ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003779 actin binding 51/552 443/18639 0.115124153498871 3.88731720482874 8.30176238232743e-17 7.32215442121279e-14 GO:0045296 cadherin binding 41/552 334/18639 0.122754491017964 4.14496550377506 1.12043166901563e-14 4.94110366035894e-12 GO:0051015 actin filament binding 32/552 209/18639 0.15311004784689 5.1699604743083 2.10670741326875e-14 6.19371979501013e-12 GO:0005201 extracellular matrix structural constituent 27/552 168/18639 0.160714285714286 5.42672748447205 7.16779539069299e-13 1.5804988836478e-10 GO:0019838 growth factor binding 24/552 136/18639 0.176470588235294 5.95875959079284 1.71663182386807e-12 3.02813853730328e-10 GO:0140297 DNA-binding transcription factor binding 41/552 488/18639 0.0840163934426229 2.83692311119031 2.09960148806732e-09 3.08641418745896e-07 GO:0048407 platelet-derived growth factor binding 7/552 11/18639 0.636363636363636 21.4876482213439 5.72816775185065e-09 7.21749136733182e-07 GO:0002020 protease binding 19/552 136/18639 0.139705882352941 4.717351342711 2.03005541987014e-08 2.23813610040683e-06 GO:0005200 structural constituent of cytoskeleton 17/552 112/18639 0.151785714285714 5.1252426242236 3.22549485867329e-08 3.16098496149982e-06 GO:0030020 extracellular matrix structural constituent conferring tensile strength 11/552 44/18639 0.25 8.44157608695652 4.39945286371938e-08 3.88031742580049e-06 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 31/552 349/18639 0.0888252148997135 2.99929924006478 5.78465407334061e-08 4.63824081153311e-06 GO:0097493 structural molecule activity conferring elasticity 6/552 11/18639 0.545454545454545 18.4179841897233 2.67342297125606e-07 1.9649658838732e-05 GO:0005178 integrin binding 19/552 161/18639 0.118012422360248 3.98484337024035 3.12270496735355e-07 2.04207381825721e-05 GO:0098631 cell adhesion mediator activity 13/552 76/18639 0.171052631578947 5.7758152173913 3.24138701310668e-07 2.04207381825721e-05 GO:0044325 transmembrane transporter binding 16/552 136/18639 0.117647058823529 3.97250639386189 2.77318797767314e-06 0.000163063453087181 GO:0008307 structural constituent of muscle 9/552 42/18639 0.214285714285714 7.23563664596273 3.06010410702885e-06 0.000168688238899965 GO:0046332 SMAD binding 12/552 79/18639 0.151898734177215 5.12905888827738 3.39546243456883e-06 0.000176164580428807 GO:0098632 cell-cell adhesion mediator activity 10/552 55/18639 0.181818181818182 6.13932806324111 4.21767328140736e-06 0.000206665990788961 GO:0001223 transcription coactivator binding 9/552 44/18639 0.204545454545455 6.90674407114625 4.6154286869909e-06 0.000214253057996104 GO:0019955 cytokine binding 16/552 144/18639 0.111111111111111 3.7518115942029 5.86876574724027e-06 0.000258812569453296 GO:0001221 transcription coregulator binding 14/552 115/18639 0.121739130434783 4.11068052930057 7.7468749369877e-06 0.000325368747353484 GO:0019199 transmembrane receptor protein kinase activity 11/552 78/18639 0.141025641025641 4.76191471571906 1.79617315236805e-05 0.00072010214563119 GO:0097110 scaffold protein binding 10/552 70/18639 0.142857142857143 4.82375776397516 3.84304720338449e-05 0.00147372505799353 GO:0050431 transforming growth factor beta binding 6/552 24/18639 0.25 8.44157608695652 5.60596543870947e-05 0.00206019229872573 GO:0042805 actinin binding 7/552 37/18639 0.189189189189189 6.38821974148061 9.14711136213273e-05 0.0031029816236158 GO:0043394 proteoglycan binding 7/552 37/18639 0.189189189189189 6.38821974148061 9.14711136213273e-05 0.0031029816236158 GO:0023026 MHC class II protein complex binding 6/552 27/18639 0.222222222222222 7.5036231884058 0.0001143169915432 0.00373435505707786 GO:0005516 calmodulin binding 17/552 207/18639 0.0821256038647343 2.77307813484562 0.000151346691368787 0.00462689090808677 GO:0050840 extracellular matrix binding 9/552 67/18639 0.134328358208955 4.53577222582738 0.000152131333712603 0.00462689090808677 GO:0003712 transcription coregulator activity 30/552 495/18639 0.0606060606060606 2.04644268774704 0.000181586525133372 0.00522969095391517 GO:0008201 heparin binding 15/552 172/18639 0.0872093023255814 2.94473584428716 0.000189919500287889 0.00522969095391517 GO:0002162 dystroglycan binding 4/552 11/18639 0.363636363636364 12.2786561264822 0.000212729516637615 0.00522969095391517 GO:0005114 type II transforming growth factor beta receptor binding 4/552 11/18639 0.363636363636364 12.2786561264822 0.000212729516637615 0.00522969095391517 GO:0048185 activin binding 4/552 11/18639 0.363636363636364 12.2786561264822 0.000212729516637615 0.00522969095391517 GO:0140031 phosphorylation-dependent protein binding 4/552 11/18639 0.363636363636364 12.2786561264822 0.000212729516637615 0.00522969095391517 GO:1901681 sulfur compound binding 20/552 275/18639 0.0727272727272727 2.45573122529644 0.000215182237427257 0.00522969095391517 GO:0016922 nuclear receptor binding 13/552 137/18639 0.0948905109489051 3.20410187242145 0.000219386128452223 0.00522969095391517 GO:0003713 transcription coactivator activity 19/552 256/18639 0.07421875 2.50609290081522 0.000237492445455314 0.00551232465504175 GO:0005518 collagen binding 9/552 72/18639 0.125 4.22078804347826 0.000265700997986293 0.00600893026215154 GO:0051010 microtubule plus-end binding 5/552 21/18639 0.238095238095238 8.03959627329192 0.000307094948809437 0.00670403140254892 GO:0017166 vinculin binding 4/552 12/18639 0.333333333333333 11.2554347826087 0.000311638647964292 0.00670403140254892 GO:0003725 double-stranded RNA binding 9/552 75/18639 0.12 4.05195652173913 0.000362518667703496 0.00761289202177342 GO:0004714 transmembrane receptor protein tyrosine kinase activity 8/552 60/18639 0.133333333333333 4.50217391304348 0.000371159731823015 0.00761309031320697 GO:0005158 insulin receptor binding 5/552 23/18639 0.217391304347826 7.34050094517958 0.000483549990548108 0.00969297935598707 GO:0005161 platelet-derived growth factor receptor binding 4/552 14/18639 0.285714285714286 9.64751552795031 0.000601140717196901 0.0117823580570593 GO:0023023 MHC protein complex binding 6/552 37/18639 0.162162162162162 5.4756169212691 0.00069856931660628 0.0133600494895661 GO:0005021 vascular endothelial growth factor receptor activity 7/552 51/18639 0.137254901960784 4.63459079283887 0.000719418323978953 0.0133600494895661 GO:0042974 nuclear retinoic acid receptor binding 5/552 25/18639 0.2 6.75326086956522 0.00072707752324169 0.0133600494895661 GO:0005160 transforming growth factor beta receptor binding 5/552 26/18639 0.192307692307692 6.49352006688963 0.000878481764522133 0.0158126717613984 GO:0005539 glycosaminoglycan binding 17/552 242/18639 0.0702479338842975 2.37201311534315 0.000921931981077376 0.0162628801462049 GO:0004713 protein tyrosine kinase activity 12/552 140/18639 0.0857142857142857 2.89425465838509 0.000946313480515206 0.0163656566630277 GO:0005159 insulin-like growth factor receptor binding 4/552 16/18639 0.25 8.44157608695652 0.00104268133977962 0.0176854796478005 GO:0045499 chemorepellent activity 5/552 28/18639 0.178571428571429 6.02969720496894 0.00125004162995494 0.0201111224923778 GO:0051393 alpha-actinin binding 5/552 28/18639 0.178571428571429 6.02969720496894 0.00125004162995494 0.0201111224923778 GO:0005096 GTPase activator activity 18/552 271/18639 0.0664206642066421 2.24278036258623 0.00125409494000088 0.0201111224923778 GO:0035615 clathrin adaptor activity 4/552 18/18639 0.222222222222222 7.5036231884058 0.00167256281147634 0.0254344896503816 GO:0098641 cadherin binding involved in cell-cell adhesion 4/552 18/18639 0.222222222222222 7.5036231884058 0.00167256281147634 0.0254344896503816 GO:1990381 ubiquitin-specific protease binding 4/552 18/18639 0.222222222222222 7.5036231884058 0.00167256281147634 0.0254344896503816 GO:0001968 fibronectin binding 5/552 30/18639 0.166666666666667 5.62771739130435 0.00172641767364054 0.0258084811551009 GO:0070325 lipoprotein particle receptor binding 5/552 31/18639 0.161290322580645 5.44617812061711 0.00200896968227894 0.0295318543295004 GO:0017124 SH3 domain binding 10/552 115/18639 0.0869565217391304 2.93620037807183 0.00220966984085337 0.0319496524529947 GO:0032395 MHC class II receptor activity 3/552 10/18639 0.3 10.1298913043478 0.00265350354989258 0.0368112225862253 GO:0070513 death domain binding 3/552 10/18639 0.3 10.1298913043478 0.00265350354989258 0.0368112225862253 GO:0022853 active monoatomic ion transmembrane transporter activity 10/552 118/18639 0.0847457627118644 2.86155121591746 0.00267110912190297 0.0368112225862253 GO:0140312 cargo adaptor activity 4/552 21/18639 0.19047619047619 6.43167701863354 0.00304913983778673 0.041374482106583 GO:0001540 amyloid-beta binding 8/552 83/18639 0.0963855421686747 3.2545835515977 0.00316589062298619 0.0423078110526336 GO:0050998 nitric-oxide synthase binding 3/552 11/18639 0.272727272727273 9.20899209486166 0.0035687938123632 0.0469802409329006 GO:0005010 insulin-like growth factor receptor activity 6/552 51/18639 0.117647058823529 3.97250639386189 0.00381811765635876 0.0488055039551946 GO:0005030 neurotrophin receptor activity 6/552 51/18639 0.117647058823529 3.97250639386189 0.00381811765635876 0.0488055039551946 GO:0015399 primary active transmembrane transporter activity 12/552 166/18639 0.072289156626506 2.44093766369827 0.0039673226472962 0.0499882653559321 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 3/552 12/18639 0.25 8.44157608695652 0.00465451220049616 0.0578208417019383 GO:0017154 semaphorin receptor activity 3/552 13/18639 0.230769230769231 7.79222408026756 0.00591897456291638 0.0686912574275296 GO:0019855 calcium channel inhibitor activity 3/552 13/18639 0.230769230769231 7.79222408026756 0.00591897456291638 0.0686912574275296 GO:0043560 insulin receptor substrate binding 3/552 13/18639 0.230769230769231 7.79222408026756 0.00591897456291638 0.0686912574275296 GO:0051011 microtubule minus-end binding 3/552 13/18639 0.230769230769231 7.79222408026756 0.00591897456291638 0.0686912574275296 GO:0140666 annealing activity 3/552 13/18639 0.230769230769231 7.79222408026756 0.00591897456291638 0.0686912574275296 GO:0051219 phosphoprotein binding 8/552 93/18639 0.0860215053763441 2.90462833099579 0.00633101951712375 0.0725189508325084 GO:0030507 spectrin binding 4/552 26/18639 0.153846153846154 5.19481605351171 0.006777369836626 0.0747205024488017 GO:0050681 nuclear androgen receptor binding 4/552 26/18639 0.153846153846154 5.19481605351171 0.006777369836626 0.0747205024488017 GO:0050750 low-density lipoprotein particle receptor binding 4/552 26/18639 0.153846153846154 5.19481605351171 0.006777369836626 0.0747205024488017 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 5/552 41/18639 0.121951219512195 4.11784199363733 0.0069554282055524 0.0754620034956084 GO:0033218 amide binding 15/552 247/18639 0.0607287449392713 2.05058528428094 0.00701574182158717 0.0754620034956084 GO:0044548 S100 protein binding 3/552 14/18639 0.214285714285714 7.23563664596273 0.00736929288447624 0.0783098352302174 GO:0001786 phosphatidylserine binding 6/552 59/18639 0.101694915254237 3.43386145910096 0.0078371911692369 0.0813223836619641 GO:0004879 nuclear receptor activity 6/552 59/18639 0.101694915254237 3.43386145910096 0.0078371911692369 0.0813223836619641 GO:0003714 transcription corepressor activity 13/552 204/18639 0.0637254901960784 2.15177429667519 0.00793911665623255 0.0814221033813618 GO:0098531 ligand-modulated transcription factor activity 6/552 60/18639 0.1 3.37663043478261 0.00849582759974143 0.0853332999635197 GO:0048156 tau protein binding 5/552 43/18639 0.116279069767442 3.92631445904954 0.00851398004171171 0.0853332999635197 GO:0005523 tropomyosin binding 3/552 15/18639 0.2 6.75326086956522 0.00901145554992243 0.087341799945402 GO:0048531 beta-1,3-galactosyltransferase activity 3/552 15/18639 0.2 6.75326086956522 0.00901145554992243 0.087341799945402 GO:0051371 muscle alpha-actinin binding 3/552 15/18639 0.2 6.75326086956522 0.00901145554992243 0.087341799945402 GO:0016248 channel inhibitor activity 5/552 44/18639 0.113636363636364 3.83708003952569 0.00937717923003026 0.0898986095748553 GO:0141003 histone H2AX kinase activity 19/552 354/18639 0.0536723163841808 1.81231577008106 0.00955313685075563 0.090600717229747 GO:0043236 laminin binding 4/552 29/18639 0.137931034482759 4.65742128935532 0.0100420057848056 0.0940170351147825 GO:0001618 virus receptor activity 7/552 81/18639 0.0864197530864197 2.91807568438003 0.0101265514012521 0.0940170351147825 GO:0141110 transporter inhibitor activity 5/552 45/18639 0.111111111111111 3.7518115942029 0.0102987667990462 0.0944507077367771 GO:0140996 histone H3 kinase activity 19/552 357/18639 0.0532212885154062 1.79708622579467 0.010387436111641 0.0944507077367771 GO:0019903 protein phosphatase binding 10/552 144/18639 0.0694444444444444 2.34488224637681 0.0106968786356374 0.0956550026482374 GO:0140272 exogenous protein binding 7/552 82/18639 0.0853658536585366 2.88248939554613 0.0107977658193742 0.0956550026482374 GO:0005024 transforming growth factor beta receptor activity 3/552 16/18639 0.1875 6.33118206521739 0.0108504034445708 0.0956550026482374 GO:0015631 tubulin binding 20/552 385/18639 0.051948051948052 1.7540937323546 0.011152978627772 0.0956550026482374 GO:0030695 GTPase regulator activity 24/552 489/18639 0.049079754601227 1.65724193118165 0.0112182985991568 0.0956550026482374 GO:0019902 phosphatase binding 12/552 190/18639 0.0631578947368421 2.13260869565217 0.0112383413416927 0.0956550026482374 GO:0035173 histone kinase activity 19/552 360/18639 0.0527777777777778 1.78211050724638 0.0112790479313114 0.0956550026482374 GO:0060589 nucleoside-triphosphatase regulator activity 24/552 490/18639 0.0489795918367347 1.65385980479148 0.0114798070848567 0.09569451785834 GO:0030165 PDZ domain binding 7/552 83/18639 0.0843373493975904 2.84776060764798 0.0115007016927257 0.09569451785834 GO:0043495 protein-membrane adaptor activity 5/552 47/18639 0.106382978723404 3.59216003700278 0.0123241171907205 0.101587582824444 GO:0046965 nuclear retinoid X receptor binding 3/552 17/18639 0.176470588235294 5.95875959079284 0.0128901020813026 0.105269166997304 GO:0005004 GPI-linked ephrin receptor activity 5/552 49/18639 0.102040816326531 3.44554125998225 0.0146034840755083 0.109154855547443 GO:0005008 hepatocyte growth factor receptor activity 5/552 49/18639 0.102040816326531 3.44554125998225 0.0146034840755083 0.109154855547443 GO:0005009 insulin receptor activity 5/552 49/18639 0.102040816326531 3.44554125998225 0.0146034840755083 0.109154855547443 GO:0005011 macrophage colony-stimulating factor receptor activity 5/552 49/18639 0.102040816326531 3.44554125998225 0.0146034840755083 0.109154855547443 GO:0005018 platelet-derived growth factor alpha-receptor activity 5/552 49/18639 0.102040816326531 3.44554125998225 0.0146034840755083 0.109154855547443 GO:0005020 stem cell factor receptor activity 5/552 49/18639 0.102040816326531 3.44554125998225 0.0146034840755083 0.109154855547443 GO:0008288 boss receptor activity 5/552 49/18639 0.102040816326531 3.44554125998225 0.0146034840755083 0.109154855547443 GO:0036332 placental growth factor receptor activity 5/552 49/18639 0.102040816326531 3.44554125998225 0.0146034840755083 0.109154855547443 GO:0038062 protein tyrosine kinase collagen receptor activity 5/552 49/18639 0.102040816326531 3.44554125998225 0.0146034840755083 0.109154855547443 GO:0060175 brain-derived neurotrophic factor receptor activity 5/552 49/18639 0.102040816326531 3.44554125998225 0.0146034840755083 0.109154855547443 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 3/552 18/18639 0.166666666666667 5.62771739130435 0.0151336099352678 0.112141025054041 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 6/552 68/18639 0.0882352941176471 2.97937979539642 0.0152572823202777 0.112141025054041 GO:0005006 epidermal growth factor receptor activity 5/552 50/18639 0.1 3.37663043478261 0.0158423639957063 0.112685201969459 GO:0005007 fibroblast growth factor receptor activity 5/552 50/18639 0.1 3.37663043478261 0.0158423639957063 0.112685201969459 GO:0005017 platelet-derived growth factor receptor activity 5/552 50/18639 0.1 3.37663043478261 0.0158423639957063 0.112685201969459 GO:0005019 platelet-derived growth factor beta-receptor activity 5/552 50/18639 0.1 3.37663043478261 0.0158423639957063 0.112685201969459 GO:0003743 translation initiation factor activity 5/552 51/18639 0.0980392156862745 3.31042199488491 0.0171493472934615 0.121005794502664 GO:0008376 acetylgalactosaminyltransferase activity 4/552 34/18639 0.117647058823529 3.97250639386189 0.0174659456017963 0.12115884583733 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 3/552 19/18639 0.157894736842105 5.33152173913043 0.017583143160066 0.12115884583733 GO:0043395 heparan sulfate proteoglycan binding 3/552 19/18639 0.157894736842105 5.33152173913043 0.017583143160066 0.12115884583733 GO:0140375 immune receptor activity 10/552 156/18639 0.0641025641025641 2.16450668896321 0.0179116141353463 0.121887540033182 GO:0008017 microtubule binding 15/552 276/18639 0.0543478260869565 1.8351252362949 0.0179652836783602 0.121887540033182 GO:0031625 ubiquitin protein ligase binding 16/552 302/18639 0.0529801324503311 1.78894327670602 0.0184289614039923 0.123786217965041 GO:0005080 protein kinase C binding 5/552 52/18639 0.0961538461538462 3.24676003344482 0.0185258285389858 0.123786217965041 GO:0005003 ephrin receptor activity 5/552 53/18639 0.0943396226415094 3.18550041017227 0.0199731321279653 0.130491129902707 GO:0005005 transmembrane-ephrin receptor activity 5/552 53/18639 0.0943396226415094 3.18550041017227 0.0199731321279653 0.130491129902707 GO:0038064 collagen receptor activity 5/552 53/18639 0.0943396226415094 3.18550041017227 0.0199731321279653 0.130491129902707 GO:0035401 histone H3Y41 kinase activity 8/552 115/18639 0.0695652173913043 2.34896030245747 0.0210460210961533 0.135493362093483 GO:0140801 histone H2AXY142 kinase activity 8/552 115/18639 0.0695652173913043 2.34896030245747 0.0210460210961533 0.135493362093483 GO:0042562 hormone binding 7/552 94/18639 0.074468085106383 2.51451202590194 0.0215478048757362 0.137718578988401 GO:0031267 small GTPase binding 15/552 283/18639 0.0530035335689046 1.78973344599785 0.0219426369113899 0.139233134934143 GO:0031491 nucleosome binding 6/552 74/18639 0.0810810810810811 2.73780846063455 0.0222971893837794 0.14047229311781 GO:0008094 ATP-dependent activity, acting on DNA 12/552 210/18639 0.0571428571428571 1.92950310559006 0.0229102798379555 0.143311112177849 GO:0005543 phospholipid binding 23/552 497/18639 0.0462776659959759 1.56262575452716 0.0238249800997347 0.147254887759125 GO:0004896 cytokine receptor activity 7/552 96/18639 0.0729166666666667 2.46212635869565 0.0238746586729647 0.147254887759125 GO:0000146 microfilament motor activity 4/552 38/18639 0.105263157894737 3.55434782608696 0.0253549233939854 0.155298905788161 GO:0051020 GTPase binding 16/552 315/18639 0.0507936507936508 1.71511387163561 0.026044802984085 0.158147948924789 GO:0008093 cytoskeletal anchor activity 3/552 22/18639 0.136363636363636 4.60449604743083 0.0261786854229242 0.158147948924789 GO:0016247 channel regulator activity 10/552 168/18639 0.0595238095238095 2.00989906832298 0.0282010934124989 0.169206560474994 GO:0017134 fibroblast growth factor binding 3/552 23/18639 0.130434782608696 4.40430056710775 0.0294597113972619 0.175563955759358 GO:0015459 potassium channel regulator activity 5/552 59/18639 0.0847457627118644 2.86155121591746 0.0302091562127002 0.176725857747322 GO:0045309 protein phosphorylated amino acid binding 5/552 59/18639 0.0847457627118644 2.86155121591746 0.0302091562127002 0.176725857747322 GO:0141108 transporter regulator activity 10/552 170/18639 0.0588235294117647 1.98625319693095 0.0302557874374666 0.176725857747322 GO:0044389 ubiquitin-like protein ligase binding 16/552 322/18639 0.0496894409937888 1.67782878746962 0.0310145968635325 0.179966279168656 GO:0048306 calcium-dependent protein binding 6/552 80/18639 0.075 2.53247282608696 0.0312505460619312 0.180150206709956 GO:0008137 NADH dehydrogenase (ubiquinone) activity 4/552 41/18639 0.0975609756097561 3.29427359490986 0.0324741691561783 0.182109823538977 GO:0035035 histone acetyltransferase binding 3/552 24/18639 0.125 4.22078804347826 0.0329472408506822 0.182109823538977 GO:0042393 histone binding 13/552 247/18639 0.0526315789473684 1.77717391304348 0.0330206271057403 0.182109823538977 GO:0003680 minor groove of adenine-thymine-rich DNA binding 2/552 10/18639 0.2 6.75326086956522 0.0336552168218291 0.182109823538977 GO:0016303 1-phosphatidylinositol-3-kinase activity 2/552 10/18639 0.2 6.75326086956522 0.0336552168218291 0.182109823538977 GO:0043121 neurotrophin binding 2/552 10/18639 0.2 6.75326086956522 0.0336552168218291 0.182109823538977 GO:0043208 glycosphingolipid binding 2/552 10/18639 0.2 6.75326086956522 0.0336552168218291 0.182109823538977 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 2/552 10/18639 0.2 6.75326086956522 0.0336552168218291 0.182109823538977 GO:0050815 phosphoserine residue binding 2/552 10/18639 0.2 6.75326086956522 0.0336552168218291 0.182109823538977 GO:1990757 ubiquitin ligase activator activity 2/552 10/18639 0.2 6.75326086956522 0.0336552168218291 0.182109823538977 GO:0019905 syntaxin binding 5/552 61/18639 0.0819672131147541 2.76772986457591 0.0342357622101975 0.184069334923621 GO:0042277 peptide binding 13/552 249/18639 0.0522088353413655 1.76289942378208 0.0348954303271653 0.184069334923621 GO:0019894 kinesin binding 4/552 42/18639 0.0952380952380952 3.21583850931677 0.0350812025902137 0.184069334923621 GO:0031492 nucleosomal DNA binding 4/552 42/18639 0.0952380952380952 3.21583850931677 0.0350812025902137 0.184069334923621 GO:0048487 beta-tubulin binding 4/552 42/18639 0.0952380952380952 3.21583850931677 0.0350812025902137 0.184069334923621 GO:0042826 histone deacetylase binding 8/552 127/18639 0.062992125984252 2.12701129750086 0.0352695210908072 0.184069334923621 GO:0003707 nuclear steroid receptor activity 3/552 25/18639 0.12 4.05195652173913 0.0366396125219438 0.189242522857318 GO:0031490 chromatin DNA binding 8/552 128/18639 0.0625 2.11039402173913 0.0366898768805004 0.189242522857318 GO:0008200 ion channel inhibitor activity 4/552 43/18639 0.0930232558139535 3.14105156723964 0.0378060459285216 0.191723842522797 GO:0000149 SNARE binding 7/552 106/18639 0.0660377358490566 2.22985028712059 0.0381075042977427 0.191723842522797 GO:0035591 signaling adaptor activity 8/552 129/18639 0.062015503875969 2.09403437815976 0.0381482459077159 0.191723842522797 GO:0008172 S-methyltransferase activity 2/552 11/18639 0.181818181818182 6.13932806324111 0.0403410886017104 0.191723842522797 GO:0032050 clathrin heavy chain binding 2/552 11/18639 0.181818181818182 6.13932806324111 0.0403410886017104 0.191723842522797 GO:0034713 type I transforming growth factor beta receptor binding 2/552 11/18639 0.181818181818182 6.13932806324111 0.0403410886017104 0.191723842522797 GO:0042608 T cell receptor binding 2/552 11/18639 0.181818181818182 6.13932806324111 0.0403410886017104 0.191723842522797 GO:0045294 alpha-catenin binding 2/552 11/18639 0.181818181818182 6.13932806324111 0.0403410886017104 0.191723842522797 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/552 11/18639 0.181818181818182 6.13932806324111 0.0403410886017104 0.191723842522797 GO:0005112 Notch binding 3/552 26/18639 0.115384615384615 3.89611204013378 0.0405346876548113 0.191723842522797 GO:0008143 poly(A) binding 3/552 26/18639 0.115384615384615 3.89611204013378 0.0405346876548113 0.191723842522797 GO:0030247 polysaccharide binding 3/552 26/18639 0.115384615384615 3.89611204013378 0.0405346876548113 0.191723842522797 GO:0034237 protein kinase A regulatory subunit binding 3/552 26/18639 0.115384615384615 3.89611204013378 0.0405346876548113 0.191723842522797 GO:0043548 phosphatidylinositol 3-kinase binding 3/552 26/18639 0.115384615384615 3.89611204013378 0.0405346876548113 0.191723842522797 GO:0052742 phosphatidylinositol kinase activity 3/552 26/18639 0.115384615384615 3.89611204013378 0.0405346876548113 0.191723842522797 GO:0003954 NADH dehydrogenase activity 4/552 44/18639 0.0909090909090909 3.06966403162055 0.0406489325983707 0.191723842522797 GO:0035091 phosphatidylinositol binding 14/552 284/18639 0.0492957746478873 1.66453612982241 0.0441052103223792 0.206919125023077 GO:0016651 oxidoreductase activity, acting on NAD(P)H 6/552 88/18639 0.0681818181818182 2.30224802371542 0.0464271939867779 0.21256828540042 GO:0030276 clathrin binding 4/552 46/18639 0.0869565217391304 2.93620037807183 0.046688916325629 0.21256828540042 GO:0004000 adenosine deaminase activity 2/552 12/18639 0.166666666666667 5.62771739130435 0.0474784038819532 0.21256828540042 GO:0005078 MAP-kinase scaffold activity 2/552 12/18639 0.166666666666667 5.62771739130435 0.0474784038819532 0.21256828540042 GO:0005095 GTPase inhibitor activity 2/552 12/18639 0.166666666666667 5.62771739130435 0.0474784038819532 0.21256828540042 GO:0035014 phosphatidylinositol 3-kinase regulator activity 2/552 12/18639 0.166666666666667 5.62771739130435 0.0474784038819532 0.21256828540042 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 2/552 12/18639 0.166666666666667 5.62771739130435 0.0474784038819532 0.21256828540042 GO:0140829 bicarbonate:monoatomic anion antiporter activity 2/552 12/18639 0.166666666666667 5.62771739130435 0.0474784038819532 0.21256828540042 GO:0140900 chloride:bicarbonate antiporter activity 2/552 12/18639 0.166666666666667 5.62771739130435 0.0474784038819532 0.21256828540042 GO:0016500 protein-hormone receptor activity 5/552 67/18639 0.0746268656716418 2.51987345879299 0.0482354177896187 0.213611015350485 GO:0003727 single-stranded RNA binding 6/552 89/18639 0.0674157303370786 2.27638006839277 0.048595771251484 0.213611015350485 GO:0099106 ion channel regulator activity 9/552 160/18639 0.05625 1.89935461956522 0.0489006927301973 0.213611015350485 GO:0046875 ephrin receptor binding 3/552 28/18639 0.107142857142857 3.61781832298137 0.0489222506811769 0.213611015350485 GO:0097718 disordered domain specific binding 3/552 28/18639 0.107142857142857 3.61781832298137 0.0489222506811769 0.213611015350485 GO:0072341 modified amino acid binding 6/552 91/18639 0.0659340659340659 2.2263497372193 0.0531175060851588 0.228671056873889 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 4/552 48/18639 0.0833333333333333 2.81385869565217 0.0531996779248184 0.228671056873889 GO:0035250 UDP-galactosyltransferase activity 3/552 29/18639 0.103448275862069 3.49306596701649 0.0534084327846044 0.228671056873889 GO:0106222 lncRNA binding 3/552 29/18639 0.103448275862069 3.49306596701649 0.0534084327846044 0.228671056873889 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 2/552 13/18639 0.153846153846154 5.19481605351171 0.0550346637581417 0.232251547534359 GO:0070123 transforming growth factor beta receptor activity, type III 2/552 13/18639 0.153846153846154 5.19481605351171 0.0550346637581417 0.232251547534359 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 2/552 13/18639 0.153846153846154 5.19481605351171 0.0550346637581417 0.232251547534359 GO:0009055 electron transfer activity 7/552 116/18639 0.0603448275862069 2.03762181409295 0.0570107327026525 0.239445077351141 GO:0035925 mRNA 3'-UTR AU-rich region binding 3/552 30/18639 0.1 3.37663043478261 0.0580847778681518 0.242799877155023 GO:0043539 protein serine/threonine kinase activator activity 5/552 73/18639 0.0684931506849315 2.31276057176891 0.0651637855707794 0.271105938082205 GO:0008378 galactosyltransferase activity 3/552 32/18639 0.09375 3.1655910326087 0.0679918795097753 0.278924826640102 GO:0015106 bicarbonate transmembrane transporter activity 3/552 32/18639 0.09375 3.1655910326087 0.0679918795097753 0.278924826640102 GO:0070717 poly-purine tract binding 3/552 32/18639 0.09375 3.1655910326087 0.0679918795097753 0.278924826640102 GO:0042626 ATPase-coupled transmembrane transporter activity 6/552 98/18639 0.0612244897959184 2.06732475598935 0.0708962995676449 0.286667878214089 GO:0001217 DNA-binding transcription repressor activity 13/552 278/18639 0.0467625899280576 1.57899984360338 0.0711295467008823 0.286667878214089 GO:0005246 calcium channel regulator activity 4/552 53/18639 0.0754716981132075 2.54840032813782 0.0715044594184804 0.286667878214089 GO:0017046 peptide hormone binding 4/552 53/18639 0.0754716981132075 2.54840032813782 0.0715044594184804 0.286667878214089 GO:0051018 protein kinase A binding 4/552 53/18639 0.0754716981132075 2.54840032813782 0.0715044594184804 0.286667878214089 GO:0019956 chemokine binding 3/552 33/18639 0.0909090909090909 3.06966403162055 0.0732139676344489 0.291784374449154 GO:0019209 kinase activator activity 8/552 148/18639 0.0540540540540541 1.82520564042303 0.0734423255416238 0.291784374449154 GO:0017022 myosin binding 5/552 76/18639 0.0657894736842105 2.22146739130435 0.0747244593920536 0.295546964949737 GO:0017069 snRNA binding 4/552 54/18639 0.0740740740740741 2.5012077294686 0.0755054153279448 0.295981228085544 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 4/552 54/18639 0.0740740740740741 2.5012077294686 0.0755054153279448 0.295981228085544 GO:0005521 lamin binding 2/552 16/18639 0.125 4.22078804347826 0.0799145992843091 0.307793347461837 GO:0017070 U6 snRNA binding 2/552 16/18639 0.125 4.22078804347826 0.0799145992843091 0.307793347461837 GO:0070411 I-SMAD binding 2/552 16/18639 0.125 4.22078804347826 0.0799145992843091 0.307793347461837 GO:0097027 ubiquitin-protein transferase activator activity 2/552 16/18639 0.125 4.22078804347826 0.0799145992843091 0.307793347461837 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/552 17/18639 0.117647058823529 3.97250639386189 0.0888511989113767 0.339250032207075 GO:0016805 dipeptidase activity 2/552 17/18639 0.117647058823529 3.97250639386189 0.0888511989113767 0.339250032207075 GO:0005484 SNAP receptor activity 3/552 36/18639 0.0833333333333333 2.81385869565217 0.0898979969632689 0.34176738500691 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 4/552 58/18639 0.0689655172413793 2.32871064467766 0.0925983751952521 0.349024644966719 GO:0061980 regulatory RNA binding 4/552 58/18639 0.0689655172413793 2.32871064467766 0.0925983751952521 0.349024644966719 GO:0004674 protein serine/threonine kinase activity 18/552 433/18639 0.0415704387990762 1.40368008836229 0.0942906706528287 0.353890942620404 GO:0008013 beta-catenin binding 6/552 106/18639 0.0566037735849057 1.91130024610336 0.0949197886363525 0.354742599903656 GO:0140658 ATP-dependent chromatin remodeler activity 8/552 158/18639 0.0506329113924051 1.70968629609246 0.0980149317408537 0.358896770225935 GO:0017075 syntaxin-1 binding 2/552 18/18639 0.111111111111111 3.7518115942029 0.0980658975333903 0.358896770225935 GO:0017128 phospholipid scramblase activity 2/552 18/18639 0.111111111111111 3.7518115942029 0.0980658975333903 0.358896770225935 GO:0034185 apolipoprotein binding 2/552 18/18639 0.111111111111111 3.7518115942029 0.0980658975333903 0.358896770225935 GO:0070064 proline-rich region binding 2/552 18/18639 0.111111111111111 3.7518115942029 0.0980658975333903 0.358896770225935 GO:0008135 translation factor activity, RNA binding 5/552 83/18639 0.0602409638554217 2.03411471974856 0.0997994410298516 0.363731847059211 GO:0005496 steroid binding 6/552 108/18639 0.0555555555555556 1.87590579710145 0.101530231828804 0.368049025890912 GO:0043531 ADP binding 3/552 38/18639 0.0789473684210526 2.66576086956522 0.101818551380252 0.368049025890912 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 12/552 268/18639 0.0447761194029851 1.51192407527579 0.102607499741673 0.369042943475137 GO:0180051 translation factor activity 5/552 84/18639 0.0595238095238095 2.00989906832298 0.103687917180941 0.369042943475137 GO:0015026 coreceptor activity 4/552 61/18639 0.0655737704918033 2.21418389166073 0.106514863095221 0.369042943475137 GO:0005229 intracellularly calcium-gated chloride channel activity 2/552 19/18639 0.105263157894737 3.55434782608696 0.107534456871428 0.369042943475137 GO:0030506 ankyrin binding 2/552 19/18639 0.105263157894737 3.55434782608696 0.107534456871428 0.369042943475137 GO:0141147 intracellularly calcium-gated channel activity 2/552 19/18639 0.105263157894737 3.55434782608696 0.107534456871428 0.369042943475137 GO:0000217 DNA secondary structure binding 3/552 39/18639 0.0769230769230769 2.59740802675585 0.10800245463101 0.369042943475137 GO:0004222 metalloendopeptidase activity 6/552 110/18639 0.0545454545454545 1.84179841897233 0.108376075038919 0.369042943475137 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 11/552 243/18639 0.0452674897119342 1.52851583467525 0.108385360885664 0.369042943475137 GO:0004676 3-phosphoinositide-dependent protein kinase activity 11/552 245/18639 0.0448979591836735 1.51603815439219 0.112972329635246 0.369042943475137 GO:0004711 ribosomal protein S6 kinase activity 11/552 245/18639 0.0448979591836735 1.51603815439219 0.112972329635246 0.369042943475137 GO:0035175 histone H3S10 kinase activity 11/552 245/18639 0.0448979591836735 1.51603815439219 0.112972329635246 0.369042943475137 GO:0035979 histone H2AXS139 kinase activity 11/552 245/18639 0.0448979591836735 1.51603815439219 0.112972329635246 0.369042943475137 GO:0044022 histone H3S28 kinase activity 11/552 245/18639 0.0448979591836735 1.51603815439219 0.112972329635246 0.369042943475137 GO:0044023 histone H4S1 kinase activity 11/552 245/18639 0.0448979591836735 1.51603815439219 0.112972329635246 0.369042943475137 GO:0044024 histone H2AS1 kinase activity 11/552 245/18639 0.0448979591836735 1.51603815439219 0.112972329635246 0.369042943475137 GO:0044025 histone H2BS14 kinase activity 11/552 245/18639 0.0448979591836735 1.51603815439219 0.112972329635246 0.369042943475137 GO:0072354 histone H3T3 kinase activity 11/552 245/18639 0.0448979591836735 1.51603815439219 0.112972329635246 0.369042943475137 GO:0072371 histone H2AS121 kinase activity 11/552 245/18639 0.0448979591836735 1.51603815439219 0.112972329635246 0.369042943475137 GO:0072518 Rho-dependent protein serine/threonine kinase activity 11/552 245/18639 0.0448979591836735 1.51603815439219 0.112972329635246 0.369042943475137 GO:0140823 histone H2BS36 kinase activity 11/552 245/18639 0.0448979591836735 1.51603815439219 0.112972329635246 0.369042943475137 GO:0140855 histone H3S57 kinase activity 11/552 245/18639 0.0448979591836735 1.51603815439219 0.112972329635246 0.369042943475137 GO:0140995 histone H2A kinase activity 11/552 245/18639 0.0448979591836735 1.51603815439219 0.112972329635246 0.369042943475137 GO:0140997 histone H4 kinase activity 11/552 245/18639 0.0448979591836735 1.51603815439219 0.112972329635246 0.369042943475137 GO:0140998 histone H2B kinase activity 11/552 245/18639 0.0448979591836735 1.51603815439219 0.112972329635246 0.369042943475137 GO:1990244 histone H2AT120 kinase activity 11/552 245/18639 0.0448979591836735 1.51603815439219 0.112972329635246 0.369042943475137 GO:0030331 nuclear estrogen receptor binding 3/552 40/18639 0.075 2.53247282608696 0.114328231826008 0.371901592050642 GO:0004677 DNA-dependent protein kinase activity 11/552 246/18639 0.0447154471544715 1.50987539766702 0.115307002697731 0.371901592050642 GO:0140857 histone H3T45 kinase activity 11/552 246/18639 0.0447154471544715 1.50987539766702 0.115307002697731 0.371901592050642 GO:0016887 ATP hydrolysis activity 17/552 417/18639 0.0407673860911271 1.37656396621833 0.115534054673329 0.371901592050642 GO:0016004 phospholipase activator activity 2/552 20/18639 0.1 3.37663043478261 0.117233825762491 0.374671760301226 GO:0035402 histone H3T11 kinase activity 11/552 247/18639 0.0445344129554656 1.50376254180602 0.117669022226122 0.374671760301226 GO:0035403 histone H3T6 kinase activity 11/552 247/18639 0.0445344129554656 1.50376254180602 0.117669022226122 0.374671760301226 GO:0106310 protein serine kinase activity 15/552 361/18639 0.0415512465373961 1.40303203661327 0.118966848161496 0.375613815658015 GO:0030295 protein kinase activator activity 7/552 139/18639 0.0503597122302158 1.70046137003441 0.119242481161275 0.375613815658015 GO:0070851 growth factor receptor binding 7/552 139/18639 0.0503597122302158 1.70046137003441 0.119242481161275 0.375613815658015 GO:0004679 AMP-activated protein kinase activity 11/552 248/18639 0.0443548387096774 1.49769898316971 0.120058294717217 0.376456283030021 GO:0001727 lipid kinase activity 3/552 41/18639 0.0731707317073171 2.4707051961824 0.120790394668363 0.376456283030021 GO:0042169 SH2 domain binding 3/552 41/18639 0.0731707317073171 2.4707051961824 0.120790394668363 0.376456283030021 GO:0035613 RNA stem-loop binding 2/552 21/18639 0.0952380952380952 3.21583850931677 0.12714209131424 0.392839745207201 GO:0035198 miRNA binding 3/552 42/18639 0.0714285714285714 2.41187888198758 0.127383409443605 0.392839745207201 GO:0051879 Hsp90 protein binding 3/552 42/18639 0.0714285714285714 2.41187888198758 0.127383409443605 0.392839745207201 GO:0030414 peptidase inhibitor activity 8/552 169/18639 0.0473372781065089 1.59840493954206 0.129772911293492 0.397260605711423 GO:0022804 active transmembrane transporter activity 18/552 457/18639 0.0393873085339169 1.32996384739796 0.135186516992528 0.397260605711423 GO:0046982 protein heterodimerization activity 15/552 369/18639 0.040650406504065 1.37261399787911 0.135257059966521 0.397260605711423 GO:0061134 peptidase regulator activity 10/552 226/18639 0.0442477876106195 1.49408426317815 0.13526994939142 0.397260605711423 GO:0032931 histone H3K56 acetyltransferase activity 2/552 22/18639 0.0909090909090909 3.06966403162055 0.137238431903372 0.397260605711423 GO:0043992 histone H3K9 acetyltransferase activity 2/552 22/18639 0.0909090909090909 3.06966403162055 0.137238431903372 0.397260605711423 GO:0043993 histone H3K18 acetyltransferase activity 2/552 22/18639 0.0909090909090909 3.06966403162055 0.137238431903372 0.397260605711423 GO:0043994 histone H3K23 acetyltransferase activity 2/552 22/18639 0.0909090909090909 3.06966403162055 0.137238431903372 0.397260605711423 GO:0043999 histone H2AK5 acetyltransferase activity 2/552 22/18639 0.0909090909090909 3.06966403162055 0.137238431903372 0.397260605711423 GO:0044012 histone H2AK9 acetyltransferase activity 2/552 22/18639 0.0909090909090909 3.06966403162055 0.137238431903372 0.397260605711423 GO:0044014 histone H2BK5 acetyltransferase activity 2/552 22/18639 0.0909090909090909 3.06966403162055 0.137238431903372 0.397260605711423 GO:0044015 histone H2BK12 acetyltransferase activity 2/552 22/18639 0.0909090909090909 3.06966403162055 0.137238431903372 0.397260605711423 GO:0044016 histone H3K4 acetyltransferase activity 2/552 22/18639 0.0909090909090909 3.06966403162055 0.137238431903372 0.397260605711423 GO:0044017 histone H3K27 acetyltransferase activity 2/552 22/18639 0.0909090909090909 3.06966403162055 0.137238431903372 0.397260605711423 GO:0044018 histone H3K36 acetyltransferase activity 2/552 22/18639 0.0909090909090909 3.06966403162055 0.137238431903372 0.397260605711423 GO:0046972 histone H4K16 acetyltransferase activity 2/552 22/18639 0.0909090909090909 3.06966403162055 0.137238431903372 0.397260605711423 GO:0140517 protein-RNA adaptor activity 2/552 22/18639 0.0909090909090909 3.06966403162055 0.137238431903372 0.397260605711423 GO:0140908 histone H3K122 acetyltransferase activity 2/552 22/18639 0.0909090909090909 3.06966403162055 0.137238431903372 0.397260605711423 GO:0043178 alcohol binding 5/552 92/18639 0.0543478260869565 1.8351252362949 0.13737469925395 0.397260605711423 GO:0008194 UDP-glycosyltransferase activity 7/552 145/18639 0.0482758620689655 1.63009745127436 0.139646571951362 0.40251070738922 GO:0001046 core promoter sequence-specific DNA binding 3/552 44/18639 0.0681818181818182 2.30224802371542 0.140939719934714 0.403600107085773 GO:0043014 alpha-tubulin binding 3/552 44/18639 0.0681818181818182 2.30224802371542 0.140939719934714 0.403600107085773 GO:0005548 phospholipid transporter activity 4/552 68/18639 0.0588235294117647 1.98625319693095 0.14231776652424 0.406227411243946 GO:0019207 kinase regulator activity 12/552 287/18639 0.0418118466898955 1.41183154067566 0.146404134022441 0.415415955739279 GO:0044013 histone H2B acetyltransferase activity 2/552 23/18639 0.0869565217391304 2.93620037807183 0.147503071951573 0.415415955739279 GO:0099186 structural constituent of postsynapse 2/552 23/18639 0.0869565217391304 2.93620037807183 0.147503071951573 0.415415955739279 GO:0042605 peptide antigen binding 3/552 45/18639 0.0666666666666667 2.25108695652174 0.14789184818836 0.415415955739279 GO:0046915 transition metal ion transmembrane transporter activity 3/552 45/18639 0.0666666666666667 2.25108695652174 0.14789184818836 0.415415955739279 GO:0015108 chloride transmembrane transporter activity 6/552 121/18639 0.0495867768595041 1.67436219906576 0.15002575649314 0.420072118180792 GO:0043021 ribonucleoprotein complex binding 8/552 177/18639 0.0451977401129944 1.52616064848931 0.155812495427622 0.428563090099342 GO:0003730 mRNA 3'-UTR binding 11/552 262/18639 0.0419847328244275 1.41766926651178 0.156300579223344 0.428563090099342 GO:0001091 RNA polymerase II general transcription initiation factor binding 2/552 24/18639 0.0833333333333333 2.81385869565217 0.157917238415291 0.428563090099342 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 2/552 24/18639 0.0833333333333333 2.81385869565217 0.157917238415291 0.428563090099342 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 2/552 24/18639 0.0833333333333333 2.81385869565217 0.157917238415291 0.428563090099342 GO:0030215 semaphorin receptor binding 2/552 24/18639 0.0833333333333333 2.81385869565217 0.157917238415291 0.428563090099342 GO:0043998 histone H2A acetyltransferase activity 2/552 24/18639 0.0833333333333333 2.81385869565217 0.157917238415291 0.428563090099342 GO:0048027 mRNA 5'-UTR binding 2/552 24/18639 0.0833333333333333 2.81385869565217 0.157917238415291 0.428563090099342 GO:0060229 lipase activator activity 2/552 24/18639 0.0833333333333333 2.81385869565217 0.157917238415291 0.428563090099342 GO:0070840 dynein complex binding 2/552 24/18639 0.0833333333333333 2.81385869565217 0.157917238415291 0.428563090099342 GO:0000510 H3-H4 histone complex chaperone activity 7/552 151/18639 0.0463576158940397 1.56532536711777 0.161619940198227 0.430682110269275 GO:0140584 chromatin extrusion motor activity 7/552 151/18639 0.0463576158940397 1.56532536711777 0.161619940198227 0.430682110269275 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 7/552 151/18639 0.0463576158940397 1.56532536711777 0.161619940198227 0.430682110269275 GO:0140849 ATP-dependent H2AZ histone chaperone activity 7/552 151/18639 0.0463576158940397 1.56532536711777 0.161619940198227 0.430682110269275 GO:0001784 phosphotyrosine residue binding 3/552 47/18639 0.0638297872340425 2.15529602220167 0.162116168491383 0.430682110269275 GO:0099095 ligand-gated monoatomic anion channel activity 3/552 47/18639 0.0638297872340425 2.15529602220167 0.162116168491383 0.430682110269275 GO:0140359 ABC-type transporter activity 3/552 47/18639 0.0638297872340425 2.15529602220167 0.162116168491383 0.430682110269275 GO:0015616 DNA translocase activity 7/552 152/18639 0.0460526315789474 1.55502717391304 0.165426425041915 0.436844631398111 GO:0140674 ATP-dependent histone chaperone activity 7/552 152/18639 0.0460526315789474 1.55502717391304 0.165426425041915 0.436844631398111 GO:0015645 fatty acid ligase activity 2/552 25/18639 0.08 2.70130434782609 0.168463118927755 0.437825093101803 GO:0015662 P-type ion transporter activity 2/552 25/18639 0.08 2.70130434782609 0.168463118927755 0.437825093101803 GO:0017025 TBP-class protein binding 2/552 25/18639 0.08 2.70130434782609 0.168463118927755 0.437825093101803 GO:0120515 fatty acid-CoA ligase activity 2/552 25/18639 0.08 2.70130434782609 0.168463118927755 0.437825093101803 GO:0140358 P-type transmembrane transporter activity 2/552 25/18639 0.08 2.70130434782609 0.168463118927755 0.437825093101803 GO:0003774 cytoskeletal motor activity 7/552 153/18639 0.0457516339869281 1.54486359761296 0.169272513319405 0.437825093101803 GO:0061775 cohesin loader activity 7/552 153/18639 0.0457516339869281 1.54486359761296 0.169272513319405 0.437825093101803 GO:0004857 enzyme inhibitor activity 16/552 416/18639 0.0384615384615385 1.29870401337793 0.174092974239169 0.448976617774699 GO:0004112 cyclic-nucleotide phosphodiesterase activity 2/552 26/18639 0.0769230769230769 2.59740802675585 0.179123821533834 0.459265147072214 GO:0005227 calcium-activated cation channel activity 2/552 26/18639 0.0769230769230769 2.59740802675585 0.179123821533834 0.459265147072214 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 6/552 128/18639 0.046875 1.58279551630435 0.179742133356998 0.459514671364847 GO:0015078 proton transmembrane transporter activity 8/552 185/18639 0.0432432432432432 1.46016451233843 0.184121155320432 0.467996711794297 GO:1901981 phosphatidylinositol phosphate binding 8/552 185/18639 0.0432432432432432 1.46016451233843 0.184121155320432 0.467996711794297 GO:0005044 scavenger receptor activity 2/552 27/18639 0.0740740740740741 2.5012077294686 0.189883335960339 0.478506006620055 GO:0005104 fibroblast growth factor receptor binding 2/552 27/18639 0.0740740740740741 2.5012077294686 0.189883335960339 0.478506006620055 GO:0016405 CoA-ligase activity 2/552 27/18639 0.0740740740740741 2.5012077294686 0.189883335960339 0.478506006620055 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 18/552 484/18639 0.0371900826446281 1.25577164929932 0.191623478100821 0.481515406509755 GO:0003724 RNA helicase activity 4/552 77/18639 0.051948051948052 1.7540937323546 0.194139574606988 0.4855758924505 GO:0005126 cytokine receptor binding 11/552 275/18639 0.04 1.35065217391304 0.19434046489232 0.4855758924505 GO:0003689 DNA clamp loader activity 7/552 160/18639 0.04375 1.47727581521739 0.197248790751476 0.491450376957068 GO:0140097 catalytic activity, acting on DNA 13/552 336/18639 0.0386904761904762 1.30643439440994 0.199093693296675 0.491779916097751 GO:0005242 inward rectifier potassium channel activity 2/552 28/18639 0.0714285714285714 2.41187888198758 0.200726496366429 0.491779916097751 GO:0036408 histone H3K14 acetyltransferase activity 2/552 28/18639 0.0714285714285714 2.41187888198758 0.200726496366429 0.491779916097751 GO:0046625 sphingolipid binding 2/552 28/18639 0.0714285714285714 2.41187888198758 0.200726496366429 0.491779916097751 GO:0046966 nuclear thyroid hormone receptor binding 2/552 28/18639 0.0714285714285714 2.41187888198758 0.200726496366429 0.491779916097751 GO:0051019 mitogen-activated protein kinase binding 2/552 28/18639 0.0714285714285714 2.41187888198758 0.200726496366429 0.491779916097751 GO:0004866 endopeptidase inhibitor activity 7/552 161/18639 0.0434782608695652 1.46810018903592 0.20138766155762 0.492033012448257 GO:0008186 ATP-dependent activity, acting on RNA 4/552 79/18639 0.0506329113924051 1.70968629609246 0.206373596289183 0.501436671975371 GO:0033293 monocarboxylic acid binding 4/552 79/18639 0.0506329113924051 1.70968629609246 0.206373596289183 0.501436671975371 GO:0140296 general transcription initiation factor binding 3/552 53/18639 0.0566037735849057 1.91130024610336 0.206953943085702 0.50146532363074 GO:0001216 DNA-binding transcription activator activity 18/552 491/18639 0.0366598778004073 1.23786859116267 0.207922243557443 0.502146962944525 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 2/552 29/18639 0.0689655172413793 2.32871064467766 0.211638945520638 0.502146962944525 GO:0010484 histone H3 acetyltransferase activity 2/552 29/18639 0.0689655172413793 2.32871064467766 0.211638945520638 0.502146962944525 GO:0051861 glycolipid binding 2/552 29/18639 0.0689655172413793 2.32871064467766 0.211638945520638 0.502146962944525 GO:0097472 cyclin-dependent protein kinase activity 2/552 29/18639 0.0689655172413793 2.32871064467766 0.211638945520638 0.502146962944525 GO:0140713 histone chaperone activity 7/552 164/18639 0.0426829268292683 1.44124469777306 0.214001786424831 0.502146962944525 GO:0015485 cholesterol binding 3/552 54/18639 0.0555555555555556 1.87590579710145 0.214686209424394 0.502146962944525 GO:0140789 histone phosphatase activity 6/552 136/18639 0.0441176470588235 1.48968989769821 0.216298547978756 0.502146962944525 GO:0015103 inorganic anion transmembrane transporter activity 7/552 165/18639 0.0424242424242424 1.43250988142292 0.218269829893442 0.502146962944525 GO:0015101 organic cation transmembrane transporter activity 4/552 81/18639 0.0493827160493827 1.66747181964573 0.21882350094451 0.502146962944525 GO:0033192 calmodulin-dependent protein phosphatase activity 4/552 81/18639 0.0493827160493827 1.66747181964573 0.21882350094451 0.502146962944525 GO:0140791 histone H2AXS140 phosphatase activity 4/552 81/18639 0.0493827160493827 1.66747181964573 0.21882350094451 0.502146962944525 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 4/552 81/18639 0.0493827160493827 1.66747181964573 0.21882350094451 0.502146962944525 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 4/552 81/18639 0.0493827160493827 1.66747181964573 0.21882350094451 0.502146962944525 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 4/552 81/18639 0.0493827160493827 1.66747181964573 0.21882350094451 0.502146962944525 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 4/552 81/18639 0.0493827160493827 1.66747181964573 0.21882350094451 0.502146962944525 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 4/552 81/18639 0.0493827160493827 1.66747181964573 0.21882350094451 0.502146962944525 GO:1990439 MAP kinase serine/threonine phosphatase activity 4/552 81/18639 0.0493827160493827 1.66747181964573 0.21882350094451 0.502146962944525 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 2/552 30/18639 0.0666666666666667 2.25108695652174 0.222607100352959 0.502146962944525 GO:0008187 poly-pyrimidine tract binding 2/552 30/18639 0.0666666666666667 2.25108695652174 0.222607100352959 0.502146962944525 GO:0022839 monoatomic ion-gated channel activity 2/552 30/18639 0.0666666666666667 2.25108695652174 0.222607100352959 0.502146962944525 GO:0043995 histone H4K5 acetyltransferase activity 2/552 30/18639 0.0666666666666667 2.25108695652174 0.222607100352959 0.502146962944525 GO:0043996 histone H4K8 acetyltransferase activity 2/552 30/18639 0.0666666666666667 2.25108695652174 0.222607100352959 0.502146962944525 GO:0043997 histone H4K12 acetyltransferase activity 2/552 30/18639 0.0666666666666667 2.25108695652174 0.222607100352959 0.502146962944525 GO:0048019 receptor antagonist activity 2/552 30/18639 0.0666666666666667 2.25108695652174 0.222607100352959 0.502146962944525 GO:0051721 protein phosphatase 2A binding 2/552 30/18639 0.0666666666666667 2.25108695652174 0.222607100352959 0.502146962944525 GO:0098918 structural constituent of synapse 2/552 30/18639 0.0666666666666667 2.25108695652174 0.222607100352959 0.502146962944525 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 4/552 82/18639 0.0487804878048781 1.64713679745493 0.225122862745385 0.50523756982552 GO:0033549 MAP kinase phosphatase activity 4/552 82/18639 0.0487804878048781 1.64713679745493 0.225122862745385 0.50523756982552 GO:0019887 protein kinase regulator activity 10/552 255/18639 0.0392156862745098 1.32416879795396 0.225830370401072 0.505539052522196 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 4/552 83/18639 0.0481927710843374 1.62729177579885 0.2314683524525 0.516848321172418 GO:0005452 solute:inorganic anion antiporter activity 2/552 31/18639 0.0645161290322581 2.17847124824684 0.233618118832163 0.519020606574227 GO:0016878 acid-thiol ligase activity 2/552 31/18639 0.0645161290322581 2.17847124824684 0.233618118832163 0.519020606574227 GO:0017018 myosin phosphatase activity 4/552 84/18639 0.0476190476190476 1.60791925465839 0.237857374216079 0.527111065473823 GO:0005085 guanyl-nucleotide exchange factor activity 9/552 230/18639 0.0391304347826087 1.32129017013233 0.243430910896446 0.531452640561564 GO:0031369 translation initiation factor binding 2/552 32/18639 0.0625 2.11039402173913 0.244659868120323 0.531452640561564 GO:0071813 lipoprotein particle binding 2/552 32/18639 0.0625 2.11039402173913 0.244659868120323 0.531452640561564 GO:0071814 protein-lipid complex binding 2/552 32/18639 0.0625 2.11039402173913 0.244659868120323 0.531452640561564 GO:0140030 modification-dependent protein binding 7/552 173/18639 0.0404624277456647 1.36626664991204 0.253442559882519 0.531452640561564 GO:0036002 pre-mRNA binding 3/552 59/18639 0.0508474576271186 1.71693072955048 0.254151223475026 0.531452640561564 GO:0070888 E-box binding 3/552 59/18639 0.0508474576271186 1.71693072955048 0.254151223475026 0.531452640561564 GO:0019239 deaminase activity 2/552 33/18639 0.0606060606060606 2.04644268774704 0.255720893958121 0.531452640561564 GO:0030296 protein tyrosine kinase activator activity 2/552 33/18639 0.0606060606060606 2.04644268774704 0.255720893958121 0.531452640561564 GO:0140311 protein sequestering activity 2/552 33/18639 0.0606060606060606 2.04644268774704 0.255720893958121 0.531452640561564 GO:0008081 phosphoric diester hydrolase activity 4/552 87/18639 0.0459770114942529 1.55247376311844 0.257259888939736 0.531452640561564 GO:0001094 TFIID-class transcription factor complex binding 1/552 10/18639 0.1 3.37663043478261 0.259700780138361 0.531452640561564 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 1/552 10/18639 0.1 3.37663043478261 0.259700780138361 0.531452640561564 GO:0005131 growth hormone receptor binding 1/552 10/18639 0.1 3.37663043478261 0.259700780138361 0.531452640561564 GO:0005381 iron ion transmembrane transporter activity 1/552 10/18639 0.1 3.37663043478261 0.259700780138361 0.531452640561564 GO:0005522 profilin binding 1/552 10/18639 0.1 3.37663043478261 0.259700780138361 0.531452640561564 GO:0008190 eukaryotic initiation factor 4E binding 1/552 10/18639 0.1 3.37663043478261 0.259700780138361 0.531452640561564 GO:0008239 dipeptidyl-peptidase activity 1/552 10/18639 0.1 3.37663043478261 0.259700780138361 0.531452640561564 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/552 10/18639 0.1 3.37663043478261 0.259700780138361 0.531452640561564 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 1/552 10/18639 0.1 3.37663043478261 0.259700780138361 0.531452640561564 GO:0019531 oxalate transmembrane transporter activity 1/552 10/18639 0.1 3.37663043478261 0.259700780138361 0.531452640561564 GO:0030957 Tat protein binding 1/552 10/18639 0.1 3.37663043478261 0.259700780138361 0.531452640561564 GO:0031956 medium-chain fatty acid-CoA ligase activity 1/552 10/18639 0.1 3.37663043478261 0.259700780138361 0.531452640561564 GO:0035374 chondroitin sulfate binding 1/552 10/18639 0.1 3.37663043478261 0.259700780138361 0.531452640561564 GO:0042975 peroxisome proliferator activated receptor binding 1/552 10/18639 0.1 3.37663043478261 0.259700780138361 0.531452640561564 GO:0045322 unmethylated CpG binding 1/552 10/18639 0.1 3.37663043478261 0.259700780138361 0.531452640561564 GO:0047429 nucleoside triphosphate diphosphatase activity 1/552 10/18639 0.1 3.37663043478261 0.259700780138361 0.531452640561564 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/552 10/18639 0.1 3.37663043478261 0.259700780138361 0.531452640561564 GO:0099122 RNA polymerase II C-terminal domain binding 1/552 10/18639 0.1 3.37663043478261 0.259700780138361 0.531452640561564 GO:0140940 histone H2A methyltransferase activity 1/552 10/18639 0.1 3.37663043478261 0.259700780138361 0.531452640561564 GO:0141109 transporter activator activity 1/552 10/18639 0.1 3.37663043478261 0.259700780138361 0.531452640561564 GO:1905394 retromer complex binding 1/552 10/18639 0.1 3.37663043478261 0.259700780138361 0.531452640561564 GO:1990259 histone H2AQ104 methyltransferase activity 1/552 10/18639 0.1 3.37663043478261 0.259700780138361 0.531452640561564 GO:0019208 phosphatase regulator activity 5/552 117/18639 0.0427350427350427 1.44300445930881 0.266085343202099 0.540940517403089 GO:1990782 protein tyrosine kinase binding 5/552 117/18639 0.0427350427350427 1.44300445930881 0.266085343202099 0.540940517403089 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 2/552 34/18639 0.0588235294117647 1.98625319693095 0.266790391236217 0.540940517403089 GO:0030332 cyclin binding 2/552 34/18639 0.0588235294117647 1.98625319693095 0.266790391236217 0.540940517403089 GO:0010485 histone H4 acetyltransferase activity 2/552 35/18639 0.0571428571428571 1.92950310559006 0.277858175709445 0.549565515211429 GO:0140566 histone reader activity 2/552 35/18639 0.0571428571428571 1.92950310559006 0.277858175709445 0.549565515211429 GO:0008509 monoatomic anion transmembrane transporter activity 6/552 149/18639 0.0402684563758389 1.35971695360374 0.280287685168454 0.549565515211429 GO:0042578 phosphoric ester hydrolase activity 13/552 363/18639 0.0358126721763085 1.20926158821416 0.280929675624609 0.549565515211429 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 1/552 11/18639 0.0909090909090909 3.06966403162055 0.281636749292025 0.549565515211429 GO:0003953 NAD+ nucleosidase activity 1/552 11/18639 0.0909090909090909 3.06966403162055 0.281636749292025 0.549565515211429 GO:0005225 volume-sensitive anion channel activity 1/552 11/18639 0.0909090909090909 3.06966403162055 0.281636749292025 0.549565515211429 GO:0008271 secondary active sulfate transmembrane transporter activity 1/552 11/18639 0.0909090909090909 3.06966403162055 0.281636749292025 0.549565515211429 GO:0008526 phosphatidylinositol transfer activity 1/552 11/18639 0.0909090909090909 3.06966403162055 0.281636749292025 0.549565515211429 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/552 11/18639 0.0909090909090909 3.06966403162055 0.281636749292025 0.549565515211429 GO:0019107 myristoyltransferase activity 1/552 11/18639 0.0909090909090909 3.06966403162055 0.281636749292025 0.549565515211429 GO:0034056 estrogen response element binding 1/552 11/18639 0.0909090909090909 3.06966403162055 0.281636749292025 0.549565515211429 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/552 11/18639 0.0909090909090909 3.06966403162055 0.281636749292025 0.549565515211429 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/552 11/18639 0.0909090909090909 3.06966403162055 0.281636749292025 0.549565515211429 GO:0050786 RAGE receptor binding 1/552 11/18639 0.0909090909090909 3.06966403162055 0.281636749292025 0.549565515211429 GO:0099508 voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/552 11/18639 0.0909090909090909 3.06966403162055 0.281636749292025 0.549565515211429 GO:0140537 transcription regulator activator activity 1/552 11/18639 0.0909090909090909 3.06966403162055 0.281636749292025 0.549565515211429 GO:0032182 ubiquitin-like protein binding 5/552 120/18639 0.0416666666666667 1.40692934782609 0.283160002207577 0.551318149993561 GO:0005507 copper ion binding 3/552 63/18639 0.0476190476190476 1.60791925465839 0.286401005094946 0.552022427175603 GO:1901682 sulfur compound transmembrane transporter activity 3/552 63/18639 0.0476190476190476 1.60791925465839 0.286401005094946 0.552022427175603 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/552 36/18639 0.0555555555555556 1.87590579710145 0.288914656812161 0.552022427175603 GO:0055106 ubiquitin-protein transferase regulator activity 2/552 36/18639 0.0555555555555556 1.87590579710145 0.288914656812161 0.552022427175603 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 2/552 36/18639 0.0555555555555556 1.87590579710145 0.288914656812161 0.552022427175603 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 2/552 36/18639 0.0555555555555556 1.87590579710145 0.288914656812161 0.552022427175603 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 2/552 36/18639 0.0555555555555556 1.87590579710145 0.288914656812161 0.552022427175603 GO:0022829 wide pore channel activity 2/552 37/18639 0.0540540540540541 1.82520564042303 0.299950811534524 0.552022427175603 GO:0038024 cargo receptor activity 3/552 65/18639 0.0461538461538462 1.55844481605351 0.302653273977279 0.552022427175603 GO:0004300 enoyl-CoA hydratase activity 1/552 12/18639 0.0833333333333333 2.81385869565217 0.302923871602032 0.552022427175603 GO:0005025 transforming growth factor beta receptor activity, type I 1/552 12/18639 0.0833333333333333 2.81385869565217 0.302923871602032 0.552022427175603 GO:0005026 transforming growth factor beta receptor activity, type II 1/552 12/18639 0.0833333333333333 2.81385869565217 0.302923871602032 0.552022427175603 GO:0005165 neurotrophin receptor binding 1/552 12/18639 0.0833333333333333 2.81385869565217 0.302923871602032 0.552022427175603 GO:0005247 voltage-gated chloride channel activity 1/552 12/18639 0.0833333333333333 2.81385869565217 0.302923871602032 0.552022427175603 GO:0008179 adenylate cyclase binding 1/552 12/18639 0.0833333333333333 2.81385869565217 0.302923871602032 0.552022427175603 GO:0008504 monoamine transmembrane transporter activity 1/552 12/18639 0.0833333333333333 2.81385869565217 0.302923871602032 0.552022427175603 GO:0015132 prostaglandin transmembrane transporter activity 1/552 12/18639 0.0833333333333333 2.81385869565217 0.302923871602032 0.552022427175603 GO:0015166 polyol transmembrane transporter activity 1/552 12/18639 0.0833333333333333 2.81385869565217 0.302923871602032 0.552022427175603 GO:0015269 calcium-activated potassium channel activity 1/552 12/18639 0.0833333333333333 2.81385869565217 0.302923871602032 0.552022427175603 GO:0016208 AMP binding 1/552 12/18639 0.0833333333333333 2.81385869565217 0.302923871602032 0.552022427175603 GO:0016273 arginine N-methyltransferase activity 1/552 12/18639 0.0833333333333333 2.81385869565217 0.302923871602032 0.552022427175603 GO:0016274 protein-arginine N-methyltransferase activity 1/552 12/18639 0.0833333333333333 2.81385869565217 0.302923871602032 0.552022427175603 GO:0016361 activin receptor activity, type I 1/552 12/18639 0.0833333333333333 2.81385869565217 0.302923871602032 0.552022427175603 GO:0016362 activin receptor activity, type II 1/552 12/18639 0.0833333333333333 2.81385869565217 0.302923871602032 0.552022427175603 GO:0017002 activin receptor activity 1/552 12/18639 0.0833333333333333 2.81385869565217 0.302923871602032 0.552022427175603 GO:0035259 nuclear glucocorticoid receptor binding 1/552 12/18639 0.0833333333333333 2.81385869565217 0.302923871602032 0.552022427175603 GO:0035497 cAMP response element binding 1/552 12/18639 0.0833333333333333 2.81385869565217 0.302923871602032 0.552022427175603 GO:0036009 protein-glutamine N-methyltransferase activity 1/552 12/18639 0.0833333333333333 2.81385869565217 0.302923871602032 0.552022427175603 GO:0070679 inositol 1,4,5 trisphosphate binding 1/552 12/18639 0.0833333333333333 2.81385869565217 0.302923871602032 0.552022427175603 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/552 12/18639 0.0833333333333333 2.81385869565217 0.302923871602032 0.552022427175603 GO:1990247 N6-methyladenosine-containing RNA reader activity 1/552 12/18639 0.0833333333333333 2.81385869565217 0.302923871602032 0.552022427175603 GO:0008237 metallopeptidase activity 7/552 184/18639 0.0380434782608696 1.28458766540643 0.304229296347926 0.552119834112903 GO:0061135 endopeptidase regulator activity 7/552 184/18639 0.0380434782608696 1.28458766540643 0.304229296347926 0.552119834112903 GO:0005501 retinoid binding 2/552 38/18639 0.0526315789473684 1.77717391304348 0.310958159320872 0.561260703215879 GO:0019840 isoprenoid binding 2/552 38/18639 0.0526315789473684 1.77717391304348 0.310958159320872 0.561260703215879 GO:0004386 helicase activity 6/552 155/18639 0.0387096774193548 1.30708274894811 0.311175151782953 0.561260703215879 GO:0015276 ligand-gated monoatomic ion channel activity 7/552 186/18639 0.0376344086021505 1.27077489481066 0.313690158690666 0.564029074169008 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 2/552 39/18639 0.0512820512820513 1.73160535117057 0.321928737952757 0.564029074169008 GO:0022834 ligand-gated channel activity 7/552 188/18639 0.0372340425531915 1.25725601295097 0.323204355361439 0.564029074169008 GO:0140597 protein carrier chaperone 7/552 188/18639 0.0372340425531915 1.25725601295097 0.323204355361439 0.564029074169008 GO:0002161 aminoacyl-tRNA editing activity 1/552 13/18639 0.0769230769230769 2.59740802675585 0.323581305589023 0.564029074169008 GO:0004465 lipoprotein lipase activity 1/552 13/18639 0.0769230769230769 2.59740802675585 0.323581305589023 0.564029074169008 GO:0008253 5'-nucleotidase activity 1/552 13/18639 0.0769230769230769 2.59740802675585 0.323581305589023 0.564029074169008 GO:0030955 potassium ion binding 1/552 13/18639 0.0769230769230769 2.59740802675585 0.323581305589023 0.564029074169008 GO:0031994 insulin-like growth factor I binding 1/552 13/18639 0.0769230769230769 2.59740802675585 0.323581305589023 0.564029074169008 GO:0035325 Toll-like receptor binding 1/552 13/18639 0.0769230769230769 2.59740802675585 0.323581305589023 0.564029074169008 GO:0035673 oligopeptide transmembrane transporter activity 1/552 13/18639 0.0769230769230769 2.59740802675585 0.323581305589023 0.564029074169008 GO:0045159 myosin II binding 1/552 13/18639 0.0769230769230769 2.59740802675585 0.323581305589023 0.564029074169008 GO:0070700 BMP receptor binding 1/552 13/18639 0.0769230769230769 2.59740802675585 0.323581305589023 0.564029074169008 GO:0071714 icosanoid transmembrane transporter activity 1/552 13/18639 0.0769230769230769 2.59740802675585 0.323581305589023 0.564029074169008 GO:0071837 HMG box domain binding 1/552 13/18639 0.0769230769230769 2.59740802675585 0.323581305589023 0.564029074169008 GO:0097157 pre-mRNA intronic binding 1/552 13/18639 0.0769230769230769 2.59740802675585 0.323581305589023 0.564029074169008 GO:0140852 histone ubiquitin ligase activity 1/552 13/18639 0.0769230769230769 2.59740802675585 0.323581305589023 0.564029074169008 GO:0003777 microtubule motor activity 3/552 68/18639 0.0441176470588235 1.48968989769821 0.327098413962796 0.567914962825169 GO:0032934 sterol binding 3/552 68/18639 0.0441176470588235 1.48968989769821 0.327098413962796 0.567914962825169 GO:0004177 aminopeptidase activity 2/552 40/18639 0.05 1.6883152173913 0.332855080380481 0.576774422191717 GO:0005545 1-phosphatidylinositol binding 1/552 14/18639 0.0714285714285714 2.41187888198758 0.343627645077633 0.578956665846144 GO:0008191 metalloendopeptidase inhibitor activity 1/552 14/18639 0.0714285714285714 2.41187888198758 0.343627645077633 0.578956665846144 GO:0008474 palmitoyl-(protein) hydrolase activity 1/552 14/18639 0.0714285714285714 2.41187888198758 0.343627645077633 0.578956665846144 GO:0008559 ABC-type xenobiotic transporter activity 1/552 14/18639 0.0714285714285714 2.41187888198758 0.343627645077633 0.578956665846144 GO:0030983 mismatched DNA binding 1/552 14/18639 0.0714285714285714 2.41187888198758 0.343627645077633 0.578956665846144 GO:0032036 myosin heavy chain binding 1/552 14/18639 0.0714285714285714 2.41187888198758 0.343627645077633 0.578956665846144 GO:0034236 protein kinase A catalytic subunit binding 1/552 14/18639 0.0714285714285714 2.41187888198758 0.343627645077633 0.578956665846144 GO:0071933 Arp2/3 complex binding 1/552 14/18639 0.0714285714285714 2.41187888198758 0.343627645077633 0.578956665846144 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/552 14/18639 0.0714285714285714 2.41187888198758 0.343627645077633 0.578956665846144 GO:0098599 palmitoyl hydrolase activity 1/552 14/18639 0.0714285714285714 2.41187888198758 0.343627645077633 0.578956665846144 GO:0098821 BMP receptor activity 1/552 14/18639 0.0714285714285714 2.41187888198758 0.343627645077633 0.578956665846144 GO:1901474 azole transmembrane transporter activity 1/552 14/18639 0.0714285714285714 2.41187888198758 0.343627645077633 0.578956665846144 GO:1901612 cardiolipin binding 1/552 14/18639 0.0714285714285714 2.41187888198758 0.343627645077633 0.578956665846144 GO:0016877 ligase activity, forming carbon-sulfur bonds 2/552 41/18639 0.0487804878048781 1.64713679745493 0.343730192468281 0.578956665846144 GO:0043130 ubiquitin binding 4/552 100/18639 0.04 1.35065217391304 0.343960649550317 0.578956665846144 GO:0004402 histone acetyltransferase activity 2/552 42/18639 0.0476190476190476 1.60791925465839 0.354547531619516 0.593032195158685 GO:0016859 cis-trans isomerase activity 2/552 42/18639 0.0476190476190476 1.60791925465839 0.354547531619516 0.593032195158685 GO:0008238 exopeptidase activity 4/552 102/18639 0.0392156862745098 1.32416879795396 0.357467386187465 0.593032195158685 GO:0004129 cytochrome-c oxidase activity 1/552 15/18639 0.0666666666666667 2.25108695652174 0.36308093581144 0.593032195158685 GO:0004953 icosanoid receptor activity 1/552 15/18639 0.0666666666666667 2.25108695652174 0.36308093581144 0.593032195158685 GO:0005041 low-density lipoprotein particle receptor activity 1/552 15/18639 0.0666666666666667 2.25108695652174 0.36308093581144 0.593032195158685 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/552 15/18639 0.0666666666666667 2.25108695652174 0.36308093581144 0.593032195158685 GO:0008252 nucleotidase activity 1/552 15/18639 0.0666666666666667 2.25108695652174 0.36308093581144 0.593032195158685 GO:0010181 FMN binding 1/552 15/18639 0.0666666666666667 2.25108695652174 0.36308093581144 0.593032195158685 GO:0015116 sulfate transmembrane transporter activity 1/552 15/18639 0.0666666666666667 2.25108695652174 0.36308093581144 0.593032195158685 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 1/552 15/18639 0.0666666666666667 2.25108695652174 0.36308093581144 0.593032195158685 GO:0017081 chloride channel regulator activity 1/552 15/18639 0.0666666666666667 2.25108695652174 0.36308093581144 0.593032195158685 GO:0030553 cGMP binding 1/552 15/18639 0.0666666666666667 2.25108695652174 0.36308093581144 0.593032195158685 GO:0031005 filamin binding 1/552 15/18639 0.0666666666666667 2.25108695652174 0.36308093581144 0.593032195158685 GO:0045504 dynein heavy chain binding 1/552 15/18639 0.0666666666666667 2.25108695652174 0.36308093581144 0.593032195158685 GO:0120283 protein serine/threonine kinase binding 1/552 15/18639 0.0666666666666667 2.25108695652174 0.36308093581144 0.593032195158685 GO:0004722 protein serine/threonine phosphatase activity 4/552 103/18639 0.0388349514563107 1.31131279020684 0.364220200003273 0.593718345234668 GO:0051087 protein-folding chaperone binding 5/552 134/18639 0.0373134328358209 1.2599367293965 0.364847327797267 0.593718345234668 GO:0016758 hexosyltransferase activity 7/552 197/18639 0.0355329949238579 1.19981792098874 0.366503997103864 0.595315884798542 GO:0035064 methylated histone binding 3/552 74/18639 0.0405405405405405 1.36890423031727 0.375862569502538 0.604825073561014 GO:0030547 signaling receptor inhibitor activity 2/552 44/18639 0.0454545454545455 1.53483201581028 0.37598485607389 0.604825073561014 GO:0099094 ligand-gated monoatomic cation channel activity 5/552 136/18639 0.0367647058823529 1.24140824808184 0.376636464685361 0.604825073561014 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 1/552 16/18639 0.0625 2.11039402173913 0.381958691579915 0.604825073561014 GO:0004708 MAP kinase kinase activity 1/552 16/18639 0.0625 2.11039402173913 0.381958691579915 0.604825073561014 GO:0015378 sodium:chloride symporter activity 1/552 16/18639 0.0625 2.11039402173913 0.381958691579915 0.604825073561014 GO:0015562 efflux transmembrane transporter activity 1/552 16/18639 0.0625 2.11039402173913 0.381958691579915 0.604825073561014 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/552 16/18639 0.0625 2.11039402173913 0.381958691579915 0.604825073561014 GO:0019841 retinol binding 1/552 16/18639 0.0625 2.11039402173913 0.381958691579915 0.604825073561014 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/552 16/18639 0.0625 2.11039402173913 0.381958691579915 0.604825073561014 GO:0034450 ubiquitin-ubiquitin ligase activity 1/552 16/18639 0.0625 2.11039402173913 0.381958691579915 0.604825073561014 GO:0043023 ribosomal large subunit binding 1/552 16/18639 0.0625 2.11039402173913 0.381958691579915 0.604825073561014 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/552 16/18639 0.0625 2.11039402173913 0.381958691579915 0.604825073561014 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/552 16/18639 0.0625 2.11039402173913 0.381958691579915 0.604825073561014 GO:0019003 GDP binding 3/552 75/18639 0.04 1.35065217391304 0.383934242733141 0.606606729393193 GO:0004715 non-membrane spanning protein tyrosine kinase activity 2/552 45/18639 0.0444444444444444 1.50072463768116 0.386593833184846 0.606606729393193 GO:0140303 intramembrane lipid transporter activity 2/552 45/18639 0.0444444444444444 1.50072463768116 0.386593833184846 0.606606729393193 GO:0140034 methylation-dependent protein binding 3/552 76/18639 0.0394736842105263 1.33288043478261 0.391981811229022 0.606606729393193 GO:0140767 enzyme-substrate adaptor activity 5/552 139/18639 0.0359712230215827 1.21461526431029 0.394310060629709 0.606606729393193 GO:0030291 protein serine/threonine kinase inhibitor activity 2/552 46/18639 0.0434782608695652 1.46810018903592 0.397122983881738 0.606606729393193 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/552 17/18639 0.0588235294117647 1.98625319693095 0.400277909871699 0.606606729393193 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/552 17/18639 0.0588235294117647 1.98625319693095 0.400277909871699 0.606606729393193 GO:0004550 nucleoside diphosphate kinase activity 1/552 17/18639 0.0588235294117647 1.98625319693095 0.400277909871699 0.606606729393193 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/552 17/18639 0.0588235294117647 1.98625319693095 0.400277909871699 0.606606729393193 GO:0005092 GDP-dissociation inhibitor activity 1/552 17/18639 0.0588235294117647 1.98625319693095 0.400277909871699 0.606606729393193 GO:0008429 phosphatidylethanolamine binding 1/552 17/18639 0.0588235294117647 1.98625319693095 0.400277909871699 0.606606729393193 GO:0008569 minus-end-directed microtubule motor activity 1/552 17/18639 0.0588235294117647 1.98625319693095 0.400277909871699 0.606606729393193 GO:0015278 intracellularly gated calcium channel activity 1/552 17/18639 0.0588235294117647 1.98625319693095 0.400277909871699 0.606606729393193 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/552 17/18639 0.0588235294117647 1.98625319693095 0.400277909871699 0.606606729393193 GO:0016018 cyclosporin A binding 1/552 17/18639 0.0588235294117647 1.98625319693095 0.400277909871699 0.606606729393193 GO:0019198 transmembrane receptor protein phosphatase activity 1/552 17/18639 0.0588235294117647 1.98625319693095 0.400277909871699 0.606606729393193 GO:0030169 low-density lipoprotein particle binding 1/552 17/18639 0.0588235294117647 1.98625319693095 0.400277909871699 0.606606729393193 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/552 17/18639 0.0588235294117647 1.98625319693095 0.400277909871699 0.606606729393193 GO:0032183 SUMO binding 1/552 17/18639 0.0588235294117647 1.98625319693095 0.400277909871699 0.606606729393193 GO:0036041 long-chain fatty acid binding 1/552 17/18639 0.0588235294117647 1.98625319693095 0.400277909871699 0.606606729393193 GO:0038191 neuropilin binding 1/552 17/18639 0.0588235294117647 1.98625319693095 0.400277909871699 0.606606729393193 GO:0070403 NAD+ binding 1/552 17/18639 0.0588235294117647 1.98625319693095 0.400277909871699 0.606606729393193 GO:0070492 oligosaccharide binding 1/552 17/18639 0.0588235294117647 1.98625319693095 0.400277909871699 0.606606729393193 GO:1990226 histone methyltransferase binding 1/552 17/18639 0.0588235294117647 1.98625319693095 0.400277909871699 0.606606729393193 GO:0005504 fatty acid binding 2/552 47/18639 0.0425531914893617 1.43686401480111 0.407567731232421 0.615538936553073 GO:0061733 protein-lysine-acetyltransferase activity 2/552 47/18639 0.0425531914893617 1.43686401480111 0.407567731232421 0.615538936553073 GO:0003823 antigen binding 6/552 174/18639 0.0344827586206897 1.16435532233883 0.411371783547033 0.615566922861499 GO:0004721 phosphoprotein phosphatase activity 6/552 175/18639 0.0342857142857143 1.15770186335404 0.416657449370985 0.615566922861499 GO:1902936 phosphatidylinositol bisphosphate binding 4/552 111/18639 0.036036036036036 1.21680376028202 0.417974149125653 0.615566922861499 GO:0000400 four-way junction DNA binding 1/552 18/18639 0.0555555555555556 1.87590579710145 0.41805508706807 0.615566922861499 GO:0000900 mRNA regulatory element binding translation repressor activity 1/552 18/18639 0.0555555555555556 1.87590579710145 0.41805508706807 0.615566922861499 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/552 18/18639 0.0555555555555556 1.87590579710145 0.41805508706807 0.615566922861499 GO:0004706 JUN kinase kinase kinase activity 1/552 18/18639 0.0555555555555556 1.87590579710145 0.41805508706807 0.615566922861499 GO:0008308 voltage-gated monoatomic anion channel activity 1/552 18/18639 0.0555555555555556 1.87590579710145 0.41805508706807 0.615566922861499 GO:0008525 phosphatidylcholine transporter activity 1/552 18/18639 0.0555555555555556 1.87590579710145 0.41805508706807 0.615566922861499 GO:0015373 monoatomic anion:sodium symporter activity 1/552 18/18639 0.0555555555555556 1.87590579710145 0.41805508706807 0.615566922861499 GO:0030228 lipoprotein particle receptor activity 1/552 18/18639 0.0555555555555556 1.87590579710145 0.41805508706807 0.615566922861499 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/552 18/18639 0.0555555555555556 1.87590579710145 0.41805508706807 0.615566922861499 GO:0050811 GABA receptor binding 1/552 18/18639 0.0555555555555556 1.87590579710145 0.41805508706807 0.615566922861499 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/552 18/18639 0.0555555555555556 1.87590579710145 0.41805508706807 0.615566922861499 GO:1901611 phosphatidylglycerol binding 1/552 18/18639 0.0555555555555556 1.87590579710145 0.41805508706807 0.615566922861499 GO:0016791 phosphatase activity 9/552 273/18639 0.032967032967033 1.11317486860965 0.419538236607808 0.616721207813478 GO:0004252 serine-type endopeptidase activity 6/552 176/18639 0.0340909090909091 1.15112401185771 0.421937676089074 0.619216356589955 GO:0001222 transcription corepressor binding 2/552 49/18639 0.0408163265306122 1.3782165039929 0.428187392258036 0.627344318889681 GO:0005319 lipid transporter activity 6/552 178/18639 0.0337078651685393 1.13819003419638 0.432478287715981 0.628379865259694 GO:0005520 insulin-like growth factor binding 1/552 19/18639 0.0526315789473684 1.77717391304348 0.435306233190105 0.628379865259694 GO:0008574 plus-end-directed microtubule motor activity 1/552 19/18639 0.0526315789473684 1.77717391304348 0.435306233190105 0.628379865259694 GO:0016918 retinal binding 1/552 19/18639 0.0526315789473684 1.77717391304348 0.435306233190105 0.628379865259694 GO:0031420 alkali metal ion binding 1/552 19/18639 0.0526315789473684 1.77717391304348 0.435306233190105 0.628379865259694 GO:0034987 immunoglobulin receptor binding 1/552 19/18639 0.0526315789473684 1.77717391304348 0.435306233190105 0.628379865259694 GO:0042834 peptidoglycan binding 1/552 19/18639 0.0526315789473684 1.77717391304348 0.435306233190105 0.628379865259694 GO:0046624 sphingolipid transporter activity 1/552 19/18639 0.0526315789473684 1.77717391304348 0.435306233190105 0.628379865259694 GO:0097001 ceramide binding 1/552 19/18639 0.0526315789473684 1.77717391304348 0.435306233190105 0.628379865259694 GO:0005254 chloride channel activity 3/552 83/18639 0.036144578313253 1.22046883184914 0.447414960548953 0.643073151031489 GO:0030246 carbohydrate binding 9/552 280/18639 0.0321428571428571 1.08534549689441 0.449064685526412 0.643073151031489 GO:0001972 retinoic acid binding 1/552 20/18639 0.05 1.6883152173913 0.452046886212611 0.643073151031489 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 1/552 20/18639 0.05 1.6883152173913 0.452046886212611 0.643073151031489 GO:0005326 neurotransmitter transmembrane transporter activity 1/552 20/18639 0.05 1.6883152173913 0.452046886212611 0.643073151031489 GO:0043024 ribosomal small subunit binding 1/552 20/18639 0.05 1.6883152173913 0.452046886212611 0.643073151031489 GO:0052745 inositol phosphate phosphatase activity 1/552 20/18639 0.05 1.6883152173913 0.452046886212611 0.643073151031489 GO:0140664 ATP-dependent DNA damage sensor activity 1/552 20/18639 0.05 1.6883152173913 0.452046886212611 0.643073151031489 GO:0140939 histone H4 methyltransferase activity 1/552 20/18639 0.05 1.6883152173913 0.452046886212611 0.643073151031489 GO:0004860 protein kinase inhibitor activity 3/552 84/18639 0.0357142857142857 1.20593944099379 0.455176352635356 0.646482355916883 GO:0030159 signaling receptor complex adaptor activity 2/552 52/18639 0.0384615384615385 1.29870401337793 0.458388145854726 0.649997338655737 GO:0004864 protein phosphatase inhibitor activity 2/552 53/18639 0.0377358490566038 1.27420016406891 0.468248310669197 0.654569976378037 GO:0005544 calcium-dependent phospholipid binding 2/552 53/18639 0.0377358490566038 1.27420016406891 0.468248310669197 0.654569976378037 GO:0034212 protein N-acetyltransferase activity 2/552 53/18639 0.0377358490566038 1.27420016406891 0.468248310669197 0.654569976378037 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/552 21/18639 0.0476190476190476 1.60791925465839 0.46829212595753 0.654569976378037 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/552 21/18639 0.0476190476190476 1.60791925465839 0.46829212595753 0.654569976378037 GO:0005123 death receptor binding 1/552 21/18639 0.0476190476190476 1.60791925465839 0.46829212595753 0.654569976378037 GO:0010314 phosphatidylinositol-5-phosphate binding 1/552 21/18639 0.0476190476190476 1.60791925465839 0.46829212595753 0.654569976378037 GO:0036122 BMP binding 1/552 21/18639 0.0476190476190476 1.60791925465839 0.46829212595753 0.654569976378037 GO:0061891 calcium ion sensor activity 1/552 21/18639 0.0476190476190476 1.60791925465839 0.46829212595753 0.654569976378037 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 3/552 86/18639 0.0348837209302326 1.17789433771486 0.470559374139566 0.656698367074521 GO:0003925 G protein activity 2/552 54/18639 0.037037037037037 1.2506038647343 0.478000699178613 0.658854799760519 GO:0050661 NADP binding 2/552 54/18639 0.037037037037037 1.2506038647343 0.478000699178613 0.658854799760519 GO:0051287 NAD binding 2/552 54/18639 0.037037037037037 1.2506038647343 0.478000699178613 0.658854799760519 GO:0140463 chromatin-protein adaptor activity 2/552 54/18639 0.037037037037037 1.2506038647343 0.478000699178613 0.658854799760519 GO:0003697 single-stranded DNA binding 4/552 121/18639 0.0330578512396694 1.11624146604384 0.483521022424744 0.658854799760519 GO:0004407 histone deacetylase activity 1/552 22/18639 0.0454545454545455 1.53483201581028 0.484056587579157 0.658854799760519 GO:0005243 gap junction channel activity 1/552 22/18639 0.0454545454545455 1.53483201581028 0.484056587579157 0.658854799760519 GO:0008970 phospholipase A1 activity 1/552 22/18639 0.0454545454545455 1.53483201581028 0.484056587579157 0.658854799760519 GO:0015377 chloride:monoatomic cation symporter activity 1/552 22/18639 0.0454545454545455 1.53483201581028 0.484056587579157 0.658854799760519 GO:0033558 protein lysine deacetylase activity 1/552 22/18639 0.0454545454545455 1.53483201581028 0.484056587579157 0.658854799760519 GO:0034062 5'-3' RNA polymerase activity 1/552 22/18639 0.0454545454545455 1.53483201581028 0.484056587579157 0.658854799760519 GO:0050321 tau-protein kinase activity 1/552 22/18639 0.0454545454545455 1.53483201581028 0.484056587579157 0.658854799760519 GO:0070034 telomerase RNA binding 1/552 22/18639 0.0454545454545455 1.53483201581028 0.484056587579157 0.658854799760519 GO:0097747 RNA polymerase activity 1/552 22/18639 0.0454545454545455 1.53483201581028 0.484056587579157 0.658854799760519 GO:0140035 ubiquitin-like protein reader activity 1/552 22/18639 0.0454545454545455 1.53483201581028 0.484056587579157 0.658854799760519 GO:0140784 metal ion sensor activity 1/552 22/18639 0.0454545454545455 1.53483201581028 0.484056587579157 0.658854799760519 GO:0140313 molecular sequestering activity 2/552 55/18639 0.0363636363636364 1.22786561264822 0.487643039720473 0.662713653364341 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 4/552 122/18639 0.0327868852459016 1.10709194583036 0.489923159563551 0.664788041130849 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 3/552 89/18639 0.0337078651685393 1.13819003419638 0.493256741659072 0.667258352980524 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 3/552 89/18639 0.0337078651685393 1.13819003419638 0.493256741659072 0.667258352980524 GO:0019212 phosphatase inhibitor activity 2/552 56/18639 0.0357142857142857 1.20593944099379 0.497173289072021 0.671171399283391 GO:0042171 lysophosphatidic acid acyltransferase activity 1/552 23/18639 0.0434782608695652 1.46810018903592 0.499354474653138 0.671171399283391 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/552 23/18639 0.0434782608695652 1.46810018903592 0.499354474653138 0.671171399283391 GO:0071617 lysophospholipid acyltransferase activity 1/552 23/18639 0.0434782608695652 1.46810018903592 0.499354474653138 0.671171399283391 GO:0019210 kinase inhibitor activity 3/552 90/18639 0.0333333333333333 1.12554347826087 0.500715170893958 0.671171399283391 GO:0140793 histone H2AXY142 phosphatase activity 3/552 90/18639 0.0333333333333333 1.12554347826087 0.500715170893958 0.671171399283391 GO:0016504 peptidase activator activity 2/552 57/18639 0.0350877192982456 1.18478260869565 0.506589620956159 0.678015243829032 GO:0004806 triacylglycerol lipase activity 1/552 24/18639 0.0416666666666667 1.40692934782609 0.51419957188087 0.68096700059899 GO:0015149 hexose transmembrane transporter activity 1/552 24/18639 0.0416666666666667 1.40692934782609 0.51419957188087 0.68096700059899 GO:0019957 C-C chemokine binding 1/552 24/18639 0.0416666666666667 1.40692934782609 0.51419957188087 0.68096700059899 GO:0055056 D-glucose transmembrane transporter activity 1/552 24/18639 0.0416666666666667 1.40692934782609 0.51419957188087 0.68096700059899 GO:0070300 phosphatidic acid binding 1/552 24/18639 0.0416666666666667 1.40692934782609 0.51419957188087 0.68096700059899 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/552 24/18639 0.0416666666666667 1.40692934782609 0.51419957188087 0.68096700059899 GO:0140612 DNA damage sensor activity 1/552 24/18639 0.0416666666666667 1.40692934782609 0.51419957188087 0.68096700059899 GO:0008236 serine-type peptidase activity 6/552 194/18639 0.0309278350515464 1.04431869116988 0.515110436483521 0.681150532201597 GO:0070063 RNA polymerase binding 2/552 59/18639 0.0338983050847458 1.14462048636699 0.525074246308249 0.691735663271445 GO:0008083 growth factor activity 5/552 162/18639 0.0308641975308642 1.04216988727858 0.526124846113331 0.691735663271445 GO:0004709 MAP kinase kinase kinase activity 1/552 25/18639 0.04 1.35065217391304 0.528605257420583 0.691735663271445 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/552 25/18639 0.04 1.35065217391304 0.528605257420583 0.691735663271445 GO:0019211 phosphatase activator activity 1/552 25/18639 0.04 1.35065217391304 0.528605257420583 0.691735663271445 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/552 25/18639 0.04 1.35065217391304 0.528605257420583 0.691735663271445 GO:0019707 protein-cysteine S-acyltransferase activity 1/552 25/18639 0.04 1.35065217391304 0.528605257420583 0.691735663271445 GO:0016410 N-acyltransferase activity 3/552 94/18639 0.0319148936170213 1.07764801110083 0.529972500108016 0.692497400141141 GO:0001098 basal transcription machinery binding 2/552 60/18639 0.0333333333333333 1.12554347826087 0.534139875092784 0.695880900785577 GO:0001099 basal RNA polymerase II transcription machinery binding 2/552 60/18639 0.0333333333333333 1.12554347826087 0.534139875092784 0.695880900785577 GO:0017171 serine hydrolase activity 6/552 198/18639 0.0303030303030303 1.02322134387352 0.53508458041397 0.696083480715519 GO:0004867 serine-type endopeptidase inhibitor activity 3/552 95/18639 0.0315789473684211 1.06630434782609 0.537136216335819 0.697608661957783 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 4/552 130/18639 0.0307692307692308 1.03896321070234 0.539867152478592 0.697608661957783 GO:0004435 phosphatidylinositol phospholipase C activity 1/552 26/18639 0.0384615384615385 1.29870401337793 0.542584514856053 0.697608661957783 GO:0015145 monosaccharide transmembrane transporter activity 1/552 26/18639 0.0384615384615385 1.29870401337793 0.542584514856053 0.697608661957783 GO:0051139 metal cation:proton antiporter activity 1/552 26/18639 0.0384615384615385 1.29870401337793 0.542584514856053 0.697608661957783 GO:0070006 metalloaminopeptidase activity 1/552 26/18639 0.0384615384615385 1.29870401337793 0.542584514856053 0.697608661957783 GO:0097602 cullin family protein binding 1/552 26/18639 0.0384615384615385 1.29870401337793 0.542584514856053 0.697608661957783 GO:0120014 phospholipid transfer activity 1/552 26/18639 0.0384615384615385 1.29870401337793 0.542584514856053 0.697608661957783 GO:0031072 heat shock protein binding 4/552 131/18639 0.0305343511450382 1.03103219382675 0.545936027704632 0.700896035568393 GO:0015179 L-amino acid transmembrane transporter activity 2/552 62/18639 0.032258064516129 1.08923562412342 0.551912434921597 0.703765066464244 GO:0005179 hormone activity 4/552 132/18639 0.0303030303030303 1.02322134387352 0.551963238436487 0.703765066464244 GO:0016874 ligase activity 5/552 167/18639 0.029940119760479 1.0109671960427 0.553205382050488 0.703765066464244 GO:0004364 glutathione transferase activity 1/552 27/18639 0.037037037037037 1.2506038647343 0.556149944813581 0.703765066464244 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/552 27/18639 0.037037037037037 1.2506038647343 0.556149944813581 0.703765066464244 GO:0005385 zinc ion transmembrane transporter activity 1/552 27/18639 0.037037037037037 1.2506038647343 0.556149944813581 0.703765066464244 GO:0008266 poly(U) RNA binding 1/552 27/18639 0.037037037037037 1.2506038647343 0.556149944813581 0.703765066464244 GO:0015252 proton channel activity 1/552 27/18639 0.037037037037037 1.2506038647343 0.556149944813581 0.703765066464244 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/552 27/18639 0.037037037037037 1.2506038647343 0.556149944813581 0.703765066464244 GO:0035255 ionotropic glutamate receptor binding 1/552 27/18639 0.037037037037037 1.2506038647343 0.556149944813581 0.703765066464244 GO:0004725 protein tyrosine phosphatase activity 3/552 98/18639 0.0306122448979592 1.03366237799468 0.558247752910933 0.704398452170877 GO:0005249 voltage-gated potassium channel activity 3/552 98/18639 0.0306122448979592 1.03366237799468 0.558247752910933 0.704398452170877 GO:0050698 proteoglycan sulfotransferase activity 1/552 28/18639 0.0357142857142857 1.20593944099379 0.569313776237549 0.71325958897943 GO:0051119 sugar transmembrane transporter activity 1/552 28/18639 0.0357142857142857 1.20593944099379 0.569313776237549 0.71325958897943 GO:0051959 dynein light intermediate chain binding 1/552 28/18639 0.0357142857142857 1.20593944099379 0.569313776237549 0.71325958897943 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/552 28/18639 0.0357142857142857 1.20593944099379 0.569313776237549 0.71325958897943 GO:0141052 histone H3 demethylase activity 1/552 28/18639 0.0357142857142857 1.20593944099379 0.569313776237549 0.71325958897943 GO:0004842 ubiquitin-protein transferase activity 13/552 449/18639 0.0289532293986637 0.977643555727704 0.572952972201725 0.716800739690669 GO:0003785 actin monomer binding 1/552 29/18639 0.0344827586206897 1.16435532233883 0.582087877334582 0.724120603397886 GO:0004629 phospholipase C activity 1/552 29/18639 0.0344827586206897 1.16435532233883 0.582087877334582 0.724120603397886 GO:0016417 S-acyltransferase activity 1/552 29/18639 0.0344827586206897 1.16435532233883 0.582087877334582 0.724120603397886 GO:0099604 ligand-gated calcium channel activity 1/552 29/18639 0.0344827586206897 1.16435532233883 0.582087877334582 0.724120603397886 GO:0008235 metalloexopeptidase activity 2/552 66/18639 0.0303030303030303 1.02322134387352 0.586002957561766 0.727964237421799 GO:0005253 monoatomic anion channel activity 3/552 103/18639 0.029126213592233 0.983484592655129 0.592114013056692 0.733335219279562 GO:0001965 G-protein alpha-subunit binding 1/552 30/18639 0.0333333333333333 1.12554347826087 0.594483766196017 0.733335219279562 GO:0031210 phosphatidylcholine binding 1/552 30/18639 0.0333333333333333 1.12554347826087 0.594483766196017 0.733335219279562 GO:0032452 histone demethylase activity 1/552 30/18639 0.0333333333333333 1.12554347826087 0.594483766196017 0.733335219279562 GO:0033612 receptor serine/threonine kinase binding 1/552 30/18639 0.0333333333333333 1.12554347826087 0.594483766196017 0.733335219279562 GO:0061630 ubiquitin protein ligase activity 10/552 353/18639 0.028328611898017 0.956552531099889 0.601695657554136 0.738861680698764 GO:0030145 manganese ion binding 2/552 68/18639 0.0294117647058824 0.993126598465473 0.602314680751033 0.738861680698764 GO:0140223 general transcription initiation factor activity 2/552 68/18639 0.0294117647058824 0.993126598465473 0.602314680751033 0.738861680698764 GO:1990841 promoter-specific chromatin binding 2/552 68/18639 0.0294117647058824 0.993126598465473 0.602314680751033 0.738861680698764 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/552 31/18639 0.032258064516129 1.08923562412342 0.606512621108145 0.738873110245006 GO:0016411 acylglycerol O-acyltransferase activity 1/552 31/18639 0.032258064516129 1.08923562412342 0.606512621108145 0.738873110245006 GO:0070273 phosphatidylinositol-4-phosphate binding 1/552 31/18639 0.032258064516129 1.08923562412342 0.606512621108145 0.738873110245006 GO:0072349 modified amino acid transmembrane transporter activity 1/552 31/18639 0.032258064516129 1.08923562412342 0.606512621108145 0.738873110245006 GO:0140457 protein demethylase activity 1/552 31/18639 0.032258064516129 1.08923562412342 0.606512621108145 0.738873110245006 GO:0140104 molecular carrier activity 7/552 249/18639 0.0281124497991968 0.949253535882661 0.60862064037504 0.740402947831573 GO:0002039 p53 binding 2/552 69/18639 0.0289855072463768 0.978733459357278 0.610286783530106 0.740402947831573 GO:0008080 N-acetyltransferase activity 2/552 69/18639 0.0289855072463768 0.978733459357278 0.610286783530106 0.740402947831573 GO:0019888 protein phosphatase regulator activity 3/552 107/18639 0.0280373831775701 0.946718813490451 0.617969238022375 0.746903323662138 GO:0042910 xenobiotic transmembrane transporter activity 1/552 32/18639 0.03125 1.05519701086957 0.618185290559366 0.746903323662138 GO:0043425 bHLH transcription factor binding 1/552 32/18639 0.03125 1.05519701086957 0.618185290559366 0.746903323662138 GO:0016853 isomerase activity 5/552 180/18639 0.0277777777777778 0.937952898550725 0.619816268889948 0.747849451656545 GO:0140299 molecular sensor activity 2/552 71/18639 0.028169014084507 0.951163502755664 0.625864179101796 0.754115035475115 GO:0042923 neuropeptide binding 1/552 33/18639 0.0303030303030303 1.02322134387352 0.629512302953154 0.755414763543785 GO:0071889 14-3-3 protein binding 1/552 33/18639 0.0303030303030303 1.02322134387352 0.629512302953154 0.755414763543785 GO:0140416 transcription regulator inhibitor activity 1/552 33/18639 0.0303030303030303 1.02322134387352 0.629512302953154 0.755414763543785 GO:0016831 carboxy-lyase activity 1/552 34/18639 0.0294117647058824 0.993126598465473 0.640503876035486 0.764444409557914 GO:0051427 hormone receptor binding 1/552 34/18639 0.0294117647058824 0.993126598465473 0.640503876035486 0.764444409557914 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/552 34/18639 0.0294117647058824 0.993126598465473 0.640503876035486 0.764444409557914 GO:0090482 vitamin transmembrane transporter activity 1/552 34/18639 0.0294117647058824 0.993126598465473 0.640503876035486 0.764444409557914 GO:0043015 gamma-tubulin binding 1/552 35/18639 0.0285714285714286 0.964751552795031 0.651169926045076 0.775076754077944 GO:0061631 ubiquitin conjugating enzyme activity 1/552 35/18639 0.0285714285714286 0.964751552795031 0.651169926045076 0.775076754077944 GO:0031406 carboxylic acid binding 5/552 187/18639 0.0267379679144385 0.902842362241339 0.653140001470334 0.776373964011906 GO:0004175 endopeptidase activity 11/552 405/18639 0.0271604938271605 0.917109500805153 0.657613662353965 0.780639636872406 GO:0000993 RNA polymerase II complex binding 1/552 36/18639 0.0277777777777778 0.937952898550725 0.661520076594587 0.782007183960537 GO:0016409 palmitoyltransferase activity 1/552 36/18639 0.0277777777777778 0.937952898550725 0.661520076594587 0.782007183960537 GO:0045505 dynein intermediate chain binding 1/552 36/18639 0.0277777777777778 0.937952898550725 0.661520076594587 0.782007183960537 GO:0043177 organic acid binding 5/552 189/18639 0.0264550264550265 0.893288474810214 0.66231220682372 0.782007183960537 GO:0019787 ubiquitin-like protein transferase activity 13/552 479/18639 0.0271398747390397 0.916413270400291 0.665455740191008 0.784668399530038 GO:0061659 ubiquitin-like protein ligase activity 10/552 372/18639 0.0268817204301075 0.907696353436185 0.666805281625423 0.7852099578019 GO:0019213 deacetylase activity 1/552 37/18639 0.027027027027027 0.912602820211516 0.6715636672907 0.788707263049797 GO:0030551 cyclic nucleotide binding 1/552 37/18639 0.027027027027027 0.912602820211516 0.6715636672907 0.788707263049797 GO:0016757 glycosyltransferase activity 7/552 267/18639 0.0262172284644195 0.885258915486077 0.680472929478732 0.795914185659355 GO:0005109 frizzled binding 1/552 38/18639 0.0263157894736842 0.888586956521739 0.681309762100695 0.795914185659355 GO:0042162 telomeric DNA binding 1/552 38/18639 0.0263157894736842 0.888586956521739 0.681309762100695 0.795914185659355 GO:0042887 amide transmembrane transporter activity 1/552 38/18639 0.0263157894736842 0.888586956521739 0.681309762100695 0.795914185659355 GO:0015370 solute:sodium symporter activity 2/552 79/18639 0.0253164556962025 0.85484314804623 0.683346524617562 0.797237612053822 GO:0008514 organic anion transmembrane transporter activity 7/552 269/18639 0.0260223048327138 0.878677064813318 0.687919900678436 0.801513015057306 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/552 39/18639 0.0256410256410256 0.865802675585284 0.69076715747301 0.802709661253221 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/552 39/18639 0.0256410256410256 0.865802675585284 0.69076715747301 0.802709661253221 GO:0030971 receptor tyrosine kinase binding 2/552 81/18639 0.0246913580246914 0.833735909822866 0.696537262654466 0.808050984519808 GO:0015144 carbohydrate transmembrane transporter activity 1/552 40/18639 0.025 0.844157608695652 0.699944390218972 0.808050984519808 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/552 40/18639 0.025 0.844157608695652 0.699944390218972 0.808050984519808 GO:0032451 demethylase activity 1/552 40/18639 0.025 0.844157608695652 0.699944390218972 0.808050984519808 GO:0050997 quaternary ammonium group binding 1/552 40/18639 0.025 0.844157608695652 0.699944390218972 0.808050984519808 GO:0015079 potassium ion transmembrane transporter activity 4/552 160/18639 0.025 0.844157608695652 0.701536929807799 0.808803978309879 GO:0001530 lipopolysaccharide binding 1/552 41/18639 0.024390243902439 0.823568398727466 0.708849745162739 0.808803978309879 GO:0004812 aminoacyl-tRNA ligase activity 1/552 41/18639 0.024390243902439 0.823568398727466 0.708849745162739 0.808803978309879 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/552 41/18639 0.024390243902439 0.823568398727466 0.708849745162739 0.808803978309879 GO:0016875 ligase activity, forming carbon-oxygen bonds 1/552 41/18639 0.024390243902439 0.823568398727466 0.708849745162739 0.808803978309879 GO:0042287 MHC protein binding 1/552 41/18639 0.024390243902439 0.823568398727466 0.708849745162739 0.808803978309879 GO:0061650 ubiquitin-like protein conjugating enzyme activity 1/552 41/18639 0.024390243902439 0.823568398727466 0.708849745162739 0.808803978309879 GO:0140318 protein transporter activity 1/552 41/18639 0.024390243902439 0.823568398727466 0.708849745162739 0.808803978309879 GO:0140828 metal cation:monoatomic cation antiporter activity 1/552 41/18639 0.024390243902439 0.823568398727466 0.708849745162739 0.808803978309879 GO:0016755 aminoacyltransferase activity 13/552 496/18639 0.0262096774193548 0.885003944600281 0.712596013418473 0.812028015290818 GO:0005267 potassium channel activity 3/552 124/18639 0.0241935483870968 0.816926718092567 0.715102392818649 0.812152444036975 GO:0004527 exonuclease activity 2/552 84/18639 0.0238095238095238 0.803959627329193 0.715467629270669 0.812152444036975 GO:0051117 ATPase binding 2/552 84/18639 0.0238095238095238 0.803959627329193 0.715467629270669 0.812152444036975 GO:0043175 RNA polymerase core enzyme binding 1/552 42/18639 0.0238095238095238 0.803959627329193 0.717491262566233 0.813402690981256 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/552 43/18639 0.0232558139534884 0.785262891809909 0.725876745335681 0.820799088956501 GO:0008375 acetylglucosaminyltransferase activity 1/552 43/18639 0.0232558139534884 0.785262891809909 0.725876745335681 0.820799088956501 GO:0016790 thiolester hydrolase activity 1/552 44/18639 0.0227272727272727 0.767416007905138 0.734013766016188 0.827877418959435 GO:0019205 nucleobase-containing compound kinase activity 1/552 44/18639 0.0227272727272727 0.767416007905138 0.734013766016188 0.827877418959435 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/552 46/18639 0.0217391304347826 0.734050094517958 0.749571600018288 0.844345020710255 GO:0061749 forked DNA-dependent helicase activity 1/552 47/18639 0.0212765957446809 0.718432007400555 0.757006466731024 0.848871174737084 GO:0140938 histone H3 methyltransferase activity 1/552 47/18639 0.0212765957446809 0.718432007400555 0.757006466731024 0.848871174737084 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/552 47/18639 0.0212765957446809 0.718432007400555 0.757006466731024 0.848871174737084 GO:0005244 voltage-gated monoatomic ion channel activity 4/552 173/18639 0.023121387283237 0.780723799949736 0.757444555047483 0.848871174737084 GO:0008188 neuropeptide receptor activity 1/552 48/18639 0.0208333333333333 0.703464673913043 0.76422099073944 0.848871174737084 GO:0009378 four-way junction helicase activity 1/552 48/18639 0.0208333333333333 0.703464673913043 0.76422099073944 0.848871174737084 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/552 48/18639 0.0208333333333333 0.703464673913043 0.76422099073944 0.848871174737084 GO:0032266 phosphatidylinositol-3-phosphate binding 1/552 48/18639 0.0208333333333333 0.703464673913043 0.76422099073944 0.848871174737084 GO:0036121 double-stranded DNA helicase activity 1/552 48/18639 0.0208333333333333 0.703464673913043 0.76422099073944 0.848871174737084 GO:0043138 3'-5' DNA helicase activity 1/552 48/18639 0.0208333333333333 0.703464673913043 0.76422099073944 0.848871174737084 GO:0140693 molecular condensate scaffold activity 1/552 48/18639 0.0208333333333333 0.703464673913043 0.76422099073944 0.848871174737084 GO:0022832 voltage-gated channel activity 4/552 175/18639 0.0228571428571429 0.771801242236025 0.765283829110403 0.848871174737084 GO:0051213 dioxygenase activity 2/552 93/18639 0.021505376344086 0.726157082748948 0.766380678152582 0.848871174737084 GO:0015297 antiporter activity 3/552 135/18639 0.0222222222222222 0.75036231884058 0.767063861978975 0.848871174737084 GO:0035254 glutamate receptor binding 1/552 49/18639 0.0204081632653061 0.689108251996451 0.771221690707803 0.852402921308624 GO:0008276 protein methyltransferase activity 2/552 95/18639 0.0210526315789474 0.710869565217391 0.776560497554493 0.857229485410592 GO:0032813 tumor necrosis factor receptor superfamily binding 1/552 50/18639 0.02 0.675326086956522 0.778014892791143 0.857761419302235 GO:0016407 acetyltransferase activity 2/552 96/18639 0.0208333333333333 0.703464673913043 0.781503543325161 0.860531991526581 GO:0016597 amino acid binding 1/552 51/18639 0.0196078431372549 0.662084398976982 0.78460673631039 0.860725300280801 GO:0016830 carbon-carbon lyase activity 1/552 51/18639 0.0196078431372549 0.662084398976982 0.78460673631039 0.860725300280801 GO:0030544 Hsp70 protein binding 1/552 51/18639 0.0196078431372549 0.662084398976982 0.78460673631039 0.860725300280801 GO:0008170 N-methyltransferase activity 2/552 98/18639 0.0204081632653061 0.689108251996451 0.791102603007677 0.866773286773629 GO:0008146 sulfotransferase activity 1/552 53/18639 0.0188679245283019 0.637100082034454 0.797210003656488 0.871300152695195 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/552 53/18639 0.0188679245283019 0.637100082034454 0.797210003656488 0.871300152695195 GO:0022843 voltage-gated monoatomic cation channel activity 3/552 143/18639 0.020979020979021 0.708384007297051 0.799800899529361 0.873049991812991 GO:0008374 O-acyltransferase activity 1/552 55/18639 0.0181818181818182 0.613932806324111 0.809077075925842 0.881118449507119 GO:0015171 amino acid transmembrane transporter activity 2/552 102/18639 0.0196078431372549 0.662084398976982 0.80919041281266 0.881118449507119 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 5/552 229/18639 0.0218340611353712 0.737255553445984 0.812039146367369 0.883130119723821 GO:0170055 lipid transmembrane transporter activity 1/552 56/18639 0.0178571428571429 0.602969720496894 0.814748053868639 0.884146857467086 GO:0000287 magnesium ion binding 5/552 230/18639 0.0217391304347826 0.734050094517958 0.814978906032586 0.884146857467086 GO:0017116 single-stranded DNA helicase activity 1/552 58/18639 0.0172413793103448 0.582177661169415 0.825590540361159 0.894558791890101 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 1/552 59/18639 0.0169491525423729 0.572310243183493 0.830771855775865 0.899068437784433 GO:0022836 gated channel activity 7/552 318/18639 0.0220125786163522 0.743283429040197 0.834988980708134 0.902295194029976 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/552 60/18639 0.0166666666666667 0.562771739130435 0.835799516465408 0.902295194029976 GO:0004620 phospholipase activity 2/552 109/18639 0.018348623853211 0.619565217391304 0.83750760414928 0.902867793030837 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/552 61/18639 0.0163934426229508 0.553545972915182 0.840678071119109 0.902867793030837 GO:0016836 hydro-lyase activity 1/552 61/18639 0.0163934426229508 0.553545972915182 0.840678071119109 0.902867793030837 GO:0019001 guanyl nucleotide binding 9/552 400/18639 0.0225 0.759741847826087 0.841448215273637 0.902867793030837 GO:0032561 guanyl ribonucleotide binding 9/552 400/18639 0.0225 0.759741847826087 0.841448215273637 0.902867793030837 GO:0043022 ribosome binding 2/552 112/18639 0.0178571428571429 0.602969720496894 0.848437483602326 0.909261069911606 GO:0015291 secondary active transmembrane transporter activity 6/552 287/18639 0.0209059233449477 0.705915770337828 0.856328867824682 0.916604443472536 GO:0120013 lipid transfer activity 1/552 65/18639 0.0153846153846154 0.519481605351171 0.858787580962872 0.917010467807812 GO:0160215 deacylase activity 1/552 65/18639 0.0153846153846154 0.519481605351171 0.858787580962872 0.917010467807812 GO:0046873 metal ion transmembrane transporter activity 10/552 450/18639 0.0222222222222222 0.75036231884058 0.861678833863117 0.918186117025542 GO:0015294 solute:monoatomic cation symporter activity 2/552 116/18639 0.0172413793103448 0.582177661169415 0.861970640472958 0.918186117025542 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/552 67/18639 0.0149253731343284 0.503974691758598 0.867056452064731 0.921077454804413 GO:0042054 histone methyltransferase activity 1/552 67/18639 0.0149253731343284 0.503974691758598 0.867056452064731 0.921077454804413 GO:0015081 sodium ion transmembrane transporter activity 3/552 164/18639 0.0182926829268293 0.617676299045599 0.86781787408443 0.921077454804413 GO:0016279 protein-lysine N-methyltransferase activity 1/552 69/18639 0.0144927536231884 0.489366729678639 0.874841954701356 0.926060322324793 GO:0005525 GTP binding 8/552 378/18639 0.0211640211640212 0.714630779848171 0.875247927226656 0.926060322324793 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 3/552 167/18639 0.0179640718562874 0.606580317625618 0.875662481654056 0.926060322324793 GO:0016278 lysine N-methyltransferase activity 1/552 70/18639 0.0142857142857143 0.482375776397515 0.878562323091493 0.92690426909892 GO:0016782 transferase activity, transferring sulphur-containing groups 1/552 70/18639 0.0142857142857143 0.482375776397515 0.878562323091493 0.92690426909892 GO:0008528 G protein-coupled peptide receptor activity 2/552 122/18639 0.0163934426229508 0.553545972915182 0.880205717055861 0.927528605069617 GO:0003678 DNA helicase activity 1/552 74/18639 0.0135135135135135 0.456301410105758 0.892372066927592 0.938107464875014 GO:0003684 damaged DNA binding 1/552 74/18639 0.0135135135135135 0.456301410105758 0.892372066927592 0.938107464875014 GO:0044183 protein folding chaperone 1/552 75/18639 0.0133333333333333 0.450217391304348 0.895572208002516 0.939884875411367 GO:0001653 peptide receptor activity 2/552 128/18639 0.015625 0.527598505434783 0.896194081883174 0.939884875411367 GO:0016298 lipase activity 2/552 130/18639 0.0153846153846154 0.519481605351171 0.901066872541061 0.942753240309864 GO:0016798 hydrolase activity, acting on glycosyl bonds 2/552 130/18639 0.0153846153846154 0.519481605351171 0.901066872541061 0.942753240309864 GO:0016835 carbon-oxygen lyase activity 1/552 79/18639 0.0126582278481013 0.427421574023115 0.90745066396997 0.948307447418855 GO:0000049 tRNA binding 1/552 80/18639 0.0125 0.422078804347826 0.91020320887776 0.950058260627437 GO:0005216 monoatomic ion channel activity 9/552 448/18639 0.0200892857142857 0.678340935559006 0.917671360682319 0.955658042748728 GO:0008234 cysteine-type peptidase activity 3/552 187/18639 0.0160427807486631 0.541705417344804 0.918172236155742 0.955658042748728 GO:0005125 cytokine activity 4/552 234/18639 0.0170940170940171 0.577201783723523 0.91899630124877 0.955658042748728 GO:0046943 carboxylic acid transmembrane transporter activity 3/552 188/18639 0.0159574468085106 0.538824005550416 0.919902129584659 0.955658042748728 GO:0005342 organic acid transmembrane transporter activity 3/552 189/18639 0.0158730158730159 0.535973084886128 0.921598598467053 0.956294075115225 GO:0016209 antioxidant activity 1/552 86/18639 0.0116279069767442 0.392631445904955 0.925084650148957 0.957658053323216 GO:0050660 flavin adenine dinucleotide binding 1/552 86/18639 0.0116279069767442 0.392631445904955 0.925084650148957 0.957658053323216 GO:0004197 cysteine-type endopeptidase activity 1/552 88/18639 0.0113636363636364 0.383708003952569 0.929476303333956 0.961076318335931 GO:0015293 symporter activity 2/552 146/18639 0.0136986301369863 0.462552114353782 0.93301739784679 0.963608132202422 GO:0015085 calcium ion transmembrane transporter activity 2/552 147/18639 0.0136054421768707 0.459405501330967 0.934649743264417 0.964003973577356 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 1/552 91/18639 0.010989010989011 0.37105828953655 0.935586622882331 0.964003973577356 GO:0052689 carboxylic ester hydrolase activity 1/552 92/18639 0.0108695652173913 0.367025047258979 0.937503604991936 0.964852018206404 GO:0005261 monoatomic cation channel activity 6/552 341/18639 0.0175953079178886 0.594128522249139 0.940926652215326 0.96724627885072 GO:0140098 catalytic activity, acting on RNA 7/552 387/18639 0.0180878552971576 0.610760026963262 0.942976147855656 0.967526777357355 GO:0008168 methyltransferase activity 3/552 204/18639 0.0147058823529412 0.496563299232737 0.943393456380187 0.967526777357355 GO:0004518 nuclease activity 3/552 209/18639 0.0143540669856459 0.484683794466403 0.949309684000625 0.972463578732348 GO:0016741 transferase activity, transferring one-carbon groups 3/552 215/18639 0.013953488372093 0.471157735085945 0.955648591297242 0.977821412441029 GO:0004843 cysteine-type deubiquitinase activity 1/552 108/18639 0.00925925925925926 0.312650966183575 0.961468174242009 0.982636071473293 GO:0101005 deubiquitinase activity 1/552 115/18639 0.00869565217391304 0.293620037807183 0.968820351984306 0.989004109317313 GO:0004540 RNA nuclease activity 1/552 121/18639 0.00826446280991736 0.279060366510959 0.973996594402068 0.991636288346792 GO:0051082 unfolded protein binding 1/552 121/18639 0.00826446280991736 0.279060366510959 0.973996594402068 0.991636288346792 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/552 122/18639 0.00819672131147541 0.276772986457591 0.974771725619805 0.991636288346792 GO:0019783 ubiquitin-like protein peptidase activity 1/552 127/18639 0.0078740157480315 0.265876412187607 0.978314805947248 0.994094077010913 GO:0005262 calcium channel activity 1/552 131/18639 0.00763358778625954 0.257758048456688 0.980788072065349 0.994765971268013 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/552 132/18639 0.00757575757575758 0.255805335968379 0.981361066674163 0.994765971268013 GO:0016829 lyase activity 2/552 200/18639 0.01 0.337663043478261 0.98301146483898 0.994765971268013 GO:0016779 nucleotidyltransferase activity 1/552 136/18639 0.00735294117647059 0.248281649616368 0.983487445516674 0.994765971268013 GO:0140101 catalytic activity, acting on a tRNA 1/552 139/18639 0.00719424460431655 0.242923052862058 0.98492172733985 0.995075559580467 GO:0020037 heme binding 1/552 142/18639 0.00704225352112676 0.237790875688916 0.986231633321913 0.9952589251601 GO:0019842 vitamin binding 1/552 150/18639 0.00666666666666667 0.225108695652174 0.989195628110544 0.99547443539568 GO:0003924 GTPase activity 4/552 331/18639 0.0120845921450151 0.408052016287929 0.989418725626623 0.99547443539568 GO:0046906 tetrapyrrole binding 1/552 152/18639 0.00657894736842105 0.222146739130435 0.989831156283459 0.99547443539568 GO:0001664 G protein-coupled receptor binding 3/552 297/18639 0.0101010101010101 0.341073781291173 0.993535964460556 0.996911465359195 GO:0045182 translation regulator activity 4/552 356/18639 0.0112359550561798 0.379396678065462 0.99398672805852 0.996911465359195 GO:0003735 structural constituent of ribosome 1/552 175/18639 0.00571428571428571 0.192950310559006 0.994938350007869 0.996911465359195 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1/552 181/18639 0.00552486187845304 0.186554167667547 0.995781180251078 0.996911465359195 GO:0030371 translation repressor activity 2/552 329/18639 0.0060790273556231 0.20526628782873 0.999480057318065 0.999480057318065