ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 13/99 175/18639 0.0742857142857143 13.985974025974 8.62840379432082e-12 2.528122311736e-09 GO:0045296 cadherin binding 13/99 334/18639 0.0389221556886228 7.3279804028307 2.41100847975284e-08 3.5321274228379e-06 GO:0044548 S100 protein binding 3/99 14/18639 0.214285714285714 40.3441558441558 5.07065383637655e-05 0.00490536454333879 GO:0048306 calcium-dependent protein binding 5/99 80/18639 0.0625 11.7670454545455 6.69674340387549e-05 0.00490536454333879 GO:0003746 translation elongation factor activity 3/99 18/18639 0.166666666666667 31.3787878787879 0.000111929991183563 0.00655909748335682 GO:0001221 transcription coregulator binding 5/99 115/18639 0.0434782608695652 8.18577075098814 0.000369328171298406 0.0165536989131783 GO:0019843 rRNA binding 4/99 65/18639 0.0615384615384615 11.586013986014 0.000395480861406989 0.0165536989131783 GO:0051015 actin filament binding 6/99 209/18639 0.0287081339712919 5.40495867768595 0.0008720910538397 0.031940334846879 GO:0061134 peptidase regulator activity 6/99 226/18639 0.0265486725663717 4.99839098954143 0.00130442426174816 0.0396563477652463 GO:0008307 structural constituent of muscle 3/99 42/18639 0.0714285714285714 13.4480519480519 0.00143577330887174 0.0396563477652463 GO:1990948 ubiquitin ligase inhibitor activity 2/99 11/18639 0.181818181818182 34.2314049586777 0.00148880486490686 0.0396563477652463 GO:0004857 enzyme inhibitor activity 8/99 416/18639 0.0192307692307692 3.62062937062937 0.00167975006705009 0.0401272275907067 GO:0004859 phospholipase inhibitor activity 2/99 12/18639 0.166666666666667 31.3787878787879 0.00178038893747163 0.0401272275907067 GO:0003779 actin binding 8/99 443/18639 0.018058690744921 3.39995895752103 0.0024825257774756 0.0513332890561776 GO:0005523 tropomyosin binding 2/99 15/18639 0.133333333333333 25.1030303030303 0.00280318302013256 0.0513332890561776 GO:0055105 ubiquitin-protein transferase inhibitor activity 2/99 15/18639 0.133333333333333 25.1030303030303 0.00280318302013256 0.0513332890561776 GO:0061135 endopeptidase regulator activity 5/99 184/18639 0.0271739130434783 5.11610671936759 0.00300455481774556 0.0517843859764381 GO:0055102 lipase inhibitor activity 2/99 16/18639 0.125 23.5340909090909 0.00319257917434579 0.051968094337962 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 8/99 484/18639 0.0165289256198347 3.11194590533434 0.00424591057782412 0.064530902232333 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 2/99 19/18639 0.105263157894737 19.8181818181818 0.00450251324275076 0.064530902232333 GO:0001216 DNA-binding transcription activator activity 8/99 491/18639 0.0162932790224033 3.06758007776338 0.00462508172996243 0.064530902232333 GO:0038024 cargo receptor activity 3/99 65/18639 0.0461538461538462 8.68951048951049 0.00500255035268866 0.0666248751517172 GO:1990841 promoter-specific chromatin binding 3/99 68/18639 0.0441176470588235 8.30614973262032 0.00567431187654527 0.0722857991229462 GO:0008135 translation factor activity, RNA binding 3/99 83/18639 0.036144578313253 6.80503833515882 0.00982552258516669 0.118967115265512 GO:0180051 translation factor activity 3/99 84/18639 0.0357142857142857 6.72402597402597 0.0101507777530301 0.118967115265512 GO:0004866 endopeptidase inhibitor activity 4/99 161/18639 0.0248447204968944 4.67758328627894 0.0107016792619408 0.120599693221102 GO:0072341 modified amino acid binding 3/99 91/18639 0.032967032967033 6.20679320679321 0.0126025665307963 0.13191859028649 GO:0030414 peptidase inhibitor activity 4/99 169/18639 0.0236686390532544 4.45615922538999 0.0126065547031458 0.13191859028649 GO:0055106 ubiquitin-protein transferase regulator activity 2/99 36/18639 0.0555555555555556 10.459595959596 0.0156456737235833 0.158075255207238 GO:0005200 structural constituent of cytoskeleton 3/99 112/18639 0.0267857142857143 5.04301948051948 0.0218378162816512 0.206402586145929 GO:0043022 ribosome binding 3/99 112/18639 0.0267857142857143 5.04301948051948 0.0218378162816512 0.206402586145929 GO:0001223 transcription coactivator binding 2/99 44/18639 0.0454545454545455 8.55785123966942 0.0228586686423628 0.209299684756634 GO:0001222 transcription corepressor binding 2/99 49/18639 0.0408163265306122 7.68460111317254 0.0279353146940053 0.248031733495259 GO:0005544 calcium-dependent phospholipid binding 2/99 53/18639 0.0377358490566038 7.10463121783877 0.0322905797632021 0.278268819724065 GO:0002020 protease binding 3/99 136/18639 0.0220588235294118 4.15307486631016 0.035895273815599 0.285018530589829 GO:0016504 peptidase activator activity 2/99 57/18639 0.0350877192982456 6.60606060606061 0.0368935036674602 0.285018530589829 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 2/99 58/18639 0.0344827586206897 6.49216300940439 0.0380814987918567 0.285018530589829 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 5/99 349/18639 0.0143266475644699 2.69731700963793 0.0384239215611871 0.285018530589829 GO:0001786 phosphatidylserine binding 2/99 59/18639 0.0338983050847458 6.38212634822804 0.0392840253389728 0.285018530589829 GO:0140297 DNA-binding transcription factor binding 6/99 488/18639 0.0122950819672131 2.31482861400894 0.0456657941511314 0.285018530589829 GO:0004090 carbonyl reductase (NADPH) activity 1/99 10/18639 0.1 18.8272727272727 0.0518749653819432 0.285018530589829 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/99 10/18639 0.1 18.8272727272727 0.0518749653819432 0.285018530589829 GO:0005131 growth hormone receptor binding 1/99 10/18639 0.1 18.8272727272727 0.0518749653819432 0.285018530589829 GO:0008239 dipeptidyl-peptidase activity 1/99 10/18639 0.1 18.8272727272727 0.0518749653819432 0.285018530589829 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/99 10/18639 0.1 18.8272727272727 0.0518749653819432 0.285018530589829 GO:0008028 monocarboxylic acid transmembrane transporter activity 2/99 70/18639 0.0285714285714286 5.37922077922078 0.0534192107747395 0.285018530589829 GO:0008199 ferric iron binding 1/99 11/18639 0.0909090909090909 17.1157024793388 0.0569135814336469 0.285018530589829 GO:0050786 RAGE receptor binding 1/99 11/18639 0.0909090909090909 17.1157024793388 0.0569135814336469 0.285018530589829 GO:0097493 structural molecule activity conferring elasticity 1/99 11/18639 0.0909090909090909 17.1157024793388 0.0569135814336469 0.285018530589829 GO:0005201 extracellular matrix structural constituent 3/99 168/18639 0.0178571428571429 3.36201298701299 0.0602959593016057 0.285018530589829 GO:0035259 nuclear glucocorticoid receptor binding 1/99 12/18639 0.0833333333333333 15.6893939393939 0.0619256898423901 0.285018530589829 GO:0035497 cAMP response element binding 1/99 12/18639 0.0833333333333333 15.6893939393939 0.0619256898423901 0.285018530589829 GO:0070008 serine-type exopeptidase activity 1/99 12/18639 0.0833333333333333 15.6893939393939 0.0619256898423901 0.285018530589829 GO:0097371 MDM2/MDM4 family protein binding 1/99 12/18639 0.0833333333333333 15.6893939393939 0.0619256898423901 0.285018530589829 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/99 12/18639 0.0833333333333333 15.6893939393939 0.0619256898423901 0.285018530589829 GO:0005542 folic acid binding 1/99 13/18639 0.0769230769230769 14.4825174825175 0.0669114286465776 0.285018530589829 GO:0071837 HMG box domain binding 1/99 13/18639 0.0769230769230769 14.4825174825175 0.0669114286465776 0.285018530589829 GO:0043021 ribonucleoprotein complex binding 3/99 177/18639 0.0169491525423729 3.19106317411402 0.0682590981108543 0.285018530589829 GO:0033192 calmodulin-dependent protein phosphatase activity 2/99 81/18639 0.0246913580246914 4.64870931537598 0.0690584015175523 0.285018530589829 GO:0140791 histone H2AXS140 phosphatase activity 2/99 81/18639 0.0246913580246914 4.64870931537598 0.0690584015175523 0.285018530589829 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 2/99 81/18639 0.0246913580246914 4.64870931537598 0.0690584015175523 0.285018530589829 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 2/99 81/18639 0.0246913580246914 4.64870931537598 0.0690584015175523 0.285018530589829 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 2/99 81/18639 0.0246913580246914 4.64870931537598 0.0690584015175523 0.285018530589829 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 2/99 81/18639 0.0246913580246914 4.64870931537598 0.0690584015175523 0.285018530589829 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 2/99 81/18639 0.0246913580246914 4.64870931537598 0.0690584015175523 0.285018530589829 GO:1990439 MAP kinase serine/threonine phosphatase activity 2/99 81/18639 0.0246913580246914 4.64870931537598 0.0690584015175523 0.285018530589829 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 2/99 82/18639 0.024390243902439 4.5920177383592 0.0705472002009496 0.285018530589829 GO:0033549 MAP kinase phosphatase activity 2/99 82/18639 0.024390243902439 4.5920177383592 0.0705472002009496 0.285018530589829 GO:0008191 metalloendopeptidase inhibitor activity 1/99 14/18639 0.0714285714285714 13.4480519480519 0.0718709351731533 0.285018530589829 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/99 14/18639 0.0714285714285714 13.4480519480519 0.0718709351731533 0.285018530589829 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 2/99 83/18639 0.0240963855421687 4.53669222343921 0.0720465008828207 0.285018530589829 GO:0017018 myosin phosphatase activity 2/99 84/18639 0.0238095238095238 4.48268398268398 0.0735561526664742 0.285018530589829 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/99 15/18639 0.0666666666666667 12.5515151515152 0.0768043460412259 0.285018530589829 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/99 15/18639 0.0666666666666667 12.5515151515152 0.0768043460412259 0.285018530589829 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/99 15/18639 0.0666666666666667 12.5515151515152 0.0768043460412259 0.285018530589829 GO:0140161 monocarboxylate:sodium symporter activity 1/99 15/18639 0.0666666666666667 12.5515151515152 0.0768043460412259 0.285018530589829 GO:0016651 oxidoreductase activity, acting on NAD(P)H 2/99 88/18639 0.0227272727272727 4.27892561983471 0.0796952974032937 0.285018530589829 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 2/99 89/18639 0.0224719101123595 4.23084780388151 0.0812544856373526 0.285018530589829 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 2/99 89/18639 0.0224719101123595 4.23084780388151 0.0812544856373526 0.285018530589829 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 1/99 16/18639 0.0625 11.7670454545455 0.0817117971656847 0.285018530589829 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/99 16/18639 0.0625 11.7670454545455 0.0817117971656847 0.285018530589829 GO:0015378 sodium:chloride symporter activity 1/99 16/18639 0.0625 11.7670454545455 0.0817117971656847 0.285018530589829 GO:0016722 oxidoreductase activity, acting on metal ions 1/99 16/18639 0.0625 11.7670454545455 0.0817117971656847 0.285018530589829 GO:0017070 U6 snRNA binding 1/99 16/18639 0.0625 11.7670454545455 0.0817117971656847 0.285018530589829 GO:0140793 histone H2AXY142 phosphatase activity 2/99 90/18639 0.0222222222222222 4.18383838383838 0.0828231461023092 0.28549625656443 GO:0005092 GDP-dissociation inhibitor activity 1/99 17/18639 0.0588235294117647 11.0748663101604 0.0865934237607875 0.289745599656426 GO:1990226 histone methyltransferase binding 1/99 17/18639 0.0588235294117647 11.0748663101604 0.0865934237607875 0.289745599656426 GO:0051020 GTPase binding 4/99 315/18639 0.0126984126984127 2.39076479076479 0.0870225691800871 0.289745599656426 GO:0004867 serine-type endopeptidase inhibitor activity 2/99 95/18639 0.0210526315789474 3.96363636363636 0.090803599205662 0.291246332399075 GO:0000400 four-way junction DNA binding 1/99 18/18639 0.0555555555555556 10.459595959596 0.0914493603437367 0.291246332399075 GO:0015373 monoatomic anion:sodium symporter activity 1/99 18/18639 0.0555555555555556 10.459595959596 0.0914493603437367 0.291246332399075 GO:0098641 cadherin binding involved in cell-cell adhesion 1/99 18/18639 0.0555555555555556 10.459595959596 0.0914493603437367 0.291246332399075 GO:0003714 transcription corepressor activity 3/99 204/18639 0.0147058823529412 2.76871657754011 0.0947934285413832 0.296946989855824 GO:0004725 protein tyrosine phosphatase activity 2/99 98/18639 0.0204081632653061 3.84230055658627 0.0956966258725142 0.296946989855824 GO:0008301 DNA binding, bending 1/99 19/18639 0.0526315789473684 9.90909090909091 0.0962797407382363 0.296946989855824 GO:0005516 calmodulin binding 3/99 207/18639 0.0144927536231884 2.72859025032938 0.097970967815324 0.299015558019687 GO:0004722 protein serine/threonine phosphatase activity 2/99 103/18639 0.0194174757281553 3.65578111209179 0.104014662511761 0.307111474152978 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/99 21/18639 0.0476190476190476 8.96536796536797 0.105864364810412 0.307111474152978 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/99 21/18639 0.0476190476190476 8.96536796536797 0.105864364810412 0.307111474152978 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/99 21/18639 0.0476190476190476 8.96536796536797 0.105864364810412 0.307111474152978 GO:0061891 calcium ion sensor activity 1/99 21/18639 0.0476190476190476 8.96536796536797 0.105864364810412 0.307111474152978 GO:0015377 chloride:monoatomic cation symporter activity 1/99 22/18639 0.0454545454545455 8.55785123966942 0.110618872699754 0.311647400971424 GO:0061133 endopeptidase activator activity 1/99 22/18639 0.0454545454545455 8.55785123966942 0.110618872699754 0.311647400971424 GO:0140784 metal ion sensor activity 1/99 22/18639 0.0454545454545455 8.55785123966942 0.110618872699754 0.311647400971424 GO:0004602 glutathione peroxidase activity 1/99 23/18639 0.0434782608695652 8.18577075098814 0.115348352830963 0.315860442798806 GO:0005283 amino acid:sodium symporter activity 1/99 23/18639 0.0434782608695652 8.18577075098814 0.115348352830963 0.315860442798806 GO:0017134 fibroblast growth factor binding 1/99 23/18639 0.0434782608695652 8.18577075098814 0.115348352830963 0.315860442798806 GO:0015295 solute:proton symporter activity 1/99 24/18639 0.0416666666666667 7.84469696969697 0.120052935612965 0.325699167912951 GO:0003707 nuclear steroid receptor activity 1/99 25/18639 0.04 7.53090909090909 0.124732750782146 0.332242690719716 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/99 25/18639 0.04 7.53090909090909 0.124732750782146 0.332242690719716 GO:0015294 solute:monoatomic cation symporter activity 2/99 116/18639 0.0172413793103448 3.24608150470219 0.126491454119505 0.332549673069276 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/99 26/18639 0.0384615384615385 7.24125874125874 0.129387927405793 0.332549673069276 GO:0008198 ferrous iron binding 1/99 26/18639 0.0384615384615385 7.24125874125874 0.129387927405793 0.332549673069276 GO:0070412 R-SMAD binding 1/99 26/18639 0.0384615384615385 7.24125874125874 0.129387927405793 0.332549673069276 GO:0046982 protein heterodimerization activity 4/99 369/18639 0.010840108401084 2.04089677260409 0.133365995308891 0.332774983122477 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/99 27/18639 0.037037037037037 6.97306397306397 0.134018593885503 0.332774983122477 GO:0005044 scavenger receptor activity 1/99 27/18639 0.037037037037037 6.97306397306397 0.134018593885503 0.332774983122477 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/99 27/18639 0.037037037037037 6.97306397306397 0.134018593885503 0.332774983122477 GO:0015108 chloride transmembrane transporter activity 2/99 121/18639 0.0165289256198347 3.11194590533434 0.135422031293415 0.333434077050172 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/99 122/18639 0.0163934426229508 3.08643815201192 0.137225038356642 0.335057801987468 GO:0051019 mitogen-activated protein kinase binding 1/99 28/18639 0.0357142857142857 6.72402597402597 0.13862487796058 0.335678423491321 GO:0003785 actin monomer binding 1/99 29/18639 0.0344827586206897 6.49216300940439 0.143206906711421 0.341135151759726 GO:0005416 amino acid:monoatomic cation symporter activity 1/99 29/18639 0.0344827586206897 6.49216300940439 0.143206906711421 0.341135151759726 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/99 30/18639 0.0333333333333333 6.27575757575758 0.147764806562875 0.344512953807898 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/99 30/18639 0.0333333333333333 6.27575757575758 0.147764806562875 0.344512953807898 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 2/99 128/18639 0.015625 2.94176136363636 0.148152328258686 0.344512953807898 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/99 31/18639 0.032258064516129 6.0733137829912 0.152298703287593 0.348621250494257 GO:0072349 modified amino acid transmembrane transporter activity 1/99 31/18639 0.032258064516129 6.0733137829912 0.152298703287593 0.348621250494257 GO:0005179 hormone activity 2/99 132/18639 0.0151515151515152 2.85261707988981 0.15553366065744 0.350548942866383 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/99 132/18639 0.0151515151515152 2.85261707988981 0.15553366065744 0.350548942866383 GO:0051059 NF-kappaB binding 1/99 32/18639 0.03125 5.88352272727273 0.156808722009354 0.350724851517105 GO:0071889 14-3-3 protein binding 1/99 33/18639 0.0303030303030303 5.70523415977962 0.16129498720638 0.354503528871444 GO:0019838 growth factor binding 2/99 136/18639 0.0147058823529412 2.76871657754011 0.162984719156015 0.354503528871444 GO:0140789 histone phosphatase activity 2/99 136/18639 0.0147058823529412 2.76871657754011 0.162984719156015 0.354503528871444 GO:0015035 protein-disulfide reductase activity 1/99 34/18639 0.0294117647058824 5.53743315508021 0.165757622714634 0.354503528871444 GO:0051427 hormone receptor binding 1/99 34/18639 0.0294117647058824 5.53743315508021 0.165757622714634 0.354503528871444 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/99 34/18639 0.0294117647058824 5.53743315508021 0.165757622714634 0.354503528871444 GO:0005343 organic acid:sodium symporter activity 1/99 35/18639 0.0285714285714286 5.37922077922078 0.170196751731095 0.360004440630538 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 3/99 268/18639 0.0111940298507463 2.10753052917232 0.170787089582405 0.360004440630538 GO:0004033 aldo-keto reductase (NADPH) activity 1/99 36/18639 0.0277777777777778 5.22979797979798 0.174612496817024 0.365439011195629 GO:0043394 proteoglycan binding 1/99 37/18639 0.027027027027027 5.08845208845209 0.17900497990121 0.371974887312444 GO:0015293 symporter activity 2/99 146/18639 0.0136986301369863 2.57907845579078 0.181877743918043 0.375126077563116 GO:0001217 DNA-binding transcription repressor activity 3/99 278/18639 0.0107913669064748 2.03172007848267 0.183949491775219 0.375126077563116 GO:0008509 monoatomic anion transmembrane transporter activity 2/99 149/18639 0.0134228187919463 2.52715070164735 0.187609636669261 0.375126077563116 GO:0000217 DNA secondary structure binding 1/99 39/18639 0.0256410256410256 4.82750582750583 0.187720644636513 0.375126077563116 GO:0004177 aminopeptidase activity 1/99 40/18639 0.025 4.70681818181818 0.192044067011834 0.375126077563116 GO:0015036 disulfide oxidoreductase activity 1/99 40/18639 0.025 4.70681818181818 0.192044067011834 0.375126077563116 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/99 40/18639 0.025 4.70681818181818 0.192044067011834 0.375126077563116 GO:0061791 GTPase motor activity 1/99 40/18639 0.025 4.70681818181818 0.192044067011834 0.375126077563116 GO:1990606 membrane scission GTPase motor activity 1/99 40/18639 0.025 4.70681818181818 0.192044067011834 0.375126077563116 GO:0008137 NADH dehydrogenase (ubiquinone) activity 1/99 41/18639 0.024390243902439 4.5920177383592 0.196344708840203 0.380986752915096 GO:0019894 kinesin binding 1/99 42/18639 0.0238095238095238 4.48268398268398 0.200622688936171 0.386726630646699 GO:0001046 core promoter sequence-specific DNA binding 1/99 44/18639 0.0227272727272727 4.27892561983471 0.209111136125576 0.39528750248254 GO:0003954 NADH dehydrogenase activity 1/99 44/18639 0.0227272727272727 4.27892561983471 0.209111136125576 0.39528750248254 GO:0030020 extracellular matrix structural constituent conferring tensile strength 1/99 44/18639 0.0227272727272727 4.27892561983471 0.209111136125576 0.39528750248254 GO:0015103 inorganic anion transmembrane transporter activity 2/99 165/18639 0.0121212121212121 2.28209366391185 0.218556112232721 0.410493210796072 GO:0016830 carbon-carbon lyase activity 1/99 51/18639 0.0196078431372549 3.69162210338681 0.238124035109115 0.438807502003591 GO:0030544 Hsp70 protein binding 1/99 51/18639 0.0196078431372549 3.69162210338681 0.238124035109115 0.438807502003591 GO:0004721 phosphoprotein phosphatase activity 2/99 175/18639 0.0114285714285714 2.15168831168831 0.238124207571915 0.438807502003591 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/99 52/18639 0.0192307692307692 3.62062937062937 0.242181799286229 0.443495419942906 GO:0034212 protein N-acetyltransferase activity 1/99 53/18639 0.0188679245283019 3.55231560891938 0.246218168892441 0.448086481276305 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 1/99 54/18639 0.0185185185185185 3.48653198653199 0.250233255585632 0.449805790715277 GO:0017069 snRNA binding 1/99 54/18639 0.0185185185185185 3.48653198653199 0.250233255585632 0.449805790715277 GO:0098632 cell-cell adhesion mediator activity 1/99 55/18639 0.0181818181818182 3.42314049586777 0.254227170446919 0.451445823884529 GO:0140313 molecular sequestering activity 1/99 55/18639 0.0181818181818182 3.42314049586777 0.254227170446919 0.451445823884529 GO:0003924 GTPase activity 3/99 331/18639 0.00906344410876133 1.70639934084043 0.257409045167369 0.452279309209226 GO:0015078 proton transmembrane transporter activity 2/99 185/18639 0.0108108108108108 2.03538083538084 0.257783770095361 0.452279309209226 GO:0004601 peroxidase activity 1/99 57/18639 0.0175438596491228 3.3030303030303 0.262151926132106 0.457166901927049 GO:0046943 carboxylic acid transmembrane transporter activity 2/99 188/18639 0.0106382978723404 2.00290135396518 0.263690124319697 0.457166901927049 GO:0005342 organic acid transmembrane transporter activity 2/99 189/18639 0.0105820105820106 1.99230399230399 0.265659230456199 0.457271911906275 GO:0004879 nuclear receptor activity 1/99 59/18639 0.0169491525423729 3.19106317411402 0.269993313173329 0.457271911906275 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 1/99 59/18639 0.0169491525423729 3.19106317411402 0.269993313173329 0.457271911906275 GO:0070888 E-box binding 1/99 59/18639 0.0169491525423729 3.19106317411402 0.269993313173329 0.457271911906275 GO:0098531 ligand-modulated transcription factor activity 1/99 60/18639 0.0166666666666667 3.13787878787879 0.273883015110673 0.461193812801306 GO:0008236 serine-type peptidase activity 2/99 194/18639 0.0103092783505155 1.94095595126523 0.27550465227882 0.461273503529681 GO:0016836 hydro-lyase activity 1/99 61/18639 0.0163934426229508 3.08643815201192 0.277752199754844 0.46239428709187 GO:0017171 serine hydrolase activity 2/99 198/18639 0.0101010101010101 1.90174471992654 0.28337761198974 0.469094013067762 GO:0005507 copper ion binding 1/99 63/18639 0.0158730158730159 2.98845598845599 0.285429445112053 0.469836109088942 GO:0016829 lyase activity 2/99 200/18639 0.01 1.88272727272727 0.287311812350137 0.470292519656929 GO:0106310 protein serine kinase activity 3/99 361/18639 0.00831024930747922 1.56459330143541 0.30068458892136 0.489447691966436 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 1/99 68/18639 0.0147058823529412 2.76871657754011 0.304270937199878 0.492549086185438 GO:0008080 N-acetyltransferase activity 1/99 69/18639 0.0144927536231884 2.72859025032938 0.307979793869805 0.495813624196993 GO:0097110 scaffold protein binding 1/99 70/18639 0.0142857142857143 2.68961038961039 0.311669077682777 0.499011146235266 GO:0140299 molecular sensor activity 1/99 71/18639 0.0140845070422535 2.651728553137 0.315338890882702 0.502142907764302 GO:0005518 collagen binding 1/99 72/18639 0.0138888888888889 2.61489898989899 0.318989335184867 0.505210136265763 GO:0048029 monosaccharide binding 1/99 74/18639 0.0135135135135135 2.54422604422604 0.326232521330188 0.513903918009382 GO:0003725 double-stranded RNA binding 1/99 75/18639 0.0133333333333333 2.51030303030303 0.329825463985093 0.514036494402299 GO:0019003 GDP binding 1/99 75/18639 0.0133333333333333 2.51030303030303 0.329825463985093 0.514036494402299 GO:0017022 myosin binding 1/99 76/18639 0.0131578947368421 2.47727272727273 0.333399439371081 0.514137030188035 GO:0098631 cell adhesion mediator activity 1/99 76/18639 0.0131578947368421 2.47727272727273 0.333399439371081 0.514137030188035 GO:0015370 solute:sodium symporter activity 1/99 79/18639 0.0126582278481013 2.38319907940161 0.34400855048005 0.522152509441526 GO:0016835 carbon-oxygen lyase activity 1/99 79/18639 0.0126582278481013 2.38319907940161 0.34400855048005 0.522152509441526 GO:0046332 SMAD binding 1/99 79/18639 0.0126582278481013 2.38319907940161 0.34400855048005 0.522152509441526 GO:0000287 magnesium ion binding 2/99 230/18639 0.00869565217391304 1.63715415019763 0.345871478850949 0.522152509441526 GO:0000049 tRNA binding 1/99 80/18639 0.0125 2.35340909090909 0.347507642802381 0.522152509441526 GO:0001618 virus receptor activity 1/99 81/18639 0.0123456790123457 2.32435465768799 0.350988258318442 0.524691631057671 GO:0140272 exogenous protein binding 1/99 82/18639 0.0121951219512195 2.2960088691796 0.354450493603843 0.527177637695055 GO:0005254 chloride channel activity 1/99 83/18639 0.0120481927710843 2.26834611171961 0.357894444734587 0.529611476299161 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 1/99 86/18639 0.0116279069767442 2.1892177589852 0.368117546518377 0.539292205649422 GO:0016209 antioxidant activity 1/99 86/18639 0.0116279069767442 2.1892177589852 0.368117546518377 0.539292205649422 GO:0004197 cysteine-type endopeptidase activity 1/99 88/18639 0.0113636363636364 2.13946280991736 0.374843266077047 0.546413318211814 GO:0016410 N-acyltransferase activity 1/99 94/18639 0.0106382978723404 2.00290135396518 0.394598138209364 0.572362646016553 GO:0016407 acetyltransferase activity 1/99 96/18639 0.0104166666666667 1.96117424242424 0.401044772320384 0.578847873349125 GO:0004674 protein serine/threonine kinase activity 3/99 433/18639 0.0069284064665127 1.30442998110435 0.405049324952854 0.58176202064307 GO:0008514 organic anion transmembrane transporter activity 2/99 269/18639 0.00743494423791822 1.39979722879351 0.419507680998635 0.59446407366096 GO:0008238 exopeptidase activity 1/99 102/18639 0.00980392156862745 1.8458110516934 0.419979738047163 0.59446407366096 GO:0015171 amino acid transmembrane transporter activity 1/99 102/18639 0.00980392156862745 1.8458110516934 0.419979738047163 0.59446407366096 GO:0005253 monoatomic anion channel activity 1/99 103/18639 0.00970873786407767 1.8278905560459 0.423077434866137 0.595969655845088 GO:0016791 phosphatase activity 2/99 273/18639 0.00732600732600733 1.37928737928738 0.426836739890572 0.598388348267645 GO:0005126 cytokine receptor binding 2/99 275/18639 0.00727272727272727 1.36925619834711 0.430483536582725 0.60026479860655 GO:0008013 beta-catenin binding 1/99 106/18639 0.00943396226415094 1.77615780445969 0.432272602409495 0.60026479860655 GO:0022804 active transmembrane transporter activity 3/99 457/18639 0.00656455142231947 1.23592599960215 0.439073458434759 0.604635802445814 GO:0030246 carbohydrate binding 2/99 280/18639 0.00714285714285714 1.34480519480519 0.439547528740472 0.604635802445814 GO:0031267 small GTPase binding 2/99 283/18639 0.00706713780918728 1.3305493093479 0.44494882442983 0.609205633448318 GO:1902936 phosphatidylinositol bisphosphate binding 1/99 111/18639 0.00900900900900901 1.6961506961507 0.447276561508681 0.60954433731183 GO:0015291 secondary active transmembrane transporter activity 2/99 287/18639 0.00696864111498258 1.31200506810263 0.452106263970112 0.613273774737236 GO:0009055 electron transfer activity 1/99 116/18639 0.00862068965517241 1.6230407523511 0.461887894685609 0.623655083607757 GO:0022853 active monoatomic ion transmembrane transporter activity 1/99 118/18639 0.00847457627118644 1.59553158705701 0.467624780104094 0.628504865002292 GO:0031625 ubiquitin protein ligase binding 2/99 302/18639 0.00662251655629139 1.24683925346177 0.478478988613883 0.640156820382958 GO:0003712 transcription coregulator activity 3/99 495/18639 0.00606060606060606 1.14104683195592 0.491383850015855 0.653856563640029 GO:0005543 phospholipid binding 3/99 497/18639 0.00603621730382294 1.13645509420157 0.494074203252265 0.653856563640029 GO:0031490 chromatin DNA binding 1/99 128/18639 0.0078125 1.47088068181818 0.495413505556609 0.653856563640029 GO:0031072 heat shock protein binding 1/99 131/18639 0.00763358778625954 1.43719639139486 0.503466562615493 0.661505393929774 GO:0051087 protein-folding chaperone binding 1/99 134/18639 0.00746268656716418 1.40502035278155 0.511392372861653 0.667300504847536 GO:0044389 ubiquitin-like protein ligase binding 2/99 322/18639 0.0062111801242236 1.16939582156973 0.512432128295889 0.667300504847536 GO:0044325 transmembrane transporter binding 1/99 136/18639 0.00735294117647059 1.38435828877005 0.51660653789157 0.669759803549691 GO:0016922 nuclear receptor binding 1/99 137/18639 0.0072992700729927 1.37425348374253 0.519192926733852 0.670147698383342 GO:0070851 growth factor receptor binding 1/99 139/18639 0.00719424460431655 1.35448005232178 0.524324678074938 0.673803204719108 GO:0020037 heme binding 1/99 142/18639 0.00704225352112676 1.3258642765685 0.531920811028862 0.680579902320771 GO:0019842 vitamin binding 1/99 150/18639 0.00666666666666667 1.25515151515152 0.551595112371178 0.7026842083685 GO:0046906 tetrapyrrole binding 1/99 152/18639 0.00657894736842105 1.23863636363636 0.556384384752085 0.705618212799696 GO:0003774 cytoskeletal motor activity 1/99 153/18639 0.0065359477124183 1.23054070112894 0.558759997123457 0.705618212799696 GO:0005506 iron ion binding 1/99 154/18639 0.00649350649350649 1.22255017709563 0.561123015639349 0.705618212799696 GO:0005178 integrin binding 1/99 161/18639 0.0062111801242236 1.16939582156973 0.577317025515027 0.719565345756708 GO:0042578 phosphoric ester hydrolase activity 2/99 363/18639 0.00550964187327824 1.03731530177811 0.577414981049949 0.719565345756708 GO:0008083 growth factor activity 1/99 162/18639 0.00617283950617284 1.162177328844 0.579581643681171 0.719565345756708 GO:0015081 sodium ion transmembrane transporter activity 1/99 164/18639 0.00609756097560976 1.1480044345898 0.584074909207442 0.72208417045477 GO:0015399 primary active transmembrane transporter activity 1/99 166/18639 0.00602409638554217 1.1341730558598 0.588520632421781 0.724523299578075 GO:0005525 GTP binding 2/99 378/18639 0.00529100529100529 0.996151996151996 0.599580857825596 0.734425867019856 GO:0008201 heparin binding 1/99 172/18639 0.00581395348837209 1.0946088794926 0.601577501995787 0.734425867019856 GO:0015631 tubulin binding 2/99 385/18639 0.00519480519480519 0.978040141676505 0.609626486099558 0.738618327573048 GO:0004252 serine-type endopeptidase activity 1/99 176/18639 0.00568181818181818 1.06973140495868 0.610053362705384 0.738618327573048 GO:1901981 phosphatidylinositol phosphate binding 1/99 185/18639 0.00540540540540541 1.01769041769042 0.628476967736643 0.749895071628193 GO:0019001 guanyl nucleotide binding 2/99 400/18639 0.005 0.941363636363636 0.630513616025119 0.749895071628193 GO:0032561 guanyl ribonucleotide binding 2/99 400/18639 0.005 0.941363636363636 0.630513616025119 0.749895071628193 GO:0008234 cysteine-type peptidase activity 1/99 187/18639 0.0053475935828877 1.0068060281964 0.632452594993833 0.749895071628193 GO:0031406 carboxylic acid binding 1/99 187/18639 0.0053475935828877 1.0068060281964 0.632452594993833 0.749895071628193 GO:0043177 organic acid binding 1/99 189/18639 0.00529100529100529 0.996151996151996 0.636386104668596 0.749895071628193 GO:0004175 endopeptidase activity 2/99 405/18639 0.00493827160493827 0.929741863075196 0.637282842441707 0.749895071628193 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 1/99 229/18639 0.00436681222707424 0.822151647479158 0.706859470939022 0.777862221459873 GO:0005085 guanyl-nucleotide exchange factor activity 1/99 230/18639 0.00434782608695652 0.818577075098814 0.708435837716699 0.777862221459873 GO:0005539 glycosaminoglycan binding 1/99 242/18639 0.00413223140495868 0.777986476333584 0.72671016515451 0.777862221459873 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 1/99 243/18639 0.00411522633744856 0.774784885895997 0.728180823068828 0.777862221459873 GO:0004676 3-phosphoinositide-dependent protein kinase activity 1/99 245/18639 0.00408163265306122 0.768460111317254 0.731098676545123 0.777862221459873 GO:0004711 ribosomal protein S6 kinase activity 1/99 245/18639 0.00408163265306122 0.768460111317254 0.731098676545123 0.777862221459873 GO:0035175 histone H3S10 kinase activity 1/99 245/18639 0.00408163265306122 0.768460111317254 0.731098676545123 0.777862221459873 GO:0035979 histone H2AXS139 kinase activity 1/99 245/18639 0.00408163265306122 0.768460111317254 0.731098676545123 0.777862221459873 GO:0044022 histone H3S28 kinase activity 1/99 245/18639 0.00408163265306122 0.768460111317254 0.731098676545123 0.777862221459873 GO:0044023 histone H4S1 kinase activity 1/99 245/18639 0.00408163265306122 0.768460111317254 0.731098676545123 0.777862221459873 GO:0044024 histone H2AS1 kinase activity 1/99 245/18639 0.00408163265306122 0.768460111317254 0.731098676545123 0.777862221459873 GO:0044025 histone H2BS14 kinase activity 1/99 245/18639 0.00408163265306122 0.768460111317254 0.731098676545123 0.777862221459873 GO:0072354 histone H3T3 kinase activity 1/99 245/18639 0.00408163265306122 0.768460111317254 0.731098676545123 0.777862221459873 GO:0072371 histone H2AS121 kinase activity 1/99 245/18639 0.00408163265306122 0.768460111317254 0.731098676545123 0.777862221459873 GO:0072518 Rho-dependent protein serine/threonine kinase activity 1/99 245/18639 0.00408163265306122 0.768460111317254 0.731098676545123 0.777862221459873 GO:0140823 histone H2BS36 kinase activity 1/99 245/18639 0.00408163265306122 0.768460111317254 0.731098676545123 0.777862221459873 GO:0140855 histone H3S57 kinase activity 1/99 245/18639 0.00408163265306122 0.768460111317254 0.731098676545123 0.777862221459873 GO:0140995 histone H2A kinase activity 1/99 245/18639 0.00408163265306122 0.768460111317254 0.731098676545123 0.777862221459873 GO:0140997 histone H4 kinase activity 1/99 245/18639 0.00408163265306122 0.768460111317254 0.731098676545123 0.777862221459873 GO:0140998 histone H2B kinase activity 1/99 245/18639 0.00408163265306122 0.768460111317254 0.731098676545123 0.777862221459873 GO:1990244 histone H2AT120 kinase activity 1/99 245/18639 0.00408163265306122 0.768460111317254 0.731098676545123 0.777862221459873 GO:0004677 DNA-dependent protein kinase activity 1/99 246/18639 0.0040650406504065 0.765336289726534 0.732545954517399 0.777862221459873 GO:0140857 histone H3T45 kinase activity 1/99 246/18639 0.0040650406504065 0.765336289726534 0.732545954517399 0.777862221459873 GO:0033218 amide binding 1/99 247/18639 0.00404858299595142 0.762237762237762 0.733985521227711 0.777862221459873 GO:0035402 histone H3T11 kinase activity 1/99 247/18639 0.00404858299595142 0.762237762237762 0.733985521227711 0.777862221459873 GO:0035403 histone H3T6 kinase activity 1/99 247/18639 0.00404858299595142 0.762237762237762 0.733985521227711 0.777862221459873 GO:0004679 AMP-activated protein kinase activity 1/99 248/18639 0.00403225806451613 0.7591642228739 0.735417417345505 0.777862221459873 GO:0030695 GTPase regulator activity 2/99 489/18639 0.00408997955010225 0.770031604387433 0.737005591161068 0.777862221459873 GO:0060589 nucleoside-triphosphatase regulator activity 2/99 490/18639 0.00408163265306122 0.768460111317254 0.738039923432917 0.777862221459873 GO:0003730 mRNA 3'-UTR binding 1/99 262/18639 0.00381679389312977 0.718598195697432 0.75468082713047 0.792550115947052 GO:0005096 GTPase activator activity 1/99 271/18639 0.003690036900369 0.694733310969473 0.766324381337973 0.801903727614379 GO:1901681 sulfur compound binding 1/99 275/18639 0.00363636363636364 0.684628099173554 0.771322069842827 0.802689987514891 GO:0008017 microtubule binding 1/99 276/18639 0.0036231884057971 0.682147562582345 0.772554868529691 0.802689987514891 GO:0035091 phosphatidylinositol binding 1/99 284/18639 0.00352112676056338 0.662932138284251 0.782183302700197 0.809822288661335 GO:0061630 ubiquitin protein ligase activity 1/99 353/18639 0.0028328611898017 0.533350502189029 0.850126503561751 0.873605394249622 GO:0141003 histone H2AX kinase activity 1/99 354/18639 0.00282485875706215 0.531843862352337 0.850937915360252 0.873605394249622 GO:0140996 histone H3 kinase activity 1/99 357/18639 0.00280112044817927 0.527374586198116 0.853346149940097 0.873605394249622 GO:0035173 histone kinase activity 1/99 360/18639 0.00277777777777778 0.522979797979798 0.85571586399195 0.873605394249622 GO:0061659 ubiquitin-like protein ligase activity 1/99 372/18639 0.00268817204301075 0.506109481915934 0.864821571625584 0.879835835021861 GO:0005216 monoatomic ion channel activity 1/99 448/18639 0.00223214285714286 0.420251623376623 0.910634689071092 0.917870090706981 GO:0004842 ubiquitin-protein transferase activity 1/99 449/18639 0.0022271714922049 0.419315650941486 0.911121037583102 0.917870090706981 GO:0046873 metal ion transmembrane transporter activity 1/99 450/18639 0.00222222222222222 0.418383838383838 0.911604765855739 0.917870090706981 GO:0019787 ubiquitin-like protein transferase activity 1/99 479/18639 0.00208768267223382 0.393053710381477 0.924553635652813 0.927719915226966 GO:0016755 aminoacyltransferase activity 1/99 496/18639 0.00201612903225806 0.37958211143695 0.931251757327056 0.931251757327056