB/RAF1/FLOT1/PRKCZ	1.87604178138884
Metabolism	Metabolism of cofactors and vitamins	hsa00790	Folate biosynthesis	2/152	28/9376	4.40601503759398	DHFR/ALPL	2.31693585228065
Organismal Systems	Excretory system	hsa04966	Collecting duct acid secretion	2/152	28/9376	4.40601503759398	ATP6V0C/ATP6V0E1	2.31693585228065
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	5/152	140/9376	2.20300751879699	GNG10/RAF1/MAP1LC3B/GNG5/SLC8A1	1.84093384613602
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	4/152	101/9376	2.44293903074518	FN1/IL1B/CXCL8/PRKCZ	1.87154163825344
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	2/152	30/9376	4.11228070175439	DHFR/IL1B	2.19166556363201
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	4/152	103/9376	2.39550332141032	IL1B/CXCL8/NFKBIA/TNFRSF1A	1.82804609292177
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	4/152	105/9376	2.34987468671679	IL1B/RAF1/CLEC4E/NFKBIA	1.78555239015708
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	5/152	149/9376	2.06993995054751	CXCR2/CXCL8/RAF1/CYTH4/CXCR1	1.68993524218448
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	3/152	70/9376	2.64360902255639	NFKBIA/ACSL1/TNFRSF1A	1.77179632921562
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	5/152	154/9376	2.00273410799727	KCNE1/CREB5/PPP1CB/SLC8A1/ATP2B4	1.61057656019884
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	6/152	205/9376	1.80539152759949	GAPDH/PPP1CB/RAC2/CYBA/PRKCZ/NCF4	1.49666094336068
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	4/152	115/9376	2.14553775743707	DUSP1/GNG10/RAF1/GNG5	1.58663551561474
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	4/152	115/9376	2.14553775743707	SGK1/CREB5/RAF1/MMP25	1.58663551561474
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	4/152	116/9376	2.12704174228675	GNG10/GLUL/GNG5/SLC38A2	1.56787446695227
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	2/152	37/9376	3.33428165007112	IDO2/IL1B	1.82621420006516
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	3/152	75/9376	2.46736842105263	CREB5/TG/HSPA5	1.63776943957071
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	5/152	163/9376	1.89215369712625	CREB5/CXCL8/RAF1/NFKBIA/TAB2	1.47496165916445
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	4/152	120/9376	2.05614035087719	ARHGDIB/IRAK3/RAF1/NFKBIA	1.49468050698638
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	5/152	166/9376	1.85795814838301	CREB5/PPP1CB/RAF1/SLC8A1/ATP2B4	1.43165415232436
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	5/152	168/9376	1.83583959899749	FTL/FTH1/IL1B/GLUL/TNFRSF1A	1.40327475775031
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	2/152	41/9376	3.00898587933248	CXCL8/RAF1	1.65485305660238
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	7/152	268/9376	1.61115475255302	DUSP1/TXN/DDIT3/HSPA5/MFN2/PSMB3/TUBA1B	1.303031349267
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	2/152	42/9376	2.93734335839599	IDO2/AOC1	1.61527001145011
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	5/152	173/9376	1.78278065104959	IL1B/CXCL8/RAF1/NFKBIA/TNFRSF1A	1.33397044531934
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	3/152	83/9376	2.22954977805961	IL1B/NFKBIA/PCBP1	1.44429190925952
Genetic Information Processing	Transcription	hsa03022	Basal transcription factors	2/152	44/9376	2.80382775119617	GTF2A1/GTF2H1	1.53950754719748
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	2/152	44/9376	2.80382775119617	IL1B/HLA-A	1.53950754719748
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	2/152	44/9376	2.80382775119617	CREB5/ARHGDIB	1.53950754719748
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	2/152	45/9376	2.74152046783626	IL1B/HLA-A	1.50320610265305
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	4/152	133/9376	1.85516422635536	CREB5/GNG10/PPP1CB/GNG5	1.27501899235631
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	2/152	46/9376	2.68192219679634	FTL/FTH1	1.46788415018291
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	3/152	89/9376	2.07924305144885	RAF1/TUBA1B/MAP3K2	1.31318020276464
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	5/152	184/9376	1.67620137299771	MYL12A/RAC2/RAF1/CXCR4/PRKCZ	1.18912562204842
Human Diseases	Infectious disease: viral	hsa05162	Measles	4/152	136/9376	1.81424148606811	IL1B/HSPA6/NFKBIA/TAB2	1.22781936791443
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	3/152	91/9376	2.03354540196645	RAC2/RAF1/NFKBIA	1.27176563751941
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	4/152	139/9376	1.77508519500189	CREB5/FKBP5/RAF1/HSPA6	1.18178685440562
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	2/152	50/9376	2.46736842105263	SAT1/AOC1	1.33543959944662
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	2/152	50/9376	2.46736842105263	CXCR4/TNFSF13B	1.33543959944662
Human Diseases	Substance dependence	hsa05034	Alcoholism	5/152	191/9376	1.61476990906586	CREB5/GNG10/PPP1CB/RAF1/GNG5	1.10188809378642
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	2/152	51/9376	2.41898864809082	ATP6V0C/ATP6V0E1	1.30432967158424
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	2/152	53/9376	2.32770605759682	SLC8A1/ATP2B4	1.24425620275421
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	3/152	98/9376	1.88829215896885	CREB5/LDLR/ATP2B4	1.13472197989569
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	3/152	99/9376	1.86921850079745	IL1B/PPP1CB/IL1R1	1.11606776689415
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	2/152	54/9376	2.28460038986355	TG/HLA-A	1.21522911255013
Metabolism	Glycan biosynthesis and metabolism	hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series	1/152	16/9376	3.85526315789474	HEXA	1.46729012110574
Metabolism	Global and overview maps	hsa01212	Fatty acid metabolism	2/152	57/9376	2.16435826408126	PPT1/ACSL1	1.13184560015602
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	4/152	154/9376	1.60218728639781	DHFR/IDO2/ALPL/TPK1	0.967224232811979
Metabolism	Metabolism of other amino acids	hsa00450	Selenocompound metabolism	1/152	17/9376	3.62848297213622	SEPHS2	1.39239575311828
Metabolism	Energy metabolism	hsa00910	Nitrogen metabolism	1/152	17/9376	3.62848297213622	GLUL	1.39239575311828
NA	NA	hsa03273	Virion - Lassa virus and SFTS virus	1/152	17/9376	3.62848297213622	LAMP1	1.39239575311828
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	3/152	106/9376	1.74577954319762	CREB5/RAF1/NFKBIA	0.991222877513726
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	4/152	156/9376	1.58164642375169	RAF1/NFKBIA/TNFRSF1A/LDLR	0.940380653670789
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	4/152	157/9376	1.57157224270868	PPP1CB/HLA-A/CXCL8/RAF1	0.927100539308061
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	4/152	157/9376	1.57157224270868	DDIT3/IL1B/CXCL8/TNFRSF1A	0.927100539308061
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	4/152	158/9376	1.5616255829447	SGK1/RAF1/TBC1D7/TNFRSF1A	0.913913008374854
Metabolism	Lipid metabolism	hsa00061	Fatty acid biosynthesis	1/152	18/9376	3.42690058479532	ACSL1	1.32295326809711
Metabolism	Glycan biosynthesis and metabolism	hsa00511	Other glycan degradation	1/152	18/9376	3.42690058479532	HEXA	1.32295326809711
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	3/152	109/9376	1.69773056494447	IL1B/IL1R1/NFKBIA	0.940544180631316
Metabolism	Glycan biosynthesis and metabolism	hsa00531	Glycosaminoglycan degradation	1/152	19/9376	3.24653739612188	HEXA	1.25825864536663
Metabolism	Glycan biosynthesis and metabolism	hsa00541	Biosynthesis of various nucleotide sugars	1/152	20/9376	3.08421052631579	NPL	1.19773092012126
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	2/152	65/9376	1.89797570850202	DGAT2/GK	0.932547342011096
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	2/152	65/9376	1.89797570850202	CREB5/LDLR	0.932547342011096
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	3/152	115/9376	1.6091533180778	CREB5/GNG10/GNG5	0.843712293760776
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	4/152	168/9376	1.46867167919799	OSM/RAF1/IL13RA1/CSF2RB	0.786843717239302
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	2/152	66/9376	1.86921850079745	IL1B/TLR5	0.909649057253147
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	4/152	169/9376	1.45998131423233	LAMP1/RAF1/SH3GLB1/MAP1LC3B	0.774590659177354
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	2/152	67/9376	1.84131971720346	PPP1CB/RAF1	0.887145263969575
Metabolism	Amino acid metabolism	hsa00340	Histidine metabolism	1/152	22/9376	2.80382775119617	AOC1	1.08731531893178
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	2/152	69/9376	1.78794813119756	RAC2/RAF1	0.843266996271434
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	2/152	69/9376	1.78794813119756	CREB5/PPP1CB	0.843266996271434
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	4/152	174/9376	1.41802782819117	DDIT3/PPP1R15A/HSPA5/HSPA6	0.714474097469828
Metabolism	Amino acid metabolism	hsa00220	Arginine biosynthesis	1/152	23/9376	2.68192219679634	GLUL	1.03667383649532
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	2/152	70/9376	1.76240601503759	HLA-A/RAC2	0.821867098730391
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	3/152	122/9376	1.51682484900777	CREB5/RAF1/JUNB	0.737575256897664
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	2/152	72/9376	1.71345029239766	CXCL8/NFKBIA	0.780086752372564
Organismal Systems	Immune system	hsa04611	Platelet activation	3/152	126/9376	1.46867167919799	PPP1CB/MYL12A/PRKCZ	0.679877865199331
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	5/152	238/9376	1.29588677576294	IL1B/CXCL8/NFKBIA/TNFRSF1A/TAB2	0.593521208166536
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	2/152	75/9376	1.64491228070175	GAPDH/GLUL	0.719803976549727
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	2/152	76/9376	1.62326869806094	GK/ACSL1	0.700306928545249
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	2/152	76/9376	1.62326869806094	HRH2/KCNJ15	0.700306928545249
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	2/152	77/9376	1.60218728639781	RAC2/RAF1	0.681093296787542
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	2/152	77/9376	1.60218728639781	RAF1/NFKBIA	0.681093296787542
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	2/152	78/9376	1.58164642375169	FN1/PXN	0.662154565211794
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	3/152	133/9376	1.39137316976652	SGK1/BCL6/RAF1	0.583523268598051
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	2/152	79/9376	1.5616255829447	ATP6V0C/ATP6V0E1	0.643482584672595
Metabolism	Lipid metabolism	hsa00062	Fatty acid elongation	1/152	28/9376	2.20300751879699	PPT1	0.818343788884997
Metabolism	Glycan biosynthesis and metabolism	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	1/152	28/9376	2.20300751879699	ST3GAL4	0.818343788884997
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	3/152	134/9376	1.38098978790259	PPP1CB/RAF1/ADM	0.570204364334338
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	7/152	362/9376	1.1927886013376	FN1/OSM/SGK1/CREB5/GNG10/RAF1/GNG5	0.480202753524715
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	9/152	480/9376	1.15657894736842	DDIT3/IL1B/HSPA5/RAF1/MFN2/PSMB3/MAP1LC3B/TUBA1B/TNFRSF1A	0.452068644826774
Metabolism	Carbohydrate metabolism	hsa00030	Pentose phosphate pathway	1/152	31/9376	1.98981324278438	RBKS	0.70858546422305
Metabolism	Carbohydrate metabolism	hsa00630	Glyoxylate and dicarboxylate metabolism	1/152	31/9376	1.98981324278438	GLUL	0.70858546422305
Genetic Information Processing	Folding, sorting and degradation	hsa03060	Protein export	1/152	31/9376	1.98981324278438	HSPA5	0.70858546422305
NA	NA	hsa04981	Folate transport and metabolism	1/152	31/9376	1.98981324278438	DHFR	0.70858546422305
NA	NA	hsa04082	Neuroactive ligand signaling	4/152	199/9376	1.23988362866966	GNG10/HRH2/GNG5/P2RY13	0.439060701632183
Cellular Processes	Cell growth and death	hsa04215	Apoptosis - multiple species	1/152	32/9376	1.92763157894737	TNFRSF1A	0.674732895540305
Human Diseases	Immune disease	hsa05310	Asthma	1/152	32/9376	1.92763157894737	PRG2	0.674732895540305
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	2/152	87/9376	1.41802782819117	RAC2/RAF1	0.502838038617915
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	2/152	88/9376	1.40191387559809	CR1/SERPINE2	0.486251571244638
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	4/152	205/9376	1.20359435173299	HLA-A/B2M/NFKBIA/TAB2	0.378339855940394
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	2/152	90/9376	1.37076023391813	RAF1/NFKBIA	0.453678133546209
Human Diseases	Substance dependence	hsa05032	Morphine addiction	2/152	91/9376	1.3556969346443	GNG10/GNG5	0.437680955273888
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	7/152	388/9376	1.11285946825827	GAPDH/DDIT3/IL1B/RAF1/PSMB3/TUBA1B/TNFRSF1A	0.29145406416717
Metabolism	Carbohydrate metabolism	hsa00040	Pentose and glucuronate interconversions	1/152	36/9376	1.71345029239766	FGGY	0.550540556572674
Metabolism	Carbohydrate metabolism	hsa00500	Starch and sucrose metabolism	1/152	36/9376	1.71345029239766	GYG1	0.550540556572674
Metabolism	Glycan biosynthesis and metabolism	hsa00512	Mucin type O-glycan biosynthesis	1/152	36/9376	1.71345029239766	ST6GALNAC3	0.550540556572674
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	2/152	93/9376	1.32654216185625	MYL12A/RAC2	0.406241556697938
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	2/152	93/9376	1.32654216185625	NFKBIA/MAML3	0.406241556697938
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	2/152	93/9376	1.32654216185625	RAF1/MAP3K2	0.406241556697938
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	2/152	93/9376	1.32654216185625	FN1/NFKBIA	0.406241556697938
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	4/152	212/9376	1.16385302879841	RAC2/RAF1/SIPA1L2/PRKCZ	0.309761649938944
Metabolism	Amino acid metabolism	hsa00250	Alanine, aspartate and glutamate metabolism	1/152	37/9376	1.66714082503556	GLUL	0.52193446668529
NA	NA	hsa04518	Integrin signaling	3/152	154/9376	1.20164046479836	FN1/RAC2/PXN	0.323871905425124
Metabolism	Carbohydrate metabolism	hsa00520	Amino sugar and nucleotide sugar metabolism	1/152	38/9376	1.62326869806094	HEXA	0.494183185756164
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	1/152	38/9376	1.62326869806094	SGK1	0.494183185756164
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	2/152	97/9376	1.27183939229517	GNG10/GNG5	0.345458159938168
NA	NA	hsa04382	Cornified envelope formation	4/152	217/9376	1.13703613873393	S100A9/S100A11/S100A8/S100A12	0.262173465923641
Metabolism	Metabolism of cofactors and vitamins	hsa00670	One carbon pool by folate	1/152	39/9376	1.58164642375169	DHFR	0.467235111383706
Human Diseases	Immune disease	hsa05330	Allograft rejection	1/152	39/9376	1.58164642375169	HLA-A	0.467235111383706
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	2/152	99/9376	1.2461456671983	FCGR3B/FCGR1A	0.316048548056263
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	2/152	99/9376	1.2461456671983	RAC2/RAF1	0.316048548056263
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	2/152	103/9376	1.19775166070516	SLC38A2/SLC8A1	0.259045711446622
Metabolism	Lipid metabolism	hsa00071	Fatty acid degradation	1/152	43/9376	1.43451652386781	ACSL1	0.366587520460618
Organismal Systems	Digestive system	hsa04975	Fat digestion and absorption	1/152	43/9376	1.43451652386781	DGAT2	0.366587520460618
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	2/152	105/9376	1.1749373433584	MFN2/MAP1LC3B	0.231399102920468
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	1/152	44/9376	1.40191387559809	HEXA	0.343020249242941
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	3/152	170/9376	1.08854489164087	MYL12A/TUBA1B/PRKCZ	0.1495547706783
Genetic Information Processing	Folding, sorting and degradation	hsa03050	Proteasome	1/152	46/9376	1.34096109839817	PSMB3	0.297571072622113
NA	NA	hsa04517	IgSF CAM signaling	5/152	299/9376	1.03150853722936	CD48/MYL12A/TUBA1B/PXN/MBP	0.0710788599057991
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	1/152	47/9376	1.31243001119821	PRKCZ	0.275633444168148
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	4/152	238/9376	1.03670942061035	GNG10/RAC2/RAF1/GNG5	0.0736356655871787
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	1/152	49/9376	1.25886143931257	CREB5	0.233207330822347
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	6/152	368/9376	1.00572082379863	DDIT3/HSPA5/PSMB3/MAP1LC3B/TUBA1B/TNFRSF1A	0.0143719625649002
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	1/152	52/9376	1.18623481781377	LDLR	0.17286584874784
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	2/152	122/9376	1.01121656600518	RAF1/NFKBIA	0.0160074763600495
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	4/152	254/9376	0.971404890178201	HRH2/CXCR4/SLC8A1/ATP2B4	-0.0593077404414797
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	1/152	55/9376	1.12153110047847	HEXA	0.11603401135825
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	1/152	59/9376	1.04549509366637	UPP1	0.0449987351559595
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	1/152	59/9376	1.04549509366637	RAF1	0.0449987351559595
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/152	60/9376	1.0280701754386	RAF1	0.027999727020792
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	1/152	62/9376	0.99490662139219	HSPA6	-0.00516513257199618
Environmental Information Processing	Signal transduction	hsa04330	Notch signaling pathway	1/152	62/9376	0.99490662139219	MAML3	-0.00516513257199618
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	1/152	63/9376	0.979114452798663	PTGDS	-0.0213510440495082
Genetic Information Processing	Replication and repair	hsa03420	Nucleotide excision repair	1/152	63/9376	0.979114452798663	GTF2H1	-0.0213510440495082
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/152	65/9376	0.948987854251012	RAF1	-0.0529760888608649
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	2/152	138/9376	0.89397406559878	ATP6V0C/ATP6V0E1	-0.161068442009295
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	1/152	67/9376	0.920659858601728	GAPDH	-0.083661691560156
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	2/152	142/9376	0.868791697553744	UBE2B/UBE2H	-0.202235940381137
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	2/152	143/9376	0.862716231137284	FCGR3B/FCGR1A	-0.212355532119119
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	1/152	70/9376	0.881203007518797	RAF1	-0.128062131754834
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	3/152	217/9376	0.852777104050449	CREB5/BCL6/RAF1	-0.281662466930354
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	1/152	71/9376	0.868791697553744	RAF1	-0.142455784051067
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	1/152	71/9376	0.868791697553744	RAF1	-0.142455784051067
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	1/152	73/9376	0.844989185291997	CXCR4	-0.170670988339556
Human Diseases	Cancer: specific types	hsa05218	Melanoma	1/152	73/9376	0.844989185291997	RAF1	-0.170670988339556
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	1/152	73/9376	0.844989185291997	RAF1	-0.170670988339556
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	2/152	149/9376	0.827975980219004	GNG10/GNG5	-0.27170632649186
Human Diseases	Cancer: specific types	hsa05214	Glioma	1/152	76/9376	0.811634349030471	RAF1	-0.211648316182564
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	3/152	227/9376	0.815209830744262	RAF1/CYBA/NFKBIA	-0.361786838111799
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	2/152	154/9376	0.801093643198906	PPP1CB/RAF1	-0.319480421961732
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	2/152	155/9376	0.795925297113752	CREB5/LDLR	-0.328862077482147
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	1/152	78/9376	0.790823211875843	IMPA2	-0.238129832036724
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	2/152	157/9376	0.785786121354341	PPP1CB/PRKCZ	-0.347458794497273
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/152	80/9376	0.771052631578947	RAF1	-0.2639856848374
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	3/152	233/9376	0.794217302913937	FN1/ZYX/LMNB1	-0.408310210793247
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	1/152	82/9376	0.752246469833119	UPP1	-0.289249907330143
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	1/152	83/9376	0.743183259353202	ACSL1	-0.301670048091855
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	1/152	85/9376	0.725696594427245	UPP1	-0.326104819587435
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/152	86/9376	0.717258261933905	RAF1	-0.338126397180692
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/152	86/9376	0.717258261933905	CREB5	-0.338126397180692
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	1/152	86/9376	0.717258261933905	SLC8A1	-0.338126397180692
Genetic Information Processing	Transcription	hsa03040	Spliceosome	3/152	243/9376	0.761533463287849	HSPA6/PCBP1/HNRNPK	-0.483472345314667
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	1/152	87/9376	0.709013914095584	SLC8A1	-0.350021847431573
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	1/152	89/9376	0.693081017149616	FN1	-0.373446863142383
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/152	90/9376	0.685380116959064	CREB5	-0.384982390927224
Organismal Systems	Digestive system	hsa04976	Bile secretion	1/152	90/9376	0.685380116959064	LDLR	-0.384982390927224
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	4/152	323/9376	0.763891152028679	RAF1/TIMP3/MARCKS/HNRNPK	-0.554325743525638
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/152	93/9376	0.663271080928127	ATP2B4	-0.418914603527336
NA	NA	hsa04519	Cadherin signaling	5/152	404/9376	0.763418447107869	PPP1CB/RAC2/RAF1/ERBIN/NFKBIA	-0.62398580957448
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/152	98/9376	0.629430719656283	IMPA2	-0.473372530911745
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	1/152	99/9376	0.623072833599149	RAF1	-0.48397067078162
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	1/152	99/9376	0.623072833599149	SLC8A1	-0.48397067078162
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/152	101/9376	0.610734757686295	RAF1	-0.504890431121459
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	1/152	102/9376	0.604747162022704	ATP2B4	-0.515215976865723
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	1/152	103/9376	0.59887583035258	PPP1CB	-0.525454479290952
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	1/152	105/9376	0.587468671679198	SLC8A1	-0.545677540697837
Cellular Processes	Cell motility	hsa04814	Motor proteins	2/152	194/9376	0.635919696147585	MYL12A/TUBA1B	-0.657774738678628
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/152	107/9376	0.576487948844073	CREB5	-0.5655734391202
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	1/152	108/9376	0.571150097465887	XPO6	-0.575402793401307
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	1/152	110/9376	0.560765550239234	GAPDH	-0.594832069407573
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	1/152	110/9376	0.560765550239234	ZFYVE16	-0.594832069407573
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	1/152	110/9376	0.560765550239234	RAF1	-0.594832069407573
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	1/152	116/9376	0.531760435571688	GAPDH	-0.651387459699976
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	4/152	370/9376	0.666856330014225	HRH2/P2RY13/TSPO/ADM	-0.83929423780788
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/152	122/9376	0.505608283002589	CREB5	-0.705560304177566
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/152	122/9376	0.505608283002589	RAF1	-0.705560304177566
NA	NA	hsa04081	Hormone signaling	2/152	219/9376	0.563326123527998	GNG10/GNG5	-0.839364209349954
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	3/152	308/9376	0.60082023239918	CREB5/PSMB3/TUBA1B	-0.914399349725323
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	1/152	138/9376	0.44698703279939	PPP1CB	-0.840105183142007
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	2/152	235/9376	0.524972004479283	CREB5/ACSL1	-0.946681885271917
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	1/152	144/9376	0.428362573099415	RAF1	-0.887363965797815
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	1/152	144/9376	0.428362573099415	PSMB3	-0.887363965797815
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	1/152	148/9376	0.41678520625889	RAF1	-0.918022618286294
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	1/152	150/9376	0.411228070175439	RAF1	-0.93311202434359
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	1/152	157/9376	0.392893060677171	SGK1	-0.984738461399941
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	1/152	158/9376	0.390406395736176	CDKN1C	-0.991969635424663
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	1/152	160/9376	0.385526315789474	HLA-A	-1.00632863713784
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	1/152	170/9376	0.362848297213622	RAF1	-1.07616684634944
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	1/152	178/9376	0.346540508574808	RAC2	-1.12987332087247
Genetic Information Processing	Translation	hsa03008	Ribosome biogenesis in eukaryotes	1/152	183/9376	0.337072188668392	NOP10	-1.16254812187013
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	1/152	449/9376	0.137381315203376	SLC8A1	-2.40456792190899