category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 70/149 238/9376 18.507698381366 RPS26/RPL21/RPL9/RPL23A/RPS13/RPL23/RPL30/RPL37A/RPS2/RPL39/RPS7/RPL7/RPS10/FOS/RPS20/RPS12/RPS27A/RPL10A/RPLP2/RPS3A/RPL26/RPL13A/RPS18/RPS15/RPL24/RPL27A/RPLP1/RPL28/RPL36/RPS11/RPL17/RPS15A/RPL38/RPS3/RPL18/RPS16/JUN/RPL35A/RPL13/RPL11/RPS23/RPL41/RPL27/RPL36A/RPS8/RPL14/RPL35/RPS24/RPL18A/RPS17/FAU/RPL31/RPS19/RPS25/RPL7A/RPL36AL/RPSA/RPL37/RPS6/RPS14/RPS4Y1/RPL5/RPL32/RPL8/UBA52/RPL15/RPL19/RPS29/RPL10/RPS5 34.7648588033191 Genetic Information Processing Translation hsa03010 Ribosome 68/149 222/9376 19.2746840800532 RPS26/RPL21/RPL9/RPL23A/RPS13/RPL23/RPL30/RPL37A/RPS2/RPL39/RPS7/RPL7/RPS10/RPS20/RPS12/RPS27A/RPL10A/RPLP2/RPS3A/RPL26/RPL13A/RPS18/RPS15/RPL24/RPL27A/RPLP1/RPL28/RPL36/RPS11/RPL17/RPS15A/RPL38/RPS3/RPL18/RPS16/RPL35A/RPL13/RPL11/RPS23/RPL41/RPL27/RPL36A/RPS8/RPL14/RPL35/RPS24/RPL18A/RPS17/FAU/RPL31/RPS19/RPS25/RPL7A/RPL36AL/RPSA/RPL37/RPS6/RPS14/RPS4Y1/RPL5/RPL32/RPL8/UBA52/RPL15/RPL19/RPS29/RPL10/RPS5 35.0162329807373 Human Diseases Endocrine and metabolic disease hsa04932 Non-alcoholic fatty liver disease 7/149 157/9376 2.80562561450006 FOS/NDUFA4L2/JUN/SOCS3/MT-CO3/COX6C/COX7C 2.89923979925804 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 8/149 196/9376 2.56841528557732 FOS/RPS27A/HLA-C/JUN/CCND1/GNG5/UBA52/ZFP36 2.81978680144626 Environmental Information Processing Signal transduction hsa04371 Apelin signaling pathway 6/149 140/9376 2.69683604985618 EGR1/KLF2/CCND1/RPS6/GNG5/SERPINE1 2.57045763334057 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 8/149 224/9376 2.24736337488015 EGR1/FOS/HLA-C/JUN/CCND1/CDKN2A/EGR2/ZFP36 2.40108482881194 Human Diseases Neurodegenerative disease hsa05012 Parkinson disease 9/149 268/9376 2.11319242712611 RPS27A/NDUFA4L2/HSPA5/DUSP1/UBA52/MT-CO3/SLC39A4/COX6C/COX7C 2.34949562888821 Cellular Processes Cell growth and death hsa04218 Cellular senescence 6/149 157/9376 2.40482195528577 ZFP36L1/HLA-C/ZFP36L2/CCND1/CDKN2A/SERPINE1 2.25568118381157 Organismal Systems Digestive system hsa04979 Cholesterol metabolism 3/149 52/9376 3.63035622096025 ANGPTL4/APOC1/APOE 2.41692747741781 Organismal Systems Circulatory system hsa04260 Cardiac muscle contraction 4/149 87/9376 2.89315744812158 ATP1B1/MT-CO3/COX6C/COX7C 2.25429315007008 Human Diseases Cancer: specific types hsa05210 Colorectal cancer 4/149 87/9376 2.89315744812158 FOS/JUN/CCND1/AREG 2.25429315007008 Organismal Systems Immune system hsa04657 IL-17 signaling pathway 4/149 94/9376 2.67770955304869 FOSB/FOS/HSP90AA1/JUN 2.07734406870589 Human Diseases Drug resistance: antineoplastic hsa01522 Endocrine resistance 4/149 99/9376 2.54247169683411 FOS/JUN/CCND1/CDKN2A 1.96055727847191 Organismal Systems Digestive system hsa04978 Mineral absorption 3/149 61/9376 3.09472989327759 ATP1B1/FTH1/SLC39A4 2.08569130408831 Organismal Systems Development and regeneration hsa04380 Osteoclast differentiation 5/149 142/9376 2.21571036960015 JUNB/FOSB/FOS/JUN/SOCS3 1.85493147402239 Human Diseases Cardiovascular disease hsa05418 Fluid shear stress and atherosclerosis 5/149 142/9376 2.21571036960015 FOS/HSP90AA1/JUN/KLF2/DUSP1 1.85493147402239 Human Diseases Endocrine and metabolic disease hsa04933 AGE-RAGE signaling pathway in diabetic complications 4/149 101/9376 2.49212572263938 EGR1/JUN/CCND1/SERPINE1 1.91583303261189 Cellular Processes Transport and catabolism hsa04137 Mitophagy - animal 4/149 105/9376 2.39718759987216 RPS27A/JUN/UBA52/CCZ1 1.82950918288348 Genetic Information Processing Folding, sorting and degradation hsa03060 Protein export 2/149 31/9376 4.05975319333189 HSPA5/SEC61B 2.16833361639124 Human Diseases Substance dependence hsa05031 Amphetamine addiction 3/149 69/9376 2.73592063028888 FOSB/FOS/JUN 1.83906917436582 Environmental Information Processing Signal transduction hsa04066 HIF-1 signaling pathway 4/149 110/9376 2.2882245271507 LDHA/ALDOA/RPS6/SERPINE1 1.72699177977224 Environmental Information Processing Signal transduction hsa04350 TGF-beta signaling pathway 4/149 110/9376 2.2882245271507 ID3/ID1/EMP3/ID2 1.72699177977224 Organismal Systems Endocrine system hsa04917 Prolactin signaling pathway 3/149 71/9376 2.65885244352018 FOS/CCND1/SOCS3 1.78290110674173 Environmental Information Processing Signal transduction hsa04390 Hippo signaling pathway 5/149 157/9376 2.00401829607147 CCND1/AREG/ID1/SERPINE1/ID2 1.6121225683651 Cellular Processes Cell growth and death hsa04115 p53 signaling pathway 3/149 75/9376 2.51704697986577 CCND1/CDKN2A/SERPINE1 1.67615181561348 Organismal Systems Endocrine system hsa04918 Thyroid hormone synthesis 3/149 75/9376 2.51704697986577 ATP1B1/GPX8/HSPA5 1.67615181561348 Environmental Information Processing Signal transduction hsa04668 TNF signaling pathway 4/149 119/9376 2.11516552929897 JUNB/FOS/JUN/SOCS3 1.55570123861433 Human Diseases Infectious disease: parasitic hsa05140 Leishmaniasis 3/149 78/9376 2.42023748064017 EEF1A1/FOS/JUN 1.6005233417215 Organismal Systems Endocrine system hsa04935 Growth hormone synthesis, secretion and action 4/149 122/9376 2.06315326218506 CSH1/JUNB/FOS/SOCS3 1.50196411280404 Human Diseases Cancer: specific types hsa05219 Bladder cancer 2/149 41/9376 3.06956948764119 CCND1/CDKN2A 1.6875758124119 Organismal Systems Immune system hsa04612 Antigen processing and presentation 3/149 82/9376 2.30217711573089 HSP90AA1/HLA-C/HSPA5 1.50495724857444 Genetic Information Processing Folding, sorting and degradation hsa04141 Protein processing in endoplasmic reticulum 5/149 174/9376 1.80822340507599 HSP90AA1/DNAJA1/HSPA5/SEC61B/PDIA6 1.36745626297771 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 6/149 227/9376 1.663246902995 FOS/NDUFA4L2/JUN/MT-CO3/COX6C/COX7C 1.28543422119067 Cellular Processes Cell motility hsa04820 Cytoskeleton in muscle cells 6/149 233/9376 1.6204165106432 VCAN/ATP1B1/TNNT3/NID2/NEBL/COL9A3 1.21861202561521 Human Diseases Infectious disease: viral hsa05162 Measles 4/149 136/9376 1.8507698381366 FOS/JUN/CCND1/EIF3H 1.26997176468149 Metabolism Energy metabolism hsa00190 Oxidative phosphorylation 4/149 138/9376 1.82394708685926 NDUFA4L2/MT-CO3/COX6C/COX7C 1.2390772948586 Organismal Systems Endocrine system hsa04915 Estrogen signaling pathway 4/149 139/9376 1.81082516537106 FOS/HSP90AA1/JUN/KRT19 1.22382031970865 Human Diseases Substance dependence hsa05030 Cocaine addiction 2/149 49/9376 2.56841528557732 FOSB/JUN 1.39873882544193 Human Diseases Infectious disease: bacterial hsa05110 Vibrio cholerae infection 2/149 51/9376 2.46769311751546 KDELR2/SEC61B 1.33550167667561 Cellular Processes Cellular community - eukaryotes hsa04550 Signaling pathways regulating pluripotency of stem cells 4/149 144/9376 1.74794929157345 ID3/KLF4/ID1/ID2 1.14935453937689 Metabolism Glycan biosynthesis and metabolism hsa00533 Glycosaminoglycan biosynthesis - keratan sulfate 1/149 14/9376 4.49472674976031 CHST2 1.66280543657675 Organismal Systems Endocrine system hsa04925 Aldosterone synthesis and secretion 3/149 98/9376 1.92631146418299 ATP1B1/NR4A1/KCNK3 1.17136273850801 Metabolism Amino acid metabolism hsa00270 Cysteine and methionine metabolism 2/149 54/9376 2.33059905543127 LDHA/CISD1 1.24605741388385 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 8/149 362/9376 1.39063369053358 CSH1/HSP90AA1/NR4A1/CCND1/RPS6/GNG5/AREG/COL9A3 0.963193885958043 Human Diseases Infectious disease: parasitic hsa05142 Chagas disease 3/149 103/9376 1.83280119893139 FOS/JUN/SERPINE1 1.07993678959886 Metabolism Amino acid metabolism hsa00360 Phenylalanine metabolism 1/149 16/9376 3.93288590604027 MIF 1.49198943422366 Human Diseases Cancer: overview hsa05203 Viral carcinogenesis 5/149 205/9376 1.53478474382059 HLA-C/JUN/CCND1/CDKN2A/EGR2 0.983775732378075 Human Diseases Neurodegenerative disease hsa05014 Amyotrophic lateral sclerosis 8/149 368/9376 1.36796031514444 NDUFA4L2/GPX8/HSPA5/HNRNPA1/SRSF7/MT-CO3/COX6C/COX7C 0.915080318834382 Human Diseases Endocrine and metabolic disease hsa04934 Cushing syndrome 4/149 155/9376 1.62390127733276 NR4A1/CCND1/CDKN2A/KCNK3 0.995270713719576 Metabolism Metabolism of other amino acids hsa00480 Glutathione metabolism 2/149 59/9376 2.1330906609032 GPX8/PRDX6 1.10943312882653 Organismal Systems Immune system hsa04659 Th17 cell differentiation 3/149 109/9376 1.73191305954067 FOS/HSP90AA1/JUN 0.976678608803536 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 5/149 214/9376 1.47023772188421 FOS/HLA-C/JUN/BST2/GNG5 0.884255398258902 Human Diseases Cancer: overview hsa05207 Chemical carcinogenesis - receptor activation 5/149 217/9376 1.44991185476139 FOS/HSP90AA1/JUN/KLF4/CCND1 0.852082775064 Human Diseases Neurodegenerative disease hsa05020 Prion disease 6/149 275/9376 1.37293471629042 EGR1/NDUFA4L2/HSPA5/MT-CO3/COX6C/COX7C 0.797633003356933 Organismal Systems Endocrine system hsa04927 Cortisol synthesis and secretion 2/149 65/9376 1.93618998451213 NR4A1/KCNK3 0.962434134751518 Metabolism Carbohydrate metabolism hsa00010 Glycolysis / Gluconeogenesis 2/149 67/9376 1.87839326855655 LDHA/ALDOA 0.916903007537065 Metabolism Amino acid metabolism hsa00340 Histidine metabolism 1/149 22/9376 2.86028065893838 AOC1 1.11004258603259 Human Diseases Cardiovascular disease hsa05416 Viral myocarditis 2/149 70/9376 1.79789069990412 HLA-C/CCND1 0.851450512132626 Organismal Systems Excretory system hsa04964 Proximal tubule bicarbonate reclamation 1/149 23/9376 2.73592063028888 ATP1B1 1.05917281964849 Organismal Systems Environmental adaptation hsa04714 Thermogenesis 5/149 235/9376 1.33885477652435 NDUFA4L2/RPS6/MT-CO3/COX6C/COX7C 0.66849659672083 Human Diseases Infectious disease: viral hsa05168 Herpes simplex virus 1 infection 4/149 180/9376 1.39835943325876 HLA-C/BST2/SOCS3/SRSF7 0.68574143069177 Human Diseases Cancer: specific types hsa05218 Melanoma 2/149 73/9376 1.72400478072998 CCND1/CDKN2A 0.789114212882549 Human Diseases Cancer: specific types hsa05223 Non-small cell lung cancer 2/149 73/9376 1.72400478072998 CCND1/CDKN2A 0.789114212882549 Human Diseases Cancer: specific types hsa05214 Glioma 2/149 76/9376 1.65595196043801 CCND1/CDKN2A 0.729601752237241 Organismal Systems Endocrine system hsa04926 Relaxin signaling pathway 3/149 130/9376 1.4521424883841 FOS/JUN/GNG5 0.659657590088124 Human Diseases Cancer: specific types hsa05212 Pancreatic cancer 2/149 77/9376 1.63444609082193 CCND1/CDKN2A 0.710346878923356 Human Diseases Cancer: specific types hsa05220 Chronic myeloid leukemia 2/149 77/9376 1.63444609082193 CCND1/CDKN2A 0.710346878923356 Human Diseases Infectious disease: bacterial hsa05133 Pertussis 2/149 78/9376 1.61349165376011 FOS/JUN 0.691368679660384 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 5/149 248/9376 1.26867287291622 FOS/HSP90AA1/RPS3/JUN/RHOB 0.544891905070072 Cellular Processes Cell growth and death hsa04210 Apoptosis 3/149 137/9376 1.37794542693382 FOS/CTSC/JUN 0.566272415953897 Organismal Systems Endocrine system hsa04910 Insulin signaling pathway 3/149 138/9376 1.36796031514444 PPP1R3C/RPS6/SOCS3 0.553350183738646 Metabolism Carbohydrate metabolism hsa00030 Pentose phosphate pathway 1/149 31/9376 2.02987659666594 ALDOA 0.72983535082241 Genetic Information Processing Folding, sorting and degradation hsa04120 Ubiquitin mediated proteolysis 3/149 142/9376 1.32942622176009 RPS27A/UBA52/SOCS3 0.502638689601744 Environmental Information Processing Signal transduction hsa04012 ErbB signaling pathway 2/149 86/9376 1.4633994068987 JUN/AREG 0.548586801078098 Metabolism Carbohydrate metabolism hsa00640 Propanoate metabolism 1/149 32/9376 1.96644295302013 LDHA 0.695878325996527 Organismal Systems Immune system hsa04610 Complement and coagulation cascades 2/149 88/9376 1.43014032946919 CLU/SERPINE1 0.515156172982842 Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 4/149 205/9376 1.22782779505647 NDUFA4L2/MT-CO3/COX6C/COX7C 0.419105927249404 Human Diseases Cancer: specific types hsa05224 Breast cancer 3/149 148/9376 1.27553056412117 FOS/JUN/CCND1 0.429334074719666 Human Diseases Cancer: overview hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer 2/149 90/9376 1.39835943325876 FOS/JUN 0.482536903529994 Organismal Systems Environmental adaptation hsa04710 Circadian rhythm 1/149 34/9376 1.8507698381366 BHLHE40 0.631509842703638 Organismal Systems Immune system hsa04662 B cell receptor signaling pathway 2/149 91/9376 1.38299284608009 FOS/JUN 0.466518548896031 Metabolism Carbohydrate metabolism hsa00051 Fructose and mannose metabolism 1/149 35/9376 1.79789069990412 ALDOA 0.600937424376916 Organismal Systems Immune system hsa04658 Th1 and Th2 cell differentiation 2/149 93/9376 1.35325106444396 FOS/JUN 0.435040100252061 Organismal Systems Endocrine system hsa04912 GnRH signaling pathway 2/149 93/9376 1.35325106444396 EGR1/JUN 0.435040100252061 Organismal Systems Endocrine system hsa04921 Oxytocin signaling pathway 3/149 154/9376 1.22583456811645 FOS/JUN/CCND1 0.359076292978785 Human Diseases Immune disease hsa05323 Rheumatoid arthritis 2/149 95/9376 1.32476156835041 FOS/JUN 0.404275626175438 Metabolism Amino acid metabolism hsa00350 Tyrosine metabolism 1/149 37/9376 1.70070741882822 MIF 0.542670110730247 Human Diseases Cancer: specific types hsa05216 Thyroid cancer 1/149 37/9376 1.70070741882822 CCND1 0.542670110730247 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 4/149 216/9376 1.16529952771564 FOS/HSP90AA1/JUN/HSPA5 0.312319617119097 Organismal Systems Excretory system hsa04960 Aldosterone-regulated sodium reabsorption 1/149 38/9376 1.65595196043801 ATP1B1 0.514855563406842 Organismal Systems Environmental adaptation hsa04713 Circadian entrainment 2/149 97/9376 1.29744689683803 FOS/GNG5 0.374190910929884 Human Diseases Immune disease hsa05330 Allograft rejection 1/149 39/9376 1.61349165376011 HLA-C 0.487849422204016 Human Diseases Cancer: overview hsa05231 Choline metabolism in cancer 2/149 99/9376 1.27123584841706 FOS/JUN 0.344754083908325 Human Diseases Infectious disease: viral hsa05161 Hepatitis B 3/149 163/9376 1.15815045085848 FOS/JUN/EGR2 0.258828570094988 Environmental Information Processing Signal transduction hsa04024 cAMP signaling pathway 4/149 226/9376 1.11373760171052 FOS/ATP1B1/JUN/EDNRA 0.219935963953374 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 4/149 227/9376 1.10883126866334 HLA-C/CCND1/GNG5/CDKN2A 0.21092512674198 Organismal Systems Digestive system hsa04974 Protein digestion and absorption 2/149 103/9376 1.22186746595426 ATP1B1/COL9A3 0.287707125309765 Metabolism Amino acid metabolism hsa00380 Tryptophan metabolism 1/149 42/9376 1.4982422499201 AOC1 0.411225285761327 Cellular Processes Cell growth and death hsa04216 Ferroptosis 1/149 42/9376 1.4982422499201 FTH1 0.411225285761327 Human Diseases Neurodegenerative disease hsa05022 Pathways of neurodegeneration - multiple diseases 8/149 480/9376 1.04876957494407 RPS27A/NDUFA4L2/GPX8/HSPA5/UBA52/MT-CO3/COX6C/COX7C 0.139386500341619 Organismal Systems Immune system hsa04625 C-type lectin receptor signaling pathway 2/149 105/9376 1.19859379993608 JUN/EGR2 0.26004323304904 Environmental Information Processing Signal transduction hsa04630 JAK-STAT signaling pathway 3/149 168/9376 1.12368168744008 CSH1/CCND1/SOCS3 0.205553984440923 Human Diseases Cancer: specific types hsa05215 Prostate cancer 2/149 106/9376 1.18728631125744 HSP90AA1/CCND1 0.246415268135239 Human Diseases Endocrine and metabolic disease hsa04940 Type I diabetes mellitus 1/149 44/9376 1.43014032946919 HLA-C 0.363410648531786 Human Diseases Immune disease hsa05332 Graft-versus-host disease 1/149 45/9376 1.39835943325876 HLA-C 0.340381368562046 Organismal Systems Immune system hsa04620 Toll-like receptor signaling pathway 2/149 109/9376 1.15460870636045 FOS/JUN 0.206312777547378 Human Diseases Endocrine and metabolic disease hsa04931 Insulin resistance 2/149 109/9376 1.15460870636045 PPP1R3C/SOCS3 0.206312777547378 Environmental Information Processing Signal transduction hsa04010 MAPK signaling pathway 5/149 300/9376 1.04876957494407 FOS/JUN/NR4A1/DUSP1/AREG 0.109096512162091 Metabolism Metabolism of cofactors and vitamins hsa00860 Porphyrin metabolism 1/149 46/9376 1.36796031514444 FTH1 0.317897848168346 Metabolism Carbohydrate metabolism hsa00620 Pyruvate metabolism 1/149 47/9376 1.33885477652435 LDHA 0.29593307469004 Human Diseases Endocrine and metabolic disease hsa04930 Type II diabetes mellitus 1/149 47/9376 1.33885477652435 SOCS3 0.29593307469004 Organismal Systems Digestive system hsa04973 Carbohydrate digestion and absorption 1/149 48/9376 1.31096196868009 ATP1B1 0.274461946592315 Environmental Information Processing Signal transduction hsa04310 Wnt signaling pathway 3/149 178/9376 1.06055350275243 JUN/CCND1/NOTUM 0.103645650322457 Human Diseases Neurodegenerative disease hsa05016 Huntington disease 5/149 308/9376 1.02152880676371 NDUFA4L2/GPX8/MT-CO3/COX6C/COX7C 0.0488189095257945 Organismal Systems Nervous system hsa04725 Cholinergic synapse 2/149 115/9376 1.09436825211555 FOS/GNG5 0.129388119604569 Organismal Systems Nervous system hsa04726 Serotonergic synapse 2/149 115/9376 1.09436825211555 GNG5/DUSP1 0.129388119604569 Organismal Systems Endocrine system hsa04928 Parathyroid hormone synthesis, secretion and action 2/149 115/9376 1.09436825211555 EGR1/FOS 0.129388119604569 Metabolism Amino acid metabolism hsa00330 Arginine and proline metabolism 1/149 50/9376 1.25852348993289 AOC1 0.232908757602677 Organismal Systems Excretory system hsa04961 Endocrine and other factor-regulated calcium reabsorption 1/149 53/9376 1.18728631125744 ATP1B1 0.173745930298098 Human Diseases Immune disease hsa05320 Autoimmune thyroid disease 1/149 54/9376 1.16529952771564 HLA-C 0.15479696996689 Organismal Systems Immune system hsa04660 T cell receptor signaling pathway 2/149 122/9376 1.03157663109253 FOS/JUN 0.0446097175178267 Organismal Systems Endocrine system hsa04919 Thyroid hormone signaling pathway 2/149 122/9376 1.03157663109253 ATP1B1/CCND1 0.0446097175178267 Human Diseases Neurodegenerative disease hsa05010 Alzheimer disease 6/149 388/9376 0.97308517262852 NDUFA4L2/APOE/MT-CO3/SLC39A4/COX6C/COX7C -0.0688057038234497 Environmental Information Processing Signal transduction hsa04340 Hedgehog signaling pathway 1/149 56/9376 1.12368168744008 CCND1 0.117961414410983 Human Diseases Infectious disease: bacterial hsa05134 Legionellosis 1/149 56/9376 1.12368168744008 EEF1A1 0.117961414410983 Human Diseases Cancer: specific types hsa05213 Endometrial cancer 1/149 59/9376 1.0665453304516 CCND1 0.0651559462266361 Human Diseases Infectious disease: bacterial hsa05130 Pathogenic Escherichia coli infection 3/149 200/9376 0.943892617449664 FOS/RPS3/JUN -0.101919390192206 Environmental Information Processing Signal transduction hsa04068 FoxO signaling pathway 2/149 133/9376 0.946258263107433 KLF2/CCND1 -0.079319424486952 Organismal Systems Nervous system hsa04728 Dopaminergic synapse 2/149 133/9376 0.946258263107433 FOS/GNG5 -0.079319424486952 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 3/149 203/9376 0.92994346546765 JUN/CCND1/COL9A3 -0.128229953473162 Organismal Systems Circulatory system hsa04270 Vascular smooth muscle contraction 2/149 134/9376 0.939196634278273 PPP1R14A/EDNRA -0.0900835617594724 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 3/149 205/9376 0.920870846292356 HLA-C/JUN/CCND1 -0.145563877879266 Human Diseases Infectious disease: bacterial hsa05135 Yersinia infection 2/149 138/9376 0.911973543429628 FOS/JUN -0.132376927381305 Organismal Systems Endocrine system hsa04929 GnRH secretion 1/149 65/9376 0.968094992256066 KISS1 -0.0327993986586763 Human Diseases Immune disease hsa05321 Inflammatory bowel disease 1/149 66/9376 0.953426886312792 JUN -0.0482481775267277 Human Diseases Cancer: specific types hsa05221 Acute myeloid leukemia 1/149 68/9376 0.925384919068298 CCND1 -0.078469592183088 Organismal Systems Endocrine system hsa04924 Renin secretion 1/149 69/9376 0.911973543429628 EDNRA -0.0932569957304346 Organismal Systems Endocrine system hsa04920 Adipocytokine signaling pathway 1/149 70/9376 0.898945349952061 SOCS3 -0.107838120618576 Human Diseases Cancer: overview hsa05204 Chemical carcinogenesis - DNA adducts 1/149 70/9376 0.898945349952061 SULT1A1 -0.107838120618576 Human Diseases Cancer: specific types hsa05211 Renal cell carcinoma 1/149 70/9376 0.898945349952061 JUN -0.107838120618576 Human Diseases Infectious disease: bacterial hsa05120 Epithelial cell signaling in Helicobacter pylori infection 1/149 71/9376 0.886284147840061 JUN -0.122219501476455 Human Diseases Cancer: overview hsa05230 Central carbon metabolism in cancer 1/149 71/9376 0.886284147840061 LDHA -0.122219501476455 Organismal Systems Nervous system hsa04723 Retrograde endocannabinoid signaling 2/149 149/9376 0.84464663753885 NDUFA4L2/GNG5 -0.242902532927318 Genetic Information Processing Information processing in viruses hsa03250 Viral life cycle - HIV-1 1/149 73/9376 0.86200239036499 BST2 -0.150407674099899 Metabolism Global and overview maps hsa01230 Biosynthesis of amino acids 1/149 75/9376 0.839015659955257 ALDOA -0.177868053812815 Human Diseases Drug resistance: antineoplastic hsa01524 Platinum drug resistance 1/149 75/9376 0.839015659955257 CDKN2A -0.177868053812815 Organismal Systems Endocrine system hsa03320 PPAR signaling pathway 1/149 76/9376 0.827975980219004 ANGPTL4 -0.191338747086449 Organismal Systems Digestive system hsa04971 Gastric acid secretion 1/149 76/9376 0.827975980219004 ATP1B1 -0.191338747086449 NA NA hsa04518 Integrin signaling 2/149 154/9376 0.817223045410965 CCND1/COL9A3 -0.29061481527461 Cellular Processes Transport and catabolism hsa04145 Phagosome 2/149 155/9376 0.811950638666378 HLA-C/SEC61B -0.29998339299633 Human Diseases Infectious disease: viral hsa05160 Hepatitis C 2/149 156/9376 0.806745826880055 CCND1/SOCS3 -0.309295948786261 Genetic Information Processing Folding, sorting and degradation hsa03018 RNA degradation 1/149 78/9376 0.806745826880055 BTG2 -0.217785982400732 Cellular Processes Cell growth and death hsa04110 Cell cycle 2/149 158/9376 0.796533854387902 CCND1/CDKN2A -0.327756159216787 Human Diseases Drug resistance: antineoplastic hsa01521 EGFR tyrosine kinase inhibitor resistance 1/149 80/9376 0.786577181208054 RPS6 -0.243605057037682 Environmental Information Processing Signaling molecules and interaction hsa04514 Cell adhesion molecule (CAM) interaction 2/149 160/9376 0.786577181208054 VCAN/HLA-C -0.346001611850609 Environmental Information Processing Signal transduction hsa04022 cGMP-PKG signaling pathway 2/149 166/9376 0.758146680682461 ATP1B1/EDNRA -0.399507367974553 Organismal Systems Endocrine system hsa04911 Insulin secretion 1/149 86/9376 0.731699703449352 ATP1B1 -0.317622334473981 Cellular Processes Cell growth and death hsa04217 Necroptosis 2/149 168/9376 0.749121124960051 HSP90AA1/FTH1 -0.416950588594636 Cellular Processes Transport and catabolism hsa04140 Autophagy - animal 2/149 169/9376 0.744688455581589 RPS27A/UBA52 -0.42560159372527 Cellular Processes Cellular community - eukaryotes hsa04530 Tight junction 2/149 170/9376 0.740307935254639 JUN/CCND1 -0.434206346413673 Human Diseases Cancer: specific types hsa05225 Hepatocellular carcinoma 2/149 170/9376 0.740307935254639 CCND1/CDKN2A -0.434206346413673 Environmental Information Processing Signaling molecules and interaction hsa04512 ECM-receptor interaction 1/149 89/9376 0.707035668501621 COL9A3 -0.352874715270026 Organismal Systems Nervous system hsa04727 GABAergic synapse 1/149 89/9376 0.707035668501621 GNG5 -0.352874715270026 Organismal Systems Digestive system hsa04976 Bile secretion 1/149 90/9376 0.699179716629381 ATP1B1 -0.364386721984275 Human Diseases Substance dependence hsa05032 Morphine addiction 1/149 91/9376 0.691496423040047 GNG5 -0.375784149823243 Human Diseases Infectious disease: bacterial hsa05131 Shigellosis 3/149 253/9376 0.746160171896968 RPS27A/JUN/UBA52 -0.520115384839202 Cellular Processes Cellular community - eukaryotes hsa04520 Adherens junction 1/149 93/9376 0.676625532221982 LMO7 -0.398246106073439 Organismal Systems Digestive system hsa04970 Salivary secretion 1/149 93/9376 0.676625532221982 ATP1B1 -0.398246106073439 Human Diseases Cancer: specific types hsa05222 Small cell lung cancer 1/149 93/9376 0.676625532221982 CCND1 -0.398246106073439 Human Diseases Infectious disease: bacterial hsa05150 Staphylococcus aureus infection 1/149 99/9376 0.635617924208528 KRT19 -0.463147513373468 Organismal Systems Immune system hsa04621 NOD-like receptor signaling pathway 2/149 187/9376 0.673007213867853 HSP90AA1/JUN -0.573949076322376 Organismal Systems Digestive system hsa04972 Pancreatic secretion 1/149 102/9376 0.616923279378866 ATP1B1 -0.494311612486197 Human Diseases Substance dependence hsa05034 Alcoholism 2/149 191/9376 0.65891282195439 FOSB/GNG5 -0.605188977344366 Organismal Systems Endocrine system hsa04922 Glucagon signaling pathway 1/149 107/9376 0.588095088753685 LDHA -0.54452889481625 Genetic Information Processing Translation hsa03013 Nucleocytoplasmic transport 1/149 108/9376 0.582649763857818 EEF1A1 -0.554329563310633 Organismal Systems Endocrine system hsa04914 Progesterone-mediated oocyte maturation 1/149 110/9376 0.572056131787675 HSP90AA1 -0.573700878247727 Human Diseases Cancer: overview hsa05202 Transcriptional misregulation in cancer 2/149 201/9376 0.626131089518849 NFKBIZ/ID2 -0.680867895586369 Human Diseases Cancer: overview hsa05205 Proteoglycans in cancer 2/149 204/9376 0.616923279378866 CCND1/RPS6 -0.702938505503399 Metabolism Global and overview maps hsa01200 Carbon metabolism 1/149 116/9376 0.542467021522796 ALDOA -0.630078145744006 Organismal Systems Nervous system hsa04724 Glutamatergic synapse 1/149 116/9376 0.542467021522796 GNG5 -0.630078145744006 Organismal Systems Nervous system hsa04722 Neurotrophin signaling pathway 1/149 120/9376 0.524384787472036 JUN -0.666320537191635 Environmental Information Processing Signal transduction hsa04152 AMPK signaling pathway 1/149 122/9376 0.515788315546265 CCND1 -0.684067480125282 NA NA hsa04382 Cornified envelope formation 2/149 217/9376 0.579964741904556 S100A11/KRT19 -0.795499839701944 NA NA hsa04081 Hormone signaling 2/149 219/9376 0.574668260243327 CSH1/GNG5 -0.809322761908083 Organismal Systems Immune system hsa04650 Natural killer cell mediated cytotoxicity 1/149 133/9376 0.473129131553716 HLA-C -0.777628273303536 Human Diseases Cancer: overview hsa05206 MicroRNAs in cancer 3/149 323/9376 0.584453633095767 CCND1/CDKN2A/SOX4 -0.965768425749074 Human Diseases Endocrine and metabolic disease hsa04936 Alcoholic liver disease 1/149 144/9376 0.436987322893363 CCND1 -0.865167175702442 Genetic Information Processing Transcription hsa03040 Spliceosome 2/149 243/9376 0.517910901206949 HNRNPA1/SRSF7 -0.967547357631623 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 3/149 333/9376 0.566902472942741 HLA-C/CCND1/COL9A3 -1.02258652929265 Cellular Processes Transport and catabolism hsa04142 Lysosome biogenesis 2/149 250/9376 0.503409395973154 CTSC/LAPTM4A -1.01129249028673 Cellular Processes Transport and catabolism hsa04144 Endocytosis 2/149 250/9376 0.503409395973154 HLA-C/ARF4 -1.01129249028673 Human Diseases Cancer: specific types hsa05226 Gastric cancer 1/149 150/9376 0.419507829977629 CCND1 -0.910717711221437 Organismal Systems Circulatory system hsa04261 Adrenergic signaling in cardiomyocytes 1/149 154/9376 0.408611522705482 ATP1B1 -0.940305923528005 Cellular Processes Transport and catabolism hsa04148 Efferocytosis 1/149 157/9376 0.400803659214295 BSG -0.962111893420772 Environmental Information Processing Signal transduction hsa04150 mTOR signaling pathway 1/149 158/9376 0.398266927193951 RPS6 -0.969309760222338 Environmental Information Processing Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction 3/149 370/9376 0.510212225648467 CSH1/KISS1/EDNRA -1.22149401467558 Human Diseases Infectious disease: viral hsa05164 Influenza A 1/149 173/9376 0.363735112697366 SOCS3 -1.07335852440151 Organismal Systems Development and regeneration hsa04360 Axon guidance 1/149 184/9376 0.34199007878611 SEMA4A -1.14547300179236 Organismal Systems Immune system hsa04062 Chemokine signaling pathway 1/149 193/9376 0.326042354904893 GNG5 -1.20217440841094 Cellular Processes Cell motility hsa04814 Motor proteins 1/149 194/9376 0.324361724209507 TNNT3 -1.2083562084517 NA NA hsa04082 Neuroactive ligand signaling 1/149 199/9376 0.316211932143941 GNG5 -1.23892838318913 Environmental Information Processing Signal transduction hsa04015 Rap1 signaling pathway 1/149 212/9376 0.29682157781436 ID1 -1.31595014953895 Environmental Information Processing Signal transduction hsa04014 Ras signaling pathway 1/149 238/9376 0.264395691162371 GNG5 -1.46068200255675 Environmental Information Processing Signal transduction hsa04020 Calcium signaling pathway 1/149 254/9376 0.247740844474978 EDNRA -1.54449966547337 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 1/149 298/9376 0.211161659384712 CSH1 -1.7585291259199 NA NA hsa04517 IgSF CAM signaling 1/149 299/9376 0.210455433099145 LMO7 -1.76315132525212 NA NA hsa04519 Cadherin signaling 1/149 404/9376 0.155757857664961 KRT19 -2.20425375548494