category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	7/125	51/9376	10.2952156862745	KDELR2/ACTB/ATP6V1G1/ACTG1/ARF1/ATP6V1E1/SEC61G	7.73689038045309
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	9/125	169/9376	3.99450887573964	CTSL/RAB1A/TAX1BP1/GABARAP/MAP1LC3B/DAPK1/GABARAPL1/WIPI1/GORASP2	4.56621324689002
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	9/125	204/9376	3.30917647058824	FN1/CTSL/ACTB/EZR/ACTG1/TIMP3/CDKN1A/CAV2/PPP1CB	3.87602427670773
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	8/125	174/9376	3.44864367816092	XBP1/HERPUD1/SEC24D/KRTCAP2/UBE2D3/SSR1/HSPA5/SEC61G	3.78970501058676
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	5/125	78/9376	4.80820512820513	FN1/ACTB/ACTG1/ACTR3/CAV2	3.92571862278586
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	9/125	232/9376	2.90979310344828	FN1/ACTN4/ACTB/GSN/EZR/ACTG1/C9/ACTR3/PPP1CB	3.42380095459439
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	7/125	155/9376	3.38745806451613	CTSL/ACTB/ATP6V1G1/ACTG1/CLEC7A/ATP6V1E1/SEC61G	3.4838455594539
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	8/125	200/9376	3.00032	RAB1A/ACTB/SEC24D/EZR/ACTG1/ARF1/ACTR3/FOS	3.3237938263937
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	8/125	203/9376	2.9559802955665	FN1/FLNB/ACTN4/ACTB/ACTG1/FLT1/CAV2/PPP1CB	3.27493814593512
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	9/125	253/9376	2.66826877470356	ACTN4/ACTB/RIPK2/MAP1LC3B/ACTG1/WIPI1/ARF1/UBE2D3/ACTR3	3.12682624453305
Cellular Processes	Transport and catabolism	hsa04136	Autophagy - other	3/125	32/9376	7.032	GABARAP/GABARAPL1/WIPI1	3.9729784680823
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	5/125	95/9376	3.94778947368421	CTSL/ATP6V1G1/FLT1/ATP6V1E1/FOS	3.35665869336247
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	6/125	138/9376	3.26121739130435	FN1/ACTB/ACTG1/ACTR3/FOS/SKAP2	3.11056431575242
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	5/125	105/9376	3.57180952380952	BNIP3L/TAX1BP1/GABARAP/MAP1LC3B/GABARAPL1	3.08046631030745
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	5/125	110/9376	3.40945454545455	EPAS1/LDHA/FLT1/CDKN1A/EIF4E	2.95471254843161
NA	NA	hsa04518	Integrin signaling	6/125	154/9376	2.92238961038961	FN1/FLNB/ACTN4/ACTB/ACTG1/FLT1	2.79598937259882
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	8/125	248/9376	2.41961290322581	ACTB/RHOB/RIPK2/ACTG1/ARF1/ACTR3/SNX9/FOS	2.63362700661018
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	5/125	116/9376	3.23310344827586	ACTN4/ACTB/CD99/EZR/ACTG1	2.81305774791897
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	5/125	119/9376	3.15159663865546	JUNB/TNFAIP3/MAP3K8/FOS/CREB3L2	2.74565211900516
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	5/125	122/9376	3.07409836065574	CSH1/IGFBP3/JUNB/FOS/CREB3L2	2.68034575586064
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	10/125	368/9376	2.03826086956522	XBP1/RAB1A/GPX3/NDUFA7/ACTB/MAP1LC3B/ACTG1/WIPI1/COX6C/HSPA5	2.36190546614768
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	5/125	137/9376	2.73751824817518	CTSL/ACTB/CTSH/ACTG1/FOS	2.38135135963274
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	5/125	138/9376	2.71768115942029	NDUFA7/ATP6V1G1/COX6C/COX17/ATP6V1E1	2.36286778125786
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	3/125	56/9376	4.01828571428571	RAB1A/ARF1/EEF1G	2.63325374031719
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	6/125	187/9376	2.40667379679144	GABARAP/RIPK2/MAP1LC3B/GABARAPL1/TNFAIP3/GBP2	2.25853268169171
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	5/125	142/9376	2.64112676056338	CTSL/ACTB/ACTG1/CAV2/FOS	2.29053888307289
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	4/125	103/9376	2.91293203883495	FN1/SERPINB9/ACTN4/C9	2.26910361504134
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	7/125	250/9376	2.100224	CTSL/ATP6V1G1/LGMN/GM2A/CTSH/IDS/ATP6V1E1	2.04954373750762
Organismal Systems	Excretory system	hsa04966	Collecting duct acid secretion	2/125	28/9376	5.35771428571429	ATP6V1G1/ATP6V1E1	2.68426086884785
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	5/125	154/9376	2.43532467532467	ACTB/ACTG1/CDKN1A/FOS/PPP1CB	2.08758542844148
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	3/125	66/9376	3.40945454545455	CYP11A1/DHRS9/CYP19A1	2.28329575489797
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	3/125	67/9376	3.3585671641791	BPGM/PGM2/LDHA	2.25206249697342
Genetic Information Processing	Folding, sorting and degradation	hsa03060	Protein export	2/125	31/9376	4.83922580645161	HSPA5/SEC61G	2.488749320462
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	3/125	69/9376	3.26121739130435	FOS/PPP1CB/CREB3L2	2.19133265027221
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	4/125	115/9376	2.60897391304348	CDKN1A/FOS/PDE4C/CREB3L2	2.01797269276983
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	5/125	170/9376	2.20611764705882	ACTN4/ACTB/EZR/ACTG1/ACTR3	1.84469661752704
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	3/125	75/9376	3.00032	GPX3/HSPA5/CREB3L2	2.02167616521714
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	3/125	76/9376	2.96084210526316	ACTB/EZR/ACTG1	1.99505213886736
Metabolism	Global and overview maps	hsa01250	Biosynthesis of nucleotide sugars	2/125	37/9376	4.05448648648649	PGM2/NANS	2.16389003357905
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	6/125	233/9376	1.9315364806867	FN1/ACTB/TPM4/FHL2/CSRP1/ACTG1	1.6737083091356
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	6/125	235/9376	1.91509787234043	NDUFA7/ACTB/ACTG1/COX6C/COX17/CREB3L2	1.65139485227775
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	3/125	82/9376	2.74419512195122	CTSL/LGMN/HSPA5	1.84394075773342
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	6/125	238/9376	1.89095798319328	RPS26/RPS4Y1/RPS29/RPL17/C9/FOS	1.61832755727019
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	2/125	41/9376	3.65892682926829	DAPK1/CDKN1A	1.98329564223208
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	2/125	42/9376	3.57180952380952	MAP1LC3B/PCBP1	1.9416719262684
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	3/125	87/9376	2.58648275862069	RALB/CDKN1A/FOS	1.72805199519882
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	2/125	44/9376	3.40945454545455	RAB11A/CREB3L2	1.86210435204359
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	3/125	93/9376	2.41961290322581	ACTN4/ACTB/ACTG1	1.59923962298237
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	5/125	201/9376	1.86587064676617	IGFBP3/FLT1/CDKN1A/NFKBIZ/REL	1.44242856288865
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	5/125	205/9376	1.82946341463415	ACTN4/GSN/CDKN1A/REL/CREB3L2	1.39576441973296
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	3/125	98/9376	2.29616326530612	MARCKS/GSN/ACTR3	1.49931148191981
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	3/125	99/9376	2.2729696969697	ACTB/TPM4/ACTG1	1.48005613897209
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	2/125	52/9376	2.88492307692308	CYP11A1/CYP19A1	1.58431113698335
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	4/125	157/9376	1.91103184713376	IGFBP3/ZFP36L1/CDKN1A/PPP1CB	1.33809756965408
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	4/125	157/9376	1.91103184713376	ACTB/WWC1/ACTG1/PPP1CB	1.33809756965408
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	4/125	157/9376	1.91103184713376	XBP1/NDUFA7/COX6C/FOS	1.33809756965408
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	6/125	275/9376	1.63653818181818	NDUFA7/C9/COX6C/HSPA5/CAV2/CREB3L2	1.24535323503073
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	3/125	104/9376	2.16369230769231	LPCAT1/LYPLA1/GDPD5	1.38712125310539
Metabolism	Amino acid metabolism	hsa00270	Cysteine and methionine metabolism	2/125	54/9376	2.77807407407407	CDO1/LDHA	1.52313530364974
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	3/125	105/9376	2.14308571428571	ACTB/TPM4/ACTG1	1.36916711756903
NA	NA	hsa04519	Cadherin signaling	8/125	404/9376	1.48530693069307	KRT19/ACTN4/ACTB/WWC1/ACTG1/ACTR3/PPP1CB/KRT8	1.15906781863202
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	3/125	109/9376	2.06444036697248	PPP1R3B/PPP1CB/CREB3L2	1.2993055923659
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	3/125	110/9376	2.04567272727273	INHBA/ID3/GREM2	1.2823077881482
Metabolism	Amino acid metabolism	hsa00360	Phenylalanine metabolism	1/125	16/9376	4.688	MIF	1.71616596014958
Metabolism	Metabolism of other amino acids	hsa00430	Taurine and hypotaurine metabolism	1/125	17/9376	4.41223529411765	CDO1	1.63679772228329
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	3/125	117/9376	1.92328205128205	ACTB/ACTG1/SMARCA1	1.16813109820424
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	2/125	65/9376	2.30793846153846	CYP11A1/CREB3L2	1.22996323520836
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	3/125	122/9376	1.84445901639344	RAB2A/SCD/CREB3L2	1.09128968207314
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	3/125	122/9376	1.84445901639344	ACTB/ACTG1/DIO2	1.09128968207314
Metabolism	Glycan biosynthesis and metabolism	hsa00531	Glycosaminoglycan degradation	1/125	19/9376	3.94778947368421	IDS	1.49503463401349
Metabolism	Metabolism of cofactors and vitamins	hsa00830	Retinol metabolism	2/125	68/9376	2.20611764705882	RDH13/DHRS9	1.1602785006477
Metabolism	Glycan biosynthesis and metabolism	hsa00541	Biosynthesis of various nucleotide sugars	1/125	20/9376	3.7504	NANS	1.43123864727813
Organismal Systems	Immune system	hsa04611	Platelet activation	3/125	126/9376	1.78590476190476	ACTB/ACTG1/PPP1CB	1.03235872040472
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	2/125	70/9376	2.14308571428571	EPAS1/CDKN1A	1.11581603271631
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	2/125	70/9376	2.14308571428571	ACTB/ACTG1	1.11581603271631
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	5/125	250/9376	1.50016	DAB2/RAB11A/ARF1/ACTR3/CAV2	0.931719173324534
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	2/125	71/9376	2.1129014084507	ATP6V1G1/ATP6V1E1	1.09414273718065
Metabolism	Amino acid metabolism	hsa00340	Histidine metabolism	1/125	22/9376	3.40945454545455	AOC1	1.31515729891177
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	3/125	133/9376	1.69190977443609	GABARAP/GABARAPL1/CDKN1A	0.934146764681264
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	3/125	133/9376	1.69190977443609	FOS/PPP1CB/CREB3L2	0.934146764681264
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	2/125	75/9376	2.00021333333333	IGFBP3/CDKN1A	1.01089198534854
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	4/125	196/9376	1.53077551020408	MAP1LC3B/CDKN1A/ZFP36/FOS	0.872898758409395
Organismal Systems	Endocrine system	hsa04614	Renin-angiotensin system	1/125	23/9376	3.26121739130435	LNPEP	1.26205148470121
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	2/125	76/9376	1.97389473684211	PLIN2/SCD	0.990885891604079
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	2/125	77/9376	1.94825974025974	RALB/CDKN1A	0.971182516042297
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	3/125	138/9376	1.63060869565217	PPP1R3B/EIF4E/PPP1CB	0.867474712268749
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	3/125	139/9376	1.61887769784173	KRT19/FOS/CREB3L2	0.854462613313612
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	2/125	79/9376	1.89893670886076	ATP6V1G1/ATP6V1E1	0.932647541986389
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	6/125	333/9376	1.3514954954955	FN1/ATP6V1G1/MAML2/CDKN1A/ATP6V1E1/CREB3L2	0.759157556657807
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	3/125	142/9376	1.58467605633803	FHL2/JUNB/FOS	0.816038878425351
Genetic Information Processing	Chromosome	hsa03083	Polycomb repressive complex	2/125	83/9376	1.80742168674699	RYBP/UBE2D3	0.85883115768908
Metabolism	Lipid metabolism	hsa01040	Biosynthesis of unsaturated fatty acids	1/125	27/9376	2.77807407407407	SCD	1.07546295643704
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	8/125	480/9376	1.25013333333333	XBP1/RAB1A/GPX3/NDUFA7/MAP1LC3B/WIPI1/COX6C/HSPA5	0.653944823665743
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	4/125	212/9376	1.41524528301887	ACTB/RALB/ACTG1/FLT1	0.710847437535874
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	2/125	86/9376	1.74437209302326	ACTB/ACTG1	0.806079275807471
Environmental Information Processing	Signal transduction	hsa04392	Hippo signaling pathway - multiple species	1/125	29/9376	2.58648275862069	WWC1	0.99459103094971
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	2/125	87/9376	1.72432183908046	TPM4/COX6C	0.78895644619377
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	2/125	88/9376	1.70472727272727	TFPI/C9	0.77205389055535
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	2/125	89/9376	1.68557303370787	GABARAP/GABARAPL1	0.755365789083715
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	3/125	154/9376	1.46119480519481	RDH13/RFK/MTHFD1L	0.670777540126798
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	3/125	154/9376	1.46119480519481	TPM4/PPP1CB/CREB3L2	0.670777540126798
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	2/125	90/9376	1.66684444444444	EIF4E/CREB3L2	0.738886542357152
Metabolism	Carbohydrate metabolism	hsa00030	Pentose phosphate pathway	1/125	31/9376	2.41961290322581	PGM2	0.920253412103345
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	3/125	155/9376	1.45176774193548	CYP11A1/CDKN1A/CREB3L2	0.659232120152625
Genetic Information Processing	Translation	hsa03010	Ribosome	4/125	222/9376	1.3514954954955	RPS26/RPS4Y1/RPS29/RPL17	0.616079986976502
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	4/125	224/9376	1.33942857142857	CDKN1A/ZFP36/FOS/CREB3L2	0.597668963679034
Metabolism	Carbohydrate metabolism	hsa00052	Galactose metabolism	1/125	32/9376	2.344	PGM2	0.885225971668205
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	1/125	32/9376	2.344	LDHA	0.885225971668205
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	3/125	158/9376	1.42420253164557	ATP6V1G1/ATP6V1E1/EIF4E	0.625071577836835
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	6/125	362/9376	1.24322651933702	FN1/CSH1/FLT1/CDKN1A/EIF4E/CREB3L2	0.548596127414807
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	2/125	93/9376	1.6130752688172	MAML2/FOS	0.690649020965601
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	2/125	93/9376	1.6130752688172	FN1/CDKN1A	0.690649020965601
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	4/125	226/9376	1.32757522123894	FOS/PDE4C/PPP1CB/CREB3L2	0.57943005699549
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	2/125	94/9376	1.59591489361702	TNFAIP3/FOS	0.674953243674975
Genetic Information Processing	Folding, sorting and degradation	hsa04130	SNARE interactions in vesicular transport	1/125	33/9376	2.2729696969697	STX11	0.851487281043675
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	5/125	298/9376	1.25852348993289	GDF15/EBI3/INHBA/CSH1/INHA	0.527180523592415
NA	NA	hsa04517	IgSF CAM signaling	5/125	299/9376	1.2543143812709	ACTN4/ACTB/EZR/ACTG1/ACTR3	0.519495333242963
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	3/125	163/9376	1.38051533742331	CDKN1A/FOS/CREB3L2	0.569654768834466
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	2/125	98/9376	1.53077551020408	CYP11A1/CREB3L2	0.613964180340257
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	2/125	99/9376	1.51531313131313	CDKN1A/FOS	0.599144162903894
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	2/125	99/9376	1.51531313131313	LYPLA1/FOS	0.599144162903894
Metabolism	Carbohydrate metabolism	hsa00500	Starch and sucrose metabolism	1/125	36/9376	2.08355555555556	PGM2	0.757138446527047
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	3/125	168/9376	1.33942857142857	CSH1/PIM1/CDKN1A	0.516020180190315
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	2/125	101/9376	1.48530693069307	FN1/PIM1	0.569989066993702
Metabolism	Amino acid metabolism	hsa00350	Tyrosine metabolism	1/125	37/9376	2.02724324324324	MIF	0.727729988641188
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	1/125	37/9376	2.02724324324324	CDKN1A	0.727729988641188
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	5/125	308/9376	1.21766233766234	GPX3/NDUFA7/WIPI1/COX6C/CREB3L2	0.451491102234152
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	3/125	170/9376	1.32367058823529	ACTB/ACTG1/CDKN1A	0.495037976408544
Metabolism	Carbohydrate metabolism	hsa00520	Amino sugar and nucleotide sugar metabolism	1/125	38/9376	1.97389473684211	PGM2	0.699235044912313
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	3/125	173/9376	1.30071676300578	RAB11A/ACTB/ACTG1	0.464047334747646
Metabolism	Metabolism of cofactors and vitamins	hsa00670	One carbon pool by folate	1/125	39/9376	1.92328205128205	MTHFD1L	0.671597887248713
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	2/125	106/9376	1.41524528301887	CDKN1A/CREB3L2	0.499762974244459
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	2/125	107/9376	1.40201869158879	LDHA/CREB3L2	0.486147433985425
Metabolism	Amino acid metabolism	hsa00260	Glycine, serine and threonine metabolism	1/125	41/9376	1.82946341463415	BPGM	0.618697422406146
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	2/125	109/9376	1.37629357798165	MAP3K8/FOS	0.459321503968833
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	2/125	109/9376	1.37629357798165	EBI3/FOS	0.459321503968833
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	1/125	42/9376	1.78590476190476	AOC1	0.593344568788582
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	5/125	323/9376	1.16111455108359	MARCKS/EZR/TIMP3/PIM1/CDKN1A	0.342520106799191
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	1/125	44/9376	1.70472727272727	KRTCAP2	0.544636014829532
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	2/125	115/9376	1.30448695652174	FOS/CREB3L2	0.381887088773988
Metabolism	Carbohydrate metabolism	hsa00620	Pyruvate metabolism	1/125	47/9376	1.59591489361702	LDHA	0.476060256727748
Metabolism	Amino acid metabolism	hsa00280	Valine, leucine and isoleucine degradation	1/125	48/9376	1.56266666666667	HIBADH	0.454280235002718
Cellular Processes	Cell motility	hsa04814	Motor proteins	3/125	194/9376	1.1599175257732	ACTB/TPM4/ACTG1	0.261622196039884
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	4/125	268/9376	1.1195223880597	XBP1/NDUFA7/COX6C/HSPA5	0.230755176373481
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	1/125	49/9376	1.53077551020408	CREB3L2	0.432996346901493
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	3/125	195/9376	1.15396923076923	ACTB/ACTG1/CLEC7A	0.252553014260796
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	2/125	122/9376	1.2296393442623	MAP3K8/FOS	0.296761645179385
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	1/125	50/9376	1.50016	AOC1	0.412185354996759
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	1/125	51/9376	1.47074509803922	LPCAT1	0.391825573885612
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	1/125	53/9376	1.41524528301887	RAB11A	0.352379881107824
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	2/125	128/9376	1.172	PGM2/PDE4C	0.227748657386258
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	3/125	205/9376	1.09767804878049	NDUFA7/COX6C/PPP1CB	0.164365953544653
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	2/125	130/9376	1.15396923076923	FOS/CREB3L2	0.205482563849656
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	1/125	55/9376	1.36378181818182	GM2A	0.314512118690559
Metabolism	Glycan biosynthesis and metabolism	hsa00510	N-Glycan biosynthesis	1/125	56/9376	1.33942857142857	KRTCAP2	0.296128875756988
Metabolism	Global and overview maps	hsa01212	Fatty acid metabolism	1/125	57/9376	1.3159298245614	SCD	0.278092772892664
Human Diseases	Infectious disease: viral	hsa05162	Measles	2/125	136/9376	1.10305882352941	TNFAIP3/FOS	0.14072295729646
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	1/125	59/9376	1.27132203389831	UPP1	0.24300730345768
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	1/125	59/9376	1.27132203389831	GPX3	0.24300730345768
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	1/125	59/9376	1.27132203389831	CDKN1A	0.24300730345768
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	3/125	216/9376	1.04177777777778	XBP1/HSPA5/FOS	0.0722055829254439
NA	NA	hsa04382	Cornified envelope formation	3/125	217/9376	1.03697695852535	KRT19/COL17A1/KRT8	0.0640594680270745
Environmental Information Processing	Signal transduction	hsa04330	Notch signaling pathway	1/125	62/9376	1.2098064516129	MAML2	0.192660583346311
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	2/125	143/9376	1.04906293706294	ACTN4/C9	0.0687221041042331
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	1/125	63/9376	1.19060317460317	CDKN1A	0.176441973722651
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	2/125	144/9376	1.04177777777778	INHBA/ID3	0.0587252653558282
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	2/125	144/9376	1.04177777777778	XBP1/WIPI1	0.0587252653558282
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	3/125	227/9376	0.991295154185022	NDUFA7/COX6C/FOS	-0.0154324010876562
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	2/125	148/9376	1.01362162162162	CDKN1A/FOS	0.0194156610369333
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	2/125	149/9376	1.00681879194631	RALB/ARF1	0.00975251479126268
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	1/125	67/9376	1.1195223880597	PPP1CB	0.114125173870825
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	1/125	68/9376	1.10305882352941	PIM1	0.0991420178079772
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	1/125	71/9376	1.05645070422535	FOS	0.0554991911843179
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	1/125	71/9376	1.05645070422535	LDHA	0.0554991911843179
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	3/125	238/9376	0.945478991596639	RALB/FLT1/REL	-0.099031438085424
Human Diseases	Cancer: specific types	hsa05218	Melanoma	1/125	73/9376	1.02750684931507	CDKN1A	0.0274243960499172
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	1/125	73/9376	1.02750684931507	CDKN1A	0.0274243960499172
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	1/125	75/9376	1.00010666666667	CDKN1A	0.000107805479934744
Human Diseases	Cancer: specific types	hsa05214	Glioma	1/125	76/9376	0.986947368421053	CDKN1A	-0.0132803556591986
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/125	77/9376	0.97412987012987	CDKN1A	-0.0264955019715714
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	1/125	78/9376	0.961641025641026	IMPA2	-0.039542654589871
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	1/125	78/9376	0.961641025641026	FOS	-0.039542654589871
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/125	78/9376	0.961641025641026	FOS	-0.039542654589871
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	2/125	166/9376	0.903710843373494	PPP1CB/CREB3L2	-0.145494948787263
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/125	80/9376	0.9376	EIF4E	-0.0651520116858769
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	1/125	82/9376	0.914731707317073	UPP1	-0.0901445476148905
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	1/125	83/9376	0.903710843373494	PCBP1	-0.102419998392192
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	1/125	85/9376	0.882447058823529	UPP1	-0.126548801568729
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	1/125	86/9376	0.872186046511628	CDKN1A	-0.138409513241623
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/125	86/9376	0.872186046511628	CREB3L2	-0.138409513241623
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	2/125	180/9376	0.833422222222222	SRSF9/PPP1CB	-0.262301116735047
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	1/125	89/9376	0.842786516853933	FN1	-0.173218141485173
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	2/125	181/9376	0.828817679558011	RIPK2/CLEC7A	-0.270314059059158
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	1/125	90/9376	0.833422222222222	FOS	-0.184573897677593
Genetic Information Processing	Translation	hsa03008	Ribosome biogenesis in eukaryotes	2/125	183/9376	0.81975956284153	REXO2/RRP7A	-0.286217016983826
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/125	91/9376	0.824263736263736	FOS	-0.195811157710069
Human Diseases	Substance dependence	hsa05032	Morphine addiction	1/125	91/9376	0.824263736263736	PDE4C	-0.195811157710069
Human Diseases	Substance dependence	hsa05034	Alcoholism	2/125	191/9376	0.785424083769633	PPP1CB/CREB3L2	-0.348260631467231
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	1/125	97/9376	0.773278350515464	FOS	-0.260900298850402
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/125	98/9376	0.765387755102041	IMPA2	-0.271383121239296
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/125	99/9376	0.757656565656566	PPP1CB	-0.281767813164306
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	1/125	99/9376	0.757656565656566	KRT19	-0.281767813164306
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/125	101/9376	0.742653465346535	CREB3L2	-0.302251424622578
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	1/125	102/9376	0.735372549019608	RAB11A	-0.312354478947804
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	1/125	103/9376	0.728233009708738	PPP1CB	-0.322367678307265
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	1/125	103/9376	0.728233009708738	COL17A1	-0.322367678307265
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	1/125	103/9376	0.728233009708738	FOS	-0.322367678307265
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	1/125	105/9376	0.714361904761905	TNFAIP3	-0.342132075169386
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/125	105/9376	0.714361904761905	CLEC7A	-0.342132075169386
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	2/125	205/9376	0.731785365853658	CDKN1A/TNFAIP3	-0.451333279549501
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	4/125	388/9376	0.773278350515464	XBP1/NDUFA7/WIPI1/COX6C	-0.530180350267011
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	3/125	300/9376	0.75008	FLT1/MAP3K8/FOS	-0.511399972311407
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	2/125	217/9376	0.69131797235023	FOS/CREB3L2	-0.534765628903983
NA	NA	hsa04081	Hormone signaling	2/125	219/9376	0.685004566210046	CSH1/DIO2	-0.548271931292179
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	1/125	120/9376	0.625066666666667	RIPK2	-0.480484416973163
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	2/125	227/9376	0.660863436123348	CDKN1A/CREB3L2	-0.601238848852291
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	1/125	134/9376	0.559761194029851	PPP1CB	-0.596628566123063
Genetic Information Processing	Transcription	hsa03040	Spliceosome	2/125	243/9376	0.617349794238683	SRSF9/PCBP1	-0.702497306468653
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	1/125	138/9376	0.543536231884058	PPP1CB	-0.627918356720365
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	1/125	140/9376	0.535771428571429	MAP1LC3B	-0.643280261997171
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	1/125	142/9376	0.528225352112676	UBE2D3	-0.65846112622219
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	1/125	144/9376	0.520888888888889	SCD	-0.673466340995562
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	1/125	149/9376	0.503409395973154	NDUFA7	-0.710244167751089
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	1/125	150/9376	0.500053333333333	CDKN1A	-0.71747849046633
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	1/125	156/9376	0.480820512820513	CDKN1A	-0.760082385310411
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	1/125	157/9376	0.477757961783439	GULP1	-0.76705419718019
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	1/125	158/9376	0.47473417721519	CDKN1A	-0.773990516648284
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	1/125	160/9376	0.4688	CD99	-0.787758556081793
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/125	168/9376	0.44647619047619	TNFAIP3	-0.841500922353006
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/125	184/9376	0.407652173913043	SEMA4C	-0.94325041908036
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	1/125	214/9376	0.350504672897196	FOS	-1.11720810573906
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	1/125	254/9376	0.295307086614173	FLT1	-1.32348198061625
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	1/125	370/9376	0.202724324324324	CSH1	-1.81881995015234