category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	45/223	238/9376	7.94965519840223	C7/RPL14/RPL9/RPL8/RPL39/RPL18/RPS3/RPL7A/RPS7/RPS3A/RPS24/IL6ST/RPL11/RPL5/RPL19/RPS4X/RPS6/RPL15/RPL24/RPS28/RPL7/RPL13/RPL10/RPS2/RPL3/RPS27/RPL18A/RPS5/CFD/RSL24D1/RPL36AL/RPS23/RPS25/RPS13/RPS27L/RPSA/RPS15A/RPS9/RPL36/RPL12/AGTR1/RPL10A/RPL13A/RPS14/RPL29	16.9504994053757
Genetic Information Processing	Translation	hsa03010	Ribosome	43/223	222/9376	8.14382095099584	RPL14/RPL9/RPL8/RPL39/RPL18/RPS3/RPL7A/RPS7/RPS3A/RPS24/RPL11/RPL5/RPL19/RPS4X/RPS6/RPL15/RPL24/RPS28/RPL7/RPL13/RPL10/RPS2/RPL3/RPS27/RPL18A/RACK1/RPS5/RSL24D1/RPL36AL/RPS23/RPS25/MRPS6/RPS13/RPS27L/RPSA/RPS15A/RPS9/RPL36/RPL12/RPL10A/RPL13A/RPS14/RPL29	16.8134924347471
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	8/223	42/9376	8.00854153320521	FTL/FTH1/SLC40A1/SLC3A2/PCBP1/GPX4/PCBP2/VDAC2	7.10517430922508
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	16/223	250/9376	2.69086995515695	CTSL/NPC2/NEU1/ATP6V0C/ATP6V0E1/VAMP8/ACP5/LAPTM4A/PSAP/CTSD/TPP1/CLTC/VPS26A/ATP6V1B2/ABCA5/CD164	4.22957098317662
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	7/223	95/9376	3.09804106679254	CTSL/IL18/ATP6V0C/ATP6V0E1/ACP5/CCL3/ATP6V1B2	3.20800280698666
Organismal Systems	Excretory system	hsa04966	Collecting duct acid secretion	3/223	28/9376	4.50480461242793	ATP6V0C/ATP6V0E1/ATP6V1B2	2.89894392032693
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	4/223	51/9376	3.29763474896685	ATP6V0C/ATP6V0E1/ATP6V1B2/KDELR1	2.56801760760595
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	6/223	101/9376	2.49771344847489	VEGFC/MMP2/AGT/AGTR1/PLCB1/JAK2	2.36204841856474
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	9/223	187/9376	2.02354859595693	TXNIP/IL18/GABARAP/IFI16/GABARAPL1/ANTXR2/HSP90AB1/PLCB1/VDAC2	2.206741604172
NA	NA	hsa04081	Hormone signaling	10/223	219/9376	1.91985584700125	GNGT1/VIPR2/SLC40A1/THRB/RAMP1/PRLR/AGT/AGTR1/PLCB1/JAK2	2.14991634816699
Cellular Processes	Transport and catabolism	hsa04136	Autophagy - other	3/223	32/9376	3.94170403587444	GABARAP/GABARAPL1/IGBP1	2.60173997097808
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	5/223	80/9376	2.62780269058296	RPS6/PDGFRA/PDGFD/MET/JAK2	2.28220701785421
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	4/223	56/9376	3.00320307495195	IL18/EEF1A1/EEF1G/SAR1A	2.34675295853123
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	5/223	83/9376	2.53282187044141	IL18/PCBP1/IFI16/CCL4/POLR1D	2.1893192943254
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	9/223	204/9376	1.85491954629385	CTSL/RPS6/DCN/EIF4B/MMP2/MET/TWIST1/PPP1CB/LUM	1.92692426573105
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	9/223	205/9376	1.84587115826315	PDK4/COX7A2L/MMP2/AGT/AGTR1/PLCB1/PPP1CB/CTSD/VDAC2	1.91130123043239
Organismal Systems	Digestive system	hsa04978	Mineral absorption	4/223	61/9376	2.75703888848048	FTL/FTH1/SLC40A1/CYBRD1	2.14887523221026
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	3/223	37/9376	3.40904132832384	IL18/PLCB1/HBA2	2.29166569414303
Metabolism	Energy metabolism	hsa00910	Nitrogen metabolism	2/223	17/9376	4.94645212345028	CA8/GLUL	2.54198459384157
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	5/223	89/9376	2.36206983423187	GNGT1/GABARAP/GABARAPL1/TRAK2/GLUL	2.01517605370137
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	4/223	63/9376	2.66951384440174	PTGES3/PTGDS/GPX4/PTGES	2.07525675692085
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	7/223	157/9376	1.87461083659421	HLA-A/IGFBP3/GADD45G/HIPK3/PPP1CB/SQSTM1/VDAC2	1.72496032806387
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	10/223	254/9376	1.65530878146958	VEGFC/EDNRB/PDGFRA/PDE1C/PDGFD/MET/AGTR1/PLCB1/TNNC1/VDAC2	1.65262436232137
Organismal Systems	Endocrine system	hsa04924	Renin secretion	4/223	69/9376	2.43738220575811	PDE1C/AGT/AGTR1/PLCB1	1.87045942250154
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	4/223	71/9376	2.36872355207478	ATP6V0C/ATP6V0E1/MET/ATP6V1B2	1.80693722327274
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	5/223	100/9376	2.10224215246637	IL18/IL6ST/CCL4/XCL1/CCL3	1.72962910255034
Human Diseases	Cancer: specific types	hsa05218	Melanoma	4/223	73/9376	2.3038270164015	GADD45G/PDGFRA/PDGFD/MET	1.7455256453449
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	3/223	46/9376	2.74205498147787	FTL/FTH1/BLVRB	1.84865679011672
Organismal Systems	Endocrine system	hsa04614	Renin-angiotensin system	2/223	23/9376	3.65607330863716	AGT/AGTR1	1.99060388316921
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	4/223	75/9376	2.24239162929746	IGFBP3/GADD45G/SESN1/CCNG2	1.68608965851533
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	5/223	105/9376	2.0021353833013	GABARAP/GABARAPL1/TOMM20/SQSTM1/CCZ1B	1.61181092068288
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	7/223	168/9376	1.75186846038864	FTL/FTH1/HSP90AB1/SQSTM1/GLUL/VDAC2/JAK2	1.53486503014548
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	7/223	169/9376	1.74150237482421	CTSL/GABARAP/GABARAPL1/VAMP8/SQSTM1/IGBP1/CTSD	1.51828452509336
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	3/223	50/9376	2.52269058295964	IL18/MET/HBA2	1.68502091956028
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	4/223	79/9376	2.12885281262417	ATP6V0C/ATP6V0E1/CLTC/ATP6V1B2	1.57266343032258
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	4/223	82/9376	2.05096795362572	HLA-A/CTSL/B2M/HSP90AB1	1.49194015946415
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	5/223	116/9376	1.81227771764342	GNGT1/DLGAP1/PLCB1/GRIK1/GLUL	1.373992555547
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	6/223	149/9376	1.69308092816083	PDGFRA/PDGFD/AGT/AGTR1/PLCB1/KIT	1.33107694343394
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	4/223	86/9376	1.95557409531755	GJA1/TCF7L2/SGCA/CACNB2	1.38951127485295
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	4/223	88/9376	1.91112922951488	C7/CLU/CFD/SERPING1	1.34034485160349
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	6/223	154/9376	1.63811076815561	AGT/AGTR1/PLCB1/PPP1CB/TNNC1/CACNB2	1.24623577298859
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	4/223	89/9376	1.8896558673855	GJA1/PDGFRA/PDGFD/PLCB1	1.31624176303796
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	6/223	155/9376	1.62754231158687	HLA-A/CTSL/ATP6V0C/ATP6V0E1/COLEC12/ATP6V1B2	1.22963492479902
Metabolism	Carbohydrate metabolism	hsa00630	Glyoxylate and dicarboxylate metabolism	2/223	31/9376	2.71257051931144	ACSS1/GLUL	1.49071971900096
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	8/223	227/9376	1.48175658323621	GNGT1/HLA-A/PDGFRA/B2M/CCL4/PLCB1/CCL3/IL1R1	1.14685922262974
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	6/223	158/9376	1.59663960946813	RPS6/SLC3A2/EIF4B/FNIP1/LPIN1/ATP6V1B2	1.18053430545425
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	10/223	300/9376	1.40149476831091	VEGFC/GADD45G/PDGFRA/PDGFD/MKNK2/MET/DDIT3/KIT/IL1R1/CACNB2	1.10318821270101
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	5/223	130/9376	1.61710934805105	GNGT1/VEGFC/EDNRB/MMP2/PLCB1	1.10589321963571
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	3/223	65/9376	1.94053121766126	AGT/AGTR1/PLCB1	1.18764889376622
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	4/223	99/9376	1.69878153734656	AGT/TNNC1/SGCA/CACNB2	1.09096691294168
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	5/223	133/9376	1.58063319734313	GABARAP/DEPP1/GADD45G/GABARAPL1/CCNG2	1.05263436755205
Metabolism	Glycan biosynthesis and metabolism	hsa00512	Mucin type O-glycan biosynthesis	2/223	36/9376	2.33582461385152	GALNT15/GALNT1	1.25338240076412
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	5/223	134/9376	1.56883742721371	RAMP1/AGT/AGTR1/PLCB1/PPP1CB	1.03517534348634
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	4/223	101/9376	1.66514229898326	TCF7L2/EDNRB/PLCB1/KIT	1.0489979355088
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	2/223	37/9376	2.27269421888256	TCF7L2/GADD45G	1.21068478413221
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	6/223	174/9376	1.44982217411474	HSP90AB1/CRYAB/SKP1/DDIT3/UBE2D3/SAR1A	0.93482584016658
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	3/223	71/9376	1.77654266405609	PRLR/CISH/JAK2	1.02516234415294
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	3/223	71/9376	1.77654266405609	PDGFRA/MET/KIT	1.02516234415294
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	4/223	105/9376	1.60170830664104	AGT/TNNC1/SGCA/CACNB2	0.967773452439853
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	11/223	362/9376	1.27760572801823	GNGT1/RPS6/VEGFC/EIF4B/PDGFRA/HSP90AB1/PRLR/PDGFD/MET/KIT/JAK2	0.840775929647243
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	8/223	250/9376	1.34543497757848	HLA-A/PDGFRA/SNX2/BIN1/CLTC/VPS26A/NEDD4L/TSG101	0.864076952390209
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	4/223	106/9376	1.58659785091801	TCF7L2/PDGFRA/HSP90AB1/PDGFD	0.948003349186038
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	5/223	142/9376	1.48045222004674	CTSL/HSP90AB1/MMP2/SQSTM1/IL1R1	0.900442075026914
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	3/223	73/9376	1.72787026230112	BST2/SERINC3/TSG101	0.974451513389482
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	6/223	180/9376	1.40149476831091	HLA-A/BST2/B2M/PPP1CB/JAK2/SRSF7	0.848932187638155
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	4/223	109/9376	1.5429300201588	IL6ST/HSP90AB1/IL1R1/JAK2	0.889905440175635
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	3/223	75/9376	1.68179372197309	GPX3/SLC26A4/PLCB1	0.925284199242039
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	4/223	110/9376	1.5289033836119	DCN/SKP1/IGSF1/BMP5	0.870929254169328
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	11/223	370/9376	1.24998182038541	VIPR2/THRB/SPX/EDNRB/NPW/PRLR/PTH2R/AGT/AGTR1/GRIK1/NMUR1	0.765772305008322
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	9/223	298/9376	1.26981069612062	IL18/IL6ST/PRLR/CCL4/XCL1/BMP5/CCL3/IL1R1/GDF15	0.738802818891
Metabolism	Glycan biosynthesis and metabolism	hsa00604	Glycosphingolipid biosynthesis - ganglio series	1/223	15/9376	2.80298953662182	ST3GAL5	1.09077217756092
Metabolism	Carbohydrate metabolism	hsa00620	Pyruvate metabolism	2/223	47/9376	1.78914225741819	ACSS1/ADH1B	0.84653130056138
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	6/223	193/9376	1.30709356630033	GNGT1/CCL4/XCL1/PLCB1/CCL3/JAK2	0.672842504687906
Genetic Information Processing	Chromosome	hsa03083	Polycomb repressive complex	3/223	83/9376	1.51969312226484	SKP1/UBE2D3/PHF1	0.742274233975398
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	5/223	158/9376	1.33053300789011	GADD45G/STAG2/CDKN1C/SKP1/SMC3	0.654005447689097
Metabolism	Glycan biosynthesis and metabolism	hsa00514	Other types of O-glycan biosynthesis	2/223	49/9376	1.71611604282969	GALNT15/GALNT1	0.784452756318679
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	3/223	87/9376	1.44982217411474	COX7A2L/TNNC1/CACNB2	0.657918871493531
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	6/223	201/9376	1.25506994177097	NUPR1/IGFBP3/GADD45G/MAF/MET/DDIT3	0.570572208035063
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	2/223	52/9376	1.61710934805105	NPC2/VDAC2	0.696496603887656
Metabolism	Glycan biosynthesis and metabolism	hsa00511	Other glycan degradation	1/223	18/9376	2.33582461385152	NEU1	0.885422414906941
Organismal Systems	Digestive system	hsa04980	Cobalamin transport and metabolism	1/223	18/9376	2.33582461385152	PRDX1	0.885422414906941
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	2/223	53/9376	1.58659785091801	PLCB1/CLTC	0.66843148590794
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	5/223	166/9376	1.2664109352207	EDNRB/AGTR1/PLCB1/PPP1CB/VDAC2	0.540545946009846
Human Diseases	Substance dependence	hsa05032	Morphine addiction	3/223	91/9376	1.3860937269009	GNGT1/PDE1C/PDE4B	0.577668685944345
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	5/223	168/9376	1.25133461456331	IL6ST/PDGFRA/PRLR/CISH/JAK2	0.513074734587113
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	2/223	55/9376	1.5289033836119	NEU1/PSAP	0.614020363892115
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	3/223	93/9376	1.35628525965572	TCF7L2/ARHGAP29/MET	0.538953743162713
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	3/223	93/9376	1.35628525965572	MAF/RBPJ/JAK2	0.538953743162713
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	6/223	212/9376	1.18994838818851	VEGFC/PDGFRA/PDGFD/MET/PLCB1/KIT	0.436633789797502
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	7/223	253/9376	1.16329605274819	IL18/SKP1/TIFA/PLCB1/SQSTM1/UBE2D3/IL1R1	0.410982612624482
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	6/223	214/9376	1.17882737521479	GNGT1/HLA-A/BST2/CFL2/B2M/SKP1	0.413049483681278
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	6/223	216/9376	1.16791230692576	IL18/HSP90AB1/DDIT3/PLCB1/CCL3/JAK2	0.389688873311352
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	2/223	59/9376	1.42524891692635	GPX3/GPX4	0.511431546267638
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	2/223	59/9376	1.42524891692635	TCF7L2/GADD45G	0.511431546267638
Metabolism	Amino acid metabolism	hsa00340	Histidine metabolism	1/223	22/9376	1.91112922951488	AOC1	0.667803937530684
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	4/223	137/9376	1.22758665837452	CTSL/GADD45G/DDIT3/CTSD	0.418842687666921
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	3/223	98/9376	1.28708703212227	AGT/AGTR1/PLCB1	0.445918784871818
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	4/223	138/9376	1.21869110287905	ATP6V0C/ATP6V0E1/COX7A2L/ATP6V1B2	0.403959678199748
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	4/223	138/9376	1.21869110287905	SKP1/PPP1CB/SMC3/SPDYE2	0.403959678199748
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	5/223	178/9376	1.18103491711594	RSPO2/FRZB/TCF7L2/SKP1/PLCB1	0.380611568739059
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	3/223	99/9376	1.27408615300992	PLCB1/PPP1CB/IL1R1	0.427914746237772
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	4/223	139/9376	1.20992354098784	HSP90AB1/MMP2/PLCB1/CTSD	0.389187972465994
Metabolism	Amino acid metabolism	hsa00220	Arginine biosynthesis	1/223	23/9376	1.82803665431858	GLUL	0.620575107672291
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	4/223	140/9376	1.20128122998078	GNGT1/RPS6/AGTR1/PLCB1	0.374525740964444
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	4/223	142/9376	1.18436177603739	UBE2B/SKP1/UBE2D3/NEDD4L	0.345522599842719
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	2/223	63/9376	1.33475692220087	TCF7L2/GADD45G	0.416113090078821
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	3/223	103/9376	1.22460707910662	SAP18/PPP1CB/PABPC1	0.35775709971656
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	3/223	103/9376	1.22460707910662	PRDX1/PLCB1/IL1R1	0.35775709971656
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	3/223	105/9376	1.20128122998078	GADD45G/CCL4/IL1R1	0.323735984196822
Organismal Systems	Digestive system	hsa04977	Vitamin digestion and absorption	1/223	26/9376	1.61710934805105	SLC19A3	0.491812239142891
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	2/223	66/9376	1.27408615300992	IL18/MAF	0.348771156238246
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	2/223	67/9376	1.25506994177097	ACSS1/ADH1B	0.327040477159505
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	2/223	67/9376	1.25506994177097	PLCB1/PPP1CB	0.327040477159505
Metabolism	Lipid metabolism	hsa01040	Biosynthesis of unsaturated fatty acids	1/223	27/9376	1.55721640923435	ELOVL2	0.452563514142973
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	6/223	233/9376	1.08269982101272	TMOD1/DCN/FMNL2/SYNE2/TNNC1/SGCA	0.199523708703689
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	3/223	109/9376	1.1571975151191	OGA/AGT/PPP1CB	0.257659217012283
Metabolism	Metabolism of cofactors and vitamins	hsa00830	Retinol metabolism	2/223	68/9376	1.23661303086257	CYP2W1/ADH1B	0.305647794402042
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	2/223	68/9376	1.23661303086257	TCF7L2/KIT	0.305647794402042
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	3/223	110/9376	1.14667753770893	RPS6/MKNK2/EGLN3	0.241529478688241
Metabolism	Lipid metabolism	hsa00062	Fatty acid elongation	1/223	28/9376	1.50160153747598	ELOVL2	0.414891809471026
Metabolism	Metabolism of cofactors and vitamins	hsa00790	Folate biosynthesis	1/223	28/9376	1.50160153747598	DHFR	0.414891809471026
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	2/223	70/9376	1.20128122998078	MET/EGLN3	0.263831782766865
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	2/223	70/9376	1.20128122998078	HLA-A/SGCA	0.263831782766865
NA	NA	hsa04518	Integrin signaling	4/223	154/9376	1.09207384543707	VEGFC/PDGFRA/PDGFD/MET	0.179821005484619
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	5/223	196/9376	1.07257252676856	GNGT1/HLA-A/IL6ST/TCF7L2/JAK2	0.160263741627693
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	6/223	238/9376	1.05995402645363	GNGT1/VEGFC/PDGFRA/PDGFD/MET/KIT	0.14623037557112
Organismal Systems	Sensory system	hsa04744	Phototransduction	1/223	29/9376	1.44982217411474	GNGT1	0.378669282231136
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	4/223	155/9376	1.08502820772458	TCF7L2/AGT/AGTR1/PLCB1	0.166608134432913
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	1/223	30/9376	1.40149476831091	DHFR	0.34378266042089
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	3/223	115/9376	1.09682199259115	GNGT1/PLCB1/JAK2	0.16306108687771
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	3/223	115/9376	1.09682199259115	NACA/PLCB1/PDE4B	0.16306108687771
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	2/223	73/9376	1.15191350820075	GADD45G/MET	0.203377381434061
Genetic Information Processing	Folding, sorting and degradation	hsa03060	Protein export	1/223	31/9376	1.35628525965572	IMMP2L	0.310131148568238
NA	NA	hsa04981	Folate transport and metabolism	1/223	31/9376	1.35628525965572	DHFR	0.310131148568238
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	5/223	203/9376	1.03558726722481	VEGFC/PDGFRA/PDGFD/MET/PPP1CB	0.0800098212593171
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	1/223	32/9376	1.31390134529148	ACSS1	0.2776246920251
Human Diseases	Immune disease	hsa05310	Asthma	1/223	32/9376	1.31390134529148	PRG2	0.2776246920251
Human Diseases	Cancer: specific types	hsa05214	Glioma	2/223	76/9376	1.10644323814019	GADD45G/PDGFRA	0.145425222949915
Genetic Information Processing	Folding, sorting and degradation	hsa04130	SNARE interactions in vesicular transport	1/223	33/9376	1.27408615300992	VAMP8	0.246182529296184
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	2/223	78/9376	1.0780728987007	MET/CLTC	0.108071000766606
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	2/223	78/9376	1.0780728987007	CFL2/SERPING1	0.108071000766606
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	2/223	78/9376	1.0780728987007	EEF1A1/JAK2	0.108071000766606
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	3/223	122/9376	1.03388958318018	IGFBP3/PLCB1/JAK2	0.0588081792684459
Genetic Information Processing	Transcription	hsa03020	RNA polymerase	1/223	34/9376	1.23661303086257	POLR1D	0.21573197738509
Organismal Systems	Environmental adaptation	hsa04710	Circadian rhythm	1/223	34/9376	1.23661303086257	SKP1	0.21573197738509
Organismal Systems	Immune system	hsa04611	Platelet activation	3/223	126/9376	1.00106769165065	VAMP8/PLCB1/PPP1CB	0.00188328735875576
Metabolism	Amino acid metabolism	hsa00250	Alanine, aspartate and glutamate metabolism	1/223	37/9376	1.13634710944128	GLUL	0.129703874121392
Metabolism	Amino acid metabolism	hsa00350	Tyrosine metabolism	1/223	37/9376	1.13634710944128	ADH1B	0.129703874121392
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	1/223	38/9376	1.10644323814019	NAPRT	0.102621717760209
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	1/223	38/9376	1.10644323814019	NEDD4L	0.102621717760209
Metabolism	Metabolism of cofactors and vitamins	hsa00670	One carbon pool by folate	1/223	39/9376	1.0780728987007	DHFR	0.0762579746986756
Human Diseases	Immune disease	hsa05330	Allograft rejection	1/223	39/9376	1.0780728987007	HLA-A	0.0762579746986756
Organismal Systems	Sensory system	hsa04742	Taste transduction	2/223	86/9376	0.977787047658776	PDE1C/PLCB1	-0.0323001093030315
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	2/223	87/9376	0.966548116076491	TCF7L2/GADD45G	-0.0489273917267449
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	3/223	133/9376	0.94837991840588	GNGT1/PLCB1/PPP1CB	-0.093582441015167
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	1/223	41/9376	1.02548397681286	MMP2	0.0255245625091776
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	4/223	181/9376	0.92916780219508	IL18/ATP6V0C/CTSD/JAK2	-0.150193271313757
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	1/223	42/9376	1.00106769165065	AOC1	0.00108241283160551
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	3/223	138/9376	0.91401832715929	RPS6/MKNK2/PPP1CB	-0.158822779868727
Metabolism	Lipid metabolism	hsa00071	Fatty acid degradation	1/223	43/9376	0.977787047658776	ADH1B	-0.0227869509886063
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	5/223	232/9376	0.90613885882171	C7/PDGFRA/CFL2/PDGFD/PPP1CB	-0.225952969068159
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	2/223	93/9376	0.904190173103814	MMP2/PLCB1	-0.144931802363555
Genetic Information Processing	Replication and repair	hsa03410	Base excision repair	1/223	44/9376	0.95556461475744	MBD4	-0.0461130938809681
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	1/223	44/9376	0.95556461475744	HLA-A	-0.0461130938809681
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	3/223	142/9376	0.888271332028043	ACP5/SQSTM1/IL1R1	-0.209396875341476
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	1/223	45/9376	0.934329845540608	ABCA5	-0.0689233754616833
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	1/223	45/9376	0.934329845540608	HLA-A	-0.0689233754616833
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	3/223	144/9376	0.87593423019432	TCF7L2/LPIN1/ADH1B	-0.234175610594861
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	3/223	144/9376	0.87593423019432	RBPJ/PLCB1/VDAC2	-0.234175610594861
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	2/223	97/9376	0.866903980398502	GNGT1/PLCB1	-0.205663245928982
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	2/223	98/9376	0.858058021414844	CFL2/BIN1	-0.220471799597128
Metabolism	Amino acid metabolism	hsa00280	Valine, leucine and isoleucine degradation	1/223	48/9376	0.87593423019432	AUH	-0.134503833738318
NA	NA	hsa03272	Virion - Hepatitis viruses	1/223	48/9376	0.87593423019432	TSG101	-0.134503833738318
Organismal Systems	Digestive system	hsa04973	Carbohydrate digestion and absorption	1/223	48/9376	0.87593423019432	PLCB1	-0.134503833738318
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	2/223	99/9376	0.84939076867328	PDGFRA/PDGFD	-0.235137420466136
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	3/223	148/9376	0.85226033208096	TCF7L2/GADD45G/KIT	-0.282768170397133
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	2/223	100/9376	0.840896860986547	KIT/IL1R1	-0.249663305770895
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	3/223	150/9376	0.840896860986547	TCF7L2/GADD45G/MET	-0.306601299364939
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	1/223	50/9376	0.840896860986547	AOC1	-0.176064737383669
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	2/223	103/9376	0.816404719404415	SLC15A1/SLC3A2	-0.292432969471745
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	2/223	103/9376	0.816404719404415	PLCB1/CCL3	-0.292432969471745
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	5/223	248/9376	0.847678287284826	RPS3/IL18/TCF7L2/HSP90AB1/SKP1	-0.379451415764528
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	1/223	51/9376	0.824408687241713	LPCAT2	-0.196254684565807
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	2/223	104/9376	0.808554674025526	LPIN1/LPCAT2	-0.306429847098879
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	3/223	154/9376	0.819055384077806	PLCB1/PPP1CB/CACNB2	-0.353386378267369
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	4/223	205/9376	0.82038718145029	HLA-A/GADD45G/B2M/RBPJ	-0.405846916214031
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	4/223	205/9376	0.82038718145029	HLA-A/IL6ST/HDAC9/RBPJ	-0.405846916214031
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	3/223	157/9376	0.803404644254663	TCF7L2/PPP1CB/BMP5	-0.387737237126925
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	1/223	54/9376	0.778608204617173	HLA-A	-0.254659681375688
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	2/223	108/9376	0.778608204617173	EEF1A1/SAP18	-0.361190838421413
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	2/223	109/9376	0.771465010079401	CCL4/CCL3	-0.374587006151069
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	2/223	110/9376	0.764451691805952	HSP90AB1/SPDYE2	-0.387870296792845
Environmental Information Processing	Signal transduction	hsa04340	Hedgehog signaling pathway	1/223	56/9376	0.750800768737988	CDON	-0.291936968618052
Metabolism	Global and overview maps	hsa01212	Fatty acid metabolism	1/223	57/9376	0.737628825426796	ELOVL2	-0.31011675435312
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	2/223	115/9376	0.731214661727432	GNGT1/PLCB1	-0.45267018600405
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/223	60/9376	0.700747384155456	PLCB1	-0.362957002124381
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	3/223	170/9376	0.741967818517542	TCF7L2/GADD45G/MET	-0.529930831997555
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	1/223	62/9376	0.678142629827861	CRYAB	-0.396869318060125
Environmental Information Processing	Signal transduction	hsa04330	Notch signaling pathway	1/223	62/9376	0.678142629827861	RBPJ	-0.396869318060125
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	7/223	368/9376	0.799766036264379	HNRNPA1/ANG/GPX3/COX7A2L/DDIT3/SQSTM1/SRSF7	-0.611651159922053
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	4/223	224/9376	0.750800768737988	HLA-A/B2M/VDAC2/IL1R1	-0.589208549985293
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	2/223	122/9376	0.689259722120121	THRB/PLCB1	-0.539223804268373
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	1/223	65/9376	0.646843739220421	LPIN1	-0.445945476944862
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	1/223	65/9376	0.646843739220421	PLCB1	-0.445945476944862
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	1/223	66/9376	0.63704307650496	HSD17B11	-0.461858085430023
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	2/223	125/9376	0.672717488789238	PLCB1/CTSD	-0.574962874880478
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	6/223	333/9376	0.75756473962752	HLA-A/TCF7L2/ATP6V0C/ATP6V0E1/RBPJ/ATP6V1B2	-0.70310141961028
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/223	69/9376	0.609345551439527	PPP1CB	-0.508356991845944
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	2/223	128/9376	0.65695067264574	PDE1C/PDE4B	-0.60994964788845
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/223	70/9376	0.600640614990391	JAK2	-0.523465096680025
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	1/223	70/9376	0.600640614990391	SULT1A1	-0.523465096680025
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	3/223	184/9376	0.685513745369468	SEMA6D/CFL2/MET	-0.672452961439801
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	1/223	73/9376	0.575956754100375	ADH1B	-0.56769675052136
Genetic Information Processing	Transcription	hsa03040	Spliceosome	4/223	243/9376	0.692096181881932	HNRNPA1/PCBP1/SYF2/SRSF7	-0.759045519166214
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	1/223	75/9376	0.560597907324365	GLUL	-0.596326719304547
Human Diseases	Substance dependence	hsa05034	Alcoholism	3/223	191/9376	0.660390204963257	GNGT1/HDAC9/PPP1CB	-0.740139614422624
Human Diseases	Infectious disease: viral	hsa05162	Measles	2/223	136/9376	0.618306515431285	EIF3H/RACK1	-0.699849334259444
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	1/223	76/9376	0.553221619070097	PLIN2	-0.61039899566339
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/223	76/9376	0.553221619070097	PLCB1	-0.61039899566339
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	1/223	77/9376	0.546036922718537	GADD45G	-0.624315487350302
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/223	77/9376	0.546036922718537	GADD45G	-0.624315487350302
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	3/223	195/9376	0.646843739220421	HDAC9/PLCB1/VDAC2	-0.777849470453772
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	1/223	78/9376	0.539036449350351	PLCB1	-0.638080474334789
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	1/223	78/9376	0.539036449350351	PABPC1	-0.638080474334789
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	1/223	79/9376	0.532213203156042	ADH1B	-0.65169806050628
NA	NA	hsa04082	Neuroactive ligand signaling	3/223	199/9376	0.633841855014985	GNGT1/PLCB1/GRIK1	-0.814894168827767
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	3/223	200/9376	0.63067264573991	RPS3/IL18/IL1R1	-0.824054829217281
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	2/223	144/9376	0.58395615346288	IL6ST/JAK2	-0.785287690147426
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	5/223	308/9376	0.682546153398171	GPX3/COX7A2L/PLCB1/CLTC/VDAC2	-0.884212265239307
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	1/223	82/9376	0.512741988406431	CES1	-0.691705006807449
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	1/223	83/9376	0.506564374088281	PRDX1	-0.704770826374604
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	2/223	149/9376	0.564360309386944	GNGT1/PLCB1	-0.836655467289343
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/223	86/9376	0.488893523829388	PLCB1	-0.743205801381021
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	2/223	154/9376	0.546036922718537	DHFR/NAPRT	-0.886593762019357
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/223	90/9376	0.467164922770304	SESN1	-0.792786161810113
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	1/223	90/9376	0.467164922770304	JAK2	-0.792786161810113
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	2/223	157/9376	0.535603096169775	BSG/JAK2	-0.915911628424623
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	2/223	157/9376	0.535603096169775	COX7A2L/DDIT3	-0.915911628424623
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	3/223	217/9376	0.581265111281023	PTGES3/HSP90AB1/JAK2	-0.974095020993786
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/223	93/9376	0.452095086551907	PLCB1	-0.828817347889824
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/223	93/9376	0.452095086551907	GADD45G	-0.828817347889824
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	1/223	94/9376	0.447285564354546	HSP90AB1	-0.840621107755371
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	4/223	275/9376	0.611561353444761	C7/COX7A2L/DDIT3/VDAC2	-1.02047074897392
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	2/223	160/9376	0.525560538116592	HLA-A/ALCAM	-0.944769580451499
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/223	98/9376	0.429029010707422	PLCB1	-0.886862384066073
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	1/223	99/9376	0.42469538433664	MMP2	-0.898189587170044
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	1/223	99/9376	0.42469538433664	CFD	-0.898189587170044
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	3/223	226/9376	0.55811738561054	VIPR2/PPP1CB/PDE4B	-1.04955916638935
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	3/223	227/9376	0.555658718713577	COX7A2L/MET/VDAC2	-1.05778917023868
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	1/223	102/9376	0.412204343620856	PLCB1	-0.931642412005981
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	2/223	173/9376	0.486067549703206	IL18/JAK2	-1.06492916101163
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/223	107/9376	0.392942458404929	PLCB1	-0.985738331998499
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	1/223	112/9376	0.375400384368994	JAK2	-1.03792934152749
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	1/223	116/9376	0.362455543528684	ACSS1	-1.07842591024563
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/223	116/9376	0.362455543528684	MMP2	-1.07842591024563
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/223	117/9376	0.359357632900234	INO80C	-1.08838584142432
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	1/223	119/9376	0.353318008817877	VEGFC	-1.10811658322803
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	3/223	268/9376	0.470651228164112	COX7A2L/DDIT3/VDAC2	-1.37231602374828
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	1/223	133/9376	0.316126639468627	HLA-A	-1.23979924958239
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	1/223	138/9376	0.304672775719763	IL18	-1.28438769600568
NA	NA	hsa04519	Cadherin signaling	5/223	404/9376	0.520356968432269	GJA1/TCF7L2/PDGFRA/MET/PPP1CB	-1.53822734635082
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	1/223	143/9376	0.294019881463828	C7	-1.32783896990669
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	6/223	480/9376	0.525560538116592	GPX3/COX7A2L/DDIT3/PLCB1/SQSTM1/VDAC2	-1.66556035460856
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	1/223	156/9376	0.269518224675175	EIF3E	-1.43602685755404
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	2/223	235/9376	0.357828451483637	RPS6/COX7A2L	-1.55612498369663
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	1/223	163/9376	0.257943822388511	JAK2	-1.49171683171301
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	1/223	170/9376	0.247322606172514	NEDD4L	-1.54580314457353
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	4/223	388/9376	0.433451990199251	COX7A2L/DDIT3/PLCB1/VDAC2	-1.77900589727205
Cellular Processes	Cell motility	hsa04814	Motor proteins	1/223	194/9376	0.216725995099626	TNNC1	-1.72068856598939
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	2/223	323/9376	0.260339585444751	PDGFRA/MET	-2.11151278850455
NA	NA	hsa04517	IgSF CAM signaling	1/223	299/9376	0.140618204178352	PMP22	-2.3572568955134
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	1/223	449/9376	0.0936410758336912	PDE1C	-3.07204064160235