category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	23/152	238/9376	5.96107916850951	RPS26/RPS10/RPL17/RPL23A/RPL36A/RPS11/RPS16/RPS4Y1/RPS20/FOS/RPL41/RPL26/RPLP0/RPL23/RPL21/RPL4/RPL13A/RPL9/RPS8/RPS25/RPS27L/RPS2/JUN	9.95146097459497
Genetic Information Processing	Translation	hsa03010	Ribosome	21/152	222/9376	5.83499288762447	RPS26/RPS10/RPL17/RPL23A/RPL36A/RPS11/RPS16/RPS4Y1/RPS20/RPL41/RPL26/RPLP0/RPL23/RPL21/RPL4/RPL13A/RPL9/RPS8/RPS25/RPS27L/RPS2	9.35868129317659
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	10/152	142/9376	4.34395848776872	DUSP1/FOS/ACTG1/PDGFA/KLF2/CAV2/HMOX1/SDC1/JUN/CALM2	5.15416003988309
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	9/152	116/9376	4.78584392014519	CD99/CLDN4/ACTG1/RAP1B/CLDN3/ACTN4/CLDN23/ACTN1/VCL	5.26664434470601
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	12/152	203/9376	3.64635727249157	FN1/FLNB/ACTG1/RAP1B/PDGFA/ACTN4/CAV2/ACTN1/ITGB6/VCL/CAPN2/JUN	4.89315060652063
NA	NA	hsa04382	Cornified envelope formation	12/152	217/9376	3.4111084162018	KRT19/S100A6/COL17A1/S100A10/CLDN4/KRT8/PPP2R2B/PRSS8/CLDN3/KRT18/CLDN23/DSP	4.6128609287556
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	10/152	170/9376	3.62848297213622	CLDN4/MYL6/ACTG1/MYH9/PPP2R2B/CLDN3/ACTN4/CLDN23/ACTN1/JUN	4.4395804302754
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	11/152	233/9376	2.91213011068444	FN1/TPM1/ACTG1/MYH9/FHL2/TPM4/ITGB6/SDC1/VCL/DSP/PDLIM3	3.79401310029071
NA	NA	hsa04518	Integrin signaling	8/152	154/9376	3.20437457279563	FN1/FLNB/ACTG1/PDGFA/ACTN4/ACTN1/ITGB6/VCL	3.5406335423594
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	4/152	42/9376	5.87468671679198	FTH1/TFRC/PRNP/HMOX1	4.06429517758145
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	7/152	137/9376	3.15174798309643	GADD45A/FOS/ACTG1/CTSV/CTSH/CAPN2/JUN	3.2567692558076
NA	NA	hsa03272	Virion - Hepatitis viruses	4/152	48/9376	5.14035087719298	CLDN4/CLDN3/CLDN23/DPP4	3.69157148179351
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	4/152	50/9376	4.93473684210526	AOC1/OAT/CNDP2/P4HA1	3.58097074801395
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	8/152	200/9376	2.46736842105263	CLDN4/FOS/ACTG1/MYH9/CLDN3/TUBB6/CLDN23/JUN	2.69262112595402
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	5/152	93/9376	3.31635540464063	ACTG1/RAP1B/ACTN4/ACTN1/VCL	2.88171003737376
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	4/152	67/9376	3.68263943440691	LDHA/PKM/TPI1/ALDOA	2.82875917502904
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	4/152	69/9376	3.57589626239512	FOSB/FOS/JUN/CALM2	2.75674021917583
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	5/152	103/9376	2.9943791517629	FN1/SERPINB9/ACTN4/ACTN1/VCL	2.61254628365934
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	9/152	268/9376	2.07148468185389	NDUFA13/NDUFA7/DUSP1/PSMA2/TUBB6/UBE2L6/PSMD9/UBC/CALM2	2.28449197994882
NA	NA	hsa03273	Virion - Lassa virus and SFTS virus	2/152	17/9376	7.25696594427245	TFRC/MYH9	3.31452510842407
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	5/152	110/9376	2.80382775119617	LDHA/TFRC/ALDOA/SERPINE1/HMOX1	2.44282886891781
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	4/152	75/9376	3.28982456140351	PKM/TPI1/ALDOA/TALDO1	2.55573490259169
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	4/152	76/9376	3.24653739612188	PLIN2/SLC27A6/SCD/UBC	2.52421741800087
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	8/152	232/9376	2.12704174228675	FN1/ACTG1/MYH9/PDGFA/ACTN4/ACTN1/ITGB6/VCL	2.23132930940257
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	4/152	78/9376	3.16329284750337	FN1/ACTG1/CAV2/VCL	2.46272335970883
Genetic Information Processing	Folding, sorting and degradation	hsa03050	Proteasome	3/152	46/9376	4.02288329519451	PSMA2/PSMB8/PSMD9	2.6381972277437
Cellular Processes	Cell motility	hsa04814	Motor proteins	7/152	194/9376	2.22571893651655	TPM1/MYL6/ACTG1/MYH9/TUBB6/TPM4/DYNLL1	2.21447561054399
Metabolism	Glycan biosynthesis and metabolism	hsa00541	Biosynthesis of various nucleotide sugars	2/152	20/9376	6.16842105263158	CYB5R1/UGP2	2.97013071605828
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	6/152	156/9376	2.37246963562753	CLDN4/PPP2R2B/CLDN3/YWHAZ/CLDN23/EIF3E	2.21894924543664
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	8/152	248/9376	1.98981324278438	S100A10/FOS/ACTG1/TUBB6/AHNAK/ANXA2/JUN/DYNLL1	2.02786514075936
Metabolism	Amino acid metabolism	hsa00340	Histidine metabolism	2/152	22/9376	5.60765550239234	AOC1/CNDP2	2.7774128703748
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	3/152	51/9376	3.62848297213622	ATP6V1B1/ACTG1/KDELR2	2.41609285347276
NA	NA	hsa04517	IgSF CAM signaling	9/152	299/9376	1.85671536701285	MYL6/ACTG1/MYH9/RAP1B/TUBB6/ACTN4/ACTN1/VCL/DYNLL1	1.93263022995265
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	9/152	300/9376	1.85052631578947	GADD45A/DUSP1/FOS/EFNA1/NR4A1/RAP1B/PDGFA/DUSP5/JUN	1.92198026620586
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	4/152	89/9376	2.77232406859846	FN1/ITGB6/SDC1/SV2A	2.15649373571815
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	5/152	139/9376	2.21885649375237	KRT19/FOS/KRT18/JUN/CALM2	1.85841323123189
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	4/152	99/9376	2.4922913343966	SLC44A2/FOS/PDGFA/JUN	1.91608698573203
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	4/152	99/9376	2.4922913343966	TPM1/ACTG1/TPM4/ITGB6	1.91608698573203
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	5/152	142/9376	2.17197924388436	FOSB/FOS/FHL2/JUNB/JUN	1.80641255221795
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	4/152	103/9376	2.39550332141032	FOS/SERPINE1/PPP2R2B/JUN	1.82804609292177
Metabolism	Carbohydrate metabolism	hsa00030	Pentose phosphate pathway	2/152	31/9376	3.97962648556876	ALDOA/TALDO1	2.13304886742959
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	4/152	105/9376	2.34987468671679	PLK3/JUN/EGR2/CALM2	1.78555239015708
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	4/152	105/9376	2.34987468671679	TPM1/ACTG1/TPM4/ITGB6	1.78555239015708
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	4/152	109/9376	2.2636407532593	GATA3/FOS/EBI3/JUN	1.70339385516412
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	5/152	154/9376	2.00273410799727	MYL6/FOS/ACTG1/JUN/CALM2	1.61057656019884
Metabolism	Carbohydrate metabolism	hsa00051	Fructose and mannose metabolism	2/152	35/9376	3.52481203007519	TPI1/ALDOA	1.92094164534682
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	5/152	157/9376	1.96446530338585	ZFP36L1/GADD45A/SERPINE1/CAPN2/CALM2	1.56438020621073
Metabolism	Glycan biosynthesis and metabolism	hsa00512	Mucin type O-glycan biosynthesis	2/152	36/9376	3.42690058479532	GALNT6/GALNT7	1.87274041784967
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	6/152	205/9376	1.80539152759949	PKM/ACTN4/YWHAZ/ACTN1/JUN/EGR2	1.49666094336068
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	7/152	253/9376	1.70667776159767	ACTG1/ACTN4/ACTN1/VCL/CAPN2/JUN/UBC	1.46271809139212
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	5/152	160/9376	1.92763157894737	CD99/CLDN4/CLDN3/CLDN23/SDC1	1.51918991259566
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	4/152	116/9376	2.12704174228675	PKM/TPI1/ALDOA/TALDO1	1.56787446695227
Human Diseases	Cancer: specific types	hsa05214	Glioma	3/152	76/9376	2.43490304709141	GADD45A/PDGFA/CALM2	1.61226217327306
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	4/152	120/9376	2.05614035087719	ARHGDIB/RAP1B/JUN/CALM2	1.49468050698638
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	3/152	78/9376	2.37246963562753	BTG2/TOB1/BTG1	1.56243896246031
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	3/152	78/9376	2.37246963562753	FOS/JUN/CALM2	1.56243896246031
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	11/152	480/9376	1.41359649122807	GPX3/NDUFA13/NDUFA7/PRNP/PSMA2/TUBB6/UBE2L6/PSMD9/CAPN2/UBC/CALM2	1.19411969767969
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	7/152	275/9376	1.57014354066986	NDUFA13/NDUFA7/PRNP/PSMA2/TUBB6/CAV2/PSMD9	1.2318385276383
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	2/152	44/9376	2.80382775119617	ARHGDIB/DYNLL1	1.53950754719748
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	6/152	227/9376	1.63041966148852	CBR1/NDUFA13/NDUFA7/FOS/HMOX1/JUN	1.23425145900374
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	3/152	86/9376	2.15177478580171	ACTG1/ITGB6/DSP	1.37738934955425
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	3/152	87/9376	2.12704174228675	GADD45A/FOS/JUN	1.3556979246674
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	2/152	46/9376	2.68192219679634	FTH1/HMOX1	1.46788415018291
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	4/152	134/9376	1.84131971720346	MYL6/MYH9/CALD1/CALM2	1.25915231794242
Metabolism	Carbohydrate metabolism	hsa00620	Pyruvate metabolism	2/152	47/9376	2.62486002239642	LDHA/PKM	1.4334914963727
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	4/152	138/9376	1.78794813119756	FN1/FOS/ACTG1/JUN	1.19700504025613
Metabolism	Glycan biosynthesis and metabolism	hsa00514	Other types of O-glycan biosynthesis	2/152	49/9376	2.51772287862513	GALNT6/GALNT7	1.36731103092107
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	2/152	49/9376	2.51772287862513	FOSB/JUN	1.36731103092107
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	3/152	93/9376	1.98981324278438	GATA3/FOS/JUN	1.23139771692321
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	3/152	94/9376	1.96864501679731	FOSB/FOS/JUN	1.21158971596694
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	3/152	95/9376	1.94792243767313	FOS/ATP6V1B1/JUN	1.19202401409822
NA	NA	hsa04519	Cadherin signaling	9/152	404/9376	1.37415320479416	KRT19/KRT8/ACTG1/ACTN4/KRT18/YWHAZ/ACTN1/VCL/DSP	0.986832183423957
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	5/152	196/9376	1.57357679914071	FOS/ZFP36/JUN/UBC/CALM2	1.04170813607425
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	2/152	54/9376	2.28460038986355	LDHA/CDO1	1.21522911255013
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	3/152	101/9376	1.83220427305888	FN1/SERPINE1/JUN	1.07939761512847
Metabolism	Amino acid metabolism	hsa00360	Phenylalanine metabolism	1/152	16/9376	3.85526315789474	MIF	1.46729012110574
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	3/152	103/9376	1.79662749105774	COL17A1/PRCP/DPP4	1.0435459021842
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	8/152	362/9376	1.36318697295725	FN1/CSH1/EFNA1/NR4A1/PPP2R2B/PDGFA/YWHAZ/ITGB6	0.904635353170994
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	5/152	204/9376	1.51186790505676	FN1/TIMP3/ACTG1/CAV2/SDC1	0.948830737228763
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	4/152	154/9376	1.60218728639781	TPM1/PPP2R2B/TPM4/CALM2	0.967224232811979
Metabolism	Metabolism of other amino acids	hsa00430	Taurine and hypotaurine metabolism	1/152	17/9376	3.62848297213622	CDO1	1.39239575311828
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	4/152	155/9376	1.5918505942275	TFRC/ATP6V1B1/ACTG1/TUBB6	0.953754743845893
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	8/152	368/9376	1.34096109839817	GPX3/NDUFA13/NDUFA7/ACTG1/HNRNPA1/PSMA2/TUBB6/PSMD9	0.856568968868051
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	4/152	157/9376	1.57157224270868	ACTG1/SERPINE1/PPP2R2B/YWHAZ	0.927100539308061
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	4/152	157/9376	1.57157224270868	NDUFA13/NDUFA7/FOS/JUN	0.927100539308061
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	3/152	107/9376	1.72946384653222	LDHA/PKM/CALM2	0.974152625104828
Organismal Systems	Digestive system	hsa04978	Mineral absorption	2/152	61/9376	2.02243313201035	FTH1/HMOX1	1.02838607479386
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	5/152	212/9376	1.45481628599801	ACTG1/EFNA1/RAP1B/PDGFA/CALM2	0.859823246497191
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	3/152	110/9376	1.6822966507177	TFRC/ID3/SKIL	0.923998399755118
Metabolism	Glycan biosynthesis and metabolism	hsa00531	Glycosaminoglycan degradation	1/152	19/9376	3.24653739612188	IDS	1.25825864536663
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	4/152	163/9376	1.513722957701	FOS/YWHAZ/JUN/EGR2	0.849317408516338
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	2/152	63/9376	1.95822890559733	CBR1/CYP2J2	0.979585900991437
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	5/152	216/9376	1.42787524366472	FOS/RAP1B/JUN/CYP2J2/CALM2	0.816665263088942
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	3/152	115/9376	1.6091533180778	GATA3/FOS/PDE4C	0.843712293760776
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	2/152	66/9376	1.86921850079745	GATA3/JUN	0.909649057253147
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	8/152	388/9376	1.27183939229517	NDUFA13/RTN4/NDUFA7/PSMA2/TUBB6/PSMD9/CAPN2/CALM2	0.702011952633425
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	3/152	117/9376	1.58164642375169	ACTG1/SMARCA1/MORF4L2	0.81267656456773
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	2/152	67/9376	1.84131971720346	RAP1B/CALM2	0.887145263969575
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	5/152	224/9376	1.37687969924812	FOS/B2M/ZFP36/JUN/EGR2	0.732852431526707
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	3/152	119/9376	1.55506413091552	FOS/JUNB/JUN	0.782220686990856
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	5/152	226/9376	1.36469492314858	FOS/RAP1B/PDE4C/JUN/CALM2	0.712395512640734
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	4/152	174/9376	1.41802782819117	KRTCAP2/PPP1R15A/CAPN2/NSFL1C	0.714474097469828
Organismal Systems	Endocrine system	hsa04614	Renin-angiotensin system	1/152	23/9376	2.68192219679634	PRCP	1.03667383649532
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	2/152	70/9376	1.76240601503759	RAP1B/JUN	0.821867098730391
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	3/152	122/9376	1.51682484900777	PPP2R2B/STRADB/SCD	0.737575256897664
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	3/152	122/9376	1.51682484900777	FOS/PPP2R2B/JUN	0.737575256897664
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	3/152	122/9376	1.51682484900777	CSH1/FOS/JUNB	0.737575256897664
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	2/152	71/9376	1.73758339510749	ATP6V1B1/JUN	0.800810763450914
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	2/152	71/9376	1.73758339510749	LDHA/PKM	0.800810763450914
Human Diseases	Cancer: specific types	hsa05218	Melanoma	2/152	73/9376	1.68997837058399	GADD45A/PDGFA	0.759684352748629
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	2/152	75/9376	1.64491228070175	GADD45A/SERPINE1	0.719803976549727
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	2/152	76/9376	1.62326869806094	ACTG1/CALM2	0.700306928545249
Metabolism	Lipid metabolism	hsa01040	Biosynthesis of unsaturated fatty acids	1/152	27/9376	2.28460038986355	SCD	0.858055020456713
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	2/152	78/9376	1.58164642375169	FOS/JUN	0.662154565211794
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	3/152	133/9376	1.39137316976652	GADD45A/PLK3/KLF2	0.583523268598051
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	3/152	133/9376	1.39137316976652	FOS/PPP2R2B/CALM2	0.583523268598051
Metabolism	Metabolism of cofactors and vitamins	hsa00790	Folate biosynthesis	1/152	28/9376	2.20300751879699	CBR1	0.818343788884997
Organismal Systems	Excretory system	hsa04966	Collecting duct acid secretion	1/152	28/9376	2.20300751879699	ATP6V1B1	0.818343788884997
Organismal Systems	Sensory system	hsa04744	Phototransduction	1/152	29/9376	2.12704174228675	CALM2	0.780280338958318
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	5/152	250/9376	1.23368421052632	ATP6V1B1/IDS/CTSV/LAPTM4A/CTSH	0.480736310764803
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	6/152	308/9376	1.20164046479836	GPX3/NDUFA13/NDUFA7/PSMA2/TUBB6/PSMD9	0.461896931796182
Metabolism	Lipid metabolism	hsa00591	Linoleic acid metabolism	1/152	30/9376	2.05614035087719	CYP2J2	0.743733184501956
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	1/152	30/9376	2.05614035087719	FOLR1	0.743733184501956
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	3/152	138/9376	1.34096109839817	NDUFA13/NDUFA7/ATP6V1B1	0.517968299123417
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	3/152	140/9376	1.3218045112782	SERPINE1/KLF2/CALM2	0.492449803841386
Metabolism	Metabolism of other amino acids	hsa00410	beta-Alanine metabolism	1/152	31/9376	1.98981324278438	CNDP2	0.70858546422305
NA	NA	hsa04981	Folate transport and metabolism	1/152	31/9376	1.98981324278438	FOLR1	0.70858546422305
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	3/152	142/9376	1.30318754633062	MID1/UBE2L6/UBC	0.467313557151892
Metabolism	Carbohydrate metabolism	hsa00052	Galactose metabolism	1/152	32/9376	1.92763157894737	UGP2	0.674732895540305
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	1/152	32/9376	1.92763157894737	LDHA	0.674732895540305
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	2/152	87/9376	1.41802782819117	TPM1/TPM4	0.502838038617915
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	3/152	144/9376	1.28508771929825	KLF4/ID3/SKIL	0.442547246369754
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	2/152	89/9376	1.38616203429923	TUBB6/PDGFA	0.469866669811129
Organismal Systems	Environmental adaptation	hsa04710	Circadian rhythm	1/152	34/9376	1.81424148606811	BHLHE40	0.610549019642645
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	2/152	90/9376	1.37076023391813	FOS/JUN	0.453678133546209
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	3/152	148/9376	1.25035561877667	GADD45A/FOS/JUN	0.394078001996068
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	2/152	91/9376	1.3556969346443	FOS/JUN	0.437680955273888
Metabolism	Carbohydrate metabolism	hsa00040	Pentose and glucuronate interconversions	1/152	36/9376	1.71345029239766	UGP2	0.550540556572674
Metabolism	Carbohydrate metabolism	hsa00500	Starch and sucrose metabolism	1/152	36/9376	1.71345029239766	UGP2	0.550540556572674
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	2/152	93/9376	1.32654216185625	JUN/CALM2	0.406241556697938
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	2/152	93/9376	1.32654216185625	FN1/GADD45A	0.406241556697938
Metabolism	Amino acid metabolism	hsa00350	Tyrosine metabolism	1/152	37/9376	1.66714082503556	MIF	0.52193446668529
Metabolism	Global and overview maps	hsa01250	Biosynthesis of nucleotide sugars	1/152	37/9376	1.66714082503556	UGP2	0.52193446668529
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	1/152	37/9376	1.66714082503556	GADD45A	0.52193446668529
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	4/152	214/9376	1.15297589768815	FOS/B2M/JUN/CALM2	0.290591253522762
Metabolism	Carbohydrate metabolism	hsa00520	Amino sugar and nucleotide sugar metabolism	1/152	38/9376	1.62326869806094	UGP2	0.494183185756164
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	2/152	97/9376	1.27183939229517	FOS/CALM2	0.345458159938168
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	2/152	98/9376	1.25886143931257	NR4A1/CALM2	0.330674724491973
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	2/152	99/9376	1.2461456671983	FOS/JUN	0.316048548056263
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	2/152	99/9376	1.2461456671983	CYP2J2/CALM2	0.316048548056263
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	2/152	99/9376	1.2461456671983	KRT19/KRT18	0.316048548056263
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	1/152	42/9376	1.46867167919799	AOC1	0.390757428384437
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	2/152	105/9376	1.1749373433584	JUN/UBC	0.231399102920468
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	1/152	44/9376	1.40191387559809	KRTCAP2	0.343020249242941
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	2/152	106/9376	1.16385302879841	FOLR1/PDGFA	0.217778661504347
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	3/152	170/9376	1.08854489164087	GADD45A/ACTG1/HMOX1	0.1495547706783
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	2/152	109/9376	1.13182037662965	FOS/JUN	0.177694506098511
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	2/152	109/9376	1.13182037662965	SLC27A6/TRIB3	0.177694506098511
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	1/152	47/9376	1.31243001119821	PKM	0.275633444168148
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	4/152	238/9376	1.03670942061035	EFNA1/RAP1B/PDGFA/CALM2	0.0736356655871787
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	1/152	50/9376	1.23368421052632	SDC1	0.212674025162947
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	2/152	115/9376	1.07276887871854	DUSP1/CYP2J2	0.100789071906809
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	1/152	51/9376	1.20949432404541	LPCAT1	0.192566489695709
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	1/152	52/9376	1.18623481781377	CYP2J2	0.17286584874784
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	3/152	184/9376	1.00572082379863	EFNA1/EFNB1/SEMA4A	0.0100602844504943
Metabolism	Glycan biosynthesis and metabolism	hsa00510	N-Glycan biosynthesis	1/152	56/9376	1.1015037593985	KRTCAP2	0.0977948466195218
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	1/152	56/9376	1.1015037593985	EEF1G	0.0977948466195218
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	2/152	125/9376	0.986947368421053	SPTSSA/PPP2R2B	-0.0188584732868347
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	5/152	323/9376	0.954863940035848	TIMP3/TPM1/EFNA1/PDGFA/HMOX1	-0.105968413358593
Metabolism	Global and overview maps	hsa01212	Fatty acid metabolism	1/152	57/9376	1.08217913204063	SCD	0.0798844238016541
Organismal Systems	Immune system	hsa04611	Platelet activation	2/152	126/9376	0.979114452798663	ACTG1/RAP1B	-0.0302975875757276
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/152	59/9376	1.04549509366637	GPX3	0.0449987351559595
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	1/152	59/9376	1.04549509366637	GADD45A	0.0449987351559595
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	2/152	130/9376	0.948987854251012	FOS/JUN	-0.0751823867019582
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	5/152	333/9376	0.926189347241979	FN1/PKM/ATP6V1B1/PPP2R2B/ITGB6	-0.176048643256725
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	3/152	201/9376	0.920659858601728	GADD45A/NR4A3/PDGFA	-0.145960636114609
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	1/152	63/9376	0.979114452798663	GADD45A	-0.0213510440495082
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	3/152	205/9376	0.902695763799743	GADD45A/B2M/JUN	-0.180820687769747
Human Diseases	Infectious disease: viral	hsa05162	Measles	2/152	136/9376	0.907120743034056	FOS/JUN	-0.140055441206969
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	1/152	65/9376	0.948987854251012	NR4A1	-0.0529760888608649
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	2/152	138/9376	0.89397406559878	YWHAZ/CALM2	-0.161068442009295
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	2/152	138/9376	0.89397406559878	FLOT1/CALM2	-0.161068442009295
Metabolism	Metabolism of cofactors and vitamins	hsa00830	Retinol metabolism	1/152	68/9376	0.907120743034056	RDH13	-0.0986717399421421
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/152	69/9376	0.89397406559878	CALM2	-0.113469615180764
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	2/152	143/9376	0.862716231137284	ACTN4/ACTN1	-0.212355532119119
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	2/152	144/9376	0.85672514619883	PSMA2/PSMD9	-0.22240835971403
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	1/152	70/9376	0.881203007518797	CBR1	-0.128062131754834
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	1/152	70/9376	0.881203007518797	ACTG1	-0.128062131754834
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	3/152	217/9376	0.852777104050449	KLF4/FOS/JUN	-0.281662466930354
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	1/152	71/9376	0.868791697553744	FOS	-0.142455784051067
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	1/152	73/9376	0.844989185291997	GADD45A	-0.170670988339556
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	2/152	149/9376	0.827975980219004	NDUFA13/NDUFA7	-0.27170632649186
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	1/152	75/9376	0.822456140350877	GPX3	-0.198161486471252
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	2/152	154/9376	0.801093643198906	UGP2/RDH13	-0.319480421961732
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	1/152	77/9376	0.801093643198906	GADD45A	-0.224969522548439
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/152	77/9376	0.801093643198906	GADD45A	-0.224969522548439
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	2/152	155/9376	0.795925297113752	NR4A1/RAP1B	-0.328862077482147
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	1/152	78/9376	0.790823211875843	TPI1	-0.238129832036724
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	1/152	79/9376	0.780812791472352	CBR1	-0.251133772665817
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	1/152	79/9376	0.780812791472352	ATP6V1B1	-0.251133772665817
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	2/152	158/9376	0.780812791472352	GADD45A/YWHAZ	-0.356675420824824
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	2/152	158/9376	0.780812791472352	ATP6V1B1/STRADB	-0.356675420824824
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/152	80/9376	0.771052631578947	PDGFA	-0.2639856848374
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	3/152	235/9376	0.787458006718925	NDUFA13/NDUFA7/ACTG1	-0.423574308874611
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	1/152	82/9376	0.752246469833119	B2M	-0.289249907330143
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/152	86/9376	0.717258261933905	JUN	-0.338126397180692
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	2/152	168/9376	0.734335839598997	FTH1/CAPN2	-0.446018363782706
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	2/152	168/9376	0.734335839598997	CSH1/PDGFA	-0.446018363782706
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	1/152	88/9376	0.700956937799043	SERPINE1	-0.361794323842737
Human Diseases	Substance dependence	hsa05032	Morphine addiction	1/152	91/9376	0.677848467322152	PDE4C	-0.396403726971635
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	3/152	250/9376	0.740210526315789	TFRC/FOLR1/CAV2	-0.534440186922312
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/152	93/9376	0.663271080928127	CALM2	-0.418914603527336
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	2/152	181/9376	0.681593486478627	PLK3/CALM2	-0.555255857922639
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/152	98/9376	0.629430719656283	CALM2	-0.473372530911745
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	1/152	100/9376	0.616842105263158	TFRC	-0.494475972648684
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/152	101/9376	0.610734757686295	CALM2	-0.504890431121459
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	2/152	187/9376	0.65972417675204	GBP1/JUN	-0.603344774770974
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	1/152	102/9376	0.604747162022704	RAP1B	-0.515215976865723
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	1/152	103/9376	0.59887583035258	PPP2R2B	-0.525454479290952
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	1/152	104/9376	0.593117408906883	LPCAT1	-0.535607749098197
Human Diseases	Substance dependence	hsa05034	Alcoholism	2/152	191/9376	0.645907963626343	FOSB/CALM2	-0.634659883691416
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	1/152	105/9376	0.587468671679198	GADD45A	-0.545677540697837
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	1/152	115/9376	0.536384439359268	FOS	-0.642134149947157
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	2/152	205/9376	0.601797175866496	NDUFA13/NDUFA7	-0.739981231479888
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/152	122/9376	0.505608283002589	ACTG1	-0.705560304177566
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	1/152	128/9376	0.481907894736842	PDE4C	-0.757592791728982
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	2/152	227/9376	0.543473220496174	B2M/CALM2	-0.89379960381698
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	1/152	144/9376	0.428362573099415	SCD	-0.887363965797815
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/152	149/9376	0.413987990109502	PDGFA	-0.925586849383974
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	1/152	150/9376	0.411228070175439	GADD45A	-0.93311202434359
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	2/152	254/9376	0.485702445089101	PDGFA/CALM2	-1.06667979547647
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	1/152	157/9376	0.392893060677171	DUSP5	-0.984738461399941
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	1/152	166/9376	0.371591629676601	CALM2	-1.0486099519242
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	1/152	169/9376	0.364995328558082	UBC	-1.069323191647
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	1/152	173/9376	0.356556130209918	ACTG1	-1.09652059535578
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	1/152	178/9376	0.346540508574808	JUN	-1.12987332087247
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	1/152	180/9376	0.342690058479532	B2M	-1.14302244132889
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	2/152	298/9376	0.413987990109502	CSH1/EBI3	-1.31967607887322
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	1/152	193/9376	0.319607308426507	RAP1B	-1.22600936436347
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	1/152	195/9376	0.316329284750337	ACTG1	-1.23841748323068
NA	NA	hsa04081	Hormone signaling	1/152	219/9376	0.281663061763999	CSH1	-1.38077029265108
Genetic Information Processing	Transcription	hsa03040	Spliceosome	1/152	243/9376	0.253844487762616	HNRNPA1	-1.51277223397732
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	1/152	370/9376	0.166714082503556	CSH1	-2.09931069388495
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	1/152	449/9376	0.137381315203376	CALM2	-2.40456792190899