category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	5/25	238/9376	7.87899159663866	FGF10/PLCG2/PDGFD/IGF2/RASAL2	5.55794563766946
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	5/25	362/9376	5.18011049723757	VTN/FGF10/PDGFD/IGF2/LAMB1	4.1938209467659
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	2/25	42/9376	17.8590476190476	CYP1A2/INMT	5.66174621338908
NA	NA	hsa04518	Integrin signaling	3/25	154/9376	7.30597402597403	VTN/PDGFD/LAMB1	4.07968463724218
Human Diseases	Cancer: specific types	hsa05218	Melanoma	2/25	73/9376	10.2750684931507	FGF10/PDGFD	4.11333100390797
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	3/25	203/9376	5.54246305418719	VTN/PDGFD/LAMB1	3.3830649829552
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	3/25	204/9376	5.51529411764706	VTN/PLCG2/IGF2	3.37128694971057
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	2/25	80/9376	9.376	PLCG2/PDGFD	3.890095101411
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	2/25	88/9376	8.52363636363636	VTN/CFD	3.66635609531396
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	2/25	89/9376	8.42786516853933	VTN/LAMB1	3.640389946806
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	3/25	254/9376	4.4296062992126	FGF10/PLCG2/PDGFD	2.86511927633405
NA	NA	hsa04517	IgSF CAM signaling	3/25	299/9376	3.76294314381271	PLCG2/CADM3/NFASC	2.51051597085727
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	3/25	300/9376	3.7504	FGF10/PDGFD/IGF2	2.5034323334938
Metabolism	Metabolism of other amino acids	hsa00450	Selenocompound metabolism	1/25	17/9376	22.0611764705882	INMT	4.49385420248294
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	2/25	149/9376	5.03409395973154	PLCG2/PDGFD	2.56646589404143
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	2/25	160/9376	4.688	CADM3/NFASC	2.43279931418913
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	2/25	170/9376	4.41223529411765	PLCG2/IGF2	2.32142448168989
Metabolism	Lipid metabolism	hsa00591	Linoleic acid metabolism	1/25	30/9376	12.5013333333333	CYP1A2	3.26228983934196
Metabolism	Carbohydrate metabolism	hsa00030	Pentose phosphate pathway	1/25	31/9376	12.098064516129	FBP1	3.20011107817063
Metabolism	Carbohydrate metabolism	hsa00051	Fructose and mannose metabolism	1/25	35/9376	10.7154285714286	FBP1	2.977322732241
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	1/25	38/9376	9.86947368421053	NNMT	2.83262658656747
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	2/25	212/9376	3.53811320754717	FGF10/PDGFD	1.93269353222188
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	2/25	217/9376	3.45658986175115	FGF10/CYP1A2	1.89306317169127
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	1/25	45/9376	8.33422222222222	ABCA8	2.54989819124068
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	2/25	227/9376	3.30431718061674	MT-ATP8/CYP1A2	1.8171676081361
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	2/25	232/9376	3.23310344827586	FGF10/PDGFD	1.78078438960292
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	1/25	51/9376	7.35372549019608	PLCG2	2.35242469180481
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	2/25	238/9376	3.15159663865546	PLCG2/CFD	1.73840263995711
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/25	60/9376	6.25066666666667	PLCG2	2.10960889378939
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/25	61/9376	6.14819672131148	MT1E	2.08571630197997
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	1/25	66/9376	5.68242424242424	CYP1A2	1.97376071602554
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	1/25	67/9376	5.59761194029851	FBP1	1.95274175266515
Metabolism	Metabolism of cofactors and vitamins	hsa00830	Retinol metabolism	1/25	68/9376	5.51529411764706	CYP1A2	1.9321414957916
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	1/25	69/9376	5.43536231884058	PLCG2	1.91194504413296
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	1/25	70/9376	5.35771428571429	CYP1A2	1.89213823708303
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	1/25	71/9376	5.28225352112676	PLCG2	1.87270760784116
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	1/25	73/9376	5.13753424657534	CYP1A2	1.83492422818627
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	1/25	73/9376	5.13753424657534	PLCG2	1.83492422818627
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	1/25	75/9376	5.00053333333333	AIFM2	1.79849948148207
Human Diseases	Cancer: specific types	hsa05214	Glioma	1/25	76/9376	4.93473684210526	PLCG2	1.7807691676559
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	1/25	78/9376	4.80820512820513	PLCG2	1.74622209068708
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	1/25	79/9376	4.7473417721519	CYP1A2	1.72938643629863
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	2/25	308/9376	2.43532467532468	DNAH10/MT-ATP8	1.32433045866693
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/25	86/9376	4.36093023255814	PLCG2	1.6189277970415
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	1/25	89/9376	4.21393258426966	PDGFD	1.5751454292739
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/25	91/9376	4.12131868131868	PLCG2	1.54701479744572
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/25	93/9376	4.03268817204301	CST3	1.51967832961624
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/25	93/9376	4.03268817204301	LAMB1	1.51967832961624
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	2/25	333/9376	2.25249249249249	VTN/LAMB1	1.20328248938649
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/25	98/9376	3.8269387755102	PLCG2	1.45455072335108
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	1/25	98/9376	3.8269387755102	PLCG2	1.45455072335108
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/25	99/9376	3.78828282828283	PLCG2	1.44203983382665
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	1/25	99/9376	3.78828282828283	CFD	1.44203983382665
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	1/25	99/9376	3.78828282828283	PDGFD	1.44203983382665
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	1/25	101/9376	3.71326732673267	PLCG2	1.41749954071897
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	1/25	103/9376	3.64116504854369	LAMB1	1.39357593456432
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	1/25	105/9376	3.57180952380952	PLCG2	1.37024041648173
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/25	105/9376	3.57180952380952	PLCG2	1.37024041648173
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/25	106/9376	3.53811320754717	PDGFD	1.35878476444179
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/25	107/9376	3.50504672897196	FBP1	1.3474662411965
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	1/25	110/9376	3.40945454545455	PLCG2	1.31430314280654
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	1/25	110/9376	3.40945454545455	FST	1.31430314280654
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	2/25	368/9376	2.03826086956522	DNAH10/MT-ATP8	1.05061312269364
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	1/25	112/9376	3.34857142857143	LAMB1	1.29282614218625
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	1/25	116/9376	3.23310344827586	FBP1	1.25129283420436
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/25	116/9376	3.23310344827586	PLCG2	1.25129283420436
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	1/25	120/9376	3.12533333333333	PLCG2	1.21152566242872
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/25	122/9376	3.07409836065574	FBP1	1.19226042905789
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/25	122/9376	3.07409836065574	PLCG2	1.19226042905789
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	1/25	122/9376	3.07409836065574	PLCG2	1.19226042905789
Organismal Systems	Immune system	hsa04611	Platelet activation	1/25	126/9376	2.97650793650794	PLCG2	1.15488723946624
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	1/25	133/9376	2.81984962406015	PLCG2	1.09290260541774
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	1/25	138/9376	2.71768115942029	MT-ATP8	1.05104117576241
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	1/25	138/9376	2.71768115942029	FBP1	1.05104117576241
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	1/25	142/9376	2.64112676056338	PLCG2	1.018868131298
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	1/25	148/9376	2.53405405405405	FGF10	0.972622566070821
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	1/25	150/9376	2.50026666666667	FGF10	0.957709903784772
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	1/25	158/9376	2.37367088607595	CDKN1C	0.900366855789544
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	2/25	480/9376	1.56266666666667	DNAH10/MT-ATP8	0.65433632902274
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	1/25	174/9376	2.15540229885057	HSPBP1	0.795414220379465
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/25	184/9376	2.03826086956522	PLCG2	0.735422654629876
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	1/25	193/9376	1.94321243523316	PLCG2	0.684577300006303
Cellular Processes	Cell motility	hsa04814	Motor proteins	1/25	194/9376	1.93319587628866	DNAH10	0.679096740251159
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	1/25	195/9376	1.92328205128205	PLCG2	0.673648456324017
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	1/25	196/9376	1.9134693877551	PLCG2	0.668232058222787
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	1/25	205/9376	1.82946341463415	PLCG2	0.620858216629675
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	1/25	205/9376	1.82946341463415	MT-ATP8	0.620858216629675
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	1/25	214/9376	1.75252336448598	PLCG2	0.575782346839726
NA	NA	hsa04081	Hormone signaling	1/25	219/9376	1.71251141552511	IGF2	0.55165034124409
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	1/25	233/9376	1.60961373390558	FBN2	0.487208613008181
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	1/25	235/9376	1.59591489361702	MT-ATP8	0.478352370555937
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	1/25	253/9376	1.48237154150198	PLCG2	0.402160780410524
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	1/25	268/9376	1.39940298507463	MT-ATP8	0.342999752348792
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	1/25	275/9376	1.36378181818182	MT-ATP8	0.316584314143466
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	1/25	298/9376	1.25852348993289	IL1RL1	0.234498282870762
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	1/25	323/9376	1.16111455108359	PLCG2	0.15235839204716
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	1/25	388/9376	0.96659793814433	MT-ATP8	-0.0347443523700559