ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 45/368 175/18639 0.257142857142857 13.0241459627329 1.95290202382648e-37 1.36898431870236e-34 GO:0045296 cadherin binding 24/368 334/18639 0.0718562874251497 3.63948190575371 5.71267544531086e-08 2.00229274358146e-05 GO:0003779 actin binding 27/368 443/18639 0.0609480812641084 3.08698719206988 2.44511840383809e-07 5.71342667030168e-05 GO:0019843 rRNA binding 10/368 65/18639 0.153846153846154 7.79222408026756 5.43063203633904e-07 9.51718264368416e-05 GO:0048306 calcium-dependent protein binding 10/368 80/18639 0.125 6.33118206521739 3.84161629399344e-06 0.00053859460441788 GO:0004857 enzyme inhibitor activity 22/368 416/18639 0.0528846153846154 2.67857702759197 2.99321341868973e-05 0.00344299121381454 GO:0008135 translation factor activity, RNA binding 9/368 83/18639 0.108433734939759 5.49210974332111 3.7526288153031e-05 0.00344299121381454 GO:0180051 translation factor activity 9/368 84/18639 0.107142857142857 5.42672748447205 4.13085990739587e-05 0.00344299121381454 GO:1990948 ubiquitin ligase inhibitor activity 4/368 11/18639 0.363636363636364 18.4179841897233 4.4203881489773e-05 0.00344299121381454 GO:0055106 ubiquitin-protein transferase regulator activity 6/368 36/18639 0.166666666666667 8.44157608695652 6.71240453522915e-05 0.00470539557919564 GO:0051015 actin filament binding 14/368 209/18639 0.0669856459330144 3.39278656126482 7.38449048668571e-05 0.00470593439196971 GO:0140297 DNA-binding transcription factor binding 23/368 488/18639 0.0471311475409836 2.38716700819672 0.000114920662664006 0.00671328204395568 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 4/368 15/18639 0.266666666666667 13.5065217391304 0.000171737644416652 0.0085991491954338 GO:0055105 ubiquitin-protein transferase inhibitor activity 4/368 15/18639 0.266666666666667 13.5065217391304 0.000171737644416652 0.0085991491954338 GO:0003746 translation elongation factor activity 4/368 18/18639 0.222222222222222 11.2554347826087 0.000367358762405837 0.0171678994964328 GO:0061134 peptidase regulator activity 13/368 226/18639 0.0575221238938053 2.91346431319738 0.000581313217695767 0.0246100361206022 GO:0016860 intramolecular oxidoreductase activity 6/368 53/18639 0.113207547169811 5.73390073831009 0.000596819706205761 0.0246100361206022 GO:0001786 phosphatidylserine binding 6/368 59/18639 0.101694915254237 5.15079218865144 0.00106087058537802 0.0408671648522554 GO:0061135 endopeptidase regulator activity 11/368 184/18639 0.0597826086956522 3.02795663988658 0.00110766923280007 0.0408671648522554 GO:0008307 structural constituent of muscle 5/368 42/18639 0.119047619047619 6.02969720496894 0.0013626868384293 0.0462059722622825 GO:0004866 endopeptidase inhibitor activity 10/368 161/18639 0.062111801242236 3.14592897650554 0.00138420173681588 0.0462059722622825 GO:0004859 phospholipase inhibitor activity 3/368 12/18639 0.25 12.6623641304348 0.00147096406024144 0.0468702639195115 GO:0030414 peptidase inhibitor activity 10/368 169/18639 0.0591715976331361 2.99700926164137 0.0019853687721903 0.0605105873611044 GO:0072341 modified amino acid binding 7/368 91/18639 0.0769230769230769 3.89611204013378 0.00216020550038158 0.0630960023236453 GO:0016769 transferase activity, transferring nitrogenous groups 4/368 30/18639 0.133333333333333 6.75326086956522 0.00272992105502976 0.0765469863830343 GO:0031625 ubiquitin protein ligase binding 14/368 302/18639 0.0463576158940397 2.34798805067665 0.00284481373311698 0.0767005548813463 GO:0003743 translation initiation factor activity 5/368 51/18639 0.0980392156862745 4.96563299232737 0.00325667315648112 0.0845528845441951 GO:0043425 bHLH transcription factor binding 4/368 32/18639 0.125 6.33118206521739 0.00347293360559184 0.0853578347485015 GO:0055102 lipase inhibitor activity 3/368 16/18639 0.1875 9.49677309782609 0.00353120857019478 0.0853578347485015 GO:0005544 calcium-dependent phospholipid binding 5/368 53/18639 0.0943396226415094 4.77825061525841 0.00385307976391097 0.0880204387260762 GO:0098631 cell adhesion mediator activity 6/368 76/18639 0.0789473684210526 3.99864130434783 0.00389248730457683 0.0880204387260762 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 15/368 349/18639 0.0429799426934097 2.1769107387567 0.00415920759995072 0.0911126414864205 GO:0098632 cell-cell adhesion mediator activity 5/368 55/18639 0.0909090909090909 4.60449604743083 0.00452383392731266 0.0960971994862478 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 3/368 18/18639 0.166666666666667 8.44157608695652 0.00499737523055111 0.0975719366606933 GO:0098641 cadherin binding involved in cell-cell adhesion 3/368 18/18639 0.166666666666667 8.44157608695652 0.00499737523055111 0.0975719366606933 GO:0044389 ubiquitin-like protein ligase binding 14/368 322/18639 0.0434782608695652 2.20215028355388 0.0050108269897075 0.0975719366606933 GO:0002020 protease binding 8/368 136/18639 0.0588235294117647 2.97937979539642 0.00564652950397799 0.10512279911091 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 3/368 19/18639 0.157894736842105 7.99728260869565 0.00584848668377389 0.10512279911091 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 3/368 19/18639 0.157894736842105 7.99728260869565 0.00584848668377389 0.10512279911091 GO:0043531 ADP binding 4/368 38/18639 0.105263157894737 5.33152173913043 0.00649837129522865 0.113883956948882 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 6/368 86/18639 0.0697674418604651 3.53368301314459 0.00710862125084541 0.121540085288845 GO:0003714 transcription corepressor activity 10/368 204/18639 0.0490196078431373 2.48281649616368 0.00749299535150136 0.125061660509582 GO:1990841 promoter-specific chromatin binding 5/368 68/18639 0.0735294117647059 3.72422474424552 0.0110201774759443 0.179654521177604 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 3/368 27/18639 0.111111111111111 5.62771739130435 0.0157189936566427 0.245405921950714 GO:0005522 profilin binding 2/368 10/18639 0.2 10.1298913043478 0.0157535898541828 0.245405921950714 GO:0044325 transmembrane transporter binding 7/368 136/18639 0.0514705882352941 2.60695732097187 0.0184630258573132 0.272929472998843 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 2/368 11/18639 0.181818181818182 9.20899209486166 0.0190056005772897 0.272929472998843 GO:0050786 RAGE receptor binding 2/368 11/18639 0.181818181818182 9.20899209486166 0.0190056005772897 0.272929472998843 GO:0003785 actin monomer binding 3/368 29/18639 0.103448275862069 5.23959895052474 0.0190778090969234 0.272929472998843 GO:0017166 vinculin binding 2/368 12/18639 0.166666666666667 8.44157608695652 0.0225125278806993 0.301835600941038 GO:0035259 nuclear glucocorticoid receptor binding 2/368 12/18639 0.166666666666667 8.44157608695652 0.0225125278806993 0.301835600941038 GO:0097371 MDM2/MDM4 family protein binding 2/368 12/18639 0.166666666666667 8.44157608695652 0.0225125278806993 0.301835600941038 GO:1902936 phosphatidylinositol bisphosphate binding 6/368 111/18639 0.0540540540540541 2.73780846063455 0.0228206659769971 0.301835600941038 GO:0005200 structural constituent of cytoskeleton 6/368 112/18639 0.0535714285714286 2.71336374223602 0.0237266677059542 0.30800729744211 GO:0051059 NF-kappaB binding 3/368 32/18639 0.09375 4.74838654891304 0.0248018296097477 0.316110591935148 GO:0019855 calcium channel inhibitor activity 2/368 13/18639 0.153846153846154 7.79222408026756 0.0262630952089215 0.319523877712497 GO:0140666 annealing activity 2/368 13/18639 0.153846153846154 7.79222408026756 0.0262630952089215 0.319523877712497 GO:0071889 14-3-3 protein binding 3/368 33/18639 0.0909090909090909 4.60449604743083 0.0268928798645325 0.319523877712497 GO:0140416 transcription regulator inhibitor activity 3/368 33/18639 0.0909090909090909 4.60449604743083 0.0268928798645325 0.319523877712497 GO:0008376 acetylgalactosaminyltransferase activity 3/368 34/18639 0.0882352941176471 4.46906969309463 0.0290751692647928 0.330832859429059 GO:0015035 protein-disulfide reductase activity 3/368 34/18639 0.0882352941176471 4.46906969309463 0.0290751692647928 0.330832859429059 GO:0005545 1-phosphatidylinositol binding 2/368 14/18639 0.142857142857143 7.23563664596273 0.030246369808824 0.330832859429059 GO:0008191 metalloendopeptidase inhibitor activity 2/368 14/18639 0.142857142857143 7.23563664596273 0.030246369808824 0.330832859429059 GO:0044548 S100 protein binding 2/368 14/18639 0.142857142857143 7.23563664596273 0.030246369808824 0.330832859429059 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 4/368 60/18639 0.0666666666666667 3.37663043478261 0.0306763707031224 0.330832859429059 GO:0005523 tropomyosin binding 2/368 15/18639 0.133333333333333 6.75326086956522 0.0344517536100617 0.355157048244901 GO:0051371 muscle alpha-actinin binding 2/368 15/18639 0.133333333333333 6.75326086956522 0.0344517536100617 0.355157048244901 GO:0140161 monocarboxylate:sodium symporter activity 2/368 15/18639 0.133333333333333 6.75326086956522 0.0344517536100617 0.355157048244901 GO:0042805 actinin binding 3/368 37/18639 0.0810810810810811 4.10671269095182 0.0361656201788676 0.367421735440379 GO:0003712 transcription coregulator activity 16/368 495/18639 0.0323232323232323 1.63715415019763 0.0375971382067748 0.37650848404213 GO:0004708 MAP kinase kinase activity 2/368 16/18639 0.125 6.33118206521739 0.0388689743300427 0.378432652852222 GO:0022841 potassium ion leak channel activity 2/368 16/18639 0.125 6.33118206521739 0.0388689743300427 0.378432652852222 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 10/368 268/18639 0.0373134328358209 1.88990509409474 0.0408173381665606 0.390957087527996 GO:0016776 phosphotransferase activity, phosphate group as acceptor 3/368 39/18639 0.0769230769230769 3.89611204013378 0.0413400363006124 0.390957087527996 GO:0004550 nucleoside diphosphate kinase activity 2/368 17/18639 0.117647058823529 5.95875959079284 0.0434880767981559 0.390957087527996 GO:0038191 neuropilin binding 2/368 17/18639 0.117647058823529 5.95875959079284 0.0434880767981559 0.390957087527996 GO:0004177 aminopeptidase activity 3/368 40/18639 0.075 3.79870923913043 0.0440593579382478 0.390957087527996 GO:0015036 disulfide oxidoreductase activity 3/368 40/18639 0.075 3.79870923913043 0.0440593579382478 0.390957087527996 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 3/368 40/18639 0.075 3.79870923913043 0.0440593579382478 0.390957087527996 GO:0004674 protein serine/threonine kinase activity 14/368 433/18639 0.0323325635103926 1.637626769756 0.049502056538179 0.4177773499897 GO:0008028 monocarboxylic acid transmembrane transporter activity 4/368 70/18639 0.0571428571428571 2.89425465838509 0.0496030532943781 0.4177773499897 GO:0097110 scaffold protein binding 4/368 70/18639 0.0571428571428571 2.89425465838509 0.0496030532943781 0.4177773499897 GO:0035198 miRNA binding 3/368 42/18639 0.0714285714285714 3.61781832298137 0.0497579080198855 0.4177773499897 GO:0001217 DNA-binding transcription repressor activity 10/368 278/18639 0.0359712230215827 1.82192289646544 0.0500617651913478 0.4177773499897 GO:0022840 leak channel activity 2/368 19/18639 0.105263157894737 5.33152173913043 0.0532936412953222 0.429411983310584 GO:0022842 narrow pore channel activity 2/368 19/18639 0.105263157894737 5.33152173913043 0.0532936412953222 0.429411983310584 GO:0070003 threonine-type peptidase activity 2/368 19/18639 0.105263157894737 5.33152173913043 0.0532936412953222 0.429411983310584 GO:0106310 protein serine kinase activity 12/368 361/18639 0.0332409972299169 1.68363844393593 0.0556418506640701 0.439475282327516 GO:0019205 nucleobase-containing compound kinase activity 3/368 44/18639 0.0681818181818182 3.45337203557312 0.0557964338475734 0.439475282327516 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 15/368 484/18639 0.0309917355371901 1.56971456162415 0.0579926421605881 0.445452761993301 GO:0042288 MHC class I protein binding 2/368 20/18639 0.1 5.06494565217391 0.0584617034285075 0.445452761993301 GO:0043024 ribosomal small subunit binding 2/368 20/18639 0.1 5.06494565217391 0.0584617034285075 0.445452761993301 GO:0043021 ribonucleoprotein complex binding 7/368 177/18639 0.0395480225988701 2.00308585114223 0.0620452617967338 0.466898271477221 GO:0046982 protein heterodimerization activity 12/368 369/18639 0.032520325203252 1.64713679745493 0.0634256276668115 0.466898271477221 GO:0072542 protein phosphatase activator activity 2/368 21/18639 0.0952380952380952 4.82375776397515 0.0637948316205373 0.466898271477221 GO:0001216 DNA-binding transcription activator activity 15/368 491/18639 0.0305498981670061 1.54733573895333 0.0639404194890346 0.466898271477221 GO:0016853 isomerase activity 7/368 180/18639 0.0388888888888889 1.96970108695652 0.0666218230182306 0.481462865317316 GO:0046332 SMAD binding 4/368 79/18639 0.0506329113924051 2.56452944413869 0.0710386943287186 0.504031519963893 GO:0043022 ribosome binding 5/368 112/18639 0.0446428571428571 2.26113645186335 0.0711827681546725 0.504031519963893 GO:0000049 tRNA binding 4/368 80/18639 0.05 2.53247282608696 0.0736712252246452 0.50991002604607 GO:1901981 phosphatidylinositol phosphate binding 7/368 185/18639 0.0378378378378378 1.91646592244418 0.0746905348801998 0.50991002604607 GO:0004602 glutathione peroxidase activity 2/368 23/18639 0.0869565217391304 4.40430056710775 0.0749225858527036 0.50991002604607 GO:0099186 structural constituent of postsynapse 2/368 23/18639 0.0869565217391304 4.40430056710775 0.0749225858527036 0.50991002604607 GO:0015294 solute:monoatomic cation symporter activity 5/368 116/18639 0.0431034482758621 2.18316622938531 0.0800099226981544 0.528704865046375 GO:0015295 solute:proton symporter activity 2/368 24/18639 0.0833333333333333 4.22078804347826 0.0807010279029416 0.528704865046375 GO:0048027 mRNA 5'-UTR binding 2/368 24/18639 0.0833333333333333 4.22078804347826 0.0807010279029416 0.528704865046375 GO:0050699 WW domain binding 2/368 24/18639 0.0833333333333333 4.22078804347826 0.0807010279029416 0.528704865046375 GO:0004860 protein kinase inhibitor activity 4/368 84/18639 0.0476190476190476 2.41187888198758 0.0846863972286862 0.547220990324238 GO:0008483 transaminase activity 2/368 25/18639 0.08 4.05195652173913 0.0866121536556541 0.547220990324238 GO:0019211 phosphatase activator activity 2/368 25/18639 0.08 4.05195652173913 0.0866121536556541 0.547220990324238 GO:0000287 magnesium ion binding 8/368 230/18639 0.0347826086956522 1.7617202268431 0.0866498287104 0.547220990324238 GO:0050660 flavin adenine dinucleotide binding 4/368 86/18639 0.0465116279069767 2.35578867542973 0.0904788067255533 0.563002824797236 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 3/368 54/18639 0.0555555555555556 2.81385869565217 0.0907550915864303 0.563002824797236 GO:0008374 O-acyltransferase activity 3/368 55/18639 0.0545454545454545 2.7626976284585 0.0946555732451711 0.579943673449197 GO:0008017 microtubule binding 9/368 276/18639 0.0326086956521739 1.65161271266541 0.0976908926030155 0.579943673449197 GO:0170055 lipid transmembrane transporter activity 3/368 56/18639 0.0535714285714286 2.71336374223602 0.0986237444288766 0.579943673449197 GO:0004683 calcium/calmodulin-dependent protein kinase activity 2/368 27/18639 0.0740740740740741 3.7518115942029 0.0988028661835987 0.579943673449197 GO:0003727 single-stranded RNA binding 4/368 89/18639 0.0449438202247191 2.27638006839277 0.0995123832026178 0.579943673449197 GO:0019001 guanyl nucleotide binding 12/368 400/18639 0.03 1.51948369565217 0.100174926786124 0.579943673449197 GO:0032561 guanyl ribonucleotide binding 12/368 400/18639 0.03 1.51948369565217 0.100174926786124 0.579943673449197 GO:0016829 lyase activity 7/368 200/18639 0.035 1.77273097826087 0.102187683949971 0.579943673449197 GO:0019210 kinase inhibitor activity 4/368 90/18639 0.0444444444444444 2.25108695652174 0.102613419123798 0.579943673449197 GO:0016504 peptidase activator activity 3/368 57/18639 0.0526315789473684 2.66576086956522 0.1026580569397 0.579943673449197 GO:0030246 carbohydrate binding 9/368 280/18639 0.0321428571428571 1.62801824534161 0.104314771071543 0.579943673449197 GO:0005242 inward rectifier potassium channel activity 2/368 28/18639 0.0714285714285714 3.61781832298137 0.105068254676245 0.579943673449197 GO:0051393 alpha-actinin binding 2/368 28/18639 0.0714285714285714 3.61781832298137 0.105068254676245 0.579943673449197 GO:0097718 disordered domain specific binding 2/368 28/18639 0.0714285714285714 3.61781832298137 0.105068254676245 0.579943673449197 GO:0061980 regulatory RNA binding 3/368 58/18639 0.0517241379310345 2.61979947526237 0.106756945451114 0.584661084072118 GO:0005539 glycosaminoglycan binding 8/368 242/18639 0.0330578512396694 1.67436219906576 0.107736605814994 0.585452408343496 GO:0043236 laminin binding 2/368 29/18639 0.0689655172413793 3.49306596701649 0.111437917311751 0.596320458286544 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 2/368 29/18639 0.0689655172413793 3.49306596701649 0.111437917311751 0.596320458286544 GO:0005543 phospholipid binding 14/368 497/18639 0.028169014084507 1.4267452541335 0.117092107696876 0.612170580813759 GO:0001968 fibronectin binding 2/368 30/18639 0.0666666666666667 3.37663043478261 0.117905322755335 0.612170580813759 GO:0035925 mRNA 3'-UTR AU-rich region binding 2/368 30/18639 0.0666666666666667 3.37663043478261 0.117905322755335 0.612170580813759 GO:0098918 structural constituent of synapse 2/368 30/18639 0.0666666666666667 3.37663043478261 0.117905322755335 0.612170580813759 GO:0004867 serine-type endopeptidase inhibitor activity 4/368 95/18639 0.0421052631578947 2.13260869565217 0.118766332369003 0.612170580813759 GO:0005179 hormone activity 5/368 132/18639 0.0378787878787879 1.91854001976285 0.120752167194748 0.617551720595197 GO:0003924 GTPase activity 10/368 331/18639 0.0302114803625378 1.53019506107973 0.121572236008755 0.617551720595197 GO:0008201 heparin binding 6/368 172/18639 0.0348837209302326 1.7668415065723 0.125962633949114 0.635250405743371 GO:0005507 copper ion binding 3/368 63/18639 0.0476190476190476 2.41187888198758 0.128164321496822 0.641737066923374 GO:0005525 GTP binding 11/368 378/18639 0.0291005291005291 1.47392598343685 0.130238972751906 0.647500141128271 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 2/368 33/18639 0.0606060606060606 3.06966403162055 0.137831886917105 0.669975386502115 GO:0015631 tubulin binding 11/368 385/18639 0.0285714285714286 1.44712732919255 0.142226210720214 0.669975386502115 GO:0005343 organic acid:sodium symporter activity 2/368 35/18639 0.0571428571428571 2.89425465838509 0.151494685941099 0.669975386502115 GO:0019888 protein phosphatase regulator activity 4/368 107/18639 0.0373831775700935 1.8934376269809 0.16154226605375 0.669975386502115 GO:0015293 symporter activity 5/368 146/18639 0.0342465753424658 1.73457042882668 0.162872381888901 0.669975386502115 GO:0019209 kinase activator activity 5/368 148/18639 0.0337837837837838 1.71113028789659 0.169322401324383 0.669975386502115 GO:0000146 microfilament motor activity 2/368 38/18639 0.0526315789473684 2.66576086956522 0.172448145521623 0.669975386502115 GO:0004222 metalloendopeptidase activity 4/368 110/18639 0.0363636363636364 1.84179841897233 0.173015985950307 0.669975386502115 GO:0005126 cytokine receptor binding 8/368 275/18639 0.0290909090909091 1.47343873517787 0.17854707204689 0.669975386502115 GO:0004175 endopeptidase activity 11/368 405/18639 0.0271604938271605 1.37566425120773 0.179518903641507 0.669975386502115 GO:0048029 monosaccharide binding 3/368 74/18639 0.0405405405405405 2.05335634547591 0.179809454106635 0.669975386502115 GO:0004382 GDP phosphatase activity 1/368 10/18639 0.1 5.06494565217391 0.180826363044257 0.669975386502115 GO:0005131 growth hormone receptor binding 1/368 10/18639 0.1 5.06494565217391 0.180826363044257 0.669975386502115 GO:0005337 nucleoside transmembrane transporter activity 1/368 10/18639 0.1 5.06494565217391 0.180826363044257 0.669975386502115 GO:0005345 purine nucleobase transmembrane transporter activity 1/368 10/18639 0.1 5.06494565217391 0.180826363044257 0.669975386502115 GO:0005528 FK506 binding 1/368 10/18639 0.1 5.06494565217391 0.180826363044257 0.669975386502115 GO:0008140 cAMP response element binding protein binding 1/368 10/18639 0.1 5.06494565217391 0.180826363044257 0.669975386502115 GO:0008239 dipeptidyl-peptidase activity 1/368 10/18639 0.1 5.06494565217391 0.180826363044257 0.669975386502115 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/368 10/18639 0.1 5.06494565217391 0.180826363044257 0.669975386502115 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 1/368 10/18639 0.1 5.06494565217391 0.180826363044257 0.669975386502115 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/368 10/18639 0.1 5.06494565217391 0.180826363044257 0.669975386502115 GO:0030957 Tat protein binding 1/368 10/18639 0.1 5.06494565217391 0.180826363044257 0.669975386502115 GO:0031434 mitogen-activated protein kinase kinase binding 1/368 10/18639 0.1 5.06494565217391 0.180826363044257 0.669975386502115 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/368 10/18639 0.1 5.06494565217391 0.180826363044257 0.669975386502115 GO:0032052 bile acid binding 1/368 10/18639 0.1 5.06494565217391 0.180826363044257 0.669975386502115 GO:0032356 oxidized DNA binding 1/368 10/18639 0.1 5.06494565217391 0.180826363044257 0.669975386502115 GO:0035256 G protein-coupled glutamate receptor binding 1/368 10/18639 0.1 5.06494565217391 0.180826363044257 0.669975386502115 GO:0043295 glutathione binding 1/368 10/18639 0.1 5.06494565217391 0.180826363044257 0.669975386502115 GO:0051880 G-quadruplex DNA binding 1/368 10/18639 0.1 5.06494565217391 0.180826363044257 0.669975386502115 GO:0098505 G-rich strand telomeric DNA binding 1/368 10/18639 0.1 5.06494565217391 0.180826363044257 0.669975386502115 GO:0003725 double-stranded RNA binding 3/368 75/18639 0.04 2.02597826086957 0.184759633685961 0.669975386502115 GO:0061791 GTPase motor activity 2/368 40/18639 0.05 2.53247282608696 0.186665370997334 0.669975386502115 GO:0071949 FAD binding 2/368 40/18639 0.05 2.53247282608696 0.186665370997334 0.669975386502115 GO:1990606 membrane scission GTPase motor activity 2/368 40/18639 0.05 2.53247282608696 0.186665370997334 0.669975386502115 GO:0001221 transcription coregulator binding 4/368 115/18639 0.0347826086956522 1.7617202268431 0.192733428435373 0.669975386502115 GO:0001530 lipopolysaccharide binding 2/368 41/18639 0.0487804878048781 2.4707051961824 0.19383458863133 0.669975386502115 GO:0016877 ligase activity, forming carbon-sulfur bonds 2/368 41/18639 0.0487804878048781 2.4707051961824 0.19383458863133 0.669975386502115 GO:0042287 MHC protein binding 2/368 41/18639 0.0487804878048781 2.4707051961824 0.19383458863133 0.669975386502115 GO:0005536 D-glucose binding 1/368 11/18639 0.0909090909090909 4.60449604743083 0.197008439290954 0.669975386502115 GO:0008172 S-methyltransferase activity 1/368 11/18639 0.0909090909090909 4.60449604743083 0.197008439290954 0.669975386502115 GO:0008199 ferric iron binding 1/368 11/18639 0.0909090909090909 4.60449604743083 0.197008439290954 0.669975386502115 GO:0008432 JUN kinase binding 1/368 11/18639 0.0909090909090909 4.60449604743083 0.197008439290954 0.669975386502115 GO:0010854 adenylate cyclase regulator activity 1/368 11/18639 0.0909090909090909 4.60449604743083 0.197008439290954 0.669975386502115 GO:0015205 nucleobase transmembrane transporter activity 1/368 11/18639 0.0909090909090909 4.60449604743083 0.197008439290954 0.669975386502115 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/368 11/18639 0.0909090909090909 4.60449604743083 0.197008439290954 0.669975386502115 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/368 11/18639 0.0909090909090909 4.60449604743083 0.197008439290954 0.669975386502115 GO:0019215 intermediate filament binding 1/368 11/18639 0.0909090909090909 4.60449604743083 0.197008439290954 0.669975386502115 GO:0042608 T cell receptor binding 1/368 11/18639 0.0909090909090909 4.60449604743083 0.197008439290954 0.669975386502115 GO:0045294 alpha-catenin binding 1/368 11/18639 0.0909090909090909 4.60449604743083 0.197008439290954 0.669975386502115 GO:0047676 arachidonate-CoA ligase activity 1/368 11/18639 0.0909090909090909 4.60449604743083 0.197008439290954 0.669975386502115 GO:0070697 activin receptor binding 1/368 11/18639 0.0909090909090909 4.60449604743083 0.197008439290954 0.669975386502115 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/368 11/18639 0.0909090909090909 4.60449604743083 0.197008439290954 0.669975386502115 GO:1900750 oligopeptide binding 1/368 11/18639 0.0909090909090909 4.60449604743083 0.197008439290954 0.669975386502115 GO:0019208 phosphatase regulator activity 4/368 117/18639 0.0341880341880342 1.73160535117057 0.200810775016655 0.669975386502115 GO:0042056 chemoattractant activity 2/368 42/18639 0.0476190476190476 2.41187888198758 0.201038422661902 0.669975386502115 GO:0051879 Hsp90 protein binding 2/368 42/18639 0.0476190476190476 2.41187888198758 0.201038422661902 0.669975386502115 GO:0015370 solute:sodium symporter activity 3/368 79/18639 0.0379746835443038 1.92339708310402 0.204901087283235 0.669975386502115 GO:0016835 carbon-oxygen lyase activity 3/368 79/18639 0.0379746835443038 1.92339708310402 0.204901087283235 0.669975386502115 GO:0004712 protein serine/threonine/tyrosine kinase activity 2/368 43/18639 0.0465116279069767 2.35578867542973 0.208272726286637 0.669975386502115 GO:0008200 ion channel inhibitor activity 2/368 43/18639 0.0465116279069767 2.35578867542973 0.208272726286637 0.669975386502115 GO:0048156 tau protein binding 2/368 43/18639 0.0465116279069767 2.35578867542973 0.208272726286637 0.669975386502115 GO:0019207 kinase regulator activity 8/368 287/18639 0.0278745644599303 1.41183154067566 0.208418123165743 0.669975386502115 GO:0000340 RNA 7-methylguanosine cap binding 1/368 12/18639 0.0833333333333333 4.22078804347826 0.212871703964613 0.669975386502115 GO:0003995 acyl-CoA dehydrogenase activity 1/368 12/18639 0.0833333333333333 4.22078804347826 0.212871703964613 0.669975386502115 GO:0005078 MAP-kinase scaffold activity 1/368 12/18639 0.0833333333333333 4.22078804347826 0.212871703964613 0.669975386502115 GO:0005527 macrolide binding 1/368 12/18639 0.0833333333333333 4.22078804347826 0.212871703964613 0.669975386502115 GO:0008179 adenylate cyclase binding 1/368 12/18639 0.0833333333333333 4.22078804347826 0.212871703964613 0.669975386502115 GO:0010853 cyclase activator activity 1/368 12/18639 0.0833333333333333 4.22078804347826 0.212871703964613 0.669975386502115 GO:0016208 AMP binding 1/368 12/18639 0.0833333333333333 4.22078804347826 0.212871703964613 0.669975386502115 GO:0016840 carbon-nitrogen lyase activity 1/368 12/18639 0.0833333333333333 4.22078804347826 0.212871703964613 0.669975386502115 GO:0031543 peptidyl-proline dioxygenase activity 1/368 12/18639 0.0833333333333333 4.22078804347826 0.212871703964613 0.669975386502115 GO:0035497 cAMP response element binding 1/368 12/18639 0.0833333333333333 4.22078804347826 0.212871703964613 0.669975386502115 GO:0043047 single-stranded telomeric DNA binding 1/368 12/18639 0.0833333333333333 4.22078804347826 0.212871703964613 0.669975386502115 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/368 12/18639 0.0833333333333333 4.22078804347826 0.212871703964613 0.669975386502115 GO:0070008 serine-type exopeptidase activity 1/368 12/18639 0.0833333333333333 4.22078804347826 0.212871703964613 0.669975386502115 GO:0070410 co-SMAD binding 1/368 12/18639 0.0833333333333333 4.22078804347826 0.212871703964613 0.669975386502115 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/368 12/18639 0.0833333333333333 4.22078804347826 0.212871703964613 0.669975386502115 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/368 12/18639 0.0833333333333333 4.22078804347826 0.212871703964613 0.669975386502115 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/368 12/18639 0.0833333333333333 4.22078804347826 0.212871703964613 0.669975386502115 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/368 12/18639 0.0833333333333333 4.22078804347826 0.212871703964613 0.669975386502115 GO:0001223 transcription coactivator binding 2/368 44/18639 0.0454545454545455 2.30224802371542 0.215533502117069 0.669975386502115 GO:0016248 channel inhibitor activity 2/368 44/18639 0.0454545454545455 2.30224802371542 0.215533502117069 0.669975386502115 GO:0030547 signaling receptor inhibitor activity 2/368 44/18639 0.0454545454545455 2.30224802371542 0.215533502117069 0.669975386502115 GO:0008083 growth factor activity 5/368 162/18639 0.0308641975308642 1.56325483091787 0.217031780726191 0.669975386502115 GO:0042605 peptide antigen binding 2/368 45/18639 0.0444444444444444 2.25108695652174 0.222816897922354 0.669975386502115 GO:0141110 transporter inhibitor activity 2/368 45/18639 0.0444444444444444 2.25108695652174 0.222816897922354 0.669975386502115 GO:0005516 calmodulin binding 6/368 207/18639 0.0289855072463768 1.46810018903592 0.226292154655 0.669975386502115 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/368 13/18639 0.0769230769230769 3.89611204013378 0.228422421360921 0.669975386502115 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/368 13/18639 0.0769230769230769 3.89611204013378 0.228422421360921 0.669975386502115 GO:0005035 death receptor activity 1/368 13/18639 0.0769230769230769 3.89611204013378 0.228422421360921 0.669975386502115 GO:0030955 potassium ion binding 1/368 13/18639 0.0769230769230769 3.89611204013378 0.228422421360921 0.669975386502115 GO:0031432 titin binding 1/368 13/18639 0.0769230769230769 3.89611204013378 0.228422421360921 0.669975386502115 GO:0031994 insulin-like growth factor I binding 1/368 13/18639 0.0769230769230769 3.89611204013378 0.228422421360921 0.669975386502115 GO:0051011 microtubule minus-end binding 1/368 13/18639 0.0769230769230769 3.89611204013378 0.228422421360921 0.669975386502115 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/368 13/18639 0.0769230769230769 3.89611204013378 0.228422421360921 0.669975386502115 GO:0071837 HMG box domain binding 1/368 13/18639 0.0769230769230769 3.89611204013378 0.228422421360921 0.669975386502115 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/368 13/18639 0.0769230769230769 3.89611204013378 0.228422421360921 0.669975386502115 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/368 13/18639 0.0769230769230769 3.89611204013378 0.228422421360921 0.669975386502115 GO:0001784 phosphotyrosine residue binding 2/368 47/18639 0.0425531914893617 2.15529602220167 0.237436841545287 0.687781925302671 GO:0043495 protein-membrane adaptor activity 2/368 47/18639 0.0425531914893617 2.15529602220167 0.237436841545287 0.687781925302671 GO:0140359 ABC-type transporter activity 2/368 47/18639 0.0425531914893617 2.15529602220167 0.237436841545287 0.687781925302671 GO:0019887 protein kinase regulator activity 7/368 255/18639 0.0274509803921569 1.39037723785166 0.240454026740476 0.68889482512249 GO:0016209 antioxidant activity 3/368 86/18639 0.0348837209302326 1.7668415065723 0.241226815618061 0.68889482512249 GO:0004705 JUN kinase activity 1/368 14/18639 0.0714285714285714 3.61781832298137 0.243666733018775 0.68889482512249 GO:0098847 sequence-specific single stranded DNA binding 1/368 14/18639 0.0714285714285714 3.61781832298137 0.243666733018775 0.68889482512249 GO:1901612 cardiolipin binding 1/368 14/18639 0.0714285714285714 3.61781832298137 0.243666733018775 0.68889482512249 GO:0001222 transcription corepressor binding 2/368 49/18639 0.0408163265306122 2.06732475598935 0.252104487507219 0.68889482512249 GO:0016763 pentosyltransferase activity 2/368 49/18639 0.0408163265306122 2.06732475598935 0.252104487507219 0.68889482512249 GO:0000774 adenyl-nucleotide exchange factor activity 1/368 15/18639 0.0666666666666667 3.37663043478261 0.258610660119397 0.68889482512249 GO:0004467 long-chain fatty acid-CoA ligase activity 1/368 15/18639 0.0666666666666667 3.37663043478261 0.258610660119397 0.68889482512249 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/368 15/18639 0.0666666666666667 3.37663043478261 0.258610660119397 0.68889482512249 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/368 15/18639 0.0666666666666667 3.37663043478261 0.258610660119397 0.68889482512249 GO:0031386 protein tag activity 1/368 15/18639 0.0666666666666667 3.37663043478261 0.258610660119397 0.68889482512249 GO:0033130 acetylcholine receptor binding 1/368 15/18639 0.0666666666666667 3.37663043478261 0.258610660119397 0.68889482512249 GO:0042809 nuclear vitamin D receptor binding 1/368 15/18639 0.0666666666666667 3.37663043478261 0.258610660119397 0.68889482512249 GO:0050780 dopamine receptor binding 1/368 15/18639 0.0666666666666667 3.37663043478261 0.258610660119397 0.68889482512249 GO:0061578 K63-linked deubiquitinase activity 1/368 15/18639 0.0666666666666667 3.37663043478261 0.258610660119397 0.68889482512249 GO:0120283 protein serine/threonine kinase binding 1/368 15/18639 0.0666666666666667 3.37663043478261 0.258610660119397 0.68889482512249 GO:0141047 molecular tag activity 1/368 15/18639 0.0666666666666667 3.37663043478261 0.258610660119397 0.68889482512249 GO:0031072 heat shock protein binding 4/368 131/18639 0.0305343511450382 1.54654829074013 0.259799562461525 0.68889482512249 GO:0016830 carbon-carbon lyase activity 2/368 51/18639 0.0392156862745098 1.98625319693095 0.266793834106894 0.68889482512249 GO:0051087 protein-folding chaperone binding 4/368 134/18639 0.0298507462686567 1.51192407527579 0.272875333244373 0.68889482512249 GO:0004707 MAP kinase activity 1/368 16/18639 0.0625 3.1655910326087 0.273260105838687 0.68889482512249 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/368 16/18639 0.0625 3.1655910326087 0.273260105838687 0.68889482512249 GO:0005521 lamin binding 1/368 16/18639 0.0625 3.1655910326087 0.273260105838687 0.68889482512249 GO:0015378 sodium:chloride symporter activity 1/368 16/18639 0.0625 3.1655910326087 0.273260105838687 0.68889482512249 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/368 16/18639 0.0625 3.1655910326087 0.273260105838687 0.68889482512249 GO:0016722 oxidoreductase activity, acting on metal ions 1/368 16/18639 0.0625 3.1655910326087 0.273260105838687 0.68889482512249 GO:0017070 U6 snRNA binding 1/368 16/18639 0.0625 3.1655910326087 0.273260105838687 0.68889482512249 GO:0043023 ribosomal large subunit binding 1/368 16/18639 0.0625 3.1655910326087 0.273260105838687 0.68889482512249 GO:0097027 ubiquitin-protein transferase activator activity 1/368 16/18639 0.0625 3.1655910326087 0.273260105838687 0.68889482512249 GO:0140328 floppase activity 1/368 16/18639 0.0625 3.1655910326087 0.273260105838687 0.68889482512249 GO:0051219 phosphoprotein binding 3/368 93/18639 0.032258064516129 1.63385343618513 0.278501240395042 0.68889482512249 GO:0005246 calcium channel regulator activity 2/368 53/18639 0.0377358490566038 1.91130024610336 0.281480829526137 0.68889482512249 GO:0051020 GTPase binding 8/368 315/18639 0.0253968253968254 1.28633540372671 0.284610157110767 0.68889482512249 GO:0016922 nuclear receptor binding 4/368 137/18639 0.0291970802919708 1.4788162488099 0.286060512380841 0.68889482512249 GO:0005092 GDP-dissociation inhibitor activity 1/368 17/18639 0.0588235294117647 2.97937979539642 0.28762085765372 0.68889482512249 GO:0008429 phosphatidylethanolamine binding 1/368 17/18639 0.0588235294117647 2.97937979539642 0.28762085765372 0.68889482512249 GO:0008484 sulfuric ester hydrolase activity 1/368 17/18639 0.0588235294117647 2.97937979539642 0.28762085765372 0.68889482512249 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/368 17/18639 0.0588235294117647 2.97937979539642 0.28762085765372 0.68889482512249 GO:0015278 intracellularly gated calcium channel activity 1/368 17/18639 0.0588235294117647 2.97937979539642 0.28762085765372 0.68889482512249 GO:0017110 nucleoside diphosphate phosphatase activity 1/368 17/18639 0.0588235294117647 2.97937979539642 0.28762085765372 0.68889482512249 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/368 17/18639 0.0588235294117647 2.97937979539642 0.28762085765372 0.68889482512249 GO:0030548 acetylcholine receptor regulator activity 1/368 17/18639 0.0588235294117647 2.97937979539642 0.28762085765372 0.68889482512249 GO:0031489 myosin V binding 1/368 17/18639 0.0588235294117647 2.97937979539642 0.28762085765372 0.68889482512249 GO:0048038 quinone binding 1/368 17/18639 0.0588235294117647 2.97937979539642 0.28762085765372 0.68889482512249 GO:0051787 misfolded protein binding 1/368 17/18639 0.0588235294117647 2.97937979539642 0.28762085765372 0.68889482512249 GO:1990226 histone methyltransferase binding 1/368 17/18639 0.0588235294117647 2.97937979539642 0.28762085765372 0.68889482512249 GO:0003925 G protein activity 2/368 54/18639 0.037037037037037 1.87590579710145 0.288816434831511 0.68889482512249 GO:0017069 snRNA binding 2/368 54/18639 0.037037037037037 1.87590579710145 0.288816434831511 0.68889482512249 GO:0016407 acetyltransferase activity 3/368 96/18639 0.03125 1.58279551630435 0.294652097595996 0.68889482512249 GO:0030295 protein kinase activator activity 4/368 139/18639 0.0287769784172662 1.45753831717235 0.294901915168759 0.68889482512249 GO:0140313 molecular sequestering activity 2/368 55/18639 0.0363636363636364 1.84179841897233 0.296143259797033 0.68889482512249 GO:0008237 metallopeptidase activity 5/368 184/18639 0.0271739130434783 1.37634392722117 0.298760139159443 0.68889482512249 GO:0004713 protein tyrosine kinase activity 4/368 140/18639 0.0285714285714286 1.44712732919255 0.29933590194671 0.68889482512249 GO:1901681 sulfur compound binding 7/368 275/18639 0.0254545454545455 1.28925889328063 0.301327315922304 0.68889482512249 GO:0000400 four-way junction DNA binding 1/368 18/18639 0.0555555555555556 2.81385869565217 0.301698589604286 0.68889482512249 GO:0004706 JUN kinase kinase kinase activity 1/368 18/18639 0.0555555555555556 2.81385869565217 0.301698589604286 0.68889482512249 GO:0008525 phosphatidylcholine transporter activity 1/368 18/18639 0.0555555555555556 2.81385869565217 0.301698589604286 0.68889482512249 GO:0015373 monoatomic anion:sodium symporter activity 1/368 18/18639 0.0555555555555556 2.81385869565217 0.301698589604286 0.68889482512249 GO:0017075 syntaxin-1 binding 1/368 18/18639 0.0555555555555556 2.81385869565217 0.301698589604286 0.68889482512249 GO:0032393 MHC class I receptor activity 1/368 18/18639 0.0555555555555556 2.81385869565217 0.301698589604286 0.68889482512249 GO:0050811 GABA receptor binding 1/368 18/18639 0.0555555555555556 2.81385869565217 0.301698589604286 0.68889482512249 GO:0070064 proline-rich region binding 1/368 18/18639 0.0555555555555556 2.81385869565217 0.301698589604286 0.68889482512249 GO:0099602 neurotransmitter receptor regulator activity 1/368 18/18639 0.0555555555555556 2.81385869565217 0.301698589604286 0.68889482512249 GO:1901611 phosphatidylglycerol binding 1/368 18/18639 0.0555555555555556 2.81385869565217 0.301698589604286 0.68889482512249 GO:0030170 pyridoxal phosphate binding 2/368 56/18639 0.0357142857142857 1.80890916149068 0.303458797403261 0.690664340843137 GO:0004601 peroxidase activity 2/368 57/18639 0.0350877192982456 1.77717391304348 0.310760642511027 0.69988830386629 GO:0015932 nucleobase-containing compound transmembrane transporter activity 2/368 57/18639 0.0350877192982456 1.77717391304348 0.310760642511027 0.69988830386629 GO:0070279 vitamin B6 binding 2/368 57/18639 0.0350877192982456 1.77717391304348 0.310760642511027 0.69988830386629 GO:0005520 insulin-like growth factor binding 1/368 19/18639 0.0526315789473684 2.66576086956522 0.315498864510339 0.69988830386629 GO:0008301 DNA binding, bending 1/368 19/18639 0.0526315789473684 2.66576086956522 0.315498864510339 0.69988830386629 GO:0015245 fatty acid transmembrane transporter activity 1/368 19/18639 0.0526315789473684 2.66576086956522 0.315498864510339 0.69988830386629 GO:0031420 alkali metal ion binding 1/368 19/18639 0.0526315789473684 2.66576086956522 0.315498864510339 0.69988830386629 GO:0050145 nucleoside monophosphate kinase activity 1/368 19/18639 0.0526315789473684 2.66576086956522 0.315498864510339 0.69988830386629 GO:0004879 nuclear receptor activity 2/368 59/18639 0.0338983050847458 1.71693072955048 0.325314125994097 0.704711826696504 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 2/368 59/18639 0.0338983050847458 1.71693072955048 0.325314125994097 0.704711826696504 GO:0045309 protein phosphorylated amino acid binding 2/368 59/18639 0.0338983050847458 1.71693072955048 0.325314125994097 0.704711826696504 GO:0070888 E-box binding 2/368 59/18639 0.0338983050847458 1.71693072955048 0.325314125994097 0.704711826696504 GO:0008238 exopeptidase activity 3/368 102/18639 0.0294117647058824 1.48968989769821 0.327093677751148 0.704711826696504 GO:0000339 RNA cap binding 1/368 20/18639 0.05 2.53247282608696 0.329027136146225 0.704711826696504 GO:0005326 neurotransmitter transmembrane transporter activity 1/368 20/18639 0.05 2.53247282608696 0.329027136146225 0.704711826696504 GO:0010851 cyclase regulator activity 1/368 20/18639 0.05 2.53247282608696 0.329027136146225 0.704711826696504 GO:0016505 peptidase activator activity involved in apoptotic process 1/368 20/18639 0.05 2.53247282608696 0.329027136146225 0.704711826696504 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/368 20/18639 0.05 2.53247282608696 0.329027136146225 0.704711826696504 GO:0031418 L-ascorbic acid binding 1/368 20/18639 0.05 2.53247282608696 0.329027136146225 0.704711826696504 GO:0035091 phosphatidylinositol binding 7/368 284/18639 0.0246478873239437 1.24840209736681 0.329736774830889 0.704711826696504 GO:0098531 ligand-modulated transcription factor activity 2/368 60/18639 0.0333333333333333 1.6883152173913 0.332561436645304 0.70858834981264 GO:0008236 serine-type peptidase activity 5/368 194/18639 0.0257731958762887 1.30539836396235 0.33750494700103 0.714120281881337 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/368 21/18639 0.0476190476190476 2.41187888198758 0.342288751372509 0.714120281881337 GO:0005123 death receptor binding 1/368 21/18639 0.0476190476190476 2.41187888198758 0.342288751372509 0.714120281881337 GO:0015125 bile acid transmembrane transporter activity 1/368 21/18639 0.0476190476190476 2.41187888198758 0.342288751372509 0.714120281881337 GO:0035613 RNA stem-loop binding 1/368 21/18639 0.0476190476190476 2.41187888198758 0.342288751372509 0.714120281881337 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/368 21/18639 0.0476190476190476 2.41187888198758 0.342288751372509 0.714120281881337 GO:0061891 calcium ion sensor activity 1/368 21/18639 0.0476190476190476 2.41187888198758 0.342288751372509 0.714120281881337 GO:0016758 hexosyltransferase activity 5/368 197/18639 0.0253807106598985 1.28551920105937 0.349220899071741 0.724004521833141 GO:0017171 serine hydrolase activity 5/368 198/18639 0.0252525252525253 1.2790266798419 0.353131728473421 0.724004521833141 GO:0015377 chloride:monoatomic cation symporter activity 1/368 22/18639 0.0454545454545455 2.30224802371542 0.355288952226249 0.724004521833141 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/368 22/18639 0.0454545454545455 2.30224802371542 0.355288952226249 0.724004521833141 GO:0033691 sialic acid binding 1/368 22/18639 0.0454545454545455 2.30224802371542 0.355288952226249 0.724004521833141 GO:0061133 endopeptidase activator activity 1/368 22/18639 0.0454545454545455 2.30224802371542 0.355288952226249 0.724004521833141 GO:0140517 protein-RNA adaptor activity 1/368 22/18639 0.0454545454545455 2.30224802371542 0.355288952226249 0.724004521833141 GO:0140784 metal ion sensor activity 1/368 22/18639 0.0454545454545455 2.30224802371542 0.355288952226249 0.724004521833141 GO:0003774 cytoskeletal motor activity 4/368 153/18639 0.0261437908496732 1.32416879795396 0.357458728636192 0.726314692098465 GO:0035402 histone H3T11 kinase activity 6/368 247/18639 0.0242914979757085 1.23035117056856 0.362013211367667 0.726735344950201 GO:0004386 helicase activity 4/368 155/18639 0.0258064516129032 1.30708274894811 0.366428937333398 0.726735344950201 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/368 23/18639 0.0434782608695652 2.20215028355388 0.368032877970501 0.726735344950201 GO:0005283 amino acid:sodium symporter activity 1/368 23/18639 0.0434782608695652 2.20215028355388 0.368032877970501 0.726735344950201 GO:0016849 phosphorus-oxygen lyase activity 1/368 23/18639 0.0434782608695652 2.20215028355388 0.368032877970501 0.726735344950201 GO:0017134 fibroblast growth factor binding 1/368 23/18639 0.0434782608695652 2.20215028355388 0.368032877970501 0.726735344950201 GO:0042171 lysophosphatidic acid acyltransferase activity 1/368 23/18639 0.0434782608695652 2.20215028355388 0.368032877970501 0.726735344950201 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/368 23/18639 0.0434782608695652 2.20215028355388 0.368032877970501 0.726735344950201 GO:0071617 lysophospholipid acyltransferase activity 1/368 23/18639 0.0434782608695652 2.20215028355388 0.368032877970501 0.726735344950201 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/368 23/18639 0.0434782608695652 2.20215028355388 0.368032877970501 0.726735344950201 GO:0140658 ATP-dependent chromatin remodeler activity 4/368 158/18639 0.0253164556962025 1.28226472206935 0.379871253989012 0.729430861550686 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/368 24/18639 0.0416666666666667 2.11039402173913 0.380525567103873 0.729430861550686 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/368 24/18639 0.0416666666666667 2.11039402173913 0.380525567103873 0.729430861550686 GO:0015149 hexose transmembrane transporter activity 1/368 24/18639 0.0416666666666667 2.11039402173913 0.380525567103873 0.729430861550686 GO:0019957 C-C chemokine binding 1/368 24/18639 0.0416666666666667 2.11039402173913 0.380525567103873 0.729430861550686 GO:0030215 semaphorin receptor binding 1/368 24/18639 0.0416666666666667 2.11039402173913 0.380525567103873 0.729430861550686 GO:0035035 histone acetyltransferase binding 1/368 24/18639 0.0416666666666667 2.11039402173913 0.380525567103873 0.729430861550686 GO:0055056 D-glucose transmembrane transporter activity 1/368 24/18639 0.0416666666666667 2.11039402173913 0.380525567103873 0.729430861550686 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/368 24/18639 0.0416666666666667 2.11039402173913 0.380525567103873 0.729430861550686 GO:0050840 extracellular matrix binding 2/368 67/18639 0.0298507462686567 1.51192407527579 0.382563891768195 0.729430861550686 GO:0003707 nuclear steroid receptor activity 1/368 25/18639 0.04 2.02597826086957 0.392771959330882 0.729430861550686 GO:0004709 MAP kinase kinase kinase activity 1/368 25/18639 0.04 2.02597826086957 0.392771959330882 0.729430861550686 GO:0015271 outward rectifier potassium channel activity 1/368 25/18639 0.04 2.02597826086957 0.392771959330882 0.729430861550686 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/368 25/18639 0.04 2.02597826086957 0.392771959330882 0.729430861550686 GO:0015645 fatty acid ligase activity 1/368 25/18639 0.04 2.02597826086957 0.392771959330882 0.729430861550686 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/368 25/18639 0.04 2.02597826086957 0.392771959330882 0.729430861550686 GO:0120020 cholesterol transfer activity 1/368 25/18639 0.04 2.02597826086957 0.392771959330882 0.729430861550686 GO:0120515 fatty acid-CoA ligase activity 1/368 25/18639 0.04 2.02597826086957 0.392771959330882 0.729430861550686 GO:0005178 integrin binding 4/368 161/18639 0.0248447204968944 1.25837159060221 0.393284508870834 0.729430861550686 GO:0003713 transcription coactivator activity 6/368 256/18639 0.0234375 1.18709663722826 0.393704424660566 0.729430861550686 GO:0035401 histone H3Y41 kinase activity 3/368 115/18639 0.0260869565217391 1.32129017013233 0.39704754000839 0.729430861550686 GO:0140801 histone H2AXY142 kinase activity 3/368 115/18639 0.0260869565217391 1.32129017013233 0.39704754000839 0.729430861550686 GO:0141003 histone H2AX kinase activity 8/368 354/18639 0.0225988700564972 1.14462048636699 0.399609607355447 0.729430861550686 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/368 26/18639 0.0384615384615385 1.94805602006689 0.40477689749389 0.729430861550686 GO:0005160 transforming growth factor beta receptor binding 1/368 26/18639 0.0384615384615385 1.94805602006689 0.40477689749389 0.729430861550686 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/368 26/18639 0.0384615384615385 1.94805602006689 0.40477689749389 0.729430861550686 GO:0008143 poly(A) binding 1/368 26/18639 0.0384615384615385 1.94805602006689 0.40477689749389 0.729430861550686 GO:0008157 protein phosphatase 1 binding 1/368 26/18639 0.0384615384615385 1.94805602006689 0.40477689749389 0.729430861550686 GO:0008198 ferrous iron binding 1/368 26/18639 0.0384615384615385 1.94805602006689 0.40477689749389 0.729430861550686 GO:0015145 monosaccharide transmembrane transporter activity 1/368 26/18639 0.0384615384615385 1.94805602006689 0.40477689749389 0.729430861550686 GO:0030247 polysaccharide binding 1/368 26/18639 0.0384615384615385 1.94805602006689 0.40477689749389 0.729430861550686 GO:0030507 spectrin binding 1/368 26/18639 0.0384615384615385 1.94805602006689 0.40477689749389 0.729430861550686 GO:0050750 low-density lipoprotein particle receptor binding 1/368 26/18639 0.0384615384615385 1.94805602006689 0.40477689749389 0.729430861550686 GO:0070006 metalloaminopeptidase activity 1/368 26/18639 0.0384615384615385 1.94805602006689 0.40477689749389 0.729430861550686 GO:0015081 sodium ion transmembrane transporter activity 4/368 164/18639 0.024390243902439 1.2353525980912 0.406654162102031 0.730934788803908 GO:0140996 histone H3 kinase activity 8/368 357/18639 0.0224089635854342 1.13500182681768 0.408609383384313 0.732570787090545 GO:0140299 molecular sensor activity 2/368 71/18639 0.028169014084507 1.4267452541335 0.410419836795655 0.733939555086107 GO:0004364 glutathione transferase activity 1/368 27/18639 0.037037037037037 1.87590579710145 0.416545129467363 0.737369029688438 GO:0016405 CoA-ligase activity 1/368 27/18639 0.037037037037037 1.87590579710145 0.416545129467363 0.737369029688438 GO:0023026 MHC class II protein complex binding 1/368 27/18639 0.037037037037037 1.87590579710145 0.416545129467363 0.737369029688438 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/368 27/18639 0.037037037037037 1.87590579710145 0.416545129467363 0.737369029688438 GO:0035173 histone kinase activity 8/368 360/18639 0.0222222222222222 1.12554347826087 0.417606861551057 0.737386423041036 GO:0043539 protein serine/threonine kinase activator activity 2/368 73/18639 0.0273972602739726 1.38765634306135 0.424116278803605 0.740257528565825 GO:0005201 extracellular matrix structural constituent 4/368 168/18639 0.0238095238095238 1.20593944099379 0.424388673825266 0.740257528565825 GO:0045499 chemorepellent activity 1/368 28/18639 0.0357142857142857 1.80890916149068 0.428081310015182 0.740257528565825 GO:0046875 ephrin receptor binding 1/368 28/18639 0.0357142857142857 1.80890916149068 0.428081310015182 0.740257528565825 GO:0051019 mitogen-activated protein kinase binding 1/368 28/18639 0.0357142857142857 1.80890916149068 0.428081310015182 0.740257528565825 GO:0051119 sugar transmembrane transporter activity 1/368 28/18639 0.0357142857142857 1.80890916149068 0.428081310015182 0.740257528565825 GO:0003697 single-stranded DNA binding 3/368 121/18639 0.0247933884297521 1.25577164929932 0.428736885303459 0.740257528565825 GO:0015108 chloride transmembrane transporter activity 3/368 121/18639 0.0247933884297521 1.25577164929932 0.428736885303459 0.740257528565825 GO:0051082 unfolded protein binding 3/368 121/18639 0.0247933884297521 1.25577164929932 0.428736885303459 0.740257528565825 GO:0016757 glycosyltransferase activity 6/368 267/18639 0.0224719101123595 1.13819003419638 0.432356354746631 0.744672738765082 GO:0019003 GDP binding 2/368 75/18639 0.0266666666666667 1.35065217391304 0.437646221840417 0.749421877933881 GO:0005416 amino acid:monoatomic cation symporter activity 1/368 29/18639 0.0344827586206897 1.74653298350825 0.439390002611733 0.749421877933881 GO:0051861 glycolipid binding 1/368 29/18639 0.0344827586206897 1.74653298350825 0.439390002611733 0.749421877933881 GO:0099604 ligand-gated calcium channel activity 1/368 29/18639 0.0344827586206897 1.74653298350825 0.439390002611733 0.749421877933881 GO:0017022 myosin binding 2/368 76/18639 0.0263157894736842 1.33288043478261 0.444346242996206 0.754539894711203 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 1/368 30/18639 0.0333333333333333 1.6883152173913 0.450475681227471 0.754539894711203 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/368 30/18639 0.0333333333333333 1.6883152173913 0.450475681227471 0.754539894711203 GO:0015215 nucleotide transmembrane transporter activity 1/368 30/18639 0.0333333333333333 1.6883152173913 0.450475681227471 0.754539894711203 GO:0033612 receptor serine/threonine kinase binding 1/368 30/18639 0.0333333333333333 1.6883152173913 0.450475681227471 0.754539894711203 GO:0048019 receptor antagonist activity 1/368 30/18639 0.0333333333333333 1.6883152173913 0.450475681227471 0.754539894711203 GO:0070566 adenylyltransferase activity 1/368 30/18639 0.0333333333333333 1.6883152173913 0.450475681227471 0.754539894711203 GO:0003724 RNA helicase activity 2/368 77/18639 0.025974025974026 1.31557029926595 0.451001734499278 0.754539894711203 GO:0004252 serine-type endopeptidase activity 4/368 176/18639 0.0227272727272727 1.15112401185771 0.459429660404801 0.757379988730301 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/368 31/18639 0.032258064516129 1.63385343618513 0.461342732079655 0.757379988730301 GO:0016411 acylglycerol O-acyltransferase activity 1/368 31/18639 0.032258064516129 1.63385343618513 0.461342732079655 0.757379988730301 GO:0016878 acid-thiol ligase activity 1/368 31/18639 0.032258064516129 1.63385343618513 0.461342732079655 0.757379988730301 GO:0017147 Wnt-protein binding 1/368 31/18639 0.032258064516129 1.63385343618513 0.461342732079655 0.757379988730301 GO:0047499 calcium-independent phospholipase A2 activity 1/368 31/18639 0.032258064516129 1.63385343618513 0.461342732079655 0.757379988730301 GO:0070325 lipoprotein particle receptor binding 1/368 31/18639 0.032258064516129 1.63385343618513 0.461342732079655 0.757379988730301 GO:0072349 modified amino acid transmembrane transporter activity 1/368 31/18639 0.032258064516129 1.63385343618513 0.461342732079655 0.757379988730301 GO:0008186 ATP-dependent activity, acting on RNA 2/368 79/18639 0.0253164556962025 1.28226472206935 0.464175756200355 0.75794196220285 GO:0033293 monocarboxylic acid binding 2/368 79/18639 0.0253164556962025 1.28226472206935 0.464175756200355 0.75794196220285 GO:0031490 chromatin DNA binding 3/368 128/18639 0.0234375 1.18709663722826 0.464928735730707 0.75794196220285 GO:0031369 translation initiation factor binding 1/368 32/18639 0.03125 1.58279551630435 0.471995455348931 0.762370539630416 GO:0047498 calcium-dependent phospholipase A2 activity 1/368 32/18639 0.03125 1.58279551630435 0.471995455348931 0.762370539630416 GO:0070717 poly-purine tract binding 1/368 32/18639 0.03125 1.58279551630435 0.471995455348931 0.762370539630416 GO:0120015 sterol transfer activity 1/368 32/18639 0.03125 1.58279551630435 0.471995455348931 0.762370539630416 GO:0001618 virus receptor activity 2/368 81/18639 0.0246913580246914 1.2506038647343 0.477162041544349 0.76562076245835 GO:0030971 receptor tyrosine kinase binding 2/368 81/18639 0.0246913580246914 1.2506038647343 0.477162041544349 0.76562076245835 GO:0019956 chemokine binding 1/368 33/18639 0.0303030303030303 1.53483201581028 0.482438066862426 0.76562076245835 GO:0030296 protein tyrosine kinase activator activity 1/368 33/18639 0.0303030303030303 1.53483201581028 0.482438066862426 0.76562076245835 GO:0140311 protein sequestering activity 1/368 33/18639 0.0303030303030303 1.53483201581028 0.482438066862426 0.76562076245835 GO:0140272 exogenous protein binding 2/368 82/18639 0.024390243902439 1.2353525980912 0.483583041281216 0.76562076245835 GO:0001540 amyloid-beta binding 2/368 83/18639 0.0240963855421687 1.22046883184914 0.489955107666929 0.76562076245835 GO:0005254 chloride channel activity 2/368 83/18639 0.0240963855421687 1.22046883184914 0.489955107666929 0.76562076245835 GO:0005125 cytokine activity 5/368 234/18639 0.0213675213675214 1.08225334448161 0.492382182704339 0.76562076245835 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/368 34/18639 0.0294117647058824 1.48968989769821 0.492674699744003 0.76562076245835 GO:0016831 carboxy-lyase activity 1/368 34/18639 0.0294117647058824 1.48968989769821 0.492674699744003 0.76562076245835 GO:0030332 cyclin binding 1/368 34/18639 0.0294117647058824 1.48968989769821 0.492674699744003 0.76562076245835 GO:0051427 hormone receptor binding 1/368 34/18639 0.0294117647058824 1.48968989769821 0.492674699744003 0.76562076245835 GO:0015291 secondary active transmembrane transporter activity 6/368 287/18639 0.0209059233449477 1.05887365550674 0.501339544659431 0.76562076245835 GO:0004623 phospholipase A2 activity 1/368 35/18639 0.0285714285714286 1.44712732919255 0.502709406032324 0.76562076245835 GO:0005154 epidermal growth factor receptor binding 1/368 35/18639 0.0285714285714286 1.44712732919255 0.502709406032324 0.76562076245835 GO:0061631 ubiquitin conjugating enzyme activity 1/368 35/18639 0.0285714285714286 1.44712732919255 0.502709406032324 0.76562076245835 GO:0019838 growth factor binding 3/368 136/18639 0.0220588235294118 1.11726742327366 0.505009629719241 0.76562076245835 GO:0099094 ligand-gated monoatomic cation channel activity 3/368 136/18639 0.0220588235294118 1.11726742327366 0.505009629719241 0.76562076245835 GO:0031406 carboxylic acid binding 4/368 187/18639 0.0213903743315508 1.08341083468961 0.506343476465591 0.76562076245835 GO:0046943 carboxylic acid transmembrane transporter activity 4/368 188/18639 0.0212765957446809 1.07764801110083 0.510520823231659 0.76562076245835 GO:0140597 protein carrier chaperone 4/368 188/18639 0.0212765957446809 1.07764801110083 0.510520823231659 0.76562076245835 GO:0004033 aldo-keto reductase (NADPH) activity 1/368 36/18639 0.0277777777777778 1.40692934782609 0.512546158267333 0.76562076245835 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/368 36/18639 0.0277777777777778 1.40692934782609 0.512546158267333 0.76562076245835 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/368 36/18639 0.0277777777777778 1.40692934782609 0.512546158267333 0.76562076245835 GO:0045505 dynein intermediate chain binding 1/368 36/18639 0.0277777777777778 1.40692934782609 0.512546158267333 0.76562076245835 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/368 36/18639 0.0277777777777778 1.40692934782609 0.512546158267333 0.76562076245835 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/368 36/18639 0.0277777777777778 1.40692934782609 0.512546158267333 0.76562076245835 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/368 36/18639 0.0277777777777778 1.40692934782609 0.512546158267333 0.76562076245835 GO:0005342 organic acid transmembrane transporter activity 4/368 189/18639 0.0211640211640212 1.07194616977226 0.514682163974952 0.76562076245835 GO:0043177 organic acid binding 4/368 189/18639 0.0211640211640212 1.07194616977226 0.514682163974952 0.76562076245835 GO:0016651 oxidoreductase activity, acting on NAD(P)H 2/368 88/18639 0.0227272727272727 1.15112401185771 0.521062762091601 0.76562076245835 GO:0023023 MHC protein complex binding 1/368 37/18639 0.027027027027027 1.36890423031727 0.522188851045789 0.76562076245835 GO:0030551 cyclic nucleotide binding 1/368 37/18639 0.027027027027027 1.36890423031727 0.522188851045789 0.76562076245835 GO:0043394 proteoglycan binding 1/368 37/18639 0.027027027027027 1.36890423031727 0.522188851045789 0.76562076245835 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 5/368 243/18639 0.0205761316872428 1.04216988727858 0.525707941469269 0.76562076245835 GO:0042162 telomeric DNA binding 1/368 38/18639 0.0263157894736842 1.33288043478261 0.531641302546442 0.76562076245835 GO:0004676 3-phosphoinositide-dependent protein kinase activity 5/368 245/18639 0.0204081632653061 1.03366237799468 0.532985637774144 0.76562076245835 GO:0004711 ribosomal protein S6 kinase activity 5/368 245/18639 0.0204081632653061 1.03366237799468 0.532985637774144 0.76562076245835 GO:0035175 histone H3S10 kinase activity 5/368 245/18639 0.0204081632653061 1.03366237799468 0.532985637774144 0.76562076245835 GO:0035979 histone H2AXS139 kinase activity 5/368 245/18639 0.0204081632653061 1.03366237799468 0.532985637774144 0.76562076245835 GO:0044022 histone H3S28 kinase activity 5/368 245/18639 0.0204081632653061 1.03366237799468 0.532985637774144 0.76562076245835 GO:0044023 histone H4S1 kinase activity 5/368 245/18639 0.0204081632653061 1.03366237799468 0.532985637774144 0.76562076245835 GO:0044024 histone H2AS1 kinase activity 5/368 245/18639 0.0204081632653061 1.03366237799468 0.532985637774144 0.76562076245835 GO:0044025 histone H2BS14 kinase activity 5/368 245/18639 0.0204081632653061 1.03366237799468 0.532985637774144 0.76562076245835 GO:0072354 histone H3T3 kinase activity 5/368 245/18639 0.0204081632653061 1.03366237799468 0.532985637774144 0.76562076245835 GO:0072371 histone H2AS121 kinase activity 5/368 245/18639 0.0204081632653061 1.03366237799468 0.532985637774144 0.76562076245835 GO:0072518 Rho-dependent protein serine/threonine kinase activity 5/368 245/18639 0.0204081632653061 1.03366237799468 0.532985637774144 0.76562076245835 GO:0140823 histone H2BS36 kinase activity 5/368 245/18639 0.0204081632653061 1.03366237799468 0.532985637774144 0.76562076245835 GO:0140855 histone H3S57 kinase activity 5/368 245/18639 0.0204081632653061 1.03366237799468 0.532985637774144 0.76562076245835 GO:0140995 histone H2A kinase activity 5/368 245/18639 0.0204081632653061 1.03366237799468 0.532985637774144 0.76562076245835 GO:0140997 histone H4 kinase activity 5/368 245/18639 0.0204081632653061 1.03366237799468 0.532985637774144 0.76562076245835 GO:0140998 histone H2B kinase activity 5/368 245/18639 0.0204081632653061 1.03366237799468 0.532985637774144 0.76562076245835 GO:1990244 histone H2AT120 kinase activity 5/368 245/18639 0.0204081632653061 1.03366237799468 0.532985637774144 0.76562076245835 GO:0004677 DNA-dependent protein kinase activity 5/368 246/18639 0.0203252032520325 1.02946049840933 0.536605710733894 0.767562725655538 GO:0140857 histone H3T45 kinase activity 5/368 246/18639 0.0203252032520325 1.02946049840933 0.536605710733894 0.767562725655538 GO:0033218 amide binding 5/368 247/18639 0.0202429149797571 1.02529264214047 0.540212993778651 0.767562725655538 GO:0035403 histone H3T6 kinase activity 5/368 247/18639 0.0202429149797571 1.02529264214047 0.540212993778651 0.767562725655538 GO:0000217 DNA secondary structure binding 1/368 39/18639 0.0256410256410256 1.29870401337793 0.540907256025444 0.767562725655538 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/368 39/18639 0.0256410256410256 1.29870401337793 0.540907256025444 0.767562725655538 GO:0004679 AMP-activated protein kinase activity 5/368 248/18639 0.0201612903225806 1.02115839761571 0.543807287635489 0.76850997725095 GO:0042277 peptide binding 5/368 249/18639 0.0200803212851406 1.01705735987428 0.547388397460562 0.76850997725095 GO:0008194 UDP-glycosyltransferase activity 3/368 145/18639 0.0206896551724138 1.04791979010495 0.548176584150819 0.76850997725095 GO:0015144 carbohydrate transmembrane transporter activity 1/368 40/18639 0.025 1.26623641304348 0.549990381282575 0.76850997725095 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/368 40/18639 0.025 1.26623641304348 0.549990381282575 0.76850997725095 GO:0030331 nuclear estrogen receptor binding 1/368 40/18639 0.025 1.26623641304348 0.549990381282575 0.76850997725095 GO:0140662 ATP-dependent protein folding chaperone 1/368 40/18639 0.025 1.26623641304348 0.549990381282575 0.76850997725095 GO:0022804 active transmembrane transporter activity 9/368 457/18639 0.0196936542669584 0.997472885548473 0.550345233352321 0.76850997725095 GO:0042562 hormone binding 2/368 94/18639 0.0212765957446809 1.07764801110083 0.556681947112117 0.772751257485795 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/368 41/18639 0.024390243902439 1.2353525980912 0.558894276098856 0.772751257485795 GO:0008137 NADH dehydrogenase (ubiquinone) activity 1/368 41/18639 0.024390243902439 1.2353525980912 0.558894276098856 0.772751257485795 GO:0017080 sodium channel regulator activity 1/368 41/18639 0.024390243902439 1.2353525980912 0.558894276098856 0.772751257485795 GO:0061650 ubiquitin-like protein conjugating enzyme activity 1/368 41/18639 0.024390243902439 1.2353525980912 0.558894276098856 0.772751257485795 GO:0008509 monoatomic anion transmembrane transporter activity 3/368 149/18639 0.0201342281879195 1.0197877152028 0.566641611812164 0.777154980117022 GO:0004520 DNA endonuclease activity 1/368 42/18639 0.0238095238095238 1.20593944099379 0.567622467646099 0.777154980117022 GO:0016859 cis-trans isomerase activity 1/368 42/18639 0.0238095238095238 1.20593944099379 0.567622467646099 0.777154980117022 GO:0019894 kinesin binding 1/368 42/18639 0.0238095238095238 1.20593944099379 0.567622467646099 0.777154980117022 GO:0048487 beta-tubulin binding 1/368 42/18639 0.0238095238095238 1.20593944099379 0.567622467646099 0.777154980117022 GO:0019842 vitamin binding 3/368 150/18639 0.02 1.01298913043478 0.571185275647276 0.780508534558948 GO:0000510 H3-H4 histone complex chaperone activity 3/368 151/18639 0.0198675496688742 1.00628059314714 0.575699429608118 0.780590522544082 GO:0140584 chromatin extrusion motor activity 3/368 151/18639 0.0198675496688742 1.00628059314714 0.575699429608118 0.780590522544082 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 3/368 151/18639 0.0198675496688742 1.00628059314714 0.575699429608118 0.780590522544082 GO:0140849 ATP-dependent H2AZ histone chaperone activity 3/368 151/18639 0.0198675496688742 1.00628059314714 0.575699429608118 0.780590522544082 GO:0005249 voltage-gated potassium channel activity 2/368 98/18639 0.0204081632653061 1.03366237799468 0.579364233132585 0.780631257692445 GO:0042626 ATPase-coupled transmembrane transporter activity 2/368 98/18639 0.0204081632653061 1.03366237799468 0.579364233132585 0.780631257692445 GO:0015616 DNA translocase activity 3/368 152/18639 0.0197368421052632 0.999660326086957 0.58018385914089 0.780631257692445 GO:0140674 ATP-dependent histone chaperone activity 3/368 152/18639 0.0197368421052632 0.999660326086957 0.58018385914089 0.780631257692445 GO:0001046 core promoter sequence-specific DNA binding 1/368 44/18639 0.0227272727272727 1.15112401185771 0.584565504839917 0.780631412547505 GO:0003954 NADH dehydrogenase activity 1/368 44/18639 0.0227272727272727 1.15112401185771 0.584565504839917 0.780631412547505 GO:0030020 extracellular matrix structural constituent conferring tensile strength 1/368 44/18639 0.0227272727272727 1.15112401185771 0.584565504839917 0.780631412547505 GO:0061775 cohesin loader activity 3/368 153/18639 0.0196078431372549 0.993126598465473 0.584638361750984 0.780631412547505 GO:0005506 iron ion binding 3/368 154/18639 0.0194805194805195 0.986677724449464 0.589062746767968 0.785043698639441 GO:0043130 ubiquitin binding 2/368 100/18639 0.02 1.01298913043478 0.590382657304455 0.785309758577653 GO:0003730 mRNA 3'-UTR binding 5/368 262/18639 0.0190839694656489 0.966592681712579 0.592662339736187 0.785526903451263 GO:0140303 intramembrane lipid transporter activity 1/368 45/18639 0.0222222222222222 1.12554347826087 0.592787064088043 0.785526903451263 GO:0008094 ATP-dependent activity, acting on DNA 4/368 210/18639 0.019047619047619 0.964751552795031 0.597910200929928 0.790820850663924 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/368 46/18639 0.0217391304347826 1.10107514177694 0.60084634990151 0.791716712934132 GO:0030291 protein serine/threonine kinase inhibitor activity 1/368 46/18639 0.0217391304347826 1.10107514177694 0.60084634990151 0.791716712934132 GO:0005253 monoatomic anion channel activity 2/368 103/18639 0.0194174757281553 0.983484592655129 0.606505703498199 0.794411878463008 GO:0005504 fatty acid binding 1/368 47/18639 0.0212765957446809 1.07764801110083 0.608746556604906 0.794411878463008 GO:0061749 forked DNA-dependent helicase activity 1/368 47/18639 0.0212765957446809 1.07764801110083 0.608746556604906 0.794411878463008 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/368 47/18639 0.0212765957446809 1.07764801110083 0.608746556604906 0.794411878463008 GO:0003689 DNA clamp loader activity 3/368 160/18639 0.01875 0.949677309782609 0.614967341213672 0.794411878463008 GO:0099106 ion channel regulator activity 3/368 160/18639 0.01875 0.949677309782609 0.614967341213672 0.794411878463008 GO:0009378 four-way junction helicase activity 1/368 48/18639 0.0208333333333333 1.05519701086957 0.616490815811521 0.794411878463008 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/368 48/18639 0.0208333333333333 1.05519701086957 0.616490815811521 0.794411878463008 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/368 48/18639 0.0208333333333333 1.05519701086957 0.616490815811521 0.794411878463008 GO:0036121 double-stranded DNA helicase activity 1/368 48/18639 0.0208333333333333 1.05519701086957 0.616490815811521 0.794411878463008 GO:0043138 3'-5' DNA helicase activity 1/368 48/18639 0.0208333333333333 1.05519701086957 0.616490815811521 0.794411878463008 GO:0140693 molecular condensate scaffold activity 1/368 48/18639 0.0208333333333333 1.05519701086957 0.616490815811521 0.794411878463008 GO:0008013 beta-catenin binding 2/368 106/18639 0.0188679245283019 0.955650123051682 0.622143567867791 0.799783584192847 GO:0035254 glutamate receptor binding 1/368 49/18639 0.0204081632653061 1.03366237799468 0.624082197651194 0.799783584192847 GO:0060590 ATPase regulator activity 1/368 49/18639 0.0204081632653061 1.03366237799468 0.624082197651194 0.799783584192847 GO:0005017 platelet-derived growth factor receptor activity 1/368 50/18639 0.02 1.01298913043478 0.631523711974183 0.80210677125105 GO:0005019 platelet-derived growth factor beta-receptor activity 1/368 50/18639 0.02 1.01298913043478 0.631523711974183 0.80210677125105 GO:0015605 organophosphate ester transmembrane transporter activity 1/368 50/18639 0.02 1.01298913043478 0.631523711974183 0.80210677125105 GO:0032813 tumor necrosis factor receptor superfamily binding 1/368 50/18639 0.02 1.01298913043478 0.631523711974183 0.80210677125105 GO:0140713 histone chaperone activity 3/368 164/18639 0.0182926829268293 0.926514448568399 0.631616173652753 0.80210677125105 GO:0015103 inorganic anion transmembrane transporter activity 3/368 165/18639 0.0181818181818182 0.920899209486166 0.63569983227971 0.805832879616775 GO:0005272 sodium channel activity 1/368 51/18639 0.0196078431372549 0.993126598465473 0.638818309531529 0.806593703119775 GO:0030544 Hsp70 protein binding 1/368 51/18639 0.0196078431372549 0.993126598465473 0.638818309531529 0.806593703119775 GO:0015399 primary active transmembrane transporter activity 3/368 166/18639 0.0180722891566265 0.915351623886852 0.63975192430042 0.806593703119775 GO:0016874 ligase activity 3/368 167/18639 0.0179640718562874 0.909870476438428 0.643772392163085 0.810061157559553 GO:0005080 protein kinase C binding 1/368 52/18639 0.0192307692307692 0.974028010033445 0.645968883132368 0.810061157559553 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/368 52/18639 0.0192307692307692 0.974028010033445 0.645968883132368 0.810061157559553 GO:0016247 channel regulator activity 3/368 168/18639 0.0178571428571429 0.904454580745342 0.647761187041955 0.810858200207876 GO:0017046 peptide hormone binding 1/368 53/18639 0.0188679245283019 0.955650123051682 0.652978268778642 0.81159178442168 GO:0034212 protein N-acetyltransferase activity 1/368 53/18639 0.0188679245283019 0.955650123051682 0.652978268778642 0.81159178442168 GO:0051018 protein kinase A binding 1/368 53/18639 0.0188679245283019 0.955650123051682 0.652978268778642 0.81159178442168 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/368 53/18639 0.0188679245283019 0.955650123051682 0.652978268778642 0.81159178442168 GO:0140097 catalytic activity, acting on DNA 6/368 336/18639 0.0178571428571429 0.904454580745342 0.654492976913321 0.811917567256288 GO:0141108 transporter regulator activity 3/368 170/18639 0.0176470588235294 0.893813938618926 0.655643604947253 0.811917567256288 GO:0015485 cholesterol binding 1/368 54/18639 0.0185185185185185 0.937952898550725 0.659849246777644 0.811917567256288 GO:0050661 NADP binding 1/368 54/18639 0.0185185185185185 0.937952898550725 0.659849246777644 0.811917567256288 GO:0051287 NAD binding 1/368 54/18639 0.0185185185185185 0.937952898550725 0.659849246777644 0.811917567256288 GO:0031267 small GTPase binding 5/368 283/18639 0.0176678445229682 0.894866722998925 0.660189747983002 0.811917567256288 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 4/368 229/18639 0.0174672489082969 0.884706664135181 0.665390387458896 0.816409214979125 GO:0017124 SH3 domain binding 2/368 115/18639 0.0173913043478261 0.88086011342155 0.666171285261141 0.816409214979125 GO:1990782 protein tyrosine kinase binding 2/368 117/18639 0.0170940170940171 0.865802675585284 0.675375649276988 0.82624490426382 GO:0005319 lipid transporter activity 3/368 178/18639 0.0168539325842697 0.853642525647289 0.685902215827921 0.834874934962365 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 1/368 58/18639 0.0172413793103448 0.873266491754123 0.686002799626708 0.834874934962365 GO:0017116 single-stranded DNA helicase activity 1/368 58/18639 0.0172413793103448 0.873266491754123 0.686002799626708 0.834874934962365 GO:0032182 ubiquitin-like protein binding 2/368 120/18639 0.0166666666666667 0.844157608695652 0.688794683054621 0.836633311160498 GO:0031593 polyubiquitin modification-dependent protein binding 1/368 59/18639 0.0169491525423729 0.858465364775239 0.692221569861753 0.836633311160498 GO:0036002 pre-mRNA binding 1/368 59/18639 0.0169491525423729 0.858465364775239 0.692221569861753 0.836633311160498 GO:0070063 RNA polymerase binding 1/368 59/18639 0.0169491525423729 0.858465364775239 0.692221569861753 0.836633311160498 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 3/368 181/18639 0.0165745856353591 0.839493754503963 0.696725705537764 0.836787300052064 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/368 122/18639 0.0163934426229508 0.830318959372773 0.697485439102783 0.836787300052064 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 2/368 122/18639 0.0163934426229508 0.830318959372773 0.697485439102783 0.836787300052064 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/368 60/18639 0.0166666666666667 0.844157608695652 0.698317504323049 0.836787300052064 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/368 60/18639 0.0166666666666667 0.844157608695652 0.698317504323049 0.836787300052064 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/368 61/18639 0.0163934426229508 0.830318959372773 0.704293022833685 0.839641852051724 GO:0016836 hydro-lyase activity 1/368 61/18639 0.0163934426229508 0.830318959372773 0.704293022833685 0.839641852051724 GO:0019905 syntaxin binding 1/368 61/18639 0.0163934426229508 0.830318959372773 0.704293022833685 0.839641852051724 GO:0005267 potassium channel activity 2/368 124/18639 0.0161290322580645 0.816926718092567 0.705974638957782 0.840217694243472 GO:0015078 proton transmembrane transporter activity 3/368 185/18639 0.0162162162162162 0.821342538190364 0.71071565801546 0.844426569947182 GO:0015276 ligand-gated monoatomic ion channel activity 3/368 186/18639 0.0161290322580645 0.816926718092567 0.71413476010869 0.846777756073738 GO:0004519 endonuclease activity 2/368 127/18639 0.015748031496063 0.797629236562821 0.718335864525437 0.846777756073738 GO:0019783 ubiquitin-like protein peptidase activity 2/368 127/18639 0.015748031496063 0.797629236562821 0.718335864525437 0.846777756073738 GO:0016887 ATP hydrolysis activity 7/368 417/18639 0.0167865707434053 0.850230685017204 0.719713710079446 0.846777756073738 GO:0022834 ligand-gated channel activity 3/368 188/18639 0.0159574468085106 0.808236008325624 0.720879448038503 0.846777756073738 GO:0004536 DNA nuclease activity 1/368 64/18639 0.015625 0.791397758152174 0.72152057333348 0.846777756073738 GO:0042393 histone binding 4/368 247/18639 0.0161943319838057 0.820234113712375 0.721823577885716 0.846777756073738 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 2/368 128/18639 0.015625 0.791397758152174 0.722358199903131 0.846777756073738 GO:0120013 lipid transfer activity 1/368 65/18639 0.0153846153846154 0.779222408026756 0.727037689296509 0.850123081283645 GO:0140104 molecular carrier activity 4/368 249/18639 0.0160642570281124 0.813645887899424 0.727637444750624 0.850123081283645 GO:0008235 metalloexopeptidase activity 1/368 66/18639 0.0151515151515152 0.767416007905138 0.732445793654154 0.854316973962665 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/368 132/18639 0.0151515151515152 0.767416007905138 0.737966133452073 0.859326012541367 GO:0005548 phospholipid transporter activity 1/368 68/18639 0.0147058823529412 0.744844948849105 0.742943518076108 0.860832076316284 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 1/368 68/18639 0.0147058823529412 0.744844948849105 0.742943518076108 0.860832076316284 GO:0032934 sterol binding 1/368 68/18639 0.0147058823529412 0.744844948849105 0.742943518076108 0.860832076316284 GO:0002039 p53 binding 1/368 69/18639 0.0144927536231884 0.734050094517958 0.748037308682322 0.863878341657838 GO:0008080 N-acetyltransferase activity 1/368 69/18639 0.0144927536231884 0.734050094517958 0.748037308682322 0.863878341657838 GO:0016779 nucleotidyltransferase activity 2/368 136/18639 0.0147058823529412 0.744844948849105 0.752820708634853 0.867972560449065 GO:0005518 collagen binding 1/368 72/18639 0.0138888888888889 0.703464673913043 0.762722565043307 0.87594172358663 GO:0070851 growth factor receptor binding 2/368 139/18639 0.0143884892086331 0.728769158586175 0.763481302584067 0.87594172358663 GO:0140767 enzyme-substrate adaptor activity 2/368 139/18639 0.0143884892086331 0.728769158586175 0.763481302584067 0.87594172358663 GO:0004521 RNA endonuclease activity 1/368 73/18639 0.0136986301369863 0.693828171530673 0.767425430129969 0.879028147910308 GO:0003678 DNA helicase activity 1/368 74/18639 0.0135135135135135 0.684452115158637 0.772035332193535 0.879994744500274 GO:0003684 damaged DNA binding 1/368 74/18639 0.0135135135135135 0.684452115158637 0.772035332193535 0.879994744500274 GO:0031491 nucleosome binding 1/368 74/18639 0.0135135135135135 0.684452115158637 0.772035332193535 0.879994744500274 GO:0044183 protein folding chaperone 1/368 75/18639 0.0133333333333333 0.675326086956522 0.776554103955064 0.88159333818507 GO:0022843 voltage-gated monoatomic cation channel activity 2/368 143/18639 0.013986013986014 0.708384007297051 0.777074372480696 0.88159333818507 GO:0019903 protein phosphatase binding 2/368 144/18639 0.0138888888888889 0.703464673913043 0.780364306910835 0.88159333818507 GO:0019955 cytokine binding 2/368 144/18639 0.0138888888888889 0.703464673913043 0.780364306910835 0.88159333818507 GO:0008514 organic anion transmembrane transporter activity 4/368 269/18639 0.0148698884758364 0.753151769839987 0.780846383494913 0.88159333818507 GO:0051536 iron-sulfur cluster binding 1/368 76/18639 0.0131578947368421 0.666440217391304 0.780983542101182 0.88159333818507 GO:0051540 metal cluster binding 1/368 77/18639 0.012987012987013 0.657785149632976 0.785325407990681 0.884053410356258 GO:0005096 GTPase activator activity 4/368 271/18639 0.014760147601476 0.747593454195411 0.78568512789151 0.884053410356258 GO:0019199 transmembrane receptor protein kinase activity 1/368 78/18639 0.0128205128205128 0.649352006688963 0.789581428347293 0.886555996866991 GO:0016791 phosphatase activity 4/368 273/18639 0.0146520146520147 0.742116579073101 0.790438656265149 0.886555996866991 GO:0015101 organic cation transmembrane transporter activity 1/368 81/18639 0.0123456790123457 0.62530193236715 0.80185117810232 0.886589394084742 GO:0033192 calmodulin-dependent protein phosphatase activity 1/368 81/18639 0.0123456790123457 0.62530193236715 0.80185117810232 0.886589394084742 GO:0140791 histone H2AXS140 phosphatase activity 1/368 81/18639 0.0123456790123457 0.62530193236715 0.80185117810232 0.886589394084742 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/368 81/18639 0.0123456790123457 0.62530193236715 0.80185117810232 0.886589394084742 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/368 81/18639 0.0123456790123457 0.62530193236715 0.80185117810232 0.886589394084742 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/368 81/18639 0.0123456790123457 0.62530193236715 0.80185117810232 0.886589394084742 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/368 81/18639 0.0123456790123457 0.62530193236715 0.80185117810232 0.886589394084742 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/368 81/18639 0.0123456790123457 0.62530193236715 0.80185117810232 0.886589394084742 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/368 81/18639 0.0123456790123457 0.62530193236715 0.80185117810232 0.886589394084742 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/368 82/18639 0.0121951219512195 0.617676299045599 0.805780414359371 0.888132186267168 GO:0033549 MAP kinase phosphatase activity 1/368 82/18639 0.0121951219512195 0.617676299045599 0.805780414359371 0.888132186267168 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/368 83/18639 0.0120481927710843 0.610234415924568 0.809631942489766 0.889579924271671 GO:0030165 PDZ domain binding 1/368 83/18639 0.0120481927710843 0.610234415924568 0.809631942489766 0.889579924271671 GO:0017018 myosin phosphatase activity 1/368 84/18639 0.0119047619047619 0.602969720496894 0.813407295214694 0.890935178039845 GO:0051117 ATPase binding 1/368 84/18639 0.0119047619047619 0.602969720496894 0.813407295214694 0.890935178039845 GO:0140375 immune receptor activity 2/368 156/18639 0.0128205128205128 0.649352006688963 0.816637108728373 0.893077399716988 GO:0008081 phosphoric diester hydrolase activity 1/368 87/18639 0.0114942528735632 0.582177661169415 0.824291179447939 0.900043795627734 GO:0015079 potassium ion transmembrane transporter activity 2/368 160/18639 0.0125 0.633118206521739 0.827484308367818 0.901042501634151 GO:0004197 cysteine-type endopeptidase activity 1/368 88/18639 0.0113636363636364 0.575562005928854 0.827776563555483 0.901042501634151 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/368 89/18639 0.0112359550561798 0.569095017098192 0.831192995263293 0.901960200742366 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/368 89/18639 0.0112359550561798 0.569095017098192 0.831192995263293 0.901960200742366 GO:0140793 histone H2AXY142 phosphatase activity 1/368 90/18639 0.0111111111111111 0.562771739130435 0.834541835033811 0.903811131549383 GO:0005085 guanyl-nucleotide exchange factor activity 3/368 230/18639 0.0130434782608696 0.660645085066163 0.835477337009986 0.903811131549383 GO:0043178 alcohol binding 1/368 92/18639 0.0108695652173913 0.550537570888469 0.841042047284856 0.908429083430946 GO:0051213 dioxygenase activity 1/368 93/18639 0.010752688172043 0.544617812061711 0.844196008928204 0.910432926551801 GO:0042578 phosphoric ester hydrolase activity 5/368 363/18639 0.0137741046831956 0.697650916277399 0.846984930476516 0.910964076907933 GO:0016410 N-acyltransferase activity 1/368 94/18639 0.0106382978723404 0.538824005550416 0.84728755797999 0.910964076907933 GO:0008276 protein methyltransferase activity 1/368 95/18639 0.0105263157894737 0.533152173913043 0.850317926201255 0.912619331595575 GO:0030695 GTPase regulator activity 7/368 489/18639 0.0143149284253579 0.725043344891971 0.852622117609675 0.912619331595575 GO:0004896 cytokine receptor activity 1/368 96/18639 0.0104166666666667 0.527598505434783 0.853288321108391 0.912619331595575 GO:0060589 nucleoside-triphosphatase regulator activity 7/368 490/18639 0.0142857142857143 0.723563664596273 0.854034638411836 0.912619331595575 GO:0005244 voltage-gated monoatomic ion channel activity 2/368 173/18639 0.0115606936416185 0.585542849962302 0.858861359141684 0.915192683542317 GO:0004725 protein tyrosine phosphatase activity 1/368 98/18639 0.0102040816326531 0.516831188997338 0.859053902668823 0.915192683542317 GO:0003823 antigen binding 2/368 174/18639 0.0114942528735632 0.582177661169415 0.861045477995505 0.915434605675912 GO:0004721 phosphoprotein phosphatase activity 2/368 175/18639 0.0114285714285714 0.578850931677019 0.863198679531781 0.915434605675912 GO:0022832 voltage-gated channel activity 2/368 175/18639 0.0114285714285714 0.578850931677019 0.863198679531781 0.915434605675912 GO:0015171 amino acid transmembrane transporter activity 1/368 102/18639 0.00980392156862745 0.496563299232737 0.869915935044426 0.9211647590123 GO:0004722 protein serine/threonine phosphatase activity 1/368 103/18639 0.00970873786407767 0.491742296327564 0.872498388294879 0.922505837397753 GO:0000149 SNARE binding 1/368 106/18639 0.00943396226415094 0.477825061525841 0.879942982017811 0.927578993074414 GO:0004497 monooxygenase activity 1/368 106/18639 0.00943396226415094 0.477825061525841 0.879942982017811 0.927578993074414 GO:0046873 metal ion transmembrane transporter activity 6/368 450/18639 0.0133333333333333 0.675326086956522 0.882574529804535 0.927992181836568 GO:0004843 cysteine-type deubiquitinase activity 1/368 108/18639 0.00925925925925926 0.468976449275362 0.884663589770413 0.927992181836568 GO:0005496 steroid binding 1/368 108/18639 0.00925925925925926 0.468976449275362 0.884663589770413 0.927992181836568 GO:0008234 cysteine-type peptidase activity 2/368 187/18639 0.0106951871657754 0.541705417344803 0.886756065070967 0.927992181836568 GO:0004620 phospholipase activity 1/368 109/18639 0.00917431192660551 0.464673913043478 0.886954011170472 0.927992181836568 GO:0019902 phosphatase binding 2/368 190/18639 0.0105263157894737 0.533152173913043 0.892029157964108 0.93191123656161 GO:0101005 deubiquitinase activity 1/368 115/18639 0.00869565217391304 0.440430056710775 0.899774658572458 0.938604219731091 GO:0009055 electron transfer activity 1/368 116/18639 0.00862068965517241 0.436633245877061 0.901765747195074 0.939283490020426 GO:0022853 active monoatomic ion transmembrane transporter activity 1/368 118/18639 0.00847457627118644 0.42923268238762 0.905630354438157 0.941909315224255 GO:0004540 RNA nuclease activity 1/368 121/18639 0.00826446280991736 0.418590549766439 0.911144804766446 0.946147340730025 GO:0008528 G protein-coupled peptide receptor activity 1/368 122/18639 0.00819672131147541 0.415159479686386 0.912910584647964 0.946147340730025 GO:0008168 methyltransferase activity 2/368 204/18639 0.00980392156862745 0.496563299232737 0.913754279135844 0.946147340730025 GO:0004518 nuclease activity 2/368 209/18639 0.00956937799043062 0.484683794466403 0.920468249960791 0.95093809376441 GO:0042826 histone deacetylase binding 1/368 127/18639 0.0078740157480315 0.39881461828141 0.921228160198117 0.95093809376441 GO:0001653 peptide receptor activity 1/368 128/18639 0.0078125 0.395698879076087 0.922794065397291 0.95093809376441 GO:0035591 signaling adaptor activity 1/368 129/18639 0.00775193798449612 0.392631445904955 0.924328924882667 0.95093809376441 GO:0016298 lipase activity 1/368 130/18639 0.00769230769230769 0.389611204013378 0.925833352524113 0.95093809376441 GO:0005262 calcium channel activity 1/368 131/18639 0.00763358778625954 0.386637072685032 0.927307950085901 0.95093809376441 GO:0016741 transferase activity, transferring one-carbon groups 2/368 215/18639 0.00930232558139535 0.471157735085945 0.927876827581821 0.95093809376441 GO:0015297 antiporter activity 1/368 135/18639 0.00740740740740741 0.37518115942029 0.932919664328571 0.95468201923848 GO:0140789 histone phosphatase activity 1/368 136/18639 0.00735294117647059 0.372422474424552 0.934253730667043 0.95468201923848 GO:0140101 catalytic activity, acting on a tRNA 1/368 139/18639 0.00719424460431655 0.364384579293087 0.938099248895964 0.957216264157308 GO:0020037 heme binding 1/368 142/18639 0.00704225352112676 0.356686313533374 0.941720417053347 0.959514552840692 GO:0005216 monoatomic ion channel activity 5/368 448/18639 0.0111607142857143 0.565284112965839 0.943446889060597 0.959878474936834 GO:0015085 calcium ion transmembrane transporter activity 1/368 147/18639 0.00680272108843537 0.344554125998225 0.947292255687358 0.962394016285272 GO:0140098 catalytic activity, acting on RNA 4/368 387/18639 0.0103359173126615 0.523508594539939 0.949430079171361 0.963170022429991 GO:0022836 gated channel activity 3/368 318/18639 0.00943396226415094 0.477825061525841 0.95224823303057 0.963326445042286 GO:0046906 tetrapyrrole binding 1/368 152/18639 0.00657894736842105 0.333220108695652 0.952332705298579 0.963326445042286 GO:0005261 monoatomic cation channel activity 3/368 341/18639 0.00879765395894428 0.445596391686855 0.966182799387636 0.975928159035638 GO:0140030 modification-dependent protein binding 1/368 173/18639 0.00578034682080925 0.292771424981151 0.968757650026361 0.977121025422272 GO:0001664 G protein-coupled receptor binding 2/368 297/18639 0.00673400673400673 0.341073781291173 0.981924007348014 0.988978059124939 GO:0004842 ubiquitin-protein transferase activity 3/368 449/18639 0.0066815144766147 0.338415076982667 0.993861453308324 0.999443396063395 GO:0019787 ubiquitin-like protein transferase activity 3/368 479/18639 0.00626304801670146 0.317219978215485 0.996256127838781 0.999443396063395 GO:0016755 aminoacyltransferase activity 3/368 496/18639 0.00604838709677419 0.306347519284712 0.99718028370882 0.999443396063395 GO:0061630 ubiquitin protein ligase activity 1/368 353/18639 0.0028328611898017 0.143482879664983 0.999180810794067 0.999443396063395 GO:0061659 ubiquitin-like protein ligase activity 1/368 372/18639 0.00268817204301075 0.136154453015428 0.999443396063395 0.999443396063395