ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 42/352 175/18639 0.24 12.7084090909091 1.95151126804418e-34 1.41679718060007e-31 GO:0019843 rRNA binding 15/352 65/18639 0.230769230769231 12.2196241258741 9.08424575534826e-13 3.29758120919142e-10 GO:0045296 cadherin binding 21/352 334/18639 0.062874251497006 3.32929878878606 1.66251712523061e-06 0.000402329144305809 GO:0048027 mRNA 5'-UTR binding 6/352 24/18639 0.25 13.2379261363636 4.38926199959058e-06 0.00079665105292569 GO:0008135 translation factor activity, RNA binding 9/352 83/18639 0.108433734939759 5.74175109529025 2.65204301903893e-05 0.00353511125462561 GO:0180051 translation factor activity 9/352 84/18639 0.107142857142857 5.67339691558442 2.92157954927737e-05 0.00353511125462561 GO:0008198 ferrous iron binding 5/352 26/18639 0.192307692307692 10.1830201048951 0.000110788100016322 0.0107477843423224 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 7/352 59/18639 0.11864406779661 6.28240562403698 0.000118432885314847 0.0107477843423224 GO:0003743 translation initiation factor activity 6/352 51/18639 0.117647058823529 6.22961229946524 0.000382414423325497 0.0308480968149234 GO:0017046 peptide hormone binding 6/352 53/18639 0.113207547169811 5.99453259005146 0.000472305827605983 0.0342894030841943 GO:0004601 peroxidase activity 6/352 57/18639 0.105263157894737 5.57386363636364 0.000700850199517684 0.0462561131681671 GO:0008199 ferric iron binding 3/352 11/18639 0.272727272727273 14.4413739669421 0.000984503838283378 0.0549807528149025 GO:1990948 ubiquitin ligase inhibitor activity 3/352 11/18639 0.272727272727273 14.4413739669421 0.000984503838283378 0.0549807528149025 GO:0019838 growth factor binding 9/352 136/18639 0.0661764705882353 3.5041569184492 0.00112869231525605 0.0584923564824645 GO:0016209 antioxidant activity 7/352 86/18639 0.0813953488372093 4.31002246300211 0.00120851976203439 0.0584923564824645 GO:0070851 growth factor receptor binding 9/352 139/18639 0.0647482014388489 3.4285276324395 0.00131556846944888 0.0596939193012431 GO:0042562 hormone binding 7/352 94/18639 0.074468085106383 3.94321204061896 0.00202567444397373 0.0808114114434343 GO:0005161 platelet-derived growth factor receptor binding 3/352 14/18639 0.214285714285714 11.3467938311688 0.00208237649409944 0.0808114114434343 GO:0051082 unfolded protein binding 8/352 121/18639 0.0661157024793388 3.50093914350113 0.00211489919755544 0.0808114114434343 GO:0055105 ubiquitin-protein transferase inhibitor activity 3/352 15/18639 0.2 10.5903409090909 0.00256678201854203 0.0925612668235394 GO:0033218 amide binding 12/352 247/18639 0.048582995951417 2.57255244755245 0.00267739201555693 0.0925612668235394 GO:0003746 translation elongation factor activity 3/352 18/18639 0.166666666666667 8.82528409090909 0.00441430117561492 0.139338376238975 GO:0050811 GABA receptor binding 3/352 18/18639 0.166666666666667 8.82528409090909 0.00441430117561492 0.139338376238975 GO:0043022 ribosome binding 7/352 112/18639 0.0625 3.30948153409091 0.00538192539713272 0.162803243263265 GO:0043024 ribosomal small subunit binding 3/352 20/18639 0.15 7.94275568181818 0.00599748070562591 0.174166839691376 GO:0042169 SH2 domain binding 4/352 41/18639 0.0975609756097561 5.1660199556541 0.00730279127137254 0.196792840245462 GO:0030021 extracellular matrix structural constituent conferring compression resistance 3/352 22/18639 0.136363636363636 7.22068698347107 0.00787953590369819 0.196792840245462 GO:0042056 chemoattractant activity 4/352 42/18639 0.0952380952380952 5.04301948051948 0.00795372115136105 0.196792840245462 GO:0048487 beta-tubulin binding 4/352 42/18639 0.0952380952380952 5.04301948051948 0.00795372115136105 0.196792840245462 GO:0003697 single-stranded DNA binding 7/352 121/18639 0.0578512396694215 3.06332175056349 0.00813193554733314 0.196792840245462 GO:0004602 glutathione peroxidase activity 3/352 23/18639 0.130434782608696 6.90674407114624 0.00893645704181388 0.2089290228956 GO:0032934 sterol binding 5/352 68/18639 0.0735294117647059 3.89350768716578 0.00921305620331716 0.2089290228956 GO:0042625 ATPase-coupled ion transmembrane transporter activity 3/352 24/18639 0.125 6.61896306818182 0.0100723358145262 0.2089290228956 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 3/352 24/18639 0.125 6.61896306818182 0.0100723358145262 0.2089290228956 GO:0046961 proton-transporting ATPase activity, rotational mechanism 3/352 24/18639 0.125 6.61896306818182 0.0100723358145262 0.2089290228956 GO:0001664 G protein-coupled receptor binding 12/352 297/18639 0.0404040404040404 2.13946280991736 0.0111802227572505 0.219545679308954 GO:0099106 ion channel regulator activity 8/352 160/18639 0.05 2.64758522727273 0.0111889671273158 0.219545679308954 GO:0031625 ubiquitin protein ligase binding 12/352 302/18639 0.0397350993377483 2.10404124021674 0.0126252260048746 0.241208265251025 GO:0004857 enzyme inhibitor activity 15/352 416/18639 0.0360576923076923 1.90931626966783 0.013089836438015 0.242084170534666 GO:0030957 Tat protein binding 2/352 10/18639 0.2 10.5903409090909 0.014477936752754 0.242084170534666 GO:0031720 haptoglobin binding 2/352 10/18639 0.2 10.5903409090909 0.014477936752754 0.242084170534666 GO:0005006 epidermal growth factor receptor activity 4/352 50/18639 0.08 4.23613636363636 0.0145547383591451 0.242084170534666 GO:0005201 extracellular matrix structural constituent 8/352 168/18639 0.0476190476190476 2.52150974025974 0.0146717679111919 0.242084170534666 GO:0016247 channel regulator activity 8/352 168/18639 0.0476190476190476 2.52150974025974 0.0146717679111919 0.242084170534666 GO:0141108 transporter regulator activity 8/352 170/18639 0.0470588235294118 2.4918449197861 0.0156534011529935 0.252541538601629 GO:0019199 transmembrane receptor protein kinase activity 5/352 78/18639 0.0641025641025641 3.39434003496503 0.0160349727098341 0.253073699724773 GO:0008201 heparin binding 8/352 172/18639 0.0465116279069767 2.46286997885835 0.0166817501703439 0.25767980050361 GO:0004713 protein tyrosine kinase activity 7/352 140/18639 0.05 2.64758522727273 0.0171352381966136 0.259170477723781 GO:0001968 fibronectin binding 3/352 30/18639 0.1 5.29517045454546 0.0185955819832302 0.273754213473431 GO:0015485 cholesterol binding 4/352 54/18639 0.0740740740740741 3.92234848484848 0.0188535959692445 0.273754213473431 GO:0044389 ubiquitin-like protein ligase binding 12/352 322/18639 0.0372670807453416 1.97335544889893 0.019876556911575 0.278473417721265 GO:0042277 peptide binding 10/352 249/18639 0.0401606425702811 2.12657447973713 0.0203548930301388 0.278473417721265 GO:0004300 enoyl-CoA hydratase activity 2/352 12/18639 0.166666666666667 8.82528409090909 0.0207128988387718 0.278473417721265 GO:0045295 gamma-catenin binding 2/352 12/18639 0.166666666666667 8.82528409090909 0.0207128988387718 0.278473417721265 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 2/352 13/18639 0.153846153846154 8.14641608391609 0.0241771999048994 0.302631847085465 GO:0031994 insulin-like growth factor I binding 2/352 13/18639 0.153846153846154 8.14641608391609 0.0241771999048994 0.302631847085465 GO:0035673 oligopeptide transmembrane transporter activity 2/352 13/18639 0.153846153846154 8.14641608391609 0.0241771999048994 0.302631847085465 GO:0070700 BMP receptor binding 2/352 13/18639 0.153846153846154 8.14641608391609 0.0241771999048994 0.302631847085465 GO:0015459 potassium channel regulator activity 4/352 59/18639 0.0677966101694915 3.58994607087827 0.0252297199776882 0.310453842437316 GO:0004714 transmembrane receptor protein tyrosine kinase activity 4/352 60/18639 0.0666666666666667 3.53011363636364 0.0266423995878708 0.31117108867175 GO:0003727 single-stranded RNA binding 5/352 89/18639 0.0561797752808989 2.97481486210419 0.0267124413320391 0.31117108867175 GO:0005506 iron ion binding 7/352 154/18639 0.0454545454545455 2.40689566115702 0.0271834557090829 0.31117108867175 GO:0005344 oxygen carrier activity 2/352 14/18639 0.142857142857143 7.56452922077922 0.027859670473366 0.31117108867175 GO:0008494 translation activator activity 2/352 14/18639 0.142857142857143 7.56452922077922 0.027859670473366 0.31117108867175 GO:0098847 sequence-specific single stranded DNA binding 2/352 14/18639 0.142857142857143 7.56452922077922 0.027859670473366 0.31117108867175 GO:0008528 G protein-coupled peptide receptor activity 6/352 122/18639 0.0491803278688525 2.60418219076006 0.0283451760136131 0.311796936149744 GO:0055106 ubiquitin-protein transferase regulator activity 3/352 36/18639 0.0833333333333333 4.41264204545455 0.0301138594203154 0.323016858317127 GO:0043178 alcohol binding 5/352 92/18639 0.0543478260869565 2.87781002964427 0.0302550225421001 0.323016858317127 GO:0001653 peptide receptor activity 6/352 128/18639 0.046875 2.48211115056818 0.0346862246966557 0.364959407677856 GO:0016722 oxidoreductase activity, acting on metal ions 2/352 16/18639 0.125 6.61896306818182 0.0358416907299349 0.366493908027221 GO:0043023 ribosomal large subunit binding 2/352 16/18639 0.125 6.61896306818182 0.0358416907299349 0.366493908027221 GO:1901681 sulfur compound binding 10/352 275/18639 0.0363636363636364 1.92551652892562 0.0367188944592678 0.370248852464284 GO:0042626 ATPase-coupled transmembrane transporter activity 5/352 98/18639 0.0510204081632653 2.70161757884972 0.0381920642239465 0.377675157355982 GO:0015399 primary active transmembrane transporter activity 7/352 166/18639 0.0421686746987952 2.23290320372399 0.0384958149371111 0.377675157355982 GO:0008429 phosphatidylethanolamine binding 2/352 17/18639 0.117647058823529 6.22961229946524 0.0401232098482358 0.378304549997652 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/352 17/18639 0.117647058823529 6.22961229946524 0.0401232098482358 0.378304549997652 GO:1990226 histone methyltransferase binding 2/352 17/18639 0.117647058823529 6.22961229946524 0.0401232098482358 0.378304549997652 GO:0005539 glycosaminoglycan binding 9/352 242/18639 0.0371900826446281 1.96927826821938 0.0409354740904568 0.381014797303483 GO:0051087 protein-folding chaperone binding 6/352 134/18639 0.0447761194029851 2.37097184531886 0.041877584291506 0.384849698678903 GO:0002020 protease binding 6/352 136/18639 0.0441176470588235 2.33610461229947 0.0444682795851343 0.394756509900726 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 2/352 18/18639 0.111111111111111 5.88352272727273 0.0445868234323134 0.394756509900726 GO:0017128 phospholipid scramblase activity 2/352 18/18639 0.111111111111111 5.88352272727273 0.0445868234323134 0.394756509900726 GO:0005518 collagen binding 4/352 72/18639 0.0555555555555556 2.94176136363636 0.0472659456485098 0.40405053736137 GO:0008200 ion channel inhibitor activity 3/352 43/18639 0.0697674418604651 3.69430496828753 0.0473061923907941 0.40405053736137 GO:0048156 tau protein binding 3/352 43/18639 0.0697674418604651 3.69430496828753 0.0473061923907941 0.40405053736137 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 2/352 19/18639 0.105263157894737 5.57386363636364 0.0492241693393831 0.406099397049911 GO:0005520 insulin-like growth factor binding 2/352 19/18639 0.105263157894737 5.57386363636364 0.0492241693393831 0.406099397049911 GO:0097001 ceramide binding 2/352 19/18639 0.105263157894737 5.57386363636364 0.0492241693393831 0.406099397049911 GO:0016248 channel inhibitor activity 3/352 44/18639 0.0681818181818182 3.61034349173554 0.0500822131740989 0.408535806341525 GO:0043021 ribonucleoprotein complex binding 7/352 177/18639 0.0395480225988701 2.09413520801233 0.051249655758631 0.40858020649495 GO:0008009 chemokine activity 3/352 45/18639 0.0666666666666667 3.53011363636364 0.0529358426819489 0.40858020649495 GO:0141110 transporter inhibitor activity 3/352 45/18639 0.0666666666666667 3.53011363636364 0.0529358426819489 0.40858020649495 GO:0003725 double-stranded RNA binding 4/352 75/18639 0.0533333333333333 2.82409090909091 0.0534876348014021 0.40858020649495 GO:0005496 steroid binding 5/352 108/18639 0.0462962962962963 2.4514678030303 0.0540127720854797 0.40858020649495 GO:0016004 phospholipase activator activity 2/352 20/18639 0.1 5.29517045454546 0.0540271347431339 0.40858020649495 GO:0016505 peptidase activator activity involved in apoptotic process 2/352 20/18639 0.1 5.29517045454546 0.0540271347431339 0.40858020649495 GO:0098631 cell adhesion mediator activity 4/352 76/18639 0.0526315789473684 2.78693181818182 0.0556556463255905 0.412500788261037 GO:0019955 cytokine binding 6/352 144/18639 0.0416666666666667 2.20632102272727 0.055817542783834 0.412500788261037 GO:0070182 DNA polymerase binding 2/352 21/18639 0.0952380952380952 5.04301948051948 0.0589878497434377 0.412500788261037 GO:0072542 protein phosphatase activator activity 2/352 21/18639 0.0952380952380952 5.04301948051948 0.0589878497434377 0.412500788261037 GO:0003730 mRNA 3'-UTR binding 9/352 262/18639 0.0343511450381679 1.81895168285913 0.0615563325238776 0.412500788261037 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 3/352 48/18639 0.0625 3.30948153409091 0.0619528041190312 0.412500788261037 GO:0016835 carbon-oxygen lyase activity 4/352 79/18639 0.0506329113924051 2.68109896432681 0.0624395541278948 0.412500788261037 GO:0005004 GPI-linked ephrin receptor activity 3/352 49/18639 0.0612244897959184 3.24194109461967 0.0651070608152337 0.412500788261037 GO:0005008 hepatocyte growth factor receptor activity 3/352 49/18639 0.0612244897959184 3.24194109461967 0.0651070608152337 0.412500788261037 GO:0005009 insulin receptor activity 3/352 49/18639 0.0612244897959184 3.24194109461967 0.0651070608152337 0.412500788261037 GO:0005011 macrophage colony-stimulating factor receptor activity 3/352 49/18639 0.0612244897959184 3.24194109461967 0.0651070608152337 0.412500788261037 GO:0005018 platelet-derived growth factor alpha-receptor activity 3/352 49/18639 0.0612244897959184 3.24194109461967 0.0651070608152337 0.412500788261037 GO:0005020 stem cell factor receptor activity 3/352 49/18639 0.0612244897959184 3.24194109461967 0.0651070608152337 0.412500788261037 GO:0008288 boss receptor activity 3/352 49/18639 0.0612244897959184 3.24194109461967 0.0651070608152337 0.412500788261037 GO:0036332 placental growth factor receptor activity 3/352 49/18639 0.0612244897959184 3.24194109461967 0.0651070608152337 0.412500788261037 GO:0038062 protein tyrosine kinase collagen receptor activity 3/352 49/18639 0.0612244897959184 3.24194109461967 0.0651070608152337 0.412500788261037 GO:0060175 brain-derived neurotrophic factor receptor activity 3/352 49/18639 0.0612244897959184 3.24194109461967 0.0651070608152337 0.412500788261037 GO:0061134 peptidase regulator activity 8/352 226/18639 0.0353982300884956 1.87439662107804 0.0656639766569012 0.412500788261037 GO:0035401 histone H3Y41 kinase activity 5/352 115/18639 0.0434782608695652 2.30224802371541 0.0670398998361303 0.412500788261037 GO:0140801 histone H2AXY142 kinase activity 5/352 115/18639 0.0434782608695652 2.30224802371541 0.0670398998361303 0.412500788261037 GO:0005007 fibroblast growth factor receptor activity 3/352 50/18639 0.06 3.17710227272727 0.0683338048017926 0.412500788261037 GO:0005017 platelet-derived growth factor receptor activity 3/352 50/18639 0.06 3.17710227272727 0.0683338048017926 0.412500788261037 GO:0005019 platelet-derived growth factor beta-receptor activity 3/352 50/18639 0.06 3.17710227272727 0.0683338048017926 0.412500788261037 GO:0048020 CCR chemokine receptor binding 3/352 50/18639 0.06 3.17710227272727 0.0683338048017926 0.412500788261037 GO:0017134 fibroblast growth factor binding 2/352 23/18639 0.0869565217391304 4.60449604743083 0.0693522262784209 0.412500788261037 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 2/352 23/18639 0.0869565217391304 4.60449604743083 0.0693522262784209 0.412500788261037 GO:0005010 insulin-like growth factor receptor activity 3/352 51/18639 0.0588235294117647 3.11480614973262 0.0716318916135962 0.412500788261037 GO:0005021 vascular endothelial growth factor receptor activity 3/352 51/18639 0.0588235294117647 3.11480614973262 0.0716318916135962 0.412500788261037 GO:0005030 neurotrophin receptor activity 3/352 51/18639 0.0588235294117647 3.11480614973262 0.0716318916135962 0.412500788261037 GO:0004860 protein kinase inhibitor activity 4/352 84/18639 0.0476190476190476 2.52150974025974 0.0746643878761395 0.412500788261037 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 2/352 24/18639 0.0833333333333333 4.41264204545455 0.0747413072296841 0.412500788261037 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 2/352 24/18639 0.0833333333333333 4.41264204545455 0.0747413072296841 0.412500788261037 GO:0050431 transforming growth factor beta binding 2/352 24/18639 0.0833333333333333 4.41264204545455 0.0747413072296841 0.412500788261037 GO:0060229 lipase activator activity 2/352 24/18639 0.0833333333333333 4.41264204545455 0.0747413072296841 0.412500788261037 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 2/352 24/18639 0.0833333333333333 4.41264204545455 0.0747413072296841 0.412500788261037 GO:0005080 protein kinase C binding 3/352 52/18639 0.0576923076923077 3.05490603146853 0.0750001433201885 0.412500788261037 GO:0005126 cytokine receptor binding 9/352 275/18639 0.0327272727272727 1.73296487603306 0.0779894634167434 0.415660707461959 GO:0005003 ephrin receptor activity 3/352 53/18639 0.0566037735849057 2.99726629502573 0.0784373511326287 0.415660707461959 GO:0005005 transmembrane-ephrin receptor activity 3/352 53/18639 0.0566037735849057 2.99726629502573 0.0784373511326287 0.415660707461959 GO:0016860 intramolecular oxidoreductase activity 3/352 53/18639 0.0566037735849057 2.99726629502573 0.0784373511326287 0.415660707461959 GO:0038064 collagen receptor activity 3/352 53/18639 0.0566037735849057 2.99726629502573 0.0784373511326287 0.415660707461959 GO:0019211 phosphatase activator activity 2/352 25/18639 0.08 4.23613636363636 0.0802589648592154 0.422231945563698 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 3/352 54/18639 0.0555555555555556 2.94176136363636 0.0819422779069455 0.427986286046348 GO:0008081 phosphoric diester hydrolase activity 4/352 87/18639 0.0459770114942529 2.43456112852665 0.0825368821171773 0.428012688693362 GO:0098632 cell-cell adhesion mediator activity 3/352 55/18639 0.0545454545454545 2.88827479338843 0.0855136605474618 0.430084669240232 GO:0004112 cyclic-nucleotide phosphodiesterase activity 2/352 26/18639 0.0769230769230769 4.07320804195804 0.0858984532229114 0.430084669240232 GO:0008143 poly(A) binding 2/352 26/18639 0.0769230769230769 4.07320804195804 0.0858984532229114 0.430084669240232 GO:0050750 low-density lipoprotein particle receptor binding 2/352 26/18639 0.0769230769230769 4.07320804195804 0.0858984532229114 0.430084669240232 GO:0097602 cullin family protein binding 2/352 26/18639 0.0769230769230769 4.07320804195804 0.0858984532229114 0.430084669240232 GO:0008083 growth factor activity 6/352 162/18639 0.037037037037037 1.96117424242424 0.0871908985628888 0.433565701072995 GO:0019210 kinase inhibitor activity 4/352 90/18639 0.0444444444444444 2.35340909090909 0.0908003642151676 0.446578844969446 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 2/352 27/18639 0.0740740740740741 3.92234848484848 0.0916532340226548 0.446578844969446 GO:0023026 MHC class II protein complex binding 2/352 27/18639 0.0740740740740741 3.92234848484848 0.0916532340226548 0.446578844969446 GO:0016504 peptidase activator activity 3/352 57/18639 0.0526315789473684 2.78693181818182 0.0928506250302648 0.449397025146481 GO:0031490 chromatin DNA binding 5/352 128/18639 0.0390625 2.06842595880682 0.0954322962378667 0.458833424295969 GO:0045499 chemorepellent activity 2/352 28/18639 0.0714285714285714 3.78226461038961 0.0975169712063839 0.459722864258667 GO:0046625 sphingolipid binding 2/352 28/18639 0.0714285714285714 3.78226461038961 0.0975169712063839 0.459722864258667 GO:0097718 disordered domain specific binding 2/352 28/18639 0.0714285714285714 3.78226461038961 0.0975169712063839 0.459722864258667 GO:0016798 hydrolase activity, acting on glycosyl bonds 5/352 130/18639 0.0384615384615385 2.03660402097902 0.100269753469314 0.469650587217562 GO:0031072 heat shock protein binding 5/352 131/18639 0.0381679389312977 2.02105742539903 0.102733877212766 0.478107659336335 GO:0051861 glycolipid binding 2/352 29/18639 0.0689655172413793 3.65184169278997 0.103483525697133 0.478528915007126 GO:0015026 coreceptor activity 3/352 61/18639 0.0491803278688525 2.60418219076006 0.108264088162495 0.491248300037322 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 3/352 61/18639 0.0491803278688525 2.60418219076006 0.108264088162495 0.491248300037322 GO:0016836 hydro-lyase activity 3/352 61/18639 0.0491803278688525 2.60418219076006 0.108264088162495 0.491248300037322 GO:0033612 receptor serine/threonine kinase binding 2/352 30/18639 0.0666666666666667 3.53011363636364 0.109546950248126 0.493981899876644 GO:0017147 Wnt-protein binding 2/352 31/18639 0.0645161290322581 3.41623900293255 0.115701484421056 0.514923200820341 GO:0070325 lipoprotein particle receptor binding 2/352 31/18639 0.0645161290322581 3.41623900293255 0.115701484421056 0.514923200820341 GO:1901682 sulfur compound transmembrane transporter activity 3/352 63/18639 0.0476190476190476 2.52150974025974 0.116318739579251 0.514923200820341 GO:0031369 translation initiation factor binding 2/352 32/18639 0.0625 3.30948153409091 0.12194154968476 0.533310632958649 GO:0070717 poly-purine tract binding 2/352 32/18639 0.0625 3.30948153409091 0.12194154968476 0.533310632958649 GO:0140416 transcription regulator inhibitor activity 2/352 33/18639 0.0606060606060606 3.20919421487603 0.128261744631549 0.557592973667692 GO:0020037 heme binding 5/352 142/18639 0.0352112676056338 1.86449663892446 0.131759654850939 0.569389937034416 GO:0016500 protein-hormone receptor activity 3/352 67/18639 0.0447761194029851 2.37097184531886 0.133067974883382 0.571641122871808 GO:0008376 acetylgalactosaminyltransferase activity 2/352 34/18639 0.0588235294117647 3.11480614973262 0.13465684030852 0.571700971134419 GO:0019825 oxygen binding 2/352 34/18639 0.0588235294117647 3.11480614973262 0.13465684030852 0.571700971134419 GO:0008013 beta-catenin binding 4/352 106/18639 0.0377358490566038 1.99817753001715 0.140948637501362 0.573684736985364 GO:0005154 epidermal growth factor receptor binding 2/352 35/18639 0.0571428571428571 3.02581168831169 0.141121775661228 0.573684736985364 GO:0043015 gamma-tubulin binding 2/352 35/18639 0.0571428571428571 3.02581168831169 0.141121775661228 0.573684736985364 GO:0061631 ubiquitin conjugating enzyme activity 2/352 35/18639 0.0571428571428571 3.02581168831169 0.141121775661228 0.573684736985364 GO:0031406 carboxylic acid binding 6/352 187/18639 0.0320855614973262 1.69898517258143 0.143688169103941 0.573684736985364 GO:0003712 transcription coregulator activity 13/352 495/18639 0.0262626262626263 1.39065082644628 0.146030000978005 0.573684736985364 GO:0097110 scaffold protein binding 3/352 70/18639 0.0428571428571429 2.26935876623377 0.146145204163882 0.573684736985364 GO:0043177 organic acid binding 6/352 189/18639 0.0317460317460317 1.68100649350649 0.148805061596489 0.573684736985364 GO:0019213 deacetylase activity 2/352 37/18639 0.0540540540540541 2.8622542997543 0.154241734096529 0.573684736985364 GO:0022829 wide pore channel activity 2/352 37/18639 0.0540540540540541 2.8622542997543 0.154241734096529 0.573684736985364 GO:0023023 MHC protein complex binding 2/352 37/18639 0.0540540540540541 2.8622542997543 0.154241734096529 0.573684736985364 GO:0043394 proteoglycan binding 2/352 37/18639 0.0540540540540541 2.8622542997543 0.154241734096529 0.573684736985364 GO:0042379 chemokine receptor binding 3/352 72/18639 0.0416666666666667 2.20632102272727 0.15508740968161 0.573684736985364 GO:0005501 retinoid binding 2/352 38/18639 0.0526315789473684 2.78693181818182 0.160887435077856 0.573684736985364 GO:0019840 isoprenoid binding 2/352 38/18639 0.0526315789473684 2.78693181818182 0.160887435077856 0.573684736985364 GO:0042887 amide transmembrane transporter activity 2/352 38/18639 0.0526315789473684 2.78693181818182 0.160887435077856 0.573684736985364 GO:0046906 tetrapyrrole binding 5/352 152/18639 0.0328947368421053 1.74183238636364 0.160977246040059 0.573684736985364 GO:0003684 damaged DNA binding 3/352 74/18639 0.0405405405405405 2.14669072481573 0.164195621327569 0.573684736985364 GO:0048029 monosaccharide binding 3/352 74/18639 0.0405405405405405 2.14669072481573 0.164195621327569 0.573684736985364 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 2/352 39/18639 0.0512820512820513 2.71547202797203 0.1675843231661 0.573684736985364 GO:0005131 growth hormone receptor binding 1/352 10/18639 0.1 5.29517045454546 0.173622705200791 0.573684736985364 GO:0005381 iron ion transmembrane transporter activity 1/352 10/18639 0.1 5.29517045454546 0.173622705200791 0.573684736985364 GO:0008140 cAMP response element binding protein binding 1/352 10/18639 0.1 5.29517045454546 0.173622705200791 0.573684736985364 GO:0008401 retinoic acid 4-hydroxylase activity 1/352 10/18639 0.1 5.29517045454546 0.173622705200791 0.573684736985364 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/352 10/18639 0.1 5.29517045454546 0.173622705200791 0.573684736985364 GO:0019531 oxalate transmembrane transporter activity 1/352 10/18639 0.1 5.29517045454546 0.173622705200791 0.573684736985364 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/352 10/18639 0.1 5.29517045454546 0.173622705200791 0.573684736985364 GO:0032356 oxidized DNA binding 1/352 10/18639 0.1 5.29517045454546 0.173622705200791 0.573684736985364 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/352 10/18639 0.1 5.29517045454546 0.173622705200791 0.573684736985364 GO:0043208 glycosphingolipid binding 1/352 10/18639 0.1 5.29517045454546 0.173622705200791 0.573684736985364 GO:0043295 glutathione binding 1/352 10/18639 0.1 5.29517045454546 0.173622705200791 0.573684736985364 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/352 10/18639 0.1 5.29517045454546 0.173622705200791 0.573684736985364 GO:0051880 G-quadruplex DNA binding 1/352 10/18639 0.1 5.29517045454546 0.173622705200791 0.573684736985364 GO:0070513 death domain binding 1/352 10/18639 0.1 5.29517045454546 0.173622705200791 0.573684736985364 GO:0098505 G-rich strand telomeric DNA binding 1/352 10/18639 0.1 5.29517045454546 0.173622705200791 0.573684736985364 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/352 10/18639 0.1 5.29517045454546 0.173622705200791 0.573684736985364 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/352 10/18639 0.1 5.29517045454546 0.173622705200791 0.573684736985364 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/352 10/18639 0.1 5.29517045454546 0.173622705200791 0.573684736985364 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/352 40/18639 0.05 2.64758522727273 0.174328112210818 0.573684736985364 GO:0019207 kinase regulator activity 8/352 287/18639 0.0278745644599303 1.47600570161546 0.177416846263086 0.573684736985364 GO:1990782 protein tyrosine kinase binding 4/352 117/18639 0.0341880341880342 1.81031468531469 0.180523968297012 0.573684736985364 GO:0017080 sodium channel regulator activity 2/352 41/18639 0.0487804878048781 2.58300997782705 0.181114658842196 0.573684736985364 GO:0061650 ubiquitin-like protein conjugating enzyme activity 2/352 41/18639 0.0487804878048781 2.58300997782705 0.181114658842196 0.573684736985364 GO:0022853 active monoatomic ion transmembrane transporter activity 4/352 118/18639 0.0338983050847458 1.79497303543914 0.18429278021316 0.573684736985364 GO:0033293 monocarboxylic acid binding 3/352 79/18639 0.0379746835443038 2.01082422324511 0.187618724416419 0.573684736985364 GO:0004520 DNA endonuclease activity 2/352 42/18639 0.0476190476190476 2.52150974025974 0.187939958632636 0.573684736985364 GO:0035198 miRNA binding 2/352 42/18639 0.0476190476190476 2.52150974025974 0.187939958632636 0.573684736985364 GO:0051879 Hsp90 protein binding 2/352 42/18639 0.0476190476190476 2.52150974025974 0.187939958632636 0.573684736985364 GO:0003953 NAD+ nucleosidase activity 1/352 11/18639 0.0909090909090909 4.81379132231405 0.189237327980829 0.573684736985364 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 1/352 11/18639 0.0909090909090909 4.81379132231405 0.189237327980829 0.573684736985364 GO:0005114 type II transforming growth factor beta receptor binding 1/352 11/18639 0.0909090909090909 4.81379132231405 0.189237327980829 0.573684736985364 GO:0008271 secondary active sulfate transmembrane transporter activity 1/352 11/18639 0.0909090909090909 4.81379132231405 0.189237327980829 0.573684736985364 GO:0008432 JUN kinase binding 1/352 11/18639 0.0909090909090909 4.81379132231405 0.189237327980829 0.573684736985364 GO:0010854 adenylate cyclase regulator activity 1/352 11/18639 0.0909090909090909 4.81379132231405 0.189237327980829 0.573684736985364 GO:0015173 aromatic amino acid transmembrane transporter activity 1/352 11/18639 0.0909090909090909 4.81379132231405 0.189237327980829 0.573684736985364 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/352 11/18639 0.0909090909090909 4.81379132231405 0.189237327980829 0.573684736985364 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/352 11/18639 0.0909090909090909 4.81379132231405 0.189237327980829 0.573684736985364 GO:0042608 T cell receptor binding 1/352 11/18639 0.0909090909090909 4.81379132231405 0.189237327980829 0.573684736985364 GO:0043522 leucine zipper domain binding 1/352 11/18639 0.0909090909090909 4.81379132231405 0.189237327980829 0.573684736985364 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 1/352 11/18639 0.0909090909090909 4.81379132231405 0.189237327980829 0.573684736985364 GO:0048185 activin binding 1/352 11/18639 0.0909090909090909 4.81379132231405 0.189237327980829 0.573684736985364 GO:0048407 platelet-derived growth factor binding 1/352 11/18639 0.0909090909090909 4.81379132231405 0.189237327980829 0.573684736985364 GO:0050786 RAGE receptor binding 1/352 11/18639 0.0909090909090909 4.81379132231405 0.189237327980829 0.573684736985364 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/352 11/18639 0.0909090909090909 4.81379132231405 0.189237327980829 0.573684736985364 GO:0140537 transcription regulator activator activity 1/352 11/18639 0.0909090909090909 4.81379132231405 0.189237327980829 0.573684736985364 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/352 11/18639 0.0909090909090909 4.81379132231405 0.189237327980829 0.573684736985364 GO:1900750 oligopeptide binding 1/352 11/18639 0.0909090909090909 4.81379132231405 0.189237327980829 0.573684736985364 GO:0004866 endopeptidase inhibitor activity 5/352 161/18639 0.031055900621118 1.64446287408244 0.189290738364993 0.573684736985364 GO:0003714 transcription corepressor activity 6/352 204/18639 0.0294117647058824 1.55740307486631 0.189647846937311 0.573684736985364 GO:0001618 virus receptor activity 3/352 81/18639 0.037037037037037 1.96117424242424 0.197219934517519 0.581831877906322 GO:0015101 organic cation transmembrane transporter activity 3/352 81/18639 0.037037037037037 1.96117424242424 0.197219934517519 0.581831877906322 GO:0005516 calmodulin binding 6/352 207/18639 0.0289855072463768 1.53483201581028 0.198295871676167 0.581831877906322 GO:0140272 exogenous protein binding 3/352 82/18639 0.0365853658536585 1.93725748337029 0.202064803444147 0.581831877906322 GO:0003720 telomerase activity 1/352 12/18639 0.0833333333333333 4.41264204545455 0.204557730630106 0.581831877906322 GO:0015166 polyol transmembrane transporter activity 1/352 12/18639 0.0833333333333333 4.41264204545455 0.204557730630106 0.581831877906322 GO:0016208 AMP binding 1/352 12/18639 0.0833333333333333 4.41264204545455 0.204557730630106 0.581831877906322 GO:0031543 peptidyl-proline dioxygenase activity 1/352 12/18639 0.0833333333333333 4.41264204545455 0.204557730630106 0.581831877906322 GO:0043047 single-stranded telomeric DNA binding 1/352 12/18639 0.0833333333333333 4.41264204545455 0.204557730630106 0.581831877906322 GO:0070008 serine-type exopeptidase activity 1/352 12/18639 0.0833333333333333 4.41264204545455 0.204557730630106 0.581831877906322 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/352 12/18639 0.0833333333333333 4.41264204545455 0.204557730630106 0.581831877906322 GO:0140900 chloride:bicarbonate antiporter activity 1/352 12/18639 0.0833333333333333 4.41264204545455 0.204557730630106 0.581831877906322 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/352 12/18639 0.0833333333333333 4.41264204545455 0.204557730630106 0.581831877906322 GO:1990459 transferrin receptor binding 1/352 12/18639 0.0833333333333333 4.41264204545455 0.204557730630106 0.581831877906322 GO:1990817 poly(A) RNA polymerase activity 1/352 12/18639 0.0833333333333333 4.41264204545455 0.204557730630106 0.581831877906322 GO:0004715 non-membrane spanning protein tyrosine kinase activity 2/352 45/18639 0.0444444444444444 2.35340909090909 0.208610338807039 0.581831877906322 GO:0042605 peptide antigen binding 2/352 45/18639 0.0444444444444444 2.35340909090909 0.208610338807039 0.581831877906322 GO:0140303 intramembrane lipid transporter activity 2/352 45/18639 0.0444444444444444 2.35340909090909 0.208610338807039 0.581831877906322 GO:0019887 protein kinase regulator activity 7/352 255/18639 0.0274509803921569 1.45357620320856 0.208626208640672 0.581831877906322 GO:0003713 transcription coactivator activity 7/352 256/18639 0.02734375 1.44789817116477 0.211309074916291 0.581831877906322 GO:0030276 clathrin binding 2/352 46/18639 0.0434782608695652 2.30224802371541 0.215553256628297 0.581831877906322 GO:0030291 protein serine/threonine kinase inhibitor activity 2/352 46/18639 0.0434782608695652 2.30224802371541 0.215553256628297 0.581831877906322 GO:0030414 peptidase inhibitor activity 5/352 169/18639 0.029585798816568 1.56661847767617 0.21583299176484 0.581831877906322 GO:0004519 endonuclease activity 4/352 127/18639 0.031496062992126 1.66777022190408 0.219286422885065 0.581831877906322 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/352 13/18639 0.0769230769230769 4.07320804195804 0.219589441523874 0.581831877906322 GO:0003964 RNA-directed DNA polymerase activity 1/352 13/18639 0.0769230769230769 4.07320804195804 0.219589441523874 0.581831877906322 GO:0005172 vascular endothelial growth factor receptor binding 1/352 13/18639 0.0769230769230769 4.07320804195804 0.219589441523874 0.581831877906322 GO:0005542 folic acid binding 1/352 13/18639 0.0769230769230769 4.07320804195804 0.219589441523874 0.581831877906322 GO:0008253 5'-nucleotidase activity 1/352 13/18639 0.0769230769230769 4.07320804195804 0.219589441523874 0.581831877906322 GO:0017154 semaphorin receptor activity 1/352 13/18639 0.0769230769230769 4.07320804195804 0.219589441523874 0.581831877906322 GO:0019104 DNA N-glycosylase activity 1/352 13/18639 0.0769230769230769 4.07320804195804 0.219589441523874 0.581831877906322 GO:0043560 insulin receptor substrate binding 1/352 13/18639 0.0769230769230769 4.07320804195804 0.219589441523874 0.581831877906322 GO:0070123 transforming growth factor beta receptor activity, type III 1/352 13/18639 0.0769230769230769 4.07320804195804 0.219589441523874 0.581831877906322 GO:0140666 annealing activity 1/352 13/18639 0.0769230769230769 4.07320804195804 0.219589441523874 0.581831877906322 GO:0141003 histone H2AX kinase activity 9/352 354/18639 0.0254237288135593 1.34622977657935 0.227742679891794 0.594358946734715 GO:0016879 ligase activity, forming carbon-nitrogen bonds 2/352 48/18639 0.0416666666666667 2.20632102272727 0.229497907659319 0.594358946734715 GO:0005244 voltage-gated monoatomic ion channel activity 5/352 173/18639 0.0289017341040462 1.53039608512874 0.229522692275927 0.594358946734715 GO:0045182 translation regulator activity 9/352 356/18639 0.0252808988764045 1.33866668794688 0.232486588559007 0.594358946734715 GO:0008191 metalloendopeptidase inhibitor activity 1/352 14/18639 0.0714285714285714 3.78226461038961 0.234337885450836 0.594358946734715 GO:0008195 phosphatidate phosphatase activity 1/352 14/18639 0.0714285714285714 3.78226461038961 0.234337885450836 0.594358946734715 GO:0008331 high voltage-gated calcium channel activity 1/352 14/18639 0.0714285714285714 3.78226461038961 0.234337885450836 0.594358946734715 GO:0042043 neurexin family protein binding 1/352 14/18639 0.0714285714285714 3.78226461038961 0.234337885450836 0.594358946734715 GO:1901474 azole transmembrane transporter activity 1/352 14/18639 0.0714285714285714 3.78226461038961 0.234337885450836 0.594358946734715 GO:1990825 sequence-specific mRNA binding 1/352 14/18639 0.0714285714285714 3.78226461038961 0.234337885450836 0.594358946734715 GO:0140996 histone H3 kinase activity 9/352 357/18639 0.0252100840336134 1.33491692131398 0.234872137913005 0.594358946734715 GO:0005262 calcium channel activity 4/352 131/18639 0.0305343511450382 1.61684594031922 0.235378791253244 0.594358946734715 GO:0022832 voltage-gated channel activity 5/352 175/18639 0.0285714285714286 1.51290584415584 0.23646083120781 0.594358946734715 GO:0005179 hormone activity 4/352 132/18639 0.0303030303030303 1.60459710743802 0.239446004821321 0.594358946734715 GO:0035173 histone kinase activity 9/352 360/18639 0.025 1.32379261363636 0.24208169465545 0.594358946734715 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 3/352 91/18639 0.032967032967033 1.74566058941059 0.246760450257449 0.594358946734715 GO:0005319 lipid transporter activity 5/352 178/18639 0.0280898876404494 1.48740743105209 0.246975453416388 0.594358946734715 GO:0004089 carbonate dehydratase activity 1/352 15/18639 0.0666666666666667 3.53011363636364 0.248808385548624 0.594358946734715 GO:0004129 cytochrome-c oxidase activity 1/352 15/18639 0.0666666666666667 3.53011363636364 0.248808385548624 0.594358946734715 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/352 15/18639 0.0666666666666667 3.53011363636364 0.248808385548624 0.594358946734715 GO:0005523 tropomyosin binding 1/352 15/18639 0.0666666666666667 3.53011363636364 0.248808385548624 0.594358946734715 GO:0008252 nucleotidase activity 1/352 15/18639 0.0666666666666667 3.53011363636364 0.248808385548624 0.594358946734715 GO:0015116 sulfate transmembrane transporter activity 1/352 15/18639 0.0666666666666667 3.53011363636364 0.248808385548624 0.594358946734715 GO:0015929 hexosaminidase activity 1/352 15/18639 0.0666666666666667 3.53011363636364 0.248808385548624 0.594358946734715 GO:0017081 chloride channel regulator activity 1/352 15/18639 0.0666666666666667 3.53011363636364 0.248808385548624 0.594358946734715 GO:0033130 acetylcholine receptor binding 1/352 15/18639 0.0666666666666667 3.53011363636364 0.248808385548624 0.594358946734715 GO:0034483 heparan sulfate sulfotransferase activity 1/352 15/18639 0.0666666666666667 3.53011363636364 0.248808385548624 0.594358946734715 GO:0141050 histone H3K deacetylase activity 1/352 15/18639 0.0666666666666667 3.53011363636364 0.248808385548624 0.594358946734715 GO:0141051 histone H4K deacetylase activity 1/352 15/18639 0.0666666666666667 3.53011363636364 0.248808385548624 0.594358946734715 GO:0042578 phosphoric ester hydrolase activity 9/352 363/18639 0.0247933884297521 1.31285217881292 0.249368005158419 0.594358946734715 GO:0005048 signal sequence binding 2/352 51/18639 0.0392156862745098 2.07653743315508 0.250514927962566 0.594358946734715 GO:0030544 Hsp70 protein binding 2/352 51/18639 0.0392156862745098 2.07653743315508 0.250514927962566 0.594358946734715 GO:0005024 transforming growth factor beta receptor activity 1/352 16/18639 0.0625 3.30948153409091 0.263006165203203 0.601963443223824 GO:0005521 lamin binding 1/352 16/18639 0.0625 3.30948153409091 0.263006165203203 0.601963443223824 GO:0008142 oxysterol binding 1/352 16/18639 0.0625 3.30948153409091 0.263006165203203 0.601963443223824 GO:0015562 efflux transmembrane transporter activity 1/352 16/18639 0.0625 3.30948153409091 0.263006165203203 0.601963443223824 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/352 16/18639 0.0625 3.30948153409091 0.263006165203203 0.601963443223824 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/352 16/18639 0.0625 3.30948153409091 0.263006165203203 0.601963443223824 GO:0019841 retinol binding 1/352 16/18639 0.0625 3.30948153409091 0.263006165203203 0.601963443223824 GO:0022858 alanine transmembrane transporter activity 1/352 16/18639 0.0625 3.30948153409091 0.263006165203203 0.601963443223824 GO:0030275 LRR domain binding 1/352 16/18639 0.0625 3.30948153409091 0.263006165203203 0.601963443223824 GO:0034450 ubiquitin-ubiquitin ligase activity 1/352 16/18639 0.0625 3.30948153409091 0.263006165203203 0.601963443223824 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/352 16/18639 0.0625 3.30948153409091 0.263006165203203 0.601963443223824 GO:0046982 protein heterodimerization activity 9/352 369/18639 0.024390243902439 1.29150498891353 0.264157238283665 0.601963443223824 GO:0008146 sulfotransferase activity 2/352 53/18639 0.0377358490566038 1.99817753001715 0.264558976925344 0.601963443223824 GO:0004867 serine-type endopeptidase inhibitor activity 3/352 95/18639 0.0315789473684211 1.67215909090909 0.267103536952166 0.601963443223824 GO:0140767 enzyme-substrate adaptor activity 4/352 139/18639 0.0287769784172662 1.523790058862 0.268337219968315 0.601963443223824 GO:0008237 metallopeptidase activity 5/352 184/18639 0.0271739130434783 1.43890501482213 0.268350881422176 0.601963443223824 GO:0061135 endopeptidase regulator activity 5/352 184/18639 0.0271739130434783 1.43890501482213 0.268350881422176 0.601963443223824 GO:0015078 proton transmembrane transporter activity 5/352 185/18639 0.027027027027027 1.43112714987715 0.271953566079034 0.601963443223824 GO:0004896 cytokine receptor activity 3/352 96/18639 0.03125 1.65474076704545 0.272221301740695 0.601963443223824 GO:0004549 tRNA-specific ribonuclease activity 1/352 17/18639 0.0588235294117647 3.11480614973262 0.276936349912889 0.601963443223824 GO:0004659 prenyltransferase activity 1/352 17/18639 0.0588235294117647 3.11480614973262 0.276936349912889 0.601963443223824 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/352 17/18639 0.0588235294117647 3.11480614973262 0.276936349912889 0.601963443223824 GO:0005092 GDP-dissociation inhibitor activity 1/352 17/18639 0.0588235294117647 3.11480614973262 0.276936349912889 0.601963443223824 GO:0019198 transmembrane receptor protein phosphatase activity 1/352 17/18639 0.0588235294117647 3.11480614973262 0.276936349912889 0.601963443223824 GO:0030169 low-density lipoprotein particle binding 1/352 17/18639 0.0588235294117647 3.11480614973262 0.276936349912889 0.601963443223824 GO:0048038 quinone binding 1/352 17/18639 0.0588235294117647 3.11480614973262 0.276936349912889 0.601963443223824 GO:0051787 misfolded protein binding 1/352 17/18639 0.0588235294117647 3.11480614973262 0.276936349912889 0.601963443223824 GO:0070402 NADPH binding 1/352 17/18639 0.0588235294117647 3.11480614973262 0.276936349912889 0.601963443223824 GO:0140313 molecular sequestering activity 2/352 55/18639 0.0363636363636364 1.92551652892562 0.278604169158772 0.603780975550054 GO:0005125 cytokine activity 6/352 234/18639 0.0256410256410256 1.35773601398601 0.28172191881048 0.608720574572643 GO:0000400 four-way junction DNA binding 1/352 18/18639 0.0555555555555556 2.94176136363636 0.290603969117629 0.609764397628319 GO:0000900 mRNA regulatory element binding translation repressor activity 1/352 18/18639 0.0555555555555556 2.94176136363636 0.290603969117629 0.609764397628319 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/352 18/18639 0.0555555555555556 2.94176136363636 0.290603969117629 0.609764397628319 GO:0004970 glutamate-gated receptor activity 1/352 18/18639 0.0555555555555556 2.94176136363636 0.290603969117629 0.609764397628319 GO:0008308 voltage-gated monoatomic anion channel activity 1/352 18/18639 0.0555555555555556 2.94176136363636 0.290603969117629 0.609764397628319 GO:0015280 ligand-gated sodium channel activity 1/352 18/18639 0.0555555555555556 2.94176136363636 0.290603969117629 0.609764397628319 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/352 18/18639 0.0555555555555556 2.94176136363636 0.290603969117629 0.609764397628319 GO:0031690 adrenergic receptor binding 1/352 18/18639 0.0555555555555556 2.94176136363636 0.290603969117629 0.609764397628319 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/352 18/18639 0.0555555555555556 2.94176136363636 0.290603969117629 0.609764397628319 GO:1990381 ubiquitin-specific protease binding 1/352 18/18639 0.0555555555555556 2.94176136363636 0.290603969117629 0.609764397628319 GO:0043130 ubiquitin binding 3/352 100/18639 0.03 1.58855113636364 0.292786511604493 0.612573508428998 GO:0061980 regulatory RNA binding 2/352 58/18639 0.0344827586206897 1.82592084639498 0.29963142934923 0.621620121527669 GO:0015085 calcium ion transmembrane transporter activity 4/352 147/18639 0.0272108843537415 1.44086270871985 0.302052712732603 0.621620121527669 GO:0015171 amino acid transmembrane transporter activity 3/352 102/18639 0.0294117647058824 1.55740307486631 0.30311047928116 0.621620121527669 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/352 19/18639 0.0526315789473684 2.78693181818182 0.304013957994198 0.621620121527669 GO:0008301 DNA binding, bending 1/352 19/18639 0.0526315789473684 2.78693181818182 0.304013957994198 0.621620121527669 GO:0016918 retinal binding 1/352 19/18639 0.0526315789473684 2.78693181818182 0.304013957994198 0.621620121527669 GO:0042577 lipid phosphatase activity 1/352 19/18639 0.0526315789473684 2.78693181818182 0.304013957994198 0.621620121527669 GO:0140036 ubiquitin-modified protein reader activity 1/352 19/18639 0.0526315789473684 2.78693181818182 0.304013957994198 0.621620121527669 GO:0015631 tubulin binding 9/352 385/18639 0.0233766233766234 1.23783205430933 0.304816478324862 0.621620121527669 GO:0036002 pre-mRNA binding 2/352 59/18639 0.0338983050847458 1.79497303543914 0.306620682796521 0.621806189134845 GO:0070063 RNA polymerase binding 2/352 59/18639 0.0338983050847458 1.79497303543914 0.306620682796521 0.621806189134845 GO:0098531 ligand-modulated transcription factor activity 2/352 60/18639 0.0333333333333333 1.76505681818182 0.313596510837706 0.631866277189581 GO:0001972 retinoic acid binding 1/352 20/18639 0.05 2.64758522727273 0.317171159217938 0.631866277189581 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/352 20/18639 0.05 2.64758522727273 0.317171159217938 0.631866277189581 GO:0010851 cyclase regulator activity 1/352 20/18639 0.05 2.64758522727273 0.317171159217938 0.631866277189581 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/352 20/18639 0.05 2.64758522727273 0.317171159217938 0.631866277189581 GO:0031418 L-ascorbic acid binding 1/352 20/18639 0.05 2.64758522727273 0.317171159217938 0.631866277189581 GO:0140297 DNA-binding transcription factor binding 11/352 488/18639 0.0225409836065574 1.19358350409836 0.317673817044349 0.631866277189581 GO:0042393 histone binding 6/352 247/18639 0.0242914979757085 1.28627622377622 0.324439976831374 0.63903550860306 GO:0016829 lyase activity 5/352 200/18639 0.025 1.32379261363636 0.32701522093122 0.63903550860306 GO:0015179 L-amino acid transmembrane transporter activity 2/352 62/18639 0.032258064516129 1.70811950146628 0.327500043791742 0.63903550860306 GO:0019888 protein phosphatase regulator activity 3/352 107/18639 0.0280373831775701 1.48462723024639 0.328975062135454 0.63903550860306 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/352 21/18639 0.0476190476190476 2.52150974025974 0.330080324691663 0.63903550860306 GO:0008373 sialyltransferase activity 1/352 21/18639 0.0476190476190476 2.52150974025974 0.330080324691663 0.63903550860306 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/352 21/18639 0.0476190476190476 2.52150974025974 0.330080324691663 0.63903550860306 GO:0036122 BMP binding 1/352 21/18639 0.0476190476190476 2.52150974025974 0.330080324691663 0.63903550860306 GO:0051010 microtubule plus-end binding 1/352 21/18639 0.0476190476190476 2.52150974025974 0.330080324691663 0.63903550860306 GO:0051428 peptide hormone receptor binding 1/352 21/18639 0.0476190476190476 2.52150974025974 0.330080324691663 0.63903550860306 GO:0140104 molecular carrier activity 6/352 249/18639 0.0240963855421687 1.27594468784228 0.331100019850909 0.639304825563191 GO:0005507 copper ion binding 2/352 63/18639 0.0317460317460317 1.68100649350649 0.334424020979037 0.644010183636024 GO:0004536 DNA nuclease activity 2/352 64/18639 0.03125 1.65474076704545 0.341327112826291 0.651397070989372 GO:0004407 histone deacetylase activity 1/352 22/18639 0.0454545454545455 2.40689566115702 0.342746117242341 0.651397070989372 GO:0005243 gap junction channel activity 1/352 22/18639 0.0454545454545455 2.40689566115702 0.342746117242341 0.651397070989372 GO:0033558 protein lysine deacetylase activity 1/352 22/18639 0.0454545454545455 2.40689566115702 0.342746117242341 0.651397070989372 GO:0140035 ubiquitin-like protein reader activity 1/352 22/18639 0.0454545454545455 2.40689566115702 0.342746117242341 0.651397070989372 GO:0004222 metalloendopeptidase activity 3/352 110/18639 0.0272727272727273 1.44413739669421 0.344492639063996 0.653006934622613 GO:0160215 deacylase activity 2/352 65/18639 0.0307692307692308 1.62928321678322 0.348207641212403 0.6583300716672 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/352 23/18639 0.0434782608695652 2.30224802371541 0.355173112286156 0.659477441226981 GO:0005158 insulin receptor binding 1/352 23/18639 0.0434782608695652 2.30224802371541 0.355173112286156 0.659477441226981 GO:0005212 structural constituent of eye lens 1/352 23/18639 0.0434782608695652 2.30224802371541 0.355173112286156 0.659477441226981 GO:0008171 O-methyltransferase activity 1/352 23/18639 0.0434782608695652 2.30224802371541 0.355173112286156 0.659477441226981 GO:0031681 G-protein beta-subunit binding 1/352 23/18639 0.0434782608695652 2.30224802371541 0.355173112286156 0.659477441226981 GO:0042171 lysophosphatidic acid acyltransferase activity 1/352 23/18639 0.0434782608695652 2.30224802371541 0.355173112286156 0.659477441226981 GO:0071617 lysophospholipid acyltransferase activity 1/352 23/18639 0.0434782608695652 2.30224802371541 0.355173112286156 0.659477441226981 GO:0004175 endopeptidase activity 9/352 405/18639 0.0222222222222222 1.17670454545455 0.357466023867238 0.662041666652079 GO:0051015 actin filament binding 5/352 209/18639 0.0239234449760766 1.26678719008264 0.360621122982262 0.662561453311543 GO:0050840 extracellular matrix binding 2/352 67/18639 0.0298507462686567 1.58064789687924 0.361894645353131 0.662561453311543 GO:0022804 active transmembrane transporter activity 10/352 457/18639 0.0218818380743982 1.15868062462701 0.362920782277242 0.662561453311543 GO:0015149 hexose transmembrane transporter activity 1/352 24/18639 0.0416666666666667 2.20632102272727 0.367365799462524 0.662561453311543 GO:0015295 solute:proton symporter activity 1/352 24/18639 0.0416666666666667 2.20632102272727 0.367365799462524 0.662561453311543 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/352 24/18639 0.0416666666666667 2.20632102272727 0.367365799462524 0.662561453311543 GO:0030215 semaphorin receptor binding 1/352 24/18639 0.0416666666666667 2.20632102272727 0.367365799462524 0.662561453311543 GO:0030552 cAMP binding 1/352 24/18639 0.0416666666666667 2.20632102272727 0.367365799462524 0.662561453311543 GO:0055056 D-glucose transmembrane transporter activity 1/352 24/18639 0.0416666666666667 2.20632102272727 0.367365799462524 0.662561453311543 GO:0070840 dynein complex binding 1/352 24/18639 0.0416666666666667 2.20632102272727 0.367365799462524 0.662561453311543 GO:0005548 phospholipid transporter activity 2/352 68/18639 0.0294117647058824 1.55740307486631 0.368698109005322 0.662561453311543 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 2/352 68/18639 0.0294117647058824 1.55740307486631 0.368698109005322 0.662561453311543 GO:0001221 transcription coregulator binding 3/352 115/18639 0.0260869565217391 1.38134881422925 0.370275326085658 0.663752806760958 GO:0005251 delayed rectifier potassium channel activity 1/352 25/18639 0.04 2.11806818181818 0.379328584237662 0.665199401344306 GO:0005537 D-mannose binding 1/352 25/18639 0.04 2.11806818181818 0.379328584237662 0.665199401344306 GO:0015645 fatty acid ligase activity 1/352 25/18639 0.04 2.11806818181818 0.379328584237662 0.665199401344306 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/352 25/18639 0.04 2.11806818181818 0.379328584237662 0.665199401344306 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/352 25/18639 0.04 2.11806818181818 0.379328584237662 0.665199401344306 GO:0019707 protein-cysteine S-acyltransferase activity 1/352 25/18639 0.04 2.11806818181818 0.379328584237662 0.665199401344306 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/352 25/18639 0.04 2.11806818181818 0.379328584237662 0.665199401344306 GO:0120020 cholesterol transfer activity 1/352 25/18639 0.04 2.11806818181818 0.379328584237662 0.665199401344306 GO:0120515 fatty acid-CoA ligase activity 1/352 25/18639 0.04 2.11806818181818 0.379328584237662 0.665199401344306 GO:0019208 phosphatase regulator activity 3/352 117/18639 0.0256410256410256 1.35773601398601 0.380540972053115 0.665717459543522 GO:0016782 transferase activity, transferring sulphur-containing groups 2/352 70/18639 0.0285714285714286 1.51290584415584 0.382217915661278 0.667043766274249 GO:0016874 ligase activity 4/352 167/18639 0.0239520958083832 1.26830430048993 0.387643633946146 0.671190929459128 GO:0004435 phosphatidylinositol phospholipase C activity 1/352 26/18639 0.0384615384615385 2.03660402097902 0.391065789478252 0.671190929459128 GO:0005112 Notch binding 1/352 26/18639 0.0384615384615385 2.03660402097902 0.391065789478252 0.671190929459128 GO:0005160 transforming growth factor beta receptor binding 1/352 26/18639 0.0384615384615385 2.03660402097902 0.391065789478252 0.671190929459128 GO:0008066 glutamate receptor activity 1/352 26/18639 0.0384615384615385 2.03660402097902 0.391065789478252 0.671190929459128 GO:0015145 monosaccharide transmembrane transporter activity 1/352 26/18639 0.0384615384615385 2.03660402097902 0.391065789478252 0.671190929459128 GO:0043548 phosphatidylinositol 3-kinase binding 1/352 26/18639 0.0384615384615385 2.03660402097902 0.391065789478252 0.671190929459128 GO:0032182 ubiquitin-like protein binding 3/352 120/18639 0.025 1.32379261363636 0.395869205463015 0.673443048338555 GO:0004521 RNA endonuclease activity 2/352 73/18639 0.0273972602739726 1.45073163138232 0.402260536755171 0.673443048338555 GO:0004364 glutathione transferase activity 1/352 27/18639 0.037037037037037 1.96117424242424 0.402581656995775 0.673443048338555 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/352 27/18639 0.037037037037037 1.96117424242424 0.402581656995775 0.673443048338555 GO:0005044 scavenger receptor activity 1/352 27/18639 0.037037037037037 1.96117424242424 0.402581656995775 0.673443048338555 GO:0005104 fibroblast growth factor receptor binding 1/352 27/18639 0.037037037037037 1.96117424242424 0.402581656995775 0.673443048338555 GO:0008266 poly(U) RNA binding 1/352 27/18639 0.037037037037037 1.96117424242424 0.402581656995775 0.673443048338555 GO:0008320 protein transmembrane transporter activity 1/352 27/18639 0.037037037037037 1.96117424242424 0.402581656995775 0.673443048338555 GO:0015252 proton channel activity 1/352 27/18639 0.037037037037037 1.96117424242424 0.402581656995775 0.673443048338555 GO:0016405 CoA-ligase activity 1/352 27/18639 0.037037037037037 1.96117424242424 0.402581656995775 0.673443048338555 GO:0035255 ionotropic glutamate receptor binding 1/352 27/18639 0.037037037037037 1.96117424242424 0.402581656995775 0.673443048338555 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 3/352 122/18639 0.0245901639344262 1.30209109538003 0.406032744223972 0.677654648980698 GO:0050698 proteoglycan sulfotransferase activity 1/352 28/18639 0.0357142857142857 1.89113230519481 0.413880349062049 0.684895305483345 GO:0051119 sugar transmembrane transporter activity 1/352 28/18639 0.0357142857142857 1.89113230519481 0.413880349062049 0.684895305483345 GO:0051537 2 iron, 2 sulfur cluster binding 1/352 28/18639 0.0357142857142857 1.89113230519481 0.413880349062049 0.684895305483345 GO:0005267 potassium channel activity 3/352 124/18639 0.0241935483870968 1.28108962609971 0.41614564325848 0.684895305483345 GO:0017022 myosin binding 2/352 76/18639 0.0263157894736842 1.39346590909091 0.421990898731127 0.684895305483345 GO:0051536 iron-sulfur cluster binding 2/352 76/18639 0.0263157894736842 1.39346590909091 0.421990898731127 0.684895305483345 GO:0004181 metallocarboxypeptidase activity 1/352 29/18639 0.0344827586206897 1.82592084639498 0.42496594989651 0.684895305483345 GO:0004629 phospholipase C activity 1/352 29/18639 0.0344827586206897 1.82592084639498 0.42496594989651 0.684895305483345 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/352 29/18639 0.0344827586206897 1.82592084639498 0.42496594989651 0.684895305483345 GO:0016417 S-acyltransferase activity 1/352 29/18639 0.0344827586206897 1.82592084639498 0.42496594989651 0.684895305483345 GO:0043236 laminin binding 1/352 29/18639 0.0344827586206897 1.82592084639498 0.42496594989651 0.684895305483345 GO:0097472 cyclin-dependent protein kinase activity 1/352 29/18639 0.0344827586206897 1.82592084639498 0.42496594989651 0.684895305483345 GO:0099604 ligand-gated calcium channel activity 1/352 29/18639 0.0344827586206897 1.82592084639498 0.42496594989651 0.684895305483345 GO:0106222 lncRNA binding 1/352 29/18639 0.0344827586206897 1.82592084639498 0.42496594989651 0.684895305483345 GO:0004252 serine-type endopeptidase activity 4/352 176/18639 0.0227272727272727 1.20344783057851 0.425908717111851 0.684895305483345 GO:0003724 RNA helicase activity 2/352 77/18639 0.025974025974026 1.37536894923259 0.428493467371275 0.684895305483345 GO:0051540 metal cluster binding 2/352 77/18639 0.025974025974026 1.37536894923259 0.428493467371275 0.684895305483345 GO:0001217 DNA-binding transcription repressor activity 6/352 278/18639 0.0215827338129496 1.1428425441465 0.428545580775738 0.684895305483345 GO:0042826 histone deacetylase binding 3/352 127/18639 0.0236220472440945 1.25082766642806 0.431208744032392 0.684895305483345 GO:0030246 carbohydrate binding 6/352 280/18639 0.0214285714285714 1.13467938311688 0.43524109202754 0.684895305483345 GO:0001965 G-protein alpha-subunit binding 1/352 30/18639 0.0333333333333333 1.76505681818182 0.435842467125765 0.684895305483345 GO:0008187 poly-pyrimidine tract binding 1/352 30/18639 0.0333333333333333 1.76505681818182 0.435842467125765 0.684895305483345 GO:0016769 transferase activity, transferring nitrogenous groups 1/352 30/18639 0.0333333333333333 1.76505681818182 0.435842467125765 0.684895305483345 GO:0031210 phosphatidylcholine binding 1/352 30/18639 0.0333333333333333 1.76505681818182 0.435842467125765 0.684895305483345 GO:0048019 receptor antagonist activity 1/352 30/18639 0.0333333333333333 1.76505681818182 0.435842467125765 0.684895305483345 GO:0051721 protein phosphatase 2A binding 1/352 30/18639 0.0333333333333333 1.76505681818182 0.435842467125765 0.684895305483345 GO:0070566 adenylyltransferase activity 1/352 30/18639 0.0333333333333333 1.76505681818182 0.435842467125765 0.684895305483345 GO:0008186 ATP-dependent activity, acting on RNA 2/352 79/18639 0.0253164556962025 1.34054948216341 0.441381752630629 0.689751177533443 GO:0005184 neuropeptide hormone activity 1/352 31/18639 0.032258064516129 1.70811950146628 0.446513833215922 0.689751177533443 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/352 31/18639 0.032258064516129 1.70811950146628 0.446513833215922 0.689751177533443 GO:0005452 solute:inorganic anion antiporter activity 1/352 31/18639 0.032258064516129 1.70811950146628 0.446513833215922 0.689751177533443 GO:0016411 acylglycerol O-acyltransferase activity 1/352 31/18639 0.032258064516129 1.70811950146628 0.446513833215922 0.689751177533443 GO:0016878 acid-thiol ligase activity 1/352 31/18639 0.032258064516129 1.70811950146628 0.446513833215922 0.689751177533443 GO:0072349 modified amino acid transmembrane transporter activity 1/352 31/18639 0.032258064516129 1.70811950146628 0.446513833215922 0.689751177533443 GO:0000049 tRNA binding 2/352 80/18639 0.025 1.32379261363636 0.447765794330149 0.689751177533443 GO:0048306 calcium-dependent protein binding 2/352 80/18639 0.025 1.32379261363636 0.447765794330149 0.689751177533443 GO:0030971 receptor tyrosine kinase binding 2/352 81/18639 0.0246913580246914 1.30744949494949 0.454108727489962 0.689751177533443 GO:0015106 bicarbonate transmembrane transporter activity 1/352 32/18639 0.03125 1.65474076704545 0.456983906878217 0.689751177533443 GO:0022884 macromolecule transmembrane transporter activity 1/352 32/18639 0.03125 1.65474076704545 0.456983906878217 0.689751177533443 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/352 32/18639 0.03125 1.65474076704545 0.456983906878217 0.689751177533443 GO:0043425 bHLH transcription factor binding 1/352 32/18639 0.03125 1.65474076704545 0.456983906878217 0.689751177533443 GO:0051059 NF-kappaB binding 1/352 32/18639 0.03125 1.65474076704545 0.456983906878217 0.689751177533443 GO:0071813 lipoprotein particle binding 1/352 32/18639 0.03125 1.65474076704545 0.456983906878217 0.689751177533443 GO:0071814 protein-lipid complex binding 1/352 32/18639 0.03125 1.65474076704545 0.456983906878217 0.689751177533443 GO:0120015 sterol transfer activity 1/352 32/18639 0.03125 1.65474076704545 0.456983906878217 0.689751177533443 GO:0160041 neuropeptide activity 1/352 32/18639 0.03125 1.65474076704545 0.456983906878217 0.689751177533443 GO:0003779 actin binding 9/352 443/18639 0.0203160270880361 1.07576826390314 0.459480643613889 0.692080803451625 GO:0005261 monoatomic cation channel activity 7/352 341/18639 0.0205278592375367 1.08698513729672 0.46526075661308 0.693718201328338 GO:0001540 amyloid-beta binding 2/352 83/18639 0.0240963855421687 1.27594468784228 0.466668404022767 0.693718201328338 GO:0030165 PDZ domain binding 2/352 83/18639 0.0240963855421687 1.27594468784228 0.466668404022767 0.693718201328338 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/352 33/18639 0.0303030303030303 1.60459710743802 0.467256474448426 0.693718201328338 GO:0030296 protein tyrosine kinase activator activity 1/352 33/18639 0.0303030303030303 1.60459710743802 0.467256474448426 0.693718201328338 GO:0042923 neuropeptide binding 1/352 33/18639 0.0303030303030303 1.60459710743802 0.467256474448426 0.693718201328338 GO:0140311 protein sequestering activity 1/352 33/18639 0.0303030303030303 1.60459710743802 0.467256474448426 0.693718201328338 GO:0004842 ubiquitin-protein transferase activity 9/352 449/18639 0.0200445434298441 1.06139274144564 0.475471096245669 0.697274431389608 GO:0044325 transmembrane transporter binding 3/352 136/18639 0.0220588235294118 1.16805230614973 0.475486527969795 0.697274431389608 GO:0046943 carboxylic acid transmembrane transporter activity 4/352 188/18639 0.0212765957446809 1.12663201160542 0.475909430106408 0.697274431389608 GO:0140597 protein carrier chaperone 4/352 188/18639 0.0212765957446809 1.12663201160542 0.475909430106408 0.697274431389608 GO:0008175 tRNA methyltransferase activity 1/352 34/18639 0.0294117647058824 1.55740307486631 0.477335251240544 0.697274431389608 GO:0030332 cyclin binding 1/352 34/18639 0.0294117647058824 1.55740307486631 0.477335251240544 0.697274431389608 GO:0051427 hormone receptor binding 1/352 34/18639 0.0294117647058824 1.55740307486631 0.477335251240544 0.697274431389608 GO:0090482 vitamin transmembrane transporter activity 1/352 34/18639 0.0294117647058824 1.55740307486631 0.477335251240544 0.697274431389608 GO:0005342 organic acid transmembrane transporter activity 4/352 189/18639 0.0211640211640212 1.120670995671 0.480005546681361 0.699767122270418 GO:0016229 steroid dehydrogenase activity 1/352 35/18639 0.0285714285714286 1.51290584415584 0.48722388287523 0.707449077934834 GO:0034061 DNA polymerase activity 1/352 35/18639 0.0285714285714286 1.51290584415584 0.48722388287523 0.707449077934834 GO:0140101 catalytic activity, acting on a tRNA 3/352 139/18639 0.0215827338129496 1.1428425441465 0.489895512023233 0.709908466524685 GO:0004190 aspartic-type endopeptidase activity 1/352 36/18639 0.0277777777777778 1.47088068181818 0.49692594658346 0.713520706265958 GO:0005484 SNAP receptor activity 1/352 36/18639 0.0277777777777778 1.47088068181818 0.49692594658346 0.713520706265958 GO:0016409 palmitoyltransferase activity 1/352 36/18639 0.0277777777777778 1.47088068181818 0.49692594658346 0.713520706265958 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/352 36/18639 0.0277777777777778 1.47088068181818 0.49692594658346 0.713520706265958 GO:0004197 cysteine-type endopeptidase activity 2/352 88/18639 0.0227272727272727 1.20344783057851 0.497302310427789 0.713520706265958 GO:0008236 serine-type peptidase activity 4/352 194/18639 0.0206185567010309 1.09178772258669 0.500293393173787 0.716396456497376 GO:0061630 ubiquitin protein ligase activity 7/352 353/18639 0.0198300283286119 1.05003380118465 0.501461982252586 0.716656297471216 GO:0030551 cyclic nucleotide binding 1/352 37/18639 0.027027027027027 1.43112714987715 0.506444952485875 0.720939285303422 GO:0070001 aspartic-type peptidase activity 1/352 37/18639 0.027027027027027 1.43112714987715 0.506444952485875 0.720939285303422 GO:0022843 voltage-gated monoatomic cation channel activity 3/352 143/18639 0.020979020979021 1.11087492053401 0.508801732908346 0.722876826010683 GO:0019903 protein phosphatase binding 3/352 144/18639 0.0208333333333333 1.10316051136364 0.513471108607441 0.724981601881207 GO:0072341 modified amino acid binding 2/352 91/18639 0.021978021978022 1.16377372627373 0.515136989011659 0.724981601881207 GO:0005109 frizzled binding 1/352 38/18639 0.0263157894736842 1.39346590909091 0.515784344848254 0.724981601881207 GO:0042162 telomeric DNA binding 1/352 38/18639 0.0263157894736842 1.39346590909091 0.515784344848254 0.724981601881207 GO:0043531 ADP binding 1/352 38/18639 0.0263157894736842 1.39346590909091 0.515784344848254 0.724981601881207 GO:0017171 serine hydrolase activity 4/352 198/18639 0.0202020202020202 1.06973140495868 0.516274777097223 0.724981601881207 GO:0000217 DNA secondary structure binding 1/352 39/18639 0.0256410256410256 1.35773601398601 0.524947503313574 0.735737234373851 GO:0051213 dioxygenase activity 2/352 93/18639 0.021505376344086 1.13874633431085 0.526792423381561 0.736900384152241 GO:0015144 carbohydrate transmembrane transporter activity 1/352 40/18639 0.025 1.32379261363636 0.53393774411108 0.741183178249798 GO:0050997 quaternary ammonium group binding 1/352 40/18639 0.025 1.32379261363636 0.53393774411108 0.741183178249798 GO:0071855 neuropeptide receptor binding 1/352 40/18639 0.025 1.32379261363636 0.53393774411108 0.741183178249798 GO:0140662 ATP-dependent protein folding chaperone 1/352 40/18639 0.025 1.32379261363636 0.53393774411108 0.741183178249798 GO:0019842 vitamin binding 3/352 150/18639 0.02 1.05903409090909 0.5409807790562 0.745795406181778 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/352 41/18639 0.024390243902439 1.29150498891353 0.542758321242802 0.745795406181778 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/352 41/18639 0.024390243902439 1.29150498891353 0.542758321242802 0.745795406181778 GO:0140318 protein transporter activity 1/352 41/18639 0.024390243902439 1.29150498891353 0.542758321242802 0.745795406181778 GO:0000510 H3-H4 histone complex chaperone activity 3/352 151/18639 0.0198675496688742 1.05202062010837 0.545478458240391 0.745795406181778 GO:0140584 chromatin extrusion motor activity 3/352 151/18639 0.0198675496688742 1.05202062010837 0.545478458240391 0.745795406181778 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 3/352 151/18639 0.0198675496688742 1.05202062010837 0.545478458240391 0.745795406181778 GO:0140849 ATP-dependent H2AZ histone chaperone activity 3/352 151/18639 0.0198675496688742 1.05202062010837 0.545478458240391 0.745795406181778 GO:0051020 GTPase binding 6/352 315/18639 0.019047619047619 1.0086038961039 0.54882819393805 0.746287922269008 GO:0030594 neurotransmitter receptor activity 2/352 97/18639 0.0206185567010309 1.09178772258669 0.549529638720511 0.746287922269008 GO:0015616 DNA translocase activity 3/352 152/18639 0.0197368421052632 1.04509943181818 0.549950466134875 0.746287922269008 GO:0140674 ATP-dependent histone chaperone activity 3/352 152/18639 0.0197368421052632 1.04509943181818 0.549950466134875 0.746287922269008 GO:0031492 nucleosomal DNA binding 1/352 42/18639 0.0238095238095238 1.26075487012987 0.551412427647929 0.746875788194769 GO:0019787 ubiquitin-like protein transferase activity 9/352 479/18639 0.0187891440501044 0.994917204403112 0.553470849787398 0.747676314481948 GO:0061775 cohesin loader activity 3/352 153/18639 0.0196078431372549 1.03826871657754 0.554396552010319 0.747676314481948 GO:0005249 voltage-gated potassium channel activity 2/352 98/18639 0.0204081632653061 1.08064703153989 0.55509302135781 0.747676314481948 GO:0061659 ubiquitin-like protein ligase activity 7/352 372/18639 0.0188172043010753 0.996403042521994 0.557022466623191 0.748599853677351 GO:0022836 gated channel activity 6/352 318/18639 0.0188679245283019 0.999088765008576 0.558115443177906 0.748599853677351 GO:0004518 nuclease activity 4/352 209/18639 0.0191387559808612 1.01342975206612 0.558940369786366 0.748599853677351 GO:0005245 voltage-gated calcium channel activity 1/352 43/18639 0.0232558139534884 1.23143498942918 0.559903196345457 0.748599853677351 GO:0140375 immune receptor activity 3/352 156/18639 0.0192307692307692 1.01830201048951 0.567576937176572 0.752805962279763 GO:0001046 core promoter sequence-specific DNA binding 1/352 44/18639 0.0227272727272727 1.20344783057851 0.568233701555523 0.752805962279763 GO:0001223 transcription coactivator binding 1/352 44/18639 0.0227272727272727 1.20344783057851 0.568233701555523 0.752805962279763 GO:0030547 signaling receptor inhibitor activity 1/352 44/18639 0.0227272727272727 1.20344783057851 0.568233701555523 0.752805962279763 GO:0043014 alpha-tubulin binding 1/352 44/18639 0.0227272727272727 1.20344783057851 0.568233701555523 0.752805962279763 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 5/352 268/18639 0.0186567164179104 0.987904935549525 0.573257627632074 0.757321323112967 GO:0140658 ATP-dependent chromatin remodeler activity 3/352 158/18639 0.0189873417721519 1.00541211162255 0.576230149279273 0.757321323112967 GO:0046915 transition metal ion transmembrane transporter activity 1/352 45/18639 0.0222222222222222 1.17670454545455 0.576406959799807 0.757321323112967 GO:0008514 organic anion transmembrane transporter activity 5/352 269/18639 0.0185873605947955 0.984232426495438 0.576571278249535 0.757321323112967 GO:0008238 exopeptidase activity 2/352 102/18639 0.0196078431372549 1.03826871657754 0.576857702040593 0.757321323112967 GO:0004180 carboxypeptidase activity 1/352 46/18639 0.0217391304347826 1.15112401185771 0.584425930981396 0.762201697180186 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/352 46/18639 0.0217391304347826 1.15112401185771 0.584425930981396 0.762201697180186 GO:0003689 DNA clamp loader activity 3/352 160/18639 0.01875 0.992844460227273 0.584774580343476 0.762201697180186 GO:0015079 potassium ion transmembrane transporter activity 3/352 160/18639 0.01875 0.992844460227273 0.584774580343476 0.762201697180186 GO:0016791 phosphatase activity 5/352 273/18639 0.0183150183150183 0.969811438561439 0.589689371734942 0.76649749575171 GO:0005504 fatty acid binding 1/352 47/18639 0.0212765957446809 1.12663201160542 0.592293519444503 0.76649749575171 GO:0043495 protein-membrane adaptor activity 1/352 47/18639 0.0212765957446809 1.12663201160542 0.592293519444503 0.76649749575171 GO:0140359 ABC-type transporter activity 1/352 47/18639 0.0212765957446809 1.12663201160542 0.592293519444503 0.76649749575171 GO:0016755 aminoacyltransferase activity 9/352 496/18639 0.0181451612903226 0.96081721957478 0.595581948600126 0.768270069595159 GO:0005543 phospholipid binding 9/352 497/18639 0.0181086519114688 0.958883985732577 0.598000706277001 0.768270069595159 GO:0008017 microtubule binding 5/352 276/18639 0.0181159420289855 0.959270009881423 0.599381103519374 0.768270069595159 GO:0008188 neuropeptide receptor activity 1/352 48/18639 0.0208333333333333 1.10316051136364 0.600012575014401 0.768270069595159 GO:0038187 pattern recognition receptor activity 1/352 48/18639 0.0208333333333333 1.10316051136364 0.600012575014401 0.768270069595159 GO:0140693 molecular condensate scaffold activity 1/352 48/18639 0.0208333333333333 1.10316051136364 0.600012575014401 0.768270069595159 GO:0140713 histone chaperone activity 3/352 164/18639 0.0182926829268293 0.968628741685144 0.601531769082983 0.768859268229306 GO:0001222 transcription corepressor binding 1/352 49/18639 0.0204081632653061 1.08064703153989 0.607585894017947 0.772517266299526 GO:0035254 glutamate receptor binding 1/352 49/18639 0.0204081632653061 1.08064703153989 0.607585894017947 0.772517266299526 GO:0060590 ATPase regulator activity 1/352 49/18639 0.0204081632653061 1.08064703153989 0.607585894017947 0.772517266299526 GO:0140097 catalytic activity, acting on DNA 6/352 336/18639 0.0178571428571429 0.945566152597403 0.611856348345543 0.776586903669343 GO:0005216 monoatomic ion channel activity 8/352 448/18639 0.0178571428571429 0.945566152597403 0.613405357182849 0.777194222189788 GO:0046873 metal ion transmembrane transporter activity 8/352 450/18639 0.0177777777777778 0.941363636363636 0.618401332638451 0.782159176821455 GO:0031267 small GTPase binding 5/352 283/18639 0.0176678445229682 0.935542483135239 0.621487301959495 0.783005779361314 GO:0005272 sodium channel activity 1/352 51/18639 0.0196078431372549 1.03826871657754 0.622306246131513 0.783005779361314 GO:0016597 amino acid binding 1/352 51/18639 0.0196078431372549 1.03826871657754 0.622306246131513 0.783005779361314 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/352 52/18639 0.0192307692307692 1.01830201048951 0.629458613323341 0.790634867253885 GO:0005246 calcium channel regulator activity 1/352 53/18639 0.0188679245283019 0.999088765008576 0.636475914023303 0.795321021653903 GO:0051018 protein kinase A binding 1/352 53/18639 0.0188679245283019 0.999088765008576 0.636475914023303 0.795321021653903 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/352 53/18639 0.0188679245283019 0.999088765008576 0.636475914023303 0.795321021653903 GO:0003925 G protein activity 1/352 54/18639 0.0185185185185185 0.980587121212121 0.643360691719622 0.798427114852044 GO:0017069 snRNA binding 1/352 54/18639 0.0185185185185185 0.980587121212121 0.643360691719622 0.798427114852044 GO:0050661 NADP binding 1/352 54/18639 0.0185185185185185 0.980587121212121 0.643360691719622 0.798427114852044 GO:0140463 chromatin-protein adaptor activity 1/352 54/18639 0.0185185185185185 0.980587121212121 0.643360691719622 0.798427114852044 GO:0015294 solute:monoatomic cation symporter activity 2/352 116/18639 0.0172413793103448 0.912960423197492 0.646834672365178 0.801368553135016 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 6/352 349/18639 0.0171919770773639 0.9103444907528 0.648328791693237 0.801851282400835 GO:0008374 O-acyltransferase activity 1/352 55/18639 0.0181818181818182 0.96275826446281 0.650115442137416 0.802693556108442 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/352 56/18639 0.0178571428571429 0.945566152597403 0.656742614133091 0.804834959842605 GO:0016853 isomerase activity 3/352 180/18639 0.0166666666666667 0.882528409090909 0.66400637508769 0.804834959842605 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 3/352 181/18639 0.0165745856353591 0.877652561526871 0.667665202430575 0.804834959842605 GO:0004540 RNA nuclease activity 2/352 121/18639 0.0165289256198347 0.875234785875282 0.669508951905294 0.804834959842605 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/352 122/18639 0.0163934426229508 0.868060730253353 0.673900222033316 0.804834959842605 GO:0004879 nuclear receptor activity 1/352 59/18639 0.0169491525423729 0.897486517719569 0.675882463438156 0.804834959842605 GO:0031593 polyubiquitin modification-dependent protein binding 1/352 59/18639 0.0169491525423729 0.897486517719569 0.675882463438156 0.804834959842605 GO:0070888 E-box binding 1/352 59/18639 0.0169491525423729 0.897486517719569 0.675882463438156 0.804834959842605 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 4/352 243/18639 0.0164609053497942 0.871632996632997 0.676690761794283 0.804834959842605 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/352 60/18639 0.0166666666666667 0.882528409090909 0.68202290331274 0.804834959842605 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/352 60/18639 0.0166666666666667 0.882528409090909 0.68202290331274 0.804834959842605 GO:0004676 3-phosphoinositide-dependent protein kinase activity 4/352 245/18639 0.0163265306122449 0.864517625231911 0.682890268957362 0.804834959842605 GO:0004711 ribosomal protein S6 kinase activity 4/352 245/18639 0.0163265306122449 0.864517625231911 0.682890268957362 0.804834959842605 GO:0035175 histone H3S10 kinase activity 4/352 245/18639 0.0163265306122449 0.864517625231911 0.682890268957362 0.804834959842605 GO:0035979 histone H2AXS139 kinase activity 4/352 245/18639 0.0163265306122449 0.864517625231911 0.682890268957362 0.804834959842605 GO:0044022 histone H3S28 kinase activity 4/352 245/18639 0.0163265306122449 0.864517625231911 0.682890268957362 0.804834959842605 GO:0044023 histone H4S1 kinase activity 4/352 245/18639 0.0163265306122449 0.864517625231911 0.682890268957362 0.804834959842605 GO:0044024 histone H2AS1 kinase activity 4/352 245/18639 0.0163265306122449 0.864517625231911 0.682890268957362 0.804834959842605 GO:0044025 histone H2BS14 kinase activity 4/352 245/18639 0.0163265306122449 0.864517625231911 0.682890268957362 0.804834959842605 GO:0072354 histone H3T3 kinase activity 4/352 245/18639 0.0163265306122449 0.864517625231911 0.682890268957362 0.804834959842605 GO:0072371 histone H2AS121 kinase activity 4/352 245/18639 0.0163265306122449 0.864517625231911 0.682890268957362 0.804834959842605 GO:0072518 Rho-dependent protein serine/threonine kinase activity 4/352 245/18639 0.0163265306122449 0.864517625231911 0.682890268957362 0.804834959842605 GO:0140823 histone H2BS36 kinase activity 4/352 245/18639 0.0163265306122449 0.864517625231911 0.682890268957362 0.804834959842605 GO:0140855 histone H3S57 kinase activity 4/352 245/18639 0.0163265306122449 0.864517625231911 0.682890268957362 0.804834959842605 GO:0140995 histone H2A kinase activity 4/352 245/18639 0.0163265306122449 0.864517625231911 0.682890268957362 0.804834959842605 GO:0140997 histone H4 kinase activity 4/352 245/18639 0.0163265306122449 0.864517625231911 0.682890268957362 0.804834959842605 GO:0140998 histone H2B kinase activity 4/352 245/18639 0.0163265306122449 0.864517625231911 0.682890268957362 0.804834959842605 GO:1990244 histone H2AT120 kinase activity 4/352 245/18639 0.0163265306122449 0.864517625231911 0.682890268957362 0.804834959842605 GO:0004677 DNA-dependent protein kinase activity 4/352 246/18639 0.016260162601626 0.861003325942351 0.685958720062105 0.805504927200929 GO:0140857 histone H3T45 kinase activity 4/352 246/18639 0.016260162601626 0.861003325942351 0.685958720062105 0.805504927200929 GO:0019905 syntaxin binding 1/352 61/18639 0.0163934426229508 0.868060730253353 0.688047336168864 0.805504927200929 GO:0035402 histone H3T11 kinase activity 4/352 247/18639 0.0161943319838057 0.857517482517483 0.689006280704927 0.805504927200929 GO:0035403 histone H3T6 kinase activity 4/352 247/18639 0.0161943319838057 0.857517482517483 0.689006280704927 0.805504927200929 GO:0004679 AMP-activated protein kinase activity 4/352 248/18639 0.0161290322580645 0.854059750733138 0.69203293865739 0.807742626149944 GO:0019902 phosphatase binding 3/352 190/18639 0.0157894736842105 0.836079545454545 0.699288344872487 0.81283759392019 GO:0022824 transmitter-gated monoatomic ion channel activity 1/352 63/18639 0.0158730158730159 0.840503246753247 0.699756881818345 0.81283759392019 GO:0022835 transmitter-gated channel activity 1/352 63/18639 0.0158730158730159 0.840503246753247 0.699756881818345 0.81283759392019 GO:0035591 signaling adaptor activity 2/352 129/18639 0.0155038759689922 0.82095665961945 0.703324830453981 0.815677039791677 GO:0016298 lipase activity 2/352 130/18639 0.0153846153846154 0.814641608391608 0.70734350239915 0.819029318567437 GO:0038024 cargo receptor activity 1/352 65/18639 0.0153846153846154 0.814641608391608 0.711028096387457 0.820677898215093 GO:0120013 lipid transfer activity 1/352 65/18639 0.0153846153846154 0.814641608391608 0.711028096387457 0.820677898215093 GO:0004674 protein serine/threonine kinase activity 7/352 433/18639 0.0161662817551963 0.856032175099727 0.713197087615114 0.821874739061227 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/352 132/18639 0.0151515151515152 0.802298553719008 0.715244837647703 0.822928291810194 GO:0008235 metalloexopeptidase activity 1/352 66/18639 0.0151515151515152 0.802298553719008 0.716504467124595 0.82307316951338 GO:0008173 RNA methyltransferase activity 1/352 67/18639 0.0149253731343284 0.79032394843962 0.721877343212042 0.826629260523568 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/352 67/18639 0.0149253731343284 0.79032394843962 0.721877343212042 0.826629260523568 GO:0003777 microtubule motor activity 1/352 68/18639 0.0147058823529412 0.778701537433155 0.727148675065873 0.828744015852157 GO:0030145 manganese ion binding 1/352 68/18639 0.0147058823529412 0.778701537433155 0.727148675065873 0.828744015852157 GO:1990841 promoter-specific chromatin binding 1/352 68/18639 0.0147058823529412 0.778701537433155 0.727148675065873 0.828744015852157 GO:0016779 nucleotidyltransferase activity 2/352 136/18639 0.0147058823529412 0.778701537433155 0.730511424533544 0.829429942748226 GO:0140789 histone phosphatase activity 2/352 136/18639 0.0147058823529412 0.778701537433155 0.730511424533544 0.829429942748226 GO:0002039 p53 binding 1/352 69/18639 0.0144927536231884 0.767416007905138 0.732320376448503 0.829429942748226 GO:0098960 postsynaptic neurotransmitter receptor activity 1/352 69/18639 0.0144927536231884 0.767416007905138 0.732320376448503 0.829429942748226 GO:0140098 catalytic activity, acting on RNA 6/352 387/18639 0.0155038759689922 0.82095665961945 0.742324625316713 0.83819958948509 GO:0140299 molecular sensor activity 1/352 71/18639 0.0140845070422535 0.745798655569782 0.742372363689962 0.83819958948509 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/352 73/18639 0.0136986301369863 0.725365815691158 0.752047907745108 0.84780556059464 GO:0005096 GTPase activator activity 4/352 271/18639 0.014760147601476 0.781574974840657 0.7558960575006 0.849149492287258 GO:0031491 nucleosome binding 1/352 74/18639 0.0135135135135135 0.715563574938575 0.756748927699526 0.849149492287258 GO:0035064 methylated histone binding 1/352 74/18639 0.0135135135135135 0.715563574938575 0.756748927699526 0.849149492287258 GO:0008094 ATP-dependent activity, acting on DNA 3/352 210/18639 0.0142857142857143 0.756452922077922 0.761293590238727 0.851471173680374 GO:0044183 protein folding chaperone 1/352 75/18639 0.0133333333333333 0.706022727272727 0.761361067610636 0.851471173680374 GO:0008194 UDP-glycosyltransferase activity 2/352 145/18639 0.0137931034482759 0.730368338557994 0.762336450264798 0.851471173680374 GO:0015293 symporter activity 2/352 146/18639 0.0136986301369863 0.725365815691158 0.765664195864377 0.85281171521484 GO:0140034 methylation-dependent protein binding 1/352 76/18639 0.0131578947368421 0.696732954545455 0.765886003195696 0.85281171521484 GO:0019209 kinase activator activity 2/352 148/18639 0.0135135135135135 0.715563574938575 0.772198626708542 0.858524047458502 GO:0008509 monoatomic anion transmembrane transporter activity 2/352 149/18639 0.0134228187919463 0.710761134838316 0.775405986381965 0.860768226009525 GO:0015370 solute:sodium symporter activity 1/352 79/18639 0.0126582278481013 0.670274741081703 0.77895387212663 0.860768226009525 GO:0046332 SMAD binding 1/352 79/18639 0.0126582278481013 0.670274741081703 0.77895387212663 0.860768226009525 GO:0033192 calmodulin-dependent protein phosphatase activity 1/352 81/18639 0.0123456790123457 0.653724747474747 0.787259093760777 0.860768226009525 GO:0140791 histone H2AXS140 phosphatase activity 1/352 81/18639 0.0123456790123457 0.653724747474747 0.787259093760777 0.860768226009525 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/352 81/18639 0.0123456790123457 0.653724747474747 0.787259093760777 0.860768226009525 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/352 81/18639 0.0123456790123457 0.653724747474747 0.787259093760777 0.860768226009525 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/352 81/18639 0.0123456790123457 0.653724747474747 0.787259093760777 0.860768226009525 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/352 81/18639 0.0123456790123457 0.653724747474747 0.787259093760777 0.860768226009525 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/352 81/18639 0.0123456790123457 0.653724747474747 0.787259093760777 0.860768226009525 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/352 81/18639 0.0123456790123457 0.653724747474747 0.787259093760777 0.860768226009525 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/352 82/18639 0.0121951219512195 0.645752494456763 0.79129426991102 0.862582041975076 GO:0033549 MAP kinase phosphatase activity 1/352 82/18639 0.0121951219512195 0.645752494456763 0.79129426991102 0.862582041975076 GO:0004386 helicase activity 2/352 155/18639 0.0129032258064516 0.68324780058651 0.793833640095117 0.864052807659752 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/352 83/18639 0.0120481927710843 0.637972343921139 0.795253121934047 0.864302045694788 GO:0017018 myosin phosphatase activity 1/352 84/18639 0.0119047619047619 0.630377435064935 0.799137089442089 0.867225002892312 GO:0016887 ATP hydrolysis activity 6/352 417/18639 0.0143884892086331 0.761895029431001 0.802781803193707 0.869879983759151 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/352 86/18639 0.0116279069767442 0.615717494714588 0.806685994482053 0.872807797308451 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 3/352 229/18639 0.0131004366812227 0.69369045256054 0.810224677073713 0.875237880461326 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 7/352 484/18639 0.0144628099173554 0.765830437640872 0.811874887282365 0.875237880461326 GO:0005085 guanyl-nucleotide exchange factor activity 3/352 230/18639 0.0130434782608696 0.690674407114624 0.812548665882829 0.875237880461326 GO:0106310 protein serine kinase activity 5/352 361/18639 0.0138504155124654 0.733403110047847 0.815039209243459 0.876619949497409 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/352 89/18639 0.0112359550561798 0.594962972420838 0.817482178430392 0.876650017046477 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/352 89/18639 0.0112359550561798 0.594962972420838 0.817482178430392 0.876650017046477 GO:0015081 sodium ion transmembrane transporter activity 2/352 164/18639 0.0121951219512195 0.645752494456763 0.818974738145227 0.876955250580288 GO:0140793 histone H2AXY142 phosphatase activity 1/352 90/18639 0.0111111111111111 0.588352272727273 0.820945589384166 0.87777098364198 GO:0001216 DNA-binding transcription activator activity 7/352 491/18639 0.0142566191446029 0.754912284762081 0.823116882562299 0.878798318735631 GO:0052689 carboxylic ester hydrolase activity 1/352 92/18639 0.0108695652173913 0.575562005928854 0.827677035134943 0.882369350231966 GO:0051219 phosphoprotein binding 1/352 93/18639 0.010752688172043 0.569373167155425 0.830947520045306 0.884557037467584 GO:0008276 protein methyltransferase activity 1/352 95/18639 0.0105263157894737 0.557386363636364 0.837303967299341 0.890018565533414 GO:0016407 acetyltransferase activity 1/352 96/18639 0.0104166666666667 0.551580255681818 0.840392244020148 0.891696678241794 GO:0140030 modification-dependent protein binding 2/352 173/18639 0.0115606936416185 0.612158434051498 0.841339152335577 0.891696678241794 GO:0003823 antigen binding 2/352 174/18639 0.0114942528735632 0.608640282131661 0.843663522346954 0.892856730647068 GO:0004721 phosphoprotein phosphatase activity 2/352 175/18639 0.0114285714285714 0.605162337662338 0.84595701543247 0.893143062101301 GO:0004725 protein tyrosine phosphatase activity 1/352 98/18639 0.0102040816326531 0.540323515769944 0.846394527170379 0.893143062101301 GO:0004722 protein serine/threonine phosphatase activity 1/352 103/18639 0.00970873786407767 0.514094218887908 0.860433720626588 0.905325914746236 GO:0005253 monoatomic anion channel activity 1/352 103/18639 0.00970873786407767 0.514094218887908 0.860433720626588 0.905325914746236 GO:0000149 SNARE binding 1/352 106/18639 0.00943396226415094 0.499544382504288 0.868235218539949 0.910894174364166 GO:0004497 monooxygenase activity 1/352 106/18639 0.00943396226415094 0.499544382504288 0.868235218539949 0.910894174364166 GO:0008234 cysteine-type peptidase activity 2/352 187/18639 0.0106951871657754 0.566328390860476 0.871190120934294 0.912675364788308 GO:0004620 phospholipase activity 1/352 109/18639 0.00917431192660551 0.485795454545455 0.875601796629135 0.915975366502525 GO:1902936 phosphatidylinositol bisphosphate binding 1/352 111/18639 0.00900900900900901 0.477042383292383 0.880283223706135 0.919547655267128 GO:0016757 glycosyltransferase activity 3/352 267/18639 0.0112359550561798 0.594962972420838 0.883016187844408 0.921077230423908 GO:0017124 SH3 domain binding 1/352 115/18639 0.00869565217391304 0.460449604743083 0.889125575738807 0.923606636474162 GO:0101005 deubiquitinase activity 1/352 115/18639 0.00869565217391304 0.460449604743083 0.889125575738807 0.923606636474162 GO:0016758 hexosyltransferase activity 2/352 197/18639 0.0101522842639594 0.537580756806645 0.889257629332561 0.923606636474162 GO:0009055 electron transfer activity 1/352 116/18639 0.00862068965517241 0.456480211598746 0.891232453159447 0.924335372848226 GO:0008168 methyltransferase activity 2/352 204/18639 0.00980392156862745 0.51913435828877 0.900477371102097 0.931992525976719 GO:0015108 chloride transmembrane transporter activity 1/352 121/18639 0.00826446280991736 0.437617392937641 0.901182855696497 0.931992525976719 GO:0030695 GTPase regulator activity 6/352 489/18639 0.0122699386503067 0.649714166201896 0.903058193584449 0.932320852238864 GO:0060589 nucleoside-triphosphatase regulator activity 6/352 490/18639 0.0122448979591837 0.648388218923933 0.904068705201323 0.932320852238864 GO:0015291 secondary active transmembrane transporter activity 3/352 287/18639 0.0104529616724739 0.553502138105797 0.910356036530922 0.937473024853119 GO:0019783 ubiquitin-like protein peptidase activity 1/352 127/18639 0.0078740157480315 0.41694255547602 0.911932257934923 0.937766032947244 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 1/352 128/18639 0.0078125 0.413685191761364 0.913606839028641 0.938159215183583 GO:0016741 transferase activity, transferring one-carbon groups 2/352 215/18639 0.00930232558139535 0.49257399577167 0.915991016054828 0.938845324340881 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/352 130/18639 0.00769230769230769 0.407320804195804 0.916861342916921 0.938845324340881 GO:0015297 antiporter activity 1/352 135/18639 0.00740740740740741 0.392234848484848 0.924472667508311 0.945305854381737 GO:0099094 ligand-gated monoatomic cation channel activity 1/352 136/18639 0.00735294117647059 0.389350768716578 0.925909417456272 0.945443371411045 GO:0016922 nuclear receptor binding 1/352 137/18639 0.0072992700729927 0.386508792302588 0.927318912406031 0.945552711245475 GO:0030295 protein kinase activator activity 1/352 139/18639 0.00719424460431655 0.3809475147155 0.930058189902585 0.947015772607681 GO:0003774 cytoskeletal motor activity 1/352 153/18639 0.0065359477124183 0.346089572192513 0.946556609433605 0.962465123877867 GO:0003924 GTPase activity 3/352 331/18639 0.00906344410876133 0.479924814611371 0.951246280899415 0.965880839067098 GO:0005178 integrin binding 1/352 161/18639 0.0062111801242236 0.328892574816488 0.954176682039993 0.967503172012619 GO:0015103 inorganic anion transmembrane transporter activity 1/352 165/18639 0.00606060606060606 0.320919421487603 0.957570115957279 0.969589824525781 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 1/352 167/18639 0.00598802395209581 0.317076075122482 0.959171656327051 0.969858805701169 GO:1901981 phosphatidylinositol phosphate binding 1/352 185/18639 0.00540540540540541 0.28622542997543 0.971127209474143 0.978137366078877 GO:0015276 ligand-gated monoatomic ion channel activity 1/352 186/18639 0.00537634408602151 0.284686583577713 0.971677942229378 0.978137366078877 GO:0035091 phosphatidylinositol binding 2/352 284/18639 0.00704225352112676 0.372899327784891 0.972033434590078 0.978137366078877 GO:0022834 ligand-gated channel activity 1/352 188/18639 0.00531914893617021 0.281658002901354 0.97274817948891 0.978137366078877 GO:0005525 GTP binding 3/352 378/18639 0.00793650793650794 0.420251623376623 0.975313000569266 0.979359942480341 GO:0019001 guanyl nucleotide binding 3/352 400/18639 0.0075 0.397137784090909 0.982208093786905 0.983562863571439 GO:0032561 guanyl ribonucleotide binding 3/352 400/18639 0.0075 0.397137784090909 0.982208093786905 0.983562863571439 GO:0030371 translation repressor activity 2/352 329/18639 0.0060790273556231 0.32189486045869 0.986713534764835 0.986713534764835