category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Human Diseases Immune disease hsa05310 Asthma 2/3 32/9376 195.333333333333 PRG2/HLA-DRB5 19.6998460093349 Metabolism Metabolism of cofactors and vitamins hsa00790 Folate biosynthesis 1/3 28/9376 111.619047619048 DHFR 10.4871272063308 Human Diseases Drug resistance: antineoplastic hsa01523 Antifolate resistance 1/3 30/9376 104.177777777778 DHFR 10.1260686168731 NA NA hsa04981 Folate transport and metabolism 1/3 31/9376 100.817204301075 DHFR 9.95872071347153 Metabolism Metabolism of cofactors and vitamins hsa00670 One carbon pool by folate 1/3 39/9376 80.1367521367521 DHFR 8.85959365637173 Human Diseases Immune disease hsa05330 Allograft rejection 1/3 39/9376 80.1367521367521 HLA-DRB5 8.85959365637173 Human Diseases Endocrine and metabolic disease hsa04940 Type I diabetes mellitus 1/3 44/9376 71.030303030303 HLA-DRB5 8.32974939903279 Human Diseases Immune disease hsa05332 Graft-versus-host disease 1/3 45/9376 69.4518518518519 HLA-DRB5 8.2344447694648 Organismal Systems Immune system hsa04672 Intestinal immune network for IgA production 1/3 50/9376 62.5066666666667 HLA-DRB5 7.80129040406911 Human Diseases Immune disease hsa05320 Autoimmune thyroid disease 1/3 54/9376 57.8765432098765 HLA-DRB5 7.49863960027252 Human Diseases Immune disease hsa05321 Inflammatory bowel disease 1/3 66/9376 47.3535353535354 HLA-DRB5 6.76062656248609 Human Diseases Cardiovascular disease hsa05416 Viral myocarditis 1/3 70/9376 44.6476190476191 HLA-DRB5 6.55745035201253 Human Diseases Infectious disease: parasitic hsa05140 Leishmaniasis 1/3 78/9376 40.0683760683761 HLA-DRB5 6.19847490131751 Organismal Systems Immune system hsa04612 Antigen processing and presentation 1/3 82/9376 38.1138211382114 HLA-DRB5 6.03876625609506 Organismal Systems Immune system hsa04658 Th1 and Th2 cell differentiation 1/3 93/9376 33.6057347670251 HLA-DRB5 5.65325073060634 Human Diseases Immune disease hsa05323 Rheumatoid arthritis 1/3 95/9376 32.8982456140351 HLA-DRB5 5.59033934324967 Human Diseases Infectious disease: bacterial hsa05150 Staphylococcus aureus infection 1/3 99/9376 31.5690235690236 HLA-DRB5 5.47018913812489 Organismal Systems Immune system hsa04640 Hematopoietic cell lineage 1/3 100/9376 31.2533333333333 HLA-DRB5 5.44126427538629 Organismal Systems Immune system hsa04659 Th17 cell differentiation 1/3 109/9376 28.6727828746177 HLA-DRB5 5.19880418727079 Human Diseases Infectious disease: parasitic hsa05145 Toxoplasmosis 1/3 112/9376 27.9047619047619 HLA-DRB5 5.12443334224333 Human Diseases Immune disease hsa05322 Systemic lupus erythematosus 1/3 143/9376 21.8554778554779 HLA-DRB5 4.49597308995568 Metabolism Global and overview maps hsa01240 Biosynthesis of cofactors 1/3 154/9376 20.2943722943723 DHFR 4.31902196497736 Cellular Processes Transport and catabolism hsa04145 Phagosome 1/3 155/9376 20.1634408602151 HLA-DRB5 4.30385157798316 Environmental Information Processing Signaling molecules and interaction hsa04514 Cell adhesion molecule (CAM) interaction 1/3 160/9376 19.5333333333333 HLA-DRB5 4.23008653847661 Human Diseases Infectious disease: viral hsa05164 Influenza A 1/3 173/9376 18.0655105973025 HLA-DRB5 4.05307447945171 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 1/3 180/9376 17.362962962963 HLA-DRB5 3.96557050453663 Human Diseases Infectious disease: bacterial hsa05152 Tuberculosis 1/3 181/9376 17.2670349907919 HLA-DRB5 3.95347301261621 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 1/3 205/9376 15.2455284552846 HLA-DRB5 3.68938608480611 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 1/3 224/9376 13.952380952381 HLA-DRB5 3.51012489712226