ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003779 actin binding 36/339 443/18639 0.0812641083521445 4.46808765656525 5.60689221249555e-14 4.09863820733425e-11 GO:0045296 cadherin binding 27/339 334/18639 0.0808383233532934 4.44467701764612 1.03099699020922e-10 3.76829399921471e-08 GO:0051015 actin filament binding 20/339 209/18639 0.0956937799043062 5.2614641995173 1.61900528164067e-09 3.94497620293111e-07 GO:0019838 growth factor binding 14/339 136/18639 0.102941176470588 5.65994273815721 1.90914808207723e-07 3.48896811999613e-05 GO:0005178 integrin binding 15/339 161/18639 0.093167701863354 5.12257461661078 2.60205093354769e-07 3.80419846484673e-05 GO:0019955 cytokine binding 14/339 144/18639 0.0972222222222222 5.34550147492625 3.8799780552708e-07 4.7220247517461e-05 GO:0005201 extracellular matrix structural constituent 15/339 168/18639 0.0892857142857143 4.90913400758533 4.52177472807424e-07 4.7220247517461e-05 GO:0004896 cytokine receptor activity 11/339 96/18639 0.114583333333333 6.30005530973451 1.36211293050943e-06 0.0001244630690253 GO:0050840 extracellular matrix binding 9/339 67/18639 0.134328358208955 7.38568220842689 3.31108902857644e-06 0.000268934008876598 GO:0002020 protease binding 12/339 136/18639 0.0882352941176471 4.85137948984904 7.27529925717562e-06 0.000531824375699538 GO:0098631 cell adhesion mediator activity 9/339 76/18639 0.118421052631579 6.51106194690265 9.55789171581056e-06 0.000635165349477956 GO:0008201 heparin binding 13/339 172/18639 0.0755813953488372 4.15563902037456 1.64445567050614e-05 0.00100174757928332 GO:0140375 immune receptor activity 12/339 156/18639 0.0769230769230769 4.22940776038121 2.91573114041867e-05 0.0016395380489585 GO:0005080 protein kinase C binding 7/339 52/18639 0.134615384615385 7.40146358066712 4.09838306328306e-05 0.00213994144232851 GO:1901681 sulfur compound binding 16/339 275/18639 0.0581818181818182 3.19897023330652 4.69441624742083e-05 0.00215086901866531 GO:0042805 actinin binding 6/339 37/18639 0.162162162162162 8.91604879215499 5.00202097364024e-05 0.00215086901866531 GO:0043394 proteoglycan binding 6/339 37/18639 0.162162162162162 8.91604879215499 5.00202097364024e-05 0.00215086901866531 GO:0098632 cell-cell adhesion mediator activity 7/339 55/18639 0.127272727272727 6.997747385358 5.9331328791232e-05 0.00240951118591059 GO:0051371 muscle alpha-actinin binding 4/339 15/18639 0.266666666666667 14.6619469026549 0.000125216977082751 0.00481755843407848 GO:0005539 glycosaminoglycan binding 14/339 242/18639 0.0578512396694215 3.18079426607182 0.000147339728423487 0.00538526707387846 GO:0001968 fibronectin binding 5/339 30/18639 0.166666666666667 9.16371681415929 0.000189440238909518 0.00659432450680274 GO:0005200 structural constituent of cytoskeleton 9/339 112/18639 0.0803571428571429 4.4182206068268 0.000208071655732181 0.00691365365182839 GO:0097110 scaffold protein binding 7/339 70/18639 0.1 5.49823008849558 0.000277707795542948 0.00882627819747371 GO:0005518 collagen binding 7/339 72/18639 0.0972222222222222 5.34550147492625 0.000330853631530826 0.0100772501937097 GO:0005158 insulin receptor binding 4/339 23/18639 0.173913043478261 9.56213928434013 0.000724126293727191 0.0211734528285831 GO:0001540 amyloid-beta binding 7/339 83/18639 0.0843373493975904 4.63706152041796 0.00078669001156996 0.0215116193667813 GO:0044325 transmembrane transporter binding 9/339 136/18639 0.0661764705882353 3.63853461738678 0.000867332441456501 0.0215116193667813 GO:0005114 type II transforming growth factor beta receptor binding 3/339 11/18639 0.272727272727273 14.9951729686243 0.000882829796174335 0.0215116193667813 GO:0048407 platelet-derived growth factor binding 3/339 11/18639 0.272727272727273 14.9951729686243 0.000882829796174335 0.0215116193667813 GO:0097493 structural molecule activity conferring elasticity 3/339 11/18639 0.272727272727273 14.9951729686243 0.000882829796174335 0.0215116193667813 GO:0061134 peptidase regulator activity 12/339 226/18639 0.0530973451327434 2.91941420628084 0.000924039324875848 0.0216133030234138 GO:0008307 structural constituent of muscle 5/339 42/18639 0.119047619047619 6.54551201011378 0.000946136384061891 0.0216133030234138 GO:0001223 transcription coactivator binding 5/339 44/18639 0.113636363636364 6.24798873692679 0.00117262523512135 0.025211442555109 GO:0030020 extracellular matrix structural constituent conferring tensile strength 5/339 44/18639 0.113636363636364 6.24798873692679 0.00117262523512135 0.025211442555109 GO:0023026 MHC class II protein complex binding 4/339 27/18639 0.148148148148148 8.14552605703048 0.00135531849687173 0.0283067948918068 GO:0005516 calmodulin binding 11/339 207/18639 0.0531400966183575 2.92176478132615 0.00148342941022603 0.0301218583020896 GO:0051393 alpha-actinin binding 4/339 28/18639 0.142857142857143 7.85461441213654 0.00155877126291798 0.030796264680893 GO:0005161 platelet-derived growth factor receptor binding 3/339 14/18639 0.214285714285714 11.7819216182048 0.0018702440367773 0.0359255105754872 GO:0033218 amide binding 12/339 247/18639 0.048582995951417 2.6712049012934 0.00196582821206496 0.0359255105754872 GO:0042393 histone binding 12/339 247/18639 0.048582995951417 2.6712049012934 0.00196582821206496 0.0359255105754872 GO:0042277 peptide binding 12/339 249/18639 0.0481927710843374 2.64974944023883 0.00210192478209395 0.0374757808709921 GO:0005159 insulin-like growth factor receptor binding 3/339 16/18639 0.1875 10.3091814159292 0.00280079251691477 0.0487471269015405 GO:0008083 growth factor activity 9/339 162/18639 0.0555555555555556 3.05457227138643 0.00290744058035406 0.0494264898660191 GO:0140297 DNA-binding transcription factor binding 18/339 488/18639 0.0368852459016393 2.02803568837952 0.00376276398521574 0.0617902837880695 GO:0030414 peptidase inhibitor activity 9/339 169/18639 0.0532544378698225 2.92805152641776 0.00384879118457361 0.0617902837880695 GO:0034185 apolipoprotein binding 3/339 18/18639 0.166666666666667 9.16371681415929 0.00397283630374729 0.0617902837880695 GO:0098641 cadherin binding involved in cell-cell adhesion 3/339 18/18639 0.166666666666667 9.16371681415929 0.00397283630374729 0.0617902837880695 GO:0015459 potassium channel regulator activity 5/339 59/18639 0.0847457627118644 4.65951702414879 0.00433234328585526 0.0646314886114325 GO:0070888 E-box binding 5/339 59/18639 0.0847457627118644 4.65951702414879 0.00433234328585526 0.0646314886114325 GO:0023023 MHC protein complex binding 4/339 37/18639 0.108108108108108 5.94403252810332 0.00442305542729813 0.0646650703470986 GO:0043395 heparan sulfate proteoglycan binding 3/339 19/18639 0.157894736842105 8.68141592920354 0.00465480217707629 0.0667188312047602 GO:0001221 transcription coregulator binding 7/339 115/18639 0.0608695652173913 3.34674874951905 0.00507727623391016 0.0713747870574679 GO:0051879 Hsp90 protein binding 4/339 42/18639 0.0952380952380952 5.23640960809102 0.00698291782201562 0.0963115646772344 GO:0050431 transforming growth factor beta binding 3/339 24/18639 0.125 6.87278761061947 0.00909294890583007 0.123091586114107 GO:0004866 endopeptidase inhibitor activity 8/339 161/18639 0.0496894409937888 2.73203979552575 0.00938170513423109 0.12434733898941 GO:0004857 enzyme inhibitor activity 15/339 416/18639 0.0360576923076923 1.98253488767869 0.0095259247379028 0.12434733898941 GO:0043495 protein-membrane adaptor activity 4/339 47/18639 0.0851063829787234 4.67934475616645 0.0103683484746834 0.132969521666553 GO:0005160 transforming growth factor beta receptor binding 3/339 26/18639 0.115384615384615 6.34411164057182 0.0113729451679106 0.138560381962377 GO:0030507 spectrin binding 3/339 26/18639 0.115384615384615 6.34411164057182 0.0113729451679106 0.138560381962377 GO:0043548 phosphatidylinositol 3-kinase binding 3/339 26/18639 0.115384615384615 6.34411164057182 0.0113729451679106 0.138560381962377 GO:0035254 glutamate receptor binding 4/339 49/18639 0.0816326530612245 4.48835109264945 0.011973864309713 0.14349007885902 GO:0035255 ionotropic glutamate receptor binding 3/339 27/18639 0.111111111111111 6.10914454277286 0.0126251485017904 0.148854573464658 GO:0003680 minor groove of adenine-thymine-rich DNA binding 2/339 10/18639 0.2 10.9964601769912 0.0134769346232271 0.153931862649672 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 2/339 10/18639 0.2 10.9964601769912 0.0134769346232271 0.153931862649672 GO:0003743 translation initiation factor activity 4/339 51/18639 0.0784313725490196 4.31233732431025 0.0137305543794828 0.154415926944645 GO:0097718 disordered domain specific binding 3/339 28/18639 0.107142857142857 5.8909608091024 0.0139531137704551 0.154541305548525 GO:0043236 laminin binding 3/339 29/18639 0.103448275862069 5.68782422947818 0.0153574111214339 0.162979199609379 GO:0001618 virus receptor activity 5/339 81/18639 0.0617283950617284 3.39396919042937 0.0160723678202794 0.162979199609379 GO:0003953 NAD+ nucleosidase activity 2/339 11/18639 0.181818181818182 9.99678197908286 0.0162756245847944 0.162979199609379 GO:0048185 activin binding 2/339 11/18639 0.181818181818182 9.99678197908286 0.0162756245847944 0.162979199609379 GO:0050998 nitric-oxide synthase binding 2/339 11/18639 0.181818181818182 9.99678197908286 0.0162756245847944 0.162979199609379 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/339 11/18639 0.181818181818182 9.99678197908286 0.0162756245847944 0.162979199609379 GO:0140031 phosphorylation-dependent protein binding 2/339 11/18639 0.181818181818182 9.99678197908286 0.0162756245847944 0.162979199609379 GO:0140272 exogenous protein binding 5/339 82/18639 0.0609756097560976 3.3525793222534 0.0168689904005214 0.166638270037583 GO:0005095 GTPase inhibitor activity 2/339 12/18639 0.166666666666667 9.16371681415929 0.0192984891916083 0.173722408004439 GO:0070008 serine-type exopeptidase activity 2/339 12/18639 0.166666666666667 9.16371681415929 0.0192984891916083 0.173722408004439 GO:0140829 bicarbonate:monoatomic anion antiporter activity 2/339 12/18639 0.166666666666667 9.16371681415929 0.0192984891916083 0.173722408004439 GO:0140900 chloride:bicarbonate antiporter activity 2/339 12/18639 0.166666666666667 9.16371681415929 0.0192984891916083 0.173722408004439 GO:0009055 electron transfer activity 6/339 116/18639 0.0517241379310345 2.84391211473909 0.0193818019718538 0.173722408004439 GO:0061135 endopeptidase regulator activity 8/339 184/18639 0.0434782608695652 2.39053482108503 0.0196047950209491 0.173722408004439 GO:0004601 peroxidase activity 4/339 57/18639 0.0701754385964912 3.85840707964602 0.019949799612363 0.173722408004439 GO:0015106 bicarbonate transmembrane transporter activity 3/339 32/18639 0.09375 5.1545907079646 0.020032338121618 0.173722408004439 GO:0071813 lipoprotein particle binding 3/339 32/18639 0.09375 5.1545907079646 0.020032338121618 0.173722408004439 GO:0071814 protein-lipid complex binding 3/339 32/18639 0.09375 5.1545907079646 0.020032338121618 0.173722408004439 GO:0005543 phospholipid binding 16/339 497/18639 0.0321931589537223 1.77005395203077 0.0202002800005162 0.173722408004439 GO:0071889 14-3-3 protein binding 3/339 33/18639 0.0909090909090909 4.99839098954143 0.0217454880333149 0.182712089107508 GO:0140311 protein sequestering activity 3/339 33/18639 0.0909090909090909 4.99839098954143 0.0217454880333149 0.182712089107508 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 4/339 59/18639 0.0677966101694915 3.72761361931903 0.0223511034450199 0.183046446178391 GO:0031994 insulin-like growth factor I binding 2/339 13/18639 0.153846153846154 8.45881552076242 0.0225364981614982 0.183046446178391 GO:0051011 microtubule minus-end binding 2/339 13/18639 0.153846153846154 8.45881552076242 0.0225364981614982 0.183046446178391 GO:0031625 ubiquitin protein ligase binding 11/339 302/18639 0.0364238410596026 2.00266658852488 0.0228770483744584 0.183770575403616 GO:0015026 coreceptor activity 4/339 61/18639 0.0655737704918033 3.60539677934136 0.0249213308526783 0.197833528995663 GO:0008236 serine-type peptidase activity 8/339 194/18639 0.0412371134020619 2.26731137669921 0.0258985817890558 0.197833528995663 GO:0008191 metalloendopeptidase inhibitor activity 2/339 14/18639 0.142857142857143 7.85461441213654 0.0259808738489516 0.197833528995663 GO:0032036 myosin heavy chain binding 2/339 14/18639 0.142857142857143 7.85461441213654 0.0259808738489516 0.197833528995663 GO:0044548 S100 protein binding 2/339 14/18639 0.142857142857143 7.85461441213654 0.0259808738489516 0.197833528995663 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 12/339 349/18639 0.0343839541547278 1.89050891294977 0.0266079181903822 0.2005194659502 GO:0042826 histone deacetylase binding 6/339 127/18639 0.047244094488189 2.59758901818689 0.0286850473799028 0.21023762328728 GO:0017171 serine hydrolase activity 8/339 198/18639 0.0404040404040404 2.22150710646286 0.0287710915636091 0.21023762328728 GO:0005041 low-density lipoprotein particle receptor activity 2/339 15/18639 0.133333333333333 7.33097345132743 0.0296230850869902 0.21023762328728 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 2/339 15/18639 0.133333333333333 7.33097345132743 0.0296230850869902 0.21023762328728 GO:0031005 filamin binding 2/339 15/18639 0.133333333333333 7.33097345132743 0.0296230850869902 0.21023762328728 GO:0050780 dopamine receptor binding 2/339 15/18639 0.133333333333333 7.33097345132743 0.0296230850869902 0.21023762328728 GO:0015399 primary active transmembrane transporter activity 7/339 166/18639 0.0421686746987952 2.31853076020898 0.0324168990517265 0.227577678136755 GO:0031072 heat shock protein binding 6/339 131/18639 0.0458015267175573 2.51827332297507 0.0326889961755941 0.227577678136755 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 2/339 16/18639 0.125 6.87278761061947 0.0334548411684296 0.23071215937851 GO:0044389 ubiquitin-like protein ligase binding 11/339 322/18639 0.0341614906832298 1.87827735942395 0.0342424513607571 0.23189629811054 GO:0016247 channel regulator activity 7/339 168/18639 0.0416666666666667 2.29092920353982 0.034261012579943 0.23189629811054 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 4/339 68/18639 0.0588235294117647 3.23425299323269 0.035275834879915 0.236574635754292 GO:0141108 transporter regulator activity 7/339 170/18639 0.0411764705882353 2.26397709526288 0.0361736020345681 0.240390028066084 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/339 17/18639 0.117647058823529 6.46850598646538 0.0374680859635152 0.2445461682083 GO:0008429 phosphatidylethanolamine binding 2/339 17/18639 0.117647058823529 6.46850598646538 0.0374680859635152 0.2445461682083 GO:0008137 NADH dehydrogenase (ubiquinone) activity 3/339 41/18639 0.0731707317073171 4.02309518670408 0.0382311328503351 0.245537165130792 GO:0046982 protein heterodimerization activity 12/339 369/18639 0.032520325203252 1.78804230520181 0.0382917056428321 0.245537165130792 GO:0140030 modification-dependent protein binding 7/339 173/18639 0.0404624277456647 2.22471737684792 0.0391726305997598 0.2490016779863 GO:0019894 kinesin binding 3/339 42/18639 0.0714285714285714 3.92730720606827 0.0406348416986674 0.253748327308258 GO:0031492 nucleosomal DNA binding 3/339 42/18639 0.0714285714285714 3.92730720606827 0.0406348416986674 0.253748327308258 GO:0030228 lipoprotein particle receptor activity 2/339 18/18639 0.111111111111111 6.10914454277286 0.0416549921709862 0.253748327308258 GO:0050811 GABA receptor binding 2/339 18/18639 0.111111111111111 6.10914454277286 0.0416549921709862 0.253748327308258 GO:0070064 proline-rich region binding 2/339 18/18639 0.111111111111111 6.10914454277286 0.0416549921709862 0.253748327308258 GO:0004252 serine-type endopeptidase activity 7/339 176/18639 0.0397727272727273 2.18679605792438 0.0423300396672676 0.255729413196468 GO:0003954 NADH dehydrogenase activity 3/339 44/18639 0.0681818181818182 3.74879324215607 0.0456653589585249 0.269054524931737 GO:0031491 nucleosome binding 4/339 74/18639 0.0540540540540541 2.97201626405166 0.045859948855147 0.269054524931737 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 2/339 19/18639 0.105263157894737 5.78761061946903 0.0460079556996815 0.269054524931737 GO:0005520 insulin-like growth factor binding 2/339 19/18639 0.105263157894737 5.78761061946903 0.0460079556996815 0.269054524931737 GO:0019003 GDP binding 4/339 75/18639 0.0533333333333333 2.93238938053097 0.0477779465570578 0.277187928041343 GO:0043024 ribosomal small subunit binding 2/339 20/18639 0.1 5.49823008849558 0.0505195901778638 0.2907859875592 GO:0140359 ABC-type transporter activity 3/339 47/18639 0.0638297872340425 3.50950856712483 0.0537582827397215 0.304836644165849 GO:0019199 transmembrane receptor protein kinase activity 4/339 78/18639 0.0512820512820513 2.81960517358747 0.0537947019116204 0.304836644165849 GO:0051010 microtubule plus-end binding 2/339 21/18639 0.0952380952380952 5.23640960809102 0.055182721587495 0.310296688311222 GO:0000510 H3-H4 histone complex chaperone activity 6/339 151/18639 0.0397350993377483 2.18472718748169 0.0580420388710356 0.316632316527814 GO:0140584 chromatin extrusion motor activity 6/339 151/18639 0.0397350993377483 2.18472718748169 0.0580420388710356 0.316632316527814 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 6/339 151/18639 0.0397350993377483 2.18472718748169 0.0580420388710356 0.316632316527814 GO:0140849 ATP-dependent H2AZ histone chaperone activity 6/339 151/18639 0.0397350993377483 2.18472718748169 0.0580420388710356 0.316632316527814 GO:0017124 SH3 domain binding 5/339 115/18639 0.0434782608695652 2.39053482108503 0.0589894236936153 0.31774512058689 GO:0015616 DNA translocase activity 6/339 152/18639 0.0394736842105263 2.17035398230089 0.0595500431195676 0.31774512058689 GO:0140674 ATP-dependent histone chaperone activity 6/339 152/18639 0.0394736842105263 2.17035398230089 0.0595500431195676 0.31774512058689 GO:0005096 GTPase activator activity 9/339 271/18639 0.033210332103321 1.8259804721941 0.0603986326922687 0.319937684768467 GO:0061775 cohesin loader activity 6/339 153/18639 0.0392156862745098 2.15616866215513 0.0610812529483655 0.32122586982198 GO:0019208 phosphatase regulator activity 5/339 117/18639 0.0427350427350427 2.34967097798956 0.0625880770421218 0.324481449062348 GO:1990782 protein tyrosine kinase binding 5/339 117/18639 0.0427350427350427 2.34967097798956 0.0625880770421218 0.324481449062348 GO:0022853 active monoatomic ion transmembrane transporter activity 5/339 118/18639 0.0423728813559322 2.3297585120744 0.0644329554067943 0.32736604679689 GO:0008135 translation factor activity, RNA binding 4/339 83/18639 0.0481927710843374 2.64974944023883 0.0646901310469586 0.32736604679689 GO:0004602 glutathione peroxidase activity 2/339 23/18639 0.0869565217391304 4.78106964217007 0.0649358095561546 0.32736604679689 GO:0099186 structural constituent of postsynapse 2/339 23/18639 0.0869565217391304 4.78106964217007 0.0649358095561546 0.32736604679689 GO:0005021 vascular endothelial growth factor receptor activity 3/339 51/18639 0.0588235294117647 3.23425299323269 0.0655356565828813 0.328127157274563 GO:0180051 translation factor activity 4/339 84/18639 0.0476190476190476 2.61820480404551 0.0669976435048611 0.333165152394922 GO:0140658 ATP-dependent chromatin remodeler activity 6/339 158/18639 0.0379746835443038 2.08793547664389 0.0690855376328404 0.341193924712986 GO:0001091 RNA polymerase II general transcription initiation factor binding 2/339 24/18639 0.0833333333333333 4.58185840707965 0.0700124332516387 0.341193924712986 GO:0030215 semaphorin receptor binding 2/339 24/18639 0.0833333333333333 4.58185840707965 0.0700124332516387 0.341193924712986 GO:0016209 antioxidant activity 4/339 86/18639 0.0465116279069767 2.5573163202305 0.0717391766333896 0.343900405639099 GO:0017046 peptide hormone binding 3/339 53/18639 0.0566037735849057 3.11220571046919 0.0718304972884633 0.343900405639099 GO:0003689 DNA clamp loader activity 6/339 160/18639 0.0375 2.06183628318584 0.072449606659947 0.343900405639099 GO:0099106 ion channel regulator activity 6/339 160/18639 0.0375 2.06183628318584 0.072449606659947 0.343900405639099 GO:0003925 G protein activity 3/339 54/18639 0.0555555555555556 3.05457227138643 0.0750759018389152 0.349608714952475 GO:0042974 nuclear retinoic acid receptor binding 2/339 25/18639 0.08 4.39858407079646 0.0752138782521534 0.349608714952475 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 2/339 25/18639 0.08 4.39858407079646 0.0752138782521534 0.349608714952475 GO:0022804 active transmembrane transporter activity 13/339 457/18639 0.0284463894967177 1.56404794639918 0.0755652215629153 0.349608714952475 GO:0016651 oxidoreductase activity, acting on NAD(P)H 4/339 88/18639 0.0454545454545455 2.49919549477072 0.0766475002896522 0.3523856774323 GO:0140313 molecular sequestering activity 3/339 55/18639 0.0545454545454545 2.99903459372486 0.0783851989691739 0.358122377790413 GO:0140713 histone chaperone activity 6/339 164/18639 0.0365853658536585 2.01154759335204 0.0794549730954883 0.359801853744031 GO:0003714 transcription corepressor activity 7/339 204/18639 0.0343137254901961 1.88664757938574 0.0797372097216594 0.359801853744031 GO:0050681 nuclear androgen receptor binding 2/339 26/18639 0.0769230769230769 4.22940776038121 0.0805339560091737 0.361167618666908 GO:0031490 chromatin DNA binding 5/339 128/18639 0.0390625 2.14774612831858 0.0845340141713059 0.376794904629418 GO:0016504 peptidase activator activity 3/339 57/18639 0.0526315789473684 2.89380530973451 0.0851910342863453 0.377422097353445 GO:0043178 alcohol binding 4/339 92/18639 0.0434782608695652 2.39053482108503 0.0869543129238264 0.382913269562151 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 3/339 58/18639 0.0517241379310345 2.84391211473909 0.0886853001972312 0.387781205579799 GO:0051219 phosphoprotein binding 4/339 93/18639 0.043010752688172 2.3648301455895 0.0896310767101208 0.387781205579799 GO:0008094 ATP-dependent activity, acting on DNA 7/339 210/18639 0.0333333333333333 1.83274336283186 0.0896511952708428 0.387781205579799 GO:0045499 chemorepellent activity 2/339 28/18639 0.0714285714285714 3.92730720606827 0.0915061642127881 0.390206546546276 GO:0001786 phosphatidylserine binding 3/339 59/18639 0.0508474576271186 2.79571021448928 0.0922389178803854 0.390206546546276 GO:0045309 protein phosphorylated amino acid binding 3/339 59/18639 0.0508474576271186 2.79571021448928 0.0922389178803854 0.390206546546276 GO:0042562 hormone binding 4/339 94/18639 0.0425531914893617 2.33967237808322 0.092347103355001 0.390206546546276 GO:0004714 transmembrane receptor protein tyrosine kinase activity 3/339 60/18639 0.05 2.74911504424779 0.0958507055597203 0.400382090080889 GO:0098531 ligand-modulated transcription factor activity 3/339 60/18639 0.05 2.74911504424779 0.0958507055597203 0.400382090080889 GO:0051861 glycolipid binding 2/339 29/18639 0.0689655172413793 3.79188281965212 0.0971468125899255 0.403490454563838 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 2/339 30/18639 0.0666666666666667 3.66548672566372 0.102883120769221 0.420153973644139 GO:0051721 protein phosphatase 2A binding 2/339 30/18639 0.0666666666666667 3.66548672566372 0.102883120769221 0.420153973644139 GO:0098918 structural constituent of synapse 2/339 30/18639 0.0666666666666667 3.66548672566372 0.102883120769221 0.420153973644139 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 13/339 484/18639 0.0268595041322314 1.47679733781906 0.105495911163756 0.428430617003919 GO:0005452 solute:inorganic anion antiporter activity 2/339 31/18639 0.0645161290322581 3.54724521838424 0.108709768778922 0.436630994381273 GO:0070325 lipoprotein particle receptor binding 2/339 31/18639 0.0645161290322581 3.54724521838424 0.108709768778922 0.436630994381273 GO:0070851 growth factor receptor binding 5/339 139/18639 0.0359712230215827 1.97778060737251 0.110006289474951 0.439424030634915 GO:0030695 GTPase regulator activity 13/339 489/18639 0.0265848670756646 1.46169716054075 0.111723374230459 0.443857535665572 GO:0060589 nucleoside-triphosphatase regulator activity 13/339 490/18639 0.026530612244898 1.45871410511107 0.112994444085916 0.446480749334081 GO:0001216 DNA-binding transcription activator activity 13/339 491/18639 0.0264765784114053 1.45574320062001 0.114274018975939 0.449109182104361 GO:0008238 exopeptidase activity 4/339 102/18639 0.0392156862745098 2.15616866215513 0.115437841278291 0.451257015906045 GO:0008237 metallopeptidase activity 6/339 184/18639 0.0326086956521739 1.79290111581377 0.119889941408539 0.466167804093839 GO:0030296 protein tyrosine kinase activator activity 2/339 33/18639 0.0606060606060606 3.33226065969429 0.120613604551092 0.466500237708192 GO:0004175 endopeptidase activity 11/339 405/18639 0.0271604938271605 1.49334644378892 0.122148242551654 0.46994929108031 GO:0008376 acetylgalactosaminyltransferase activity 2/339 34/18639 0.0588235294117647 3.23425299323269 0.126680940426157 0.479812266588189 GO:0016831 carboxy-lyase activity 2/339 34/18639 0.0588235294117647 3.23425299323269 0.126680940426157 0.479812266588189 GO:0030332 cyclin binding 2/339 34/18639 0.0588235294117647 3.23425299323269 0.126680940426157 0.479812266588189 GO:0008013 beta-catenin binding 4/339 106/18639 0.0377358490566038 2.07480380697946 0.127843461700719 0.481719435583639 GO:0140597 protein carrier chaperone 6/339 188/18639 0.0319148936170213 1.75475428356242 0.129012787674034 0.483632552767788 GO:0005126 cytokine receptor binding 8/339 275/18639 0.0290909090909091 1.59948511665326 0.130048482358241 0.483748867522063 GO:0002039 p53 binding 3/339 69/18639 0.0434782608695652 2.39053482108503 0.13077318470487 0.483748867522063 GO:0019888 protein phosphatase regulator activity 4/339 107/18639 0.0373831775700935 2.05541311719461 0.131029105019656 0.483748867522063 GO:0019902 phosphatase binding 6/339 190/18639 0.0315789473684211 1.73628318584071 0.133696632552472 0.491116775858579 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/339 36/18639 0.0555555555555556 3.05457227138643 0.139022941355129 0.508128850652995 GO:0016887 ATP hydrolysis activity 11/339 417/18639 0.026378896882494 1.45037244540651 0.140697009394854 0.509455459281364 GO:0004222 metalloendopeptidase activity 4/339 110/18639 0.0363636363636364 1.99935639581657 0.140779757557915 0.509455459281364 GO:0043539 protein serine/threonine kinase activator activity 3/339 73/18639 0.0410958904109589 2.25954661171051 0.147538743130172 0.516251621465841 GO:0035091 phosphatidylinositol binding 8/339 284/18639 0.028169014084507 1.54879720802692 0.147730522573977 0.516251621465841 GO:0000146 microfilament motor activity 2/339 38/18639 0.0526315789473684 2.89380530973451 0.151611715133222 0.516251621465841 GO:0043531 ADP binding 2/339 38/18639 0.0526315789473684 2.89380530973451 0.151611715133222 0.516251621465841 GO:0000217 DNA secondary structure binding 2/339 39/18639 0.0512820512820513 2.81960517358747 0.157988034042 0.516251621465841 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 2/339 39/18639 0.0512820512820513 2.81960517358747 0.157988034042 0.516251621465841 GO:0017022 myosin binding 3/339 76/18639 0.0394736842105263 2.17035398230089 0.160544616069093 0.516251621465841 GO:0003724 RNA helicase activity 3/339 77/18639 0.038961038961039 2.14216756694633 0.164955393799545 0.516251621465841 GO:0001094 TFIID-class transcription factor complex binding 1/339 10/18639 0.1 5.49823008849558 0.167727808274224 0.516251621465841 GO:0004382 GDP phosphatase activity 1/339 10/18639 0.1 5.49823008849558 0.167727808274224 0.516251621465841 GO:0004955 prostaglandin receptor activity 1/339 10/18639 0.1 5.49823008849558 0.167727808274224 0.516251621465841 GO:0005131 growth hormone receptor binding 1/339 10/18639 0.1 5.49823008849558 0.167727808274224 0.516251621465841 GO:0005381 iron ion transmembrane transporter activity 1/339 10/18639 0.1 5.49823008849558 0.167727808274224 0.516251621465841 GO:0005522 profilin binding 1/339 10/18639 0.1 5.49823008849558 0.167727808274224 0.516251621465841 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/339 10/18639 0.1 5.49823008849558 0.167727808274224 0.516251621465841 GO:0019531 oxalate transmembrane transporter activity 1/339 10/18639 0.1 5.49823008849558 0.167727808274224 0.516251621465841 GO:0030957 Tat protein binding 1/339 10/18639 0.1 5.49823008849558 0.167727808274224 0.516251621465841 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/339 10/18639 0.1 5.49823008849558 0.167727808274224 0.516251621465841 GO:0031720 haptoglobin binding 1/339 10/18639 0.1 5.49823008849558 0.167727808274224 0.516251621465841 GO:0032395 MHC class II receptor activity 1/339 10/18639 0.1 5.49823008849558 0.167727808274224 0.516251621465841 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/339 10/18639 0.1 5.49823008849558 0.167727808274224 0.516251621465841 GO:0035374 chondroitin sulfate binding 1/339 10/18639 0.1 5.49823008849558 0.167727808274224 0.516251621465841 GO:0042975 peroxisome proliferator activated receptor binding 1/339 10/18639 0.1 5.49823008849558 0.167727808274224 0.516251621465841 GO:0043208 glycosphingolipid binding 1/339 10/18639 0.1 5.49823008849558 0.167727808274224 0.516251621465841 GO:0050815 phosphoserine residue binding 1/339 10/18639 0.1 5.49823008849558 0.167727808274224 0.516251621465841 GO:0070513 death domain binding 1/339 10/18639 0.1 5.49823008849558 0.167727808274224 0.516251621465841 GO:0140940 histone H2A methyltransferase activity 1/339 10/18639 0.1 5.49823008849558 0.167727808274224 0.516251621465841 GO:0141109 transporter activator activity 1/339 10/18639 0.1 5.49823008849558 0.167727808274224 0.516251621465841 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/339 10/18639 0.1 5.49823008849558 0.167727808274224 0.516251621465841 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/339 10/18639 0.1 5.49823008849558 0.167727808274224 0.516251621465841 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/339 10/18639 0.1 5.49823008849558 0.167727808274224 0.516251621465841 GO:1990259 histone H2AQ104 methyltransferase activity 1/339 10/18639 0.1 5.49823008849558 0.167727808274224 0.516251621465841 GO:0140104 molecular carrier activity 7/339 249/18639 0.0281124497991968 1.54568717347265 0.169588836796019 0.516251621465841 GO:0001530 lipopolysaccharide binding 2/339 41/18639 0.0487804878048781 2.68206345780272 0.170884477542571 0.516251621465841 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 2/339 41/18639 0.0487804878048781 2.68206345780272 0.170884477542571 0.516251621465841 GO:0042169 SH2 domain binding 2/339 41/18639 0.0487804878048781 2.68206345780272 0.170884477542571 0.516251621465841 GO:0008186 ATP-dependent activity, acting on RNA 3/339 79/18639 0.0379746835443038 2.08793547664389 0.17388265087551 0.516251621465841 GO:0046332 SMAD binding 3/339 79/18639 0.0379746835443038 2.08793547664389 0.17388265087551 0.516251621465841 GO:0048487 beta-tubulin binding 2/339 42/18639 0.0476190476190476 2.61820480404551 0.177396959334766 0.516251621465841 GO:0002162 dystroglycan binding 1/339 11/18639 0.0909090909090909 4.99839098954143 0.182873026643167 0.516251621465841 GO:0004954 prostanoid receptor activity 1/339 11/18639 0.0909090909090909 4.99839098954143 0.182873026643167 0.516251621465841 GO:0008046 axon guidance receptor activity 1/339 11/18639 0.0909090909090909 4.99839098954143 0.182873026643167 0.516251621465841 GO:0008172 S-methyltransferase activity 1/339 11/18639 0.0909090909090909 4.99839098954143 0.182873026643167 0.516251621465841 GO:0008271 secondary active sulfate transmembrane transporter activity 1/339 11/18639 0.0909090909090909 4.99839098954143 0.182873026643167 0.516251621465841 GO:0010854 adenylate cyclase regulator activity 1/339 11/18639 0.0909090909090909 4.99839098954143 0.182873026643167 0.516251621465841 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/339 11/18639 0.0909090909090909 4.99839098954143 0.182873026643167 0.516251621465841 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/339 11/18639 0.0909090909090909 4.99839098954143 0.182873026643167 0.516251621465841 GO:0019107 myristoyltransferase activity 1/339 11/18639 0.0909090909090909 4.99839098954143 0.182873026643167 0.516251621465841 GO:0032050 clathrin heavy chain binding 1/339 11/18639 0.0909090909090909 4.99839098954143 0.182873026643167 0.516251621465841 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/339 11/18639 0.0909090909090909 4.99839098954143 0.182873026643167 0.516251621465841 GO:0034713 type I transforming growth factor beta receptor binding 1/339 11/18639 0.0909090909090909 4.99839098954143 0.182873026643167 0.516251621465841 GO:0042608 T cell receptor binding 1/339 11/18639 0.0909090909090909 4.99839098954143 0.182873026643167 0.516251621465841 GO:0045294 alpha-catenin binding 1/339 11/18639 0.0909090909090909 4.99839098954143 0.182873026643167 0.516251621465841 GO:0140537 transcription regulator activator activity 1/339 11/18639 0.0909090909090909 4.99839098954143 0.182873026643167 0.516251621465841 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/339 11/18639 0.0909090909090909 4.99839098954143 0.182873026643167 0.516251621465841 GO:0030971 receptor tyrosine kinase binding 3/339 81/18639 0.037037037037037 2.03638151425762 0.182942553835412 0.516251621465841 GO:0016248 channel inhibitor activity 2/339 44/18639 0.0454545454545455 2.49919549477072 0.1905322483651 0.516251621465841 GO:0042605 peptide antigen binding 2/339 45/18639 0.0444444444444444 2.44365781710914 0.197148129520413 0.516251621465841 GO:0141110 transporter inhibitor activity 2/339 45/18639 0.0444444444444444 2.44365781710914 0.197148129520413 0.516251621465841 GO:0005025 transforming growth factor beta receptor activity, type I 1/339 12/18639 0.0833333333333333 4.58185840707965 0.197743439138763 0.516251621465841 GO:0005026 transforming growth factor beta receptor activity, type II 1/339 12/18639 0.0833333333333333 4.58185840707965 0.197743439138763 0.516251621465841 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/339 12/18639 0.0833333333333333 4.58185840707965 0.197743439138763 0.516251621465841 GO:0015166 polyol transmembrane transporter activity 1/339 12/18639 0.0833333333333333 4.58185840707965 0.197743439138763 0.516251621465841 GO:0015368 calcium:monoatomic cation antiporter activity 1/339 12/18639 0.0833333333333333 4.58185840707965 0.197743439138763 0.516251621465841 GO:0016208 AMP binding 1/339 12/18639 0.0833333333333333 4.58185840707965 0.197743439138763 0.516251621465841 GO:0016273 arginine N-methyltransferase activity 1/339 12/18639 0.0833333333333333 4.58185840707965 0.197743439138763 0.516251621465841 GO:0016274 protein-arginine N-methyltransferase activity 1/339 12/18639 0.0833333333333333 4.58185840707965 0.197743439138763 0.516251621465841 GO:0016361 activin receptor activity, type I 1/339 12/18639 0.0833333333333333 4.58185840707965 0.197743439138763 0.516251621465841 GO:0016362 activin receptor activity, type II 1/339 12/18639 0.0833333333333333 4.58185840707965 0.197743439138763 0.516251621465841 GO:0017002 activin receptor activity 1/339 12/18639 0.0833333333333333 4.58185840707965 0.197743439138763 0.516251621465841 GO:0017166 vinculin binding 1/339 12/18639 0.0833333333333333 4.58185840707965 0.197743439138763 0.516251621465841 GO:0034452 dynactin binding 1/339 12/18639 0.0833333333333333 4.58185840707965 0.197743439138763 0.516251621465841 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/339 12/18639 0.0833333333333333 4.58185840707965 0.197743439138763 0.516251621465841 GO:0035497 cAMP response element binding 1/339 12/18639 0.0833333333333333 4.58185840707965 0.197743439138763 0.516251621465841 GO:0036009 protein-glutamine N-methyltransferase activity 1/339 12/18639 0.0833333333333333 4.58185840707965 0.197743439138763 0.516251621465841 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/339 12/18639 0.0833333333333333 4.58185840707965 0.197743439138763 0.516251621465841 GO:0070679 inositol 1,4,5 trisphosphate binding 1/339 12/18639 0.0833333333333333 4.58185840707965 0.197743439138763 0.516251621465841 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/339 12/18639 0.0833333333333333 4.58185840707965 0.197743439138763 0.516251621465841 GO:0004180 carboxypeptidase activity 2/339 46/18639 0.0434782608695652 2.39053482108503 0.203791739386455 0.52618127739537 GO:0030276 clathrin binding 2/339 46/18639 0.0434782608695652 2.39053482108503 0.203791739386455 0.52618127739537 GO:0035591 signaling adaptor activity 4/339 129/18639 0.0310077519379845 1.70487754682033 0.208378230865467 0.52618127739537 GO:0001784 phosphotyrosine residue binding 2/339 47/18639 0.0425531914893617 2.33967237808322 0.210459893015199 0.52618127739537 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 4/339 130/18639 0.0307692307692308 1.69176310415248 0.212170903753132 0.52618127739537 GO:0004465 lipoprotein lipase activity 1/339 13/18639 0.0769230769230769 4.22940776038121 0.212344017553535 0.52618127739537 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/339 13/18639 0.0769230769230769 4.22940776038121 0.212344017553535 0.52618127739537 GO:0005338 nucleotide-sugar transmembrane transporter activity 1/339 13/18639 0.0769230769230769 4.22940776038121 0.212344017553535 0.52618127739537 GO:0017154 semaphorin receptor activity 1/339 13/18639 0.0769230769230769 4.22940776038121 0.212344017553535 0.52618127739537 GO:0043560 insulin receptor substrate binding 1/339 13/18639 0.0769230769230769 4.22940776038121 0.212344017553535 0.52618127739537 GO:0070123 transforming growth factor beta receptor activity, type III 1/339 13/18639 0.0769230769230769 4.22940776038121 0.212344017553535 0.52618127739537 GO:0070700 BMP receptor binding 1/339 13/18639 0.0769230769230769 4.22940776038121 0.212344017553535 0.52618127739537 GO:0071837 HMG box domain binding 1/339 13/18639 0.0769230769230769 4.22940776038121 0.212344017553535 0.52618127739537 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/339 13/18639 0.0769230769230769 4.22940776038121 0.212344017553535 0.52618127739537 GO:0140666 annealing activity 1/339 13/18639 0.0769230769230769 4.22940776038121 0.212344017553535 0.52618127739537 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2/339 48/18639 0.0416666666666667 2.29092920353982 0.217149511494346 0.527750988480885 GO:0005004 GPI-linked ephrin receptor activity 2/339 49/18639 0.0408163265306122 2.24417554632472 0.223857619163099 0.527750988480885 GO:0005008 hepatocyte growth factor receptor activity 2/339 49/18639 0.0408163265306122 2.24417554632472 0.223857619163099 0.527750988480885 GO:0005009 insulin receptor activity 2/339 49/18639 0.0408163265306122 2.24417554632472 0.223857619163099 0.527750988480885 GO:0005011 macrophage colony-stimulating factor receptor activity 2/339 49/18639 0.0408163265306122 2.24417554632472 0.223857619163099 0.527750988480885 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/339 49/18639 0.0408163265306122 2.24417554632472 0.223857619163099 0.527750988480885 GO:0005020 stem cell factor receptor activity 2/339 49/18639 0.0408163265306122 2.24417554632472 0.223857619163099 0.527750988480885 GO:0008288 boss receptor activity 2/339 49/18639 0.0408163265306122 2.24417554632472 0.223857619163099 0.527750988480885 GO:0036332 placental growth factor receptor activity 2/339 49/18639 0.0408163265306122 2.24417554632472 0.223857619163099 0.527750988480885 GO:0038062 protein tyrosine kinase collagen receptor activity 2/339 49/18639 0.0408163265306122 2.24417554632472 0.223857619163099 0.527750988480885 GO:0060175 brain-derived neurotrophic factor receptor activity 2/339 49/18639 0.0408163265306122 2.24417554632472 0.223857619163099 0.527750988480885 GO:0005344 oxygen carrier activity 1/339 14/18639 0.0714285714285714 3.92730720606827 0.226679643992349 0.527750988480885 GO:0008559 ABC-type xenobiotic transporter activity 1/339 14/18639 0.0714285714285714 3.92730720606827 0.226679643992349 0.527750988480885 GO:0071933 Arp2/3 complex binding 1/339 14/18639 0.0714285714285714 3.92730720606827 0.226679643992349 0.527750988480885 GO:0098821 BMP receptor activity 1/339 14/18639 0.0714285714285714 3.92730720606827 0.226679643992349 0.527750988480885 GO:1901474 azole transmembrane transporter activity 1/339 14/18639 0.0714285714285714 3.92730720606827 0.226679643992349 0.527750988480885 GO:0072341 modified amino acid binding 3/339 91/18639 0.032967032967033 1.81260332587766 0.22989195775599 0.527750988480885 GO:0005006 epidermal growth factor receptor activity 2/339 50/18639 0.04 2.19929203539823 0.230581340893656 0.527750988480885 GO:0005007 fibroblast growth factor receptor activity 2/339 50/18639 0.04 2.19929203539823 0.230581340893656 0.527750988480885 GO:0005017 platelet-derived growth factor receptor activity 2/339 50/18639 0.04 2.19929203539823 0.230581340893656 0.527750988480885 GO:0005019 platelet-derived growth factor beta-receptor activity 2/339 50/18639 0.04 2.19929203539823 0.230581340893656 0.527750988480885 GO:0015297 antiporter activity 4/339 135/18639 0.0296296296296296 1.6291052114061 0.231412227308317 0.527750988480885 GO:0005010 insulin-like growth factor receptor activity 2/339 51/18639 0.0392156862745098 2.15616866215513 0.237317899436953 0.527750988480885 GO:0005030 neurotrophin receptor activity 2/339 51/18639 0.0392156862745098 2.15616866215513 0.237317899436953 0.527750988480885 GO:0016830 carbon-carbon lyase activity 2/339 51/18639 0.0392156862745098 2.15616866215513 0.237317899436953 0.527750988480885 GO:0016922 nuclear receptor binding 4/339 137/18639 0.0291970802919708 1.60532265357535 0.239227391632782 0.527750988480885 GO:0004129 cytochrome-c oxidase activity 1/339 15/18639 0.0666666666666667 3.66548672566372 0.240755112485589 0.527750988480885 GO:0004953 icosanoid receptor activity 1/339 15/18639 0.0666666666666667 3.66548672566372 0.240755112485589 0.527750988480885 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/339 15/18639 0.0666666666666667 3.66548672566372 0.240755112485589 0.527750988480885 GO:0005523 tropomyosin binding 1/339 15/18639 0.0666666666666667 3.66548672566372 0.240755112485589 0.527750988480885 GO:0015116 sulfate transmembrane transporter activity 1/339 15/18639 0.0666666666666667 3.66548672566372 0.240755112485589 0.527750988480885 GO:0017081 chloride channel regulator activity 1/339 15/18639 0.0666666666666667 3.66548672566372 0.240755112485589 0.527750988480885 GO:0045504 dynein heavy chain binding 1/339 15/18639 0.0666666666666667 3.66548672566372 0.240755112485589 0.527750988480885 GO:0048531 beta-1,3-galactosyltransferase activity 1/339 15/18639 0.0666666666666667 3.66548672566372 0.240755112485589 0.527750988480885 GO:0140776 protein-containing complex destabilizing activity 1/339 15/18639 0.0666666666666667 3.66548672566372 0.240755112485589 0.527750988480885 GO:0141050 histone H3K deacetylase activity 1/339 15/18639 0.0666666666666667 3.66548672566372 0.240755112485589 0.527750988480885 GO:0141051 histone H4K deacetylase activity 1/339 15/18639 0.0666666666666667 3.66548672566372 0.240755112485589 0.527750988480885 GO:0001217 DNA-binding transcription repressor activity 7/339 278/18639 0.0251798561151079 1.38444642516076 0.24370354604186 0.527750988480885 GO:0030159 signaling receptor complex adaptor activity 2/339 52/18639 0.0384615384615385 2.11470388019061 0.244064612831249 0.527750988480885 GO:0030295 protein kinase activator activity 4/339 139/18639 0.0287769784172662 1.58222448589801 0.247103272104798 0.527750988480885 GO:0015078 proton transmembrane transporter activity 5/339 185/18639 0.027027027027027 1.48600813202583 0.247587125349837 0.527750988480885 GO:0004867 serine-type endopeptidase inhibitor activity 3/339 95/18639 0.0315789473684211 1.73628318584071 0.249267132812382 0.527750988480885 GO:0004864 protein phosphatase inhibitor activity 2/339 53/18639 0.0377358490566038 2.07480380697946 0.250818891872143 0.527750988480885 GO:0005003 ephrin receptor activity 2/339 53/18639 0.0377358490566038 2.07480380697946 0.250818891872143 0.527750988480885 GO:0005005 transmembrane-ephrin receptor activity 2/339 53/18639 0.0377358490566038 2.07480380697946 0.250818891872143 0.527750988480885 GO:0038064 collagen receptor activity 2/339 53/18639 0.0377358490566038 2.07480380697946 0.250818891872143 0.527750988480885 GO:0140296 general transcription initiation factor binding 2/339 53/18639 0.0377358490566038 2.07480380697946 0.250818891872143 0.527750988480885 GO:0004713 protein tyrosine kinase activity 4/339 140/18639 0.0285714285714286 1.57092288242731 0.25106251962383 0.527750988480885 GO:0005125 cytokine activity 6/339 234/18639 0.0256410256410256 1.40980258679374 0.254095072615316 0.527750988480885 GO:0016407 acetyltransferase activity 3/339 96/18639 0.03125 1.71819690265487 0.254150094584698 0.527750988480885 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 1/339 16/18639 0.0625 3.43639380530973 0.2545751305734 0.527750988480885 GO:0005024 transforming growth factor beta receptor activity 1/339 16/18639 0.0625 3.43639380530973 0.2545751305734 0.527750988480885 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/339 16/18639 0.0625 3.43639380530973 0.2545751305734 0.527750988480885 GO:0019841 retinol binding 1/339 16/18639 0.0625 3.43639380530973 0.2545751305734 0.527750988480885 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/339 16/18639 0.0625 3.43639380530973 0.2545751305734 0.527750988480885 GO:0070411 I-SMAD binding 1/339 16/18639 0.0625 3.43639380530973 0.2545751305734 0.527750988480885 GO:0015485 cholesterol binding 2/339 54/18639 0.037037037037037 2.03638151425762 0.257578237642652 0.527750988480885 GO:0051287 NAD binding 2/339 54/18639 0.037037037037037 2.03638151425762 0.257578237642652 0.527750988480885 GO:0042626 ATPase-coupled transmembrane transporter activity 3/339 98/18639 0.0306122448979592 1.68313165974354 0.263955566288347 0.527750988480885 GO:0019903 protein phosphatase binding 4/339 144/18639 0.0277777777777778 1.52728613569322 0.26702805532935 0.527750988480885 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/339 17/18639 0.0588235294117647 3.23425299323269 0.268144320861518 0.527750988480885 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/339 17/18639 0.0588235294117647 3.23425299323269 0.268144320861518 0.527750988480885 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/339 17/18639 0.0588235294117647 3.23425299323269 0.268144320861518 0.527750988480885 GO:0005092 GDP-dissociation inhibitor activity 1/339 17/18639 0.0588235294117647 3.23425299323269 0.268144320861518 0.527750988480885 GO:0015278 intracellularly gated calcium channel activity 1/339 17/18639 0.0588235294117647 3.23425299323269 0.268144320861518 0.527750988480885 GO:0016018 cyclosporin A binding 1/339 17/18639 0.0588235294117647 3.23425299323269 0.268144320861518 0.527750988480885 GO:0016805 dipeptidase activity 1/339 17/18639 0.0588235294117647 3.23425299323269 0.268144320861518 0.527750988480885 GO:0017110 nucleoside diphosphate phosphatase activity 1/339 17/18639 0.0588235294117647 3.23425299323269 0.268144320861518 0.527750988480885 GO:0019198 transmembrane receptor protein phosphatase activity 1/339 17/18639 0.0588235294117647 3.23425299323269 0.268144320861518 0.527750988480885 GO:0030169 low-density lipoprotein particle binding 1/339 17/18639 0.0588235294117647 3.23425299323269 0.268144320861518 0.527750988480885 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/339 17/18639 0.0588235294117647 3.23425299323269 0.268144320861518 0.527750988480885 GO:0032183 SUMO binding 1/339 17/18639 0.0588235294117647 3.23425299323269 0.268144320861518 0.527750988480885 GO:0038191 neuropilin binding 1/339 17/18639 0.0588235294117647 3.23425299323269 0.268144320861518 0.527750988480885 GO:0051787 misfolded protein binding 1/339 17/18639 0.0588235294117647 3.23425299323269 0.268144320861518 0.527750988480885 GO:0070403 NAD+ binding 1/339 17/18639 0.0588235294117647 3.23425299323269 0.268144320861518 0.527750988480885 GO:1990226 histone methyltransferase binding 1/339 17/18639 0.0588235294117647 3.23425299323269 0.268144320861518 0.527750988480885 GO:0019207 kinase regulator activity 7/339 287/18639 0.024390243902439 1.34103172890136 0.26856821848822 0.527750988480885 GO:0008194 UDP-glycosyltransferase activity 4/339 145/18639 0.0275862068965517 1.51675312786085 0.271048711605245 0.529882297339805 GO:0019212 phosphatase inhibitor activity 2/339 56/18639 0.0357142857142857 1.96365360303413 0.271102570731993 0.529882297339805 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/339 18/18639 0.0555555555555556 3.05457227138643 0.281467222549196 0.541454051798585 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/339 18/18639 0.0555555555555556 3.05457227138643 0.281467222549196 0.541454051798585 GO:0016854 racemase and epimerase activity 1/339 18/18639 0.0555555555555556 3.05457227138643 0.281467222549196 0.541454051798585 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/339 18/18639 0.0555555555555556 3.05457227138643 0.281467222549196 0.541454051798585 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/339 18/18639 0.0555555555555556 3.05457227138643 0.281467222549196 0.541454051798585 GO:1990381 ubiquitin-specific protease binding 1/339 18/18639 0.0555555555555556 3.05457227138643 0.281467222549196 0.541454051798585 GO:0019209 kinase activator activity 4/339 148/18639 0.027027027027027 1.48600813202583 0.28317188823764 0.543303544098988 GO:0004879 nuclear receptor activity 2/339 59/18639 0.0338983050847458 1.86380680965952 0.291369526432441 0.553508488770253 GO:0031593 polyubiquitin modification-dependent protein binding 2/339 59/18639 0.0338983050847458 1.86380680965952 0.291369526432441 0.553508488770253 GO:0003712 transcription coregulator activity 11/339 495/18639 0.0222222222222222 1.22182890855457 0.291611280853151 0.553508488770253 GO:0016918 retinal binding 1/339 19/18639 0.0526315789473684 2.89380530973451 0.294548292929724 0.553508488770253 GO:0030506 ankyrin binding 1/339 19/18639 0.0526315789473684 2.89380530973451 0.294548292929724 0.553508488770253 GO:0034987 immunoglobulin receptor binding 1/339 19/18639 0.0526315789473684 2.89380530973451 0.294548292929724 0.553508488770253 GO:0097001 ceramide binding 1/339 19/18639 0.0526315789473684 2.89380530973451 0.294548292929724 0.553508488770253 GO:0140036 ubiquitin-modified protein reader activity 1/339 19/18639 0.0526315789473684 2.89380530973451 0.294548292929724 0.553508488770253 GO:0001098 basal transcription machinery binding 2/339 60/18639 0.0333333333333333 1.83274336283186 0.298111554738396 0.55733899364135 GO:0001099 basal RNA polymerase II transcription machinery binding 2/339 60/18639 0.0333333333333333 1.83274336283186 0.298111554738396 0.55733899364135 GO:0003774 cytoskeletal motor activity 4/339 153/18639 0.0261437908496732 1.43744577477009 0.303548014977337 0.566055099358248 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 1/339 20/18639 0.05 2.74911504424779 0.307391908864033 0.567433043887899 GO:0010851 cyclase regulator activity 1/339 20/18639 0.05 2.74911504424779 0.307391908864033 0.567433043887899 GO:0016004 phospholipase activator activity 1/339 20/18639 0.05 2.74911504424779 0.307391908864033 0.567433043887899 GO:0140939 histone H4 methyltransferase activity 1/339 20/18639 0.05 2.74911504424779 0.307391908864033 0.567433043887899 GO:0004386 helicase activity 4/339 155/18639 0.0258064516129032 1.4188980873537 0.311745614353725 0.574020262197917 GO:1901682 sulfur compound transmembrane transporter activity 2/339 63/18639 0.0317460317460317 1.74546986936367 0.318269716553555 0.580450945842594 GO:0019887 protein kinase regulator activity 6/339 255/18639 0.0235294117647059 1.29370119729308 0.319737437214824 0.580450945842594 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/339 21/18639 0.0476190476190476 2.61820480404551 0.32000236822786 0.580450945842594 GO:0019200 carbohydrate kinase activity 1/339 21/18639 0.0476190476190476 2.61820480404551 0.32000236822786 0.580450945842594 GO:0035613 RNA stem-loop binding 1/339 21/18639 0.0476190476190476 2.61820480404551 0.32000236822786 0.580450945842594 GO:0072542 protein phosphatase activator activity 1/339 21/18639 0.0476190476190476 2.61820480404551 0.32000236822786 0.580450945842594 GO:0003713 transcription coactivator activity 6/339 256/18639 0.0234375 1.28864767699115 0.32293510666584 0.584320700427547 GO:0038024 cargo receptor activity 2/339 65/18639 0.0307692307692308 1.69176310415248 0.331634171248112 0.586890397498536 GO:0004407 histone deacetylase activity 1/339 22/18639 0.0454545454545455 2.49919549477072 0.33238389133296 0.586890397498536 GO:0008093 cytoskeletal anchor activity 1/339 22/18639 0.0454545454545455 2.49919549477072 0.33238389133296 0.586890397498536 GO:0008970 phospholipase A1 activity 1/339 22/18639 0.0454545454545455 2.49919549477072 0.33238389133296 0.586890397498536 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/339 22/18639 0.0454545454545455 2.49919549477072 0.33238389133296 0.586890397498536 GO:0031683 G-protein beta/gamma-subunit complex binding 1/339 22/18639 0.0454545454545455 2.49919549477072 0.33238389133296 0.586890397498536 GO:0033558 protein lysine deacetylase activity 1/339 22/18639 0.0454545454545455 2.49919549477072 0.33238389133296 0.586890397498536 GO:0034062 5'-3' RNA polymerase activity 1/339 22/18639 0.0454545454545455 2.49919549477072 0.33238389133296 0.586890397498536 GO:0097747 RNA polymerase activity 1/339 22/18639 0.0454545454545455 2.49919549477072 0.33238389133296 0.586890397498536 GO:0140035 ubiquitin-like protein reader activity 1/339 22/18639 0.0454545454545455 2.49919549477072 0.33238389133296 0.586890397498536 GO:0043022 ribosome binding 3/339 112/18639 0.0267857142857143 1.4727402022756 0.333442075868689 0.587340138457859 GO:0008235 metalloexopeptidase activity 2/339 66/18639 0.0303030303030303 1.66613032984714 0.338289141793959 0.590894369449326 GO:0008171 O-methyltransferase activity 1/339 23/18639 0.0434782608695652 2.39053482108503 0.344540622322815 0.590894369449326 GO:0017134 fibroblast growth factor binding 1/339 23/18639 0.0434782608695652 2.39053482108503 0.344540622322815 0.590894369449326 GO:0031681 G-protein beta-subunit binding 1/339 23/18639 0.0434782608695652 2.39053482108503 0.344540622322815 0.590894369449326 GO:0042171 lysophosphatidic acid acyltransferase activity 1/339 23/18639 0.0434782608695652 2.39053482108503 0.344540622322815 0.590894369449326 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/339 23/18639 0.0434782608695652 2.39053482108503 0.344540622322815 0.590894369449326 GO:0070577 lysine-acetylated histone binding 1/339 23/18639 0.0434782608695652 2.39053482108503 0.344540622322815 0.590894369449326 GO:0071617 lysophospholipid acyltransferase activity 1/339 23/18639 0.0434782608695652 2.39053482108503 0.344540622322815 0.590894369449326 GO:0016500 protein-hormone receptor activity 2/339 67/18639 0.0298507462686567 1.64126271298375 0.344923886878584 0.590894369449326 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 2/339 67/18639 0.0298507462686567 1.64126271298375 0.344923886878584 0.590894369449326 GO:0035401 histone H3Y41 kinase activity 3/339 115/18639 0.0260869565217391 1.43432089265102 0.348377292348788 0.590894369449326 GO:0140801 histone H2AXY142 kinase activity 3/339 115/18639 0.0260869565217391 1.43432089265102 0.348377292348788 0.590894369449326 GO:0030145 manganese ion binding 2/339 68/18639 0.0294117647058824 1.61712649661635 0.351536942891069 0.590894369449326 GO:0032934 sterol binding 2/339 68/18639 0.0294117647058824 1.61712649661635 0.351536942891069 0.590894369449326 GO:0015103 inorganic anion transmembrane transporter activity 4/339 165/18639 0.0242424242424242 1.33290426387772 0.352961393270937 0.590894369449326 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/339 24/18639 0.0416666666666667 2.29092920353982 0.356476630543301 0.590894369449326 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/339 24/18639 0.0416666666666667 2.29092920353982 0.356476630543301 0.590894369449326 GO:0004806 triacylglycerol lipase activity 1/339 24/18639 0.0416666666666667 2.29092920353982 0.356476630543301 0.590894369449326 GO:0015149 hexose transmembrane transporter activity 1/339 24/18639 0.0416666666666667 2.29092920353982 0.356476630543301 0.590894369449326 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/339 24/18639 0.0416666666666667 2.29092920353982 0.356476630543301 0.590894369449326 GO:0048027 mRNA 5'-UTR binding 1/339 24/18639 0.0416666666666667 2.29092920353982 0.356476630543301 0.590894369449326 GO:0055056 D-glucose transmembrane transporter activity 1/339 24/18639 0.0416666666666667 2.29092920353982 0.356476630543301 0.590894369449326 GO:0060229 lipase activator activity 1/339 24/18639 0.0416666666666667 2.29092920353982 0.356476630543301 0.590894369449326 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/339 24/18639 0.0416666666666667 2.29092920353982 0.356476630543301 0.590894369449326 GO:0070840 dynein complex binding 1/339 24/18639 0.0416666666666667 2.29092920353982 0.356476630543301 0.590894369449326 GO:0140033 acetylation-dependent protein binding 1/339 24/18639 0.0416666666666667 2.29092920353982 0.356476630543301 0.590894369449326 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 6/339 268/18639 0.0223880597014925 1.23094703473782 0.361598145533605 0.598027702228655 GO:0003707 nuclear steroid receptor activity 1/339 25/18639 0.04 2.19929203539823 0.368195911888765 0.600783954443498 GO:0015645 fatty acid ligase activity 1/339 25/18639 0.04 2.19929203539823 0.368195911888765 0.600783954443498 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/339 25/18639 0.04 2.19929203539823 0.368195911888765 0.600783954443498 GO:0017025 TBP-class protein binding 1/339 25/18639 0.04 2.19929203539823 0.368195911888765 0.600783954443498 GO:0019211 phosphatase activator activity 1/339 25/18639 0.04 2.19929203539823 0.368195911888765 0.600783954443498 GO:0120515 fatty acid-CoA ligase activity 1/339 25/18639 0.04 2.19929203539823 0.368195911888765 0.600783954443498 GO:0015108 chloride transmembrane transporter activity 3/339 121/18639 0.0247933884297521 1.36319754260221 0.37812571157972 0.604711213901104 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/339 26/18639 0.0384615384615385 2.11470388019061 0.379702390123949 0.604711213901104 GO:0004435 phosphatidylinositol phospholipase C activity 1/339 26/18639 0.0384615384615385 2.11470388019061 0.379702390123949 0.604711213901104 GO:0005112 Notch binding 1/339 26/18639 0.0384615384615385 2.11470388019061 0.379702390123949 0.604711213901104 GO:0008143 poly(A) binding 1/339 26/18639 0.0384615384615385 2.11470388019061 0.379702390123949 0.604711213901104 GO:0008198 ferrous iron binding 1/339 26/18639 0.0384615384615385 2.11470388019061 0.379702390123949 0.604711213901104 GO:0015145 monosaccharide transmembrane transporter activity 1/339 26/18639 0.0384615384615385 2.11470388019061 0.379702390123949 0.604711213901104 GO:0030247 polysaccharide binding 1/339 26/18639 0.0384615384615385 2.11470388019061 0.379702390123949 0.604711213901104 GO:0034237 protein kinase A regulatory subunit binding 1/339 26/18639 0.0384615384615385 2.11470388019061 0.379702390123949 0.604711213901104 GO:0050750 low-density lipoprotein particle receptor binding 1/339 26/18639 0.0384615384615385 2.11470388019061 0.379702390123949 0.604711213901104 GO:0070006 metalloaminopeptidase activity 1/339 26/18639 0.0384615384615385 2.11470388019061 0.379702390123949 0.604711213901104 GO:0008017 microtubule binding 6/339 276/18639 0.0217391304347826 1.19526741054252 0.387539163437738 0.612036274499312 GO:0003823 antigen binding 4/339 174/18639 0.0229885057471264 1.26396093988404 0.390089840295176 0.612036274499312 GO:0035064 methylated histone binding 2/339 74/18639 0.027027027027027 1.48600813202583 0.390685148666469 0.612036274499312 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/339 27/18639 0.037037037037037 2.03638151425762 0.390999918182187 0.612036274499312 GO:0005044 scavenger receptor activity 1/339 27/18639 0.037037037037037 2.03638151425762 0.390999918182187 0.612036274499312 GO:0008266 poly(U) RNA binding 1/339 27/18639 0.037037037037037 2.03638151425762 0.390999918182187 0.612036274499312 GO:0015252 proton channel activity 1/339 27/18639 0.037037037037037 2.03638151425762 0.390999918182187 0.612036274499312 GO:0016405 CoA-ligase activity 1/339 27/18639 0.037037037037037 2.03638151425762 0.390999918182187 0.612036274499312 GO:0003725 double-stranded RNA binding 2/339 75/18639 0.0266666666666667 1.46619469026549 0.397110200903052 0.618950014627145 GO:0044183 protein folding chaperone 2/339 75/18639 0.0266666666666667 1.46619469026549 0.397110200903052 0.618950014627145 GO:0005242 inward rectifier potassium channel activity 1/339 28/18639 0.0357142857142857 1.96365360303413 0.402092279440313 0.620104338124195 GO:0046625 sphingolipid binding 1/339 28/18639 0.0357142857142857 1.96365360303413 0.402092279440313 0.620104338124195 GO:0046966 nuclear thyroid hormone receptor binding 1/339 28/18639 0.0357142857142857 1.96365360303413 0.402092279440313 0.620104338124195 GO:0051119 sugar transmembrane transporter activity 1/339 28/18639 0.0357142857142857 1.96365360303413 0.402092279440313 0.620104338124195 GO:0141052 histone H3 demethylase activity 1/339 28/18639 0.0357142857142857 1.96365360303413 0.402092279440313 0.620104338124195 GO:0140034 methylation-dependent protein binding 2/339 76/18639 0.0263157894736842 1.44690265486726 0.403503865358024 0.620971211740453 GO:0005085 guanyl-nucleotide exchange factor activity 5/339 230/18639 0.0217391304347826 1.19526741054252 0.40742124909634 0.622455074510453 GO:0031267 small GTPase binding 6/339 283/18639 0.0212014134275618 1.16570249226055 0.410238612015416 0.622455074510453 GO:0140097 catalytic activity, acting on DNA 7/339 336/18639 0.0208333333333333 1.14546460176991 0.411822635995155 0.622455074510453 GO:0003785 actin monomer binding 1/339 29/18639 0.0344827586206897 1.89594140982606 0.412983188970683 0.622455074510453 GO:0004629 phospholipase C activity 1/339 29/18639 0.0344827586206897 1.89594140982606 0.412983188970683 0.622455074510453 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/339 29/18639 0.0344827586206897 1.89594140982606 0.412983188970683 0.622455074510453 GO:0035250 UDP-galactosyltransferase activity 1/339 29/18639 0.0344827586206897 1.89594140982606 0.412983188970683 0.622455074510453 GO:0097472 cyclin-dependent protein kinase activity 1/339 29/18639 0.0344827586206897 1.89594140982606 0.412983188970683 0.622455074510453 GO:0099604 ligand-gated calcium channel activity 1/339 29/18639 0.0344827586206897 1.89594140982606 0.412983188970683 0.622455074510453 GO:0106222 lncRNA binding 1/339 29/18639 0.0344827586206897 1.89594140982606 0.412983188970683 0.622455074510453 GO:0033293 monocarboxylic acid binding 2/339 79/18639 0.0253164556962025 1.39195698442926 0.42248691942182 0.629486527393102 GO:0015291 secondary active transmembrane transporter activity 6/339 287/18639 0.0209059233449477 1.14945576762974 0.423180078674712 0.629486527393102 GO:0001965 G-protein alpha-subunit binding 1/339 30/18639 0.0333333333333333 1.83274336283186 0.423676294770734 0.629486527393102 GO:0008187 poly-pyrimidine tract binding 1/339 30/18639 0.0333333333333333 1.83274336283186 0.423676294770734 0.629486527393102 GO:0032452 histone demethylase activity 1/339 30/18639 0.0333333333333333 1.83274336283186 0.423676294770734 0.629486527393102 GO:0033612 receptor serine/threonine kinase binding 1/339 30/18639 0.0333333333333333 1.83274336283186 0.423676294770734 0.629486527393102 GO:0048019 receptor antagonist activity 1/339 30/18639 0.0333333333333333 1.83274336283186 0.423676294770734 0.629486527393102 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/339 31/18639 0.032258064516129 1.77362260919212 0.434175178970461 0.639762533296941 GO:0016411 acylglycerol O-acyltransferase activity 1/339 31/18639 0.032258064516129 1.77362260919212 0.434175178970461 0.639762533296941 GO:0016878 acid-thiol ligase activity 1/339 31/18639 0.032258064516129 1.77362260919212 0.434175178970461 0.639762533296941 GO:0140457 protein demethylase activity 1/339 31/18639 0.032258064516129 1.77362260919212 0.434175178970461 0.639762533296941 GO:0015101 organic cation transmembrane transporter activity 2/339 81/18639 0.0246913580246914 1.35758767617175 0.434968507590396 0.639762533296941 GO:0051087 protein-folding chaperone binding 3/339 134/18639 0.0223880597014925 1.23094703473782 0.441401746855153 0.64595891738038 GO:0008378 galactosyltransferase activity 1/339 32/18639 0.03125 1.71819690265487 0.444483359018237 0.64595891738038 GO:0031369 translation initiation factor binding 1/339 32/18639 0.03125 1.71819690265487 0.444483359018237 0.64595891738038 GO:0042910 xenobiotic transmembrane transporter activity 1/339 32/18639 0.03125 1.71819690265487 0.444483359018237 0.64595891738038 GO:0043425 bHLH transcription factor binding 1/339 32/18639 0.03125 1.71819690265487 0.444483359018237 0.64595891738038 GO:0070717 poly-purine tract binding 1/339 32/18639 0.03125 1.71819690265487 0.444483359018237 0.64595891738038 GO:0030165 PDZ domain binding 2/339 83/18639 0.0240963855421687 1.32487472011942 0.447303617396683 0.648767746660666 GO:0004860 protein kinase inhibitor activity 2/339 84/18639 0.0238095238095238 1.30910240202276 0.453414446857536 0.653935935782392 GO:0019956 chemokine binding 1/339 33/18639 0.0303030303030303 1.66613032984714 0.454604288845335 0.653935935782392 GO:0042923 neuropeptide binding 1/339 33/18639 0.0303030303030303 1.66613032984714 0.454604288845335 0.653935935782392 GO:0140416 transcription regulator inhibitor activity 1/339 33/18639 0.0303030303030303 1.66613032984714 0.454604288845335 0.653935935782392 GO:0001664 G protein-coupled receptor binding 6/339 297/18639 0.0202020202020202 1.11075355323143 0.455339796598136 0.653935935782392 GO:0008175 tRNA methyltransferase activity 1/339 34/18639 0.0294117647058824 1.61712649661635 0.464541360009553 0.659378124596084 GO:0015035 protein-disulfide reductase activity 1/339 34/18639 0.0294117647058824 1.61712649661635 0.464541360009553 0.659378124596084 GO:0019825 oxygen binding 1/339 34/18639 0.0294117647058824 1.61712649661635 0.464541360009553 0.659378124596084 GO:0051427 hormone receptor binding 1/339 34/18639 0.0294117647058824 1.61712649661635 0.464541360009553 0.659378124596084 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/339 34/18639 0.0294117647058824 1.61712649661635 0.464541360009553 0.659378124596084 GO:0090482 vitamin transmembrane transporter activity 1/339 34/18639 0.0294117647058824 1.61712649661635 0.464541360009553 0.659378124596084 GO:0008081 phosphoric diester hydrolase activity 2/339 87/18639 0.0229885057471264 1.26396093988404 0.471512312289128 0.667975775742931 GO:0140566 histone reader activity 1/339 35/18639 0.0285714285714286 1.57092288242731 0.474297902818301 0.670622373230518 GO:0004197 cysteine-type endopeptidase activity 2/339 88/18639 0.0227272727272727 1.24959774738536 0.47746478868716 0.672460501924813 GO:0020037 heme binding 3/339 142/18639 0.0211267605633803 1.16159790602019 0.479102531375348 0.672460501924813 GO:0016758 hexosyltransferase activity 4/339 197/18639 0.0203045685279188 1.11639189614123 0.482945544428821 0.672460501924813 GO:0003727 single-stranded RNA binding 2/339 89/18639 0.0224719101123595 1.23555732325743 0.483376307941016 0.672460501924813 GO:0004190 aspartic-type endopeptidase activity 1/339 36/18639 0.0277777777777778 1.52728613569322 0.483877187431534 0.672460501924813 GO:0005484 SNAP receptor activity 1/339 36/18639 0.0277777777777778 1.52728613569322 0.483877187431534 0.672460501924813 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/339 36/18639 0.0277777777777778 1.52728613569322 0.483877187431534 0.672460501924813 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/339 36/18639 0.0277777777777778 1.52728613569322 0.483877187431534 0.672460501924813 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/339 36/18639 0.0277777777777778 1.52728613569322 0.483877187431534 0.672460501924813 GO:0019210 kinase inhibitor activity 2/339 90/18639 0.0222222222222222 1.22182890855457 0.489246387893952 0.678632086433546 GO:0019213 deacetylase activity 1/339 37/18639 0.027027027027027 1.48600813202583 0.493282424944877 0.681643577759367 GO:0070001 aspartic-type peptidase activity 1/339 37/18639 0.027027027027027 1.48600813202583 0.493282424944877 0.681643577759367 GO:0005109 frizzled binding 1/339 38/18639 0.0263157894736842 1.44690265486726 0.5025167684533 0.690488266427373 GO:0005501 retinoid binding 1/339 38/18639 0.0263157894736842 1.44690265486726 0.5025167684533 0.690488266427373 GO:0019840 isoprenoid binding 1/339 38/18639 0.0263157894736842 1.44690265486726 0.5025167684533 0.690488266427373 GO:0051213 dioxygenase activity 2/339 93/18639 0.021505376344086 1.18241507279475 0.506603628834155 0.694296732885065 GO:0008168 methyltransferase activity 4/339 204/18639 0.0196078431372549 1.07808433107756 0.510150663804096 0.694296732885065 GO:0008509 monoatomic anion transmembrane transporter activity 3/339 149/18639 0.0201342281879195 1.10702619231455 0.511090239670332 0.694296732885065 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/339 39/18639 0.0256410256410256 1.40980258679374 0.511583314095703 0.694296732885065 GO:0051020 GTPase binding 6/339 315/18639 0.019047619047619 1.0472819216182 0.512032842276224 0.694296732885065 GO:0016410 N-acyltransferase activity 2/339 94/18639 0.0212765957446809 1.16983618904161 0.512303734681554 0.694296732885065 GO:0004177 aminopeptidase activity 1/339 40/18639 0.025 1.37455752212389 0.520485102080733 0.694296732885065 GO:0015036 disulfide oxidoreductase activity 1/339 40/18639 0.025 1.37455752212389 0.520485102080733 0.694296732885065 GO:0015144 carbohydrate transmembrane transporter activity 1/339 40/18639 0.025 1.37455752212389 0.520485102080733 0.694296732885065 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/339 40/18639 0.025 1.37455752212389 0.520485102080733 0.694296732885065 GO:0030331 nuclear estrogen receptor binding 1/339 40/18639 0.025 1.37455752212389 0.520485102080733 0.694296732885065 GO:0032451 demethylase activity 1/339 40/18639 0.025 1.37455752212389 0.520485102080733 0.694296732885065 GO:0061791 GTPase motor activity 1/339 40/18639 0.025 1.37455752212389 0.520485102080733 0.694296732885065 GO:0071949 FAD binding 1/339 40/18639 0.025 1.37455752212389 0.520485102080733 0.694296732885065 GO:0140662 ATP-dependent protein folding chaperone 1/339 40/18639 0.025 1.37455752212389 0.520485102080733 0.694296732885065 GO:1990606 membrane scission GTPase motor activity 1/339 40/18639 0.025 1.37455752212389 0.520485102080733 0.694296732885065 GO:0046906 tetrapyrrole binding 3/339 152/18639 0.0197368421052632 1.08517699115044 0.524480519646879 0.698352021606319 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/339 41/18639 0.024390243902439 1.34103172890136 0.529225117694187 0.699572443100272 GO:0042287 MHC protein binding 1/339 41/18639 0.024390243902439 1.34103172890136 0.529225117694187 0.699572443100272 GO:0140318 protein transporter activity 1/339 41/18639 0.024390243902439 1.34103172890136 0.529225117694187 0.699572443100272 GO:0140828 metal cation:monoatomic cation antiporter activity 1/339 41/18639 0.024390243902439 1.34103172890136 0.529225117694187 0.699572443100272 GO:0005525 GTP binding 7/339 378/18639 0.0185185185185185 1.01819075712881 0.534054950806198 0.702952652317924 GO:0005249 voltage-gated potassium channel activity 2/339 98/18639 0.0204081632653061 1.12208777316236 0.534667133637163 0.702952652317924 GO:0008170 N-methyltransferase activity 2/339 98/18639 0.0204081632653061 1.12208777316236 0.534667133637163 0.702952652317924 GO:0016859 cis-trans isomerase activity 1/339 42/18639 0.0238095238095238 1.30910240202276 0.537806292288319 0.704545519108891 GO:0042056 chemoattractant activity 1/339 42/18639 0.0238095238095238 1.30910240202276 0.537806292288319 0.704545519108891 GO:0008514 organic anion transmembrane transporter activity 5/339 269/18639 0.0185873605947955 1.02197585288022 0.543060654833847 0.710156240936569 GO:0008200 ion channel inhibitor activity 1/339 43/18639 0.0232558139534884 1.27865816011525 0.546231504253381 0.71048973240075 GO:0008375 acetylglucosaminyltransferase activity 1/339 43/18639 0.0232558139534884 1.27865816011525 0.546231504253381 0.71048973240075 GO:0048156 tau protein binding 1/339 43/18639 0.0232558139534884 1.27865816011525 0.546231504253381 0.71048973240075 GO:0016741 transferase activity, transferring one-carbon groups 4/339 215/18639 0.0186046511627907 1.0229265280922 0.551534427302163 0.716113084117017 GO:0030547 signaling receptor inhibitor activity 1/339 44/18639 0.0227272727272727 1.24959774738536 0.554503579971713 0.717419676034199 GO:0043014 alpha-tubulin binding 1/339 44/18639 0.0227272727272727 1.24959774738536 0.554503579971713 0.717419676034199 GO:0003924 GTPase activity 6/339 331/18639 0.0181268882175227 0.99665802208379 0.560498493598662 0.723894697562937 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/339 45/18639 0.0222222222222222 1.22182890855457 0.562625294754697 0.724082905749443 GO:0046915 transition metal ion transmembrane transporter activity 1/339 45/18639 0.0222222222222222 1.22182890855457 0.562625294754697 0.724082905749443 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/339 46/18639 0.0217391304347826 1.19526741054252 0.57059937376288 0.731768670562571 GO:0030291 protein serine/threonine kinase inhibitor activity 1/339 46/18639 0.0217391304347826 1.19526741054252 0.57059937376288 0.731768670562571 GO:0005504 fatty acid binding 1/339 47/18639 0.0212765957446809 1.16983618904161 0.578428492909569 0.73408199360572 GO:0061733 protein-lysine-acetyltransferase activity 1/339 47/18639 0.0212765957446809 1.16983618904161 0.578428492909569 0.73408199360572 GO:0061749 forked DNA-dependent helicase activity 1/339 47/18639 0.0212765957446809 1.16983618904161 0.578428492909569 0.73408199360572 GO:0099095 ligand-gated monoatomic anion channel activity 1/339 47/18639 0.0212765957446809 1.16983618904161 0.578428492909569 0.73408199360572 GO:0140938 histone H3 methyltransferase activity 1/339 47/18639 0.0212765957446809 1.16983618904161 0.578428492909569 0.73408199360572 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/339 47/18639 0.0212765957446809 1.16983618904161 0.578428492909569 0.73408199360572 GO:0008188 neuropeptide receptor activity 1/339 48/18639 0.0208333333333333 1.14546460176991 0.586115279748191 0.736168847931147 GO:0009378 four-way junction helicase activity 1/339 48/18639 0.0208333333333333 1.14546460176991 0.586115279748191 0.736168847931147 GO:0036121 double-stranded DNA helicase activity 1/339 48/18639 0.0208333333333333 1.14546460176991 0.586115279748191 0.736168847931147 GO:0038187 pattern recognition receptor activity 1/339 48/18639 0.0208333333333333 1.14546460176991 0.586115279748191 0.736168847931147 GO:0043138 3'-5' DNA helicase activity 1/339 48/18639 0.0208333333333333 1.14546460176991 0.586115279748191 0.736168847931147 GO:0140693 molecular condensate scaffold activity 1/339 48/18639 0.0208333333333333 1.14546460176991 0.586115279748191 0.736168847931147 GO:0005496 steroid binding 2/339 108/18639 0.0185185185185185 1.01819075712881 0.58743898921205 0.736326065006135 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 3/339 167/18639 0.0179640718562874 0.987706003921361 0.588255023205996 0.736326065006135 GO:0004620 phospholipase activity 2/339 109/18639 0.018348623853211 1.00884955752212 0.592465993992939 0.739786350270049 GO:0019001 guanyl nucleotide binding 7/339 400/18639 0.0175 0.962190265486726 0.594055523404266 0.739786350270049 GO:0032561 guanyl ribonucleotide binding 7/339 400/18639 0.0175 0.962190265486726 0.594055523404266 0.739786350270049 GO:0015605 organophosphate ester transmembrane transporter activity 1/339 50/18639 0.02 1.09964601769912 0.601072130128409 0.746411977537602 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 4/339 229/18639 0.0174672489082969 0.960389535108397 0.601418132379819 0.746411977537602 GO:0000287 magnesium ion binding 4/339 230/18639 0.0173913043478261 0.956213928434013 0.604851705535279 0.749401011434388 GO:0030544 Hsp70 protein binding 1/339 51/18639 0.0196078431372549 1.07808433107756 0.608347214742238 0.752456538031431 GO:0005544 calcium-dependent phospholipid binding 1/339 53/18639 0.0188679245283019 1.03740190348973 0.622502916992485 0.762227189818269 GO:0008146 sulfotransferase activity 1/339 53/18639 0.0188679245283019 1.03740190348973 0.622502916992485 0.762227189818269 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/339 53/18639 0.0188679245283019 1.03740190348973 0.622502916992485 0.762227189818269 GO:0034212 protein N-acetyltransferase activity 1/339 53/18639 0.0188679245283019 1.03740190348973 0.622502916992485 0.762227189818269 GO:0051018 protein kinase A binding 1/339 53/18639 0.0188679245283019 1.03740190348973 0.622502916992485 0.762227189818269 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/339 53/18639 0.0188679245283019 1.03740190348973 0.622502916992485 0.762227189818269 GO:0043021 ribonucleoprotein complex binding 3/339 177/18639 0.0169491525423729 0.931903404829759 0.627609219541946 0.76425720722261 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 1/339 54/18639 0.0185185185185185 1.01819075712881 0.629388288300973 0.76425720722261 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 1/339 54/18639 0.0185185185185185 1.01819075712881 0.629388288300973 0.76425720722261 GO:0050661 NADP binding 1/339 54/18639 0.0185185185185185 1.01819075712881 0.629388288300973 0.76425720722261 GO:0140463 chromatin-protein adaptor activity 1/339 54/18639 0.0185185185185185 1.01819075712881 0.629388288300973 0.76425720722261 GO:0008374 O-acyltransferase activity 1/339 55/18639 0.0181818181818182 0.999678197908286 0.636148437360213 0.771184921575979 GO:0016853 isomerase activity 3/339 180/18639 0.0166666666666667 0.916371681415929 0.638899787336167 0.77323798765354 GO:0032182 ubiquitin-like protein binding 2/339 120/18639 0.0166666666666667 0.916371681415929 0.644751339584328 0.779030130968832 GO:0003697 single-stranded DNA binding 2/339 121/18639 0.0165289256198347 0.908798361734806 0.649232442576002 0.781943728082583 GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/339 57/18639 0.0175438596491228 0.964601769911504 0.649302110733417 0.781943728082583 GO:0017116 single-stranded DNA helicase activity 1/339 58/18639 0.0172413793103448 0.94797070491303 0.655700054144319 0.788349900624172 GO:1901981 phosphatidylinositol phosphate binding 3/339 185/18639 0.0162162162162162 0.891604879215499 0.657181073515901 0.78883311123173 GO:0015276 ligand-gated monoatomic ion channel activity 3/339 186/18639 0.0161290322580645 0.886811304596061 0.660756601514443 0.791208389117703 GO:0070063 RNA polymerase binding 1/339 59/18639 0.0169491525423729 0.931903404829759 0.661981614966937 0.791208389117703 GO:0005267 potassium channel activity 2/339 124/18639 0.0161290322580645 0.886811304596061 0.662407023447379 0.791208389117703 GO:0031406 carboxylic acid binding 3/339 187/18639 0.0160427807486631 0.88206899815437 0.66430518156724 0.792181219780836 GO:0022834 ligand-gated channel activity 3/339 188/18639 0.0159574468085106 0.877377141781209 0.667826808536913 0.792884494990537 GO:0046943 carboxylic acid transmembrane transporter activity 3/339 188/18639 0.0159574468085106 0.877377141781209 0.667826808536913 0.792884494990537 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/339 60/18639 0.0166666666666667 0.916371681415929 0.668148904123353 0.792884494990537 GO:0005342 organic acid transmembrane transporter activity 3/339 189/18639 0.0158730158730159 0.872734934681837 0.671321482672493 0.794071203614228 GO:0043177 organic acid binding 3/339 189/18639 0.0158730158730159 0.872734934681837 0.671321482672493 0.794071203614228 GO:0019905 syntaxin binding 1/339 61/18639 0.0163934426229508 0.90134919483534 0.674203994359759 0.796192439219683 GO:0015179 L-amino acid transmembrane transporter activity 1/339 62/18639 0.0161290322580645 0.886811304596061 0.68014892093485 0.80191751806996 GO:0005507 copper ion binding 1/339 63/18639 0.0158730158730159 0.872734934681837 0.685985682295839 0.806753916690576 GO:0016298 lipase activity 2/339 130/18639 0.0153846153846154 0.845881552076242 0.687561819559821 0.806753916690576 GO:0016798 hydrolase activity, acting on glycosyl bonds 2/339 130/18639 0.0153846153846154 0.845881552076242 0.687561819559821 0.806753916690576 GO:0005179 hormone activity 2/339 132/18639 0.0151515151515152 0.833065164923572 0.695598453746102 0.814308920719065 GO:0019843 rRNA binding 1/339 65/18639 0.0153846153846154 0.845881552076242 0.69734252307816 0.814308920719065 GO:0160215 deacylase activity 1/339 65/18639 0.0153846153846154 0.845881552076242 0.69734252307816 0.814308920719065 GO:0015631 tubulin binding 6/339 385/18639 0.0155844155844156 0.856867026778531 0.704587198949421 0.821456527004828 GO:0008173 RNA methyltransferase activity 1/339 67/18639 0.0149253731343284 0.820631356491877 0.70828979298469 0.822963838124159 GO:0042054 histone methyltransferase activity 1/339 67/18639 0.0149253731343284 0.820631356491877 0.70828979298469 0.822963838124159 GO:0140098 catalytic activity, acting on RNA 6/339 387/18639 0.0155038759689922 0.852438773410167 0.709257480189084 0.822963838124159 GO:0099094 ligand-gated monoatomic cation channel activity 2/339 136/18639 0.0147058823529412 0.808563248308173 0.711159711309241 0.823863310565856 GO:0003777 microtubule motor activity 1/339 68/18639 0.0147058823529412 0.808563248308173 0.713614462389072 0.824095058461946 GO:0140223 general transcription initiation factor activity 1/339 68/18639 0.0147058823529412 0.808563248308173 0.713614462389072 0.824095058461946 GO:0016757 glycosyltransferase activity 4/339 267/18639 0.0149812734082397 0.823704882171622 0.718701390121703 0.826216451634446 GO:0008080 N-acetyltransferase activity 1/339 69/18639 0.0144927536231884 0.796844940361678 0.718842220573882 0.826216451634446 GO:0016279 protein-lysine N-methyltransferase activity 1/339 69/18639 0.0144927536231884 0.796844940361678 0.718842220573882 0.826216451634446 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/339 70/18639 0.0142857142857143 0.785461441213653 0.723974826240304 0.828209073523728 GO:0016278 lysine N-methyltransferase activity 1/339 70/18639 0.0142857142857143 0.785461441213653 0.723974826240304 0.828209073523728 GO:0016782 transferase activity, transferring sulphur-containing groups 1/339 70/18639 0.0142857142857143 0.785461441213653 0.723974826240304 0.828209073523728 GO:0022843 voltage-gated monoatomic cation channel activity 2/339 143/18639 0.013986013986014 0.76898322916022 0.736790094152647 0.841552435664977 GO:0003678 DNA helicase activity 1/339 74/18639 0.0135135135135135 0.743004066012916 0.743587795921403 0.847991698624876 GO:0015293 symporter activity 2/339 146/18639 0.0136986301369863 0.753182203903503 0.747168906701181 0.850748396882497 GO:0015085 calcium ion transmembrane transporter activity 2/339 147/18639 0.0136054421768707 0.748058515441575 0.75054979627476 0.853268897475661 GO:0015370 solute:sodium symporter activity 1/339 79/18639 0.0126582278481013 0.69597849221463 0.766161292485043 0.869664448457402 GO:0000049 tRNA binding 1/339 80/18639 0.0125 0.687278761061947 0.770432376636313 0.87180505777267 GO:0048306 calcium-dependent protein binding 1/339 80/18639 0.0125 0.687278761061947 0.770432376636313 0.87180505777267 GO:0005506 iron ion binding 2/339 154/18639 0.012987012987013 0.714055855648776 0.77314385585564 0.873521110711705 GO:0005254 chloride channel activity 1/339 83/18639 0.0120481927710843 0.662437360059708 0.782784538922075 0.883048607950674 GO:0051117 ATPase binding 1/339 84/18639 0.0119047619047619 0.654551201011378 0.786752853284298 0.886157682204657 GO:0015079 potassium ion transmembrane transporter activity 2/339 160/18639 0.0125 0.687278761061947 0.791071231553077 0.88965087733123 GO:0042578 phosphoric ester hydrolase activity 5/339 363/18639 0.0137741046831956 0.757331968112338 0.792822850074177 0.890251157302955 GO:0050660 flavin adenine dinucleotide binding 1/339 86/18639 0.0116279069767442 0.639329080057625 0.794473933173333 0.890736879063967 GO:0015081 sodium ion transmembrane transporter activity 2/339 164/18639 0.0121951219512195 0.67051586445068 0.802319434992459 0.898155447135509 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/339 89/18639 0.0112359550561798 0.617778661628716 0.80553602133439 0.899002796328914 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/339 89/18639 0.0112359550561798 0.617778661628716 0.80553602133439 0.899002796328914 GO:0140793 histone H2AXY142 phosphatase activity 1/339 90/18639 0.0111111111111111 0.610914454277286 0.809089837440462 0.901592486538076 GO:0016874 ligase activity 2/339 167/18639 0.0119760479041916 0.658470669280907 0.810400346483398 0.901678315493705 GO:0052689 carboxylic ester hydrolase activity 1/339 92/18639 0.0108695652173913 0.597633705271258 0.816004373258009 0.906533733817028 GO:0005244 voltage-gated monoatomic ion channel activity 2/339 173/18639 0.0115606936416185 0.635633536242263 0.825684834741894 0.914758743864889 GO:0008276 protein methyltransferase activity 1/339 95/18639 0.0105263157894737 0.578761061946903 0.825910767374592 0.914758743864889 GO:0003735 structural constituent of ribosome 2/339 175/18639 0.0114285714285714 0.628369152970923 0.830528739223226 0.916085885842959 GO:0022832 voltage-gated channel activity 2/339 175/18639 0.0114285714285714 0.628369152970923 0.830528739223226 0.916085885842959 GO:0046873 metal ion transmembrane transporter activity 6/339 450/18639 0.0133333333333333 0.733097345132743 0.830868594136637 0.916085885842959 GO:0022836 gated channel activity 4/339 318/18639 0.0125786163522013 0.691601268993154 0.833309341528086 0.917393266049745 GO:0004725 protein tyrosine phosphatase activity 1/339 98/18639 0.0102040816326531 0.561043886581181 0.835285286020365 0.918185780572762 GO:0043130 ubiquitin binding 1/339 100/18639 0.01 0.549823008849558 0.841253604692562 0.923357935480876 GO:0015171 amino acid transmembrane transporter activity 1/339 102/18639 0.00980392156862745 0.539042165538782 0.847006280476007 0.928278247418232 GO:0005253 monoatomic anion channel activity 1/339 103/18639 0.00970873786407767 0.533808746455881 0.849804191190719 0.929950394850922 GO:0008234 cysteine-type peptidase activity 2/339 187/18639 0.0106951871657754 0.58804599876958 0.857127320571447 0.935205549393577 GO:0000149 SNARE binding 1/339 106/18639 0.00943396226415094 0.518700951744866 0.857895501188108 0.935205549393577 GO:0003730 mRNA 3'-UTR binding 3/339 262/18639 0.0114503816793893 0.629568330743768 0.858444491987811 0.935205549393577 GO:1902936 phosphatidylinositol bisphosphate binding 1/339 111/18639 0.00900900900900901 0.49533604400861 0.870426621285584 0.945674546505183 GO:0005261 monoatomic cation channel activity 4/339 341/18639 0.0117302052785924 0.644953676069862 0.870641545551284 0.945674546505183 GO:0016829 lyase activity 2/339 200/18639 0.01 0.549823008849558 0.881603147787297 0.955017048475232 GO:0015294 solute:monoatomic cation symporter activity 1/339 116/18639 0.00862068965517241 0.473985352456515 0.881855687716528 0.955017048475232 GO:0030246 carbohydrate binding 3/339 280/18639 0.0107142857142857 0.58909608091024 0.887018106954835 0.957097710073684 GO:0141003 histone H2AX kinase activity 4/339 354/18639 0.0112994350282486 0.621268936553172 0.888389222803755 0.957097710073684 GO:0140996 histone H3 kinase activity 4/339 357/18639 0.0112044817927171 0.616048189187179 0.892170716472159 0.957097710073684 GO:0004540 RNA nuclease activity 1/339 121/18639 0.00826446280991736 0.454399180867403 0.892279359550528 0.957097710073684 GO:0051082 unfolded protein binding 1/339 121/18639 0.00826446280991736 0.454399180867403 0.892279359550528 0.957097710073684 GO:0008528 G protein-coupled peptide receptor activity 1/339 122/18639 0.00819672131147541 0.45067459741767 0.894251348810295 0.957097710073684 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/339 122/18639 0.00819672131147541 0.45067459741767 0.894251348810295 0.957097710073684 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 1/339 122/18639 0.00819672131147541 0.45067459741767 0.894251348810295 0.957097710073684 GO:0035173 histone kinase activity 4/339 360/18639 0.0111111111111111 0.610914454277286 0.895839846025944 0.957396092755797 GO:0004674 protein serine/threonine kinase activity 5/339 433/18639 0.0115473441108545 0.634899548325124 0.897885626761998 0.958181595858424 GO:0001653 peptide receptor activity 1/339 128/18639 0.0078125 0.429549225663717 0.905349892908489 0.963334456646442 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 1/339 128/18639 0.0078125 0.429549225663717 0.905349892908489 0.963334456646442 GO:0005262 calcium channel activity 1/339 131/18639 0.00763358778625954 0.419712220495845 0.910455619020819 0.96735909520962 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/339 132/18639 0.00757575757575758 0.416532582461786 0.91209575005345 0.967440536702162 GO:0005216 monoatomic ion channel activity 5/339 448/18639 0.0111607142857143 0.613641750948167 0.913179165970577 0.967440536702162 GO:0016779 nucleotidyltransferase activity 1/339 136/18639 0.00735294117647059 0.404281624154086 0.918362136581126 0.970119540232374 GO:0140789 histone phosphatase activity 1/339 136/18639 0.00735294117647059 0.404281624154086 0.918362136581126 0.970119540232374 GO:0140101 catalytic activity, acting on a tRNA 1/339 139/18639 0.00719424460431655 0.395556121474502 0.922767810158714 0.971964364878992 GO:0140767 enzyme-substrate adaptor activity 1/339 139/18639 0.00719424460431655 0.395556121474502 0.922767810158714 0.971964364878992 GO:0019842 vitamin binding 1/339 150/18639 0.00666666666666667 0.366548672566372 0.936988100889443 0.985522736331198 GO:0061630 ubiquitin protein ligase activity 3/339 353/18639 0.0084985835694051 0.467271678908972 0.95708594499377 0.992488995796089 GO:0004721 phosphoprotein phosphatase activity 1/339 175/18639 0.00571428571428571 0.314184576485461 0.960338329100466 0.992488995796089 GO:0016791 phosphatase activity 2/339 273/18639 0.00732600732600733 0.402800739083925 0.960617806315836 0.992488995796089 GO:0106310 protein serine kinase activity 3/339 361/18639 0.00831024930747922 0.456916627852818 0.961577533381594 0.992488995796089 GO:0005319 lipid transporter activity 1/339 178/18639 0.00561797752808989 0.308889330814358 0.962483150769996 0.992488995796089 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1/339 181/18639 0.00552486187845304 0.303769618148927 0.964512308511711 0.992488995796089 GO:0004842 ubiquitin-protein transferase activity 4/339 449/18639 0.0089086859688196 0.489820052427223 0.96491715053098 0.992488995796089 GO:0061659 ubiquitin-like protein ligase activity 3/339 372/18639 0.00806451612903226 0.44340565229803 0.967037508045958 0.992488995796089 GO:0019787 ubiquitin-like protein transferase activity 4/339 479/18639 0.00835073068893528 0.459142387348273 0.976244179850224 0.992488995796089 GO:0004518 nuclease activity 1/339 209/18639 0.00478468899521531 0.263073209975865 0.978889451659702 0.992488995796089 GO:0016755 aminoacyltransferase activity 4/339 496/18639 0.00806451612903226 0.44340565229803 0.981037325313861 0.992488995796089 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 1/339 243/18639 0.00411522633744856 0.226264612695291 0.988776776853379 0.992488995796089 GO:0004676 3-phosphoinositide-dependent protein kinase activity 1/339 245/18639 0.00408163265306122 0.224417554632472 0.989186617911981 0.992488995796089 GO:0004711 ribosomal protein S6 kinase activity 1/339 245/18639 0.00408163265306122 0.224417554632472 0.989186617911981 0.992488995796089 GO:0035175 histone H3S10 kinase activity 1/339 245/18639 0.00408163265306122 0.224417554632472 0.989186617911981 0.992488995796089 GO:0035979 histone H2AXS139 kinase activity 1/339 245/18639 0.00408163265306122 0.224417554632472 0.989186617911981 0.992488995796089 GO:0044022 histone H3S28 kinase activity 1/339 245/18639 0.00408163265306122 0.224417554632472 0.989186617911981 0.992488995796089 GO:0044023 histone H4S1 kinase activity 1/339 245/18639 0.00408163265306122 0.224417554632472 0.989186617911981 0.992488995796089 GO:0044024 histone H2AS1 kinase activity 1/339 245/18639 0.00408163265306122 0.224417554632472 0.989186617911981 0.992488995796089 GO:0044025 histone H2BS14 kinase activity 1/339 245/18639 0.00408163265306122 0.224417554632472 0.989186617911981 0.992488995796089 GO:0072354 histone H3T3 kinase activity 1/339 245/18639 0.00408163265306122 0.224417554632472 0.989186617911981 0.992488995796089 GO:0072371 histone H2AS121 kinase activity 1/339 245/18639 0.00408163265306122 0.224417554632472 0.989186617911981 0.992488995796089 GO:0072518 Rho-dependent protein serine/threonine kinase activity 1/339 245/18639 0.00408163265306122 0.224417554632472 0.989186617911981 0.992488995796089 GO:0140823 histone H2BS36 kinase activity 1/339 245/18639 0.00408163265306122 0.224417554632472 0.989186617911981 0.992488995796089 GO:0140855 histone H3S57 kinase activity 1/339 245/18639 0.00408163265306122 0.224417554632472 0.989186617911981 0.992488995796089 GO:0140995 histone H2A kinase activity 1/339 245/18639 0.00408163265306122 0.224417554632472 0.989186617911981 0.992488995796089 GO:0140997 histone H4 kinase activity 1/339 245/18639 0.00408163265306122 0.224417554632472 0.989186617911981 0.992488995796089 GO:0140998 histone H2B kinase activity 1/339 245/18639 0.00408163265306122 0.224417554632472 0.989186617911981 0.992488995796089 GO:1990244 histone H2AT120 kinase activity 1/339 245/18639 0.00408163265306122 0.224417554632472 0.989186617911981 0.992488995796089 GO:0004677 DNA-dependent protein kinase activity 1/339 246/18639 0.0040650406504065 0.223505288150227 0.98938590770908 0.992488995796089 GO:0140857 histone H3T45 kinase activity 1/339 246/18639 0.0040650406504065 0.223505288150227 0.98938590770908 0.992488995796089 GO:0035402 histone H3T11 kinase activity 1/339 247/18639 0.00404858299595142 0.222600408441116 0.989581535246002 0.992488995796089 GO:0035403 histone H3T6 kinase activity 1/339 247/18639 0.00404858299595142 0.222600408441116 0.989581535246002 0.992488995796089 GO:0004679 AMP-activated protein kinase activity 1/339 248/18639 0.00403225806451613 0.221702826149015 0.989773567627016 0.992488995796089 GO:0030371 translation repressor activity 1/339 329/18639 0.00303951367781155 0.167119455577373 0.997741596621663 0.998636956828959 GO:0045182 translation regulator activity 1/339 356/18639 0.00280898876404494 0.154444665407179 0.998636956828959 0.998636956828959