category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	19/60	233/9376	12.7427753934192	ACTB/COL4A2/SYNE2/FN1/COL4A1/COL6A1/NID1/FBLN1/LMOD1/TPM1/COL11A1/SYNPO2/ITGB1/TPM4/DSP/COL6A2/MYL9/FHL1/ACTG1	14.5663546031682
NA	NA	hsa04518	Integrin signaling	14/60	154/9376	14.2060606060606	ACTB/COL4A2/FN1/COL4A1/COL6A1/LAMC1/ARHGEF6/ITGB1/COL6A2/FLNA/PDGFRB/PDGFD/ACTG1/ACTN4	13.2607354483452
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	15/60	203/9376	11.5467980295567	ACTB/COL4A2/FN1/COL4A1/COL6A1/LAMC1/ITGB1/COL6A2/MYL9/FLNA/PDGFRB/PDGFD/ACTG1/ACTN4/BCL2	12.1915654653311
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	13/60	362/9376	5.61178637200737	COL4A2/FN1/COL4A1/COL6A1/LAMC1/ITGB1/PRLR/COL6A2/PDGFRB/PDGFD/CREB3L1/FGF10/BCL2	7.18143466104969
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	7/60	89/9376	12.2906367041199	COL4A2/FN1/COL4A1/COL6A1/LAMC1/ITGB1/COL6A2	8.58859724717022
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	10/60	232/9376	6.73563218390805	ACTB/FN1/ARHGEF6/ITGB1/MYL9/PDGFRB/PDGFD/ACTG1/ACTN4/FGF10	7.09910664314152
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	7/60	99/9376	11.0491582491582	ACTB/SLC8A1/TPM1/ITGB1/TPM4/TGFB2/ACTG1	8.06659081994014
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	7/60	101/9376	10.8303630363036	PLCG2/COL4A2/FN1/COL4A1/F3/TGFB2/BCL2	7.97112845535533
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	7/60	105/9376	10.4177777777778	ACTB/SLC8A1/TPM1/ITGB1/TPM4/TGFB2/ACTG1	7.78800678224067
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	6/60	93/9376	10.0817204301075	COL4A2/FN1/COL4A1/LAMC1/ITGB1/BCL2	7.06336991188428
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	8/60	204/9376	6.1281045751634	PLCG2/ACTB/FN1/GPC3/ITGB1/TGFB2/FLNA/ACTG1	5.94273626715996
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	10/60	333/9376	4.69269269269269	COL4A2/FN1/COL4A1/COL6A1/LAMC1/ITGB1/COL6A2/PDGFRB/CREB3L1/JAG1	5.50624513189344
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	6/60	103/9376	9.10291262135922	COL4A2/COL4A1/COL6A1/SLC8A1/COL11A1/COL6A2	6.63584390548114
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	6/60	103/9376	9.10291262135922	COL4A2/FN1/COL4A1/LAMC1/TGFB2/ACTN4	6.63584390548114
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	6/60	116/9376	8.08275862068965	PLCG2/ACTB/ITGB1/MYL9/ACTG1/ACTN4	6.1598830394894
NA	NA	hsa04517	IgSF CAM signaling	9/60	299/9376	4.70367892976589	PLCG2/ACTB/NFASC/CADM3/NRP1/ITGB1/MYL9/ACTG1/ACTN4	5.22329170749511
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	5/60	86/9376	9.08527131782946	ACTB/SLC8A1/ITGB1/DSP/ACTG1	6.04480771054083
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	4/60	51/9376	12.2562091503268	PLCG2/ACTB/CFTR/ACTG1	6.4684368912169
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	6/60	170/9376	5.51529411764706	ACTB/CFTR/ITGB1/MYL9/ACTG1/ACTN4	4.76783858059061
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	7/60	253/9376	4.3235836627141	PLCG2/ACTB/ITGB1/MYL9/ACTG1/ACTN4/BCL2	4.30075360567167
Cellular Processes	Cell motility	hsa04814	Motor proteins	6/60	194/9376	4.83298969072165	ACTB/TPM1/ACTA2/TPM4/MYL9/ACTG1	4.32928718014464
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	4/60	78/9376	8.01367521367521	ACTB/FN1/ITGB1/ACTG1	4.99165664902417
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	4/60	80/9376	7.81333333333333	PLCG2/PDGFRB/PDGFD/BCL2	4.9113750105653
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	6/60	212/9376	4.42264150943396	ACTB/ITGB1/PDGFRB/PDGFD/ACTG1/FGF10	4.04513785674195
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	4/60	93/9376	6.72114695340502	ACTB/MYL9/ACTG1/ACTN4	4.44966100455825
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	5/60	154/9376	5.07359307359307	SLC8A1/TPM1/TPM4/CREB3L1/BCL2	4.09045828915387
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	6/60	235/9376	3.98978723404255	ACTB/MT-ND3/MT-ATP8/CREB3L1/ACTG1/MT-ND4L	3.7249794683388
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	5/60	168/9376	4.65079365079365	IL6ST/PRLR/PDGFRB/FHL1/BCL2	3.83182613825655
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	4/60	106/9376	5.89685534591195	PDGFRB/PDGFD/CREB3L1/BCL2	4.06889857224686
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	6/60	248/9376	3.78064516129032	ACTB/MYL9/AHNAK/FLNA/ACTG1/BCL2	3.56147680433947
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	4/60	112/9376	5.58095238095238	LAMC1/ITGB1/TGFB2/BCL2	3.91392085088934
Organismal Systems	Immune system	hsa04611	Platelet activation	4/60	126/9376	4.96084656084656	PLCG2/ACTB/ITGB1/ACTG1	3.59210438224017
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	7/60	368/9376	2.97246376811594	ACTB/GPX3/MT-ND3/MT-ATP8/ACTG1/BCL2/MT-ND4L	3.09788490520625
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	4/60	130/9376	4.80820512820513	COL4A2/COL4A1/ACTA2/CREB3L1	3.50882403002783
Human Diseases	Cancer: specific types	hsa05218	Melanoma	3/60	73/9376	6.42191780821918	PDGFRB/PDGFD/FGF10	3.73206649271503
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	4/60	138/9376	4.52946859903382	ACTB/FN1/ITGB1/ACTG1	3.35201852517264
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	3/60	76/9376	6.16842105263158	ACTB/CFTR/ACTG1	3.63052751187549
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	6/60	323/9376	2.90278637770898	PLCG2/TPM1/TGFB2/PDGFRB/MARCKS/BCL2	2.79281107505716
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	5/60	238/9376	3.28291316526611	PLCG2/PLA2G2A/PDGFRB/PDGFD/FGF10	2.86285147756117
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	3/60	87/9376	5.38850574712644	SLC8A1/TPM1/TPM4	3.30018540853546
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	5/60	254/9376	3.0761154855643	PLCG2/SLC8A1/PDGFRB/PDGFD/FGF10	2.6919677682313
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	4/60	170/9376	3.67686274509804	PLCG2/ACTB/TGFB2/ACTG1	2.82658208712102
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	4/60	184/9376	3.39710144927536	PLCG2/NRP1/ITGB1/MYL9	2.63534113881848
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	5/60	275/9376	2.84121212121212	LAMC1/MT-ND3/MT-ATP8/CREB3L1/MT-ND4L	2.48697911678019
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	2/60	45/9376	6.94518518518518	ABCA8/CFTR	3.20814561662711
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	2/60	50/9376	6.25066666666667	TGFB2/HBA1	2.98743364976374
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	4/60	205/9376	3.04910569105691	MT-ND3/MT-ATP8/TGFB2/MT-ND4L	2.38056183516417
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	5/60	300/9376	2.60444444444444	TGFB2/FLNA/PDGFRB/PDGFD/FGF10	2.26665065957075
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	3/60	122/9376	3.84262295081967	PLCG2/ACTB/ACTG1	2.53618511512611
NA	NA	hsa04519	Cadherin signaling	6/60	404/9376	2.32079207920792	ACTB/DSP/LIMA1/PDGFRB/ACTG1/ACTN4	2.17784531155866
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	5/60	308/9376	2.53679653679654	GPX3/MT-ND3/MT-ATP8/CREB3L1/MT-ND4L	2.20080973862034
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	4/60	217/9376	2.88049155145929	CREB3L1/JAG1/FGF10/BCL2	2.24917758878926
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	3/60	134/9376	3.49850746268657	PLA2G2A/ACTA2/MYL9	2.33774206480064
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	3/60	137/9376	3.42189781021898	ACTB/ACTG1/BCL2	2.2916597553556
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	3/60	138/9376	3.39710144927536	MT-ND3/MT-ATP8/MT-ND4L	2.27658307170909
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	3/60	140/9376	3.34857142857143	SLC8A1/ACTA2/JAG1	2.24684106287468
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	3/60	142/9376	3.30140845070422	ACTB/ACTG1/BCL2	2.21763191962465
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	3/60	149/9376	3.14630872483221	PLCG2/PDGFRB/PDGFD	2.11934465239564
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	3/60	150/9376	3.12533333333333	TGFB2/FGF10/BCL2	2.10577750258849
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	2/60	70/9376	4.4647619047619	ACTB/ACTG1	2.33500285023411
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	3/60	154/9376	3.04415584415584	ACTB/MYL9/ACTG1	2.05261892044469
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	3/60	155/9376	3.02451612903226	ACTB/ITGB1/ACTG1	2.0395981182641
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	3/60	157/9376	2.9859872611465	ACTB/TGFB2/ACTG1	2.01386753407464
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	3/60	160/9376	2.93	NFASC/CADM3/ITGB1	1.97602570944568
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	2/60	75/9376	4.16711111111111	GPX3/CREB3L1	2.20991532130165
Human Diseases	Cancer: specific types	hsa05214	Glioma	2/60	76/9376	4.11228070175439	PLCG2/PDGFRB	2.18620360015856
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	3/60	163/9376	2.8760736196319	TGFB2/CREB3L1/BCL2	1.93905294183083
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	2/60	77/9376	4.05887445887446	ARHGEF6/TGFB2	2.16289489405257
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	2/60	78/9376	4.00683760683761	ITGB1/TGFB2	2.13997661360797
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	3/60	166/9376	2.82409638554217	SLC8A1/MYL9/CREB3L1	1.90291125656738
Metabolism	Metabolism of other amino acids	hsa00450	Selenocompound metabolism	1/60	17/9376	9.1921568627451	INMT	2.71302952492322
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	2/60	87/9376	3.59233716475096	TGFB2/BCL2	1.94945472971459
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	2/60	88/9376	3.55151515151515	F3/A2M	1.92985601471712
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	3/60	181/9376	2.59005524861878	CD74/TGFB2/BCL2	1.73349326568878
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	2/60	89/9376	3.51161048689139	PDGFRB/PDGFD	1.91053981090438
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	4/60	298/9376	2.09753914988814	IL6ST/IL1RL1/PRLR/TGFB2	1.54518181028086
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	3/60	195/9376	2.40410256410256	PLCG2/ACTB/ACTG1	1.59007521402071
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	2/60	98/9376	3.1891156462585	PLCG2/MARCKS	1.74824011871856
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	2/60	99/9376	3.15690235690236	JAG1/BCL2	1.73137374497542
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	2/60	99/9376	3.15690235690236	PDGFRB/PDGFD	1.73137374497542
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	3/60	200/9376	2.344	ACTB/ITGB1/ACTG1	1.54182146502054
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	2/60	102/9376	3.0640522875817	PLA2G2A/CFTR	1.68203008127981
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	3/60	205/9376	2.28682926829268	IL6ST/CREB3L1/ACTN4	1.49498225388742
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	2/60	105/9376	2.97650793650794	PLCG2/BCL2	1.63446808556025
Metabolism	Lipid metabolism	hsa00592	alpha-Linolenic acid metabolism	1/60	26/9376	6.01025641025641	PLA2G2A	2.05299241282374
Organismal Systems	Digestive system	hsa04977	Vitamin digestion and absorption	1/60	26/9376	6.01025641025641	SLC19A3	2.05299241282374
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	2/60	110/9376	2.84121212121212	PLCG2/BCL2	1.55883641822528
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	2/60	110/9376	2.84121212121212	TGFB2/FST	1.55883641822528
NA	NA	hsa04382	Cornified envelope formation	3/60	217/9376	2.16036866359447	COL4A2/COL4A1/DSP	1.38786860853734
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	2/60	115/9376	2.71768115942029	CREB3L1/BCL2	1.48733587576913
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	2/60	115/9376	2.71768115942029	CREB3L1/BCL2	1.48733587576913
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	2/60	117/9376	2.67122507122507	ACTB/ACTG1	1.45979662238463
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	3/60	224/9376	2.09285714285714	NRP1/TGFB2/CREB3L1	1.32854393782362
Metabolism	Lipid metabolism	hsa00591	Linoleic acid metabolism	1/60	30/9376	5.20888888888889	PLA2G2A	1.85294156454214
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	3/60	226/9376	2.07433628318584	CFTR/MYL9/CREB3L1	1.31198974140814
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	2/60	119/9376	2.62633053221288	CREB3L1/JAG1	1.43282677225699
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	3/60	227/9376	2.06519823788546	MT-ND3/MT-ATP8/MT-ND4L	1.30377628620603
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	2/60	120/9376	2.60444444444444	PLCG2/BCL2	1.41954824562198
Metabolism	Carbohydrate metabolism	hsa00630	Glyoxylate and dicarboxylate metabolism	1/60	31/9376	5.04086021505376	ACSS1	1.80847098238384
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	2/60	122/9376	2.56174863387978	CFTR/CREB3L1	1.39339043810658
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	2/60	122/9376	2.56174863387978	PLCG2/CREB3L1	1.39339043810658
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	1/60	32/9376	4.88333333333333	ACSS1	1.76587422829162
Cellular Processes	Cell growth and death	hsa04215	Apoptosis - multiple species	1/60	32/9376	4.88333333333333	BCL2	1.76587422829162
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	5/60	480/9376	1.62777777777778	GPX3/MT-ND3/MT-ATP8/BCL2/MT-ND4L	1.13311944773417
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	3/60	238/9376	1.96974789915966	PLCG2/IL6ST/NRP1	1.21609715525359
Metabolism	Glycan biosynthesis and metabolism	hsa00512	Mucin type O-glycan biosynthesis	1/60	36/9376	4.34074074074074	GALNT15	1.61163655371695
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	1/60	37/9376	4.22342342342342	HBA1	1.57657470825025
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	2/60	139/9376	2.2484412470024	CREB3L1/BCL2	1.19002630278394
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	2/60	142/9376	2.20093896713615	PLCG2/TGFB2	1.15722204210523
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	1/60	42/9376	3.72063492063492	INMT	1.41810222528714
Organismal Systems	Digestive system	hsa04975	Fat digestion and absorption	1/60	43/9376	3.63410852713178	PLA2G2A	1.3893247822705
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	2/60	148/9376	2.11171171171171	JAG1/FGF10	1.09399608832536
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	3/60	268/9376	1.74925373134328	MT-ND3/MT-ATP8/MT-ND4L	0.998691431921422
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	1/60	44/9376	3.55151515151515	CREB3L1	1.36139342331956
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	2/60	149/9376	2.09753914988814	MT-ND3/MT-ND4L	1.08375076763112
Metabolism	Carbohydrate metabolism	hsa00620	Pyruvate metabolism	1/60	47/9376	3.32482269503546	ACSS1	1.28223534017996
Metabolism	Glycan biosynthesis and metabolism	hsa00514	Other types of O-glycan biosynthesis	1/60	49/9376	3.1891156462585	GALNT15	1.23294095836707
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	1/60	49/9376	3.1891156462585	CREB3L1	1.23294095836707
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	1/60	51/9376	3.0640522875817	PLA2G2A	1.18611797134264
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/60	53/9376	2.94842767295597	SLC8A1	1.14153939890264
Environmental Information Processing	Signal transduction	hsa04340	Hedgehog signaling pathway	1/60	56/9376	2.79047619047619	BCL2	1.07845277177339
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	2/60	173/9376	1.80655105973025	ACTB/ACTG1	0.85928400975016
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/60	59/9376	2.64858757062147	GPX3	1.01940439754506
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/60	60/9376	2.60444444444444	PLCG2	1.00053455558958
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	2/60	180/9376	1.7362962962963	CD74/BCL2	0.800453136340494
Organismal Systems	Digestive system	hsa04978	Mineral absorption	1/60	61/9376	2.56174863387978	SLC8A1	0.982044451117275
Environmental Information Processing	Signal transduction	hsa04330	Notch signaling pathway	1/60	62/9376	2.52043010752688	JAG1	0.963919380639145
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	1/60	63/9376	2.48042328042328	PLA2G2A	0.946145444551333
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	1/60	65/9376	2.40410256410256	CREB3L1	0.911599064637806
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	1/60	66/9376	2.36767676767677	TGFB2	0.894802359246788
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	1/60	67/9376	2.33233830845771	ACSS1	0.87830817474726
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	2/60	196/9376	1.59455782312925	PLCG2/IL6ST	0.675067680802177
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	1/60	69/9376	2.26473429951691	PLCG2	0.846185362677986
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/60	69/9376	2.26473429951691	CREB3L1	0.846185362677986
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	1/60	70/9376	2.23238095238095	TGFB2	0.830537022595639
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	1/60	71/9376	2.20093896713615	PRLR	0.815151713481756
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	1/60	71/9376	2.20093896713615	PLCG2	0.815151713481756
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	1/60	71/9376	2.20093896713615	PDGFRB	0.815151713481756
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	1/60	73/9376	2.14063926940639	PLCG2	0.785135767121623
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	2/60	205/9376	1.52455284552846	PLCG2/BCL2	0.609402672610666
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	1/60	75/9376	2.08355555555556	BCL2	0.756072628870813
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	1/60	75/9376	2.08355555555556	BCL2	0.756072628870813
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/60	77/9376	2.02943722943723	TGFB2	0.727903206631336
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	1/60	78/9376	2.0034188034188	PLCG2	0.714136595899875
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	1/60	78/9376	2.0034188034188	ITGB1	0.714136595899875
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	2/60	214/9376	1.46043613707165	PLCG2/BCL2	0.546798945132092
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	1/60	82/9376	1.90569105691057	CD74	0.661046781345274
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/60	86/9376	1.81705426356589	PLCG2	0.610855927795785
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/60	86/9376	1.81705426356589	CREB3L1	0.610855927795785
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/60	90/9376	1.7362962962963	CREB3L1	0.563256295366272
Organismal Systems	Digestive system	hsa04976	Bile secretion	1/60	90/9376	1.7362962962963	CFTR	0.563256295366272
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/60	91/9376	1.71721611721612	PLCG2	0.55172962764188
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	1/60	93/9376	1.68028673835125	JAG1	0.529097643569199
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	3/60	388/9376	1.20824742268041	MT-ND3/MT-ATP8/MT-ND4L	0.336209893872349
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	1/60	95/9376	1.64491228070175	TGFB2	0.507004234773061
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/60	98/9376	1.59455782312925	PLCG2	0.474817235475456
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/60	98/9376	1.59455782312925	CREB3L1	0.474817235475456
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/60	99/9376	1.57845117845118	PLCG2	0.464330329982482
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	1/60	100/9376	1.56266666666667	IL6ST	0.453959742554558
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/60	101/9376	1.54719471947195	CREB3L1	0.44370277912372
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	1/60	103/9376	1.51715210355987	TGFB2	0.423519392961054
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	1/60	104/9376	1.5025641025641	PLA2G2A	0.41358801569336
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/60	105/9376	1.48825396825397	PLCG2	0.403760346224167
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	1/60	107/9376	1.46043613707165	CREB3L1	0.384407075558838
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	1/60	109/9376	1.43363914373089	IL6ST	0.365442176751592
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	1/60	109/9376	1.43363914373089	CREB3L1	0.365442176751592
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	1/60	116/9376	1.34712643678161	ACSS1	0.301896247634826
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	1/60	125/9376	1.25013333333333	BCL2	0.225932527162343
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	1/60	133/9376	1.1749373433584	TGFB2	0.163060359080131
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	1/60	133/9376	1.1749373433584	PLCG2	0.163060359080131
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	1/60	133/9376	1.1749373433584	CREB3L1	0.163060359080131
Human Diseases	Infectious disease: viral	hsa05162	Measles	1/60	136/9376	1.14901960784314	BCL2	0.140482882010715
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	1/60	143/9376	1.09277389277389	ACTN4	0.089715793842362
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	1/60	144/9376	1.08518518518519	IL6ST	0.0826692396949984
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	1/60	155/9376	1.00817204301075	CREB3L1	0.00823292208349647
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	1/60	157/9376	0.995329087048832	TGFB2	-0.00473648554090672
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	1/60	158/9376	0.989029535864979	TGFB2	-0.0111604502796258
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/60	168/9376	0.93015873015873	BCL2	-0.0733045000362123
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	1/60	169/9376	0.92465483234714	BCL2	-0.0793206396547441
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	1/60	174/9376	0.898084291187739	BCL2	-0.108898315633419
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	1/60	187/9376	0.835650623885918	BCL2	-0.182180236180203
Human Diseases	Substance dependence	hsa05034	Alcoholism	1/60	191/9376	0.818150087260035	CREB3L1	-0.203768347635925
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	1/60	193/9376	0.809671848013817	PLCG2	-0.21440549741624
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	1/60	201/9376	0.777446102819237	PROM1	-0.255962721667268
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	1/60	216/9376	0.723456790123457	BCL2	-0.329980792825297
NA	NA	hsa04081	Hormone signaling	1/60	219/9376	0.713546423135464	PRLR	-0.344228023582754
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	1/60	227/9376	0.688399412628488	CREB3L1	-0.381391408785385
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	1/60	370/9376	0.422342342342342	PRLR	-0.909812604176169
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	1/60	449/9376	0.348032665181886	SLC8A1	-1.1361685502898