category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Organismal Systems Immune system hsa04612 Antigen processing and presentation 6/48 82/9376 14.2926829268293 B2M/HLA-A/HSPA8/HSP90AA1/HSPA1A/HLA-C 8.67221878560763 Cellular Processes Transport and catabolism hsa04145 Phagosome 5/48 155/9376 6.3010752688172 HLA-A/CD36/FCGR2B/TUBB4B/HLA-C 4.77367443738672 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 5/48 196/9376 4.98299319727891 GNGT1/HLA-A/UBB/UBC/HLA-C 4.04229726633532 Environmental Information Processing Signal transduction hsa04010 MAPK signaling pathway 6/48 300/9376 3.90666666666667 HSPB1/FGFR3/HSPA8/GADD45B/HSPA1A/STMN1 3.67046090072244 Organismal Systems Endocrine system hsa04915 Estrogen signaling pathway 4/48 139/9376 5.621103117506 POMC/HSPA8/HSP90AA1/HSPA1A 3.93730969463596 Cellular Processes Transport and catabolism hsa04144 Endocytosis 5/48 250/9376 3.90666666666667 HLA-A/FGFR3/HSPA8/HSPA1A/HLA-C 3.3414655695263 Environmental Information Processing Signaling molecules and interaction hsa04514 Cell adhesion molecule (CAM) interaction 4/48 160/9376 4.88333333333333 HLA-A/ITGA9/CLDN5/HLA-C 3.55390174867655 Genetic Information Processing Folding, sorting and degradation hsa04141 Protein processing in endoplasmic reticulum 4/48 174/9376 4.4904214559387 HSPA8/HSP90AA1/DNAJA1/HSPA1A 3.33367583905866 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 4/48 180/9376 4.34074074074074 B2M/HLA-A/HLA-C/SRSF7 3.24632153564373 Human Diseases Immune disease hsa05330 Allograft rejection 2/48 39/9376 10.017094017094 HLA-A/HLA-C 4.04768968625695 Cellular Processes Cell motility hsa04814 Motor proteins 4/48 194/9376 4.02749140893471 TNNT3/MYL12B/TUBB4B/DYNLL1 3.05651920094208 Environmental Information Processing Signal transduction hsa04350 TGF-beta signaling pathway 3/48 110/9376 5.32727272727273 ID1/IGSF1/ID3 3.27473717816526 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 4/48 205/9376 3.81138211382114 B2M/HLA-A/GADD45B/HLA-C 2.91944601895329 Human Diseases Endocrine and metabolic disease hsa04940 Type I diabetes mellitus 2/48 44/9376 8.87878787878788 HLA-A/HLA-C 3.75759846233397 Human Diseases Immune disease hsa05332 Graft-versus-host disease 2/48 45/9376 8.68148148148148 HLA-A/HLA-C 3.70509321115239 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 4/48 214/9376 3.65109034267913 GNGT1/B2M/HLA-A/HLA-C 2.81415658549429 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 4/48 216/9376 3.61728395061728 CD36/HSPA8/HSP90AA1/HSPA1A 2.79152787554846 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 5/48 333/9376 2.93293293293293 HLA-A/HES5/ITGA9/HLA-C/HES4 2.5762892720245 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 4/48 227/9376 3.44199706314244 GNGT1/B2M/HLA-A/HLA-C 2.67167262349894 Human Diseases Immune disease hsa05320 Autoimmune thyroid disease 2/48 54/9376 7.23456790123457 HLA-A/HLA-C 3.29579869948528 Human Diseases Infectious disease: viral hsa05162 Measles 3/48 136/9376 4.30882352941177 FCGR2B/HSPA8/HSPA1A 2.78816879413763 Human Diseases Infectious disease: bacterial hsa05134 Legionellosis 2/48 56/9376 6.97619047619048 HSPA8/HSPA1A 3.21752904922094 Cellular Processes Cellular community - eukaryotes hsa04550 Signaling pathways regulating pluripotency of stem cells 3/48 144/9376 4.06944444444444 ID1/ID3/FGFR3 2.66259500890291 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 4/48 248/9376 3.1505376344086 MYL12B/TUBB4B/HSP90AA1/DYNLL1 2.46205108585358 Organismal Systems Aging hsa04213 Longevity regulating pathway - multiple species 2/48 62/9376 6.3010752688172 HSPA8/HSPA1A 3.0040259976809 Cellular Processes Cell growth and death hsa04218 Cellular senescence 3/48 157/9376 3.73248407643312 HLA-A/GADD45B/HLA-C 2.47672362414408 Organismal Systems Endocrine system hsa04920 Adipocytokine signaling pathway 2/48 70/9376 5.58095238095238 POMC/CD36 2.7595308995399 Human Diseases Cardiovascular disease hsa05416 Viral myocarditis 2/48 70/9376 5.58095238095238 HLA-A/HLA-C 2.7595308995399 Organismal Systems Endocrine system hsa03320 PPAR signaling pathway 2/48 76/9376 5.14035087719298 CD36/UBC 2.59964746211973 Genetic Information Processing Information processing in viruses hsa03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus 1/48 12/9376 16.2777777777778 FCGR2B 3.79867463996077 Environmental Information Processing Signaling molecules and interaction hsa04512 ECM-receptor interaction 2/48 89/9376 4.38951310861423 CD36/ITGA9 2.30465852665492 Cellular Processes Cellular community - eukaryotes hsa04540 Gap junction 2/48 89/9376 4.38951310861423 TUBB4B/GUCY1A1 2.30465852665492 Human Diseases Cancer: overview hsa05202 Transcriptional misregulation in cancer 3/48 201/9376 2.91542288557214 RUNX1T1/LMO2/GADD45B 1.96911759360507 Organismal Systems Environmental adaptation hsa04713 Circadian entrainment 2/48 97/9376 4.02749140893471 GNGT1/GUCY1A1 2.14995904671346 Cellular Processes Transport and catabolism hsa04137 Mitophagy - animal 2/48 105/9376 3.72063492063492 UBB/UBC 2.01100715280794 NA NA hsa04081 Hormone signaling 3/48 219/9376 2.67579908675799 GNGT1/POMC/RAMP2 1.80002852710926 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 3/48 224/9376 2.61607142857143 B2M/HLA-A/HLA-C 1.75605673807322 Human Diseases Infectious disease: parasitic hsa05145 Toxoplasmosis 2/48 112/9376 3.48809523809524 HSPA8/HSPA1A 1.90015367682447 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 4/48 362/9376 2.15837937384899 GNGT1/FGFR3/ITGA9/HSP90AA1 1.61234625214058 Cellular Processes Cell motility hsa04810 Regulation of actin cytoskeleton 3/48 232/9376 2.52586206896552 FGFR3/MYL12B/ITGA9 1.6881193542048 Cellular Processes Cell motility hsa04820 Cytoskeleton in muscle cells 3/48 233/9376 2.51502145922747 TNNT3/ITGA9/FBLN2 1.67982628728999 Organismal Systems Immune system hsa04670 Leukocyte transendothelial migration 2/48 116/9376 3.36781609195402 MYL12B/CLDN5 1.84070188559498 Genetic Information Processing Transcription hsa03040 Spliceosome 3/48 243/9376 2.41152263374486 HSPA8/HSPA1A/SRSF7 1.59917592346384 Metabolism Metabolism of cofactors and vitamins hsa00790 Folate biosynthesis 1/48 28/9376 6.97619047619048 DHFR 2.27172670353093 Organismal Systems Immune system hsa04611 Platelet activation 2/48 126/9376 3.1005291005291 MYL12B/GUCY1A1 1.70276649851656 Organismal Systems Sensory system hsa04744 Phototransduction 1/48 29/9376 6.73563218390805 GNGT1 2.21899415766148 Human Diseases Infectious disease: bacterial hsa05131 Shigellosis 3/48 253/9376 2.31620553359684 UBB/MYL12B/UBC 1.52239421035769 Human Diseases Drug resistance: antineoplastic hsa01523 Antifolate resistance 1/48 30/9376 6.51111111111111 DHFR 2.16869707763848 Genetic Information Processing Folding, sorting and degradation hsa03060 Protein export 1/48 31/9376 6.3010752688172 SRP14 2.12064099637777 NA NA hsa04981 Folate transport and metabolism 1/48 31/9376 6.3010752688172 DHFR 2.12064099637777 Organismal Systems Immune system hsa04650 Natural killer cell mediated cytotoxicity 2/48 133/9376 2.93734335839599 HLA-A/HLA-C 1.61412784823823 Organismal Systems Circulatory system hsa04270 Vascular smooth muscle contraction 2/48 134/9376 2.91542288557214 RAMP2/GUCY1A1 1.60193937893746 Human Diseases Immune disease hsa05310 Asthma 1/48 32/9376 6.10416666666667 PRG2 2.07465271846572 Cellular Processes Cell growth and death hsa04210 Apoptosis 2/48 137/9376 2.85158150851582 GADD45B/CTSC 1.56603917938851 Human Diseases Neurodegenerative disease hsa05012 Parkinson disease 3/48 268/9376 2.1865671641791 UBB/UBC/TUBB4B 1.41370957731302 Genetic Information Processing Folding, sorting and degradation hsa04120 Ubiquitin mediated proteolysis 2/48 142/9376 2.75117370892019 UBB/UBC 1.50830945554363 Organismal Systems Development and regeneration hsa04380 Osteoclast differentiation 2/48 142/9376 2.75117370892019 JUNB/FCGR2B 1.50830945554363 Human Diseases Neurodegenerative disease hsa05020 Prion disease 3/48 275/9376 2.13090909090909 TUBB4B/HSPA8/HSPA1A 1.36540495044874 Human Diseases Cancer: specific types hsa05216 Thyroid cancer 1/48 37/9376 5.27927927927928 GADD45B 1.87082555380229 Human Diseases Cancer: specific types hsa05224 Breast cancer 2/48 148/9376 2.63963963963964 HES5/GADD45B 1.44223975346015 Metabolism Metabolism of cofactors and vitamins hsa00760 Nicotinate and nicotinamide metabolism 1/48 38/9376 5.14035087719298 NAPRT 1.83448429868025 Metabolism Metabolism of cofactors and vitamins hsa00670 One carbon pool by folate 1/48 39/9376 5.00854700854701 DHFR 1.79939949085735 Metabolism Global and overview maps hsa01240 Biosynthesis of cofactors 2/48 154/9376 2.53679653679654 DHFR/NAPRT 1.37935534725518 Human Diseases Cancer: specific types hsa05219 Bladder cancer 1/48 41/9376 4.76422764227642 FGFR3 1.73269704595956 Cellular Processes Cell growth and death hsa04216 Ferroptosis 1/48 42/9376 4.65079365079365 FTL 1.70094402370349 NA NA hsa04517 IgSF CAM signaling 3/48 299/9376 1.95986622073579 MYL12B/TUBB4B/DYNLL1 1.21000488329207 Organismal Systems Digestive system hsa04975 Fat digestion and absorption 1/48 43/9376 4.54263565891473 CD36 1.67017536212214 Organismal Systems Excretory system hsa04962 Vasopressin-regulated water reabsorption 1/48 44/9376 4.43939393939394 DYNLL1 1.64033625182656 Metabolism Metabolism of cofactors and vitamins hsa00860 Porphyrin metabolism 1/48 46/9376 4.2463768115942 FTL 1.58324822477456 Cellular Processes Cell growth and death hsa04217 Necroptosis 2/48 168/9376 2.32539682539683 FTL/HSP90AA1 1.24345450400601 Cellular Processes Transport and catabolism hsa04140 Autophagy - animal 2/48 169/9376 2.31163708086785 UBB/UBC 1.23426937948607 Cellular Processes Cellular community - eukaryotes hsa04530 Tight junction 2/48 170/9376 2.29803921568627 MYL12B/CLDN5 1.22514862495768 NA NA hsa03272 Virion - Hepatitis viruses 1/48 48/9376 4.06944444444444 CLDN5 1.52931911004831 Metabolism Amino acid metabolism hsa00330 Arginine and proline metabolism 1/48 50/9376 3.90666666666667 AMD1 1.47823852016503 Human Diseases Infectious disease: parasitic hsa05144 Malaria 1/48 50/9376 3.90666666666667 CD36 1.47823852016503 Organismal Systems Digestive system hsa04979 Cholesterol metabolism 1/48 52/9376 3.75641025641026 CD36 1.42973775197868 Metabolism Amino acid metabolism hsa00270 Cysteine and methionine metabolism 1/48 54/9376 3.61728395061728 AMD1 1.38358282037798 Organismal Systems Immune system hsa04621 NOD-like receptor signaling pathway 2/48 187/9376 2.08912655971479 TXNIP/HSP90AA1 1.07913807187675 Human Diseases Cancer: specific types hsa05213 Endometrial cancer 1/48 59/9376 3.31073446327684 GADD45B 1.27717376200434 Environmental Information Processing Signal transduction hsa04370 VEGF signaling pathway 1/48 60/9376 3.25555555555556 HSPB1 1.25726377303374 Organismal Systems Nervous system hsa04730 Long-term depression 1/48 60/9376 3.25555555555556 GUCY1A1 1.25726377303374 Organismal Systems Digestive system hsa04978 Mineral absorption 1/48 61/9376 3.20218579234973 FTL 1.23776851810735 NA NA hsa04082 Neuroactive ligand signaling 2/48 199/9376 1.96314907872697 GNGT1/POMC 0.985103073572065 Human Diseases Infectious disease: bacterial hsa05130 Pathogenic Escherichia coli infection 2/48 200/9376 1.95333333333333 TUBB4B/CLDN5 0.97756368984958 Environmental Information Processing Signal transduction hsa04330 Notch signaling pathway 1/48 62/9376 3.1505376344086 HES5 1.21867180433302 Metabolism Lipid metabolism hsa00590 Arachidonic acid metabolism 1/48 63/9376 3.1005291005291 PTGDS 1.19995832753957 Human Diseases Cancer: specific types hsa05217 Basal cell carcinoma 1/48 63/9376 3.1005291005291 GADD45B 1.19995832753957 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 2/48 203/9376 1.92446633825944 MYL12B/ITGA9 0.955202416771554 Human Diseases Cancer: overview hsa05203 Viral carcinogenesis 2/48 205/9376 1.90569105691057 HLA-A/HLA-C 0.940504009576046 Organismal Systems Endocrine system hsa04927 Cortisol synthesis and secretion 1/48 65/9376 3.00512820512821 POMC 1.16362394406754 Human Diseases Cancer: specific types hsa05221 Acute myeloid leukemia 1/48 68/9376 2.87254901960784 RUNX1T1 1.11165865271052 Environmental Information Processing Signal transduction hsa04015 Rap1 signaling pathway 2/48 212/9376 1.84276729559748 ID1/FGFR3 0.89031779216501 Organismal Systems Endocrine system hsa04924 Renin secretion 1/48 69/9376 2.83091787439614 GUCY1A1 1.09496576572423 Human Diseases Cancer: overview hsa05204 Chemical carcinogenesis - DNA adducts 1/48 70/9376 2.79047619047619 SULT1A1 1.07856924971622 Human Diseases Cancer: overview hsa05230 Central carbon metabolism in cancer 1/48 71/9376 2.75117370892019 FGFR3 1.06245905488492 Human Diseases Cancer: specific types hsa05218 Melanoma 1/48 73/9376 2.67579908675799 GADD45B 1.03105980640645 Human Diseases Cancer: specific types hsa05223 Non-small cell lung cancer 1/48 73/9376 2.67579908675799 GADD45B 1.03105980640645 Cellular Processes Cell growth and death hsa04115 p53 signaling pathway 1/48 75/9376 2.60444444444444 GADD45B 1.00069673195853 Human Diseases Cancer: specific types hsa05214 Glioma 1/48 76/9376 2.57017543859649 GADD45B 0.985883253642863 Human Diseases Cancer: specific types hsa05212 Pancreatic cancer 1/48 77/9376 2.53679653679654 GADD45B 0.971304945671455 Human Diseases Cancer: specific types hsa05220 Chronic myeloid leukemia 1/48 77/9376 2.53679653679654 GADD45B 0.971304945671455 Human Diseases Drug resistance: antineoplastic hsa01521 EGFR tyrosine kinase inhibitor resistance 1/48 80/9376 2.44166666666667 FGFR3 0.928910305899481 Environmental Information Processing Signal transduction hsa04014 Ras signaling pathway 2/48 238/9376 1.64145658263305 GNGT1/FGFR3 0.719021962469349 Human Diseases Cardiovascular disease hsa05412 Arrhythmogenic right ventricular cardiomyopathy 1/48 86/9376 2.27131782945736 ITGA9 0.849586288210574 Human Diseases Cancer: specific types hsa05210 Colorectal cancer 1/48 87/9376 2.24521072796935 GADD45B 0.837008728039908 Organismal Systems Immune system hsa04610 Complement and coagulation cascades 1/48 88/9376 2.21969696969697 CLU 0.824601585901752 Organismal Systems Nervous system hsa04727 GABAergic synapse 1/48 89/9376 2.19475655430712 GNGT1 0.812360298345766 Organismal Systems Immune system hsa04662 B cell receptor signaling pathway 1/48 91/9376 2.14652014652015 FCGR2B 0.788357894258701 Human Diseases Substance dependence hsa05032 Morphine addiction 1/48 91/9376 2.14652014652015 GNGT1 0.788357894258701 Cellular Processes Cellular community - eukaryotes hsa04520 Adherens junction 1/48 93/9376 2.10035842293907 MYL12B 0.764968336828084 Organismal Systems Digestive system hsa04970 Salivary secretion 1/48 93/9376 2.10035842293907 GUCY1A1 0.764968336828084 Human Diseases Cancer: specific types hsa05222 Small cell lung cancer 1/48 93/9376 2.10035842293907 GADD45B 0.764968336828084 Organismal Systems Immune system hsa04657 IL-17 signaling pathway 1/48 94/9376 2.07801418439716 HSP90AA1 0.753493670020963 Organismal Systems Immune system hsa04666 Fc gamma R-mediated phagocytosis 1/48 98/9376 1.99319727891156 FCGR2B 0.708978986003173 Organismal Systems Endocrine system hsa04925 Aldosterone synthesis and secretion 1/48 98/9376 1.99319727891156 POMC 0.708978986003173 Human Diseases Infectious disease: bacterial hsa05150 Staphylococcus aureus infection 1/48 99/9376 1.97306397306397 FCGR2B 0.698179673208098 Human Diseases Cardiovascular disease hsa05410 Hypertrophic cardiomyopathy 1/48 99/9376 1.97306397306397 ITGA9 0.698179673208098 Organismal Systems Immune system hsa04640 Hematopoietic cell lineage 1/48 100/9376 1.95333333333333 CD36 0.68750584789266 Organismal Systems Endocrine system hsa04916 Melanogenesis 1/48 101/9376 1.93399339933993 POMC 0.676954567692083 Genetic Information Processing Translation hsa03015 mRNA surveillance pathway 1/48 103/9376 1.89644012944984 SAP18 0.656208362034518 Human Diseases Infectious disease: parasitic hsa05146 Amoebiasis 1/48 103/9376 1.89644012944984 HSPB1 0.656208362034518 Environmental Information Processing Signal transduction hsa04064 NF-kappa B signaling pathway 1/48 105/9376 1.86031746031746 GADD45B 0.635919414715229 Human Diseases Cardiovascular disease hsa05414 Dilated cardiomyopathy 1/48 105/9376 1.86031746031746 ITGA9 0.635919414715229 Human Diseases Cancer: specific types hsa05215 Prostate cancer 1/48 106/9376 1.84276729559748 HSP90AA1 0.625940032051801 Genetic Information Processing Translation hsa03013 Nucleocytoplasmic transport 1/48 108/9376 1.80864197530864 SAP18 0.606299394450484 Organismal Systems Immune system hsa04659 Th17 cell differentiation 1/48 109/9376 1.79204892966361 HSP90AA1 0.596633544541223 Human Diseases Endocrine and metabolic disease hsa04931 Insulin resistance 1/48 109/9376 1.79204892966361 CD36 0.596633544541223 Organismal Systems Endocrine system hsa04914 Progesterone-mediated oocyte maturation 1/48 110/9376 1.77575757575758 HSP90AA1 0.587067729418981 Organismal Systems Nervous system hsa04725 Cholinergic synapse 1/48 115/9376 1.69855072463768 GNGT1 0.540667063304631 Organismal Systems Nervous system hsa04726 Serotonergic synapse 1/48 115/9376 1.69855072463768 GNGT1 0.540667063304631 Human Diseases Neurodegenerative disease hsa05022 Pathways of neurodegeneration - multiple diseases 3/48 480/9376 1.22083333333333 UBB/UBC/TUBB4B 0.356286894409812 Organismal Systems Nervous system hsa04724 Glutamatergic synapse 1/48 116/9376 1.68390804597701 GNGT1 0.531659039771366 Environmental Information Processing Signal transduction hsa04668 TNF signaling pathway 1/48 119/9376 1.64145658263305 JUNB 0.505146796592981 Environmental Information Processing Signal transduction hsa04152 AMPK signaling pathway 1/48 122/9376 1.60109289617486 CD36 0.479367681928078 Organismal Systems Endocrine system hsa04935 Growth hormone synthesis, secretion and action 1/48 122/9376 1.60109289617486 JUNB 0.479367681928078 Metabolism Nucleotide metabolism hsa00230 Purine metabolism 1/48 128/9376 1.52604166666667 GUCY1A1 0.429846314592373 Organismal Systems Endocrine system hsa04926 Relaxin signaling pathway 1/48 130/9376 1.5025641025641 GNGT1 0.413902628217921 Human Diseases Cancer: overview hsa05206 MicroRNAs in cancer 2/48 323/9376 1.20949432404541 FGFR3/STMN1 0.274845891924218 Environmental Information Processing Signal transduction hsa04068 FoxO signaling pathway 1/48 133/9376 1.468671679198 GADD45B 0.390481122406919 Organismal Systems Nervous system hsa04728 Dopaminergic synapse 1/48 133/9376 1.468671679198 GNGT1 0.390481122406919 Environmental Information Processing Signal transduction hsa04371 Apelin signaling pathway 1/48 140/9376 1.3952380952381 GNGT1 0.337981431879693 Human Diseases Cardiovascular disease hsa05418 Fluid shear stress and atherosclerosis 1/48 142/9376 1.37558685446009 HSP90AA1 0.323498006550913 Organismal Systems Nervous system hsa04723 Retrograde endocannabinoid signaling 1/48 149/9376 1.31096196868009 GNGT1 0.274461946592315 Human Diseases Cancer: specific types hsa05226 Gastric cancer 1/48 150/9376 1.30222222222222 GADD45B 0.267656187251396 NA NA hsa04518 Integrin signaling 1/48 154/9376 1.26839826839827 ITGA9 0.240901497267102 Organismal Systems Endocrine system hsa04921 Oxytocin signaling pathway 1/48 154/9376 1.26839826839827 GUCY1A1 0.240901497267102 Human Diseases Endocrine and metabolic disease hsa04934 Cushing syndrome 1/48 155/9376 1.26021505376344 POMC 0.234326412545149 Human Diseases Infectious disease: viral hsa05160 Hepatitis C 1/48 156/9376 1.25213675213675 CLDN5 0.227795416355803 Cellular Processes Transport and catabolism hsa04148 Efferocytosis 1/48 157/9376 1.24416135881104 CD36 0.221307860743255 Environmental Information Processing Signal transduction hsa04390 Hippo signaling pathway 1/48 157/9376 1.24416135881104 ID1 0.221307860743255 Cellular Processes Cell growth and death hsa04110 Cell cycle 1/48 158/9376 1.23628691983122 GADD45B 0.214863111581032 Human Diseases Neurodegenerative disease hsa05014 Amyotrophic lateral sclerosis 2/48 368/9376 1.06159420289855 TUBB4B/SRSF7 0.0864692213257391 Environmental Information Processing Signal transduction hsa04022 cGMP-PKG signaling pathway 1/48 166/9376 1.17670682730924 GUCY1A1 0.16477432699908 Human Diseases Cancer: specific types hsa05225 Hepatocellular carcinoma 1/48 170/9376 1.14901960784314 GADD45B 0.140651503771576 Human Diseases Infectious disease: bacterial hsa05152 Tuberculosis 1/48 181/9376 1.07918968692449 FCGR2B 0.0771692065393664 Organismal Systems Development and regeneration hsa04360 Axon guidance 1/48 184/9376 1.06159420289855 MYL12B 0.0605279173822926 Human Diseases Substance dependence hsa05034 Alcoholism 1/48 191/9376 1.02268760907504 GNGT1 0.0227236358919673 Organismal Systems Immune system hsa04062 Chemokine signaling pathway 1/48 193/9376 1.01208981001727 GNGT1 0.0121735663408275 Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 1/48 205/9376 0.952845528455284 CD36 -0.0489669951125769 NA NA hsa04382 Cornified envelope formation 1/48 217/9376 0.900153609831029 CLDN5 -0.106745651862938 Human Diseases Cancer: overview hsa05207 Chemical carcinogenesis - receptor activation 1/48 217/9376 0.900153609831029 HSP90AA1 -0.106745651862938 Genetic Information Processing Translation hsa03010 Ribosome 1/48 222/9376 0.87987987987988 RPL10 -0.129926811053904 Environmental Information Processing Signal transduction hsa04024 cAMP signaling pathway 1/48 226/9376 0.864306784660767 POMC -0.148120030975575 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 1/48 238/9376 0.820728291316526 RPL10 -0.200949369423748 Cellular Processes Transport and catabolism hsa04142 Lysosome biogenesis 1/48 250/9376 0.781333333333333 CTSC -0.251376308900144 Environmental Information Processing Signal transduction hsa04020 Calcium signaling pathway 1/48 254/9376 0.769028871391076 FGFR3 -0.267695770175024 Human Diseases Neurodegenerative disease hsa05016 Huntington disease 1/48 308/9376 0.634199134199134 TUBB4B -0.468248419073824 Environmental Information Processing Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction 1/48 370/9376 0.527927927927928 POMC -0.664592119248367 Human Diseases Neurodegenerative disease hsa05010 Alzheimer disease 1/48 388/9376 0.503436426116838 TUBB4B -0.716590715954943