ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 68/198 175/18639 0.388571428571429 36.5787012987013 2.48855974739239e-91 1.03524085491523e-88 GO:0019843 rRNA binding 14/198 65/18639 0.215384615384615 20.2755244755245 5.56264456826544e-15 1.15703007019921e-12 GO:1990948 ubiquitin ligase inhibitor activity 8/198 11/18639 0.727272727272727 68.4628099173554 2.25947572556899e-14 3.13313967278901e-12 GO:0055105 ubiquitin-protein transferase inhibitor activity 8/198 15/18639 0.533333333333333 50.2060606060606 8.49684737925408e-13 8.83672127442424e-11 GO:0055106 ubiquitin-protein transferase regulator activity 9/198 36/18639 0.25 23.5340909090909 1.05488067653068e-10 7.51343998844452e-09 GO:0004857 enzyme inhibitor activity 23/198 416/18639 0.0552884615384615 5.20465472027972 1.08366922910258e-10 7.51343998844452e-09 GO:0048027 mRNA 5'-UTR binding 7/198 24/18639 0.291666666666667 27.4564393939394 4.07708106241144e-09 2.42295103137594e-07 GO:0031625 ubiquitin protein ligase binding 14/198 302/18639 0.0463576158940397 4.3639373871162 4.4961201942827e-06 0.0002337982501027 GO:0097371 MDM2/MDM4 family protein binding 4/198 12/18639 0.333333333333333 31.3787878787879 5.72072347675576e-06 0.000264424551814489 GO:0044389 ubiquitin-like protein ligase binding 14/198 322/18639 0.0434782608695652 4.09288537549407 9.34608347166813e-06 0.000388797072421394 GO:0045296 cadherin binding 14/198 334/18639 0.0419161676646707 3.94583560152422 1.41046512194979e-05 0.000533412264301011 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 13/198 349/18639 0.0372492836676218 3.5065121125293 9.58333418855081e-05 0.00332222251869761 GO:0140297 DNA-binding transcription factor binding 15/198 488/18639 0.0307377049180328 2.89353576751118 0.000235202503908385 0.00752648012506831 GO:0031386 protein tag activity 3/198 15/18639 0.2 18.8272727272727 0.000488935575224105 0.0135598132862152 GO:0141047 molecular tag activity 3/198 15/18639 0.2 18.8272727272727 0.000488935575224105 0.0135598132862152 GO:0019207 kinase regulator activity 10/198 287/18639 0.0348432055749129 3.28001267025657 0.00102501687771736 0.0266504388206514 GO:0043022 ribosome binding 6/198 112/18639 0.0535714285714286 5.04301948051948 0.00125397711250149 0.0306855575765069 GO:0019887 protein kinase regulator activity 9/198 255/18639 0.0352941176470588 3.32245989304813 0.00166348595031844 0.0373613797163532 GO:0051082 unfolded protein binding 6/198 121/18639 0.0495867768595041 4.6679188580015 0.00186249423638778 0.0373613797163532 GO:0008135 translation factor activity, RNA binding 5/198 83/18639 0.0602409638554217 5.67086527929901 0.00191009299188563 0.0373613797163532 GO:0004860 protein kinase inhibitor activity 5/198 84/18639 0.0595238095238095 5.60335497835498 0.00201375929809243 0.0373613797163532 GO:0180051 translation factor activity 5/198 84/18639 0.0595238095238095 5.60335497835498 0.00201375929809243 0.0373613797163532 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 13/198 484/18639 0.0268595041322314 2.52845604808415 0.00206565320547145 0.0373613797163532 GO:0030414 peptidase inhibitor activity 7/198 169/18639 0.0414201183431953 3.89913932221625 0.00222571471843225 0.0385790551194924 GO:0001216 DNA-binding transcription activator activity 13/198 491/18639 0.0264765784114053 2.49240881318274 0.00233988245052909 0.0389356439768041 GO:0050750 low-density lipoprotein particle receptor binding 3/198 26/18639 0.115384615384615 10.8618881118881 0.00256384659334112 0.041021545493458 GO:0019210 kinase inhibitor activity 5/198 90/18639 0.0555555555555556 5.22979797979798 0.00272407289856115 0.0419709009556088 GO:0043021 ribonucleoprotein complex binding 7/198 177/18639 0.0395480225988701 3.72290703646636 0.00288332274332861 0.0420259475817345 GO:0061134 peptidase regulator activity 8/198 226/18639 0.0353982300884956 3.33226065969429 0.00292969346122669 0.0420259475817345 GO:0051087 protein-folding chaperone binding 6/198 134/18639 0.0447761194029851 4.21506105834464 0.0031065947123057 0.0430781133439724 GO:0035925 mRNA 3'-UTR AU-rich region binding 3/198 30/18639 0.1 9.41363636363636 0.00388083585806936 0.0520783134502211 GO:0070325 lipoprotein particle receptor binding 3/198 31/18639 0.0967741935483871 9.1099706744868 0.00426337425481573 0.0554238653126045 GO:0043425 bHLH transcription factor binding 3/198 32/18639 0.09375 8.82528409090909 0.00466800938482657 0.0584472393388919 GO:0030957 Tat protein binding 2/198 10/18639 0.2 18.8272727272727 0.00477693783058251 0.0584472393388919 GO:0140416 transcription regulator inhibitor activity 3/198 33/18639 0.0909090909090909 8.55785123966942 0.00509509694047823 0.0605588664925412 GO:1990841 promoter-specific chromatin binding 4/198 68/18639 0.0588235294117647 5.53743315508021 0.00592377934241539 0.0684525612901334 GO:0004859 phospholipase inhibitor activity 2/198 12/18639 0.166666666666667 15.6893939393939 0.00690898025375225 0.0776793455557009 GO:0004866 endopeptidase inhibitor activity 6/198 161/18639 0.0372670807453416 3.5081874647092 0.00754020346641643 0.0825453853165588 GO:0098631 cell adhesion mediator activity 4/198 76/18639 0.0526315789473684 4.95454545454545 0.00874135995252274 0.0930462501402532 GO:0005201 extracellular matrix structural constituent 6/198 168/18639 0.0357142857142857 3.36201298701299 0.00919941699791665 0.0930462501402532 GO:0008191 metalloendopeptidase inhibitor activity 2/198 14/18639 0.142857142857143 13.4480519480519 0.00939409256223711 0.0930462501402532 GO:0044548 S100 protein binding 2/198 14/18639 0.142857142857143 13.4480519480519 0.00939409256223711 0.0930462501402532 GO:0035198 miRNA binding 3/198 42/18639 0.0714285714285714 6.72402597402597 0.00999890304618751 0.0967335736561396 GO:0048156 tau protein binding 3/198 43/18639 0.0697674418604651 6.5676532769556 0.0106661258444209 0.0995082789568771 GO:0005523 tropomyosin binding 2/198 15/18639 0.133333333333333 12.5515151515152 0.0107641167140853 0.0995082789568771 GO:0019841 retinol binding 2/198 16/18639 0.125 11.7670454545455 0.0122165516523135 0.108129478454519 GO:0055102 lipase inhibitor activity 2/198 16/18639 0.125 11.7670454545455 0.0122165516523135 0.108129478454519 GO:0005504 fatty acid binding 3/198 47/18639 0.0638297872340425 6.00870406189555 0.0135886057955738 0.11601917900501 GO:0051787 misfolded protein binding 2/198 17/18639 0.117647058823529 11.0748663101604 0.0137495101720926 0.11601917900501 GO:0061135 endopeptidase regulator activity 6/198 184/18639 0.0326086956521739 3.06966403162055 0.013944612861179 0.11601917900501 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 3/198 48/18639 0.0625 5.88352272727273 0.0143833006179799 0.117322608962346 GO:0003746 translation elongation factor activity 2/198 18/18639 0.111111111111111 10.459595959596 0.0153611355099075 0.120570422115501 GO:0098641 cadherin binding involved in cell-cell adhesion 2/198 18/18639 0.111111111111111 10.459595959596 0.0153611355099075 0.120570422115501 GO:0003743 translation initiation factor activity 3/198 51/18639 0.0588235294117647 5.53743315508021 0.0169228550239123 0.128956981467292 GO:0016918 retinal binding 2/198 19/18639 0.105263157894737 9.90909090909091 0.0170496009151468 0.128956981467292 GO:0004867 serine-type endopeptidase inhibitor activity 4/198 95/18639 0.0421052631578947 3.96363636363636 0.0185839970201461 0.137302691904401 GO:0043024 ribosomal small subunit binding 2/198 20/18639 0.1 9.41363636363636 0.0188131092272857 0.137302691904401 GO:0098632 cell-cell adhesion mediator activity 3/198 55/18639 0.0545454545454545 5.13471074380165 0.0206742459683107 0.148284246945125 GO:0003730 mRNA 3'-UTR binding 7/198 262/18639 0.0267175572519084 2.51509368494101 0.0221642488804569 0.156276737868984 GO:0061980 regulatory RNA binding 3/198 58/18639 0.0517241379310345 4.86912225705329 0.0237630727796125 0.164631027943067 GO:0004602 glutathione peroxidase activity 2/198 23/18639 0.0869565217391304 8.18577075098814 0.0245363551261302 0.164631027943067 GO:0017134 fibroblast growth factor binding 2/198 23/18639 0.0869565217391304 8.18577075098814 0.0245363551261302 0.164631027943067 GO:0070412 R-SMAD binding 2/198 26/18639 0.0769230769230769 7.24125874125874 0.030873043486378 0.203860096671956 GO:0001671 ATPase activator activity 2/198 27/18639 0.0740740740740741 6.97306397306397 0.0331139309485993 0.211929158071035 GO:0023026 MHC class II protein complex binding 2/198 27/18639 0.0740740740740741 6.97306397306397 0.0331139309485993 0.211929158071035 GO:0019789 SUMO transferase activity 2/198 28/18639 0.0714285714285714 6.72402597402597 0.0354165003302538 0.219899464737098 GO:0097718 disordered domain specific binding 2/198 28/18639 0.0714285714285714 6.72402597402597 0.0354165003302538 0.219899464737098 GO:0004629 phospholipase C activity 2/198 29/18639 0.0689655172413793 6.49216300940439 0.0377792026440362 0.227770265216218 GO:0043236 laminin binding 2/198 29/18639 0.0689655172413793 6.49216300940439 0.0377792026440362 0.227770265216218 GO:0051059 NF-kappaB binding 2/198 32/18639 0.0625 5.88352272727273 0.0452129999358998 0.267667570519701 GO:0044183 protein folding chaperone 3/198 75/18639 0.04 3.76545454545455 0.045683647853122 0.267667570519701 GO:0071889 14-3-3 protein binding 2/198 33/18639 0.0606060606060606 5.70523415977962 0.0478012517420561 0.276185010065213 GO:0031072 heat shock protein binding 4/198 131/18639 0.0305343511450382 2.87439278278973 0.0511907892537742 0.289144433286313 GO:0033293 monocarboxylic acid binding 3/198 79/18639 0.0379746835443038 3.57479861910242 0.0519036606564101 0.289144433286313 GO:0005154 epidermal growth factor receptor binding 2/198 35/18639 0.0571428571428571 5.37922077922078 0.0531346516259427 0.289144433286313 GO:0000049 tRNA binding 3/198 80/18639 0.0375 3.53011363636364 0.0535195225073223 0.289144433286313 GO:0048306 calcium-dependent protein binding 3/198 80/18639 0.0375 3.53011363636364 0.0535195225073223 0.289144433286313 GO:0023023 MHC protein complex binding 2/198 37/18639 0.0540540540540541 5.08845208845209 0.0586680275292237 0.312896146822526 GO:0005501 retinoid binding 2/198 38/18639 0.0526315789473684 4.95454545454545 0.0615063363407053 0.319832948971668 GO:0019840 isoprenoid binding 2/198 38/18639 0.0526315789473684 4.95454545454545 0.0615063363407053 0.319832948971668 GO:0016209 antioxidant activity 3/198 86/18639 0.0348837209302326 3.2838266384778 0.0637129698624223 0.327217227935403 GO:0003714 transcription corepressor activity 5/198 204/18639 0.0245098039215686 2.30726381461676 0.0668914647855247 0.337409348660994 GO:0140662 ATP-dependent protein folding chaperone 2/198 40/18639 0.05 4.70681818181818 0.0673196536991887 0.337409348660994 GO:0019209 kinase activator activity 4/198 148/18639 0.027027027027027 2.54422604422604 0.0732323000447046 0.358771968087191 GO:0008307 structural constituent of muscle 2/198 42/18639 0.0476190476190476 4.48268398268398 0.0733067723255078 0.358771968087191 GO:0001046 core promoter sequence-specific DNA binding 2/198 44/18639 0.0454545454545455 4.27892561983471 0.0794578353029875 0.384354180070265 GO:0046915 transition metal ion transmembrane transporter activity 2/198 45/18639 0.0444444444444444 4.18383838383838 0.0825918575747963 0.394921985645003 GO:0030291 protein serine/threonine kinase inhibitor activity 2/198 46/18639 0.0434782608695652 4.09288537549407 0.0857633209733672 0.405426608237736 GO:0060590 ATPase regulator activity 2/198 49/18639 0.0408163265306122 3.84230055658627 0.0954910623857515 0.424915134925781 GO:0004722 protein serine/threonine phosphatase activity 3/198 103/18639 0.029126213592233 2.74183583406884 0.0969270664596211 0.424915134925781 GO:0005131 growth hormone receptor binding 1/198 10/18639 0.1 9.41363636363636 0.101315330104512 0.424915134925781 GO:0005381 iron ion transmembrane transporter activity 1/198 10/18639 0.1 9.41363636363636 0.101315330104512 0.424915134925781 GO:0008239 dipeptidyl-peptidase activity 1/198 10/18639 0.1 9.41363636363636 0.101315330104512 0.424915134925781 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/198 10/18639 0.1 9.41363636363636 0.101315330104512 0.424915134925781 GO:0031434 mitogen-activated protein kinase kinase binding 1/198 10/18639 0.1 9.41363636363636 0.101315330104512 0.424915134925781 GO:0032356 oxidized DNA binding 1/198 10/18639 0.1 9.41363636363636 0.101315330104512 0.424915134925781 GO:0035374 chondroitin sulfate binding 1/198 10/18639 0.1 9.41363636363636 0.101315330104512 0.424915134925781 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/198 10/18639 0.1 9.41363636363636 0.101315330104512 0.424915134925781 GO:0098505 G-rich strand telomeric DNA binding 1/198 10/18639 0.1 9.41363636363636 0.101315330104512 0.424915134925781 GO:0030544 Hsp70 protein binding 2/198 51/18639 0.0392156862745098 3.69162210338681 0.102143061280236 0.424915134925781 GO:0008146 sulfotransferase activity 2/198 53/18639 0.0377358490566038 3.55231560891938 0.108918660186136 0.439244815558436 GO:0016860 intramolecular oxidoreductase activity 2/198 53/18639 0.0377358490566038 3.55231560891938 0.108918660186136 0.439244815558436 GO:0051018 protein kinase A binding 2/198 53/18639 0.0377358490566038 3.55231560891938 0.108918660186136 0.439244815558436 GO:0004620 phospholipase activity 3/198 109/18639 0.0275229357798165 2.59090909090909 0.110033531114204 0.439244815558436 GO:0008199 ferric iron binding 1/198 11/18639 0.0909090909090909 8.55785123966942 0.110867080850086 0.439244815558436 GO:0140313 molecular sequestering activity 2/198 55/18639 0.0363636363636364 3.42314049586777 0.115809730313324 0.450920828679828 GO:0008179 adenylate cyclase binding 1/198 12/18639 0.0833333333333333 7.84469696969697 0.120317817267935 0.450920828679828 GO:0035259 nuclear glucocorticoid receptor binding 1/198 12/18639 0.0833333333333333 7.84469696969697 0.120317817267935 0.450920828679828 GO:0035497 cAMP response element binding 1/198 12/18639 0.0833333333333333 7.84469696969697 0.120317817267935 0.450920828679828 GO:0043047 single-stranded telomeric DNA binding 1/198 12/18639 0.0833333333333333 7.84469696969697 0.120317817267935 0.450920828679828 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/198 12/18639 0.0833333333333333 7.84469696969697 0.120317817267935 0.450920828679828 GO:0004601 peroxidase activity 2/198 57/18639 0.0350877192982456 3.3030303030303 0.122808428119045 0.456145590156454 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/198 13/18639 0.0769230769230769 7.24125874125874 0.129668602267181 0.457977879533539 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/198 13/18639 0.0769230769230769 7.24125874125874 0.129668602267181 0.457977879533539 GO:0071837 HMG box domain binding 1/198 13/18639 0.0769230769230769 7.24125874125874 0.129668602267181 0.457977879533539 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/198 13/18639 0.0769230769230769 7.24125874125874 0.129668602267181 0.457977879533539 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 2/198 59/18639 0.0338983050847458 3.19106317411402 0.129907186983071 0.457977879533539 GO:0070888 E-box binding 2/198 59/18639 0.0338983050847458 3.19106317411402 0.129907186983071 0.457977879533539 GO:0031406 carboxylic acid binding 4/198 187/18639 0.0213903743315508 2.0136120563928 0.138542057229602 0.473696088964797 GO:0031404 chloride ion binding 1/198 14/18639 0.0714285714285714 6.72402597402597 0.138920487629099 0.473696088964797 GO:0061665 SUMO ligase activity 1/198 14/18639 0.0714285714285714 6.72402597402597 0.138920487629099 0.473696088964797 GO:0098847 sequence-specific single stranded DNA binding 1/198 14/18639 0.0714285714285714 6.72402597402597 0.138920487629099 0.473696088964797 GO:0043177 organic acid binding 4/198 189/18639 0.0211640211640212 1.99230399230399 0.142379605158927 0.481391999932746 GO:0004129 cytochrome-c oxidase activity 1/198 15/18639 0.0666666666666667 6.27575757575758 0.148074514123029 0.481391999932746 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/198 15/18639 0.0666666666666667 6.27575757575758 0.148074514123029 0.481391999932746 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/198 15/18639 0.0666666666666667 6.27575757575758 0.148074514123029 0.481391999932746 GO:0031005 filamin binding 1/198 15/18639 0.0666666666666667 6.27575757575758 0.148074514123029 0.481391999932746 GO:0042826 histone deacetylase binding 3/198 127/18639 0.0236220472440945 2.22369362920544 0.152979188746103 0.481391999932746 GO:0005521 lamin binding 1/198 16/18639 0.0625 5.88352272727273 0.157131711621076 0.481391999932746 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/198 16/18639 0.0625 5.88352272727273 0.157131711621076 0.481391999932746 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/198 16/18639 0.0625 5.88352272727273 0.157131711621076 0.481391999932746 GO:0016722 oxidoreductase activity, acting on metal ions 1/198 16/18639 0.0625 5.88352272727273 0.157131711621076 0.481391999932746 GO:0017070 U6 snRNA binding 1/198 16/18639 0.0625 5.88352272727273 0.157131711621076 0.481391999932746 GO:0022841 potassium ion leak channel activity 1/198 16/18639 0.0625 5.88352272727273 0.157131711621076 0.481391999932746 GO:0043023 ribosomal large subunit binding 1/198 16/18639 0.0625 5.88352272727273 0.157131711621076 0.481391999932746 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 5/198 268/18639 0.0186567164179104 1.75627544097693 0.157378153824167 0.481391999932746 GO:0050840 extracellular matrix binding 2/198 67/18639 0.0298507462686567 2.81004070556309 0.159160745132698 0.483179924979311 GO:0016298 lipase activity 3/198 130/18639 0.0230769230769231 2.17237762237762 0.160595304204901 0.483179924979311 GO:0004659 prenyltransferase activity 1/198 17/18639 0.0588235294117647 5.53743315508021 0.166093099211638 0.483179924979311 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/198 17/18639 0.0588235294117647 5.53743315508021 0.166093099211638 0.483179924979311 GO:0038191 neuropilin binding 1/198 17/18639 0.0588235294117647 5.53743315508021 0.166093099211638 0.483179924979311 GO:0048038 quinone binding 1/198 17/18639 0.0588235294117647 5.53743315508021 0.166093099211638 0.483179924979311 GO:0070492 oligosaccharide binding 1/198 17/18639 0.0588235294117647 5.53743315508021 0.166093099211638 0.483179924979311 GO:0016782 transferase activity, transferring sulphur-containing groups 2/198 70/18639 0.0285714285714286 2.68961038961039 0.170425682477724 0.48990481511199 GO:0001217 DNA-binding transcription repressor activity 5/198 278/18639 0.0179856115107914 1.69310006540222 0.174677391787023 0.48990481511199 GO:0070064 proline-rich region binding 1/198 18/18639 0.0555555555555556 5.22979797979798 0.17495968531174 0.48990481511199 GO:0019838 growth factor binding 3/198 136/18639 0.0220588235294118 2.07653743315508 0.176160191808075 0.48990481511199 GO:0030246 carbohydrate binding 5/198 280/18639 0.0178571428571429 1.68100649350649 0.178222522779333 0.48990481511199 GO:0003756 protein disulfide isomerase activity 1/198 19/18639 0.0526315789473684 4.95454545454545 0.183732467778217 0.48990481511199 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/198 19/18639 0.0526315789473684 4.95454545454545 0.183732467778217 0.48990481511199 GO:0022840 leak channel activity 1/198 19/18639 0.0526315789473684 4.95454545454545 0.183732467778217 0.48990481511199 GO:0022842 narrow pore channel activity 1/198 19/18639 0.0526315789473684 4.95454545454545 0.183732467778217 0.48990481511199 GO:0043395 heparan sulfate proteoglycan binding 1/198 19/18639 0.0526315789473684 4.95454545454545 0.183732467778217 0.48990481511199 GO:0030295 protein kinase activator activity 3/198 139/18639 0.0215827338129496 2.03172007848267 0.184095718203032 0.48990481511199 GO:0048029 monosaccharide binding 2/198 74/18639 0.027027027027027 2.54422604422604 0.185642144299392 0.48990481511199 GO:0001972 retinoic acid binding 1/198 20/18639 0.05 4.70681818181818 0.19241243401774 0.48990481511199 GO:0016004 phospholipase activator activity 1/198 20/18639 0.05 4.70681818181818 0.19241243401774 0.48990481511199 GO:0016505 peptidase activator activity involved in apoptotic process 1/198 20/18639 0.05 4.70681818181818 0.19241243401774 0.48990481511199 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/198 20/18639 0.05 4.70681818181818 0.19241243401774 0.48990481511199 GO:0051536 iron-sulfur cluster binding 2/198 76/18639 0.0263157894736842 2.47727272727273 0.193321888507757 0.48990481511199 GO:0051540 metal cluster binding 2/198 77/18639 0.025974025974026 2.44510035419126 0.197177281455824 0.48990481511199 GO:0046982 protein heterodimerization activity 6/198 369/18639 0.016260162601626 1.53067257945307 0.199898792817291 0.48990481511199 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/198 21/18639 0.0476190476190476 4.48268398268398 0.201000561095697 0.48990481511199 GO:0070182 DNA polymerase binding 1/198 21/18639 0.0476190476190476 4.48268398268398 0.201000561095697 0.48990481511199 GO:0072542 protein phosphatase activator activity 1/198 21/18639 0.0476190476190476 4.48268398268398 0.201000561095697 0.48990481511199 GO:0046332 SMAD binding 2/198 79/18639 0.0253164556962025 2.38319907940161 0.204915884906052 0.48990481511199 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/198 22/18639 0.0454545454545455 4.27892561983471 0.209497815843954 0.48990481511199 GO:0140784 metal ion sensor activity 1/198 22/18639 0.0454545454545455 4.27892561983471 0.209497815843954 0.48990481511199 GO:0001618 virus receptor activity 2/198 81/18639 0.0246913580246914 2.32435465768799 0.212687423661733 0.48990481511199 GO:0033192 calmodulin-dependent protein phosphatase activity 2/198 81/18639 0.0246913580246914 2.32435465768799 0.212687423661733 0.48990481511199 GO:0140791 histone H2AXS140 phosphatase activity 2/198 81/18639 0.0246913580246914 2.32435465768799 0.212687423661733 0.48990481511199 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 2/198 81/18639 0.0246913580246914 2.32435465768799 0.212687423661733 0.48990481511199 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 2/198 81/18639 0.0246913580246914 2.32435465768799 0.212687423661733 0.48990481511199 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 2/198 81/18639 0.0246913580246914 2.32435465768799 0.212687423661733 0.48990481511199 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 2/198 81/18639 0.0246913580246914 2.32435465768799 0.212687423661733 0.48990481511199 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 2/198 81/18639 0.0246913580246914 2.32435465768799 0.212687423661733 0.48990481511199 GO:1990439 MAP kinase serine/threonine phosphatase activity 2/198 81/18639 0.0246913580246914 2.32435465768799 0.212687423661733 0.48990481511199 GO:0019842 vitamin binding 3/198 150/18639 0.02 1.88272727272727 0.213942260604598 0.48990481511199 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 2/198 82/18639 0.024390243902439 2.2960088691796 0.216584030929147 0.48990481511199 GO:0033549 MAP kinase phosphatase activity 2/198 82/18639 0.024390243902439 2.2960088691796 0.216584030929147 0.48990481511199 GO:0140272 exogenous protein binding 2/198 82/18639 0.024390243902439 2.2960088691796 0.216584030929147 0.48990481511199 GO:0005212 structural constituent of eye lens 1/198 23/18639 0.0434782608695652 4.09288537549407 0.217905154967492 0.48990481511199 GO:0031681 G-protein beta-subunit binding 1/198 23/18639 0.0434782608695652 4.09288537549407 0.217905154967492 0.48990481511199 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/198 23/18639 0.0434782608695652 4.09288537549407 0.217905154967492 0.48990481511199 GO:0001540 amyloid-beta binding 2/198 83/18639 0.0240963855421687 2.26834611171961 0.220487080189473 0.48990481511199 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 2/198 83/18639 0.0240963855421687 2.26834611171961 0.220487080189473 0.48990481511199 GO:0017018 myosin phosphatase activity 2/198 84/18639 0.0238095238095238 2.24134199134199 0.224395998419081 0.48990481511199 GO:0005540 hyaluronic acid binding 1/198 24/18639 0.0416666666666667 3.92234848484848 0.226223525149939 0.48990481511199 GO:0019957 C-C chemokine binding 1/198 24/18639 0.0416666666666667 3.92234848484848 0.226223525149939 0.48990481511199 GO:0030215 semaphorin receptor binding 1/198 24/18639 0.0416666666666667 3.92234848484848 0.226223525149939 0.48990481511199 GO:0035035 histone acetyltransferase binding 1/198 24/18639 0.0416666666666667 3.92234848484848 0.226223525149939 0.48990481511199 GO:0060229 lipase activator activity 1/198 24/18639 0.0416666666666667 3.92234848484848 0.226223525149939 0.48990481511199 GO:0005537 D-mannose binding 1/198 25/18639 0.04 3.76545454545455 0.234453863158014 0.48990481511199 GO:0008483 transaminase activity 1/198 25/18639 0.04 3.76545454545455 0.234453863158014 0.48990481511199 GO:0015271 outward rectifier potassium channel activity 1/198 25/18639 0.04 3.76545454545455 0.234453863158014 0.48990481511199 GO:0015662 P-type ion transporter activity 1/198 25/18639 0.04 3.76545454545455 0.234453863158014 0.48990481511199 GO:0019211 phosphatase activator activity 1/198 25/18639 0.04 3.76545454545455 0.234453863158014 0.48990481511199 GO:0120020 cholesterol transfer activity 1/198 25/18639 0.04 3.76545454545455 0.234453863158014 0.48990481511199 GO:0140358 P-type transmembrane transporter activity 1/198 25/18639 0.04 3.76545454545455 0.234453863158014 0.48990481511199 GO:0008081 phosphoric diester hydrolase activity 2/198 87/18639 0.0229885057471264 2.16405433646813 0.236152405581799 0.48990481511199 GO:0004435 phosphatidylinositol phospholipase C activity 1/198 26/18639 0.0384615384615385 3.62062937062937 0.242597095944879 0.48990481511199 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/198 26/18639 0.0384615384615385 3.62062937062937 0.242597095944879 0.48990481511199 GO:0008157 protein phosphatase 1 binding 1/198 26/18639 0.0384615384615385 3.62062937062937 0.242597095944879 0.48990481511199 GO:0008198 ferrous iron binding 1/198 26/18639 0.0384615384615385 3.62062937062937 0.242597095944879 0.48990481511199 GO:0030247 polysaccharide binding 1/198 26/18639 0.0384615384615385 3.62062937062937 0.242597095944879 0.48990481511199 GO:0050681 nuclear androgen receptor binding 1/198 26/18639 0.0384615384615385 3.62062937062937 0.242597095944879 0.48990481511199 GO:0008083 growth factor activity 3/198 162/18639 0.0185185185185185 1.74326599326599 0.247568036376797 0.497528034457718 GO:0005385 zinc ion transmembrane transporter activity 1/198 27/18639 0.037037037037037 3.48653198653199 0.250654140752429 0.501308281504858 GO:0043178 alcohol binding 2/198 92/18639 0.0217391304347826 2.04644268774704 0.255813523631538 0.505109749147435 GO:0005539 glycosaminoglycan binding 4/198 242/18639 0.0165289256198347 1.55597295266717 0.25651604911769 0.505109749147435 GO:0045499 chemorepellent activity 1/198 28/18639 0.0357142857142857 3.36201298701299 0.258625905212509 0.505109749147435 GO:0051019 mitogen-activated protein kinase binding 1/198 28/18639 0.0357142857142857 3.36201298701299 0.258625905212509 0.505109749147435 GO:0051537 2 iron, 2 sulfur cluster binding 1/198 28/18639 0.0357142857142857 3.36201298701299 0.258625905212509 0.505109749147435 GO:0003785 actin monomer binding 1/198 29/18639 0.0344827586206897 3.24608150470219 0.266513287447097 0.518081904570058 GO:0042277 peptide binding 4/198 249/18639 0.0160642570281124 1.5122307411464 0.272878697464334 0.520036297448464 GO:0003712 transcription coregulator activity 7/198 495/18639 0.0141414141414141 1.33122130394858 0.274299477013117 0.520036297448464 GO:0016769 transferase activity, transferring nitrogenous groups 1/198 30/18639 0.0333333333333333 3.13787878787879 0.274317176167435 0.520036297448464 GO:0031210 phosphatidylcholine binding 1/198 30/18639 0.0333333333333333 3.13787878787879 0.274317176167435 0.520036297448464 GO:0048019 receptor antagonist activity 1/198 30/18639 0.0333333333333333 3.13787878787879 0.274317176167435 0.520036297448464 GO:0008201 heparin binding 3/198 172/18639 0.0174418604651163 1.6419133192389 0.276172670785389 0.520036297448464 GO:0003924 GTPase activity 5/198 331/18639 0.0151057401812689 1.42199945070036 0.276269283019497 0.520036297448464 GO:0047499 calcium-independent phospholipase A2 activity 1/198 31/18639 0.032258064516129 3.0366568914956 0.282038450772134 0.52622725013457 GO:0004721 phosphoprotein phosphatase activity 3/198 175/18639 0.0171428571428571 1.61376623376623 0.28482382035147 0.52622725013457 GO:0015106 bicarbonate transmembrane transporter activity 1/198 32/18639 0.03125 2.94176136363636 0.28967798144427 0.52622725013457 GO:0031369 translation initiation factor binding 1/198 32/18639 0.03125 2.94176136363636 0.28967798144427 0.52622725013457 GO:0047498 calcium-dependent phospholipase A2 activity 1/198 32/18639 0.03125 2.94176136363636 0.28967798144427 0.52622725013457 GO:0071813 lipoprotein particle binding 1/198 32/18639 0.03125 2.94176136363636 0.28967798144427 0.52622725013457 GO:0071814 protein-lipid complex binding 1/198 32/18639 0.03125 2.94176136363636 0.28967798144427 0.52622725013457 GO:0120015 sterol transfer activity 1/198 32/18639 0.03125 2.94176136363636 0.28967798144427 0.52622725013457 GO:0019956 chemokine binding 1/198 33/18639 0.0303030303030303 2.85261707988981 0.297236629247465 0.535283280376386 GO:0030296 protein tyrosine kinase activator activity 1/198 33/18639 0.0303030303030303 2.85261707988981 0.297236629247465 0.535283280376386 GO:0015035 protein-disulfide reductase activity 1/198 34/18639 0.0294117647058824 2.76871657754011 0.304715246220968 0.539410818842224 GO:0030332 cyclin binding 1/198 34/18639 0.0294117647058824 2.76871657754011 0.304715246220968 0.539410818842224 GO:0051427 hormone receptor binding 1/198 34/18639 0.0294117647058824 2.76871657754011 0.304715246220968 0.539410818842224 GO:0090482 vitamin transmembrane transporter activity 1/198 34/18639 0.0294117647058824 2.76871657754011 0.304715246220968 0.539410818842224 GO:0008237 metallopeptidase activity 3/198 184/18639 0.016304347826087 1.53483201581028 0.310893978105793 0.54554497897935 GO:0004623 phospholipase A2 activity 1/198 35/18639 0.0285714285714286 2.68961038961039 0.312114675473763 0.54554497897935 GO:0043015 gamma-tubulin binding 1/198 35/18639 0.0285714285714286 2.68961038961039 0.312114675473763 0.54554497897935 GO:0019888 protein phosphatase regulator activity 2/198 107/18639 0.0186915887850467 1.75955819881054 0.314761455951853 0.54786931245176 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/198 36/18639 0.0277777777777778 2.61489898989899 0.319435751277687 0.55368863554799 GO:0140597 protein carrier chaperone 3/198 188/18639 0.0159574468085106 1.50217601547389 0.32251165645516 0.556700618611396 GO:0004222 metalloendopeptidase activity 2/198 110/18639 0.0181818181818182 1.71157024793388 0.326460162037842 0.559253450413122 GO:0043394 proteoglycan binding 1/198 37/18639 0.027027027027027 2.54422604422604 0.326679299159588 0.559253450413122 GO:0019902 phosphatase binding 3/198 190/18639 0.0157894736842105 1.48636363636364 0.328322405681592 0.559762790014518 GO:0042162 telomeric DNA binding 1/198 38/18639 0.0263157894736842 2.47727272727273 0.333846135992531 0.566318493857096 GO:1901681 sulfur compound binding 4/198 275/18639 0.0145454545454545 1.36925619834711 0.334890263194341 0.566318493857096 GO:0042578 phosphoric ester hydrolase activity 5/198 363/18639 0.0137741046831956 1.29664412722264 0.342618549282321 0.576686880201547 GO:0001221 transcription coregulator binding 2/198 115/18639 0.0173913043478261 1.63715415019763 0.345837101592623 0.576686880201547 GO:0015036 disulfide oxidoreductase activity 1/198 40/18639 0.025 2.35340909090909 0.347952901275453 0.576686880201547 GO:0050997 quaternary ammonium group binding 1/198 40/18639 0.025 2.35340909090909 0.347952901275453 0.576686880201547 GO:0071855 neuropeptide receptor binding 1/198 40/18639 0.025 2.35340909090909 0.347952901275453 0.576686880201547 GO:0019208 phosphatase regulator activity 2/198 117/18639 0.0170940170940171 1.60916860916861 0.353538517585335 0.583541814783649 GO:0001530 lipopolysaccharide binding 1/198 41/18639 0.024390243902439 2.2960088691796 0.354894421010248 0.583541814783649 GO:0022853 active monoatomic ion transmembrane transporter activity 2/198 118/18639 0.0169491525423729 1.59553158705701 0.357377517919547 0.585311210450911 GO:0004520 DNA endonuclease activity 1/198 42/18639 0.0238095238095238 2.24134199134199 0.361762412441583 0.585576511967699 GO:0042056 chemoattractant activity 1/198 42/18639 0.0238095238095238 2.24134199134199 0.361762412441583 0.585576511967699 GO:0051879 Hsp90 protein binding 1/198 42/18639 0.0238095238095238 2.24134199134199 0.361762412441583 0.585576511967699 GO:0005525 GTP binding 5/198 378/18639 0.0132275132275132 1.24518999519 0.374199118909389 0.598148870660925 GO:0001223 transcription coactivator binding 1/198 44/18639 0.0227272727272727 2.13946280991736 0.375280902025244 0.598148870660925 GO:0030020 extracellular matrix structural constituent conferring tensile strength 1/198 44/18639 0.0227272727272727 2.13946280991736 0.375280902025244 0.598148870660925 GO:0030547 signaling receptor inhibitor activity 1/198 44/18639 0.0227272727272727 2.13946280991736 0.375280902025244 0.598148870660925 GO:0005516 calmodulin binding 3/198 207/18639 0.0144927536231884 1.36429512516469 0.377566541373859 0.599494966456204 GO:0042605 peptide antigen binding 1/198 45/18639 0.0222222222222222 2.09191919191919 0.381932925762754 0.604122042271124 GO:0001784 phosphotyrosine residue binding 1/198 47/18639 0.0212765957446809 2.00290135396518 0.395026285284623 0.62051168611906 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 2/198 128/18639 0.015625 1.47088068181818 0.395277876974882 0.62051168611906 GO:0016763 pentosyltransferase activity 1/198 49/18639 0.0204081632653061 1.92115027829314 0.407843641589647 0.637830657523658 GO:0005048 signal sequence binding 1/198 51/18639 0.0196078431372549 1.8458110516934 0.420390783811465 0.6448988003771 GO:0005272 sodium channel activity 1/198 51/18639 0.0196078431372549 1.8458110516934 0.420390783811465 0.6448988003771 GO:0016830 carbon-carbon lyase activity 1/198 51/18639 0.0196078431372549 1.8458110516934 0.420390783811465 0.6448988003771 GO:0019001 guanyl nucleotide binding 5/198 400/18639 0.0125 1.17670454545455 0.420474899324725 0.6448988003771 GO:0032561 guanyl ribonucleotide binding 5/198 400/18639 0.0125 1.17670454545455 0.420474899324725 0.6448988003771 GO:0002020 protease binding 2/198 136/18639 0.0147058823529412 1.38435828877005 0.424856020260365 0.6448988003771 GO:0044325 transmembrane transporter binding 2/198 136/18639 0.0147058823529412 1.38435828877005 0.424856020260365 0.6448988003771 GO:0140789 histone phosphatase activity 2/198 136/18639 0.0147058823529412 1.38435828877005 0.424856020260365 0.6448988003771 GO:0016922 nuclear receptor binding 2/198 137/18639 0.0145985401459854 1.37425348374253 0.42850137469256 0.6448988003771 GO:0004864 protein phosphatase inhibitor activity 1/198 53/18639 0.0188679245283019 1.77615780445969 0.432673380263922 0.6448988003771 GO:0005246 calcium channel regulator activity 1/198 53/18639 0.0188679245283019 1.77615780445969 0.432673380263922 0.6448988003771 GO:0005544 calcium-dependent phospholipid binding 1/198 53/18639 0.0188679245283019 1.77615780445969 0.432673380263922 0.6448988003771 GO:0140296 general transcription initiation factor binding 1/198 53/18639 0.0188679245283019 1.77615780445969 0.432673380263922 0.6448988003771 GO:0070851 growth factor receptor binding 2/198 139/18639 0.0143884892086331 1.35448005232178 0.435755638422592 0.6448988003771 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 1/198 54/18639 0.0185185185185185 1.74326599326599 0.438717212756537 0.6448988003771 GO:0017069 snRNA binding 1/198 54/18639 0.0185185185185185 1.74326599326599 0.438717212756537 0.6448988003771 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 1/198 54/18639 0.0185185185185185 1.74326599326599 0.438717212756537 0.6448988003771 GO:0005085 guanyl-nucleotide exchange factor activity 3/198 230/18639 0.0130434782608696 1.22786561264822 0.442865850891659 0.648704908348346 GO:0008374 O-acyltransferase activity 1/198 55/18639 0.0181818181818182 1.71157024793388 0.444696980949929 0.649101558158494 GO:0019212 phosphatase inhibitor activity 1/198 56/18639 0.0178571428571429 1.68100649350649 0.450613360511483 0.650885965183253 GO:0030170 pyridoxal phosphate binding 1/198 56/18639 0.0178571428571429 1.68100649350649 0.450613360511483 0.650885965183253 GO:0170055 lipid transmembrane transporter activity 1/198 56/18639 0.0178571428571429 1.68100649350649 0.450613360511483 0.650885965183253 GO:0019903 protein phosphatase binding 2/198 144/18639 0.0138888888888889 1.3074494949495 0.453671791673493 0.652543918651864 GO:0016504 peptidase activator activity 1/198 57/18639 0.0175438596491228 1.65151515151515 0.456467020018491 0.652543918651864 GO:0070279 vitamin B6 binding 1/198 57/18639 0.0175438596491228 1.65151515151515 0.456467020018491 0.652543918651864 GO:0001786 phosphatidylserine binding 1/198 59/18639 0.0169491525423729 1.59553158705701 0.467988818170956 0.657714014726749 GO:0004879 nuclear receptor activity 1/198 59/18639 0.0169491525423729 1.59553158705701 0.467988818170956 0.657714014726749 GO:0036002 pre-mRNA binding 1/198 59/18639 0.0169491525423729 1.59553158705701 0.467988818170956 0.657714014726749 GO:0045309 protein phosphorylated amino acid binding 1/198 59/18639 0.0169491525423729 1.59553158705701 0.467988818170956 0.657714014726749 GO:0070063 RNA polymerase binding 1/198 59/18639 0.0169491525423729 1.59553158705701 0.467988818170956 0.657714014726749 GO:0098531 ligand-modulated transcription factor activity 1/198 60/18639 0.0166666666666667 1.56893939393939 0.473658259182913 0.659101923639653 GO:0000510 H3-H4 histone complex chaperone activity 2/198 151/18639 0.0132450331125828 1.24683925346177 0.478201770955779 0.659101923639653 GO:0140584 chromatin extrusion motor activity 2/198 151/18639 0.0132450331125828 1.24683925346177 0.478201770955779 0.659101923639653 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 2/198 151/18639 0.0132450331125828 1.24683925346177 0.478201770955779 0.659101923639653 GO:0140849 ATP-dependent H2AZ histone chaperone activity 2/198 151/18639 0.0132450331125828 1.24683925346177 0.478201770955779 0.659101923639653 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/198 61/18639 0.0163934426229508 1.54321907600596 0.479267585017553 0.659101923639653 GO:0015616 DNA translocase activity 2/198 152/18639 0.0131578947368421 1.23863636363636 0.48165140573667 0.659101923639653 GO:0140674 ATP-dependent histone chaperone activity 2/198 152/18639 0.0131578947368421 1.23863636363636 0.48165140573667 0.659101923639653 GO:0061775 cohesin loader activity 2/198 153/18639 0.0130718954248366 1.23054070112894 0.485087070392429 0.661626955027051 GO:0005507 copper ion binding 1/198 63/18639 0.0158730158730159 1.49422799422799 0.490308421385216 0.666563082667483 GO:0140104 molecular carrier activity 3/198 249/18639 0.0120481927710843 1.1341730558598 0.494753796205092 0.669572503477899 GO:0004536 DNA nuclease activity 1/198 64/18639 0.015625 1.47088068181818 0.495741180459598 0.669572503477899 GO:0120013 lipid transfer activity 1/198 65/18639 0.0153846153846154 1.44825174825175 0.501116321577714 0.67372232129009 GO:0140658 ATP-dependent chromatin remodeler activity 2/198 158/18639 0.0126582278481013 1.19159953970081 0.502052691345981 0.67372232129009 GO:0003689 DNA clamp loader activity 2/198 160/18639 0.0125 1.17670454545455 0.508738142126431 0.678317522835242 GO:0015079 potassium ion transmembrane transporter activity 2/198 160/18639 0.0125 1.17670454545455 0.508738142126431 0.678317522835242 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 1/198 68/18639 0.0147058823529412 1.38435828877005 0.516902085412089 0.684812953921749 GO:0030145 manganese ion binding 1/198 68/18639 0.0147058823529412 1.38435828877005 0.516902085412089 0.684812953921749 GO:0015081 sodium ion transmembrane transporter activity 2/198 164/18639 0.0121951219512195 1.1480044345898 0.52193305670055 0.685091333907866 GO:0140713 histone chaperone activity 2/198 164/18639 0.0121951219512195 1.1480044345898 0.52193305670055 0.685091333907866 GO:0002039 p53 binding 1/198 69/18639 0.0144927536231884 1.36429512516469 0.522052771271138 0.685091333907866 GO:0097110 scaffold protein binding 1/198 70/18639 0.0142857142857143 1.34480519480519 0.52714881603626 0.689127500964258 GO:0015399 primary active transmembrane transporter activity 2/198 166/18639 0.0120481927710843 1.1341730558598 0.528441521172111 0.689127500964258 GO:0140299 molecular sensor activity 1/198 71/18639 0.0140845070422535 1.3258642765685 0.532190796456575 0.691848035393547 GO:0005518 collagen binding 1/198 72/18639 0.0138888888888889 1.3074494949495 0.537179283224218 0.696157575767211 GO:0043539 protein serine/threonine kinase activator activity 1/198 73/18639 0.0136986301369863 1.28953922789539 0.542114841037629 0.700371968545508 GO:0003684 damaged DNA binding 1/198 74/18639 0.0135135135135135 1.27211302211302 0.546998028664181 0.704492817103093 GO:0019003 GDP binding 1/198 75/18639 0.0133333333333333 1.25515151515152 0.551829399002155 0.708521697484248 GO:0016791 phosphatase activity 3/198 273/18639 0.010989010989011 1.03446553446553 0.556687479140241 0.712559973299509 GO:0003724 RNA helicase activity 1/198 77/18639 0.012987012987013 1.22255017709563 0.561338870427425 0.714506221498917 GO:0005126 cytokine receptor binding 3/198 275/18639 0.0109090909090909 1.02694214876033 0.561643111610927 0.714506221498917 GO:0005319 lipid transporter activity 2/198 178/18639 0.0112359550561798 1.05771195097038 0.566222039524856 0.718135269641281 GO:0008186 ATP-dependent activity, acting on RNA 1/198 79/18639 0.0126582278481013 1.19159953970081 0.570647563432726 0.719270836214413 GO:0016835 carbon-oxygen lyase activity 1/198 79/18639 0.0126582278481013 1.19159953970081 0.570647563432726 0.719270836214413 GO:0016853 isomerase activity 2/198 180/18639 0.0111111111111111 1.0459595959596 0.572304439391756 0.719270836214413 GO:0019787 ubiquitin-like protein transferase activity 5/198 479/18639 0.0104384133611691 0.982634275953691 0.578307339930926 0.724626064491763 GO:0015631 tubulin binding 4/198 385/18639 0.0103896103896104 0.978040141676505 0.587150734298201 0.733205478127405 GO:0030165 PDZ domain binding 1/198 83/18639 0.0120481927710843 1.1341730558598 0.588679398304214 0.733205478127405 GO:0051117 ATPase binding 1/198 84/18639 0.0119047619047619 1.120670995671 0.593068354929337 0.736466972091355 GO:0016755 aminoacyltransferase activity 5/198 496/18639 0.0100806451612903 0.948955278592375 0.609312482538913 0.751643405170202 GO:0004197 cysteine-type endopeptidase activity 1/198 88/18639 0.0113636363636364 1.06973140495868 0.610163098881107 0.751643405170202 GO:0003727 single-stranded RNA binding 1/198 89/18639 0.0112359550561798 1.05771195097038 0.614323936917953 0.751643405170202 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/198 89/18639 0.0112359550561798 1.05771195097038 0.614323936917953 0.751643405170202 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/198 89/18639 0.0112359550561798 1.05771195097038 0.614323936917953 0.751643405170202 GO:0140793 histone H2AXY142 phosphatase activity 1/198 90/18639 0.0111111111111111 1.0459595959596 0.618440587079153 0.754461244061371 GO:0072341 modified amino acid binding 1/198 91/18639 0.010989010989011 1.03446553446553 0.622513516280637 0.757209423312119 GO:0052689 carboxylic ester hydrolase activity 1/198 92/18639 0.0108695652173913 1.02322134387352 0.626543186529528 0.759889112525608 GO:0016829 lyase activity 2/198 200/18639 0.01 0.941363636363636 0.629721683840357 0.760291312666091 GO:0051219 phosphoprotein binding 1/198 93/18639 0.010752688172043 1.01221896383187 0.630530054975484 0.760291312666091 GO:0042562 hormone binding 1/198 94/18639 0.0106382978723404 1.00145067698259 0.634474573961511 0.762836481988407 GO:0004725 protein tyrosine phosphatase activity 1/198 98/18639 0.0102040816326531 0.960575139146568 0.649838036734794 0.774592043787033 GO:0005249 voltage-gated potassium channel activity 1/198 98/18639 0.0102040816326531 0.960575139146568 0.649838036734794 0.774592043787033 GO:0042626 ATPase-coupled transmembrane transporter activity 1/198 98/18639 0.0102040816326531 0.960575139146568 0.649838036734794 0.774592043787033 GO:0008094 ATP-dependent activity, acting on DNA 2/198 210/18639 0.00952380952380952 0.896536796536797 0.656115402426926 0.779840021170289 GO:0008238 exopeptidase activity 1/198 102/18639 0.00980392156862745 0.922905525846702 0.664558879601982 0.787625338787534 GO:0008013 beta-catenin binding 1/198 106/18639 0.00943396226415094 0.888078902229846 0.678663851196976 0.802057278687335 GO:0140097 catalytic activity, acting on DNA 3/198 336/18639 0.00892857142857143 0.840503246753247 0.695836077869783 0.817775952565939 GO:0003779 actin binding 4/198 443/18639 0.0090293453724605 0.849989739380259 0.695895882712362 0.817775952565939 GO:0005200 structural constituent of cytoskeleton 1/198 112/18639 0.00892857142857143 0.840503246753247 0.6987223472723 0.818784497085286 GO:0046873 metal ion transmembrane transporter activity 4/198 450/18639 0.00888888888888889 0.836767676767677 0.707539835381016 0.823337172494741 GO:0101005 deubiquitinase activity 1/198 115/18639 0.00869565217391304 0.818577075098814 0.708279352772416 0.823337172494741 GO:0009055 electron transfer activity 1/198 116/18639 0.00862068965517241 0.811520376175549 0.711397506958935 0.823337172494741 GO:0015294 solute:monoatomic cation symporter activity 1/198 116/18639 0.00862068965517241 0.811520376175549 0.711397506958935 0.823337172494741 GO:0005125 cytokine activity 2/198 234/18639 0.00854700854700855 0.804584304584305 0.713342021947137 0.823337172494741 GO:1990782 protein tyrosine kinase binding 1/198 117/18639 0.00854700854700855 0.804584304584305 0.714482498246638 0.823337172494741 GO:0003697 single-stranded DNA binding 1/198 121/18639 0.00826446280991736 0.777986476333584 0.726497797822057 0.833625331714322 GO:0008528 G protein-coupled peptide receptor activity 1/198 122/18639 0.00819672131147541 0.771609538002981 0.729422165250032 0.833625331714322 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/198 122/18639 0.00819672131147541 0.771609538002981 0.729422165250032 0.833625331714322 GO:0005267 potassium channel activity 1/198 124/18639 0.00806451612903226 0.7591642228739 0.735177893524239 0.837901380016667 GO:0033218 amide binding 2/198 247/18639 0.00809716599190283 0.762237762237762 0.740887932157716 0.839112952902343 GO:0004519 endonuclease activity 1/198 127/18639 0.0078740157480315 0.741231209735147 0.743583857679211 0.839112952902343 GO:0019783 ubiquitin-like protein peptidase activity 1/198 127/18639 0.0078740157480315 0.741231209735147 0.743583857679211 0.839112952902343 GO:0001653 peptide receptor activity 1/198 128/18639 0.0078125 0.735440340909091 0.746326424456411 0.839112952902343 GO:0031490 chromatin DNA binding 1/198 128/18639 0.0078125 0.735440340909091 0.746326424456411 0.839112952902343 GO:0005179 hormone activity 1/198 132/18639 0.00757575757575758 0.713154269972452 0.757007893167756 0.846546461176846 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/198 132/18639 0.00757575757575758 0.713154269972452 0.757007893167756 0.846546461176846 GO:0061659 ubiquitin-like protein ligase activity 3/198 372/18639 0.00806451612903226 0.7591642228739 0.759239092890718 0.846765315395546 GO:0030695 GTPase regulator activity 4/198 489/18639 0.0081799591002045 0.770031604387433 0.766517435236716 0.851857233741989 GO:0060589 nucleoside-triphosphatase regulator activity 4/198 490/18639 0.00816326530612245 0.768460111317254 0.767900150608764 0.851857233741989 GO:0022843 voltage-gated monoatomic cation channel activity 1/198 143/18639 0.00699300699300699 0.65829624920534 0.784129747036807 0.867547805232212 GO:0019955 cytokine binding 1/198 144/18639 0.00694444444444444 0.653724747474748 0.786440641829557 0.867796570294684 GO:0015293 symporter activity 1/198 146/18639 0.00684931506849315 0.644769613947696 0.790988848603053 0.870506246081667 GO:0008017 microtubule binding 2/198 276/18639 0.0072463768115942 0.682147562582345 0.794297496234383 0.871841051275735 GO:0004175 endopeptidase activity 3/198 405/18639 0.00740740740740741 0.697306397306397 0.807617091015761 0.882412203260349 GO:0005506 iron ion binding 1/198 154/18639 0.00649350649350649 0.611275088547816 0.808237937326775 0.882412203260349 GO:0004386 helicase activity 1/198 155/18639 0.00645161290322581 0.60733137829912 0.810291975109263 0.882412203260349 GO:0099106 ion channel regulator activity 1/198 160/18639 0.00625 0.588352272727273 0.820238395467664 0.890911677583677 GO:0016887 ATP hydrolysis activity 3/198 417/18639 0.00719424460431655 0.67724002616089 0.823070528653533 0.891659739374661 GO:0001664 G protein-coupled receptor binding 2/198 297/18639 0.00673400673400673 0.633914906642179 0.826693742340436 0.893258693022393 GO:0016247 channel regulator activity 1/198 168/18639 0.00595238095238095 0.560335497835498 0.835084425474686 0.899987360097071 GO:0141108 transporter regulator activity 1/198 170/18639 0.00588235294117647 0.553743315508021 0.838601197137874 0.901442113719265 GO:0005244 voltage-gated monoatomic ion channel activity 1/198 173/18639 0.00578034682080925 0.544140830267998 0.843736929585803 0.902832694882737 GO:0003823 antigen binding 1/198 174/18639 0.00574712643678161 0.541013584117032 0.845412446099505 0.902832694882737 GO:0022832 voltage-gated channel activity 1/198 175/18639 0.00571428571428571 0.537922077922078 0.847070086807455 0.902832694882737 GO:0004252 serine-type endopeptidase activity 1/198 176/18639 0.00568181818181818 0.534865702479339 0.848710041465824 0.902832694882737 GO:0051020 GTPase binding 2/198 315/18639 0.00634920634920635 0.597691197691198 0.850746193254887 0.902832694882737 GO:0004842 ubiquitin-protein transferase activity 3/198 449/18639 0.0066815144766147 0.628973476412229 0.85921141770677 0.909496055384266 GO:0015078 proton transmembrane transporter activity 1/198 185/18639 0.00540540540540541 0.508845208845209 0.862704095355956 0.910875390020502 GO:0008234 cysteine-type peptidase activity 1/198 187/18639 0.0053475935828877 0.503403014098201 0.865634569063239 0.910973656188713 GO:0022804 active transmembrane transporter activity 3/198 457/18639 0.00656455142231947 0.617962999801074 0.867176845795024 0.910973656188713 GO:0008236 serine-type peptidase activity 1/198 194/18639 0.00515463917525773 0.485238987816307 0.875409654946202 0.917305834905843 GO:0017171 serine hydrolase activity 1/198 198/18639 0.00505050505050505 0.475436179981635 0.880674268495629 0.920503758025583 GO:0061630 ubiquitin protein ligase activity 2/198 353/18639 0.0056657223796034 0.533350502189029 0.891862101357239 0.925772410673379 GO:0004518 nuclease activity 1/198 209/18639 0.00478468899521531 0.450413223140496 0.894038100493684 0.925772410673379 GO:0051015 actin filament binding 1/198 209/18639 0.00478468899521531 0.450413223140496 0.894038100493684 0.925772410673379 GO:0045182 translation regulator activity 2/198 356/18639 0.00561797752808989 0.528855975485189 0.894616608391102 0.925772410673379 GO:0005543 phospholipid binding 3/198 497/18639 0.00603621730382294 0.568227547100786 0.901345294823167 0.930420949494883 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 1/198 229/18639 0.00436681222707424 0.411075823739579 0.914634848315696 0.940419822926427 GO:0000287 magnesium ion binding 1/198 230/18639 0.00434782608695652 0.409288537549407 0.915552952608661 0.940419822926427 GO:0042393 histone binding 1/198 247/18639 0.00404858299595142 0.381118881118881 0.929739585484712 0.952639575274976 GO:0003713 transcription coactivator activity 1/198 256/18639 0.00390625 0.367720170454545 0.936262570780134 0.95696616571139 GO:0016757 glycosyltransferase activity 1/198 267/18639 0.00374531835205993 0.352570650323459 0.94342214350268 0.959663509777352 GO:0008514 organic anion transmembrane transporter activity 1/198 269/18639 0.00371747211895911 0.349949307198378 0.944635114487569 0.959663509777352 GO:0005096 GTPase activator activity 1/198 271/18639 0.003690036900369 0.347366655484737 0.945822209155564 0.959663509777352 GO:0031267 small GTPase binding 1/198 283/18639 0.00353356890459364 0.332637327336974 0.952431335444349 0.963717470587232 GO:0015291 secondary active transmembrane transporter activity 1/198 287/18639 0.00348432055749129 0.328001267025657 0.95445095644697 0.963717470587232 GO:0022836 gated channel activity 1/198 318/18639 0.00314465408805031 0.296026300743282 0.967467610961574 0.974495220726429 GO:0005261 monoatomic cation channel activity 1/198 341/18639 0.00293255131964809 0.276059717408691 0.97466555220947 0.979374081447197 GO:0140098 catalytic activity, acting on RNA 1/198 387/18639 0.00258397932816537 0.243246417665022 0.984650648091935 0.987023300256012 GO:0005216 monoatomic ion channel activity 1/198 448/18639 0.00223214285714286 0.210125811688312 0.992117697621215 0.992117697621215