ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 65/420 175/18639 0.371428571428571 16.4834693877551 5.43880949730811e-62 4.04103545649993e-59 GO:0019843 rRNA binding 16/420 65/18639 0.246153846153846 10.923956043956 7.85704932892928e-13 2.91889382569723e-10 GO:1990948 ubiquitin ligase inhibitor activity 7/420 11/18639 0.636363636363636 28.2409090909091 8.5694301877781e-10 2.12236220983971e-07 GO:0055105 ubiquitin-protein transferase inhibitor activity 7/420 15/18639 0.466666666666667 20.71 1.54530112061623e-08 2.87039683154464e-06 GO:0045296 cadherin binding 24/420 334/18639 0.0718562874251497 3.18887938408897 6.45846655671485e-07 9.59728130327827e-05 GO:0004857 enzyme inhibitor activity 27/420 416/18639 0.0649038461538462 2.88033997252747 9.53734633499427e-07 0.000118104138781679 GO:0016860 intramolecular oxidoreductase activity 9/420 53/18639 0.169811320754717 7.53598382749326 2.53228762052682e-06 0.000268784243150204 GO:0044389 ubiquitin-like protein ligase binding 22/420 322/18639 0.0683229813664596 3.03207630878438 4.31121894360335e-06 0.000400404459387161 GO:0031625 ubiquitin protein ligase binding 21/420 302/18639 0.0695364238410596 3.08592715231788 5.42205343839317e-06 0.000447620633858459 GO:0005201 extracellular matrix structural constituent 15/420 168/18639 0.0892857142857143 3.96237244897959 6.37266334426845e-06 0.000473488886479145 GO:0048027 mRNA 5'-UTR binding 6/420 24/18639 0.25 11.0946428571429 1.20482054855522e-05 0.000813801515978662 GO:0055106 ubiquitin-protein transferase regulator activity 7/420 36/18639 0.194444444444444 8.62916666666667 1.33138538931652e-05 0.000824349453551813 GO:0016853 isomerase activity 15/420 180/18639 0.0833333333333333 3.69821428571429 1.46703456758385e-05 0.000838466679780614 GO:0008135 translation factor activity, RNA binding 10/420 83/18639 0.120481927710843 5.34681583476764 1.70147906455564e-05 0.000902999246403458 GO:0180051 translation factor activity 10/420 84/18639 0.119047619047619 5.28316326530612 1.89316444558633e-05 0.000937747455380429 GO:0098641 cadherin binding involved in cell-cell adhesion 5/420 18/18639 0.277777777777778 12.327380952381 3.81437428015188e-05 0.00177130005634553 GO:0015035 protein-disulfide reductase activity 6/420 34/18639 0.176470588235294 7.83151260504202 9.94914318742055e-05 0.00434836081661969 GO:0043022 ribosome binding 10/420 112/18639 0.0892857142857143 3.96237244897959 0.000221972556674914 0.00916253386719229 GO:0015036 disulfide oxidoreductase activity 6/420 40/18639 0.15 6.65678571428571 0.00025335320251724 0.00990744365633209 GO:0031386 protein tag activity 4/420 15/18639 0.266666666666667 11.8342857142857 0.000284829105415934 0.0100775250154304 GO:0141047 molecular tag activity 4/420 15/18639 0.266666666666667 11.8342857142857 0.000284829105415934 0.0100775250154304 GO:0003746 translation elongation factor activity 4/420 18/18639 0.222222222222222 9.86190476190476 0.000605204963240875 0.020439422167635 GO:0043021 ribonucleoprotein complex binding 12/420 177/18639 0.0677966101694915 3.00871670702179 0.000698384476455928 0.0223804397512993 GO:0003756 protein disulfide isomerase activity 4/420 19/18639 0.210526315789474 9.34285714285714 0.00075304306027252 0.0223804397512993 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 4/420 19/18639 0.210526315789474 9.34285714285714 0.00075304306027252 0.0223804397512993 GO:0043024 ribosomal small subunit binding 4/420 20/18639 0.2 8.87571428571429 0.000924678565270228 0.0264244682306069 GO:0003743 translation initiation factor activity 6/420 51/18639 0.117647058823529 5.22100840336134 0.000965220756926271 0.0265614452739341 GO:0002020 protease binding 10/420 136/18639 0.0735294117647059 3.26313025210084 0.00103530563818578 0.027472574613287 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 5/420 36/18639 0.138888888888889 6.16369047619048 0.00120247837388358 0.0288206913482418 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 5/420 36/18639 0.138888888888889 6.16369047619048 0.00120247837388358 0.0288206913482418 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 5/420 36/18639 0.138888888888889 6.16369047619048 0.00120247837388358 0.0288206913482418 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 6/420 54/18639 0.111111111111111 4.93095238095238 0.00130800474003837 0.0303702350577658 GO:0030414 peptidase inhibitor activity 11/420 169/18639 0.0650887573964497 2.8885460693153 0.00160068305993204 0.0360396216221063 GO:0051082 unfolded protein binding 9/420 121/18639 0.0743801652892562 3.30088547815821 0.00168372168597711 0.0367942709612057 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 5/420 39/18639 0.128205128205128 5.68956043956044 0.00173777553472107 0.0368904920656502 GO:0061134 peptidase regulator activity 13/420 226/18639 0.0575221238938053 2.55274968394437 0.00192051166626157 0.0396372268897874 GO:0097371 MDM2/MDM4 family protein binding 3/420 12/18639 0.25 11.0946428571429 0.00214786839496473 0.0431315193907781 GO:0016859 cis-trans isomerase activity 5/420 42/18639 0.119047619047619 5.28316326530612 0.00242977434409292 0.0475084825700273 GO:0050750 low-density lipoprotein particle receptor binding 4/420 26/18639 0.153846153846154 6.82747252747253 0.00256466699742574 0.0488601943355725 GO:0023026 MHC class II protein complex binding 4/420 27/18639 0.148148148148148 6.57460317460317 0.00295781115511297 0.0541878264439352 GO:0001046 core promoter sequence-specific DNA binding 5/420 44/18639 0.113636363636364 5.04301948051948 0.00299017615639481 0.0541878264439352 GO:0042605 peptide antigen binding 5/420 45/18639 0.111111111111111 4.93095238095238 0.00330282375810929 0.0584285250541714 GO:0044548 S100 protein binding 3/420 14/18639 0.214285714285714 9.50969387755102 0.00343671036774955 0.0586156690767383 GO:0005539 glycosaminoglycan binding 13/420 242/18639 0.0537190082644628 2.38397284533648 0.00347118363307737 0.0586156690767383 GO:0004866 endopeptidase inhibitor activity 10/420 161/18639 0.062111801242236 2.7564330079858 0.00360432113712465 0.0595113467751914 GO:0019838 growth factor binding 9/420 136/18639 0.0661764705882353 2.93681722689076 0.00371948186239712 0.0600777179078491 GO:0043236 laminin binding 4/420 29/18639 0.137931034482759 6.12118226600985 0.00386367739767086 0.0607093216758475 GO:0050840 extracellular matrix binding 6/420 67/18639 0.0895522388059701 3.97420042643923 0.00395786611035045 0.0607093216758475 GO:0033218 amide binding 13/420 247/18639 0.0526315789473684 2.33571428571429 0.00412455841234528 0.0607093216758475 GO:0005523 tropomyosin binding 3/420 15/18639 0.2 8.87571428571429 0.00422468068333296 0.0607093216758475 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 3/420 15/18639 0.2 8.87571428571429 0.00422468068333296 0.0607093216758475 GO:1990841 promoter-specific chromatin binding 6/420 68/18639 0.0882352941176471 3.91575630252101 0.00426026986524504 0.0607093216758475 GO:0035925 mRNA 3'-UTR AU-rich region binding 4/420 30/18639 0.133333333333333 5.91714285714286 0.00437996782601158 0.0607093216758475 GO:0042277 peptide binding 13/420 249/18639 0.0522088353413655 2.31695352839931 0.00441225218101718 0.0607093216758475 GO:0070325 lipoprotein particle receptor binding 4/420 31/18639 0.129032258064516 5.72626728110599 0.00494079990623576 0.0666551800530988 GO:0005521 lamin binding 3/420 16/18639 0.1875 8.32098214285714 0.00511351986948402 0.0666551800530988 GO:0043023 ribosomal large subunit binding 3/420 16/18639 0.1875 8.32098214285714 0.00511351986948402 0.0666551800530988 GO:0051059 NF-kappaB binding 4/420 32/18639 0.125 5.54732142857143 0.00554783983780626 0.0710697413705181 GO:0004867 serine-type endopeptidase inhibitor activity 7/420 95/18639 0.0736842105263158 3.27 0.00566499094769468 0.0713404792226635 GO:0071889 14-3-3 protein binding 4/420 33/18639 0.121212121212121 5.37922077922078 0.00620270133532641 0.0768101182024588 GO:0098631 cell adhesion mediator activity 6/420 76/18639 0.0789473684210526 3.50357142857143 0.00732669046612136 0.0892414920709536 GO:0098632 cell-cell adhesion mediator activity 5/420 55/18639 0.0909090909090909 4.03441558441558 0.00783343895053312 0.0923848434959699 GO:0140313 molecular sequestering activity 5/420 55/18639 0.0909090909090909 4.03441558441558 0.00783343895053312 0.0923848434959699 GO:0046332 SMAD binding 6/420 79/18639 0.0759493670886076 3.37052441229656 0.00880850191179396 0.102261201882233 GO:0061135 endopeptidase regulator activity 10/420 184/18639 0.0543478260869565 2.41187888198758 0.00904301221864042 0.103368585822305 GO:0023023 MHC protein complex binding 4/420 37/18639 0.108108108108108 4.7976833976834 0.00933067100505984 0.105040735708477 GO:0001540 amyloid-beta binding 6/420 83/18639 0.072289156626506 3.20808950086059 0.0111025526291233 0.122106577456194 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 3/420 21/18639 0.142857142857143 6.33979591836735 0.011175299148077 0.122106577456194 GO:0005200 structural constituent of cytoskeleton 7/420 112/18639 0.0625 2.77366071428571 0.0134542959154003 0.144877418335397 GO:0017134 fibroblast growth factor binding 3/420 23/18639 0.130434782608696 5.78850931677019 0.0143958357914045 0.152801514185908 GO:0005540 hyaluronic acid binding 3/420 24/18639 0.125 5.54732142857143 0.0161825645024107 0.166995075351266 GO:0050431 transforming growth factor beta binding 3/420 24/18639 0.125 5.54732142857143 0.0161825645024107 0.166995075351266 GO:0030547 signaling receptor inhibitor activity 4/420 44/18639 0.0909090909090909 4.03441558441558 0.0169653736416848 0.172674967339339 GO:0022853 active monoatomic ion transmembrane transporter activity 7/420 118/18639 0.0593220338983051 2.63262711864407 0.0174837279023769 0.175546078803595 GO:0043178 alcohol binding 6/420 92/18639 0.0652173913043478 2.89425465838509 0.017748304850099 0.175826540048314 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 5/420 68/18639 0.0735294117647059 3.26313025210084 0.0185410370665547 0.178908968057794 GO:0032934 sterol binding 5/420 68/18639 0.0735294117647059 3.26313025210084 0.0185410370665547 0.178908968057794 GO:0008143 poly(A) binding 3/420 26/18639 0.115384615384615 5.1206043956044 0.0201128497481032 0.181037123591234 GO:0070412 R-SMAD binding 3/420 26/18639 0.115384615384615 5.1206043956044 0.0201128497481032 0.181037123591234 GO:0004090 carbonyl reductase (NADPH) activity 2/420 10/18639 0.2 8.87571428571429 0.0202235279381863 0.181037123591234 GO:0004862 cAMP-dependent protein kinase inhibitor activity 2/420 10/18639 0.2 8.87571428571429 0.0202235279381863 0.181037123591234 GO:0005528 FK506 binding 2/420 10/18639 0.2 8.87571428571429 0.0202235279381863 0.181037123591234 GO:0098505 G-rich strand telomeric DNA binding 2/420 10/18639 0.2 8.87571428571429 0.0202235279381863 0.181037123591234 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 7/420 122/18639 0.0573770491803279 2.54631147540984 0.0206012920567235 0.182223333311257 GO:0140693 molecular condensate scaffold activity 4/420 48/18639 0.0833333333333333 3.69821428571429 0.0226795139255114 0.198245633490058 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 2/420 11/18639 0.181818181818182 8.06883116883117 0.0243536122779894 0.20331161710726 GO:0042608 T cell receptor binding 2/420 11/18639 0.181818181818182 8.06883116883117 0.0243536122779894 0.20331161710726 GO:0048185 activin binding 2/420 11/18639 0.181818181818182 8.06883116883117 0.0243536122779894 0.20331161710726 GO:0097493 structural molecule activity conferring elasticity 2/420 11/18639 0.181818181818182 8.06883116883117 0.0243536122779894 0.20331161710726 GO:0005525 GTP binding 15/420 378/18639 0.0396825396825397 1.76105442176871 0.0250500745980509 0.20680228251502 GO:0048029 monosaccharide binding 5/420 74/18639 0.0675675675675676 2.99855212355212 0.0257144243207094 0.209750073172192 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 7/420 128/18639 0.0546875 2.426953125 0.0259725872986141 0.209750073172192 GO:0003785 actin monomer binding 3/420 29/18639 0.103448275862069 4.59088669950739 0.0269048401588716 0.209750073172192 GO:0004859 phospholipase inhibitor activity 2/420 12/18639 0.166666666666667 7.39642857142857 0.0287947610545943 0.209750073172192 GO:0005025 transforming growth factor beta receptor activity, type I 2/420 12/18639 0.166666666666667 7.39642857142857 0.0287947610545943 0.209750073172192 GO:0005026 transforming growth factor beta receptor activity, type II 2/420 12/18639 0.166666666666667 7.39642857142857 0.0287947610545943 0.209750073172192 GO:0005527 macrolide binding 2/420 12/18639 0.166666666666667 7.39642857142857 0.0287947610545943 0.209750073172192 GO:0008603 cAMP-dependent protein kinase regulator activity 2/420 12/18639 0.166666666666667 7.39642857142857 0.0287947610545943 0.209750073172192 GO:0016361 activin receptor activity, type I 2/420 12/18639 0.166666666666667 7.39642857142857 0.0287947610545943 0.209750073172192 GO:0016362 activin receptor activity, type II 2/420 12/18639 0.166666666666667 7.39642857142857 0.0287947610545943 0.209750073172192 GO:0017002 activin receptor activity 2/420 12/18639 0.166666666666667 7.39642857142857 0.0287947610545943 0.209750073172192 GO:0043047 single-stranded telomeric DNA binding 2/420 12/18639 0.166666666666667 7.39642857142857 0.0287947610545943 0.209750073172192 GO:0016769 transferase activity, transferring nitrogenous groups 3/420 30/18639 0.1 4.43785714285714 0.0294076037514116 0.210094707570181 GO:0048019 receptor antagonist activity 3/420 30/18639 0.1 4.43785714285714 0.0294076037514116 0.210094707570181 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 7/420 132/18639 0.053030303030303 2.35340909090909 0.0300421422217373 0.212583920673817 GO:0015485 cholesterol binding 4/420 54/18639 0.0740740740740741 3.28730158730159 0.0332156408212679 0.230680370420189 GO:0039706 co-receptor binding 2/420 13/18639 0.153846153846154 6.82747252747253 0.0335309286748054 0.230680370420189 GO:0070123 transforming growth factor beta receptor activity, type III 2/420 13/18639 0.153846153846154 6.82747252747253 0.0335309286748054 0.230680370420189 GO:0000049 tRNA binding 5/420 80/18639 0.0625 2.77366071428571 0.0344559123449594 0.232729570351609 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 3/420 32/18639 0.09375 4.16049107142857 0.0347684822463373 0.232729570351609 GO:0070717 poly-purine tract binding 3/420 32/18639 0.09375 4.16049107142857 0.0347684822463373 0.232729570351609 GO:0005496 steroid binding 6/420 108/18639 0.0555555555555556 2.46547619047619 0.0354626843112334 0.235256914671843 GO:0019001 guanyl nucleotide binding 15/420 400/18639 0.0375 1.66419642857143 0.0383497279225662 0.246897822175898 GO:0032561 guanyl ribonucleotide binding 15/420 400/18639 0.0375 1.66419642857143 0.0383497279225662 0.246897822175898 GO:0098821 BMP receptor activity 2/420 14/18639 0.142857142857143 6.33979591836735 0.0385466317259814 0.246897822175898 GO:0098847 sequence-specific single stranded DNA binding 2/420 14/18639 0.142857142857143 6.33979591836735 0.0385466317259814 0.246897822175898 GO:0008201 heparin binding 8/420 172/18639 0.0465116279069767 2.0641196013289 0.0413972261092887 0.261846897993897 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 4/420 58/18639 0.0689655172413793 3.06059113300493 0.0415853754552892 0.261846897993897 GO:0016229 steroid dehydrogenase activity 3/420 35/18639 0.0857142857142857 3.80387755102041 0.0436855045695864 0.267038113762841 GO:0004129 cytochrome-c oxidase activity 2/420 15/18639 0.133333333333333 5.91714285714286 0.0438269318863888 0.267038113762841 GO:0031005 filamin binding 2/420 15/18639 0.133333333333333 5.91714285714286 0.0438269318863888 0.267038113762841 GO:0070063 RNA polymerase binding 4/420 59/18639 0.0677966101694915 3.00871670702179 0.043847442636698 0.267038113762841 GO:0001221 transcription coregulator binding 6/420 115/18639 0.0521739130434783 2.31540372670807 0.0458707104173731 0.277088925529335 GO:0009055 electron transfer activity 6/420 116/18639 0.0517241379310345 2.29544334975369 0.0474969209127907 0.279943225593968 GO:0019208 phosphatase regulator activity 6/420 117/18639 0.0512820512820513 2.27582417582418 0.049158400125601 0.279943225593968 GO:0005024 transforming growth factor beta receptor activity 2/420 16/18639 0.125 5.54732142857143 0.0493574193173753 0.279943225593968 GO:0016675 oxidoreductase activity, acting on a heme group of donors 2/420 16/18639 0.125 5.54732142857143 0.0493574193173753 0.279943225593968 GO:0016722 oxidoreductase activity, acting on metal ions 2/420 16/18639 0.125 5.54732142857143 0.0493574193173753 0.279943225593968 GO:0019841 retinol binding 2/420 16/18639 0.125 5.54732142857143 0.0493574193173753 0.279943225593968 GO:0022841 potassium ion leak channel activity 2/420 16/18639 0.125 5.54732142857143 0.0493574193173753 0.279943225593968 GO:0055102 lipase inhibitor activity 2/420 16/18639 0.125 5.54732142857143 0.0493574193173753 0.279943225593968 GO:0003727 single-stranded RNA binding 5/420 89/18639 0.0561797752808989 2.49317817014446 0.0506585520008931 0.285146243459572 GO:0030246 carbohydrate binding 11/420 280/18639 0.0392857142857143 1.74344387755102 0.053271814666448 0.295138134883958 GO:0005501 retinoid binding 3/420 38/18639 0.0789473684210526 3.50357142857143 0.0536253677110825 0.295138134883958 GO:0019840 isoprenoid binding 3/420 38/18639 0.0789473684210526 3.50357142857143 0.0536253677110825 0.295138134883958 GO:0070492 oligosaccharide binding 2/420 17/18639 0.117647058823529 5.22100840336134 0.055124196524405 0.301156456012007 GO:0016776 phosphotransferase activity, phosphate group as acceptor 3/420 39/18639 0.0769230769230769 3.41373626373626 0.0571592050805472 0.309994812955084 GO:0015078 proton transmembrane transporter activity 8/420 185/18639 0.0432432432432432 1.91907335907336 0.0587171660621078 0.316136625972073 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/420 18/18639 0.111111111111111 4.93095238095238 0.0611138626743388 0.32321546657174 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 2/420 18/18639 0.111111111111111 4.93095238095238 0.0611138626743388 0.32321546657174 GO:0019207 kinase regulator activity 11/420 287/18639 0.0383275261324042 1.70092085614734 0.0613369862538564 0.32321546657174 GO:0008137 NADH dehydrogenase (ubiquinone) activity 3/420 41/18639 0.0731707317073171 3.24721254355401 0.0645476104708754 0.337738553379299 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 2/420 19/18639 0.105263157894737 4.67142857142857 0.0673134983566658 0.342561159445224 GO:0016918 retinal binding 2/420 19/18639 0.105263157894737 4.67142857142857 0.0673134983566658 0.342561159445224 GO:0022840 leak channel activity 2/420 19/18639 0.105263157894737 4.67142857142857 0.0673134983566658 0.342561159445224 GO:0022842 narrow pore channel activity 2/420 19/18639 0.105263157894737 4.67142857142857 0.0673134983566658 0.342561159445224 GO:0035198 miRNA binding 3/420 42/18639 0.0714285714285714 3.16989795918367 0.0683985018013946 0.343378965124569 GO:0042056 chemoattractant activity 3/420 42/18639 0.0714285714285714 3.16989795918367 0.0683985018013946 0.343378965124569 GO:0003924 GTPase activity 12/420 331/18639 0.0362537764350453 1.60889080707812 0.0727217282772285 0.36263251080524 GO:0031418 L-ascorbic acid binding 2/420 20/18639 0.1 4.43785714285714 0.0737106507767179 0.365113423514009 GO:0008083 growth factor activity 7/420 162/18639 0.0432098765432099 1.91759259259259 0.0743474147164235 0.365828669763594 GO:0031072 heat shock protein binding 6/420 131/18639 0.0458015267175573 2.03260632497274 0.0761588058634841 0.371033311254287 GO:0003954 NADH dehydrogenase activity 3/420 44/18639 0.0681818181818182 3.02581168831169 0.0764038985489986 0.371033311254287 GO:0015399 primary active transmembrane transporter activity 7/420 166/18639 0.0421686746987952 1.87138554216867 0.0821849152772633 0.396515532798744 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 10/420 268/18639 0.0373134328358209 1.65591684434968 0.0827636822935264 0.396731715768323 GO:0030291 protein serine/threonine kinase inhibitor activity 3/420 46/18639 0.0652173913043478 2.89425465838509 0.0848003308420684 0.403888755228569 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/420 22/18639 0.0909090909090909 4.03441558441558 0.0870499418207294 0.409885434923375 GO:0140297 DNA-binding transcription factor binding 16/420 488/18639 0.0327868852459016 1.45503512880562 0.0871627169823597 0.409885434923375 GO:0017022 myosin binding 4/420 76/18639 0.0526315789473684 2.33571428571429 0.0924423068350281 0.430219912505296 GO:0004602 glutathione peroxidase activity 2/420 23/18639 0.0869565217391304 3.85900621118012 0.0939693804901889 0.430219912505296 GO:0005283 amino acid:sodium symporter activity 2/420 23/18639 0.0869565217391304 3.85900621118012 0.0939693804901889 0.430219912505296 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 2/420 23/18639 0.0869565217391304 3.85900621118012 0.0939693804901889 0.430219912505296 GO:0019888 protein phosphatase regulator activity 5/420 107/18639 0.0467289719626168 2.0737650200267 0.0943820265657647 0.430219912505296 GO:0001217 DNA-binding transcription repressor activity 10/420 278/18639 0.0359712230215827 1.59635149023638 0.0992804382087711 0.447407856040546 GO:0019199 transmembrane receptor protein kinase activity 4/420 78/18639 0.0512820512820513 2.27582417582418 0.0993570608972949 0.447407856040546 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 2/420 24/18639 0.0833333333333333 3.69821428571429 0.10104090921635 0.44954129070508 GO:0035035 histone acetyltransferase binding 2/420 24/18639 0.0833333333333333 3.69821428571429 0.10104090921635 0.44954129070508 GO:0048306 calcium-dependent protein binding 4/420 80/18639 0.05 2.21892857142857 0.106504585919745 0.462995956336192 GO:0019955 cytokine binding 6/420 144/18639 0.0416666666666667 1.84910714285714 0.107430146099762 0.462995956336192 GO:0001848 complement binding 2/420 25/18639 0.08 3.55028571428571 0.108254200502058 0.462995956336192 GO:0005537 D-mannose binding 2/420 25/18639 0.08 3.55028571428571 0.108254200502058 0.462995956336192 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 2/420 25/18639 0.08 3.55028571428571 0.108254200502058 0.462995956336192 GO:0019211 phosphatase activator activity 2/420 25/18639 0.08 3.55028571428571 0.108254200502058 0.462995956336192 GO:0005319 lipid transporter activity 7/420 178/18639 0.0393258426966292 1.74522471910112 0.108427047648045 0.462995956336192 GO:0008198 ferrous iron binding 2/420 26/18639 0.0769230769230769 3.41373626373626 0.115599313064887 0.488013009131883 GO:0019865 immunoglobulin binding 2/420 26/18639 0.0769230769230769 3.41373626373626 0.115599313064887 0.488013009131883 GO:0004864 protein phosphatase inhibitor activity 3/420 53/18639 0.0566037735849057 2.51199460916442 0.117011399195476 0.488423986529432 GO:0140296 general transcription initiation factor binding 3/420 53/18639 0.0566037735849057 2.51199460916442 0.117011399195476 0.488423986529432 GO:0019209 kinase activator activity 6/420 148/18639 0.0405405405405405 1.79913127413127 0.118206882571997 0.490657618720637 GO:0004860 protein kinase inhibitor activity 4/420 84/18639 0.0476190476190476 2.11326530612245 0.121469744506816 0.50140011204758 GO:0005044 scavenger receptor activity 2/420 27/18639 0.0740740740740741 3.28730158730159 0.1230666797443 0.502409577197885 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 2/420 27/18639 0.0740740740740741 3.28730158730159 0.1230666797443 0.502409577197885 GO:0019887 protein kinase regulator activity 9/420 255/18639 0.0352941176470588 1.5663025210084 0.123773492158957 0.502533905322977 GO:0003713 transcription coactivator activity 9/420 256/18639 0.03515625 1.56018415178571 0.125903120092894 0.508402272983805 GO:0016209 antioxidant activity 4/420 86/18639 0.0465116279069767 2.0641196013289 0.129272357693813 0.519185739278394 GO:0097718 disordered domain specific binding 2/420 28/18639 0.0714285714285714 3.16989795918367 0.130647095755603 0.521762492654724 GO:0019212 phosphatase inhibitor activity 3/420 56/18639 0.0535714285714286 2.37742346938776 0.132020657629997 0.521762492654724 GO:0170055 lipid transmembrane transporter activity 3/420 56/18639 0.0535714285714286 2.37742346938776 0.132020657629997 0.521762492654724 GO:0016651 oxidoreductase activity, acting on NAD(P)H 4/420 88/18639 0.0454545454545455 2.01720779220779 0.137277782785881 0.539668743967775 GO:0005416 amino acid:monoatomic cation symporter activity 2/420 29/18639 0.0689655172413793 3.06059113300493 0.138331707281286 0.540949781631557 GO:0003730 mRNA 3'-UTR binding 9/420 262/18639 0.0343511450381679 1.52445474372955 0.13908793503068 0.541059349360186 GO:0061980 regulatory RNA binding 3/420 58/18639 0.0517241379310345 2.29544334975369 0.142380268255669 0.550981975593554 GO:0019210 kinase inhibitor activity 4/420 90/18639 0.0444444444444444 1.97238095238095 0.145477772831203 0.559593898403033 GO:0008106 alcohol dehydrogenase (NADP+) activity 2/420 30/18639 0.0666666666666667 2.95857142857143 0.146112000390563 0.559593898403033 GO:0070888 E-box binding 3/420 59/18639 0.0508474576271186 2.25653753026634 0.147658812485257 0.5626179368028 GO:0072341 modified amino acid binding 4/420 91/18639 0.043956043956044 1.95070643642072 0.149648089733964 0.56728842179763 GO:0008327 methyl-CpG binding 2/420 31/18639 0.0645161290322581 2.863133640553 0.153979790278151 0.577813051397305 GO:0017147 Wnt-protein binding 2/420 31/18639 0.0645161290322581 2.863133640553 0.153979790278151 0.577813051397305 GO:0051213 dioxygenase activity 4/420 93/18639 0.043010752688172 1.90875576036866 0.158123979474956 0.590382496230616 GO:0031369 translation initiation factor binding 2/420 32/18639 0.0625 2.77366071428571 0.161927210813605 0.59266954499758 GO:0071813 lipoprotein particle binding 2/420 32/18639 0.0625 2.77366071428571 0.161927210813605 0.59266954499758 GO:0071814 protein-lipid complex binding 2/420 32/18639 0.0625 2.77366071428571 0.161927210813605 0.59266954499758 GO:0120015 sterol transfer activity 2/420 32/18639 0.0625 2.77366071428571 0.161927210813605 0.59266954499758 GO:0031490 chromatin DNA binding 5/420 128/18639 0.0390625 1.73353794642857 0.162978677719039 0.593593909535519 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 11/420 349/18639 0.0315186246418338 1.39875153499795 0.166553782093935 0.60365590290631 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 2/420 33/18639 0.0606060606060606 2.68961038961039 0.169946704392713 0.607096425649366 GO:0140311 protein sequestering activity 2/420 33/18639 0.0606060606060606 2.68961038961039 0.169946704392713 0.607096425649366 GO:1901681 sulfur compound binding 9/420 275/18639 0.0327272727272727 1.45238961038961 0.16995431565958 0.607096425649366 GO:0016831 carboxy-lyase activity 2/420 34/18639 0.0588235294117647 2.61050420168067 0.178031012082697 0.629890676083064 GO:0030332 cyclin binding 2/420 34/18639 0.0588235294117647 2.61050420168067 0.178031012082697 0.629890676083064 GO:0051087 protein-folding chaperone binding 5/420 134/18639 0.0373134328358209 1.65591684434968 0.185495822585965 0.652484249488296 GO:0005343 organic acid:sodium symporter activity 2/420 35/18639 0.0571428571428571 2.53591836734694 0.186173164053188 0.652484249488296 GO:0004033 aldo-keto reductase (NADPH) activity 2/420 36/18639 0.0555555555555556 2.46547619047619 0.194366470285146 0.652846046967468 GO:0015171 amino acid transmembrane transporter activity 4/420 102/18639 0.0392156862745098 1.74033613445378 0.198277637738391 0.652846046967468 GO:0030280 structural constituent of skin epidermis 2/420 37/18639 0.0540540540540541 2.3988416988417 0.202604511550093 0.652846046967468 GO:0002039 p53 binding 3/420 69/18639 0.0434782608695652 1.92950310559006 0.203490425958727 0.652846046967468 GO:0001094 TFIID-class transcription factor complex binding 1/420 10/18639 0.1 4.43785714285714 0.203849640506666 0.652846046967468 GO:0004382 GDP phosphatase activity 1/420 10/18639 0.1 4.43785714285714 0.203849640506666 0.652846046967468 GO:0005131 growth hormone receptor binding 1/420 10/18639 0.1 4.43785714285714 0.203849640506666 0.652846046967468 GO:0008190 eukaryotic initiation factor 4E binding 1/420 10/18639 0.1 4.43785714285714 0.203849640506666 0.652846046967468 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 1/420 10/18639 0.1 4.43785714285714 0.203849640506666 0.652846046967468 GO:0016868 intramolecular phosphotransferase activity 1/420 10/18639 0.1 4.43785714285714 0.203849640506666 0.652846046967468 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/420 10/18639 0.1 4.43785714285714 0.203849640506666 0.652846046967468 GO:0019911 structural constituent of myelin sheath 1/420 10/18639 0.1 4.43785714285714 0.203849640506666 0.652846046967468 GO:0030957 Tat protein binding 1/420 10/18639 0.1 4.43785714285714 0.203849640506666 0.652846046967468 GO:0032356 oxidized DNA binding 1/420 10/18639 0.1 4.43785714285714 0.203849640506666 0.652846046967468 GO:0035256 G protein-coupled glutamate receptor binding 1/420 10/18639 0.1 4.43785714285714 0.203849640506666 0.652846046967468 GO:0035374 chondroitin sulfate binding 1/420 10/18639 0.1 4.43785714285714 0.203849640506666 0.652846046967468 GO:0043295 glutathione binding 1/420 10/18639 0.1 4.43785714285714 0.203849640506666 0.652846046967468 GO:0043422 protein kinase B binding 1/420 10/18639 0.1 4.43785714285714 0.203849640506666 0.652846046967468 GO:0051880 G-quadruplex DNA binding 1/420 10/18639 0.1 4.43785714285714 0.203849640506666 0.652846046967468 GO:0097177 mitochondrial ribosome binding 1/420 10/18639 0.1 4.43785714285714 0.203849640506666 0.652846046967468 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 14/420 484/18639 0.0289256198347107 1.28367768595041 0.205350139171159 0.654828984567259 GO:0008028 monocarboxylic acid transmembrane transporter activity 3/420 70/18639 0.0428571428571429 1.9019387755102 0.209326225943399 0.659187351175373 GO:0042162 telomeric DNA binding 2/420 38/18639 0.0526315789473684 2.33571428571429 0.21088113065226 0.659187351175373 GO:0008013 beta-catenin binding 4/420 106/18639 0.0377358490566038 1.67466307277628 0.217033586893426 0.659187351175373 GO:0001216 DNA-binding transcription activator activity 14/420 491/18639 0.0285132382892057 1.26537678207739 0.220100297897568 0.659187351175373 GO:0005518 collagen binding 3/420 72/18639 0.0416666666666667 1.84910714285714 0.221105802949034 0.659187351175373 GO:0005536 D-glucose binding 1/420 11/18639 0.0909090909090909 4.03441558441558 0.221799243329533 0.659187351175373 GO:0008199 ferric iron binding 1/420 11/18639 0.0909090909090909 4.03441558441558 0.221799243329533 0.659187351175373 GO:0015173 aromatic amino acid transmembrane transporter activity 1/420 11/18639 0.0909090909090909 4.03441558441558 0.221799243329533 0.659187351175373 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/420 11/18639 0.0909090909090909 4.03441558441558 0.221799243329533 0.659187351175373 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/420 11/18639 0.0909090909090909 4.03441558441558 0.221799243329533 0.659187351175373 GO:0019215 intermediate filament binding 1/420 11/18639 0.0909090909090909 4.03441558441558 0.221799243329533 0.659187351175373 GO:0019864 IgG binding 1/420 11/18639 0.0909090909090909 4.03441558441558 0.221799243329533 0.659187351175373 GO:0034713 type I transforming growth factor beta receptor binding 1/420 11/18639 0.0909090909090909 4.03441558441558 0.221799243329533 0.659187351175373 GO:0048407 platelet-derived growth factor binding 1/420 11/18639 0.0909090909090909 4.03441558441558 0.221799243329533 0.659187351175373 GO:0050998 nitric-oxide synthase binding 1/420 11/18639 0.0909090909090909 4.03441558441558 0.221799243329533 0.659187351175373 GO:0180030 inositol phosphate kinase activity 1/420 11/18639 0.0909090909090909 4.03441558441558 0.221799243329533 0.659187351175373 GO:1900750 oligopeptide binding 1/420 11/18639 0.0909090909090909 4.03441558441558 0.221799243329533 0.659187351175373 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 2/420 40/18639 0.05 2.21892857142857 0.227526732984288 0.663557512232888 GO:0071949 FAD binding 2/420 40/18639 0.05 2.21892857142857 0.227526732984288 0.663557512232888 GO:0140662 ATP-dependent protein folding chaperone 2/420 40/18639 0.05 2.21892857142857 0.227526732984288 0.663557512232888 GO:0022804 active transmembrane transporter activity 13/420 457/18639 0.0284463894967177 1.26241012816505 0.233344946560106 0.663557512232888 GO:0042287 MHC protein binding 2/420 41/18639 0.0487804878048781 2.16480836236934 0.235884636702925 0.663557512232888 GO:0005165 neurotrophin receptor binding 1/420 12/18639 0.0833333333333333 3.69821428571429 0.239345105354528 0.663557512232888 GO:0015132 prostaglandin transmembrane transporter activity 1/420 12/18639 0.0833333333333333 3.69821428571429 0.239345105354528 0.663557512232888 GO:0015166 polyol transmembrane transporter activity 1/420 12/18639 0.0833333333333333 3.69821428571429 0.239345105354528 0.663557512232888 GO:0031543 peptidyl-proline dioxygenase activity 1/420 12/18639 0.0833333333333333 3.69821428571429 0.239345105354528 0.663557512232888 GO:0035259 nuclear glucocorticoid receptor binding 1/420 12/18639 0.0833333333333333 3.69821428571429 0.239345105354528 0.663557512232888 GO:0035497 cAMP response element binding 1/420 12/18639 0.0833333333333333 3.69821428571429 0.239345105354528 0.663557512232888 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/420 12/18639 0.0833333333333333 3.69821428571429 0.239345105354528 0.663557512232888 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/420 12/18639 0.0833333333333333 3.69821428571429 0.239345105354528 0.663557512232888 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/420 12/18639 0.0833333333333333 3.69821428571429 0.239345105354528 0.663557512232888 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/420 12/18639 0.0833333333333333 3.69821428571429 0.239345105354528 0.663557512232888 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/420 12/18639 0.0833333333333333 3.69821428571429 0.239345105354528 0.663557512232888 GO:1990247 N6-methyladenosine-containing RNA reader activity 1/420 12/18639 0.0833333333333333 3.69821428571429 0.239345105354528 0.663557512232888 GO:1990459 transferrin receptor binding 1/420 12/18639 0.0833333333333333 3.69821428571429 0.239345105354528 0.663557512232888 GO:0004402 histone acetyltransferase activity 2/420 42/18639 0.0476190476190476 2.11326530612245 0.244258943448002 0.671044862856222 GO:0008307 structural constituent of muscle 2/420 42/18639 0.0476190476190476 2.11326530612245 0.244258943448002 0.671044862856222 GO:0019842 vitamin binding 5/420 150/18639 0.0333333333333333 1.47928571428571 0.250299007545303 0.671044862856222 GO:0048156 tau protein binding 2/420 43/18639 0.0465116279069767 2.0641196013289 0.252644683525915 0.671044862856222 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/420 13/18639 0.0769230769230769 3.41373626373626 0.256496286744505 0.671044862856222 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/420 13/18639 0.0769230769230769 3.41373626373626 0.256496286744505 0.671044862856222 GO:0005172 vascular endothelial growth factor receptor binding 1/420 13/18639 0.0769230769230769 3.41373626373626 0.256496286744505 0.671044862856222 GO:0008035 high-density lipoprotein particle binding 1/420 13/18639 0.0769230769230769 3.41373626373626 0.256496286744505 0.671044862856222 GO:0017154 semaphorin receptor activity 1/420 13/18639 0.0769230769230769 3.41373626373626 0.256496286744505 0.671044862856222 GO:0031432 titin binding 1/420 13/18639 0.0769230769230769 3.41373626373626 0.256496286744505 0.671044862856222 GO:0035325 Toll-like receptor binding 1/420 13/18639 0.0769230769230769 3.41373626373626 0.256496286744505 0.671044862856222 GO:0070700 BMP receptor binding 1/420 13/18639 0.0769230769230769 3.41373626373626 0.256496286744505 0.671044862856222 GO:0071714 icosanoid transmembrane transporter activity 1/420 13/18639 0.0769230769230769 3.41373626373626 0.256496286744505 0.671044862856222 GO:0089720 caspase binding 1/420 13/18639 0.0769230769230769 3.41373626373626 0.256496286744505 0.671044862856222 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/420 13/18639 0.0769230769230769 3.41373626373626 0.256496286744505 0.671044862856222 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/420 13/18639 0.0769230769230769 3.41373626373626 0.256496286744505 0.671044862856222 GO:0005085 guanyl-nucleotide exchange factor activity 7/420 230/18639 0.0304347826086957 1.35065217391304 0.262766221814901 0.67967366986849 GO:0016835 carbon-oxygen lyase activity 3/420 79/18639 0.0379746835443038 1.68526220614828 0.263240687198802 0.67967366986849 GO:0015294 solute:monoatomic cation symporter activity 4/420 116/18639 0.0344827586206897 1.53029556650246 0.26576267429491 0.67967366986849 GO:0005506 iron ion binding 5/420 154/18639 0.0324675324675325 1.44086270871985 0.267342718322589 0.67967366986849 GO:0008191 metalloendopeptidase inhibitor activity 1/420 14/18639 0.0714285714285714 3.16989795918367 0.273261644822852 0.67967366986849 GO:0008195 phosphatidate phosphatase activity 1/420 14/18639 0.0714285714285714 3.16989795918367 0.273261644822852 0.67967366986849 GO:0019992 diacylglycerol binding 1/420 14/18639 0.0714285714285714 3.16989795918367 0.273261644822852 0.67967366986849 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/420 14/18639 0.0714285714285714 3.16989795918367 0.273261644822852 0.67967366986849 GO:0032036 myosin heavy chain binding 1/420 14/18639 0.0714285714285714 3.16989795918367 0.273261644822852 0.67967366986849 GO:0034236 protein kinase A catalytic subunit binding 1/420 14/18639 0.0714285714285714 3.16989795918367 0.273261644822852 0.67967366986849 GO:0042813 Wnt receptor activity 1/420 14/18639 0.0714285714285714 3.16989795918367 0.273261644822852 0.67967366986849 GO:0070742 C2H2 zinc finger domain binding 1/420 14/18639 0.0714285714285714 3.16989795918367 0.273261644822852 0.67967366986849 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/420 14/18639 0.0714285714285714 3.16989795918367 0.273261644822852 0.67967366986849 GO:0001618 virus receptor activity 3/420 81/18639 0.037037037037037 1.64365079365079 0.27546974273931 0.67967366986849 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 2/420 46/18639 0.0434782608695652 1.92950310559006 0.277823983600452 0.67967366986849 GO:0140272 exogenous protein binding 3/420 82/18639 0.0365853658536585 1.623606271777 0.281606140813376 0.67967366986849 GO:0005504 fatty acid binding 2/420 47/18639 0.0425531914893617 1.88844984802432 0.286209946989024 0.67967366986849 GO:0061733 protein-lysine-acetyltransferase activity 2/420 47/18639 0.0425531914893617 1.88844984802432 0.286209946989024 0.67967366986849 GO:0004089 carbonate dehydratase activity 1/420 15/18639 0.0666666666666667 2.95857142857143 0.289649838604028 0.67967366986849 GO:0005041 low-density lipoprotein particle receptor activity 1/420 15/18639 0.0666666666666667 2.95857142857143 0.289649838604028 0.67967366986849 GO:0008242 omega peptidase activity 1/420 15/18639 0.0666666666666667 2.95857142857143 0.289649838604028 0.67967366986849 GO:0015250 water channel activity 1/420 15/18639 0.0666666666666667 2.95857142857143 0.289649838604028 0.67967366986849 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 1/420 15/18639 0.0666666666666667 2.95857142857143 0.289649838604028 0.67967366986849 GO:0051371 muscle alpha-actinin binding 1/420 15/18639 0.0666666666666667 2.95857142857143 0.289649838604028 0.67967366986849 GO:0061578 K63-linked deubiquitinase activity 1/420 15/18639 0.0666666666666667 2.95857142857143 0.289649838604028 0.67967366986849 GO:0140161 monocarboxylate:sodium symporter activity 1/420 15/18639 0.0666666666666667 2.95857142857143 0.289649838604028 0.67967366986849 GO:0140776 protein-containing complex destabilizing activity 1/420 15/18639 0.0666666666666667 2.95857142857143 0.289649838604028 0.67967366986849 GO:0051117 ATPase binding 3/420 84/18639 0.0357142857142857 1.58494897959184 0.293913307318948 0.67967366986849 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2/420 48/18639 0.0416666666666667 1.84910714285714 0.294585575397834 0.67967366986849 GO:0005004 GPI-linked ephrin receptor activity 2/420 49/18639 0.0408163265306122 1.81137026239067 0.30294708429944 0.67967366986849 GO:0005008 hepatocyte growth factor receptor activity 2/420 49/18639 0.0408163265306122 1.81137026239067 0.30294708429944 0.67967366986849 GO:0005009 insulin receptor activity 2/420 49/18639 0.0408163265306122 1.81137026239067 0.30294708429944 0.67967366986849 GO:0005011 macrophage colony-stimulating factor receptor activity 2/420 49/18639 0.0408163265306122 1.81137026239067 0.30294708429944 0.67967366986849 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/420 49/18639 0.0408163265306122 1.81137026239067 0.30294708429944 0.67967366986849 GO:0005020 stem cell factor receptor activity 2/420 49/18639 0.0408163265306122 1.81137026239067 0.30294708429944 0.67967366986849 GO:0008288 boss receptor activity 2/420 49/18639 0.0408163265306122 1.81137026239067 0.30294708429944 0.67967366986849 GO:0016763 pentosyltransferase activity 2/420 49/18639 0.0408163265306122 1.81137026239067 0.30294708429944 0.67967366986849 GO:0035254 glutamate receptor binding 2/420 49/18639 0.0408163265306122 1.81137026239067 0.30294708429944 0.67967366986849 GO:0036332 placental growth factor receptor activity 2/420 49/18639 0.0408163265306122 1.81137026239067 0.30294708429944 0.67967366986849 GO:0038062 protein tyrosine kinase collagen receptor activity 2/420 49/18639 0.0408163265306122 1.81137026239067 0.30294708429944 0.67967366986849 GO:0060175 brain-derived neurotrophic factor receptor activity 2/420 49/18639 0.0408163265306122 1.81137026239067 0.30294708429944 0.67967366986849 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/420 16/18639 0.0625 2.77366071428571 0.305669333223139 0.67967366986849 GO:0008142 oxysterol binding 1/420 16/18639 0.0625 2.77366071428571 0.305669333223139 0.67967366986849 GO:0015378 sodium:chloride symporter activity 1/420 16/18639 0.0625 2.77366071428571 0.305669333223139 0.67967366986849 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/420 16/18639 0.0625 2.77366071428571 0.305669333223139 0.67967366986849 GO:0017070 U6 snRNA binding 1/420 16/18639 0.0625 2.77366071428571 0.305669333223139 0.67967366986849 GO:0022858 alanine transmembrane transporter activity 1/420 16/18639 0.0625 2.77366071428571 0.305669333223139 0.67967366986849 GO:0050660 flavin adenine dinucleotide binding 3/420 86/18639 0.0348837209302326 1.54808970099668 0.306254219284751 0.67967366986849 GO:0005006 epidermal growth factor receptor activity 2/420 50/18639 0.04 1.77514285714286 0.311290864163434 0.67967366986849 GO:0005007 fibroblast growth factor receptor activity 2/420 50/18639 0.04 1.77514285714286 0.311290864163434 0.67967366986849 GO:0005017 platelet-derived growth factor receptor activity 2/420 50/18639 0.04 1.77514285714286 0.311290864163434 0.67967366986849 GO:0005019 platelet-derived growth factor beta-receptor activity 2/420 50/18639 0.04 1.77514285714286 0.311290864163434 0.67967366986849 GO:0005010 insulin-like growth factor receptor activity 2/420 51/18639 0.0392156862745098 1.74033613445378 0.319613474523777 0.67967366986849 GO:0005021 vascular endothelial growth factor receptor activity 2/420 51/18639 0.0392156862745098 1.74033613445378 0.319613474523777 0.67967366986849 GO:0005030 neurotrophin receptor activity 2/420 51/18639 0.0392156862745098 1.74033613445378 0.319613474523777 0.67967366986849 GO:0005048 signal sequence binding 2/420 51/18639 0.0392156862745098 1.74033613445378 0.319613474523777 0.67967366986849 GO:0016830 carbon-carbon lyase activity 2/420 51/18639 0.0392156862745098 1.74033613445378 0.319613474523777 0.67967366986849 GO:0004550 nucleoside diphosphate kinase activity 1/420 17/18639 0.0588235294117647 2.61050420168067 0.32132840426681 0.67967366986849 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/420 17/18639 0.0588235294117647 2.61050420168067 0.32132840426681 0.67967366986849 GO:0016018 cyclosporin A binding 1/420 17/18639 0.0588235294117647 2.61050420168067 0.32132840426681 0.67967366986849 GO:0016805 dipeptidase activity 1/420 17/18639 0.0588235294117647 2.61050420168067 0.32132840426681 0.67967366986849 GO:0017110 nucleoside diphosphate phosphatase activity 1/420 17/18639 0.0588235294117647 2.61050420168067 0.32132840426681 0.67967366986849 GO:0030169 low-density lipoprotein particle binding 1/420 17/18639 0.0588235294117647 2.61050420168067 0.32132840426681 0.67967366986849 GO:0038191 neuropilin binding 1/420 17/18639 0.0588235294117647 2.61050420168067 0.32132840426681 0.67967366986849 GO:0051787 misfolded protein binding 1/420 17/18639 0.0588235294117647 2.61050420168067 0.32132840426681 0.67967366986849 GO:0003712 transcription coregulator activity 13/420 495/18639 0.0262626262626263 1.16549783549784 0.325867693552901 0.67967366986849 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 2/420 52/18639 0.0384615384615385 1.70686813186813 0.327911638223603 0.67967366986849 GO:0005003 ephrin receptor activity 2/420 53/18639 0.0377358490566038 1.67466307277628 0.336182235832549 0.67967366986849 GO:0005005 transmembrane-ephrin receptor activity 2/420 53/18639 0.0377358490566038 1.67466307277628 0.336182235832549 0.67967366986849 GO:0005544 calcium-dependent phospholipid binding 2/420 53/18639 0.0377358490566038 1.67466307277628 0.336182235832549 0.67967366986849 GO:0016251 RNA polymerase II general transcription initiation factor activity 2/420 53/18639 0.0377358490566038 1.67466307277628 0.336182235832549 0.67967366986849 GO:0017046 peptide hormone binding 2/420 53/18639 0.0377358490566038 1.67466307277628 0.336182235832549 0.67967366986849 GO:0034212 protein N-acetyltransferase activity 2/420 53/18639 0.0377358490566038 1.67466307277628 0.336182235832549 0.67967366986849 GO:0038064 collagen receptor activity 2/420 53/18639 0.0377358490566038 1.67466307277628 0.336182235832549 0.67967366986849 GO:0051018 protein kinase A binding 2/420 53/18639 0.0377358490566038 1.67466307277628 0.336182235832549 0.67967366986849 GO:0005372 water transmembrane transporter activity 1/420 18/18639 0.0555555555555556 2.46547619047619 0.336635142007543 0.67967366986849 GO:0008308 voltage-gated monoatomic anion channel activity 1/420 18/18639 0.0555555555555556 2.46547619047619 0.336635142007543 0.67967366986849 GO:0015172 acidic amino acid transmembrane transporter activity 1/420 18/18639 0.0555555555555556 2.46547619047619 0.336635142007543 0.67967366986849 GO:0015373 monoatomic anion:sodium symporter activity 1/420 18/18639 0.0555555555555556 2.46547619047619 0.336635142007543 0.67967366986849 GO:0017128 phospholipid scramblase activity 1/420 18/18639 0.0555555555555556 2.46547619047619 0.336635142007543 0.67967366986849 GO:0030228 lipoprotein particle receptor activity 1/420 18/18639 0.0555555555555556 2.46547619047619 0.336635142007543 0.67967366986849 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/420 18/18639 0.0555555555555556 2.46547619047619 0.336635142007543 0.67967366986849 GO:0070064 proline-rich region binding 1/420 18/18639 0.0555555555555556 2.46547619047619 0.336635142007543 0.67967366986849 GO:0070628 proteasome binding 1/420 18/18639 0.0555555555555556 2.46547619047619 0.336635142007543 0.67967366986849 GO:0052689 carboxylic ester hydrolase activity 3/420 92/18639 0.0326086956521739 1.44712732919255 0.343342349256924 0.68791873406507 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 2/420 54/18639 0.037037037037037 1.64365079365079 0.344422300231771 0.68791873406507 GO:0050661 NADP binding 2/420 54/18639 0.037037037037037 1.64365079365079 0.344422300231771 0.68791873406507 GO:0051287 NAD binding 2/420 54/18639 0.037037037037037 1.64365079365079 0.344422300231771 0.68791873406507 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/420 19/18639 0.0526315789473684 2.33571428571429 0.351597455543703 0.691102935103098 GO:0015245 fatty acid transmembrane transporter activity 1/420 19/18639 0.0526315789473684 2.33571428571429 0.351597455543703 0.691102935103098 GO:0042577 lipid phosphatase activity 1/420 19/18639 0.0526315789473684 2.33571428571429 0.351597455543703 0.691102935103098 GO:0043395 heparan sulfate proteoglycan binding 1/420 19/18639 0.0526315789473684 2.33571428571429 0.351597455543703 0.691102935103098 GO:0070003 threonine-type peptidase activity 1/420 19/18639 0.0526315789473684 2.33571428571429 0.351597455543703 0.691102935103098 GO:0097001 ceramide binding 1/420 19/18639 0.0526315789473684 2.33571428571429 0.351597455543703 0.691102935103098 GO:0003823 antigen binding 5/420 174/18639 0.028735632183908 1.27524630541872 0.355414693778691 0.691386974157751 GO:0042562 hormone binding 3/420 94/18639 0.0319148936170213 1.41633738601824 0.355684061823147 0.691386974157751 GO:0000339 RNA cap binding 1/420 20/18639 0.05 2.21892857142857 0.366223076847228 0.691386974157751 GO:0001972 retinoic acid binding 1/420 20/18639 0.05 2.21892857142857 0.366223076847228 0.691386974157751 GO:0016004 phospholipase activator activity 1/420 20/18639 0.05 2.21892857142857 0.366223076847228 0.691386974157751 GO:0016505 peptidase activator activity involved in apoptotic process 1/420 20/18639 0.05 2.21892857142857 0.366223076847228 0.691386974157751 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/420 20/18639 0.05 2.21892857142857 0.366223076847228 0.691386974157751 GO:0042288 MHC class I protein binding 1/420 20/18639 0.05 2.21892857142857 0.366223076847228 0.691386974157751 GO:0004601 peroxidase activity 2/420 57/18639 0.0350877192982456 1.55714285714286 0.368931798468436 0.691386974157751 GO:0016504 peptidase activator activity 2/420 57/18639 0.0350877192982456 1.55714285714286 0.368931798468436 0.691386974157751 GO:0001846 opsonin binding 1/420 21/18639 0.0476190476190476 2.11326530612245 0.380519564721129 0.691386974157751 GO:0005123 death receptor binding 1/420 21/18639 0.0476190476190476 2.11326530612245 0.380519564721129 0.691386974157751 GO:0010314 phosphatidylinositol-5-phosphate binding 1/420 21/18639 0.0476190476190476 2.11326530612245 0.380519564721129 0.691386974157751 GO:0015174 basic amino acid transmembrane transporter activity 1/420 21/18639 0.0476190476190476 2.11326530612245 0.380519564721129 0.691386974157751 GO:0035613 RNA stem-loop binding 1/420 21/18639 0.0476190476190476 2.11326530612245 0.380519564721129 0.691386974157751 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/420 21/18639 0.0476190476190476 2.11326530612245 0.380519564721129 0.691386974157751 GO:0072542 protein phosphatase activator activity 1/420 21/18639 0.0476190476190476 2.11326530612245 0.380519564721129 0.691386974157751 GO:0030295 protein kinase activator activity 4/420 139/18639 0.0287769784172662 1.27708119218911 0.382766415722948 0.691386974157751 GO:0001786 phosphatidylserine binding 2/420 59/18639 0.0338983050847458 1.5043583535109 0.385070788128594 0.691386974157751 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 2/420 59/18639 0.0338983050847458 1.5043583535109 0.385070788128594 0.691386974157751 GO:0001098 basal transcription machinery binding 2/420 60/18639 0.0333333333333333 1.47928571428571 0.393073231062476 0.691386974157751 GO:0001099 basal RNA polymerase II transcription machinery binding 2/420 60/18639 0.0333333333333333 1.47928571428571 0.393073231062476 0.691386974157751 GO:0004714 transmembrane receptor protein tyrosine kinase activity 2/420 60/18639 0.0333333333333333 1.47928571428571 0.393073231062476 0.691386974157751 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 2/420 60/18639 0.0333333333333333 1.47928571428571 0.393073231062476 0.691386974157751 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 2/420 60/18639 0.0333333333333333 1.47928571428571 0.393073231062476 0.691386974157751 GO:0008093 cytoskeletal anchor activity 1/420 22/18639 0.0454545454545455 2.01720779220779 0.394494308668767 0.691386974157751 GO:0015377 chloride:monoatomic cation symporter activity 1/420 22/18639 0.0454545454545455 2.01720779220779 0.394494308668767 0.691386974157751 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 1/420 22/18639 0.0454545454545455 2.01720779220779 0.394494308668767 0.691386974157751 GO:0032931 histone H3K56 acetyltransferase activity 1/420 22/18639 0.0454545454545455 2.01720779220779 0.394494308668767 0.691386974157751 GO:0043992 histone H3K9 acetyltransferase activity 1/420 22/18639 0.0454545454545455 2.01720779220779 0.394494308668767 0.691386974157751 GO:0043993 histone H3K18 acetyltransferase activity 1/420 22/18639 0.0454545454545455 2.01720779220779 0.394494308668767 0.691386974157751 GO:0043994 histone H3K23 acetyltransferase activity 1/420 22/18639 0.0454545454545455 2.01720779220779 0.394494308668767 0.691386974157751 GO:0043999 histone H2AK5 acetyltransferase activity 1/420 22/18639 0.0454545454545455 2.01720779220779 0.394494308668767 0.691386974157751 GO:0044012 histone H2AK9 acetyltransferase activity 1/420 22/18639 0.0454545454545455 2.01720779220779 0.394494308668767 0.691386974157751 GO:0044014 histone H2BK5 acetyltransferase activity 1/420 22/18639 0.0454545454545455 2.01720779220779 0.394494308668767 0.691386974157751 GO:0044015 histone H2BK12 acetyltransferase activity 1/420 22/18639 0.0454545454545455 2.01720779220779 0.394494308668767 0.691386974157751 GO:0044016 histone H3K4 acetyltransferase activity 1/420 22/18639 0.0454545454545455 2.01720779220779 0.394494308668767 0.691386974157751 GO:0044017 histone H3K27 acetyltransferase activity 1/420 22/18639 0.0454545454545455 2.01720779220779 0.394494308668767 0.691386974157751 GO:0044018 histone H3K36 acetyltransferase activity 1/420 22/18639 0.0454545454545455 2.01720779220779 0.394494308668767 0.691386974157751 GO:0046972 histone H4K16 acetyltransferase activity 1/420 22/18639 0.0454545454545455 2.01720779220779 0.394494308668767 0.691386974157751 GO:0140517 protein-RNA adaptor activity 1/420 22/18639 0.0454545454545455 2.01720779220779 0.394494308668767 0.691386974157751 GO:0140784 metal ion sensor activity 1/420 22/18639 0.0454545454545455 2.01720779220779 0.394494308668767 0.691386974157751 GO:0140908 histone H3K122 acetyltransferase activity 1/420 22/18639 0.0454545454545455 2.01720779220779 0.394494308668767 0.691386974157751 GO:0020037 heme binding 4/420 142/18639 0.028169014084507 1.25010060362173 0.398075403808885 0.691386974157751 GO:0008237 metallopeptidase activity 5/420 184/18639 0.0271739130434783 1.20593944099379 0.400127951097209 0.691386974157751 GO:0015026 coreceptor activity 2/420 61/18639 0.0327868852459016 1.45503512880562 0.401028213922963 0.691386974157751 GO:0008514 organic anion transmembrane transporter activity 7/420 269/18639 0.0260223048327138 1.15483271375465 0.403721652109768 0.691386974157751 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/420 23/18639 0.0434782608695652 1.92950310559006 0.408154532676884 0.691386974157751 GO:0005212 structural constituent of eye lens 1/420 23/18639 0.0434782608695652 1.92950310559006 0.408154532676884 0.691386974157751 GO:0031681 G-protein beta-subunit binding 1/420 23/18639 0.0434782608695652 1.92950310559006 0.408154532676884 0.691386974157751 GO:0044013 histone H2B acetyltransferase activity 1/420 23/18639 0.0434782608695652 1.92950310559006 0.408154532676884 0.691386974157751 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/420 23/18639 0.0434782608695652 1.92950310559006 0.408154532676884 0.691386974157751 GO:0015179 L-amino acid transmembrane transporter activity 2/420 62/18639 0.032258064516129 1.4315668202765 0.408933811774841 0.691386974157751 GO:0031406 carboxylic acid binding 5/420 187/18639 0.0267379679144385 1.18659281894576 0.413500900371199 0.691386974157751 GO:0003779 actin binding 11/420 443/18639 0.0248306997742664 1.10195098355369 0.41464695628449 0.691386974157751 GO:0005507 copper ion binding 2/420 63/18639 0.0317460317460317 1.40884353741497 0.416788210071273 0.691386974157751 GO:0046943 carboxylic acid transmembrane transporter activity 5/420 188/18639 0.0265957446808511 1.1802811550152 0.417949235774909 0.691386974157751 GO:0015293 symporter activity 4/420 146/18639 0.0273972602739726 1.21585127201566 0.418384605725697 0.691386974157751 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/420 24/18639 0.0416666666666667 1.84910714285714 0.421507298914299 0.691386974157751 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/420 24/18639 0.0416666666666667 1.84910714285714 0.421507298914299 0.691386974157751 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/420 24/18639 0.0416666666666667 1.84910714285714 0.421507298914299 0.691386974157751 GO:0015295 solute:proton symporter activity 1/420 24/18639 0.0416666666666667 1.84910714285714 0.421507298914299 0.691386974157751 GO:0019957 C-C chemokine binding 1/420 24/18639 0.0416666666666667 1.84910714285714 0.421507298914299 0.691386974157751 GO:0030215 semaphorin receptor binding 1/420 24/18639 0.0416666666666667 1.84910714285714 0.421507298914299 0.691386974157751 GO:0030552 cAMP binding 1/420 24/18639 0.0416666666666667 1.84910714285714 0.421507298914299 0.691386974157751 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/420 24/18639 0.0416666666666667 1.84910714285714 0.421507298914299 0.691386974157751 GO:0043998 histone H2A acetyltransferase activity 1/420 24/18639 0.0416666666666667 1.84910714285714 0.421507298914299 0.691386974157751 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/420 24/18639 0.0416666666666667 1.84910714285714 0.421507298914299 0.691386974157751 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/420 24/18639 0.0416666666666667 1.84910714285714 0.421507298914299 0.691386974157751 GO:0060229 lipase activator activity 1/420 24/18639 0.0416666666666667 1.84910714285714 0.421507298914299 0.691386974157751 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/420 24/18639 0.0416666666666667 1.84910714285714 0.421507298914299 0.691386974157751 GO:0005342 organic acid transmembrane transporter activity 5/420 189/18639 0.0264550264550265 1.17403628117914 0.422392047093068 0.691386974157751 GO:0043177 organic acid binding 5/420 189/18639 0.0264550264550265 1.17403628117914 0.422392047093068 0.691386974157751 GO:0004536 DNA nuclease activity 2/420 64/18639 0.03125 1.38683035714286 0.424589700677254 0.691386974157751 GO:0005126 cytokine receptor binding 7/420 275/18639 0.0254545454545455 1.12963636363636 0.425817774233788 0.691386974157751 GO:0038024 cargo receptor activity 2/420 65/18639 0.0307692307692308 1.36549450549451 0.432336678015543 0.691386974157751 GO:0120013 lipid transfer activity 2/420 65/18639 0.0307692307692308 1.36549450549451 0.432336678015543 0.691386974157751 GO:0005251 delayed rectifier potassium channel activity 1/420 25/18639 0.04 1.77514285714286 0.434559511348142 0.691386974157751 GO:0008139 nuclear localization sequence binding 1/420 25/18639 0.04 1.77514285714286 0.434559511348142 0.691386974157751 GO:0008483 transaminase activity 1/420 25/18639 0.04 1.77514285714286 0.434559511348142 0.691386974157751 GO:0015271 outward rectifier potassium channel activity 1/420 25/18639 0.04 1.77514285714286 0.434559511348142 0.691386974157751 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/420 25/18639 0.04 1.77514285714286 0.434559511348142 0.691386974157751 GO:0015662 P-type ion transporter activity 1/420 25/18639 0.04 1.77514285714286 0.434559511348142 0.691386974157751 GO:0017025 TBP-class protein binding 1/420 25/18639 0.04 1.77514285714286 0.434559511348142 0.691386974157751 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/420 25/18639 0.04 1.77514285714286 0.434559511348142 0.691386974157751 GO:0019707 protein-cysteine S-acyltransferase activity 1/420 25/18639 0.04 1.77514285714286 0.434559511348142 0.691386974157751 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/420 25/18639 0.04 1.77514285714286 0.434559511348142 0.691386974157751 GO:0120020 cholesterol transfer activity 1/420 25/18639 0.04 1.77514285714286 0.434559511348142 0.691386974157751 GO:0140358 P-type transmembrane transporter activity 1/420 25/18639 0.04 1.77514285714286 0.434559511348142 0.691386974157751 GO:0008235 metalloexopeptidase activity 2/420 66/18639 0.0303030303030303 1.34480519480519 0.440027635331556 0.698590882588346 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/420 26/18639 0.0384615384615385 1.70686813186813 0.447317919279473 0.703080386871672 GO:0005160 transforming growth factor beta receptor binding 1/420 26/18639 0.0384615384615385 1.70686813186813 0.447317919279473 0.703080386871672 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/420 26/18639 0.0384615384615385 1.70686813186813 0.447317919279473 0.703080386871672 GO:0030247 polysaccharide binding 1/420 26/18639 0.0384615384615385 1.70686813186813 0.447317919279473 0.703080386871672 GO:0016500 protein-hormone receptor activity 2/420 67/18639 0.0298507462686567 1.32473347547974 0.447661161073859 0.703080386871672 GO:0046906 tetrapyrrole binding 4/420 152/18639 0.0263157894736842 1.16785714285714 0.448533113562816 0.703080386871672 GO:0046982 protein heterodimerization activity 9/420 369/18639 0.024390243902439 1.08240418118467 0.452211678358372 0.704178348726607 GO:0140223 general transcription initiation factor activity 2/420 68/18639 0.0294117647058824 1.30525210084034 0.455235935386955 0.704178348726607 GO:1902936 phosphatidylinositol bisphosphate binding 3/420 111/18639 0.027027027027027 1.19942084942085 0.458330471065127 0.704178348726607 GO:0001671 ATPase activator activity 1/420 27/18639 0.037037037037037 1.64365079365079 0.459789120800056 0.704178348726607 GO:0004364 glutathione transferase activity 1/420 27/18639 0.037037037037037 1.64365079365079 0.459789120800056 0.704178348726607 GO:0005385 zinc ion transmembrane transporter activity 1/420 27/18639 0.037037037037037 1.64365079365079 0.459789120800056 0.704178348726607 GO:0008266 poly(U) RNA binding 1/420 27/18639 0.037037037037037 1.64365079365079 0.459789120800056 0.704178348726607 GO:0008320 protein transmembrane transporter activity 1/420 27/18639 0.037037037037037 1.64365079365079 0.459789120800056 0.704178348726607 GO:0008395 steroid hydroxylase activity 1/420 27/18639 0.037037037037037 1.64365079365079 0.459789120800056 0.704178348726607 GO:0015252 proton channel activity 1/420 27/18639 0.037037037037037 1.64365079365079 0.459789120800056 0.704178348726607 GO:0035255 ionotropic glutamate receptor binding 1/420 27/18639 0.037037037037037 1.64365079365079 0.459789120800056 0.704178348726607 GO:0008080 N-acetyltransferase activity 2/420 69/18639 0.0289855072463768 1.28633540372671 0.462750726713171 0.704178348726607 GO:0097110 scaffold protein binding 2/420 70/18639 0.0285714285714286 1.26795918367347 0.470204388500517 0.704178348726607 GO:0016829 lyase activity 5/420 200/18639 0.025 1.10946428571429 0.470758240694362 0.704178348726607 GO:0005242 inward rectifier potassium channel activity 1/420 28/18639 0.0357142857142857 1.58494897959184 0.471979566172073 0.704178348726607 GO:0016866 intramolecular transferase activity 1/420 28/18639 0.0357142857142857 1.58494897959184 0.471979566172073 0.704178348726607 GO:0019789 SUMO transferase activity 1/420 28/18639 0.0357142857142857 1.58494897959184 0.471979566172073 0.704178348726607 GO:0036408 histone H3K14 acetyltransferase activity 1/420 28/18639 0.0357142857142857 1.58494897959184 0.471979566172073 0.704178348726607 GO:0045499 chemorepellent activity 1/420 28/18639 0.0357142857142857 1.58494897959184 0.471979566172073 0.704178348726607 GO:0046625 sphingolipid binding 1/420 28/18639 0.0357142857142857 1.58494897959184 0.471979566172073 0.704178348726607 GO:0046966 nuclear thyroid hormone receptor binding 1/420 28/18639 0.0357142857142857 1.58494897959184 0.471979566172073 0.704178348726607 GO:0051019 mitogen-activated protein kinase binding 1/420 28/18639 0.0357142857142857 1.58494897959184 0.471979566172073 0.704178348726607 GO:0051393 alpha-actinin binding 1/420 28/18639 0.0357142857142857 1.58494897959184 0.471979566172073 0.704178348726607 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/420 28/18639 0.0357142857142857 1.58494897959184 0.471979566172073 0.704178348726607 GO:0101005 deubiquitinase activity 3/420 115/18639 0.0260869565217391 1.15770186335404 0.481536979908606 0.713361908574239 GO:0004181 metallocarboxypeptidase activity 1/420 29/18639 0.0344827586206897 1.53029556650246 0.483895561132458 0.713361908574239 GO:0004629 phospholipase C activity 1/420 29/18639 0.0344827586206897 1.53029556650246 0.483895561132458 0.713361908574239 GO:0010484 histone H3 acetyltransferase activity 1/420 29/18639 0.0344827586206897 1.53029556650246 0.483895561132458 0.713361908574239 GO:0016417 S-acyltransferase activity 1/420 29/18639 0.0344827586206897 1.53029556650246 0.483895561132458 0.713361908574239 GO:0051861 glycolipid binding 1/420 29/18639 0.0344827586206897 1.53029556650246 0.483895561132458 0.713361908574239 GO:0015079 potassium ion transmembrane transporter activity 4/420 160/18639 0.025 1.10946428571429 0.487922253839325 0.716320330159151 GO:0043539 protein serine/threonine kinase activator activity 2/420 73/18639 0.0273972602739726 1.21585127201566 0.49218833991878 0.716320330159151 GO:0001968 fibronectin binding 1/420 30/18639 0.0333333333333333 1.47928571428571 0.495543270123558 0.716320330159151 GO:0008187 poly-pyrimidine tract binding 1/420 30/18639 0.0333333333333333 1.47928571428571 0.495543270123558 0.716320330159151 GO:0031210 phosphatidylcholine binding 1/420 30/18639 0.0333333333333333 1.47928571428571 0.495543270123558 0.716320330159151 GO:0033612 receptor serine/threonine kinase binding 1/420 30/18639 0.0333333333333333 1.47928571428571 0.495543270123558 0.716320330159151 GO:0043995 histone H4K5 acetyltransferase activity 1/420 30/18639 0.0333333333333333 1.47928571428571 0.495543270123558 0.716320330159151 GO:0043996 histone H4K8 acetyltransferase activity 1/420 30/18639 0.0333333333333333 1.47928571428571 0.495543270123558 0.716320330159151 GO:0043997 histone H4K12 acetyltransferase activity 1/420 30/18639 0.0333333333333333 1.47928571428571 0.495543270123558 0.716320330159151 GO:0051721 protein phosphatase 2A binding 1/420 30/18639 0.0333333333333333 1.47928571428571 0.495543270123558 0.716320330159151 GO:0003725 double-stranded RNA binding 2/420 75/18639 0.0266666666666667 1.18342857142857 0.50652118189129 0.724692225598471 GO:0019003 GDP binding 2/420 75/18639 0.0266666666666667 1.18342857142857 0.50652118189129 0.724692225598471 GO:0044183 protein folding chaperone 2/420 75/18639 0.0266666666666667 1.18342857142857 0.50652118189129 0.724692225598471 GO:0047499 calcium-independent phospholipase A2 activity 1/420 31/18639 0.032258064516129 1.4315668202765 0.506928719451738 0.724692225598471 GO:0072349 modified amino acid transmembrane transporter activity 1/420 31/18639 0.032258064516129 1.4315668202765 0.506928719451738 0.724692225598471 GO:0015081 sodium ion transmembrane transporter activity 4/420 164/18639 0.024390243902439 1.08240418118467 0.50718702195317 0.724692225598471 GO:0003697 single-stranded DNA binding 3/420 121/18639 0.0247933884297521 1.10029515938607 0.51543379657735 0.734574323814949 GO:0015106 bicarbonate transmembrane transporter activity 1/420 32/18639 0.03125 1.38683035714286 0.518057800375549 0.734574323814949 GO:0022884 macromolecule transmembrane transporter activity 1/420 32/18639 0.03125 1.38683035714286 0.518057800375549 0.734574323814949 GO:0047498 calcium-dependent phospholipase A2 activity 1/420 32/18639 0.03125 1.38683035714286 0.518057800375549 0.734574323814949 GO:0003724 RNA helicase activity 2/420 77/18639 0.025974025974026 1.15269016697588 0.52058850660703 0.736756686493377 GO:0019956 chemokine binding 1/420 33/18639 0.0303030303030303 1.34480519480519 0.528936272125013 0.745729886506422 GO:0140416 transcription regulator inhibitor activity 1/420 33/18639 0.0303030303030303 1.34480519480519 0.528936272125013 0.745729886506422 GO:0005267 potassium channel activity 3/420 124/18639 0.0241935483870968 1.07367511520737 0.5319328590371 0.747025759443247 GO:0008186 ATP-dependent activity, acting on RNA 2/420 79/18639 0.0253164556962025 1.12350813743219 0.534385474349049 0.747025759443247 GO:0015370 solute:sodium symporter activity 2/420 79/18639 0.0253164556962025 1.12350813743219 0.534385474349049 0.747025759443247 GO:0033293 monocarboxylic acid binding 2/420 79/18639 0.0253164556962025 1.12350813743219 0.534385474349049 0.747025759443247 GO:0051427 hormone receptor binding 1/420 34/18639 0.0294117647058824 1.30525210084034 0.539569764853568 0.747025759443247 GO:0090482 vitamin transmembrane transporter activity 1/420 34/18639 0.0294117647058824 1.30525210084034 0.539569764853568 0.747025759443247 GO:0015101 organic cation transmembrane transporter activity 2/420 81/18639 0.0246913580246914 1.0957671957672 0.547908200774073 0.747025759443247 GO:0033192 calmodulin-dependent protein phosphatase activity 2/420 81/18639 0.0246913580246914 1.0957671957672 0.547908200774073 0.747025759443247 GO:0140791 histone H2AXS140 phosphatase activity 2/420 81/18639 0.0246913580246914 1.0957671957672 0.547908200774073 0.747025759443247 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 2/420 81/18639 0.0246913580246914 1.0957671957672 0.547908200774073 0.747025759443247 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 2/420 81/18639 0.0246913580246914 1.0957671957672 0.547908200774073 0.747025759443247 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 2/420 81/18639 0.0246913580246914 1.0957671957672 0.547908200774073 0.747025759443247 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 2/420 81/18639 0.0246913580246914 1.0957671957672 0.547908200774073 0.747025759443247 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 2/420 81/18639 0.0246913580246914 1.0957671957672 0.547908200774073 0.747025759443247 GO:1990439 MAP kinase serine/threonine phosphatase activity 2/420 81/18639 0.0246913580246914 1.0957671957672 0.547908200774073 0.747025759443247 GO:0019783 ubiquitin-like protein peptidase activity 3/420 127/18639 0.0236220472440945 1.04831271091114 0.54811246928328 0.747025759443247 GO:0004623 phospholipase A2 activity 1/420 35/18639 0.0285714285714286 1.26795918367347 0.549963782524167 0.747025759443247 GO:0005154 epidermal growth factor receptor binding 1/420 35/18639 0.0285714285714286 1.26795918367347 0.549963782524167 0.747025759443247 GO:0010485 histone H4 acetyltransferase activity 1/420 35/18639 0.0285714285714286 1.26795918367347 0.549963782524167 0.747025759443247 GO:0043015 gamma-tubulin binding 1/420 35/18639 0.0285714285714286 1.26795918367347 0.549963782524167 0.747025759443247 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 2/420 82/18639 0.024390243902439 1.08240418118467 0.554565752273091 0.750532520835895 GO:0033549 MAP kinase phosphatase activity 2/420 82/18639 0.024390243902439 1.08240418118467 0.554565752273091 0.750532520835895 GO:0000993 RNA polymerase II complex binding 1/420 36/18639 0.0277777777777778 1.2327380952381 0.560123705730996 0.75259419771983 GO:0016409 palmitoyltransferase activity 1/420 36/18639 0.0277777777777778 1.2327380952381 0.560123705730996 0.75259419771983 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/420 36/18639 0.0277777777777778 1.2327380952381 0.560123705730996 0.75259419771983 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 2/420 83/18639 0.0240963855421687 1.06936316695353 0.561153681745338 0.75259419771983 GO:0030165 PDZ domain binding 2/420 83/18639 0.0240963855421687 1.06936316695353 0.561153681745338 0.75259419771983 GO:0016298 lipase activity 3/420 130/18639 0.0230769230769231 1.02412087912088 0.563960212210021 0.753648954239279 GO:0005543 phospholipid binding 11/420 497/18639 0.0221327967806841 0.982221902845645 0.567141659531307 0.753648954239279 GO:0017018 myosin phosphatase activity 2/420 84/18639 0.0238095238095238 1.05663265306122 0.567671739658176 0.753648954239279 GO:0019213 deacetylase activity 1/420 37/18639 0.027027027027027 1.19942084942085 0.570054794458243 0.753648954239279 GO:0022829 wide pore channel activity 1/420 37/18639 0.027027027027027 1.19942084942085 0.570054794458243 0.753648954239279 GO:0030551 cyclic nucleotide binding 1/420 37/18639 0.027027027027027 1.19942084942085 0.570054794458243 0.753648954239279 GO:0042805 actinin binding 1/420 37/18639 0.027027027027027 1.19942084942085 0.570054794458243 0.753648954239279 GO:0043394 proteoglycan binding 1/420 37/18639 0.027027027027027 1.19942084942085 0.570054794458243 0.753648954239279 GO:0000146 microfilament motor activity 1/420 38/18639 0.0263157894736842 1.16785714285714 0.579762190777324 0.762031135088247 GO:0042887 amide transmembrane transporter activity 1/420 38/18639 0.0263157894736842 1.16785714285714 0.579762190777324 0.762031135088247 GO:0043531 ADP binding 1/420 38/18639 0.0263157894736842 1.16785714285714 0.579762190777324 0.762031135088247 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 2/420 86/18639 0.0232558139534884 1.03205980066445 0.580497473028194 0.762031135088247 GO:0008081 phosphoric diester hydrolase activity 2/420 87/18639 0.0229885057471264 1.02019704433498 0.586804873964319 0.768952418616383 GO:0004197 cysteine-type endopeptidase activity 2/420 88/18639 0.0227272727272727 1.0086038961039 0.59304185057443 0.773399555134671 GO:0000287 magnesium ion binding 5/420 230/18639 0.0217391304347826 0.964751552795031 0.594462009411687 0.773399555134671 GO:0016779 nucleotidyltransferase activity 3/420 136/18639 0.0220588235294118 0.978939075630252 0.594619635217643 0.773399555134671 GO:0015144 carbohydrate transmembrane transporter activity 1/420 40/18639 0.025 1.10946428571429 0.598525900676226 0.773399555134671 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/420 40/18639 0.025 1.10946428571429 0.598525900676226 0.773399555134671 GO:0050997 quaternary ammonium group binding 1/420 40/18639 0.025 1.10946428571429 0.598525900676226 0.773399555134671 GO:0061791 GTPase motor activity 1/420 40/18639 0.025 1.10946428571429 0.598525900676226 0.773399555134671 GO:1990606 membrane scission GTPase motor activity 1/420 40/18639 0.025 1.10946428571429 0.598525900676226 0.773399555134671 GO:1901981 phosphatidylinositol phosphate binding 4/420 185/18639 0.0216216216216216 0.95953667953668 0.602341499869695 0.776978705561083 GO:0004812 aminoacyl-tRNA ligase activity 1/420 41/18639 0.024390243902439 1.08240418118467 0.607591932275558 0.777006550225025 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/420 41/18639 0.024390243902439 1.08240418118467 0.607591932275558 0.777006550225025 GO:0016875 ligase activity, forming carbon-oxygen bonds 1/420 41/18639 0.024390243902439 1.08240418118467 0.607591932275558 0.777006550225025 GO:0042169 SH2 domain binding 1/420 41/18639 0.024390243902439 1.08240418118467 0.607591932275558 0.777006550225025 GO:0140318 protein transporter activity 1/420 41/18639 0.024390243902439 1.08240418118467 0.607591932275558 0.777006550225025 GO:0070851 growth factor receptor binding 3/420 139/18639 0.0215827338129496 0.957810894141829 0.60941534444138 0.777999314295439 GO:0140597 protein carrier chaperone 4/420 188/18639 0.0212765957446809 0.944224924012158 0.615002869504123 0.780281274924552 GO:0004520 DNA endonuclease activity 1/420 42/18639 0.0238095238095238 1.05663265306122 0.616453712490864 0.780281274924552 GO:0031492 nucleosomal DNA binding 1/420 42/18639 0.0238095238095238 1.05663265306122 0.616453712490864 0.780281274924552 GO:0043175 RNA polymerase core enzyme binding 1/420 42/18639 0.0238095238095238 1.05663265306122 0.616453712490864 0.780281274924552 GO:0051879 Hsp90 protein binding 1/420 42/18639 0.0238095238095238 1.05663265306122 0.616453712490864 0.780281274924552 GO:0008200 ion channel inhibitor activity 1/420 43/18639 0.0232558139534884 1.03205980066445 0.625115832228125 0.789899767594382 GO:0016410 N-acyltransferase activity 2/420 94/18639 0.0212765957446809 0.944224924012158 0.628985293822536 0.791179840551935 GO:0015291 secondary active transmembrane transporter activity 6/420 287/18639 0.0209059233449477 0.927775012444002 0.63026845721355 0.791179840551935 GO:0019903 protein phosphatase binding 3/420 144/18639 0.0208333333333333 0.924553571428571 0.633263762566773 0.791179840551935 GO:0001223 transcription coactivator binding 1/420 44/18639 0.0227272727272727 1.0086038961039 0.633582779446032 0.791179840551935 GO:0016248 channel inhibitor activity 1/420 44/18639 0.0227272727272727 1.0086038961039 0.633582779446032 0.791179840551935 GO:0019205 nucleobase-containing compound kinase activity 1/420 44/18639 0.0227272727272727 1.0086038961039 0.633582779446032 0.791179840551935 GO:0030020 extracellular matrix structural constituent conferring tensile strength 1/420 44/18639 0.0227272727272727 1.0086038961039 0.633582779446032 0.791179840551935 GO:0004896 cytokine receptor activity 2/420 96/18639 0.0208333333333333 0.924553571428571 0.640405474790153 0.794835322506829 GO:0016407 acetyltransferase activity 2/420 96/18639 0.0208333333333333 0.924553571428571 0.640405474790153 0.794835322506829 GO:0046915 transition metal ion transmembrane transporter activity 1/420 45/18639 0.0222222222222222 0.986190476190476 0.641858941459081 0.794835322506829 GO:0140303 intramembrane lipid transporter activity 1/420 45/18639 0.0222222222222222 0.986190476190476 0.641858941459081 0.794835322506829 GO:0141110 transporter inhibitor activity 1/420 45/18639 0.0222222222222222 0.986190476190476 0.641858941459081 0.794835322506829 GO:0004180 carboxypeptidase activity 1/420 46/18639 0.0217391304347826 0.964751552795031 0.649948607189273 0.801489752161753 GO:0005249 voltage-gated potassium channel activity 2/420 98/18639 0.0204081632653061 0.905685131195335 0.651547523964602 0.801489752161753 GO:0008170 N-methyltransferase activity 2/420 98/18639 0.0204081632653061 0.905685131195335 0.651547523964602 0.801489752161753 GO:0042626 ATPase-coupled transmembrane transporter activity 2/420 98/18639 0.0204081632653061 0.905685131195335 0.651547523964602 0.801489752161753 GO:0008509 monoatomic anion transmembrane transporter activity 3/420 149/18639 0.0201342281879195 0.89352828379674 0.656084006593479 0.805736226279264 GO:0043495 protein-membrane adaptor activity 1/420 47/18639 0.0212765957446809 0.944224924012158 0.65785596936754 0.806579183564492 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/420 48/18639 0.0208333333333333 0.924553571428571 0.665585126686044 0.812035712853416 GO:0032266 phosphatidylinositol-3-phosphate binding 1/420 48/18639 0.0208333333333333 0.924553571428571 0.665585126686044 0.812035712853416 GO:0038187 pattern recognition receptor activity 1/420 48/18639 0.0208333333333333 0.924553571428571 0.665585126686044 0.812035712853416 GO:0030695 GTPase regulator activity 10/420 489/18639 0.0204498977505112 0.907537248028046 0.666924478377507 0.812335881040144 GO:0060589 nucleoside-triphosphatase regulator activity 10/420 490/18639 0.0204081632653061 0.905685131195335 0.669400212555386 0.814016952420052 GO:0008238 exopeptidase activity 2/420 102/18639 0.0196078431372549 0.870168067226891 0.673005794947909 0.814565283103431 GO:0001222 transcription corepressor binding 1/420 49/18639 0.0204081632653061 0.905685131195335 0.673140085902431 0.814565283103431 GO:0060590 ATPase regulator activity 1/420 49/18639 0.0204081632653061 0.905685131195335 0.673140085902431 0.814565283103431 GO:0004722 protein serine/threonine phosphatase activity 2/420 103/18639 0.0194174757281553 0.861719833564494 0.67820017093065 0.818023907469924 GO:0005253 monoatomic anion channel activity 2/420 103/18639 0.0194174757281553 0.861719833564494 0.67820017093065 0.818023907469924 GO:0032813 tumor necrosis factor receptor superfamily binding 1/420 50/18639 0.02 0.887571428571429 0.680524763897105 0.819497406119204 GO:0005272 sodium channel activity 1/420 51/18639 0.0196078431372549 0.870168067226891 0.687742989684571 0.825513798603613 GO:0030544 Hsp70 protein binding 1/420 51/18639 0.0196078431372549 0.870168067226891 0.687742989684571 0.825513798603613 GO:0005516 calmodulin binding 4/420 207/18639 0.0193236714975845 0.857556935817805 0.689177949257739 0.825901961771775 GO:0051015 actin filament binding 4/420 209/18639 0.0191387559808612 0.849350649350649 0.69636588888973 0.833172069959855 GO:0005246 calcium channel regulator activity 1/420 53/18639 0.0188679245283019 0.83733153638814 0.701694973121179 0.838198336059544 GO:0004843 cysteine-type deubiquitinase activity 2/420 108/18639 0.0185185185185185 0.821825396825397 0.703169698451095 0.838611694942477 GO:0005178 integrin binding 3/420 161/18639 0.0186335403726708 0.826929902395741 0.706627705790309 0.839502270244523 GO:0004620 phospholipase activity 2/420 109/18639 0.018348623853211 0.814285714285714 0.707966085956163 0.839502270244523 GO:0017069 snRNA binding 1/420 54/18639 0.0185185185185185 0.821825396825397 0.708435966949282 0.839502270244523 GO:0140463 chromatin-protein adaptor activity 1/420 54/18639 0.0185185185185185 0.821825396825397 0.708435966949282 0.839502270244523 GO:0004222 metalloendopeptidase activity 2/420 110/18639 0.0181818181818182 0.806883116883117 0.712697685656151 0.843207612169618 GO:0008374 O-acyltransferase activity 1/420 55/18639 0.0181818181818182 0.806883116883117 0.715024984645343 0.844616158333052 GO:0030170 pyridoxal phosphate binding 1/420 56/18639 0.0178571428571429 0.792474489795918 0.721465444527444 0.850871151244271 GO:0070279 vitamin B6 binding 1/420 57/18639 0.0175438596491228 0.778571428571429 0.727760688207069 0.85693532700135 GO:0016874 ligase activity 3/420 167/18639 0.0179640718562874 0.797219846022241 0.729682112051911 0.857838305782548 GO:0008408 3'-5' exonuclease activity 1/420 58/18639 0.0172413793103448 0.765147783251231 0.73391398230636 0.859124039789373 GO:0017124 SH3 domain binding 2/420 115/18639 0.0173913043478261 0.771801242236025 0.735400927733568 0.859124039789373 GO:0035401 histone H3Y41 kinase activity 2/420 115/18639 0.0173913043478261 0.771801242236025 0.735400927733568 0.859124039789373 GO:0140801 histone H2AXY142 kinase activity 2/420 115/18639 0.0173913043478261 0.771801242236025 0.735400927733568 0.859124039789373 GO:0031593 polyubiquitin modification-dependent protein binding 1/420 59/18639 0.0169491525423729 0.752179176755448 0.739928520137011 0.861703590065516 GO:0036002 pre-mRNA binding 1/420 59/18639 0.0169491525423729 0.752179176755448 0.739928520137011 0.861703590065516 GO:0005244 voltage-gated monoatomic ion channel activity 3/420 173/18639 0.0173410404624277 0.769570602807597 0.751292533716746 0.87114575884476 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/420 61/18639 0.0163934426229508 0.72751756440281 0.751553743498643 0.87114575884476 GO:0016836 hydro-lyase activity 1/420 61/18639 0.0163934426229508 0.72751756440281 0.751553743498643 0.87114575884476 GO:0022832 voltage-gated channel activity 3/420 175/18639 0.0171428571428571 0.760775510204082 0.758181532206557 0.877450602422269 GO:0015108 chloride transmembrane transporter activity 2/420 121/18639 0.0165289256198347 0.733530106257379 0.760612811569255 0.877450602422269 GO:0004252 serine-type endopeptidase activity 3/420 176/18639 0.0170454545454545 0.756452922077922 0.761567950824594 0.877450602422269 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 4/420 229/18639 0.0174672489082969 0.775171553337492 0.761716875588645 0.877450602422269 GO:0008528 G protein-coupled peptide receptor activity 2/420 122/18639 0.0163934426229508 0.72751756440281 0.764606889557656 0.879416283190927 GO:0035091 phosphatidylinositol binding 5/420 284/18639 0.0176056338028169 0.781312877263582 0.770172755906771 0.884448775330341 GO:0160215 deacylase activity 1/420 65/18639 0.0153846153846154 0.682747252747253 0.773271859847589 0.886637333127714 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 3/420 181/18639 0.0165745856353591 0.735556432517758 0.777927870027225 0.890601552280783 GO:0042826 histone deacetylase binding 2/420 127/18639 0.015748031496063 0.698875140607424 0.783720337877418 0.895852632373726 GO:0001653 peptide receptor activity 2/420 128/18639 0.015625 0.693415178571429 0.78737570065741 0.896956867544291 GO:0005548 phospholipid transporter activity 1/420 68/18639 0.0147058823529412 0.652626050420168 0.788307987222641 0.896956867544291 GO:0030145 manganese ion binding 1/420 68/18639 0.0147058823529412 0.652626050420168 0.788307987222641 0.896956867544291 GO:0008234 cysteine-type peptidase activity 3/420 187/18639 0.0160427807486631 0.711955691367456 0.796331625272599 0.904700913727127 GO:0005179 hormone activity 2/420 132/18639 0.0151515151515152 0.672402597402597 0.801458947472258 0.908758279062475 GO:0140299 molecular sensor activity 1/420 71/18639 0.0140845070422535 0.625050301810865 0.802349166978443 0.908758279062475 GO:0019902 phosphatase binding 3/420 190/18639 0.0157894736842105 0.700714285714286 0.80504663006452 0.910425641001429 GO:0004175 endopeptidase activity 7/420 405/18639 0.0172839506172839 0.767037037037037 0.810541912916363 0.913283046855305 GO:0044325 transmembrane transporter binding 2/420 136/18639 0.0147058823529412 0.652626050420168 0.814709419013011 0.913283046855305 GO:0140789 histone phosphatase activity 2/420 136/18639 0.0147058823529412 0.652626050420168 0.814709419013011 0.913283046855305 GO:0003684 damaged DNA binding 1/420 74/18639 0.0135135135135135 0.599710424710425 0.815461088565048 0.913283046855305 GO:0031491 nucleosome binding 1/420 74/18639 0.0135135135135135 0.599710424710425 0.815461088565048 0.913283046855305 GO:0140104 molecular carrier activity 4/420 249/18639 0.0160642570281124 0.712908777969019 0.815616322224511 0.913283046855305 GO:0008236 serine-type peptidase activity 3/420 194/18639 0.0154639175257732 0.686266568483063 0.816177581577285 0.913283046855305 GO:0016922 nuclear receptor binding 2/420 137/18639 0.0145985401459854 0.647862356621481 0.817896348652 0.913830055711933 GO:0051536 iron-sulfur cluster binding 1/420 76/18639 0.0131578947368421 0.583928571428571 0.823716586735065 0.917887910119615 GO:0140101 catalytic activity, acting on a tRNA 2/420 139/18639 0.0143884892086331 0.638540596094553 0.824123508693227 0.917887910119615 GO:0017171 serine hydrolase activity 3/420 198/18639 0.0151515151515152 0.672402597402597 0.826765547999897 0.917887910119615 GO:0004713 protein tyrosine kinase activity 2/420 140/18639 0.0142857142857143 0.633979591836735 0.82716491333561 0.917887910119615 GO:0051540 metal cluster binding 1/420 77/18639 0.012987012987013 0.576345083487941 0.827705114105171 0.917887910119615 GO:0022843 voltage-gated monoatomic cation channel activity 2/420 143/18639 0.013986013986014 0.620679320679321 0.836007434947547 0.925713150769042 GO:0030971 receptor tyrosine kinase binding 1/420 81/18639 0.0123456790123457 0.547883597883598 0.842778942346305 0.931822550838251 GO:0005254 chloride channel activity 1/420 83/18639 0.0120481927710843 0.534681583476764 0.849814976806521 0.938205836206902 GO:0004527 exonuclease activity 1/420 84/18639 0.0119047619047619 0.528316326530612 0.853214292916742 0.939758922743817 GO:0000510 H3-H4 histone complex chaperone activity 2/420 151/18639 0.0132450331125828 0.587795648060549 0.857623110214267 0.939758922743817 GO:0140584 chromatin extrusion motor activity 2/420 151/18639 0.0132450331125828 0.587795648060549 0.857623110214267 0.939758922743817 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 2/420 151/18639 0.0132450331125828 0.587795648060549 0.857623110214267 0.939758922743817 GO:0140849 ATP-dependent H2AZ histone chaperone activity 2/420 151/18639 0.0132450331125828 0.587795648060549 0.857623110214267 0.939758922743817 GO:0015616 DNA translocase activity 2/420 152/18639 0.0131578947368421 0.583928571428571 0.860134365370108 0.939758922743817 GO:0140674 ATP-dependent histone chaperone activity 2/420 152/18639 0.0131578947368421 0.583928571428571 0.860134365370108 0.939758922743817 GO:0003774 cytoskeletal motor activity 2/420 153/18639 0.0130718954248366 0.580112044817927 0.862605094631606 0.939758922743817 GO:0061775 cohesin loader activity 2/420 153/18639 0.0130718954248366 0.580112044817927 0.862605094631606 0.939758922743817 GO:0004386 helicase activity 2/420 155/18639 0.0129032258064516 0.572626728110599 0.867427154478504 0.941531552361675 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/420 89/18639 0.0112359550561798 0.498635634028892 0.86909345708974 0.941531552361675 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/420 89/18639 0.0112359550561798 0.498635634028892 0.86909345708974 0.941531552361675 GO:0140375 immune receptor activity 2/420 156/18639 0.0128205128205128 0.568956043956044 0.869779564591905 0.941531552361675 GO:0140793 histone H2AXY142 phosphatase activity 1/420 90/18639 0.0111111111111111 0.493095238095238 0.87205737881601 0.941531552361675 GO:0008017 microtubule binding 4/420 276/18639 0.0144927536231884 0.643167701863354 0.872117487541715 0.941531552361675 GO:0016755 aminoacyltransferase activity 8/420 496/18639 0.0161290322580645 0.715783410138249 0.874079354322292 0.941531552361675 GO:0140658 ATP-dependent chromatin remodeler activity 2/420 158/18639 0.0126582278481013 0.561754068716094 0.87436981309496 0.941531552361675 GO:0003689 DNA clamp loader activity 2/420 160/18639 0.0125 0.554732142857143 0.878810806792499 0.943578655269981 GO:0099106 ion channel regulator activity 2/420 160/18639 0.0125 0.554732142857143 0.878810806792499 0.943578655269981 GO:0046873 metal ion transmembrane transporter activity 7/420 450/18639 0.0155555555555556 0.690333333333333 0.88421084301876 0.94800671913844 GO:0140713 histone chaperone activity 2/420 164/18639 0.0121951219512195 0.541202090592334 0.887261547270563 0.949906815017331 GO:0015103 inorganic anion transmembrane transporter activity 2/420 165/18639 0.0121212121212121 0.537922077922078 0.889287340570271 0.950705746825484 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 2/420 167/18639 0.0119760479041916 0.531479897348161 0.893238125027276 0.952448246715341 GO:0004725 protein tyrosine phosphatase activity 1/420 98/18639 0.0102040816326531 0.452842565597668 0.893481060512238 0.952448246715341 GO:0016247 channel regulator activity 2/420 168/18639 0.0119047619047619 0.528316326530612 0.895164088033648 0.952875239840975 GO:0043130 ubiquitin binding 1/420 100/18639 0.01 0.443785714285714 0.898252369559663 0.954138892756716 GO:0141108 transporter regulator activity 2/420 170/18639 0.0117647058823529 0.522100840336134 0.898919549030553 0.954138892756716 GO:0005125 cytokine activity 3/420 234/18639 0.0128205128205128 0.568956043956044 0.900614026442744 0.954573782663279 GO:0061630 ubiquitin protein ligase activity 5/420 353/18639 0.0141643059490085 0.628591663294213 0.902518092517816 0.955229263163444 GO:0045182 translation regulator activity 5/420 356/18639 0.0140449438202247 0.623294542536116 0.90634772556611 0.957918008670868 GO:0004721 phosphoprotein phosphatase activity 2/420 175/18639 0.0114285714285714 0.507183673469388 0.907767257956422 0.958055500939803 GO:0004497 monooxygenase activity 1/420 106/18639 0.00943396226415094 0.41866576819407 0.91132449298358 0.960445529484823 GO:0042578 phosphoric ester hydrolase activity 5/420 363/18639 0.0137741046831956 0.611275088547816 0.914777559565578 0.962719159712782 GO:0019787 ubiquitin-like protein transferase activity 7/420 479/18639 0.0146137787056367 0.648538622129436 0.917688798135443 0.964416940614758 GO:0061659 ubiquitin-like protein ligase activity 5/420 372/18639 0.0134408602150538 0.596486175115207 0.924633001800525 0.97034226036411 GO:1990782 protein tyrosine kinase binding 1/420 117/18639 0.00854700854700855 0.379304029304029 0.931092727716442 0.975743154715538 GO:0032182 ubiquitin-like protein binding 1/420 120/18639 0.00833333333333333 0.369821428571429 0.935675048353154 0.9757560496204 GO:0015631 tubulin binding 5/420 385/18639 0.012987012987013 0.576345083487941 0.937086990884292 0.9757560496204 GO:0005216 monoatomic ion channel activity 6/420 448/18639 0.0133928571428571 0.594355867346939 0.940669108241315 0.9757560496204 GO:0004842 ubiquitin-protein transferase activity 6/420 449/18639 0.0133630289532294 0.593032134902959 0.941451835981624 0.9757560496204 GO:0016757 glycosyltransferase activity 3/420 267/18639 0.0112359550561798 0.498635634028892 0.942004786049118 0.9757560496204 GO:0004519 endonuclease activity 1/420 127/18639 0.0078740157480315 0.349437570303712 0.945219325426849 0.9757560496204 GO:0005096 GTPase activator activity 3/420 271/18639 0.011070110701107 0.49127569847127 0.945759156197509 0.9757560496204 GO:0003714 transcription corepressor activity 2/420 204/18639 0.00980392156862745 0.435084033613445 0.946334858585981 0.9757560496204 GO:0008168 methyltransferase activity 2/420 204/18639 0.00980392156862745 0.435084033613445 0.946334858585981 0.9757560496204 GO:0140097 catalytic activity, acting on DNA 4/420 336/18639 0.0119047619047619 0.528316326530612 0.946991068070632 0.9757560496204 GO:0016791 phosphatase activity 3/420 273/18639 0.010989010989011 0.487676609105181 0.947550634749362 0.9757560496204 GO:0035591 signaling adaptor activity 1/420 129/18639 0.00775193798449612 0.344019933554817 0.947676919356926 0.9757560496204 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/420 130/18639 0.00769230769230769 0.341373626373626 0.948864152953365 0.9757560496204 GO:0005261 monoatomic cation channel activity 4/420 341/18639 0.0117302052785924 0.520569752827817 0.950919684520694 0.9757560496204 GO:0004518 nuclease activity 2/420 209/18639 0.00956937799043062 0.424675324675325 0.951196645680185 0.9757560496204 GO:0008094 ATP-dependent activity, acting on DNA 2/420 210/18639 0.00952380952380952 0.42265306122449 0.952117275874549 0.9757560496204 GO:0099094 ligand-gated monoatomic cation channel activity 1/420 136/18639 0.00735294117647059 0.326313025210084 0.955443927629266 0.977527658776369 GO:0016741 transferase activity, transferring one-carbon groups 2/420 215/18639 0.00930232558139535 0.412823920265781 0.956477265047672 0.977527658776369 GO:0016887 ATP hydrolysis activity 5/420 417/18639 0.0119904076738609 0.532117163412127 0.960251393512213 0.980036793103811 GO:0001664 G protein-coupled receptor binding 3/420 297/18639 0.0101010101010101 0.448268398268398 0.965159888580297 0.983695195082525 GO:0004674 protein serine/threonine kinase activity 5/420 433/18639 0.0115473441108545 0.51245463543385 0.968632546515132 0.985882167206498 GO:0022836 gated channel activity 3/420 318/18639 0.00943396226415094 0.41866576819407 0.975847417226306 0.989911812628156 GO:0140098 catalytic activity, acting on RNA 4/420 387/18639 0.0103359173126615 0.458693244739756 0.976359429183421 0.989911812628156 GO:0042393 histone binding 2/420 247/18639 0.00809716599190283 0.359340659340659 0.976588638837737 0.989911812628156 GO:0140030 modification-dependent protein binding 1/420 173/18639 0.00578034682080925 0.256523534269199 0.980963299320293 0.992991459666182 GO:0015276 ligand-gated monoatomic ion channel activity 1/420 186/18639 0.00537634408602151 0.238594470046083 0.985885855784692 0.995903724845433 GO:0022834 ligand-gated channel activity 1/420 188/18639 0.00531914893617021 0.23605623100304 0.986521051798437 0.995903724845433 GO:0016758 hexosyltransferase activity 1/420 197/18639 0.0050761421319797 0.225271936185642 0.989044419325018 0.997096341327664 GO:0051020 GTPase binding 2/420 315/18639 0.00634920634920635 0.281768707482993 0.993988998289017 0.999482150963417 GO:0141003 histone H2AX kinase activity 2/420 354/18639 0.00564971751412429 0.250726392251816 0.997298576015051 0.999482150963417 GO:0140996 histone H3 kinase activity 2/420 357/18639 0.00560224089635854 0.248619447779112 0.997461052681851 0.999482150963417 GO:0035173 histone kinase activity 2/420 360/18639 0.00555555555555556 0.246547619047619 0.997613918671219 0.999482150963417 GO:0031267 small GTPase binding 1/420 283/18639 0.00353356890459364 0.156814740030288 0.99849619881316 0.999482150963417 GO:0030371 translation repressor activity 1/420 329/18639 0.00303951367781155 0.13488927485888 0.999482150963417 0.999482150963417