category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Human Diseases Infectious disease: bacterial hsa05110 Vibrio cholerae infection 1/2 51/9376 91.921568627451 PLCG2 9.50967662435732 Environmental Information Processing Signal transduction hsa04370 VEGF signaling pathway 1/2 60/9376 78.1333333333333 PLCG2 8.75469754116646 Organismal Systems Immune system hsa04664 Fc epsilon RI signaling pathway 1/2 69/9376 67.9420289855072 PLCG2 8.15186016649216 Human Diseases Infectious disease: bacterial hsa05120 Epithelial cell signaling in Helicobacter pylori infection 1/2 71/9376 66.0281690140845 PLCG2 8.03360867314194 Human Diseases Cancer: specific types hsa05223 Non-small cell lung cancer 1/2 73/9376 64.2191780821918 PLCG2 7.92021418432805 Human Diseases Cancer: specific types hsa05214 Glioma 1/2 76/9376 61.6842105263158 PLCG2 7.75852546027068 Metabolism Carbohydrate metabolism hsa00562 Inositol phosphate metabolism 1/2 78/9376 60.1025641025641 PLCG2 7.65591344043598 Human Diseases Drug resistance: antineoplastic hsa01521 EGFR tyrosine kinase inhibitor resistance 1/2 80/9376 58.6 PLCG2 7.55714196647281 Environmental Information Processing Signal transduction hsa04012 ErbB signaling pathway 1/2 86/9376 54.5116279069767 PLCG2 7.28161467056251 Organismal Systems Immune system hsa04662 B cell receptor signaling pathway 1/2 91/9376 51.5164835164835 PLCG2 7.07295695426676 Environmental Information Processing Signal transduction hsa04070 Phosphatidylinositol signaling system 1/2 98/9376 47.8367346938775 PLCG2 6.80786013958895 Organismal Systems Immune system hsa04666 Fc gamma R-mediated phagocytosis 1/2 98/9376 47.8367346938775 PLCG2 6.80786013958895 Organismal Systems Sensory system hsa04750 Inflammatory mediator regulation of TRP channels 1/2 99/9376 47.3535353535354 PLCG2 6.77227903035127 Human Diseases Endocrine and metabolic disease hsa04933 AGE-RAGE signaling pathway in diabetic complications 1/2 101/9376 46.4158415841584 PLCG2 6.70269188036625 Environmental Information Processing Signal transduction hsa04064 NF-kappa B signaling pathway 1/2 105/9376 44.6476190476191 PLCG2 6.56946614078627 Organismal Systems Immune system hsa04625 C-type lectin receptor signaling pathway 1/2 105/9376 44.6476190476191 PLCG2 6.56946614078627 Environmental Information Processing Signal transduction hsa04066 HIF-1 signaling pathway 1/2 110/9376 42.6181818181818 PLCG2 6.41315090556051 Organismal Systems Immune system hsa04670 Leukocyte transendothelial migration 1/2 116/9376 40.4137931034483 PLCG2 6.23892687230293 Organismal Systems Nervous system hsa04722 Neurotrophin signaling pathway 1/2 120/9376 39.0666666666667 PLCG2 6.13002097700562 Organismal Systems Endocrine system hsa04919 Thyroid hormone signaling pathway 1/2 122/9376 38.4262295081967 PLCG2 6.07756210774511 Organismal Systems Endocrine system hsa04935 Growth hormone synthesis, secretion and action 1/2 122/9376 38.4262295081967 PLCG2 6.07756210774511 Organismal Systems Immune system hsa04611 Platelet activation 1/2 126/9376 37.2063492063492 PLCG2 5.97636761145722 Organismal Systems Immune system hsa04650 Natural killer cell mediated cytotoxicity 1/2 133/9376 35.2481203007519 PLCG2 5.81024232588939 Metabolism Energy metabolism hsa00190 Oxidative phosphorylation 1/2 138/9376 33.9710144927536 MT-ND3 5.69929367405128 Organismal Systems Development and regeneration hsa04380 Osteoclast differentiation 1/2 142/9376 33.0140845070423 PLCG2 5.61472494105974 Environmental Information Processing Signal transduction hsa04072 Phospholipase D signaling pathway 1/2 149/9376 31.4630872483221 PLCG2 5.47488434978438 Organismal Systems Nervous system hsa04723 Retrograde endocannabinoid signaling 1/2 149/9376 31.4630872483221 MT-ND3 5.47488434978438 Human Diseases Cancer: specific types hsa05225 Hepatocellular carcinoma 1/2 170/9376 27.5764705882353 PLCG2 5.1076889557771 Organismal Systems Development and regeneration hsa04360 Axon guidance 1/2 184/9376 25.4782608695652 PLCG2 4.89804334346912 Organismal Systems Immune system hsa04062 Chemokine signaling pathway 1/2 193/9376 24.2901554404145 PLCG2 4.77525876985669 Organismal Systems Immune system hsa04613 Neutrophil extracellular trap formation 1/2 195/9376 24.0410256410256 PLCG2 4.74911056564063 Human Diseases Infectious disease: viral hsa05167 Kaposi sarcoma-associated herpesvirus infection 1/2 196/9376 23.9183673469388 PLCG2 4.73618363396592 Human Diseases Cancer: overview hsa05205 Proteoglycans in cancer 1/2 204/9376 22.9803921568627 PLCG2 4.63614124373985 Human Diseases Infectious disease: viral hsa05169 Epstein-Barr virus infection 1/2 205/9376 22.8682926829268 PLCG2 4.6240404342576 Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 1/2 205/9376 22.8682926829268 MT-ND3 4.6240404342576 Human Diseases Infectious disease: viral hsa05170 Human immunodeficiency virus 1 infection 1/2 214/9376 21.9065420560748 PLCG2 4.51889354872814 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 1/2 227/9376 20.6519823788546 MT-ND3 4.37794843799307 Organismal Systems Environmental adaptation hsa04714 Thermogenesis 1/2 235/9376 19.9489361702128 MT-ND3 4.2969477319872 Environmental Information Processing Signal transduction hsa04014 Ras signaling pathway 1/2 238/9376 19.6974789915966 PLCG2 4.26760403453002 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 1/2 238/9376 19.6974789915966 PLCG2 4.26760403453002 Human Diseases Infectious disease: bacterial hsa05131 Shigellosis 1/2 253/9376 18.5296442687747 PLCG2 4.1285988531196 Environmental Information Processing Signal transduction hsa04020 Calcium signaling pathway 1/2 254/9376 18.4566929133858 PLCG2 4.11976039241378 Human Diseases Neurodegenerative disease hsa05012 Parkinson disease 1/2 268/9376 17.4925373134328 MT-ND3 4.00111950288186 Human Diseases Neurodegenerative disease hsa05020 Prion disease 1/2 275/9376 17.0472727272727 MT-ND3 3.94512878389589 NA NA hsa04517 IgSF CAM signaling 1/2 299/9376 15.6789297658863 PLCG2 3.76787928453354 Human Diseases Neurodegenerative disease hsa05016 Huntington disease 1/2 308/9376 15.2207792207792 MT-ND3 3.70664640005363 Human Diseases Cancer: overview hsa05206 MicroRNAs in cancer 1/2 323/9376 14.5139318885449 PLCG2 3.61014701677006 Human Diseases Neurodegenerative disease hsa05014 Amyotrophic lateral sclerosis 1/2 368/9376 12.7391304347826 MT-ND3 3.35570527162815 Human Diseases Neurodegenerative disease hsa05010 Alzheimer disease 1/2 388/9376 12.0824742268041 MT-ND3 3.25656103608023 Human Diseases Neurodegenerative disease hsa05022 Pathways of neurodegeneration - multiple diseases 1/2 480/9376 9.76666666666667 MT-ND3 2.88002254049891