ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0051082	unfolded protein binding	31/633	121/18639	0.256198347107438	7.54388782264698	5.27897466113551e-19	5.06781567469009e-16
GO:0044183	protein folding chaperone	21/633	75/18639	0.28	8.24473933649289	3.85057610923126e-14	1.84827653243101e-11
GO:0140662	ATP-dependent protein folding chaperone	16/633	40/18639	0.4	11.7781990521327	7.65351420787561e-14	2.4491245465202e-11
GO:0031625	ubiquitin protein ligase binding	38/633	302/18639	0.125827814569536	3.70506261573711	3.34134187015317e-12	8.0192204883676e-10
GO:0044389	ubiquitin-like protein ligase binding	39/633	322/18639	0.12111801242236	3.5663801477731	5.72403079141267e-12	1.09901391195123e-09
GO:0031072	heat shock protein binding	23/633	131/18639	0.175572519083969	5.1698201946384	8.71998648541533e-11	1.39519783766645e-08
GO:0051087	protein-folding chaperone binding	22/633	134/18639	0.164179104477612	4.83433543184551	8.51023862677838e-10	1.16711844024389e-07
GO:0016887	ATP hydrolysis activity	36/633	417/18639	0.0863309352517986	2.54205734938116	3.14052905172951e-07	3.76863486207541e-05
GO:0045296	cadherin binding	31/633	334/18639	0.092814371257485	2.73296534892301	4.42623748519139e-07	4.72131998420415e-05
GO:0008135	translation factor activity, RNA binding	13/633	83/18639	0.156626506024096	4.61194541197967	4.20690880915893e-06	0.000403863245679257
GO:0180051	translation factor activity	13/633	84/18639	0.154761904761905	4.5570412999323	4.82483765508981e-06	0.000421076740807838
GO:0003743	translation initiation factor activity	10/633	51/18639	0.196078431372549	5.77362698633956	6.90385182127355e-06	0.000509822903724816
GO:0030544	Hsp70 protein binding	10/633	51/18639	0.196078431372549	5.77362698633956	6.90385182127355e-06	0.000509822903724816
GO:0004601	peroxidase activity	10/633	57/18639	0.175438596491228	5.16587677725119	1.94246372077641e-05	0.00133197512281811
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	10/633	59/18639	0.169491525423729	4.99076231022572	2.65884157731373e-05	0.00170165860948079
GO:0097718	disordered domain specific binding	7/633	28/18639	0.25	7.36137440758294	3.20162925571105e-05	0.00184241751948963
GO:0016209	antioxidant activity	12/633	86/18639	0.13953488372093	4.10867408795327	3.26261435742956e-05	0.00184241751948963
GO:0072542	protein phosphatase activator activity	6/633	21/18639	0.285714285714286	8.41299932295193	5.25490835026832e-05	0.00280261778680977
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	27/633	349/18639	0.0773638968481375	2.27801844131506	6.49448649298233e-05	0.00328142475434897
GO:0048156	tau protein binding	8/633	43/18639	0.186046511627907	5.47823211727102	8.57640514854116e-05	0.00411667447129976
GO:0042626	ATPase-coupled transmembrane transporter activity	12/633	98/18639	0.122448979591837	3.60557113840797	0.000119749956287649	0.00547428371600679
GO:0019211	phosphatase activator activity	6/633	25/18639	0.24	7.06691943127962	0.000152735820356319	0.00666483579736666
GO:0050750	low-density lipoprotein particle receptor binding	6/633	26/18639	0.230769230769231	6.79511483776887	0.000192895441855594	0.00805128800788568
GO:0003725	double-stranded RNA binding	10/633	75/18639	0.133333333333333	3.9260663507109	0.000215570146970129	0.00856327797791134
GO:0060590	ATPase regulator activity	8/633	49/18639	0.163265306122449	4.80742818454396	0.000223002030674775	0.00856327797791134
GO:0001671	ATPase activator activity	6/633	27/18639	0.222222222222222	6.5434439178515	0.000240941955069439	0.00889631834102543
GO:0019888	protein phosphatase regulator activity	12/633	107/18639	0.11214953271028	3.30229879966337	0.000277086948583849	0.00985198039409243
GO:0042277	peptide binding	20/633	249/18639	0.0803212851405622	2.36510021127163	0.000344503138238039	0.0118115361681613
GO:0008432	JUN kinase binding	4/633	11/18639	0.363636363636364	10.707453683757	0.000359351189206529	0.0118957635047679
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	8/633	54/18639	0.148148148148148	4.36229594523433	0.000443340889659424	0.0139667677662813
GO:0043024	ribosomal small subunit binding	5/633	20/18639	0.25	7.36137440758294	0.0004510102091195	0.0139667677662813
GO:0001540	amyloid-beta binding	10/633	83/18639	0.120481927710843	3.54765031690744	0.000496307110831272	0.0148892133249382
GO:0070325	lipoprotein particle receptor binding	6/633	31/18639	0.193548387096774	5.6991285736126	0.00053397075330751	0.015533694641673
GO:0019208	phosphatase regulator activity	12/633	117/18639	0.102564102564103	3.02005103900839	0.000630413336188139	0.0177999059629592
GO:0140297	DNA-binding transcription factor binding	31/633	488/18639	0.0635245901639344	1.87051316913993	0.000662507027015248	0.0181716213124182
GO:0015631	tubulin binding	26/633	385/18639	0.0675324675324675	1.98852711269773	0.000729204622424838	0.0191341400821799
GO:0031994	insulin-like growth factor I binding	4/633	13/18639	0.307692307692308	9.06015311702516	0.000737461649000682	0.0191341400821799
GO:0016922	nuclear receptor binding	13/633	137/18639	0.0948905109489051	2.79409831528695	0.000799936220773726	0.0202089150511257
GO:0019207	kinase regulator activity	21/633	287/18639	0.0731707317073171	2.15454860709745	0.000845492062534875	0.0204409240171312
GO:0003697	single-stranded DNA binding	12/633	121/18639	0.0991735537190083	2.92021464102464	0.000851705167380467	0.0204409240171312
GO:0044548	S100 protein binding	4/633	14/18639	0.285714285714286	8.41299932295193	0.00100485336387478	0.0229680768885665
GO:0098847	sequence-specific single stranded DNA binding	4/633	14/18639	0.285714285714286	8.41299932295193	0.00100485336387478	0.0229680768885665
GO:0042625	ATPase-coupled ion transmembrane transporter activity	5/633	24/18639	0.208333333333333	6.13447867298578	0.0011050048580474	0.0230782101728898
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	5/633	24/18639	0.208333333333333	6.13447867298578	0.0011050048580474	0.0230782101728898
GO:0046961	proton-transporting ATPase activity, rotational mechanism	5/633	24/18639	0.208333333333333	6.13447867298578	0.0011050048580474	0.0230782101728898
GO:0140693	molecular condensate scaffold activity	7/633	48/18639	0.145833333333333	4.29413507109005	0.00110583090411764	0.0230782101728898
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	6/633	36/18639	0.166666666666667	4.90758293838863	0.00122333030077766	0.0239672875254399
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	6/633	36/18639	0.166666666666667	4.90758293838863	0.00122333030077766	0.0239672875254399
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	6/633	36/18639	0.166666666666667	4.90758293838863	0.00122333030077766	0.0239672875254399
GO:0031386	protein tag activity	4/633	15/18639	0.266666666666667	7.8521327014218	0.00133367697930976	0.0251045078458309
GO:0141047	molecular tag activity	4/633	15/18639	0.266666666666667	7.8521327014218	0.00133367697930976	0.0251045078458309
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	12/633	128/18639	0.09375	2.7605154028436	0.00139394469943547	0.0257343636818856
GO:0015399	primary active transmembrane transporter activity	14/633	166/18639	0.0843373493975904	2.48335522183521	0.00161846326408446	0.0291049583562967
GO:0042162	telomeric DNA binding	6/633	38/18639	0.157894736842105	4.64928909952607	0.00163715390754169	0.0291049583562967
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	6/633	39/18639	0.153846153846154	4.53007655851258	0.00188013731089926	0.0328169421538779
GO:0023026	MHC class II protein complex binding	5/633	27/18639	0.185185185185185	5.45286993154292	0.00192964683231876	0.0330796599826073
GO:0033218	amide binding	18/633	247/18639	0.0728744939271255	2.1458257382428	0.00201672770716338	0.0339659403311728
GO:0051787	misfolded protein binding	4/633	17/18639	0.235294117647059	6.92835238360747	0.00220311220805937	0.0364653055127068
GO:0016859	cis-trans isomerase activity	6/633	42/18639	0.142857142857143	4.20649966147596	0.00277418469193087	0.0436593000697318
GO:0048487	beta-tubulin binding	6/633	42/18639	0.142857142857143	4.20649966147596	0.00277418469193087	0.0436593000697318
GO:0051879	Hsp90 protein binding	6/633	42/18639	0.142857142857143	4.20649966147596	0.00277418469193087	0.0436593000697318
GO:0019887	protein kinase regulator activity	18/633	255/18639	0.0705882352941176	2.07850571508224	0.00284745494433032	0.0440896249444695
GO:0005520	insulin-like growth factor binding	4/633	19/18639	0.210526315789474	6.19905213270142	0.00339971756120993	0.0518052199803418
GO:0030547	signaling receptor inhibitor activity	6/633	44/18639	0.136363636363636	4.01529513140887	0.00352574931502984	0.0528862397254476
GO:0070063	RNA polymerase binding	7/633	59/18639	0.11864406779661	3.493533617158	0.00371829469278965	0.0544363297427122
GO:0005528	FK506 binding	3/633	10/18639	0.3	8.83364928909953	0.00391261120025744	0.0544363297427122
GO:0008140	cAMP response element binding protein binding	3/633	10/18639	0.3	8.83364928909953	0.00391261120025744	0.0544363297427122
GO:0035256	G protein-coupled glutamate receptor binding	3/633	10/18639	0.3	8.83364928909953	0.00391261120025744	0.0544363297427122
GO:0098505	G-rich strand telomeric DNA binding	3/633	10/18639	0.3	8.83364928909953	0.00391261120025744	0.0544363297427122
GO:0071813	lipoprotein particle binding	5/633	32/18639	0.15625	4.60085900473934	0.00418653963113453	0.0566067330406923
GO:0071814	protein-lipid complex binding	5/633	32/18639	0.15625	4.60085900473934	0.00418653963113453	0.0566067330406923
GO:0019209	kinase activator activity	12/633	148/18639	0.0810810810810811	2.38747278083771	0.00465958128277956	0.0621277504370609
GO:0005525	GTP binding	23/633	378/18639	0.0608465608465608	1.79165726322124	0.00528555453229176	0.069508662342467
GO:0005507	copper ion binding	7/633	63/18639	0.111111111111111	3.27172195892575	0.00536947524611458	0.0696580572468918
GO:0050321	tau-protein kinase activity	4/633	22/18639	0.181818181818182	5.3537268418785	0.00591946354971004	0.0757691334362885
GO:0038024	cargo receptor activity	7/633	65/18639	0.107692307692308	3.1710535909588	0.00637627356359495	0.0805424029085678
GO:0044325	transmembrane transporter binding	11/633	136/18639	0.0808823529411765	2.38162113186507	0.0067163635162838	0.0816732669123902
GO:0005049	nuclear export signal receptor activity	3/633	12/18639	0.25	7.36137440758294	0.00681858262732188	0.0816732669123902
GO:0005527	macrolide binding	3/633	12/18639	0.25	7.36137440758294	0.00681858262732188	0.0816732669123902
GO:0043047	single-stranded telomeric DNA binding	3/633	12/18639	0.25	7.36137440758294	0.00681858262732188	0.0816732669123902
GO:0022853	active monoatomic ion transmembrane transporter activity	10/633	118/18639	0.0847457627118644	2.49538115511286	0.00693542129892774	0.0816732669123902
GO:0004602	glutathione peroxidase activity	4/633	23/18639	0.173913043478261	5.12095610962291	0.00697625821543333	0.0816732669123902
GO:0043021	ribonucleoprotein complex binding	13/633	177/18639	0.0734463276836158	2.16266366776448	0.00752887431946244	0.0870809559841439
GO:0023023	MHC protein complex binding	5/633	37/18639	0.135135135135135	3.97912130139618	0.00788720550966976	0.090139491539083
GO:0048027	mRNA 5'-UTR binding	4/633	24/18639	0.166666666666667	4.90758293838863	0.00815050888691051	0.0920528062521658
GO:0016853	isomerase activity	13/633	180/18639	0.0722222222222222	2.12661927330174	0.00861625483718293	0.0953701398159254
GO:0140666	annealing activity	3/633	13/18639	0.230769230769231	6.79511483776887	0.00864291892081824	0.0953701398159254
GO:0016860	intramolecular oxidoreductase activity	6/633	53/18639	0.113207547169811	3.33345256192435	0.00887571649269857	0.0968259981021662
GO:0097110	scaffold protein binding	7/633	70/18639	0.1	2.94454976303318	0.00950228784099203	0.102496587947779
GO:0003714	transcription corepressor activity	14/633	204/18639	0.0686274509803922	2.02076944521885	0.0100660601689513	0.105684946014075
GO:0019001	guanyl nucleotide binding	23/633	400/18639	0.0575	1.69311611374408	0.0101281406596822	0.105684946014075
GO:0032561	guanyl ribonucleotide binding	23/633	400/18639	0.0575	1.69311611374408	0.0101281406596822	0.105684946014075
GO:0003727	single-stranded RNA binding	8/633	89/18639	0.0898876404494382	2.64678630385005	0.0107222163436054	0.108389332639079
GO:0005161	platelet-derived growth factor receptor binding	3/633	14/18639	0.214285714285714	6.30974949221395	0.0107260277090755	0.108389332639079
GO:0032036	myosin heavy chain binding	3/633	14/18639	0.214285714285714	6.30974949221395	0.0107260277090755	0.108389332639079
GO:0042826	histone deacetylase binding	10/633	127/18639	0.078740157480315	2.31854312049856	0.0113769895918924	0.113769895918924
GO:0043539	protein serine/threonine kinase activator activity	7/633	73/18639	0.0958904109589041	2.82354086866195	0.0118455089070733	0.117233902585467
GO:0140776	protein-containing complex destabilizing activity	3/633	15/18639	0.2	5.88909952606635	0.013074115391517	0.127548357770874
GO:0019902	phosphatase binding	13/633	190/18639	0.068421052631579	2.01469194312796	0.0131534243951214	0.127548357770874
GO:0043175	RNA polymerase core enzyme binding	5/633	42/18639	0.119047619047619	3.5054163845633	0.0134056236447101	0.128693986989217
GO:0036002	pre-mRNA binding	6/633	59/18639	0.101694915254237	2.99445738613543	0.0147004515319791	0.139727064066336
GO:0003724	RNA helicase activity	7/633	77/18639	0.0909090909090909	2.67686342093925	0.01558365443923	0.143467866471762
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	3/633	16/18639	0.1875	5.5210308056872	0.015691797895349	0.143467866471762
GO:0030275	LRR domain binding	3/633	16/18639	0.1875	5.5210308056872	0.015691797895349	0.143467866471762
GO:0070411	I-SMAD binding	3/633	16/18639	0.1875	5.5210308056872	0.015691797895349	0.143467866471762
GO:0043014	alpha-tubulin binding	5/633	44/18639	0.113636363636364	3.34607927617406	0.0161971958996662	0.146691585506411
GO:0003735	structural constituent of ribosome	12/633	175/18639	0.0685714285714286	2.01911983750846	0.0165359327216234	0.148359770212696
GO:0008186	ATP-dependent activity, acting on RNA	7/633	79/18639	0.0886075949367089	2.60909472673826	0.0177368185297026	0.156214181546005
GO:0046332	SMAD binding	7/633	79/18639	0.0886075949367089	2.60909472673826	0.0177368185297026	0.156214181546005
GO:0016018	cyclosporin A binding	3/633	17/18639	0.176470588235294	5.1962642877056	0.0185822305426253	0.159276261793931
GO:0030169	low-density lipoprotein particle binding	3/633	17/18639	0.176470588235294	5.1962642877056	0.0185822305426253	0.159276261793931
GO:1990226	histone methyltransferase binding	3/633	17/18639	0.176470588235294	5.1962642877056	0.0185822305426253	0.159276261793931
GO:0001618	virus receptor activity	7/633	81/18639	0.0864197530864197	2.54467263472003	0.0200912161931703	0.170686438455252
GO:0030295	protein kinase activator activity	10/633	139/18639	0.0719424460431655	2.1183811244843	0.0202890069536775	0.17085479539939
GO:0140272	exogenous protein binding	7/633	82/18639	0.0853658536585366	2.51364004161369	0.0213465118823853	0.178196968757304
GO:0000900	mRNA regulatory element binding translation repressor activity	3/633	18/18639	0.166666666666667	4.90758293838863	0.0217472299742171	0.178438810044858
GO:1990381	ubiquitin-specific protease binding	3/633	18/18639	0.166666666666667	4.90758293838863	0.0217472299742171	0.178438810044858
GO:0140104	molecular carrier activity	15/633	249/18639	0.0602409638554217	1.77382515845372	0.0233848383462444	0.190249532308429
GO:0140416	transcription regulator inhibitor activity	4/633	33/18639	0.121212121212121	3.569151227919	0.0247096998074191	0.198352584445684
GO:0035254	glutamate receptor binding	5/633	49/18639	0.102040816326531	3.00464261533998	0.0247940730557104	0.198352584445684
GO:0016247	channel regulator activity	11/633	168/18639	0.0654761904761905	1.92797901150982	0.0285491849283225	0.226505930009832
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	3/633	20/18639	0.15	4.41682464454976	0.0289021816373777	0.227427003048218
GO:0061631	ubiquitin conjugating enzyme activity	4/633	35/18639	0.114285714285714	3.36519972918077	0.0299929131318521	0.234091029321772
GO:0141108	transporter regulator activity	11/633	170/18639	0.0647058823529412	1.90529690549205	0.0307641239173603	0.238173862586015
GO:0000993	RNA polymerase II complex binding	4/633	36/18639	0.111111111111111	3.27172195892575	0.0328653905100536	0.248617837866239
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	3/633	21/18639	0.142857142857143	4.20649966147596	0.0328900681343879	0.248617837866239
GO:0070182	DNA polymerase binding	3/633	21/18639	0.142857142857143	4.20649966147596	0.0328900681343879	0.248617837866239
GO:0003924	GTPase activity	18/633	331/18639	0.054380664652568	1.60126573216306	0.0343250106452935	0.257437579839702
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	7/633	91/18639	0.0769230769230769	2.26503827925629	0.0351575829906159	0.259625228238394
GO:0072341	modified amino acid binding	7/633	91/18639	0.0769230769230769	2.26503827925629	0.0351575829906159	0.259625228238394
GO:0003925	G protein activity	5/633	54/18639	0.0925925925925926	2.72643496577146	0.0358748163639476	0.262899417628929
GO:0043022	ribosome binding	8/633	112/18639	0.0714285714285714	2.10324983073798	0.0370323172309725	0.266139113894386
GO:0030021	extracellular matrix structural constituent conferring compression resistance	3/633	22/18639	0.136363636363636	4.01529513140887	0.037148584647758	0.266139113894386
GO:0140517	protein-RNA adaptor activity	3/633	22/18639	0.136363636363636	4.01529513140887	0.037148584647758	0.266139113894386
GO:0022804	active transmembrane transporter activity	23/633	457/18639	0.050328227571116	1.48193970568409	0.0398706437153347	0.283524577531269
GO:0019838	growth factor binding	9/633	136/18639	0.0661764705882353	1.9485991078896	0.0424691308601256	0.299782100189122
GO:0004090	carbonyl reductase (NADPH) activity	2/633	10/18639	0.2	5.88909952606635	0.0432511694882137	0.300877700787573
GO:0015924	mannosyl-oligosaccharide mannosidase activity	2/633	10/18639	0.2	5.88909952606635	0.0432511694882137	0.300877700787573
GO:0017022	myosin binding	6/633	76/18639	0.0789473684210526	2.32464454976303	0.0442998821147957	0.305956020361179
GO:0099106	ion channel regulator activity	10/633	160/18639	0.0625	1.84034360189573	0.0466328604112196	0.319768185676934
GO:0061650	ubiquitin-like protein conjugating enzyme activity	4/633	41/18639	0.0975609756097561	2.87273147612993	0.0495620939570898	0.335216786331405
GO:0001786	phosphatidylserine binding	5/633	59/18639	0.0847457627118644	2.49538115511286	0.0495841496448537	0.335216786331405
GO:0008017	microtubule binding	15/633	276/18639	0.0543478260869565	1.60029878425716	0.0503995816897545	0.335331673485799
GO:0015078	proton transmembrane transporter activity	11/633	185/18639	0.0594594594594595	1.75081337261432	0.0513865491630549	0.335331673485799
GO:0008199	ferric iron binding	2/633	11/18639	0.181818181818182	5.3537268418785	0.0516969663290607	0.335331673485799
GO:0010854	adenylate cyclase regulator activity	2/633	11/18639	0.181818181818182	5.3537268418785	0.0516969663290607	0.335331673485799
GO:0032050	clathrin heavy chain binding	2/633	11/18639	0.181818181818182	5.3537268418785	0.0516969663290607	0.335331673485799
GO:0043522	leucine zipper domain binding	2/633	11/18639	0.181818181818182	5.3537268418785	0.0516969663290607	0.335331673485799
GO:0035198	miRNA binding	4/633	42/18639	0.0952380952380952	2.80433310765064	0.0533680382004983	0.343847762902539
GO:0008198	ferrous iron binding	3/633	26/18639	0.115384615384615	3.39755741888443	0.0568121804200715	0.358813771074136
GO:0050681	nuclear androgen receptor binding	3/633	26/18639	0.115384615384615	3.39755741888443	0.0568121804200715	0.358813771074136
GO:0070006	metalloaminopeptidase activity	3/633	26/18639	0.115384615384615	3.39755741888443	0.0568121804200715	0.358813771074136
GO:0019903	protein phosphatase binding	9/633	144/18639	0.0625	1.84034360189573	0.057187110284768	0.358821084139721
GO:0004859	phospholipase inhibitor activity	2/633	12/18639	0.166666666666667	4.90758293838863	0.0606726430694085	0.364035858416451
GO:0008179	adenylate cyclase binding	2/633	12/18639	0.166666666666667	4.90758293838863	0.0606726430694085	0.364035858416451
GO:0010853	cyclase activator activity	2/633	12/18639	0.166666666666667	4.90758293838863	0.0606726430694085	0.364035858416451
GO:0035259	nuclear glucocorticoid receptor binding	2/633	12/18639	0.166666666666667	4.90758293838863	0.0606726430694085	0.364035858416451
GO:0035497	cAMP response element binding	2/633	12/18639	0.166666666666667	4.90758293838863	0.0606726430694085	0.364035858416451
GO:0070008	serine-type exopeptidase activity	2/633	12/18639	0.166666666666667	4.90758293838863	0.0606726430694085	0.364035858416451
GO:1990459	transferrin receptor binding	2/633	12/18639	0.166666666666667	4.90758293838863	0.0606726430694085	0.364035858416451
GO:0001046	core promoter sequence-specific DNA binding	4/633	44/18639	0.0909090909090909	2.67686342093925	0.0614412103643245	0.366357527638208
GO:0042605	peptide antigen binding	4/633	45/18639	0.0888888888888889	2.6173775671406	0.0657059495815127	0.389368590112668
GO:0004519	endonuclease activity	8/633	127/18639	0.062992125984252	1.85483449639885	0.0678987722999437	0.398386326615518
GO:0019789	SUMO transferase activity	3/633	28/18639	0.107142857142857	3.15487474610697	0.0681498011487793	0.398386326615518
GO:0019843	rRNA binding	5/633	65/18639	0.0769230769230769	2.26503827925629	0.0695840677844405	0.398386326615518
GO:0005542	folic acid binding	2/633	13/18639	0.153846153846154	4.53007655851258	0.0701325929146068	0.398386326615518
GO:0008035	high-density lipoprotein particle binding	2/633	13/18639	0.153846153846154	4.53007655851258	0.0701325929146068	0.398386326615518
GO:0031432	titin binding	2/633	13/18639	0.153846153846154	4.53007655851258	0.0701325929146068	0.398386326615518
GO:0039706	co-receptor binding	2/633	13/18639	0.153846153846154	4.53007655851258	0.0701325929146068	0.398386326615518
GO:0000510	H3-H4 histone complex chaperone activity	9/633	151/18639	0.0596026490066225	1.755029660086	0.0724800372868548	0.402201362979079
GO:0140584	chromatin extrusion motor activity	9/633	151/18639	0.0596026490066225	1.755029660086	0.0724800372868548	0.402201362979079
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	9/633	151/18639	0.0596026490066225	1.755029660086	0.0724800372868548	0.402201362979079
GO:0140849	ATP-dependent H2AZ histone chaperone activity	9/633	151/18639	0.0596026490066225	1.755029660086	0.0724800372868548	0.402201362979079
GO:0106222	lncRNA binding	3/633	29/18639	0.103448275862069	3.04608596175846	0.0741734123150999	0.405980791220701
GO:0140359	ABC-type transporter activity	4/633	47/18639	0.0851063829787234	2.50599979832611	0.0746837672030693	0.405980791220701
GO:0015616	DNA translocase activity	9/633	152/18639	0.0592105263157895	1.74348341232227	0.0748527083813168	0.405980791220701
GO:0140674	ATP-dependent histone chaperone activity	9/633	152/18639	0.0592105263157895	1.74348341232227	0.0748527083813168	0.405980791220701
GO:0016798	hydrolase activity, acting on glycosyl bonds	8/633	130/18639	0.0615384615384615	1.81203062340503	0.0755353620715179	0.407306500838053
GO:0004857	enzyme inhibitor activity	20/633	416/18639	0.0480769230769231	1.41564892453518	0.0759456913020953	0.407306500838053
GO:0061775	cohesin loader activity	9/633	153/18639	0.0588235294117647	1.73208809590187	0.0772726594924495	0.409390768421707
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	4/633	48/18639	0.0833333333333333	2.45379146919431	0.079393009021643	0.409390768421707
GO:0038187	pattern recognition receptor activity	4/633	48/18639	0.0833333333333333	2.45379146919431	0.079393009021643	0.409390768421707
GO:0005096	GTPase activator activity	14/633	271/18639	0.0516605166051661	1.52116961927913	0.0794534982464687	0.409390768421707
GO:0034236	protein kinase A catalytic subunit binding	2/633	14/18639	0.142857142857143	4.20649966147596	0.0800336871155287	0.409390768421707
GO:0043176	amine binding	2/633	14/18639	0.142857142857143	4.20649966147596	0.0800336871155287	0.409390768421707
GO:1990825	sequence-specific mRNA binding	2/633	14/18639	0.142857142857143	4.20649966147596	0.0800336871155287	0.409390768421707
GO:0016769	transferase activity, transferring nitrogenous groups	3/633	30/18639	0.1	2.94454976303318	0.0804241961118297	0.409390768421707
GO:0048019	receptor antagonist activity	3/633	30/18639	0.1	2.94454976303318	0.0804241961118297	0.409390768421707
GO:0003712	transcription coregulator activity	23/633	495/18639	0.0464646464646465	1.36817463736895	0.0808415517846667	0.409390768421707
GO:1990841	promoter-specific chromatin binding	5/633	68/18639	0.0735294117647059	2.16511011987733	0.0810252562501294	0.409390768421707
GO:0004386	helicase activity	9/633	155/18639	0.0580645161290323	1.70973857208378	0.0822545462642671	0.413425991694745
GO:0001664	G protein-coupled receptor binding	15/633	297/18639	0.0505050505050505	1.48714634496625	0.0827215606370355	0.413607803185178
GO:0005200	structural constituent of cytoskeleton	7/633	112/18639	0.0625	1.84034360189573	0.087043491121977	0.432962442886518
GO:0140658	ATP-dependent chromatin remodeler activity	9/633	158/18639	0.0569620253164557	1.67727518147459	0.0900823056101511	0.437988653034926
GO:0004559	alpha-mannosidase activity	2/633	15/18639	0.133333333333333	3.9260663507109	0.0903351596884534	0.437988653034926
GO:0005041	low-density lipoprotein particle receptor activity	2/633	15/18639	0.133333333333333	3.9260663507109	0.0903351596884534	0.437988653034926
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	2/633	15/18639	0.133333333333333	3.9260663507109	0.0903351596884534	0.437988653034926
GO:0055105	ubiquitin-protein transferase inhibitor activity	2/633	15/18639	0.133333333333333	3.9260663507109	0.0903351596884534	0.437988653034926
GO:0002020	protease binding	8/633	136/18639	0.0588235294117647	1.73208809590187	0.0922970127869577	0.444723958071236
GO:0031369	translation initiation factor binding	3/633	32/18639	0.09375	2.7605154028436	0.093577332844156	0.444723958071236
GO:0051059	NF-kappaB binding	3/633	32/18639	0.09375	2.7605154028436	0.093577332844156	0.444723958071236
GO:0140142	nucleocytoplasmic carrier activity	3/633	32/18639	0.09375	2.7605154028436	0.093577332844156	0.444723958071236
GO:0003689	DNA clamp loader activity	9/633	160/18639	0.05625	1.65630924170616	0.0955368971980097	0.451800104975809
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	2/633	16/18639	0.125	3.68068720379147	0.100998497087468	0.465840709020778
GO:0005324	long-chain fatty acid transmembrane transporter activity	2/633	16/18639	0.125	3.68068720379147	0.100998497087468	0.465840709020778
GO:0015923	mannosidase activity	2/633	16/18639	0.125	3.68068720379147	0.100998497087468	0.465840709020778
GO:0022858	alanine transmembrane transporter activity	2/633	16/18639	0.125	3.68068720379147	0.100998497087468	0.465840709020778
GO:0055102	lipase inhibitor activity	2/633	16/18639	0.125	3.68068720379147	0.100998497087468	0.465840709020778
GO:0070851	growth factor receptor binding	8/633	139/18639	0.0575539568345324	1.69470489958744	0.101417404359732	0.465840709020778
GO:0140296	general transcription initiation factor binding	4/633	53/18639	0.0754716981132075	2.22230170794957	0.105048605364562	0.480222195952284
GO:0140713	histone chaperone activity	9/633	164/18639	0.0548780487804878	1.61591145532308	0.107008894055819	0.486865110396143
GO:0090482	vitamin transmembrane transporter activity	3/633	34/18639	0.0882352941176471	2.5981321438528	0.107546936379468	0.487004994925892
GO:0140597	protein carrier chaperone	10/633	188/18639	0.0531914893617021	1.56624987395382	0.108132373862503	0.487357177971845
GO:0050661	NADP binding	4/633	54/18639	0.0740740740740741	2.18114797261717	0.110582508484611	0.49607106609919
GO:0003730	mRNA 3'-UTR binding	13/633	262/18639	0.049618320610687	1.46103614196303	0.111591884488117	0.497721478341249
GO:0070402	NADPH binding	2/633	17/18639	0.117647058823529	3.46417619180374	0.111987332626781	0.497721478341249
GO:0140313	molecular sequestering activity	4/633	55/18639	0.0727272727272727	2.1414907367514	0.116243625956402	0.514257515751823
GO:0015172	acidic amino acid transmembrane transporter activity	2/633	18/18639	0.111111111111111	3.27172195892575	0.123267345458351	0.535459962172024
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	2/633	18/18639	0.111111111111111	3.27172195892575	0.123267345458351	0.535459962172024
GO:0030228	lipoprotein particle receptor activity	2/633	18/18639	0.111111111111111	3.27172195892575	0.123267345458351	0.535459962172024
GO:0050811	GABA receptor binding	2/633	18/18639	0.111111111111111	3.27172195892575	0.123267345458351	0.535459962172024
GO:0043130	ubiquitin binding	6/633	100/18639	0.06	1.76672985781991	0.124887021648711	0.540051985507941
GO:0043394	proteoglycan binding	3/633	37/18639	0.0810810810810811	2.38747278083771	0.129889133407648	0.559163982382701
GO:0061980	regulatory RNA binding	4/633	58/18639	0.0689655172413793	2.03072397450564	0.133956997118962	0.570105362824864
GO:0008574	plus-end-directed microtubule motor activity	2/633	19/18639	0.105263157894737	3.09952606635071	0.134806163917963	0.570105362824864
GO:0015245	fatty acid transmembrane transporter activity	2/633	19/18639	0.105263157894737	3.09952606635071	0.134806163917963	0.570105362824864
GO:0050145	nucleoside monophosphate kinase activity	2/633	19/18639	0.105263157894737	3.09952606635071	0.134806163917963	0.570105362824864
GO:0048306	calcium-dependent protein binding	5/633	80/18639	0.0625	1.84034360189573	0.1358271476703	0.571127042277073
GO:0015459	potassium channel regulator activity	4/633	59/18639	0.0677966101694915	1.99630492409029	0.140093204207988	0.571127042277073
GO:0033192	calmodulin-dependent protein phosphatase activity	5/633	81/18639	0.0617283950617284	1.81762331051431	0.140996988562152	0.571127042277073
GO:0140791	histone H2AXS140 phosphatase activity	5/633	81/18639	0.0617283950617284	1.81762331051431	0.140996988562152	0.571127042277073
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	5/633	81/18639	0.0617283950617284	1.81762331051431	0.140996988562152	0.571127042277073
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	5/633	81/18639	0.0617283950617284	1.81762331051431	0.140996988562152	0.571127042277073
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	5/633	81/18639	0.0617283950617284	1.81762331051431	0.140996988562152	0.571127042277073
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	5/633	81/18639	0.0617283950617284	1.81762331051431	0.140996988562152	0.571127042277073
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	5/633	81/18639	0.0617283950617284	1.81762331051431	0.140996988562152	0.571127042277073
GO:1990439	MAP kinase serine/threonine phosphatase activity	5/633	81/18639	0.0617283950617284	1.81762331051431	0.140996988562152	0.571127042277073
GO:0016776	phosphotransferase activity, phosphate group as acceptor	3/633	39/18639	0.0769230769230769	2.26503827925629	0.145611182178235	0.579054905917036
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	5/633	82/18639	0.0609756097560976	1.7954571725812	0.146251357821088	0.579054905917036
GO:0033549	MAP kinase phosphatase activity	5/633	82/18639	0.0609756097560976	1.7954571725812	0.146251357821088	0.579054905917036
GO:0001098	basal transcription machinery binding	4/633	60/18639	0.0666666666666667	1.96303317535545	0.146339275399987	0.579054905917036
GO:0001099	basal RNA polymerase II transcription machinery binding	4/633	60/18639	0.0666666666666667	1.96303317535545	0.146339275399987	0.579054905917036
GO:0010851	cyclase regulator activity	2/633	20/18639	0.1	2.94454976303318	0.14657327306025	0.579054905917036
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	5/633	83/18639	0.0602409638554217	1.77382515845372	0.15158824644309	0.594948263667931
GO:0005319	lipid transporter activity	9/633	178/18639	0.050561797752809	1.48881729591565	0.152880992546363	0.594948263667931
GO:0004177	aminopeptidase activity	3/633	40/18639	0.075	2.20841232227488	0.153694968114216	0.594948263667931
GO:0061791	GTPase motor activity	3/633	40/18639	0.075	2.20841232227488	0.153694968114216	0.594948263667931
GO:1990606	membrane scission GTPase motor activity	3/633	40/18639	0.075	2.20841232227488	0.153694968114216	0.594948263667931
GO:0004860	protein kinase inhibitor activity	5/633	84/18639	0.0595238095238095	1.75270819228165	0.157005593014172	0.60049947925739
GO:0017018	myosin phosphatase activity	5/633	84/18639	0.0595238095238095	1.75270819228165	0.157005593014172	0.60049947925739
GO:0051117	ATPase binding	5/633	84/18639	0.0595238095238095	1.75270819228165	0.157005593014172	0.60049947925739
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	2/633	21/18639	0.0952380952380952	2.80433310765064	0.15853992621034	0.603874464992871
GO:0015179	L-amino acid transmembrane transporter activity	4/633	62/18639	0.0645161290322581	1.89970952453753	0.159146082961663	0.603874464992871
GO:0015175	neutral L-amino acid transmembrane transporter activity	3/633	41/18639	0.0731707317073171	2.15454860709745	0.161915984495041	0.611387678925129
GO:0004520	DNA endonuclease activity	3/633	42/18639	0.0714285714285714	2.10324983073798	0.170265826517699	0.611387678925129
GO:0032931	histone H3K56 acetyltransferase activity	2/633	22/18639	0.0909090909090909	2.67686342093925	0.170679060366599	0.611387678925129
GO:0043992	histone H3K9 acetyltransferase activity	2/633	22/18639	0.0909090909090909	2.67686342093925	0.170679060366599	0.611387678925129
GO:0043993	histone H3K18 acetyltransferase activity	2/633	22/18639	0.0909090909090909	2.67686342093925	0.170679060366599	0.611387678925129
GO:0043994	histone H3K23 acetyltransferase activity	2/633	22/18639	0.0909090909090909	2.67686342093925	0.170679060366599	0.611387678925129
GO:0043999	histone H2AK5 acetyltransferase activity	2/633	22/18639	0.0909090909090909	2.67686342093925	0.170679060366599	0.611387678925129
GO:0044012	histone H2AK9 acetyltransferase activity	2/633	22/18639	0.0909090909090909	2.67686342093925	0.170679060366599	0.611387678925129
GO:0044014	histone H2BK5 acetyltransferase activity	2/633	22/18639	0.0909090909090909	2.67686342093925	0.170679060366599	0.611387678925129
GO:0044015	histone H2BK12 acetyltransferase activity	2/633	22/18639	0.0909090909090909	2.67686342093925	0.170679060366599	0.611387678925129
GO:0044016	histone H3K4 acetyltransferase activity	2/633	22/18639	0.0909090909090909	2.67686342093925	0.170679060366599	0.611387678925129
GO:0044017	histone H3K27 acetyltransferase activity	2/633	22/18639	0.0909090909090909	2.67686342093925	0.170679060366599	0.611387678925129
GO:0044018	histone H3K36 acetyltransferase activity	2/633	22/18639	0.0909090909090909	2.67686342093925	0.170679060366599	0.611387678925129
GO:0046972	histone H4K16 acetyltransferase activity	2/633	22/18639	0.0909090909090909	2.67686342093925	0.170679060366599	0.611387678925129
GO:0140908	histone H3K122 acetyltransferase activity	2/633	22/18639	0.0909090909090909	2.67686342093925	0.170679060366599	0.611387678925129
GO:0004518	nuclease activity	10/633	209/18639	0.0478468899521531	1.40887548470487	0.174966286940466	0.624415001720622
GO:0008094	ATP-dependent activity, acting on DNA	10/633	210/18639	0.0476190476190476	1.40216655382532	0.178554788918387	0.63316128583087
GO:0008375	acetylglucosaminyltransferase activity	3/633	43/18639	0.0697674418604651	2.05433704397663	0.178736154646006	0.63316128583087
GO:0005178	integrin binding	8/633	161/18639	0.0496894409937888	1.46313031703512	0.182438427017138	0.638714933395376
GO:0031681	G-protein beta-subunit binding	2/633	23/18639	0.0869565217391304	2.56047805481146	0.18296521529555	0.638714933395376
GO:0044013	histone H2B acetyltransferase activity	2/633	23/18639	0.0869565217391304	2.56047805481146	0.18296521529555	0.638714933395376
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	2/633	23/18639	0.0869565217391304	2.56047805481146	0.18296521529555	0.638714933395376
GO:0031406	carboxylic acid binding	9/633	187/18639	0.0481283422459893	1.41716298755607	0.186727863868664	0.649488222151874
GO:0019210	kinase inhibitor activity	5/633	90/18639	0.0555555555555556	1.63586097946288	0.191078183205806	0.653351124663922
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	4/633	67/18639	0.0597014925373134	1.75794015703473	0.192819167416317	0.653351124663922
GO:0043177	organic acid binding	9/633	189/18639	0.0476190476190476	1.40216655382532	0.194667368865328	0.653351124663922
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	2/633	24/18639	0.0833333333333333	2.45379146919431	0.195374456166393	0.653351124663922
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	2/633	24/18639	0.0833333333333333	2.45379146919431	0.195374456166393	0.653351124663922
GO:0004622	lysophospholipase activity	2/633	24/18639	0.0833333333333333	2.45379146919431	0.195374456166393	0.653351124663922
GO:0015295	solute:proton symporter activity	2/633	24/18639	0.0833333333333333	2.45379146919431	0.195374456166393	0.653351124663922
GO:0043998	histone H2A acetyltransferase activity	2/633	24/18639	0.0833333333333333	2.45379146919431	0.195374456166393	0.653351124663922
GO:0050431	transforming growth factor beta binding	2/633	24/18639	0.0833333333333333	2.45379146919431	0.195374456166393	0.653351124663922
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/633	24/18639	0.0833333333333333	2.45379146919431	0.195374456166393	0.653351124663922
GO:0004715	non-membrane spanning protein tyrosine kinase activity	3/633	45/18639	0.0666666666666667	1.96303317535545	0.196005337399177	0.653351124663922
GO:0046915	transition metal ion transmembrane transporter activity	3/633	45/18639	0.0666666666666667	1.96303317535545	0.196005337399177	0.653351124663922
GO:0015294	solute:monoatomic cation symporter activity	6/633	116/18639	0.0517241379310345	1.52304298087923	0.202095307022565	0.663019693008089
GO:0004180	carboxypeptidase activity	3/633	46/18639	0.0652173913043478	1.92035854110859	0.204787983724535	0.663019693008089
GO:0030276	clathrin binding	3/633	46/18639	0.0652173913043478	1.92035854110859	0.204787983724535	0.663019693008089
GO:0001848	complement binding	2/633	25/18639	0.08	2.35563981042654	0.207884299578578	0.663019693008089
GO:0003707	nuclear steroid receptor activity	2/633	25/18639	0.08	2.35563981042654	0.207884299578578	0.663019693008089
GO:0005537	D-mannose binding	2/633	25/18639	0.08	2.35563981042654	0.207884299578578	0.663019693008089
GO:0015662	P-type ion transporter activity	2/633	25/18639	0.08	2.35563981042654	0.207884299578578	0.663019693008089
GO:0017025	TBP-class protein binding	2/633	25/18639	0.08	2.35563981042654	0.207884299578578	0.663019693008089
GO:0019706	protein-cysteine S-palmitoyltransferase activity	2/633	25/18639	0.08	2.35563981042654	0.207884299578578	0.663019693008089
GO:0019707	protein-cysteine S-acyltransferase activity	2/633	25/18639	0.08	2.35563981042654	0.207884299578578	0.663019693008089
GO:0047617	fatty acyl-CoA hydrolase activity	2/633	25/18639	0.08	2.35563981042654	0.207884299578578	0.663019693008089
GO:0120020	cholesterol transfer activity	2/633	25/18639	0.08	2.35563981042654	0.207884299578578	0.663019693008089
GO:0140358	P-type transmembrane transporter activity	2/633	25/18639	0.08	2.35563981042654	0.207884299578578	0.663019693008089
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	20/633	484/18639	0.0413223140495868	1.21675610042693	0.213547769172074	0.678827345712553
GO:0140857	histone H3T45 kinase activity	11/633	246/18639	0.0447154471544715	1.31666859322622	0.216480617701928	0.682757087510049
GO:0035403	histone H3T6 kinase activity	11/633	247/18639	0.0445344129554656	1.31133795114838	0.220195487222036	0.682757087510049
GO:0004112	cyclic-nucleotide phosphodiesterase activity	2/633	26/18639	0.0769230769230769	2.26503827925629	0.220473642841787	0.682757087510049
GO:0005160	transforming growth factor beta receptor binding	2/633	26/18639	0.0769230769230769	2.26503827925629	0.220473642841787	0.682757087510049
GO:0008143	poly(A) binding	2/633	26/18639	0.0769230769230769	2.26503827925629	0.220473642841787	0.682757087510049
GO:0016289	acyl-CoA hydrolase activity	2/633	26/18639	0.0769230769230769	2.26503827925629	0.220473642841787	0.682757087510049
GO:0043548	phosphatidylinositol 3-kinase binding	2/633	26/18639	0.0769230769230769	2.26503827925629	0.220473642841787	0.682757087510049
GO:0070412	R-SMAD binding	2/633	26/18639	0.0769230769230769	2.26503827925629	0.220473642841787	0.682757087510049
GO:0016879	ligase activity, forming carbon-nitrogen bonds	3/633	48/18639	0.0625	1.84034360189573	0.222609773542652	0.684953149362007
GO:0032266	phosphatidylinositol-3-phosphate binding	3/633	48/18639	0.0625	1.84034360189573	0.222609773542652	0.684953149362007
GO:0032182	ubiquitin-like protein binding	6/633	120/18639	0.05	1.47227488151659	0.223671533372398	0.686021316413745
GO:0030695	GTPase regulator activity	20/633	489/18639	0.0408997955010225	1.20431483150641	0.226725041884231	0.693172102575992
GO:0005518	collagen binding	4/633	72/18639	0.0555555555555556	1.63586097946288	0.228464040729184	0.696271362222275
GO:0060589	nucleoside-triphosphatase regulator activity	20/633	490/18639	0.0408163265306122	1.20185704613599	0.229403341729806	0.696921544495614
GO:0001216	DNA-binding transcription activator activity	20/633	491/18639	0.0407331975560081	1.19940927211127	0.23209557201477	0.697189372331256
GO:0004364	glutathione transferase activity	2/633	27/18639	0.0740740740740741	2.18114797261717	0.233122696373264	0.697189372331256
GO:0005044	scavenger receptor activity	2/633	27/18639	0.0740740740740741	2.18114797261717	0.233122696373264	0.697189372331256
GO:0005385	zinc ion transmembrane transporter activity	2/633	27/18639	0.0740740740740741	2.18114797261717	0.233122696373264	0.697189372331256
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	2/633	27/18639	0.0740740740740741	2.18114797261717	0.233122696373264	0.697189372331256
GO:0140996	histone H3 kinase activity	15/633	357/18639	0.0420168067226891	1.23720578278705	0.2345667619331	0.699329476570733
GO:0003678	DNA helicase activity	4/633	74/18639	0.0540540540540541	1.59164852055847	0.243162971979999	0.700649387476097
GO:0048029	monosaccharide binding	4/633	74/18639	0.0540540540540541	1.59164852055847	0.243162971979999	0.700649387476097
GO:0035173	histone kinase activity	15/633	360/18639	0.0416666666666667	1.22689573459716	0.244214815013085	0.700649387476097
GO:0036408	histone H3K14 acetyltransferase activity	2/633	28/18639	0.0714285714285714	2.10324983073798	0.245812919082839	0.700649387476097
GO:0046966	nuclear thyroid hormone receptor binding	2/633	28/18639	0.0714285714285714	2.10324983073798	0.245812919082839	0.700649387476097
GO:0051019	mitogen-activated protein kinase binding	2/633	28/18639	0.0714285714285714	2.10324983073798	0.245812919082839	0.700649387476097
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	2/633	28/18639	0.0714285714285714	2.10324983073798	0.245812919082839	0.700649387476097
GO:0005272	sodium channel activity	3/633	51/18639	0.0588235294117647	1.73208809590187	0.249869072321109	0.700649387476097
GO:0016830	carbon-carbon lyase activity	3/633	51/18639	0.0588235294117647	1.73208809590187	0.249869072321109	0.700649387476097
GO:0140097	catalytic activity, acting on DNA	14/633	336/18639	0.0416666666666667	1.22689573459716	0.253865422180157	0.700649387476097
GO:0010484	histone H3 acetyltransferase activity	2/633	29/18639	0.0689655172413793	2.03072397450564	0.258526956621191	0.700649387476097
GO:0016417	S-acyltransferase activity	2/633	29/18639	0.0689655172413793	2.03072397450564	0.258526956621191	0.700649387476097
GO:0099604	ligand-gated calcium channel activity	2/633	29/18639	0.0689655172413793	2.03072397450564	0.258526956621191	0.700649387476097
GO:0005080	protein kinase C binding	3/633	52/18639	0.0576923076923077	1.69877870944222	0.25906646009537	0.700649387476097
GO:0003774	cytoskeletal motor activity	7/633	153/18639	0.0457516339869281	1.3471796301459	0.264338948043331	0.700649387476097
GO:0008238	exopeptidase activity	5/633	102/18639	0.0490196078431373	1.44340674658489	0.26570721563468	0.700649387476097
GO:0015171	amino acid transmembrane transporter activity	5/633	102/18639	0.0490196078431373	1.44340674658489	0.26570721563468	0.700649387476097
GO:0004864	protein phosphatase inhibitor activity	3/633	53/18639	0.0566037735849057	1.66672628096217	0.268307531379218	0.700649387476097
GO:0005246	calcium channel regulator activity	3/633	53/18639	0.0566037735849057	1.66672628096217	0.268307531379218	0.700649387476097
GO:0008106	alcohol dehydrogenase (NADP+) activity	2/633	30/18639	0.0666666666666667	1.96303317535545	0.27124858237186	0.700649387476097
GO:0033612	receptor serine/threonine kinase binding	2/633	30/18639	0.0666666666666667	1.96303317535545	0.27124858237186	0.700649387476097
GO:0035925	mRNA 3'-UTR AU-rich region binding	2/633	30/18639	0.0666666666666667	1.96303317535545	0.27124858237186	0.700649387476097
GO:0043995	histone H4K5 acetyltransferase activity	2/633	30/18639	0.0666666666666667	1.96303317535545	0.27124858237186	0.700649387476097
GO:0043996	histone H4K8 acetyltransferase activity	2/633	30/18639	0.0666666666666667	1.96303317535545	0.27124858237186	0.700649387476097
GO:0043997	histone H4K12 acetyltransferase activity	2/633	30/18639	0.0666666666666667	1.96303317535545	0.27124858237186	0.700649387476097
GO:0070566	adenylyltransferase activity	2/633	30/18639	0.0666666666666667	1.96303317535545	0.27124858237186	0.700649387476097
GO:0004722	protein serine/threonine phosphatase activity	5/633	103/18639	0.0485436893203883	1.42939308885106	0.272217840062914	0.700649387476097
GO:0019787	ubiquitin-like protein transferase activity	19/633	479/18639	0.0396659707724426	1.16798424838477	0.275598143319796	0.700649387476097
GO:0051015	actin filament binding	9/633	209/18639	0.0430622009569378	1.26798793623438	0.280953612987081	0.700649387476097
GO:0008327	methyl-CpG binding	2/633	31/18639	0.0645161290322581	1.89970952453753	0.283962641072351	0.700649387476097
GO:0017147	Wnt-protein binding	2/633	31/18639	0.0645161290322581	1.89970952453753	0.283962641072351	0.700649387476097
GO:0047499	calcium-independent phospholipase A2 activity	2/633	31/18639	0.0645161290322581	1.89970952453753	0.283962641072351	0.700649387476097
GO:0070273	phosphatidylinositol-4-phosphate binding	2/633	31/18639	0.0645161290322581	1.89970952453753	0.283962641072351	0.700649387476097
GO:0072349	modified amino acid transmembrane transporter activity	2/633	31/18639	0.0645161290322581	1.89970952453753	0.283962641072351	0.700649387476097
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	1/633	10/18639	0.1	2.94454976303318	0.29220172225426	0.700649387476097
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/633	10/18639	0.1	2.94454976303318	0.29220172225426	0.700649387476097
GO:0005031	tumor necrosis factor receptor activity	1/633	10/18639	0.1	2.94454976303318	0.29220172225426	0.700649387476097
GO:0005381	iron ion transmembrane transporter activity	1/633	10/18639	0.1	2.94454976303318	0.29220172225426	0.700649387476097
GO:0008190	eukaryotic initiation factor 4E binding	1/633	10/18639	0.1	2.94454976303318	0.29220172225426	0.700649387476097
GO:0008239	dipeptidyl-peptidase activity	1/633	10/18639	0.1	2.94454976303318	0.29220172225426	0.700649387476097
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	1/633	10/18639	0.1	2.94454976303318	0.29220172225426	0.700649387476097
GO:0008519	ammonium channel activity	1/633	10/18639	0.1	2.94454976303318	0.29220172225426	0.700649387476097
GO:0008641	ubiquitin-like modifier activating enzyme activity	1/633	10/18639	0.1	2.94454976303318	0.29220172225426	0.700649387476097
GO:0015203	polyamine transmembrane transporter activity	1/633	10/18639	0.1	2.94454976303318	0.29220172225426	0.700649387476097
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/633	10/18639	0.1	2.94454976303318	0.29220172225426	0.700649387476097
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	1/633	10/18639	0.1	2.94454976303318	0.29220172225426	0.700649387476097
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	1/633	10/18639	0.1	2.94454976303318	0.29220172225426	0.700649387476097
GO:0030957	Tat protein binding	1/633	10/18639	0.1	2.94454976303318	0.29220172225426	0.700649387476097
GO:0031996	thioesterase binding	1/633	10/18639	0.1	2.94454976303318	0.29220172225426	0.700649387476097
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	1/633	10/18639	0.1	2.94454976303318	0.29220172225426	0.700649387476097
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/633	10/18639	0.1	2.94454976303318	0.29220172225426	0.700649387476097
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/633	10/18639	0.1	2.94454976303318	0.29220172225426	0.700649387476097
GO:0051378	serotonin binding	1/633	10/18639	0.1	2.94454976303318	0.29220172225426	0.700649387476097
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/633	10/18639	0.1	2.94454976303318	0.29220172225426	0.700649387476097
GO:1905394	retromer complex binding	1/633	10/18639	0.1	2.94454976303318	0.29220172225426	0.700649387476097
GO:0015101	organic cation transmembrane transporter activity	4/633	81/18639	0.0493827160493827	1.45409864841144	0.296021765521324	0.700649387476097
GO:0019212	phosphatase inhibitor activity	3/633	56/18639	0.0535714285714286	1.57743737305349	0.296225637062826	0.700649387476097
GO:0170055	lipid transmembrane transporter activity	3/633	56/18639	0.0535714285714286	1.57743737305349	0.296225637062826	0.700649387476097
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2/633	32/18639	0.0625	1.84034360189573	0.296654994954231	0.700649387476097
GO:0042910	xenobiotic transmembrane transporter activity	2/633	32/18639	0.0625	1.84034360189573	0.296654994954231	0.700649387476097
GO:0047498	calcium-dependent phospholipase A2 activity	2/633	32/18639	0.0625	1.84034360189573	0.296654994954231	0.700649387476097
GO:0070717	poly-purine tract binding	2/633	32/18639	0.0625	1.84034360189573	0.296654994954231	0.700649387476097
GO:0120015	sterol transfer activity	2/633	32/18639	0.0625	1.84034360189573	0.296654994954231	0.700649387476097
GO:0004674	protein serine/threonine kinase activity	17/633	433/18639	0.0392609699769053	1.15605879841949	0.304240114784801	0.700649387476097
GO:0004843	cysteine-type deubiquitinase activity	5/633	108/18639	0.0462962962962963	1.36321748288573	0.305226752998905	0.700649387476097
GO:0016504	peptidase activator activity	3/633	57/18639	0.0526315789473684	1.54976303317536	0.3055751557305	0.700649387476097
GO:0046943	carboxylic acid transmembrane transporter activity	8/633	188/18639	0.0425531914893617	1.25299989916305	0.30840513362937	0.700649387476097
GO:0140311	protein sequestering activity	2/633	33/18639	0.0606060606060606	1.7845756139595	0.309312472296579	0.700649387476097
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	10/633	243/18639	0.0411522633744856	1.2117488736762	0.312821040541447	0.700649387476097
GO:0005342	organic acid transmembrane transporter activity	8/633	189/18639	0.0423280423280423	1.24637027006695	0.313432217154853	0.700649387476097
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	1/633	11/18639	0.0909090909090909	2.67686342093925	0.31625219784678	0.700649387476097
GO:0005114	type II transforming growth factor beta receptor binding	1/633	11/18639	0.0909090909090909	2.67686342093925	0.31625219784678	0.700649387476097
GO:0008046	axon guidance receptor activity	1/633	11/18639	0.0909090909090909	2.67686342093925	0.31625219784678	0.700649387476097
GO:0008526	phosphatidylinositol transfer activity	1/633	11/18639	0.0909090909090909	2.67686342093925	0.31625219784678	0.700649387476097
GO:0015173	aromatic amino acid transmembrane transporter activity	1/633	11/18639	0.0909090909090909	2.67686342093925	0.31625219784678	0.700649387476097
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/633	11/18639	0.0909090909090909	2.67686342093925	0.31625219784678	0.700649387476097
GO:0019107	myristoyltransferase activity	1/633	11/18639	0.0909090909090909	2.67686342093925	0.31625219784678	0.700649387476097
GO:0019206	nucleoside kinase activity	1/633	11/18639	0.0909090909090909	2.67686342093925	0.31625219784678	0.700649387476097
GO:0034056	estrogen response element binding	1/633	11/18639	0.0909090909090909	2.67686342093925	0.31625219784678	0.700649387476097
GO:0034713	type I transforming growth factor beta receptor binding	1/633	11/18639	0.0909090909090909	2.67686342093925	0.31625219784678	0.700649387476097
GO:0042608	T cell receptor binding	1/633	11/18639	0.0909090909090909	2.67686342093925	0.31625219784678	0.700649387476097
GO:0048185	activin binding	1/633	11/18639	0.0909090909090909	2.67686342093925	0.31625219784678	0.700649387476097
GO:0048407	platelet-derived growth factor binding	1/633	11/18639	0.0909090909090909	2.67686342093925	0.31625219784678	0.700649387476097
GO:0050998	nitric-oxide synthase binding	1/633	11/18639	0.0909090909090909	2.67686342093925	0.31625219784678	0.700649387476097
GO:0070697	activin receptor binding	1/633	11/18639	0.0909090909090909	2.67686342093925	0.31625219784678	0.700649387476097
GO:0070990	snRNP binding	1/633	11/18639	0.0909090909090909	2.67686342093925	0.31625219784678	0.700649387476097
GO:0097493	structural molecule activity conferring elasticity	1/633	11/18639	0.0909090909090909	2.67686342093925	0.31625219784678	0.700649387476097
GO:0140537	transcription regulator activator activity	1/633	11/18639	0.0909090909090909	2.67686342093925	0.31625219784678	0.700649387476097
GO:0180030	inositol phosphate kinase activity	1/633	11/18639	0.0909090909090909	2.67686342093925	0.31625219784678	0.700649387476097
GO:1990948	ubiquitin ligase inhibitor activity	1/633	11/18639	0.0909090909090909	2.67686342093925	0.31625219784678	0.700649387476097
GO:0141003	histone H2AX kinase activity	14/633	354/18639	0.0395480225988701	1.16451120571933	0.317949944870902	0.700649387476097
GO:0004676	3-phosphoinositide-dependent protein kinase activity	10/633	245/18639	0.0408163265306122	1.20185704613599	0.321697392289017	0.700649387476097
GO:0004711	ribosomal protein S6 kinase activity	10/633	245/18639	0.0408163265306122	1.20185704613599	0.321697392289017	0.700649387476097
GO:0035175	histone H3S10 kinase activity	10/633	245/18639	0.0408163265306122	1.20185704613599	0.321697392289017	0.700649387476097
GO:0035979	histone H2AXS139 kinase activity	10/633	245/18639	0.0408163265306122	1.20185704613599	0.321697392289017	0.700649387476097
GO:0044022	histone H3S28 kinase activity	10/633	245/18639	0.0408163265306122	1.20185704613599	0.321697392289017	0.700649387476097
GO:0044023	histone H4S1 kinase activity	10/633	245/18639	0.0408163265306122	1.20185704613599	0.321697392289017	0.700649387476097
GO:0044024	histone H2AS1 kinase activity	10/633	245/18639	0.0408163265306122	1.20185704613599	0.321697392289017	0.700649387476097
GO:0044025	histone H2BS14 kinase activity	10/633	245/18639	0.0408163265306122	1.20185704613599	0.321697392289017	0.700649387476097
GO:0072354	histone H3T3 kinase activity	10/633	245/18639	0.0408163265306122	1.20185704613599	0.321697392289017	0.700649387476097
GO:0072371	histone H2AS121 kinase activity	10/633	245/18639	0.0408163265306122	1.20185704613599	0.321697392289017	0.700649387476097
GO:0072518	Rho-dependent protein serine/threonine kinase activity	10/633	245/18639	0.0408163265306122	1.20185704613599	0.321697392289017	0.700649387476097
GO:0140823	histone H2BS36 kinase activity	10/633	245/18639	0.0408163265306122	1.20185704613599	0.321697392289017	0.700649387476097
GO:0140855	histone H3S57 kinase activity	10/633	245/18639	0.0408163265306122	1.20185704613599	0.321697392289017	0.700649387476097
GO:0140995	histone H2A kinase activity	10/633	245/18639	0.0408163265306122	1.20185704613599	0.321697392289017	0.700649387476097
GO:0140997	histone H4 kinase activity	10/633	245/18639	0.0408163265306122	1.20185704613599	0.321697392289017	0.700649387476097
GO:0140998	histone H2B kinase activity	10/633	245/18639	0.0408163265306122	1.20185704613599	0.321697392289017	0.700649387476097
GO:1990244	histone H2AT120 kinase activity	10/633	245/18639	0.0408163265306122	1.20185704613599	0.321697392289017	0.700649387476097
GO:0015035	protein-disulfide reductase activity	2/633	34/18639	0.0588235294117647	1.73208809590187	0.321922818291398	0.700649387476097
GO:0016831	carboxy-lyase activity	2/633	34/18639	0.0588235294117647	1.73208809590187	0.321922818291398	0.700649387476097
GO:0015081	sodium ion transmembrane transporter activity	7/633	164/18639	0.0426829268292683	1.25682002080684	0.323401036126778	0.700649387476097
GO:0004879	nuclear receptor activity	3/633	59/18639	0.0508474576271186	1.49722869306772	0.324302732378377	0.700649387476097
GO:1902936	phosphatidylinositol bisphosphate binding	5/633	111/18639	0.045045045045045	1.32637376713206	0.325312035017574	0.700649387476097
GO:0004677	DNA-dependent protein kinase activity	10/633	246/18639	0.040650406504065	1.19697144838747	0.32615573019525	0.700649387476097
GO:0016755	aminoacyltransferase activity	19/633	496/18639	0.0383064516129032	1.12795253019416	0.327683827132207	0.700649387476097
GO:0035402	histone H3T11 kinase activity	10/633	247/18639	0.0404858299595142	1.19212541013489	0.330626626523234	0.700649387476097
GO:0098531	ligand-modulated transcription factor activity	3/633	60/18639	0.05	1.47227488151659	0.333669230114081	0.700649387476097
GO:0004623	phospholipase A2 activity	2/633	35/18639	0.0571428571428571	1.68259986459039	0.334474648123669	0.700649387476097
GO:0005154	epidermal growth factor receptor binding	2/633	35/18639	0.0571428571428571	1.68259986459039	0.334474648123669	0.700649387476097
GO:0010485	histone H4 acetyltransferase activity	2/633	35/18639	0.0571428571428571	1.68259986459039	0.334474648123669	0.700649387476097
GO:0016229	steroid dehydrogenase activity	2/633	35/18639	0.0571428571428571	1.68259986459039	0.334474648123669	0.700649387476097
GO:0004679	AMP-activated protein kinase activity	10/633	248/18639	0.0403225806451613	1.18731845283596	0.335109418900635	0.700649387476097
GO:0003720	telomerase activity	1/633	12/18639	0.0833333333333333	2.45379146919431	0.339486702826541	0.700649387476097
GO:0004300	enoyl-CoA hydratase activity	1/633	12/18639	0.0833333333333333	2.45379146919431	0.339486702826541	0.700649387476097
GO:0005025	transforming growth factor beta receptor activity, type I	1/633	12/18639	0.0833333333333333	2.45379146919431	0.339486702826541	0.700649387476097
GO:0005026	transforming growth factor beta receptor activity, type II	1/633	12/18639	0.0833333333333333	2.45379146919431	0.339486702826541	0.700649387476097
GO:0005078	MAP-kinase scaffold activity	1/633	12/18639	0.0833333333333333	2.45379146919431	0.339486702826541	0.700649387476097
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	1/633	12/18639	0.0833333333333333	2.45379146919431	0.339486702826541	0.700649387476097
GO:0008504	monoamine transmembrane transporter activity	1/633	12/18639	0.0833333333333333	2.45379146919431	0.339486702826541	0.700649387476097
GO:0015166	polyol transmembrane transporter activity	1/633	12/18639	0.0833333333333333	2.45379146919431	0.339486702826541	0.700649387476097
GO:0015269	calcium-activated potassium channel activity	1/633	12/18639	0.0833333333333333	2.45379146919431	0.339486702826541	0.700649387476097
GO:0016208	AMP binding	1/633	12/18639	0.0833333333333333	2.45379146919431	0.339486702826541	0.700649387476097
GO:0016273	arginine N-methyltransferase activity	1/633	12/18639	0.0833333333333333	2.45379146919431	0.339486702826541	0.700649387476097
GO:0016274	protein-arginine N-methyltransferase activity	1/633	12/18639	0.0833333333333333	2.45379146919431	0.339486702826541	0.700649387476097
GO:0016361	activin receptor activity, type I	1/633	12/18639	0.0833333333333333	2.45379146919431	0.339486702826541	0.700649387476097
GO:0016362	activin receptor activity, type II	1/633	12/18639	0.0833333333333333	2.45379146919431	0.339486702826541	0.700649387476097
GO:0017002	activin receptor activity	1/633	12/18639	0.0833333333333333	2.45379146919431	0.339486702826541	0.700649387476097
GO:0031543	peptidyl-proline dioxygenase activity	1/633	12/18639	0.0833333333333333	2.45379146919431	0.339486702826541	0.700649387476097
GO:0034452	dynactin binding	1/633	12/18639	0.0833333333333333	2.45379146919431	0.339486702826541	0.700649387476097
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	1/633	12/18639	0.0833333333333333	2.45379146919431	0.339486702826541	0.700649387476097
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	1/633	12/18639	0.0833333333333333	2.45379146919431	0.339486702826541	0.700649387476097
GO:1990247	N6-methyladenosine-containing RNA reader activity	1/633	12/18639	0.0833333333333333	2.45379146919431	0.339486702826541	0.700649387476097
GO:1990817	poly(A) RNA polymerase activity	1/633	12/18639	0.0833333333333333	2.45379146919431	0.339486702826541	0.700649387476097
GO:0004713	protein tyrosine kinase activity	6/633	140/18639	0.0428571428571429	1.26194989844279	0.340106890170689	0.700649387476097
GO:0008081	phosphoric diester hydrolase activity	4/633	87/18639	0.0459770114942529	1.35381598300376	0.34235781645035	0.70193043132613
GO:0004033	aldo-keto reductase (NADPH) activity	2/633	36/18639	0.0555555555555556	1.63586097946288	0.34695740217267	0.70193043132613
GO:0005484	SNAP receptor activity	2/633	36/18639	0.0555555555555556	1.63586097946288	0.34695740217267	0.70193043132613
GO:0016409	palmitoyltransferase activity	2/633	36/18639	0.0555555555555556	1.63586097946288	0.34695740217267	0.70193043132613
GO:0044390	ubiquitin-like protein conjugating enzyme binding	2/633	36/18639	0.0555555555555556	1.63586097946288	0.34695740217267	0.70193043132613
GO:0045505	dynein intermediate chain binding	2/633	36/18639	0.0555555555555556	1.63586097946288	0.34695740217267	0.70193043132613
GO:0055106	ubiquitin-protein transferase regulator activity	2/633	36/18639	0.0555555555555556	1.63586097946288	0.34695740217267	0.70193043132613
GO:0101005	deubiquitinase activity	5/633	115/18639	0.0434782608695652	1.28023902740573	0.352291098034469	0.70193043132613
GO:0030246	carbohydrate binding	11/633	280/18639	0.0392857142857143	1.15678740690589	0.354222203568343	0.70193043132613
GO:0004842	ubiquitin-protein transferase activity	17/633	449/18639	0.0378619153674833	1.11486293923305	0.357679515911555	0.70193043132613
GO:0022829	wide pore channel activity	2/633	37/18639	0.0540540540540541	1.59164852055847	0.359361303244957	0.70193043132613
GO:0003964	RNA-directed DNA polymerase activity	1/633	13/18639	0.0769230769230769	2.26503827925629	0.361932878652536	0.70193043132613
GO:0004535	poly(A)-specific ribonuclease activity	1/633	13/18639	0.0769230769230769	2.26503827925629	0.361932878652536	0.70193043132613
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/633	13/18639	0.0769230769230769	2.26503827925629	0.361932878652536	0.70193043132613
GO:0004993	G protein-coupled serotonin receptor activity	1/633	13/18639	0.0769230769230769	2.26503827925629	0.361932878652536	0.70193043132613
GO:0005035	death receptor activity	1/633	13/18639	0.0769230769230769	2.26503827925629	0.361932878652536	0.70193043132613
GO:0017154	semaphorin receptor activity	1/633	13/18639	0.0769230769230769	2.26503827925629	0.361932878652536	0.70193043132613
GO:0019104	DNA N-glycosylase activity	1/633	13/18639	0.0769230769230769	2.26503827925629	0.361932878652536	0.70193043132613
GO:0019855	calcium channel inhibitor activity	1/633	13/18639	0.0769230769230769	2.26503827925629	0.361932878652536	0.70193043132613
GO:0035325	Toll-like receptor binding	1/633	13/18639	0.0769230769230769	2.26503827925629	0.361932878652536	0.70193043132613
GO:0035673	oligopeptide transmembrane transporter activity	1/633	13/18639	0.0769230769230769	2.26503827925629	0.361932878652536	0.70193043132613
GO:0043560	insulin receptor substrate binding	1/633	13/18639	0.0769230769230769	2.26503827925629	0.361932878652536	0.70193043132613
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/633	13/18639	0.0769230769230769	2.26503827925629	0.361932878652536	0.70193043132613
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	1/633	13/18639	0.0769230769230769	2.26503827925629	0.361932878652536	0.70193043132613
GO:0070123	transforming growth factor beta receptor activity, type III	1/633	13/18639	0.0769230769230769	2.26503827925629	0.361932878652536	0.70193043132613
GO:0070700	BMP receptor binding	1/633	13/18639	0.0769230769230769	2.26503827925629	0.361932878652536	0.70193043132613
GO:0097157	pre-mRNA intronic binding	1/633	13/18639	0.0769230769230769	2.26503827925629	0.361932878652536	0.70193043132613
GO:0140333	glycerophospholipid flippase activity	1/633	13/18639	0.0769230769230769	2.26503827925629	0.361932878652536	0.70193043132613
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/633	13/18639	0.0769230769230769	2.26503827925629	0.361932878652536	0.70193043132613
GO:0019955	cytokine binding	6/633	144/18639	0.0416666666666667	1.22689573459716	0.364361495987906	0.701983280927179
GO:0004536	DNA nuclease activity	3/633	64/18639	0.046875	1.3802577014218	0.371027375489929	0.701983280927179
GO:0005109	frizzled binding	2/633	38/18639	0.0526315789473684	1.54976303317536	0.371677315753009	0.701983280927179
GO:0005501	retinoid binding	2/633	38/18639	0.0526315789473684	1.54976303317536	0.371677315753009	0.701983280927179
GO:0019840	isoprenoid binding	2/633	38/18639	0.0526315789473684	1.54976303317536	0.371677315753009	0.701983280927179
GO:0042887	amide transmembrane transporter activity	2/633	38/18639	0.0526315789473684	1.54976303317536	0.371677315753009	0.701983280927179
GO:0043531	ADP binding	2/633	38/18639	0.0526315789473684	1.54976303317536	0.371677315753009	0.701983280927179
GO:0046982	protein heterodimerization activity	14/633	369/18639	0.037940379403794	1.1171733518283	0.37414622826588	0.701983280927179
GO:0015293	symporter activity	6/633	146/18639	0.0410958904109589	1.21008894371226	0.376526003697584	0.701983280927179
GO:0120013	lipid transfer activity	3/633	65/18639	0.0461538461538462	1.35902296755377	0.38031488259101	0.701983280927179
GO:0000287	magnesium ion binding	9/633	230/18639	0.0391304347826087	1.15221512466516	0.380425288010398	0.701983280927179
GO:0015085	calcium ion transmembrane transporter activity	6/633	147/18639	0.0408163265306122	1.20185704613599	0.382612237071983	0.701983280927179
GO:0005313	L-glutamate transmembrane transporter activity	1/633	14/18639	0.0714285714285714	2.10324983073798	0.38361743184769	0.701983280927179
GO:0005344	oxygen carrier activity	1/633	14/18639	0.0714285714285714	2.10324983073798	0.38361743184769	0.701983280927179
GO:0005545	1-phosphatidylinositol binding	1/633	14/18639	0.0714285714285714	2.10324983073798	0.38361743184769	0.701983280927179
GO:0008191	metalloendopeptidase inhibitor activity	1/633	14/18639	0.0714285714285714	2.10324983073798	0.38361743184769	0.701983280927179
GO:0008195	phosphatidate phosphatase activity	1/633	14/18639	0.0714285714285714	2.10324983073798	0.38361743184769	0.701983280927179
GO:0008474	palmitoyl-(protein) hydrolase activity	1/633	14/18639	0.0714285714285714	2.10324983073798	0.38361743184769	0.701983280927179
GO:0008559	ABC-type xenobiotic transporter activity	1/633	14/18639	0.0714285714285714	2.10324983073798	0.38361743184769	0.701983280927179
GO:0015386	potassium:proton antiporter activity	1/633	14/18639	0.0714285714285714	2.10324983073798	0.38361743184769	0.701983280927179
GO:0016530	metallochaperone activity	1/633	14/18639	0.0714285714285714	2.10324983073798	0.38361743184769	0.701983280927179
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	1/633	14/18639	0.0714285714285714	2.10324983073798	0.38361743184769	0.701983280927179
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/633	14/18639	0.0714285714285714	2.10324983073798	0.38361743184769	0.701983280927179
GO:0042043	neurexin family protein binding	1/633	14/18639	0.0714285714285714	2.10324983073798	0.38361743184769	0.701983280927179
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	1/633	14/18639	0.0714285714285714	2.10324983073798	0.38361743184769	0.701983280927179
GO:0061665	SUMO ligase activity	1/633	14/18639	0.0714285714285714	2.10324983073798	0.38361743184769	0.701983280927179
GO:0098599	palmitoyl hydrolase activity	1/633	14/18639	0.0714285714285714	2.10324983073798	0.38361743184769	0.701983280927179
GO:0098821	BMP receptor activity	1/633	14/18639	0.0714285714285714	2.10324983073798	0.38361743184769	0.701983280927179
GO:0000217	DNA secondary structure binding	2/633	39/18639	0.0512820512820513	1.51002551950419	0.383897106757051	0.701983280927179
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	2/633	39/18639	0.0512820512820513	1.51002551950419	0.383897106757051	0.701983280927179
GO:0008235	metalloexopeptidase activity	3/633	66/18639	0.0454545454545455	1.33843171046963	0.389572213441283	0.709823135539899
GO:0004540	RNA nuclease activity	5/633	121/18639	0.0413223140495868	1.21675610042693	0.392904372959349	0.709823135539899
GO:0015036	disulfide oxidoreductase activity	2/633	40/18639	0.05	1.47227488151659	0.396013008790884	0.709823135539899
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	2/633	40/18639	0.05	1.47227488151659	0.396013008790884	0.709823135539899
GO:0030331	nuclear estrogen receptor binding	2/633	40/18639	0.05	1.47227488151659	0.396013008790884	0.709823135539899
GO:0032451	demethylase activity	2/633	40/18639	0.05	1.47227488151659	0.396013008790884	0.709823135539899
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	2/633	40/18639	0.05	1.47227488151659	0.396013008790884	0.709823135539899
GO:0042562	hormone binding	4/633	94/18639	0.0425531914893617	1.25299989916305	0.39659029138861	0.709823135539899
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	5/633	122/18639	0.040983606557377	1.20678268976769	0.399663819327454	0.709823135539899
GO:0019842	vitamin binding	6/633	150/18639	0.04	1.17781990521327	0.400869166591486	0.709823135539899
GO:0000774	adenyl-nucleotide exchange factor activity	1/633	15/18639	0.0666666666666667	1.96303317535545	0.40456616557335	0.709823135539899
GO:0004129	cytochrome-c oxidase activity	1/633	15/18639	0.0666666666666667	1.96303317535545	0.40456616557335	0.709823135539899
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	1/633	15/18639	0.0666666666666667	1.96303317535545	0.40456616557335	0.709823135539899
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	1/633	15/18639	0.0666666666666667	1.96303317535545	0.40456616557335	0.709823135539899
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/633	15/18639	0.0666666666666667	1.96303317535545	0.40456616557335	0.709823135539899
GO:0015929	hexosaminidase activity	1/633	15/18639	0.0666666666666667	1.96303317535545	0.40456616557335	0.709823135539899
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/633	15/18639	0.0666666666666667	1.96303317535545	0.40456616557335	0.709823135539899
GO:0017081	chloride channel regulator activity	1/633	15/18639	0.0666666666666667	1.96303317535545	0.40456616557335	0.709823135539899
GO:0033130	acetylcholine receptor binding	1/633	15/18639	0.0666666666666667	1.96303317535545	0.40456616557335	0.709823135539899
GO:0034483	heparan sulfate sulfotransferase activity	1/633	15/18639	0.0666666666666667	1.96303317535545	0.40456616557335	0.709823135539899
GO:0042809	nuclear vitamin D receptor binding	1/633	15/18639	0.0666666666666667	1.96303317535545	0.40456616557335	0.709823135539899
GO:0048531	beta-1,3-galactosyltransferase activity	1/633	15/18639	0.0666666666666667	1.96303317535545	0.40456616557335	0.709823135539899
GO:0003777	microtubule motor activity	3/633	68/18639	0.0441176470588235	1.2990660719264	0.407979107501834	0.709823135539899
GO:0030145	manganese ion binding	3/633	68/18639	0.0441176470588235	1.2990660719264	0.407979107501834	0.709823135539899
GO:0017080	sodium channel regulator activity	2/633	41/18639	0.0487804878048781	1.43636573806496	0.408017984395799	0.709823135539899
GO:0002039	p53 binding	3/633	69/18639	0.0434782608695652	1.28023902740573	0.417120507277289	0.709823135539899
GO:0008080	N-acetyltransferase activity	3/633	69/18639	0.0434782608695652	1.28023902740573	0.417120507277289	0.709823135539899
GO:0004402	histone acetyltransferase activity	2/633	42/18639	0.0476190476190476	1.40216655382532	0.419905592289705	0.709823135539899
GO:0019894	kinesin binding	2/633	42/18639	0.0476190476190476	1.40216655382532	0.419905592289705	0.709823135539899
GO:0042056	chemoattractant activity	2/633	42/18639	0.0476190476190476	1.40216655382532	0.419905592289705	0.709823135539899
GO:0003688	DNA replication origin binding	1/633	16/18639	0.0625	1.84034360189573	0.424804010139075	0.709823135539899
GO:0005024	transforming growth factor beta receptor activity	1/633	16/18639	0.0625	1.84034360189573	0.424804010139075	0.709823135539899
GO:0005149	interleukin-1 receptor binding	1/633	16/18639	0.0625	1.84034360189573	0.424804010139075	0.709823135539899
GO:0005159	insulin-like growth factor receptor binding	1/633	16/18639	0.0625	1.84034360189573	0.424804010139075	0.709823135539899
GO:0005521	lamin binding	1/633	16/18639	0.0625	1.84034360189573	0.424804010139075	0.709823135539899
GO:0015378	sodium:chloride symporter activity	1/633	16/18639	0.0625	1.84034360189573	0.424804010139075	0.709823135539899
GO:0015385	sodium:proton antiporter activity	1/633	16/18639	0.0625	1.84034360189573	0.424804010139075	0.709823135539899
GO:0015562	efflux transmembrane transporter activity	1/633	16/18639	0.0625	1.84034360189573	0.424804010139075	0.709823135539899
GO:0016675	oxidoreductase activity, acting on a heme group of donors	1/633	16/18639	0.0625	1.84034360189573	0.424804010139075	0.709823135539899
GO:0016722	oxidoreductase activity, acting on metal ions	1/633	16/18639	0.0625	1.84034360189573	0.424804010139075	0.709823135539899
GO:0017070	U6 snRNA binding	1/633	16/18639	0.0625	1.84034360189573	0.424804010139075	0.709823135539899
GO:0019841	retinol binding	1/633	16/18639	0.0625	1.84034360189573	0.424804010139075	0.709823135539899
GO:0022841	potassium ion leak channel activity	1/633	16/18639	0.0625	1.84034360189573	0.424804010139075	0.709823135539899
GO:0031435	mitogen-activated protein kinase kinase kinase binding	1/633	16/18639	0.0625	1.84034360189573	0.424804010139075	0.709823135539899
GO:0034450	ubiquitin-ubiquitin ligase activity	1/633	16/18639	0.0625	1.84034360189573	0.424804010139075	0.709823135539899
GO:0043023	ribosomal large subunit binding	1/633	16/18639	0.0625	1.84034360189573	0.424804010139075	0.709823135539899
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/633	16/18639	0.0625	1.84034360189573	0.424804010139075	0.709823135539899
GO:0140327	flippase activity	1/633	16/18639	0.0625	1.84034360189573	0.424804010139075	0.709823135539899
GO:0140328	floppase activity	1/633	16/18639	0.0625	1.84034360189573	0.424804010139075	0.709823135539899
GO:0005506	iron ion binding	6/633	154/18639	0.038961038961039	1.14722718040254	0.425154482224419	0.709823135539899
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	10/633	268/18639	0.0373134328358209	1.09871259814671	0.426254236404585	0.710423727340976
GO:0008514	organic anion transmembrane transporter activity	10/633	269/18639	0.0371747211895911	1.09462816469635	0.430836546020815	0.71572220534979
GO:0004712	protein serine/threonine/tyrosine kinase activity	2/633	43/18639	0.0465116279069767	1.36955802931776	0.431669955101592	0.71572220534979
GO:0008200	ion channel inhibitor activity	2/633	43/18639	0.0465116279069767	1.36955802931776	0.431669955101592	0.71572220534979
GO:0019783	ubiquitin-like protein peptidase activity	5/633	127/18639	0.0393700787401575	1.15927156024928	0.433306163767975	0.716942605687815
GO:0003779	actin binding	16/633	443/18639	0.036117381489842	1.06349427107293	0.436572437610172	0.716942605687815
GO:0005539	glycosaminoglycan binding	9/633	242/18639	0.0371900826446281	1.09508049038424	0.438618865974366	0.716942605687815
GO:0031490	chromatin DNA binding	5/633	128/18639	0.0390625	1.15021475118483	0.439991169406141	0.716942605687815
GO:0016248	channel inhibitor activity	2/633	44/18639	0.0454545454545455	1.33843171046963	0.443305728604303	0.716942605687815
GO:0016790	thiolester hydrolase activity	2/633	44/18639	0.0454545454545455	1.33843171046963	0.443305728604303	0.716942605687815
GO:0019205	nucleobase-containing compound kinase activity	2/633	44/18639	0.0454545454545455	1.33843171046963	0.443305728604303	0.716942605687815
GO:0004029	aldehyde dehydrogenase (NAD+) activity	1/633	17/18639	0.0588235294117647	1.73208809590187	0.444355052483594	0.716942605687815
GO:0004550	nucleoside diphosphate kinase activity	1/633	17/18639	0.0588235294117647	1.73208809590187	0.444355052483594	0.716942605687815
GO:0005092	GDP-dissociation inhibitor activity	1/633	17/18639	0.0588235294117647	1.73208809590187	0.444355052483594	0.716942605687815
GO:0008429	phosphatidylethanolamine binding	1/633	17/18639	0.0588235294117647	1.73208809590187	0.444355052483594	0.716942605687815
GO:0009881	photoreceptor activity	1/633	17/18639	0.0588235294117647	1.73208809590187	0.444355052483594	0.716942605687815
GO:0015278	intracellularly gated calcium channel activity	1/633	17/18639	0.0588235294117647	1.73208809590187	0.444355052483594	0.716942605687815
GO:0016805	dipeptidase activity	1/633	17/18639	0.0588235294117647	1.73208809590187	0.444355052483594	0.716942605687815
GO:0030548	acetylcholine receptor regulator activity	1/633	17/18639	0.0588235294117647	1.73208809590187	0.444355052483594	0.716942605687815
GO:0048038	quinone binding	1/633	17/18639	0.0588235294117647	1.73208809590187	0.444355052483594	0.716942605687815
GO:0004521	RNA endonuclease activity	3/633	73/18639	0.0410958904109589	1.21008894371226	0.453185507842714	0.72311034483754
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	5/633	130/18639	0.0384615384615385	1.13251913962814	0.453304163297132	0.72311034483754
GO:0106310	protein serine kinase activity	13/633	361/18639	0.03601108033241	1.06036418059366	0.454495644153474	0.72311034483754
GO:0008009	chemokine activity	2/633	45/18639	0.0444444444444444	1.3086887835703	0.454808072381286	0.72311034483754
GO:0141110	transporter inhibitor activity	2/633	45/18639	0.0444444444444444	1.3086887835703	0.454808072381286	0.72311034483754
GO:0015079	potassium ion transmembrane transporter activity	6/633	160/18639	0.0375	1.10420616113744	0.461284849755931	0.72311034483754
GO:0003684	damaged DNA binding	3/633	74/18639	0.0405405405405405	1.19373639041885	0.462059699498885	0.72311034483754
GO:0003746	translation elongation factor activity	1/633	18/18639	0.0555555555555556	1.63586097946288	0.463242564661549	0.72311034483754
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	1/633	18/18639	0.0555555555555556	1.63586097946288	0.463242564661549	0.72311034483754
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/633	18/18639	0.0555555555555556	1.63586097946288	0.463242564661549	0.72311034483754
GO:0004970	glutamate-gated receptor activity	1/633	18/18639	0.0555555555555556	1.63586097946288	0.463242564661549	0.72311034483754
GO:0008409	5'-3' exonuclease activity	1/633	18/18639	0.0555555555555556	1.63586097946288	0.463242564661549	0.72311034483754
GO:0015373	monoatomic anion:sodium symporter activity	1/633	18/18639	0.0555555555555556	1.63586097946288	0.463242564661549	0.72311034483754
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/633	18/18639	0.0555555555555556	1.63586097946288	0.463242564661549	0.72311034483754
GO:0031690	adrenergic receptor binding	1/633	18/18639	0.0555555555555556	1.63586097946288	0.463242564661549	0.72311034483754
GO:0034185	apolipoprotein binding	1/633	18/18639	0.0555555555555556	1.63586097946288	0.463242564661549	0.72311034483754
GO:0035615	clathrin adaptor activity	1/633	18/18639	0.0555555555555556	1.63586097946288	0.463242564661549	0.72311034483754
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/633	18/18639	0.0555555555555556	1.63586097946288	0.463242564661549	0.72311034483754
GO:0098641	cadherin binding involved in cell-cell adhesion	1/633	18/18639	0.0555555555555556	1.63586097946288	0.463242564661549	0.72311034483754
GO:0099602	neurotransmitter receptor regulator activity	1/633	18/18639	0.0555555555555556	1.63586097946288	0.463242564661549	0.72311034483754
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	2/633	46/18639	0.0434782608695652	1.28023902740573	0.466172621865683	0.724151645616595
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	2/633	46/18639	0.0434782608695652	1.28023902740573	0.466172621865683	0.724151645616595
GO:0030291	protein serine/threonine kinase inhibitor activity	2/633	46/18639	0.0434782608695652	1.28023902740573	0.466172621865683	0.724151645616595
GO:0019003	GDP binding	3/633	75/18639	0.04	1.17781990521327	0.470870887235781	0.72420898481485
GO:0001217	DNA-binding transcription repressor activity	10/633	278/18639	0.0359712230215827	1.05919056224215	0.471909733189061	0.72420898481485
GO:0005504	fatty acid binding	2/633	47/18639	0.0425531914893617	1.25299989916305	0.477395461692599	0.72420898481485
GO:0043495	protein-membrane adaptor activity	2/633	47/18639	0.0425531914893617	1.25299989916305	0.477395461692599	0.72420898481485
GO:0061733	protein-lysine-acetyltransferase activity	2/633	47/18639	0.0425531914893617	1.25299989916305	0.477395461692599	0.72420898481485
GO:0061749	forked DNA-dependent helicase activity	2/633	47/18639	0.0425531914893617	1.25299989916305	0.477395461692599	0.72420898481485
GO:1990518	single-stranded 3'-5' DNA helicase activity	2/633	47/18639	0.0425531914893617	1.25299989916305	0.477395461692599	0.72420898481485
GO:0003756	protein disulfide isomerase activity	1/633	19/18639	0.0526315789473684	1.54976303317536	0.481489031369526	0.72420898481485
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	1/633	19/18639	0.0526315789473684	1.54976303317536	0.481489031369526	0.72420898481485
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	1/633	19/18639	0.0526315789473684	1.54976303317536	0.481489031369526	0.72420898481485
GO:0016918	retinal binding	1/633	19/18639	0.0526315789473684	1.54976303317536	0.481489031369526	0.72420898481485
GO:0022821	solute:potassium antiporter activity	1/633	19/18639	0.0526315789473684	1.54976303317536	0.481489031369526	0.72420898481485
GO:0022840	leak channel activity	1/633	19/18639	0.0526315789473684	1.54976303317536	0.481489031369526	0.72420898481485
GO:0022842	narrow pore channel activity	1/633	19/18639	0.0526315789473684	1.54976303317536	0.481489031369526	0.72420898481485
GO:0042577	lipid phosphatase activity	1/633	19/18639	0.0526315789473684	1.54976303317536	0.481489031369526	0.72420898481485
GO:0043395	heparan sulfate proteoglycan binding	1/633	19/18639	0.0526315789473684	1.54976303317536	0.481489031369526	0.72420898481485
GO:0099589	serotonin receptor activity	1/633	19/18639	0.0526315789473684	1.54976303317536	0.481489031369526	0.72420898481485
GO:0140036	ubiquitin-modified protein reader activity	1/633	19/18639	0.0526315789473684	1.54976303317536	0.481489031369526	0.72420898481485
GO:0000149	SNARE binding	4/633	106/18639	0.0377358490566038	1.11115085397478	0.487306206262641	0.72420898481485
GO:0008013	beta-catenin binding	4/633	106/18639	0.0377358490566038	1.11115085397478	0.487306206262641	0.72420898481485
GO:0009378	four-way junction helicase activity	2/633	48/18639	0.0416666666666667	1.22689573459716	0.488473100307814	0.72420898481485
GO:0036121	double-stranded DNA helicase activity	2/633	48/18639	0.0416666666666667	1.22689573459716	0.488473100307814	0.72420898481485
GO:0043138	3'-5' DNA helicase activity	2/633	48/18639	0.0416666666666667	1.22689573459716	0.488473100307814	0.72420898481485
GO:0140789	histone phosphatase activity	5/633	136/18639	0.0367647058823529	1.08255505993867	0.492675276530933	0.72420898481485
GO:0019199	transmembrane receptor protein kinase activity	3/633	78/18639	0.0384615384615385	1.13251913962814	0.496899117875133	0.72420898481485
GO:0000339	RNA cap binding	1/633	20/18639	0.05	1.47227488151659	0.499116176543698	0.72420898481485
GO:0001614	purinergic nucleotide receptor activity	1/633	20/18639	0.05	1.47227488151659	0.499116176543698	0.72420898481485
GO:0015095	magnesium ion transmembrane transporter activity	1/633	20/18639	0.05	1.47227488151659	0.499116176543698	0.72420898481485
GO:0016004	phospholipase activator activity	1/633	20/18639	0.05	1.47227488151659	0.499116176543698	0.72420898481485
GO:0016502	nucleotide receptor activity	1/633	20/18639	0.05	1.47227488151659	0.499116176543698	0.72420898481485
GO:0030742	GTP-dependent protein binding	1/633	20/18639	0.05	1.47227488151659	0.499116176543698	0.72420898481485
GO:0031418	L-ascorbic acid binding	1/633	20/18639	0.05	1.47227488151659	0.499116176543698	0.72420898481485
GO:0042288	MHC class I protein binding	1/633	20/18639	0.05	1.47227488151659	0.499116176543698	0.72420898481485
GO:0005004	GPI-linked ephrin receptor activity	2/633	49/18639	0.0408163265306122	1.20185704613599	0.499402445778574	0.72420898481485
GO:0005008	hepatocyte growth factor receptor activity	2/633	49/18639	0.0408163265306122	1.20185704613599	0.499402445778574	0.72420898481485
GO:0005009	insulin receptor activity	2/633	49/18639	0.0408163265306122	1.20185704613599	0.499402445778574	0.72420898481485
GO:0005011	macrophage colony-stimulating factor receptor activity	2/633	49/18639	0.0408163265306122	1.20185704613599	0.499402445778574	0.72420898481485
GO:0005018	platelet-derived growth factor alpha-receptor activity	2/633	49/18639	0.0408163265306122	1.20185704613599	0.499402445778574	0.72420898481485
GO:0005020	stem cell factor receptor activity	2/633	49/18639	0.0408163265306122	1.20185704613599	0.499402445778574	0.72420898481485
GO:0008288	boss receptor activity	2/633	49/18639	0.0408163265306122	1.20185704613599	0.499402445778574	0.72420898481485
GO:0016763	pentosyltransferase activity	2/633	49/18639	0.0408163265306122	1.20185704613599	0.499402445778574	0.72420898481485
GO:0036332	placental growth factor receptor activity	2/633	49/18639	0.0408163265306122	1.20185704613599	0.499402445778574	0.72420898481485
GO:0038062	protein tyrosine kinase collagen receptor activity	2/633	49/18639	0.0408163265306122	1.20185704613599	0.499402445778574	0.72420898481485
GO:0060175	brain-derived neurotrophic factor receptor activity	2/633	49/18639	0.0408163265306122	1.20185704613599	0.499402445778574	0.72420898481485
GO:0061134	peptidase regulator activity	8/633	226/18639	0.0353982300884956	1.04231850018873	0.50312101534494	0.728501017694031
GO:0015370	solute:sodium symporter activity	3/633	79/18639	0.0379746835443038	1.1181834543164	0.505431743555152	0.728675278673458
GO:0003713	transcription coactivator activity	9/633	256/18639	0.03515625	1.03519327606635	0.505663188651524	0.728675278673458
GO:0005201	extracellular matrix structural constituent	6/633	168/18639	0.0357142857142857	1.05162491536899	0.508493297740249	0.728675278673458
GO:0004620	phospholipase activity	4/633	109/18639	0.036697247706422	1.08056872037915	0.50915940642355	0.728675278673458
GO:0005006	epidermal growth factor receptor activity	2/633	50/18639	0.04	1.17781990521327	0.510180782754277	0.728675278673458
GO:0005007	fibroblast growth factor receptor activity	2/633	50/18639	0.04	1.17781990521327	0.510180782754277	0.728675278673458
GO:0005017	platelet-derived growth factor receptor activity	2/633	50/18639	0.04	1.17781990521327	0.510180782754277	0.728675278673458
GO:0005019	platelet-derived growth factor beta-receptor activity	2/633	50/18639	0.04	1.17781990521327	0.510180782754277	0.728675278673458
GO:0140767	enzyme-substrate adaptor activity	5/633	139/18639	0.0359712230215827	1.05919056224215	0.51197072124808	0.728675278673458
GO:0001846	opsonin binding	1/633	21/18639	0.0476190476190476	1.40216655382532	0.516144989060366	0.728675278673458
GO:0005248	voltage-gated sodium channel activity	1/633	21/18639	0.0476190476190476	1.40216655382532	0.516144989060366	0.728675278673458
GO:0009931	calcium-dependent protein serine/threonine kinase activity	1/633	21/18639	0.0476190476190476	1.40216655382532	0.516144989060366	0.728675278673458
GO:0010314	phosphatidylinositol-5-phosphate binding	1/633	21/18639	0.0476190476190476	1.40216655382532	0.516144989060366	0.728675278673458
GO:0019200	carbohydrate kinase activity	1/633	21/18639	0.0476190476190476	1.40216655382532	0.516144989060366	0.728675278673458
GO:0035613	RNA stem-loop binding	1/633	21/18639	0.0476190476190476	1.40216655382532	0.516144989060366	0.728675278673458
GO:0051010	microtubule plus-end binding	1/633	21/18639	0.0476190476190476	1.40216655382532	0.516144989060366	0.728675278673458
GO:0140312	cargo adaptor activity	1/633	21/18639	0.0476190476190476	1.40216655382532	0.516144989060366	0.728675278673458
GO:0005010	insulin-like growth factor receptor activity	2/633	51/18639	0.0392156862745098	1.15472539726791	0.52080575052706	0.730955439336224
GO:0005021	vascular endothelial growth factor receptor activity	2/633	51/18639	0.0392156862745098	1.15472539726791	0.52080575052706	0.730955439336224
GO:0005030	neurotrophin receptor activity	2/633	51/18639	0.0392156862745098	1.15472539726791	0.52080575052706	0.730955439336224
GO:0016597	amino acid binding	2/633	51/18639	0.0392156862745098	1.15472539726791	0.52080575052706	0.730955439336224
GO:0016829	lyase activity	7/633	200/18639	0.035	1.03059241706161	0.521626723997812	0.731023187857637
GO:0005085	guanyl-nucleotide exchange factor activity	8/633	230/18639	0.0347826086956522	1.02419122192458	0.523068673721123	0.731023187857637
GO:0005543	phospholipid binding	17/633	497/18639	0.03420523138833	1.00719005979002	0.523138468810622	0.731023187857637
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	2/633	52/18639	0.0384615384615385	1.13251913962814	0.531275322144327	0.733560857484662
GO:0008201	heparin binding	6/633	172/18639	0.0348837209302326	1.02716852198832	0.531528188924681	0.733560857484662
GO:0008093	cytoskeletal anchor activity	1/633	22/18639	0.0454545454545455	1.33843171046963	0.532595747569593	0.733560857484662
GO:0008970	phospholipase A1 activity	1/633	22/18639	0.0454545454545455	1.33843171046963	0.532595747569593	0.733560857484662
GO:0015377	chloride:monoatomic cation symporter activity	1/633	22/18639	0.0454545454545455	1.33843171046963	0.532595747569593	0.733560857484662
GO:0031683	G-protein beta/gamma-subunit complex binding	1/633	22/18639	0.0454545454545455	1.33843171046963	0.532595747569593	0.733560857484662
GO:0033691	sialic acid binding	1/633	22/18639	0.0454545454545455	1.33843171046963	0.532595747569593	0.733560857484662
GO:0061133	endopeptidase activator activity	1/633	22/18639	0.0454545454545455	1.33843171046963	0.532595747569593	0.733560857484662
GO:0070034	telomerase RNA binding	1/633	22/18639	0.0454545454545455	1.33843171046963	0.532595747569593	0.733560857484662
GO:0140035	ubiquitin-like protein reader activity	1/633	22/18639	0.0454545454545455	1.33843171046963	0.532595747569593	0.733560857484662
GO:0005003	ephrin receptor activity	2/633	53/18639	0.0377358490566038	1.11115085397478	0.541587784527273	0.733617798849381
GO:0005005	transmembrane-ephrin receptor activity	2/633	53/18639	0.0377358490566038	1.11115085397478	0.541587784527273	0.733617798849381
GO:0005544	calcium-dependent phospholipid binding	2/633	53/18639	0.0377358490566038	1.11115085397478	0.541587784527273	0.733617798849381
GO:0008146	sulfotransferase activity	2/633	53/18639	0.0377358490566038	1.11115085397478	0.541587784527273	0.733617798849381
GO:0034212	protein N-acetyltransferase activity	2/633	53/18639	0.0377358490566038	1.11115085397478	0.541587784527273	0.733617798849381
GO:0038064	collagen receptor activity	2/633	53/18639	0.0377358490566038	1.11115085397478	0.541587784527273	0.733617798849381
GO:0051018	protein kinase A binding	2/633	53/18639	0.0377358490566038	1.11115085397478	0.541587784527273	0.733617798849381
GO:0005158	insulin receptor binding	1/633	23/18639	0.0434782608695652	1.28023902740573	0.548488044491141	0.733617798849381
GO:0005212	structural constituent of eye lens	1/633	23/18639	0.0434782608695652	1.28023902740573	0.548488044491141	0.733617798849381
GO:0005283	amino acid:sodium symporter activity	1/633	23/18639	0.0434782608695652	1.28023902740573	0.548488044491141	0.733617798849381
GO:0016849	phosphorus-oxygen lyase activity	1/633	23/18639	0.0434782608695652	1.28023902740573	0.548488044491141	0.733617798849381
GO:0043274	phospholipase binding	1/633	23/18639	0.0434782608695652	1.28023902740573	0.548488044491141	0.733617798849381
GO:0070577	lysine-acetylated histone binding	1/633	23/18639	0.0434782608695652	1.28023902740573	0.548488044491141	0.733617798849381
GO:0099186	structural constituent of postsynapse	1/633	23/18639	0.0434782608695652	1.28023902740573	0.548488044491141	0.733617798849381
GO:0140103	catalytic activity, acting on a glycoprotein	1/633	23/18639	0.0434782608695652	1.28023902740573	0.548488044491141	0.733617798849381
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	1/633	23/18639	0.0434782608695652	1.28023902740573	0.548488044491141	0.733617798849381
GO:0004721	phosphoprotein phosphatase activity	6/633	175/18639	0.0342857142857143	1.00955991875423	0.548505719270077	0.733617798849381
GO:0001221	transcription coregulator binding	4/633	115/18639	0.0347826086956522	1.02419122192458	0.551536778487108	0.733617798849381
GO:0017124	SH3 domain binding	4/633	115/18639	0.0347826086956522	1.02419122192458	0.551536778487108	0.733617798849381
GO:0035401	histone H3Y41 kinase activity	4/633	115/18639	0.0347826086956522	1.02419122192458	0.551536778487108	0.733617798849381
GO:0140801	histone H2AXY142 kinase activity	4/633	115/18639	0.0347826086956522	1.02419122192458	0.551536778487108	0.733617798849381
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	2/633	54/18639	0.037037037037037	1.09057398630858	0.551741719551305	0.733617798849381
GO:0017069	snRNA binding	2/633	54/18639	0.037037037037037	1.09057398630858	0.551741719551305	0.733617798849381
GO:0051287	NAD binding	2/633	54/18639	0.037037037037037	1.09057398630858	0.551741719551305	0.733617798849381
GO:0140463	chromatin-protein adaptor activity	2/633	54/18639	0.037037037037037	1.09057398630858	0.551741719551305	0.733617798849381
GO:0140098	catalytic activity, acting on RNA	13/633	387/18639	0.0335917312661499	0.989125243396157	0.555958842514961	0.737448469799558
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	3/633	86/18639	0.0348837209302326	1.02716852198832	0.562938911505779	0.737448469799558
GO:0005315	phosphate transmembrane transporter activity	1/633	24/18639	0.0416666666666667	1.22689573459716	0.563840809200912	0.737448469799558
GO:0005540	hyaluronic acid binding	1/633	24/18639	0.0416666666666667	1.22689573459716	0.563840809200912	0.737448469799558
GO:0015149	hexose transmembrane transporter activity	1/633	24/18639	0.0416666666666667	1.22689573459716	0.563840809200912	0.737448469799558
GO:0019957	C-C chemokine binding	1/633	24/18639	0.0416666666666667	1.22689573459716	0.563840809200912	0.737448469799558
GO:0030552	cAMP binding	1/633	24/18639	0.0416666666666667	1.22689573459716	0.563840809200912	0.737448469799558
GO:0035035	histone acetyltransferase binding	1/633	24/18639	0.0416666666666667	1.22689573459716	0.563840809200912	0.737448469799558
GO:0055056	D-glucose transmembrane transporter activity	1/633	24/18639	0.0416666666666667	1.22689573459716	0.563840809200912	0.737448469799558
GO:0060229	lipase activator activity	1/633	24/18639	0.0416666666666667	1.22689573459716	0.563840809200912	0.737448469799558
GO:0070840	dynein complex binding	1/633	24/18639	0.0416666666666667	1.22689573459716	0.563840809200912	0.737448469799558
GO:0140033	acetylation-dependent protein binding	1/633	24/18639	0.0416666666666667	1.22689573459716	0.563840809200912	0.737448469799558
GO:0046873	metal ion transmembrane transporter activity	15/633	450/18639	0.0333333333333333	0.981516587677725	0.566776502980863	0.740279514097454
GO:0030170	pyridoxal phosphate binding	2/633	56/18639	0.0357142857142857	1.05162491536899	0.571569702675167	0.745525699141523
GO:0008483	transaminase activity	1/633	25/18639	0.04	1.17781990521327	0.578672330435176	0.750548813918573
GO:0015296	monoatomic anion:monoatomic cation symporter activity	1/633	25/18639	0.04	1.17781990521327	0.578672330435176	0.750548813918573
GO:0042974	nuclear retinoic acid receptor binding	1/633	25/18639	0.04	1.17781990521327	0.578672330435176	0.750548813918573
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	1/633	25/18639	0.04	1.17781990521327	0.578672330435176	0.750548813918573
GO:0042578	phosphoric ester hydrolase activity	12/633	363/18639	0.0330578512396694	0.973404880341545	0.579329865743398	0.750548813918573
GO:0070279	vitamin B6 binding	2/633	57/18639	0.0350877192982456	1.03317535545024	0.581242231654974	0.751029375753767
GO:0008408	3'-5' exonuclease activity	2/633	58/18639	0.0344827586206897	1.01536198725282	0.590753163278358	0.751029375753767
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	2/633	58/18639	0.0344827586206897	1.01536198725282	0.590753163278358	0.751029375753767
GO:0017116	single-stranded DNA helicase activity	2/633	58/18639	0.0344827586206897	1.01536198725282	0.590753163278358	0.751029375753767
GO:0005126	cytokine receptor binding	9/633	275/18639	0.0327272727272727	0.96367083153813	0.592311610571638	0.751029375753767
GO:0005112	Notch binding	1/633	26/18639	0.0384615384615385	1.13251913962814	0.593000277938912	0.751029375753767
GO:0005227	calcium-activated cation channel activity	1/633	26/18639	0.0384615384615385	1.13251913962814	0.593000277938912	0.751029375753767
GO:0008066	glutamate receptor activity	1/633	26/18639	0.0384615384615385	1.13251913962814	0.593000277938912	0.751029375753767
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	1/633	26/18639	0.0384615384615385	1.13251913962814	0.593000277938912	0.751029375753767
GO:0008157	protein phosphatase 1 binding	1/633	26/18639	0.0384615384615385	1.13251913962814	0.593000277938912	0.751029375753767
GO:0015145	monosaccharide transmembrane transporter activity	1/633	26/18639	0.0384615384615385	1.13251913962814	0.593000277938912	0.751029375753767
GO:0015216	purine nucleotide transmembrane transporter activity	1/633	26/18639	0.0384615384615385	1.13251913962814	0.593000277938912	0.751029375753767
GO:0030507	spectrin binding	1/633	26/18639	0.0384615384615385	1.13251913962814	0.593000277938912	0.751029375753767
GO:0034237	protein kinase A regulatory subunit binding	1/633	26/18639	0.0384615384615385	1.13251913962814	0.593000277938912	0.751029375753767
GO:0051139	metal cation:proton antiporter activity	1/633	26/18639	0.0384615384615385	1.13251913962814	0.593000277938912	0.751029375753767
GO:0097602	cullin family protein binding	1/633	26/18639	0.0384615384615385	1.13251913962814	0.593000277938912	0.751029375753767
GO:0120014	phospholipid transfer activity	1/633	26/18639	0.0384615384615385	1.13251913962814	0.593000277938912	0.751029375753767
GO:0031593	polyubiquitin modification-dependent protein binding	2/633	59/18639	0.0338983050847458	0.998152462045144	0.600102301204672	0.758023959416428
GO:0070888	E-box binding	2/633	59/18639	0.0338983050847458	0.998152462045144	0.600102301204672	0.758023959416428
GO:1901981	phosphatidylinositol phosphate binding	6/633	185/18639	0.0324324324324324	0.954989112335084	0.602961087445496	0.760532708157173
GO:0008266	poly(U) RNA binding	1/633	27/18639	0.037037037037037	1.09057398630858	0.606841723383744	0.760532708157173
GO:0015252	proton channel activity	1/633	27/18639	0.037037037037037	1.09057398630858	0.606841723383744	0.760532708157173
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	1/633	27/18639	0.037037037037037	1.09057398630858	0.606841723383744	0.760532708157173
GO:0035255	ionotropic glutamate receptor binding	1/633	27/18639	0.037037037037037	1.09057398630858	0.606841723383744	0.760532708157173
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	1/633	27/18639	0.037037037037037	1.09057398630858	0.606841723383744	0.760532708157173
GO:0004714	transmembrane receptor protein tyrosine kinase activity	2/633	60/18639	0.0333333333333333	0.981516587677725	0.609289648483658	0.761612060604573
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	2/633	60/18639	0.0333333333333333	0.981516587677725	0.609289648483658	0.761612060604573
GO:0005267	potassium channel activity	4/633	124/18639	0.032258064516129	0.949854762268766	0.611266315692642	0.763089288771048
GO:0051219	phosphoprotein binding	3/633	93/18639	0.032258064516129	0.949854762268766	0.616192483030301	0.764319170933083
GO:0015026	coreceptor activity	2/633	61/18639	0.0327868852459016	0.965426151814156	0.618315394279937	0.764319170933083
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	2/633	61/18639	0.0327868852459016	0.965426151814156	0.618315394279937	0.764319170933083
GO:0016836	hydro-lyase activity	2/633	61/18639	0.0327868852459016	0.965426151814156	0.618315394279937	0.764319170933083
GO:0019905	syntaxin binding	2/633	61/18639	0.0327868852459016	0.965426151814156	0.618315394279937	0.764319170933083
GO:0005242	inward rectifier potassium channel activity	1/633	28/18639	0.0357142857142857	1.05162491536899	0.620213160580074	0.764319170933083
GO:0046875	ephrin receptor binding	1/633	28/18639	0.0357142857142857	1.05162491536899	0.620213160580074	0.764319170933083
GO:0050698	proteoglycan sulfotransferase activity	1/633	28/18639	0.0357142857142857	1.05162491536899	0.620213160580074	0.764319170933083
GO:0051119	sugar transmembrane transporter activity	1/633	28/18639	0.0357142857142857	1.05162491536899	0.620213160580074	0.764319170933083
GO:0141052	histone H3 demethylase activity	1/633	28/18639	0.0357142857142857	1.05162491536899	0.620213160580074	0.764319170933083
GO:0016410	N-acyltransferase activity	3/633	94/18639	0.0319148936170213	0.93974992437229	0.623432115721785	0.767301065503736
GO:0008276	protein methyltransferase activity	3/633	95/18639	0.0315789473684211	0.929857819905213	0.630577844588576	0.770348927765386
GO:0035091	phosphatidylinositol binding	9/633	284/18639	0.0316901408450704	0.933131967158401	0.630758557804255	0.770348927765386
GO:0051020	GTPase binding	10/633	315/18639	0.0317460317460317	0.934777702550214	0.630815405504698	0.770348927765386
GO:0004181	metallocarboxypeptidase activity	1/633	29/18639	0.0344827586206897	1.01536198725282	0.633130525007177	0.770348927765386
GO:0004629	phospholipase C activity	1/633	29/18639	0.0344827586206897	1.01536198725282	0.633130525007177	0.770348927765386
GO:0005416	amino acid:monoatomic cation symporter activity	1/633	29/18639	0.0344827586206897	1.01536198725282	0.633130525007177	0.770348927765386
GO:0035250	UDP-galactosyltransferase activity	1/633	29/18639	0.0344827586206897	1.01536198725282	0.633130525007177	0.770348927765386
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	1/633	29/18639	0.0344827586206897	1.01536198725282	0.633130525007177	0.770348927765386
GO:0051861	glycolipid binding	1/633	29/18639	0.0344827586206897	1.01536198725282	0.633130525007177	0.770348927765386
GO:0016407	acetyltransferase activity	3/633	96/18639	0.03125	0.920171800947867	0.637629260666913	0.773763850408098
GO:0015291	secondary active transmembrane transporter activity	9/633	287/18639	0.0313588850174216	0.923377974470334	0.643134612019003	0.773763850408098
GO:0001965	G-protein alpha-subunit binding	1/633	30/18639	0.0333333333333333	0.981516587677725	0.645609212684257	0.773763850408098
GO:0001968	fibronectin binding	1/633	30/18639	0.0333333333333333	0.981516587677725	0.645609212684257	0.773763850408098
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	1/633	30/18639	0.0333333333333333	0.981516587677725	0.645609212684257	0.773763850408098
GO:0008187	poly-pyrimidine tract binding	1/633	30/18639	0.0333333333333333	0.981516587677725	0.645609212684257	0.773763850408098
GO:0015215	nucleotide transmembrane transporter activity	1/633	30/18639	0.0333333333333333	0.981516587677725	0.645609212684257	0.773763850408098
GO:0022839	monoatomic ion-gated channel activity	1/633	30/18639	0.0333333333333333	0.981516587677725	0.645609212684257	0.773763850408098
GO:0031624	ubiquitin conjugating enzyme binding	1/633	30/18639	0.0333333333333333	0.981516587677725	0.645609212684257	0.773763850408098
GO:0032452	histone demethylase activity	1/633	30/18639	0.0333333333333333	0.981516587677725	0.645609212684257	0.773763850408098
GO:0051721	protein phosphatase 2A binding	1/633	30/18639	0.0333333333333333	0.981516587677725	0.645609212684257	0.773763850408098
GO:0098918	structural constituent of synapse	1/633	30/18639	0.0333333333333333	0.981516587677725	0.645609212684257	0.773763850408098
GO:0016298	lipase activity	4/633	130/18639	0.0307692307692308	0.906015311702515	0.6482454786512	0.775954687662284
GO:0005249	voltage-gated potassium channel activity	3/633	98/18639	0.0306122448979592	0.901392784601992	0.651447926015914	0.777848269869748
GO:0008170	N-methyltransferase activity	3/633	98/18639	0.0306122448979592	0.901392784601992	0.651447926015914	0.777848269869748
GO:0160215	deacylase activity	2/633	65/18639	0.0307692307692308	0.906015311702515	0.652811971676528	0.778508686719834
GO:0005262	calcium channel activity	4/633	131/18639	0.0305343511450382	0.899099164284939	0.654176708052739	0.779168287506985
GO:0005310	dicarboxylic acid transmembrane transporter activity	1/633	31/18639	0.032258064516129	0.949854762268766	0.657664098404654	0.78138308721345
GO:0140457	protein demethylase activity	1/633	31/18639	0.032258064516129	0.949854762268766	0.657664098404654	0.78138308721345
GO:0016758	hexosyltransferase activity	6/633	197/18639	0.0304568527918782	0.896817186710612	0.663309874332512	0.787116785363673
GO:0016500	protein-hormone receptor activity	2/633	67/18639	0.0298507462686567	0.878970078517366	0.669107235710538	0.79032862388743
GO:0008378	galactosyltransferase activity	1/633	32/18639	0.03125	0.920171800947867	0.669309553354667	0.79032862388743
GO:0015106	bicarbonate transmembrane transporter activity	1/633	32/18639	0.03125	0.920171800947867	0.669309553354667	0.79032862388743
GO:0022884	macromolecule transmembrane transporter activity	1/633	32/18639	0.03125	0.920171800947867	0.669309553354667	0.79032862388743
GO:0016874	ligase activity	5/633	167/18639	0.029940119760479	0.881601725459035	0.673971967851293	0.794856374861476
GO:0005548	phospholipid transporter activity	2/633	68/18639	0.0294117647058824	0.866044047950934	0.677020209292621	0.7955194625715
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	2/633	68/18639	0.0294117647058824	0.866044047950934	0.677020209292621	0.7955194625715
GO:0140223	general transcription initiation factor activity	2/633	68/18639	0.0294117647058824	0.866044047950934	0.677020209292621	0.7955194625715
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	1/633	33/18639	0.0303030303030303	0.89228780697975	0.680559462137733	0.79578207509406
GO:0019956	chemokine binding	1/633	33/18639	0.0303030303030303	0.89228780697975	0.680559462137733	0.79578207509406
GO:0030296	protein tyrosine kinase activator activity	1/633	33/18639	0.0303030303030303	0.89228780697975	0.680559462137733	0.79578207509406
GO:0071889	14-3-3 protein binding	1/633	33/18639	0.0303030303030303	0.89228780697975	0.680559462137733	0.79578207509406
GO:0099094	ligand-gated monoatomic cation channel activity	4/633	136/18639	0.0294117647058824	0.866044047950934	0.682818663343261	0.797452453539575
GO:0030414	peptidase inhibitor activity	5/633	169/18639	0.029585798816568	0.871168568944726	0.684071048612998	0.797944358041893
GO:0005125	cytokine activity	7/633	234/18639	0.0299145299145299	0.880848219710779	0.685780454543223	0.798903696669
GO:0016757	glycosyltransferase activity	8/633	267/18639	0.0299625468164794	0.882262101283348	0.689803403605751	0.798903696669
GO:0008376	acetylgalactosaminyltransferase activity	1/633	34/18639	0.0294117647058824	0.866044047950934	0.691427239223985	0.798903696669
GO:0015020	glucuronosyltransferase activity	1/633	34/18639	0.0294117647058824	0.866044047950934	0.691427239223985	0.798903696669
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	1/633	34/18639	0.0294117647058824	0.866044047950934	0.691427239223985	0.798903696669
GO:0030332	cyclin binding	1/633	34/18639	0.0294117647058824	0.866044047950934	0.691427239223985	0.798903696669
GO:0052866	phosphatidylinositol phosphate phosphatase activity	1/633	34/18639	0.0294117647058824	0.866044047950934	0.691427239223985	0.798903696669
GO:0008028	monocarboxylic acid transmembrane transporter activity	2/633	70/18639	0.0285714285714286	0.841299932295193	0.6923832037798	0.798903696669
GO:0016782	transferase activity, transferring sulphur-containing groups	2/633	70/18639	0.0285714285714286	0.841299932295193	0.6923832037798	0.798903696669
GO:0140299	molecular sensor activity	2/633	71/18639	0.028169014084507	0.829450637474134	0.699836046073628	0.805076237814575
GO:0000175	3'-5'-RNA exonuclease activity	1/633	35/18639	0.0285714285714286	0.841299932295193	0.701925844844583	0.805076237814575
GO:0005343	organic acid:sodium symporter activity	1/633	35/18639	0.0285714285714286	0.841299932295193	0.701925844844583	0.805076237814575
GO:0034061	DNA polymerase activity	1/633	35/18639	0.0285714285714286	0.841299932295193	0.701925844844583	0.805076237814575
GO:0043015	gamma-tubulin binding	1/633	35/18639	0.0285714285714286	0.841299932295193	0.701925844844583	0.805076237814575
GO:0042379	chemokine receptor binding	2/633	72/18639	0.0277777777777778	0.817930489731438	0.707138467973004	0.810087027749503
GO:0016791	phosphatase activity	8/633	273/18639	0.0293040293040293	0.862871725430967	0.713068557952652	0.815906812436884
GO:0022843	voltage-gated monoatomic cation channel activity	4/633	143/18639	0.027972027972028	0.823650283365923	0.720052940598344	0.822471626502367
GO:1901681	sulfur compound binding	8/633	275/18639	0.0290909090909091	0.85659629470056	0.72056324232472	0.822471626502367
GO:0030551	cyclic nucleotide binding	1/633	37/18639	0.027027027027027	0.795824260279237	0.721865203046843	0.822471626502367
GO:0061659	ubiquitin-like protein ligase activity	11/633	372/18639	0.0295698924731183	0.870700198746369	0.722232897022391	0.822471626502367
GO:0008194	UDP-glycosyltransferase activity	4/633	145/18639	0.0275862068965517	0.812289589802255	0.730077549660402	0.829877719763144
GO:0000146	microfilament motor activity	1/633	38/18639	0.0263157894736842	0.774881516587678	0.731329740541271	0.829877719763144
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	1/633	38/18639	0.0263157894736842	0.774881516587678	0.731329740541271	0.829877719763144
GO:0098631	cell adhesion mediator activity	2/633	76/18639	0.0263157894736842	0.774881516587678	0.734876944894648	0.832918379101372
GO:0042393	histone binding	7/633	247/18639	0.0283400809716599	0.834487787094422	0.7380198702328	0.835494192716377
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	5/633	181/18639	0.0276243093922652	0.813411536749496	0.740176102064611	0.836948242617228
GO:0004532	RNA exonuclease activity	1/633	40/18639	0.025	0.736137440758294	0.749305004480463	0.842041311091756
GO:0015144	carbohydrate transmembrane transporter activity	1/633	40/18639	0.025	0.736137440758294	0.749305004480463	0.842041311091756
GO:0071949	FAD binding	1/633	40/18639	0.025	0.736137440758294	0.749305004480463	0.842041311091756
GO:0008237	metallopeptidase activity	5/633	184/18639	0.0271739130434783	0.80014939212858	0.752997881580803	0.842041311091756
GO:0061135	endopeptidase regulator activity	5/633	184/18639	0.0271739130434783	0.80014939212858	0.752997881580803	0.842041311091756
GO:0016835	carbon-oxygen lyase activity	2/633	79/18639	0.0253164556962025	0.74545563621093	0.754185696196335	0.842041311091756
GO:0033293	monocarboxylic acid binding	2/633	79/18639	0.0253164556962025	0.74545563621093	0.754185696196335	0.842041311091756
GO:0001530	lipopolysaccharide binding	1/633	41/18639	0.024390243902439	0.718182869032482	0.75783717998258	0.842041311091756
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	1/633	41/18639	0.024390243902439	0.718182869032482	0.75783717998258	0.842041311091756
GO:0008137	NADH dehydrogenase (ubiquinone) activity	1/633	41/18639	0.024390243902439	0.718182869032482	0.75783717998258	0.842041311091756
GO:0008227	G protein-coupled amine receptor activity	1/633	41/18639	0.024390243902439	0.718182869032482	0.75783717998258	0.842041311091756
GO:0016877	ligase activity, forming carbon-sulfur bonds	1/633	41/18639	0.024390243902439	0.718182869032482	0.75783717998258	0.842041311091756
GO:0042287	MHC protein binding	1/633	41/18639	0.024390243902439	0.718182869032482	0.75783717998258	0.842041311091756
GO:0140318	protein transporter activity	1/633	41/18639	0.024390243902439	0.718182869032482	0.75783717998258	0.842041311091756
GO:0140828	metal cation:monoatomic cation antiporter activity	1/633	41/18639	0.024390243902439	0.718182869032482	0.75783717998258	0.842041311091756
GO:0061630	ubiquitin protein ligase activity	10/633	353/18639	0.028328611898017	0.834150074513647	0.763599178784606	0.845654582760205
GO:1990782	protein tyrosine kinase binding	3/633	117/18639	0.0256410256410256	0.755012759752096	0.763941597684145	0.845654582760205
GO:0008234	cysteine-type peptidase activity	5/633	187/18639	0.0267379679144385	0.787312770864485	0.765342549253821	0.845654582760205
GO:0008307	structural constituent of muscle	1/633	42/18639	0.0238095238095238	0.701083276912661	0.766079413828748	0.845654582760205
GO:0031492	nucleosomal DNA binding	1/633	42/18639	0.0238095238095238	0.701083276912661	0.766079413828748	0.845654582760205
GO:0030971	receptor tyrosine kinase binding	2/633	81/18639	0.0246913580246914	0.727049324205722	0.766374465626436	0.845654582760205
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/633	43/18639	0.0232558139534884	0.684779014658878	0.774041543798442	0.853134192935137
GO:0001223	transcription coactivator binding	1/633	44/18639	0.0227272727272727	0.669215855234813	0.781733074384352	0.859637745027466
GO:0003954	NADH dehydrogenase activity	1/633	44/18639	0.0227272727272727	0.669215855234813	0.781733074384352	0.859637745027466
GO:0004527	exonuclease activity	2/633	84/18639	0.0238095238095238	0.701083276912661	0.783671500708918	0.860783341739773
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	3/633	122/18639	0.0245901639344262	0.724069613860617	0.788117906918872	0.864677932162419
GO:0140303	intramembrane lipid transporter activity	1/633	45/18639	0.0222222222222222	0.65434439178515	0.78916318806624	0.864836370483551
GO:0008236	serine-type peptidase activity	5/633	194/18639	0.0257731958762887	0.758904578101334	0.792320807922092	0.867306699663864
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	6/633	229/18639	0.0262008733624454	0.771497754506509	0.793931634710124	0.868080147291252
GO:0004866	endopeptidase inhibitor activity	4/633	161/18639	0.0248447204968944	0.731565158517559	0.800721088371907	0.874507673307202
GO:0008083	growth factor activity	4/633	162/18639	0.0246913580246914	0.727049324205722	0.804592381991677	0.877161721986368
GO:0016651	oxidoreductase activity, acting on NAD(P)H	2/633	88/18639	0.0227272727272727	0.669215855234813	0.804978621947906	0.877161721986368
GO:0017171	serine hydrolase activity	5/633	198/18639	0.0252525252525253	0.743573172483125	0.806615254188901	0.877948575987919
GO:0015103	inorganic anion transmembrane transporter activity	4/633	165/18639	0.0242424242424242	0.7138302455838	0.815840996461146	0.88698454881393
GO:0035591	signaling adaptor activity	3/633	129/18639	0.0232558139534884	0.684779014658878	0.818479945978708	0.888847000157873
GO:0005261	monoatomic cation channel activity	9/633	341/18639	0.0263929618768328	0.777153896401718	0.822620611758676	0.889240174095142
GO:0015605	organophosphate ester transmembrane transporter activity	1/633	50/18639	0.02	0.588909952606635	0.822692690868598	0.889240174095142
GO:0048020	CCR chemokine receptor binding	1/633	50/18639	0.02	0.588909952606635	0.822692690868598	0.889240174095142
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	4/633	167/18639	0.0239520958083832	0.705281380367228	0.823041090828227	0.889240174095142
GO:0043178	alcohol binding	2/633	92/18639	0.0217391304347826	0.640119513702864	0.824399744734038	0.889240174095142
GO:0052689	carboxylic ester hydrolase activity	2/633	92/18639	0.0217391304347826	0.640119513702864	0.824399744734038	0.889240174095142
GO:0008168	methyltransferase activity	5/633	204/18639	0.0245098039215686	0.721703373292445	0.826580341849877	0.890591614114346
GO:0051213	dioxygenase activity	2/633	93/18639	0.021505376344086	0.633236508179178	0.828975728507746	0.892171187631655
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	3/633	132/18639	0.0227272727272727	0.669215855234813	0.830316238351536	0.892613201363353
GO:0030159	signaling receptor complex adaptor activity	1/633	52/18639	0.0192307692307692	0.566259569814072	0.834562882764274	0.896174907666335
GO:0016251	RNA polymerase II general transcription initiation factor activity	1/633	53/18639	0.0188679245283019	0.555575426987392	0.840197019268832	0.896879140113352
GO:0017046	peptide hormone binding	1/633	53/18639	0.0188679245283019	0.555575426987392	0.840197019268832	0.896879140113352
GO:1901505	carbohydrate derivative transmembrane transporter activity	1/633	53/18639	0.0188679245283019	0.555575426987392	0.840197019268832	0.896879140113352
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	1/633	53/18639	0.0188679245283019	0.555575426987392	0.840197019268832	0.896879140113352
GO:0015297	antiporter activity	3/633	135/18639	0.0222222222222222	0.65434439178515	0.841484531498421	0.896879140113352
GO:0004896	cytokine receptor activity	2/633	96/18639	0.0208333333333333	0.613447867298578	0.842065878603308	0.896879140113352
GO:0005244	voltage-gated monoatomic ion channel activity	4/633	173/18639	0.023121387283237	0.680820754458538	0.843256277819501	0.896879140113352
GO:0140030	modification-dependent protein binding	4/633	173/18639	0.023121387283237	0.680820754458538	0.843256277819501	0.896879140113352
GO:0016779	nucleotidyltransferase activity	3/633	136/18639	0.0220588235294118	0.6495330359632	0.845063460855305	0.896879140113352
GO:0015485	cholesterol binding	1/633	54/18639	0.0185185185185185	0.545286993154292	0.845639572093691	0.896879140113352
GO:0030594	neurotransmitter receptor activity	2/633	97/18639	0.0206185567010309	0.607123662481067	0.846223348950156	0.896879140113352
GO:0003823	antigen binding	4/633	174/18639	0.0229885057471264	0.676907991501879	0.846429688481976	0.896879140113352
GO:0022832	voltage-gated channel activity	4/633	175/18639	0.0228571428571429	0.673039945836154	0.849548776039187	0.898637144194731
GO:0008374	O-acyltransferase activity	1/633	55/18639	0.0181818181818182	0.53537268418785	0.850897045909386	0.898637144194731
GO:0098632	cell-cell adhesion mediator activity	1/633	55/18639	0.0181818181818182	0.53537268418785	0.850897045909386	0.898637144194731
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	1/633	56/18639	0.0178571428571429	0.525812457684496	0.855975724877281	0.903007358112296
GO:0016741	transferase activity, transferring one-carbon groups	5/633	215/18639	0.0232558139534884	0.684779014658878	0.858825167627883	0.905018837456386
GO:0015932	nucleobase-containing compound transmembrane transporter activity	1/633	57/18639	0.0175438596491228	0.516587677725118	0.860881680113394	0.906191242224625
GO:0020037	heme binding	3/633	142/18639	0.0211267605633803	0.6220879781056	0.865096538667726	0.909630533538902
GO:0005253	monoatomic anion channel activity	2/633	103/18639	0.0194174757281553	0.571757235540422	0.869143491196785	0.912885942613691
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	1/633	60/18639	0.0166666666666667	0.490758293838863	0.874620868656216	0.916633224792541
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/633	60/18639	0.0166666666666667	0.490758293838863	0.874620868656216	0.916633224792541
GO:0004497	monooxygenase activity	2/633	106/18639	0.0188679245283019	0.555575426987392	0.879387558860948	0.920623834794449
GO:0015276	ligand-gated monoatomic ion channel activity	4/633	186/18639	0.021505376344086	0.633236508179178	0.880451860587572	0.920733971856285
GO:0022834	ligand-gated channel activity	4/633	188/18639	0.0212765957446809	0.626499949581527	0.885437817545366	0.921563760055502
GO:0008509	monoatomic anion transmembrane transporter activity	3/633	149/18639	0.0201342281879195	0.592862368395941	0.885558645045035	0.921563760055502
GO:0005496	steroid binding	2/633	108/18639	0.0185185185185185	0.545286993154292	0.885800249496032	0.921563760055502
GO:0022824	transmitter-gated monoatomic ion channel activity	1/633	63/18639	0.0158730158730159	0.467388851275107	0.887005119053421	0.921563760055502
GO:0022835	transmitter-gated channel activity	1/633	63/18639	0.0158730158730159	0.467388851275107	0.887005119053421	0.921563760055502
GO:1901682	sulfur compound transmembrane transporter activity	1/633	63/18639	0.0158730158730159	0.467388851275107	0.887005119053421	0.921563760055502
GO:0046906	tetrapyrrole binding	3/633	152/18639	0.0197368421052632	0.581161137440758	0.89344739900239	0.92725351680248
GO:0042054	histone methyltransferase activity	1/633	67/18639	0.0149253731343284	0.439485039258683	0.901638478378934	0.933735641039673
GO:0050840	extracellular matrix binding	1/633	67/18639	0.0149253731343284	0.439485039258683	0.901638478378934	0.933735641039673
GO:0032934	sterol binding	1/633	68/18639	0.0147058823529412	0.433022023975467	0.904990989857834	0.936197575715001
GO:0016279	protein-lysine N-methyltransferase activity	1/633	69/18639	0.0144927536231884	0.426746342468576	0.908229410159379	0.936712903418783
GO:0098960	postsynaptic neurotransmitter receptor activity	1/633	69/18639	0.0144927536231884	0.426746342468576	0.908229410159379	0.936712903418783
GO:0009055	electron transfer activity	2/633	116/18639	0.0172413793103448	0.50768099362641	0.908416367794673	0.936712903418783
GO:0016278	lysine N-methyltransferase activity	1/633	70/18639	0.0142857142857143	0.420649966147596	0.911357616048939	0.938737458591181
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	1/633	73/18639	0.0136986301369863	0.403362981237421	0.920117768547199	0.945493774819019
GO:0015108	chloride transmembrane transporter activity	2/633	121/18639	0.0165289256198347	0.486702440170773	0.92034736163598	0.945493774819019
GO:0031267	small GTPase binding	6/633	283/18639	0.0212014134275618	0.624286168840956	0.921862943609464	0.945493774819019
GO:0031491	nucleosome binding	1/633	74/18639	0.0135135135135135	0.397912130139618	0.922841319797313	0.945493774819019
GO:0035064	methylated histone binding	1/633	74/18639	0.0135135135135135	0.397912130139618	0.922841319797313	0.945493774819019
GO:0140034	methylation-dependent protein binding	1/633	76/18639	0.0131578947368421	0.387440758293839	0.928013423869319	0.949779197137043
GO:0051540	metal cluster binding	1/633	77/18639	0.012987012987013	0.382409060134179	0.930468172707907	0.951277365068787
GO:0000049	tRNA binding	1/633	80/18639	0.0125	0.368068720379147	0.937342211701918	0.957285663014725
GO:0005216	monoatomic ion channel activity	10/633	448/18639	0.0223214285714286	0.65726557210562	0.942115430762929	0.960547330215094
GO:0005254	chloride channel activity	1/633	83/18639	0.0120481927710843	0.354765031690744	0.943537637909202	0.960547330215094
GO:0030165	PDZ domain binding	1/633	83/18639	0.0120481927710843	0.354765031690744	0.943537637909202	0.960547330215094
GO:0050660	flavin adenine dinucleotide binding	1/633	86/18639	0.0116279069767442	0.342389507329439	0.949121349264071	0.96520815179397
GO:0004197	cysteine-type endopeptidase activity	1/633	88/18639	0.0113636363636364	0.334607927617406	0.952534016906191	0.967251860567841
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	1/633	89/18639	0.0112359550561798	0.330848287981256	0.954153658289318	0.967251860567841
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	1/633	89/18639	0.0112359550561798	0.330848287981256	0.954153658289318	0.967251860567841
GO:0140793	histone H2AXY142 phosphatase activity	1/633	90/18639	0.0111111111111111	0.327172195892575	0.955718118359553	0.967815816060307
GO:0004867	serine-type endopeptidase inhibitor activity	1/633	95/18639	0.0105263157894737	0.309952606635071	0.962776212875351	0.973935895005624
GO:0004725	protein tyrosine phosphatase activity	1/633	98/18639	0.0102040816326531	0.300464261533997	0.9664596709932	0.976632930687865
GO:0140375	immune receptor activity	2/633	156/18639	0.0128205128205128	0.377506379876048	0.970876998034191	0.980065108425682
GO:0005516	calmodulin binding	3/633	207/18639	0.0144927536231884	0.426746342468576	0.973464387999084	0.981644761007479
GO:0004222	metalloendopeptidase activity	1/633	110/18639	0.00909090909090909	0.267686342093925	0.977895543964148	0.985078407351083
GO:0045182	translation regulator activity	6/633	356/18639	0.0168539325842697	0.496272431971883	0.982988009709486	0.988656705847809
GO:0004252	serine-type endopeptidase activity	2/633	176/18639	0.0113636363636364	0.334607927617406	0.983909169509595	0.988656705847809
GO:0022836	gated channel activity	5/633	318/18639	0.0157232704402516	0.462979522489493	0.984668901385333	0.988656705847809
GO:0004175	endopeptidase activity	7/633	405/18639	0.0172839506172839	0.508934526944006	0.985567153642035	0.988656705847809
GO:0005179	hormone activity	1/633	132/18639	0.00757575757575758	0.223071951744938	0.989715671371863	0.991781883629424
GO:0140101	catalytic activity, acting on a tRNA	1/633	139/18639	0.00719424460431655	0.21183811244843	0.991939562963595	0.992973910787332
GO:0030371	translation repressor activity	3/633	329/18639	0.00911854103343465	0.268499978392083	0.99914590010862	0.99914590010862