category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	9/38	238/9376	9.33038478549314	JUN/RPS26/FOS/RPL23A/RPL36/NFKBIA/RPS23/RPS13/RPS2	8.30383030713408
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	5/38	94/9376	13.1243001119821	JUN/FOS/FOSB/NFKBIA/HSP90AA1	7.53616371317784
Genetic Information Processing	Translation	hsa03010	Ribosome	6/38	222/9376	6.66856330014225	RPS26/RPL23A/RPL36/RPS23/RPS13/RPS2	5.45248570447107
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	5/38	142/9376	8.68791697553744	JUN/JUNB/FOS/FOSB/NFKBIA	5.88855076419257
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	5/38	142/9376	8.68791697553744	JUN/DUSP1/FOS/KLF2/HSP90AA1	5.88855076419257
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	6/38	224/9376	6.60902255639098	EGR1/JUN/FOS/HLA-B/NFKBIA/B2M	5.42005497623442
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	6/38	227/9376	6.52167864595409	JUN/MT-CO3/FOS/MT-ND1/NFKBIA/MT-CO1	5.37214522240148
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	4/38	103/9376	9.58201328564129	JUN/SERPINE1/FOS/NFKBIA	5.5866075851648
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	4/38	109/9376	9.05456301303718	JUN/FOS/NFKBIA/HSP90AA1	5.39555535690055
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	4/38	119/9376	8.29367536488279	JUN/JUNB/FOS/NFKBIA	5.10781641983654
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	5/38	214/9376	5.76487948844073	JUN/FOS/HLA-B/NFKBIA/B2M	4.49794525996795
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	3/38	69/9376	10.7276887871854	JUN/FOS/FOSB	5.1734452590886
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	5/38	248/9376	4.97453310696095	JUN/FOS/RHOB/NFKBIA/HSP90AA1	4.0464543505349
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	4/38	157/9376	6.28628897083473	ZFP36L2/SERPINE1/HLA-B/ZFP36L1	4.26097827818034
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	4/38	157/9376	6.28628897083473	JUN/MT-CO3/FOS/MT-CO1	4.26097827818034
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	3/38	78/9376	9.48987854251012	JUN/FOS/NFKBIA	4.80291067140833
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	3/38	82/9376	9.02695763799743	HLA-B/HSP90AA1/B2M	4.6570088670437
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	3/38	90/9376	8.22456140350877	JUN/FOS/NFKBIA	4.3930778892735
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	3/38	91/9376	8.13418160786582	JUN/FOS/NFKBIA	4.36238914868541
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	3/38	93/9376	7.95925297113752	JUN/FOS/NFKBIA	4.30239642777903
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	3/38	101/9376	7.32881709223554	EGR1/JUN/SERPINE1	4.07921667119267
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	4/38	196/9376	5.03544575725027	JUN/FOS/HLA-B/NFKBIA	3.6420735411593
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	4/38	205/9376	4.81437740693196	JUN/HLA-B/NFKBIA/B2M	3.52243304618425
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	3/38	109/9376	6.79092225977788	JUN/FOS/NFKBIA	3.87919761377065
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	4/38	216/9376	4.56920077972709	JUN/FOS/NFKBIA/HSP90AA1	3.38532695826401
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	4/38	217/9376	4.54814455493573	JUN/KLF4/FOS/HSP90AA1	3.37332080029581
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	3/38	122/9376	6.06729939603106	JUN/FOS/NFKBIA	3.59370343166071
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	3/38	122/9376	6.06729939603106	JUNB/CSH1/FOS	3.59370343166071
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	3/38	130/9376	5.69392712550607	JUN/FOS/NFKBIA	3.43780766917827
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	2/38	49/9376	10.0708915145005	JUN/FOSB	4.06094891484841
Human Diseases	Infectious disease: viral	hsa05162	Measles	3/38	136/9376	5.44272445820434	JUN/FOS/NFKBIA	3.32914988975305
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	3/38	137/9376	5.40299654245102	JUN/FOS/NFKBIA	3.31166689107253
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	3/38	138/9376	5.36384439359268	MT-CO3/MT-ND1/MT-CO1	3.29435443156102
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	3/38	138/9376	5.36384439359268	JUN/FOS/NFKBIA	3.29435443156102
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	3/38	139/9376	5.32525558500568	JUN/FOS/HSP90AA1	3.2772095036886
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	3/38	140/9376	5.28721804511278	EGR1/SERPINE1/KLF2	3.26022917452345
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	4/38	268/9376	3.68263943440691	MT-CO3/DUSP1/MT-ND1/MT-CO1	2.84229199626242
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	4/38	275/9376	3.5888995215311	EGR1/MT-CO3/MT-ND1/MT-CO1	2.77963317711393
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	3/38	163/9376	4.541168873103	JUN/FOS/NFKBIA	2.90931272453363
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	3/38	174/9376	4.2540834845735	HSP90AA1/DNAJB1/PPP1R15A	2.76383875380984
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	2/38	71/9376	6.95033358042995	JUN/NFKBIA	3.21042701066247
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	3/38	180/9376	4.11228070175439	HLA-B/NFKBIA/B2M	2.68946584176601
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	3/38	187/9376	3.95834506051224	JUN/NFKBIA/HSP90AA1	2.6066697245677
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	2/38	78/9376	6.32658569500675	BTG2/BTG1	3.01336646320914
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	2/38	78/9376	6.32658569500675	JUN/FOS	3.01336646320914
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	3/38	200/9376	3.70105263157895	JUN/FOS/NFKBIA	2.46304214925864
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	2/38	87/9376	5.67211131276467	MT-CO3/MT-CO1	2.79279351817046
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	2/38	87/9376	5.67211131276467	JUN/FOS	2.79279351817046
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	2/38	88/9376	5.60765550239234	SERPINE1/CLU	2.77019751552439
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	3/38	205/9376	3.61078305519897	JUN/HLA-B/NFKBIA	2.41095925467104
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	3/38	205/9376	3.61078305519897	MT-CO3/MT-ND1/MT-CO1	2.41095925467104
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	2/38	93/9376	5.30616864742501	EGR1/JUN	2.66218869797273
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	2/38	95/9376	5.19445983379501	JUN/FOS	2.62114446567672
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	4/38	368/9376	2.68192219679634	MT-CO3/MT-ND1/FUS/MT-CO1	2.09974291441699
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	2/38	99/9376	4.9845826687932	JUN/FOS	2.54241921602268
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	2/38	99/9376	4.9845826687932	JUN/FOS	2.54241921602268
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	3/38	226/9376	3.27526781555659	JUN/FOS/NFKBIA	2.20864897400762
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	3/38	227/9376	3.26083932297705	HLA-B/NFKBIA/B2M	2.19961318763959
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	2/38	105/9376	4.69974937343358	JUN/NFKBIA	2.43194733593731
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	2/38	106/9376	4.65541211519364	NFKBIA/HSP90AA1	2.4143482525314
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	3/38	235/9376	3.1498320268757	MT-CO3/MT-ND1/MT-CO1	2.12908062016465
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	4/38	388/9376	2.54367878459034	MT-CO3/MT-ND1/APOE/MT-CO1	1.98103326493469
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	2/38	115/9376	4.29107551487414	EGR1/FOS	2.26520925433231
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	2/38	120/9376	4.11228070175439	JUN/NFKBIA	2.18881074280157
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	2/38	148/9376	3.33428165007112	JUN/FOS	1.82591611888111
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	3/38	300/9376	2.46736842105263	JUN/DUSP1/FOS	1.64779451896793
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	4/38	480/9376	2.05614035087719	MT-CO3/MT-ND1/FUS/MT-CO1	1.51528864520729
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	3/38	308/9376	2.40328092959672	MT-CO3/MT-ND1/MT-CO1	1.59740385243473
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	2/38	154/9376	3.20437457279563	JUN/FOS	1.75947741304019
Organismal Systems	Environmental adaptation	hsa04710	Circadian rhythm	1/38	34/9376	7.25696594427245	BHLHE40	2.33149141125672
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	2/38	160/9376	3.08421052631579	VCAN/HLA-B	1.69621478722169
Human Diseases	Immune disease	hsa05330	Allograft rejection	1/38	39/9376	6.32658569500675	HLA-B	2.12631716074797
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	2/38	173/9376	2.85244904167934	NFKBIA/DNAJB1	1.56875496101173
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	1/38	44/9376	5.60765550239234	HLA-B	1.95420210117795
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	1/38	45/9376	5.48304093567251	HLA-B	1.92293838349497
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	1/38	52/9376	4.74493927125506	APOE	1.7274115559134
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	2/38	201/9376	2.45509295627128	NFKBIZ/FUS	1.33025908117587
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	1/38	54/9376	4.56920077972709	HLA-B	1.67789125870586
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	1/38	56/9376	4.40601503759398	NFKBIA	1.63073397732728
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	1/38	63/9376	3.91645781119465	PTGDS	1.48160240180782
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	1/38	66/9376	3.7384370015949	JUN	1.42413245335304
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/38	70/9376	3.52481203007519	NFKBIA	1.35253044109067
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	1/38	70/9376	3.52481203007519	JUN	1.35253044109067
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	1/38	70/9376	3.52481203007519	HLA-B	1.35253044109067
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	1/38	71/9376	3.47516679021497	FOS	1.33544484721589
Organismal Systems	Immune system	hsa04622	RIG-I-like receptor signaling pathway	1/38	72/9376	3.42690058479532	NFKBIA	1.31866319668102
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	1/38	75/9376	3.28982456140351	SERPINE1	1.27004327926916
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/38	77/9376	3.20437457279563	NFKBIA	1.23897668319039
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	2/38	253/9376	1.95048887039734	JUN/NFKBIA	0.977662507730579
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	1/38	83/9376	2.97273303741281	NFKBIA	1.15154230376958
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/38	86/9376	2.86903304773562	JUN	1.11073089222603
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/38	93/9376	2.65308432371251	NFKBIA	1.02198096816643
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	1/38	97/9376	2.54367878459034	FOS	0.974861046045463
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	1/38	103/9376	2.39550332141032	FUS	0.908426633824655
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	1/38	105/9376	2.34987468671679	NFKBIA	0.887309873415416
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	1/38	105/9376	2.34987468671679	JUN	0.887309873415416
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	1/38	109/9376	2.2636407532593	NFKBIA	0.846482127510864
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	1/38	110/9376	2.24306220095694	SERPINE1	0.836553184898411
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	1/38	110/9376	2.24306220095694	HSP90AA1	0.836553184898411
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	1/38	112/9376	2.20300751879699	NFKBIA	0.817012275020822
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	1/38	115/9376	2.14553775743707	FOS	0.78846040378164
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	1/38	115/9376	2.14553775743707	DUSP1	0.78846040378164
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	1/38	133/9376	1.85516422635536	KLF2	0.633606130487384
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	1/38	133/9376	1.85516422635536	HLA-B	0.633606130487384
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	1/38	133/9376	1.85516422635536	FOS	0.633606130487384
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	2/38	362/9376	1.36318697295725	CSH1/HSP90AA1	0.449548209917633
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	1/38	144/9376	1.71345029239766	KLF4	0.550360897409071
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	1/38	144/9376	1.71345029239766	NFKBIA	0.550360897409071
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	1/38	149/9376	1.65595196043801	MT-ND1	0.514855563406842
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	1/38	155/9376	1.5918505942275	HLA-B	0.473957530283837
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	1/38	156/9376	1.58164642375169	NFKBIA	0.467311428872456
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	1/38	157/9376	1.57157224270868	SERPINE1	0.46071202766805
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/38	168/9376	1.46867167919799	HSP90AA1	0.391013001349068
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	1/38	168/9376	1.46867167919799	CSH1	0.391013001349068
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	1/38	170/9376	1.45139318885449	JUN	0.378873717059309
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	1/38	178/9376	1.38616203429923	JUN	0.331805342094942
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/38	184/9376	1.34096109839817	SEMA4A	0.297960872154386
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/38	191/9376	1.29181592725269	FOSB	0.25991814384653
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	1/38	193/9376	1.27842923370603	NFKBIA	0.24931688733342
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	1/38	203/9376	1.21545242416386	JUN	0.197967641369585
NA	NA	hsa04081	Hormone signaling	1/38	219/9376	1.126652247056	CSH1	0.120978682744658
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	1/38	233/9376	1.05895640388525	VCAN	0.058131976283687
Genetic Information Processing	Transcription	hsa03040	Spliceosome	1/38	243/9376	1.01537795105047	FUS	0.0154933518553519
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	1/38	250/9376	0.986947368421053	HLA-B	-0.0133437640412905
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	1/38	298/9376	0.827975980219004	CSH1	-0.192509708498469
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	1/38	333/9376	0.740951477793583	HLA-B	-0.307041777906982
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	1/38	370/9376	0.666856330014225	CSH1	-0.417077688682147
NA	NA	hsa04519	Cadherin signaling	1/38	404/9376	0.610734757686295	NFKBIA	-0.510202026047573